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Professor David Llewellyn

Professor David Llewellyn

Director of Research and Innovation

 6018

 +44 (0) 1392 726018

 College House 

 

College House, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK

Overview

David is a Professor of Clinical Epidemiology and Digital Health at the University of Exeter Medical School and the Director of Research and Impact at the Departments of Health and Community Sciences and Health and Care Professions. He is also a Fellow at the Alan Turing Institute, the national institute for data science and AI, and holds an honorary contract with Devon Partnership NHS Trust. He moved to Exeter in 2009 having received advanced training in epidemiology and data science at the University of Cambridge. He is the Director of the Deep Dementia Phenotyping (DEMON) Network, a global network to combat dementia and promote brain health using data science and AI with over 1,500 members. He co-founded the Alan Turing Institute Interest Group in Precision Dementia Medicine. He sits on the Steering Committee of the Early Detection of Neurodegeneration (EDoN) initiative and is Deputy Lead of the Clinical Hub. He sits on Alzheimer’s Research UK’s Grant Review Board and their Clinical Policy Advisory Panel. David is also the Exeter Institute for Data Science and Artificial Intelligence Clinical Theme Lead and the Turing Exeter University Clinical Lead. He is an Editor of Alzheimer's Research & Therapy, and sits on the Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) Advisory Council. He has published over 100 articles in prestigious journals such as JAMA, Alzheimer's & Dementia, JAMA Psychiatry, Neurology, and the BMJ. 

Twitter: @DrDJLlewellyn

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Research group links

Research

Publications

Key publications | Publications by category | Publications by year

Key publications


Tai XY, Veldsman M, Lyall DM, Littlejohns TJ, Langa KM, Husain M, Ranson J, Llewellyn DJ (2022). Cardiometabolic multimorbidity, genetic risk, and dementia: a prospective cohort study. Lancet Healthy Longev, 3(6), e428-e436. Abstract.  Author URL.
Ward DD, Ranson JM, Wallace LMK, Llewellyn DJ, Rockwood K (2022). Frailty, lifestyle, genetics and dementia risk. J Neurol Neurosurg Psychiatry, 93(4), 343-350. Abstract.  Author URL.
Lourida I, Hannon E, Littlejohns TJ, Langa KM, Hyppönen E, Kuzma E, Llewellyn DJ (2019). Association of Lifestyle and Genetic Risk with Incidence of Dementia. JAMA, 322(5), 430-437. Abstract.  Author URL.
Cadar D, Lassale C, Davies H, Llewellyn DJ, Batty GD, Steptoe A (2018). Individual and Area-Based Socioeconomic Factors Associated with Dementia Incidence in England: Evidence from a 12-Year Follow-up in the English Longitudinal Study of Ageing. JAMA Psychiatry, 75(7), 723-732. Abstract.  Author URL.
Kuzma E, Lourida I, Moore SF, Levine DA, Ukoumunne O, Llewellyn D (2018). Stroke and dementia risk: a systematic review and meta-analysis. Alzheimer's & Dementia: the Journal of the Alzheimer's Association, 1-11. Abstract.
Littlejohns TJ, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Fried L, Kestenbaum BR, Kuller LH, Langa KM, et al (2014). Vitamin D and the risk of dementia and Alzheimer disease. Neurology, 83(10), 920-928. Abstract.  Author URL.

