Test Club meetings

Next session: Tuesday, 13th October, 16.00 - 17.15, via Zoom.

We will have 3 short related talks:

Dr Katie Young will talk about her analysis of routine HbA1c data:

“HbA1c (glycated haemoglobin) measurements can be used to diagnose diabetes and monitor blood glucose control in those with diabetes. In UK Biobank, nearly all of the 500,000 participants had their HbA1c measured at recruitment, and we can use these measurements to find the proportion with undiagnosed diabetes and with 'pre-diabetes'. However, when we compared the HbA1c measurements from UK Biobank to those from the Exeter 10,000 project (EXTEND), we found some unexpected results that eventually led us to believe that UK Biobank HbA1c measurements are systematically lower than those from other sources, including those from the primary care (GP) records which UK Biobank have provided for some of their cohort. We're still working out why this might be!”

Zhivko Zhelev and Jaime Peters will share some observations from a recent rapid review for Public Health England. The focus of the review is the accuracy and effectiveness of HbA1c point-of-care tests when used for screening of pre-diabetes in the NHS Health Check https://www.nhs.uk/conditions/nhs-health-check/ and similar programmes.

Prof. Chris Hyde will present an update on the work of Alison Smith from Leeds on incorporating variability captured in evaluations of analytical validity into health economic evaluations of tests.


Future sessions

Tuesday 3rd November: Prof Sue Mallett, University College London, will discuss the methodological and disease challenges of RT-PCR testing for SARS-CoV-2 underlying the methods and presentation of results in an individual participant data review. This will be at 16.00 - 17.15 via Zoom, with details soon on how to attend.

Tuesday 1st December. This will be at 16.00 - 17.15 via Zoom, with details soon on how to attend.

Futher details will be published here and emailed to those on our notification list. If you would like to receive alerts about future sessions and similar events, please email Zhivko Zhelev.

About the Test Club

Test Club meetings aim to bring together clinicians, researchers and students interested in medical tests and diagnostics, to share and discuss experience, interests and challenges in this area.

The most recent meetings included:

  • Ethnic inequalities in diagnosis and outcomes of symptomatic cancer patients presented by Dr Tanimola Martins from the UoE DISCO group
  • Discussion of the recently published paper "An analysis reveals differences between pragmatic and explanatory diagnostic accuracy studies" by PM Bossuyt, M Olsena, C Hyde and JF Cohen
  • Competing risks models in screening for pre-eclampsia presented by Prof Dave Wright

You can find out more about past sessions and access slides/video, if available, in our archive!

If you'd like to present on a topic or discuss your work at a future Test Club, please contact us by email.