Publications by category


Journal articles

Clark C, Thomas D, Llewellyn D, Ferrucci L, Bandinelli S, Campbell J (In Press). Systolic inter-arm blood pressure difference and risk of cognitive decline in the elderly: cohort study. British Journal of General Practice
1. Kuźma E, Littlejohns T, Khawaja A, Llewellyn D, Ukoumunne O, Thiem U (In Press). Visual impairment, eye diseases and dementia risk: a systematic review and meta-analysis. Journal of Alzheimer's Disease
Du R, Zhou Y, you C, Liu K, King DA, Liang Z-S, Ranson JM, Llewellyn DJ, Huang J, Zhang Z, et al (2022). Attention-deficit/hyperactivity disorder and ischemic stroke: a Mendelian randomization study. Int J Stroke Abstract.  Author URL.
Tai XY, Veldsman M, Lyall DM, Littlejohns TJ, Langa KM, Husain M, Ranson J, Llewellyn DJ (2022). Cardiometabolic multimorbidity, genetic risk, and dementia: a prospective cohort study. Lancet Healthy Longev, 3(6), e428-e436. Abstract.  Author URL.
Nihat A, Ranson JM, Harris D, McNiven K, Mok T, Rudge P, Collinge J, Llewellyn DJ, Mead S (2022). Development of prognostic models for survival and care status in sporadic Creutzfeldt-Jakob disease. Brain Commun, 4(4). Abstract.  Author URL.
Ward DD, Ranson JM, Wallace LMK, Llewellyn DJ, Rockwood K (2022). Frailty, lifestyle, genetics and dementia risk. J Neurol Neurosurg Psychiatry, 93(4), 343-350. Abstract.  Author URL.
Pham K, Mulugeta A, Zhou A, O'Brien JT, Llewellyn DJ, Hyppönen E (2022). High coffee consumption, brain volume and risk of dementia and stroke. Nutr Neurosci, 25(10), 2111-2122. Abstract.  Author URL.
Abbott RA, Rogers M, Lourida I, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore D, Hussey C, et al (2022). New horizons for caring for people with dementia in hospital: the DEMENTIA CARE pointers for service change. Age and Ageing, 51(9). Abstract.
Huang J, Liang Z-S, Pallotti S, Ranson JM, Llewellyn DJ, Zheng Z-J, King DA, Zhou Q, Zheng H, Napolioni V, et al (2022). PAGEANT: personal access to genome and analysis of natural traits. Nucleic Acids Res, 50(7). Abstract.  Author URL.
Jenkins ND, Hoogendijk EO, Armstrong JJ, Lewis NA, Ranson JM, Rijnhart JJM, Ahmed T, Ghachem A, Mullin DS, Ntanasi E, et al (2022). Trajectories of Frailty with Aging: Coordinated Analysis of Five Longitudinal Studies. Innovation in Aging, 6(2).
Navale SS, Mulugeta A, Zhou A, Llewellyn DJ, Hyppönen E (2022). Vitamin D and brain health: an observational and Mendelian randomization study. Am J Clin Nutr, 116(2), 531-540. Abstract.  Author URL.
Pham K, Mulugeta A, Zhou A, O'Brien JT, Llewellyn DJ, Hypponen E (2021). Coffee, Brain Volume and Risk of Dementia and Stroke. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 50, 188-188. Author URL.
Cadar D, Abell J, Matthews FE, Brayne C, David Batty G, Llewellyn DJ, Steptoe A (2021). Cohort Profile Update: the Harmonised Cognitive Assessment Protocol Sub-study of the English Longitudinal Study of Ageing (ELSA-HCAP). Int J Epidemiol, 50(3), 725-726i. Author URL.
Zhang N, Ranson JM, Zheng Z-J, Hannon E, Zhou Z, Kong X, Llewellyn DJ, King DA, Huang J (2021). Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort study. Sci Rep, 11(1). Abstract.  Author URL.
Siervo M, Shannon OM, Llewellyn DJ, Stephan BC, Fontana L (2021). Mediterranean diet and cognitive function: from methodology to mechanisms of action. Free Radic Biol Med, 176, 105-117. Abstract.  Author URL.
Ranson JM, Rittman T, Hayat S, Brayne C, Jessen F, Blennow K, van Duijn C, Barkhof F, Tang E, Mummery CJ, et al (2021). Modifiable risk factors for dementia and dementia risk profiling. A user manual for Brain Health Services-part 2 of 6. Alzheimers Res Ther, 13(1). Abstract.  Author URL.
James C, Ranson JM, Everson R, Llewellyn DJ (2021). Performance of Machine Learning Algorithms for Predicting Progression to Dementia in Memory Clinic Patients. JAMA Netw Open, 4(12). Abstract.  Author URL.
Lourida I, Gwernan-Jones R, Abbott R, Rogers M, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore D, et al (2020). Activity interventions to improve the experience of care in hospital for people living with dementia: a systematic review. BMC Geriatr, 20(1). Abstract.  Author URL.
Alfredsson L, Armstrong BK, Allan Butterfield D, Chowdhury R, de Gruijl FR, Feelisch M, Garland CF, Hart PH, Hoel DG, Jacobsen R, et al (2020). Insufficient sun exposure has become a real public health problem. International Journal of Environmental Research and Public Health, 17(14), 1-15. Abstract.
Ranson JM, James C, Routledge C, Everson R, Bauermeister SD, Llewellyn DJ (2020). The DEMON Network: the first UK network for deep dementia phenotyping. Alzheimer's & Dementia, 16(S10).
Gwernan-Jones R, Abbott R, Lourida I, Rogers M, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore DA, et al (2020). The experiences of hospital staff who provide care for people living with dementia: a systematic review and synthesis of qualitative studies. INTERNATIONAL JOURNAL OF OLDER PEOPLE NURSING, 15(4). Author URL.
Gwernan-Jones R, Lourida I, Abbott RA, Rogers M, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore D, et al (2020). Understanding and improving experiences of care in hospital for people living with dementia, their carers and staff: three systematic reviews. Health Services and Delivery Research, 8(43), 1-248. Abstract.
Thompson‐Coon J, Abbott RA, Lourida I, Gwernan‐Jones R, Rogers M, Cheeseman D, Moore D, Green C, Ball S, Clare L, et al (2020). Understanding and improving the experience of care for people with dementia in hospital: Developing the dementia care pointers for service change. Alzheimer's & Dementia, 16(S7).
Chouët J, Sacco G, Karras SN, Llewellyn DJ, Sánchez-Rodríguez D, Annweiler C (2020). Vitamin D and Delirium in Older Adults: a Case-Control Study in Geriatric Acute Care Unit. Frontiers in Neurology, 11 Abstract.
Brailean A, Steptoe A, Batty GD, Zaninotto P, Llewellyn DJ (2019). Are subjective memory complaints indicative of objective cognitive decline or depressive symptoms? Findings from the English Longitudinal Study of Ageing. J Psychiatr Res, 110, 143-151. Abstract.  Author URL.
Lourida I, Hannon E, Littlejohns TJ, Langa KM, Hyppönen E, Kuzma E, Llewellyn DJ (2019). Association of Lifestyle and Genetic Risk with Incidence of Dementia. JAMA, 322(5), 430-437. Abstract.  Author URL.
Le Moigno JM, Annweiler G, Karras SN, Llewellyn DJ, Riou J, Annweiler C (2019). Clinical identification of older adults with hypovitaminosis D: Feasibility, acceptability and accuracy of the ‘Vitamin D Status Diagnosticator’ in primary care. Journal of Steroid Biochemistry and Molecular Biology, 197 Abstract.
Sanchez X, Torregrossa M, Woodman T, Jones G, Llewellyn DJ (2019). Identification of Parameters That Predict Sport Climbing Performance. FRONTIERS IN PSYCHOLOGY, 10 Author URL.
Kuzma E, Lourida I, Hannon E, Littlejohns TJ, Langa KM, Hyppönen E, Llewellyn DJ (2019). O3‐05‐02: GENETIC RISK, LIFESTYLE AND DEMENTIA. Alzheimer's & Dementia, 15, p890-p890.
Ranson JM, Kuzma E, Hamilton W, Llewellyn DJ (2019). P2‐307: DECODE DEMENTIA: INITIAL DEVELOPMENT AND EXTERNAL VALIDATION OF CLINICAL PREDICTION MODELS FOR DEMENTIA IDENTIFICATION. Alzheimer's & Dementia, 15, p704-p705.
Kuzma E, Lourida I, Hannon E, Littlejohns TJ, Llewellyn DJ (2019). P2‐549: BODY MASS INDEX, GENETIC RISK AND ALL‐CAUSE DEMENTIA. Alzheimer's & Dementia, 15, p830-p831.
Lourida I, Gwernan-Jones R, Abbott RA, Rogers M, Green C, Ball S, Richards D, Hemsley A, Clare L, Llewellyn DJ, et al (2019). P3‐522: IMPROVING THE EXPERIENCE OF CARE FOR PEOPLE WITH DEMENTIA IN HOSPITAL: SYNTHESIS OF QUALITATIVE AND QUANTITATIVE EVIDENCE. Alzheimer's & Dementia, 15, p1170-p1170.
Folley S, Zhou A, Llewellyn DJ, Hyppönen E (2019). Physical Activity, APOE Genotype, and Cognitive Decline: Exploring Gene-Environment Interactions in the UK Biobank. J Alzheimers Dis, 71(3), 741-750. Abstract.  Author URL.
Ranson JM, Kuźma E, Hamilton W, Muniz-Terrera G, Langa KM, Llewellyn DJ (2019). Predictors of dementia misclassification when using brief cognitive assessments. Neurol Clin Pract, 9(2), 109-117. Abstract.  Author URL.
Evans IEM, Llewellyn DJ, Matthews FE, Woods RT, Brayne C, Clare L (2019). Social isolation, cognitive reserve, and cognition in older people with depression and anxiety. Aging and Mental Health, 23(12), 1691-1700. Abstract.
Haljas K, Amare AT, Alizadeh BZ, Hsu Y-H, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, et al (2018). Bivariate Genome-Wide Association Study of Depressive Symptoms with Type 2 Diabetes and Quantitative Glycemic Traits. Psychosom Med, 80(3), 242-251. Abstract.  Author URL.
Ranson JM, Kuźma E, Hamilton W, Lang I, Llewellyn DJ (2018). Case-finding in clinical practice: an appropriate strategy for dementia identification?. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 4, 288-296. Abstract.
Clark CE, Thomas D, Warren F, Llewellyn D, Ferrucci L, Campbell J (2018). Detecting Risks of Postural Hypotension (DROP): derivation and validation of a prediction score for primary care. BMJ Open
Zhou A, Taylor AE, Karhunen V, Zhan Y, Rovio SP, Lahti J, Sjögren P, Byberg L, Lyall DM, Auvinen J, et al (2018). Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants. Sci Rep, 8(1). Abstract.  Author URL.
Moore SF, Hamilton W, Llewellyn DJ (2018). Harnessing the power of intelligent machines to enhance primary care. Br J Gen Pract, 68(666), 6-7. Author URL.
Cadar D, Lassale C, Davies H, Llewellyn DJ, Batty GD, Steptoe A (2018). Individual and Area-Based Socioeconomic Factors Associated with Dementia Incidence in England: Evidence from a 12-Year Follow-up in the English Longitudinal Study of Ageing. JAMA Psychiatry, 75(7), 723-732. Abstract.  Author URL.
Cadar D, Lassale C, Davies H, Llewellyn DJ, Batty GD, Steptoe A (2018). Individual and area-based socioeconomic factors associated with dementia incidence in England: evidence from a 12-year follow-up in the English Longitudinal Study of Ageing (vol 75, pg 723, 2018) - Clarifications in Abstract and Key Points. JAMA Psychiatry, 75(7), 759-759.
Evans IEM, Llewellyn DJ, Matthews FE, Woods RT, Brayne C, Clare L (2018). Living alone and cognitive function in later life. Archives of Gerontology and Geriatrics
Evans IEM, Llewellyn DJ, Matthews FE, Woods RT, Brayne C, Clare L, CFAS-Wales research team (2018). Social isolation, cognitive reserve, and cognition in healthy older people. PLoS One, 13(8). Abstract.  Author URL.
Kuzma E, Lourida I, Moore SF, Levine DA, Ukoumunne O, Llewellyn D (2018). Stroke and dementia risk: a systematic review and meta-analysis. Alzheimer's & Dementia: the Journal of the Alzheimer's Association, 1-11. Abstract.
Kuźma E, Hannon E, Zhou A, Lourida I, Bethel A, Levine DA, Lunnon K, Thompson-Coon J, Hyppönen E, Llewellyn DJ, et al (2018). Which Risk Factors Causally Influence Dementia? a Systematic Review of Mendelian Randomization Studies. J Alzheimers Dis, 64(1), 181-193. Abstract.  Author URL.
Woodford J, Farrand P, Watkins ER, Lewellyn DJ (2018). ”I Don’t Believe in Leading a Life of My Own, I Lead His Life”: a Qualitative Investigation of Difficulties Experienced by Informal Caregivers of Stroke Survivors Experiencing Depressive and Anxious Symptoms. Clinical Gerontologist, 41(4), 293-307. Abstract.
Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DHR, et al (2017). An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Biol Psychiatry, 82(5), 322-329. Abstract.  Author URL.
Kuźma E, Airdrie J, Littlejohns TJ, Lourida I, Thompson-Coon J, Lang IA, Scrobotovici M, Thacker EL, Fitzpatrick A, Kuller LH, et al (2017). Coronary Artery Bypass Graft Surgery and Dementia Risk in the Cardiovascular Health Study. Alzheimer Disease and Associated Disorders, 31(2), 120-127. Abstract.
Hunt HA, Van Kampen S, Takwoingi Y, Llewellyn DJ, Pearson M, Hyde CJ (2017). The comparative diagnostic accuracy of the Mini Mental State Examination (MMSE) and the General Practitioner assessment of Cognition (GPCOG) for identifying dementia in primary care: a systematic review protocol. Diagnostic and Prognostic Research, 1, 1-6.
Dickens CM, Bollen J, Trick L, Llewellyn D (2017). The effects of acute inflammation on cognitive functioning and emotional processing in humans: a systematic review of experimental studies. Journal of Psychosomatic Research
Maddock J, Zhou A, Cavadino A, Kuźma E, Bao Y, Smart MC, Saum K-U, Schöttker B, Engmann J, Kjærgaard M, et al (2017). Vitamin D and cognitive function: a Mendelian randomisation study. Sci Rep, 7(1). Abstract.  Author URL.
Farina N, Llewellyn DJ, Isaac MGEKN, Tabet N (2017). Vitamin E for Alzheimer’s dementia and mild cognitive impairment (Review). Cochrane Database of Systematic Reviews, 2017(4). Abstract.
Ranson JM, Kuzma E, Hamilton W, Llewellyn DJ (2017). [P1–498]: MISCLASSIFICATION OF DEMENTIA BY BRIEF COGNITIVE ASSESSMENTS IN THE AGING, DEMOGRAPHICS AND MEMORY STUDY. Alzheimer's & Dementia, 13(7S_Part_9), p481-p482.
Lourida I, Kuzma E, Ranson JM, Hunt H, Talens‐Bou J, Rogers M, Thompson‐Coon J, Llewellyn DJ (2017). [P2–094]: DEVELOPMENT OF a DEMENTIA META‐EVIDENCE DATABASE (EMANATE). Alzheimer's & Dementia, 13(7S_Part_13), p642-p643.
Ukoumunne OC, 1. Farrand P, Woodford J, Llewellyn D, Anderson M, Venkatasubramanian S, Adlam A, Dickens C (2016). Behavioural activation written self-help to improve mood, wellbeing and quality of life in people with dementia supported by informal carers (PROMOTE): study protocol for a single-arm feasibility study. Pilot and Feasibility Studies
van Schoor NM, Comijs HC, Llewellyn DJ, Lips P (2016). Cross-sectional and longitudinal associations between serum 25-hydroxyvitamin D and cognitive functioning. Int Psychogeriatr, 28(5), 759-768. Abstract.  Author URL.
Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, et al (2016). GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Mol Psychiatry, 21(2), 189-197. Abstract.  Author URL.
Kuzma E, Airdrie J, Littlejohns TJ, Lourida I, Thompson-Coon J, Lang IA, Scrobotovici M, Thacker E, Fitzpatrick AL, Kuller LH, et al (2016). O2‐09‐05: Coronary Artery Bypass Graft Surgery and Dementia Risk in the Cardiovascular Health Study. Alzheimer's & Dementia, 12(7S_Part_5), p248-p249.
Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, Nalls MA, Tanaka T, Hek K, Fornage M, et al (2016). Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychol Med, 46(8), 1613-1623. Abstract.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Kuźma E, Llewellyn DJ (2016). Vitamin D and Dementia. J Prev Alzheimers Dis, 3(1), 43-52. Abstract.  Author URL.
Kuźma E, Soni M, Littlejohns TJ, Ranson JM, van Schoor NM, Deeg DJH, Comijs H, Chaves PHM, Kestenbaum BR, Kuller LH, et al (2016). Vitamin D and Memory Decline: Two Population-Based Prospective Studies. J Alzheimers Dis, 50(4), 1099-1108. Abstract.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Kestenbaum BR, Kuller LH, Langa KM, et al (2016). Vitamin D and Risk of Neuroimaging Abnormalities. PLoS One, 11(5). Abstract.  Author URL.
Annweiler C, Dursun E, Féron F, Gezen-Ak D, Kalueff AV, Littlejohns T, Llewellyn DJ, Millet P, Scott T, Tucker KL, et al (2015). 'Vitamin D and cognition in older adults': Updated international recommendations. Journal of Internal Medicine, 277(1), 45-57. Abstract.
Ranson JM, Kuzma E, Langa KM, Llewellyn DJ (2015). P3‐192: Primary care‐relevant predictors of dementia status in the aging, demographics and memory study. Alzheimer's & Dementia, 11(7S_Part_15), p705-p706.
Lourida I, Thompson-Coon J, Dickens CM, Soni M, Kuźma E, Kos K, Llewellyn DJ (2015). Parathyroid hormone, cognitive function and dementia: a systematic review. PLoS One, 10(5). Abstract.  Author URL.
Jones G, Llewellyn D, Johnson MI (2015). Previous injury as a risk factor for reinjury in rock climbing: a secondary analysis of data from a retrospective cross-sectional cohort survey of active rock climbers. BMJ Open Sport Exerc Med, 1(1). Abstract.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Cherubini A, Ferrucci L, Lang IA, Langa KM, Melzer D, Llewellyn DJ (2015). Serum leptin and risk of cognitive decline in elderly italians. J Alzheimers Dis, 44(4), 1231-1239. Abstract.  Author URL.
Dutta A, Henley W, Robine J-M, Llewellyn D, Langa KM, Wallace RB, Melzer D (2014). Aging children of long-lived parents experience slower cognitive decline. Alzheimers Dement, 10(5 Suppl), S315-S322. Abstract.  Author URL.
Hubbard RE, Goodwin VA, Llewellyn DJ, Warmoth K, Lang IA (2014). Frailty, financial resources and subjective well-being in later life. Archives of Gerontology and Geriatrics, 58(3), 364-369. Abstract.
Kuźma E, Llewellyn DJ, Langa KM, Wallace RB, Lang IA (2014). History of alcohol use disorders and risk of severe cognitive impairment: a 19-year prospective cohort study. Am J Geriatr Psychiatry, 22(10), 1047-1054. Abstract.  Author URL.
Evans IEM, Kuzma E, Lang IA, Adlam AR, Llewellyn DJ (2014). P1‐345: WHICH BRIEF ASSESSMENT MEASURES FOR DEMENTIA ARE CURRENTLY RECOMMENDED FOR USE IN PRIMARY CARE? a SYSTEMATIC REVIEW. Alzheimer's & Dementia, 10(4S_Part_11).
Lourida I, Soni M, Kuzma E, Thompson‐Coon J, Dickens C, Kos K, Llewellyn DJ (2014). P2‐309: DO PARATHYROID HORMONE LEVELS PLAY a ROLE IN DEMENTIA? a SYSTEMATIC REVIEW. Alzheimer's & Dementia, 10(4S_Part_15), p591-p592.
Littlejohns TJ, Kos K, Henley WE, Cherubini A, Ferrucci L, Lang IA, Langa KM, Melzer D, Llewellyn DJ (2014). SERUM LEPTIN AND RISK OF COGNITIVE DECLINE IN ELDERLY ITALIANS: a PROSPECTIVE COHORT STUDY. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 68, A4-A4. Author URL.
Woodford J, Farrand P, Watkins ER, Richards DA, Llewellyn DJ (2014). Supported cognitive-behavioural self-help versus treatment-as-usual for depressed informal carers of stroke survivors (CEDArS): study protocol for a feasibility randomized controlled trial. Trials, 157 Abstract.  Author URL.
Littlejohns TJ, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Fried L, Kestenbaum BR, Kuller LH, Langa KM, et al (2014). Vitamin D and the risk of dementia and Alzheimer disease. Neurology, 83(10), 920-928. Abstract.  Author URL.
Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, et al (2013). A genome-wide association study of depressive symptoms. Biol Psychiatry, 73(7), 667-678. Abstract.  Author URL.
Annweiler C, Llewellyn DJ, Beauchet O (2013). Low serum vitamin D concentrations in Alzheimer's disease: a systematic review and meta-analysis. J Alzheimers Dis, 33(3), 659-674. Abstract.  Author URL.
Lourida I, Soni M, Thompson-Coon J, Purandare N, Lang IA, Ukoumunne OC, Llewellyn DJ (2013). Mediterranean diet, cognitive function, and dementia: a systematic review. Epidemiology, 24(4), 479-489. Abstract.
Annweiler C, Montero-Odasso M, Llewellyn DJ, Richard-Devantoy S, Duque G, Beauchet O (2013). Meta-analysis of memory and executive dysfunctions in relation to vitamin D. J Alzheimers Dis, 37(1), 147-171. Abstract.  Author URL.
Lourida I, Thompson‐Coon J, Dickens C, Soni M, Kos K, Llewellyn D (2013). P3–198: a systematic review of the relationship between parathyroid hormone levels and cognitive function and dementia. Alzheimer's & Dementia, 9(4S_Part_16), p627-p627.
Antoniou EE, Dutta A, Langa KM, Melzer D, Llewellyn D (2013). Personality profile of the children of long-lived parents. J Gerontol B Psychol Sci Soc Sci, 68(5), 730-738. Abstract.  Author URL.
Woodford J, Farrand P, Richards D, Llewellyn DJ (2013). Psychological treatments for common mental health problems experienced by informal carers of adults with chronic physical health conditions (Protocol). Syst Rev, 2 Abstract.  Author URL.
Pludowski P, Holick MF, Pilz S, Wagner CL, Hollis BW, Grant WB, Shoenfeld Y, Lerchbaum E, Llewellyn DJ, Kienreich K, et al (2013). Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-A review of recent evidence. Autoimmunity Reviews, 12(10), 976-989. Abstract.
Brouwer-Brolsma EM, Bischoff-Ferrari HA, Bouillon R, Feskens EJM, Gallagher CJ, Hypponen E, Llewellyn DJ, Stoecklin E, Dierkes J, Kies AK, et al (2013). Vitamin D: Do we get enough?: a discussion between vitamin D experts in order to make a step towards the harmonisation of dietary reference intakes for vitamin D across Europe. Osteoporosis International, 24(5), 1567-1577. Abstract.
Brouwer-Brolsma EM, Bischoff-Ferrari HA, Bouillon R, Feskens EJM, Gallagher CJ, Hypponen E, Llewellyn DJ, Stoecklin E, Dierkes J, Kies AK, et al (2013). Vitamin D: do we get enough? a discussion between vitamin D experts in order to make a step towards the harmonisation of dietary reference intakes for vitamin D across Europe. Osteoporos Int, 24(5), 1567-1577. Abstract.  Author URL.
Melzer D, Harries L, Llewellyn DJ, Bandinelli S, Guralnik JM, Ferrucci L (2012). GENE EXPRESSION ASSOCIATIONS WITH MMSE SCORES: PHAGOCYTOSIS OF CNS BETA AMYLIOD?. GERONTOLOGIST, 52, 453-453. Author URL.
Pilling LC, Harries LW, Powell J, Llewellyn DJ, Ferrucci L, Melzer D (2012). Genomics and successful aging: grounds for renewed optimism?. J Gerontol a Biol Sci Med Sci, 67(5), 511-519. Abstract.  Author URL.
Harries LW, Bradley-Smith RM, Llewellyn DJ, Pilling LC, Fellows A, Henley W, Hernandez D, Guralnik JM, Bandinelli S, Singleton A, et al (2012). Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults. Rejuvenation Res, 15(4), 395-404. Abstract.  Author URL.
Stephan BCM, Hunter S, Harris D, Llewellyn DJ, Siervo M, Matthews FE, Brayne C (2012). The neuropathological profile of mild cognitive impairment (MCI): a systematic review. Molecular Psychiatry, 17(11), 1056-1076. Abstract.
Soni M, Kos K, Lang IA, Jones K, Melzer D, Llewellyn DJ (2012). Vitamin D and cognitive function. Scand J Clin Lab Invest Suppl, 243, 79-82. Abstract.  Author URL.
Balion C, Griffith LE, Strifler L, Henderson M, Patterson C, Heckman G, Llewellyn DJ, Raina P (2012). Vitamin D, cognition, and dementia: a systematic review and meta-analysis. Neurology, 79(13), 1397-1405. Abstract.  Author URL.
Fisher GG, Franks MM, Plassman BL, Brown SL, Potter GG, Llewellyn D, Rogers MAM, Langa KM (2011). Caring for individuals with dementia and cognitive impairment, not dementia: Findings from the aging, demographics, and memory study. Journal of the American Geriatrics Society, 59(3), 488-494. Abstract.
Lang IA, Llewellyn DJ, Hubbard RE, Langa KM, Melzer D (2011). Income and the midlife peak in common mental disorder prevalence. Psychol Med, 41(7), 1365-1372. Abstract.  Author URL.
Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Potter GG, Langa KM (2011). Neuropsychiatric symptoms and the risk of institutionalization and death: the aging, demographics, and memory study. J Am Geriatr Soc, 59(3), 473-481. Abstract.  Author URL.
Dutta A, Henley W, Lang I, Llewellyn D, Guralnik J, Wallace RB, Melzer D (2011). Predictors of extraordinary survival in the Iowa established populations for epidemiologic study of the elderly: cohort follow-up to "extinction". J Am Geriatr Soc, 59(6), 963-971. Abstract.  Author URL.
Balion CM, Griffith LE, Strifler L, Henderson M, Patterson C, Heckman G, Llewellyn DJ, Raina PS (2011). Vitamin D and cognition: a meta-analysis. CLINICAL BIOCHEMISTRY, 44(13), 1166-1166. Author URL.
Llewellyn DJ, Lang IA, Langa KM, Melzer D (2011). Vitamin D and cognitive impairment in the elderly U.S. population. Journals of Gerontology - Series a Biological Sciences and Medical Sciences, 66 A(1), 59-65. Abstract.
Llewellyn DJ, Lang IA, Langa KM, Melzer D (2011). Vitamin D and cognitive impairment in the elderly U.S. population. J Gerontol a Biol Sci Med Sci, 66(1), 59-65. Abstract.  Author URL.
Dickens AP, Lang IA, Langa KM, Kos K, Llewellyn DJ (2011). Vitamin D, cognitive dysfunction and dementia in older adults. CNS Drugs, 25(8), 629-639. Abstract.  Author URL.
Zivin K, Llewellyn DJ, Lang IA, Vijan S, Kabeto MU, Miller EM, Langa KM (2010). Depression among older adults in the United States and England. Am J Geriatr Psychiatry, 18(11), 1036-1044. Abstract.  Author URL.
Hubbard RE, Lang IA, Llewellyn DJ, Rockwood K (2010). Frailty, body mass index, and abdominal obesity in older people. Journals of Gerontology - Series a Biological Sciences and Medical Sciences, 65 A(4), 377-381. Abstract.
Cluett C, Brayne C, Clarke R, Evans G, Matthews F, Rubinsztein DC, Huppert F, Llewellyn DJ, Rice N, Henley W, et al (2010). Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people. Neurobiol Aging, 31(9), 1563-1568. Abstract.  Author URL.
Sanchez X, Boschker MSJ, Llewellyn DJ (2010). Pre-performance psychological states and performance in an elite climbing competition. Scand J Med Sci Sports, 20(2), 356-363. Abstract.  Author URL.
Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Potter GG, Langa KM (2010). Prevalence of neuropsychiatric symptoms and their association with functional limitations in older adults in the United States: the aging, demographics, and memory study. J Am Geriatr Soc, 58(2), 330-337. Abstract.  Author URL.
Llewellyn DJ, Langa KM, Friedland RP, Lang IA (2010). Serum Albumin Concentration and Cognitive Impairment. CURRENT ALZHEIMER RESEARCH, 7(1), 91-96. Author URL.
Llewellyn DJ, Langa KM, Friedland RP, Lang IA (2010). Serum albumin concentration and cognitive impairment. Curr Alzheimer Res, 7(1), 91-96. Abstract.  Author URL.
Llewellyn DJ, Lang IA, Matthews FE, Plassman BL, Rogers MA, Morgenstern LB, Fisher GG, Kabeto MU, Langa KM (2010). Vascular health, diabetes, APOE and dementia: the Aging, Demographics, and Memory Study. Alzheimers Res Ther, 2(3). Abstract.  Author URL.
Llewellyn DJ, Lang IA, Langa KM, Muniz-Terrera G, Phillips CL, Cherubini A, Ferrucci L, Melzer D (2010). Vitamin D and risk of cognitive decline in elderly persons. Arch Intern Med, 170(13), 1135-1141. Abstract.  Author URL.
Langa KM, Llewellyn DJ, Lang IA, Weir DR, Wallace RB, Kabeto MU, Huppert FA (2009). Cognitive health among older adults in the United States and in England. BMC Geriatr, 9 Abstract.  Author URL.
Potter GG, Plassman BL, Burke JR, Kabeto MU, Langa KM, Llewellyn DJ, Rogers MAM, Steffens DC (2009). Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites. Alzheimers Dement, 5(6), 445-453. Abstract.  Author URL.
Llewellyn DJ, Lang LA, Langa KM, Naughton F, Matthews FE (2009). Exposure to secondhand smoke and cognitive impairment in non-smokers: National cross sectional study with cotinine measurement. BMJ (Online), 338(7695). Abstract.
Llewellyn DJ, Matthews FE (2009). Increasing levels of semantic verbal fluency in elderly English adults. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn, 16(4), 433-445. Abstract.  Author URL.
Lang IA, Hubbard RE, Andrew MK, Llewellyn DJ, Melzer D, Rockwood K (2009). Neighborhood deprivation, individual socioeconomic status, and frailty in older adults. J Am Geriatr Soc, 57(10), 1776-1780. Abstract.  Author URL.
Rogers MAM, Plassman BL, Kabeto M, Fisher GG, McArdle JJ, Llewellyn DJ, Potter GG, Langa KM (2009). Parental education and late-life dementia in the United States. J Geriatr Psychiatry Neurol, 22(1), 71-80. Abstract.  Author URL.
Llewellyn DJ, Langa KM, Lang IA (2009). Serum 25-hydroxyvitamin D concentration and cognitive impairment. J Geriatr Psychiatry Neurol, 22(3), 188-195. Abstract.  Author URL.
Llewellyn DJ, Lang IA, Langa KM, Huppert FA (2008). Cognitive function and psychological well-being: findings from a population-based cohort. Age Ageing, 37(6), 685-689. Abstract.  Author URL.
Llewellyn DJ, Lang IA, Xie J, Huppert FA, Melzer D, Langa KM (2008). Framingham Stroke Risk Profile and poor cognitive function: a population-based study. BMC Neurol, 8 Abstract.  Author URL.
Lang IA, Llewellyn DJ, Langa KM, Wallace RB, Huppert FA, Melzer D (2008). Neighborhood deprivation, individual socioeconomic status, and cognitive function in older people: analyses from the English Longitudinal Study of Ageing. J Am Geriatr Soc, 56(2), 191-198. Abstract.  Author URL.
Lang IA, Llewellyn DJ, Langa KM, Wallace RB, Melzer D (2008). Neighbourhood deprivation and incident mobility disability in older adults. Age Ageing, 37(4), 403-410. Abstract.  Author URL.
Lang IA, Llewellyn DJ, Alexander K, Melzer D (2008). Obesity, physical function, and mortality in older adults. J Am Geriatr Soc, 56(8), 1474-1478. Abstract.  Author URL.
Llewellyn DJ, Sanchez X, Asghar A, Jones G (2008). Self-efficacy, risk taking and performance in rock climbing. Personality and Individual Differences, 45(1), 75-81. Abstract.
Jones G, Asghar A, Llewellyn DJ (2008). The epidemiology of rock-climbing injuries. Br J Sports Med, 42(9), 773-778. Abstract.  Author URL.
Llewellyn DJ (2008). The psychology of risk taking: toward the integration of psychometric and neuropsychological paradigms. Am J Psychol, 121(3), 363-376. Abstract.  Author URL.

Conferences

Jordan AN, Aizawa K, Gooding KM, Llewellyn D, Casanova F, Mawson DM, Gates PE, Adingupu DD, Elyas S, Hope S, et al (2022). Arterial haemodynamic parameters linked to arterial pulsatility, excess wave propagation and cognitive function. European Society of Hypertension. 17th - 20th Jun 2022. Abstract.
Ellingson JM, Border RC, Lessem JM, Llewellyn DJ, Kuzma E, Keller MC (2020). Do modifiable risk factors moderate the effect of APOE on cognitive decline?.  Author URL.
Ranson J, Lourida I, Hannon E, littlejohns T, Ballard C, langa K, hypponen E, Kuzma E, Llewellyn D (2020). Genetic risk, education and incidence of dementia. Alzheimer’s Association International Conference. 27th - 31st Jul 2020.
Ranson JM, Lourida I, Hannon E, Littlejohns TJ, Ballard C, Langa KM, Hyppönen E, Kuzma E, Llewellyn DJ (2020). Genetic risk, education and incidence of dementia.
Coon JT, Abbott R, Lourida I, Gwernan-Jones R, Rogers M, Cheeseman D, Moore D, Green C, Ball S, Clare L, et al (2020). IMPROVING THE EXPERIENCE OF CARE FOR PEOPLE WITH DEMENTIA IN HOSPITAL: DEVELOPING THE DEMENTIA CARE POINTERS FOR SERVICE CHANGE.  Author URL.
Ranson J, Lourida ILIANNA, Hannon E, littlejohns T, Ballard C, langa K, hypponen E, Kuzma E, Llewellyn D (2020). Stroke, genetic risk and incidence of dementia. Alzheimer's Association International Conference. 27th - 31st Jul 2020.
MaWhinney K, Tounkara MD, Evans K, Startup E, Ehlert A, Covey E, Westra J, Blades NJ, Dhamoon MS, Gonzalez HM, et al (2019). Cardiovascular Health and Cognitive Decline in Older Adults: the Cardiovascular Health Study.  Author URL.
Tounkara MD, MaWhinney K, Evans K, Startup E, Ehlert A, Covey E, Westra J, Blades NJ, Dhamoon MS, Gonzalez HM, et al (2019). Seven-Year Changes in Cardiovascular Health in Older Adults: the Cardiovascular Health Study.  Author URL.
Cadar D, Hackett RA, Mischie M, Llewellyn DJ, Batty GD, Steptoe A (2017). Association of physical activity as a distinctive feature of clustering of lifestyle behaviours with dementia risk: evidence from the English Longitudinal Study of Ageing.  Author URL.
Kuzma E, Hannon E, Zhou A, Lourida I, Bethel A, Levine D, Lunnon K, Thompson‐Coon J, Hyppönen E, Llewellyn DJ, et al (2017). [P3–529]: a SYSTEMATIC REVIEW OF MENDELIAN RANDOMIZATION STUDIES INVESTIGATING CAUSAL ASSOCIATIONS BETWEEN RISK FACTORS AND DEMENTIA.
Kuzma E, Littlejohns TJ, Soni M, Chaves PHM, Kestenbaum BR, Kuller LH, Lopez OL, Becker JT, Langa KM, Henley WE, et al (2015). O2‐03‐01: Vitamin D and decline in global cognition and memory in the cardiovascular health study.
Littlejohns TJ, Kos K, Henley WE, Annweiler C, Beauchet O, Chaves PHM, Lang IA, Kuller LH, Langa KM, Lopez OL, et al (2015). O2‐03‐02: Vitamin D and the risk of developing neuroimaging abnormalities.
Lourida I, Kuzma E, Henley WE, Thompson-Coon J, Dickens CM, Langa KM, Llewellyn DJ (2015). P1‐255: Lifestyle, treatment, and cognitive decline in elderly diabetics.
Llewellyn D, Lang I, Langa K, Henley W (2013). O2–13–02: Assessing long‐term postoperative cognitive decline using conventional and quasi‐experimental approaches: a Monte Carlo simulation study.
Littlejohns T, Soni M, Annweiler C, Chaves P, Fried L, Kestenbaum B, Lang I, Langa K, Lopez O, Kos K, et al (2013). P4–394: Vitamin D and incident Alzheimer's disease in the Cardiovascular Health Cognition Study.
Goodwin VA, Hubbard RE, Llewellyn D, Lang I (2012). CHANGES IN HEALTH STATUS AMONGST THE OLDEST-OLD: TRENDS OVER TWO DECADES IN THE ENGLISH POPULATION AGED 85+.  Author URL.
Hubbard RE, Lang IA, Goodwin V, Llewellyn DJ (2012). CHANGES IN MEDICATION PRESCRIBING FOR THE OLDEST OLD.  Author URL.
Woodford J, Farrand P, Richards DA, Llewellyn D (2012). Coping in informal carers of stroke survivors: a comparison of coping strategies used by depressed and non-depressed informal carers.  Author URL.
Hubbard RE, Lang IA, Goodwin V, Llewellyn DJ (2012). FRAILTY AND OBESITY IN LATER LIFE.  Author URL.
Goodwin VA, Hubbard RE, Llewellyn DJ, Lang IA (2012). HEALTH, WEALTH AND WELL-BEING IN OLDER PEOPLE.  Author URL.
Lang IA, Goodwin V, Hubbard R, Llewellyn DJ (2012). HEALTHY BEHAVIOURS IN MIDDLE AGE AND LONG-TERM CONSEQUENCES FOR MORTALITY, PHYSICAL AND COGNITIVE FUNCTION, AND MENTAL HEALTH.  Author URL.
Lang IA, Goodwin V, Hubbard RE, Llewellyn D (2012). HEALTHY BEHAVIOURS IN MIDDLE AGE: LONG-TERM CONSEQUENCES FOR FUNCTIONING AND MORTALITY.  Author URL.
Lang I, Hubbard R, Goodwin V, Llewellyn DJ (2011). DOES FRAILTY EXPLAIN "AGE-RELATED" DECLINES IN WELLBEING IN LATER LIFE?.  Author URL.
Llewellyn DJ, Melzer D, Lang I, Langa KM, Kos K (2011). THE EMERGING ROLE OF ADIPOKINES IN COGNITIVE DECLINE AND DEMENTIA.  Author URL.
Llewellyn DJ, Kos K, Langa KM, Ferrucci L, Henley WE, Lang IA, Clarke R, Chiu H, Li J, Cherubini A, et al (2010). P4‐056: Association of Serum Leptin Levels with Cognitive Decline is Dependent on Body Mass Index.
Llewellyn DJ, Lang IA, Langa KM, Xie J, Huppert FA (2009). Stroke risk profile and reduced cognitive function: Findings from the English Longitudinal Study of Ageing.  Author URL.
Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Langa KM (2009). THE QUANTITY OF ACTIVE HELP AND SUPERVISION PROVIDED TO OLDER ADULTS WITH NEUROPSYCHIATRIC SYMPTOMS: THE AGING, DEMOGRAPHICS, AND MEMORY STUDY (ADAMS).  Author URL.
Llewellyn DJ, Langa KM, Lang I (2009). VITAMIN D DEFICIENCY AND COGNITIVE DYSFUNCTION IN OLDER ADULTS.  Author URL.
Llewellyn DJ, Sanchez X (2008). Individual differences and risk taking in rock climbing.  Abstract.
Llewellyn DJ, Lang I, Lang K, Huppert F (2008). Psychological well-being is associated with higher levels of cognitive function.  Author URL.
Lang IA, Llewellyn DJ, Melzer D (2008). The importance of income to the "midlife crisis": Findings from a cross-section of 88,000 adults.  Author URL.

Publications by year


In Press

Nihat A, Ranson J, Harris D, McNiven K, Rudge P, Collinge J, Llewellyn D, Mead SH (In Press). Development of Prognostic Models for Survival and Care Status in Sporadic Creutzfeldt-Jakob disease. med Rxiv
Clark C, Thomas D, Llewellyn D, Ferrucci L, Bandinelli S, Campbell J (In Press). Systolic inter-arm blood pressure difference and risk of cognitive decline in the elderly: cohort study. British Journal of General Practice
1. Kuźma E, Littlejohns T, Khawaja A, Llewellyn D, Ukoumunne O, Thiem U (In Press). Visual impairment, eye diseases and dementia risk: a systematic review and meta-analysis. Journal of Alzheimer's Disease

2022

Jordan AN, Aizawa K, Gooding KM, Llewellyn D, Casanova F, Mawson DM, Gates PE, Adingupu DD, Elyas S, Hope S, et al (2022). Arterial haemodynamic parameters linked to arterial pulsatility, excess wave propagation and cognitive function. European Society of Hypertension. 17th - 20th Jun 2022. Abstract.
Du R, Zhou Y, you C, Liu K, King DA, Liang Z-S, Ranson JM, Llewellyn DJ, Huang J, Zhang Z, et al (2022). Attention-deficit/hyperactivity disorder and ischemic stroke: a Mendelian randomization study. Int J Stroke Abstract.  Author URL.
Tai XY, Veldsman M, Lyall DM, Littlejohns TJ, Langa KM, Husain M, Ranson J, Llewellyn DJ (2022). Cardiometabolic multimorbidity, genetic risk, and dementia: a prospective cohort study. Lancet Healthy Longev, 3(6), e428-e436. Abstract.  Author URL.
Nihat A, Ranson JM, Harris D, McNiven K, Mok T, Rudge P, Collinge J, Llewellyn DJ, Mead S (2022). Development of prognostic models for survival and care status in sporadic Creutzfeldt-Jakob disease. Brain Commun, 4(4). Abstract.  Author URL.
Ward DD, Ranson JM, Wallace LMK, Llewellyn DJ, Rockwood K (2022). Frailty, lifestyle, genetics and dementia risk. J Neurol Neurosurg Psychiatry, 93(4), 343-350. Abstract.  Author URL.
Pham K, Mulugeta A, Zhou A, O'Brien JT, Llewellyn DJ, Hyppönen E (2022). High coffee consumption, brain volume and risk of dementia and stroke. Nutr Neurosci, 25(10), 2111-2122. Abstract.  Author URL.
Abbott RA, Rogers M, Lourida I, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore D, Hussey C, et al (2022). New horizons for caring for people with dementia in hospital: the DEMENTIA CARE pointers for service change. Age and Ageing, 51(9). Abstract.
Huang J, Liang Z-S, Pallotti S, Ranson JM, Llewellyn DJ, Zheng Z-J, King DA, Zhou Q, Zheng H, Napolioni V, et al (2022). PAGEANT: personal access to genome and analysis of natural traits. Nucleic Acids Res, 50(7). Abstract.  Author URL.
Jenkins ND, Hoogendijk EO, Armstrong JJ, Lewis NA, Ranson JM, Rijnhart JJM, Ahmed T, Ghachem A, Mullin DS, Ntanasi E, et al (2022). Trajectories of Frailty with Aging: Coordinated Analysis of Five Longitudinal Studies. Innovation in Aging, 6(2).
Navale SS, Mulugeta A, Zhou A, Llewellyn DJ, Hyppönen E (2022). Vitamin D and brain health: an observational and Mendelian randomization study. Am J Clin Nutr, 116(2), 531-540. Abstract.  Author URL.

2021

Pham K, Mulugeta A, Zhou A, O'Brien JT, Llewellyn DJ, Hypponen E (2021). Coffee, Brain Volume and Risk of Dementia and Stroke. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 50, 188-188. Author URL.
Cadar D, Abell J, Matthews FE, Brayne C, David Batty G, Llewellyn DJ, Steptoe A (2021). Cohort Profile Update: the Harmonised Cognitive Assessment Protocol Sub-study of the English Longitudinal Study of Ageing (ELSA-HCAP). Int J Epidemiol, 50(3), 725-726i. Author URL.
Zhang N, Ranson J, Zheng Z-J, Hannon E, Zhou Z, Kong X, Llewellyn D, King D, Huang J (2021). Interaction Between Genetic Predisposition, Smoking, and Dementia Risk: a Population-based Cohort Study.
Zhang N, Ranson JM, Zheng Z-J, Hannon E, Zhou Z, Kong X, Llewellyn DJ, King DA, Huang J (2021). Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort study. Sci Rep, 11(1). Abstract.  Author URL.
Guest F (2021). Machine Learning for Classification and Clustering of Dementia Data.  Abstract.
Siervo M, Shannon OM, Llewellyn DJ, Stephan BC, Fontana L (2021). Mediterranean diet and cognitive function: from methodology to mechanisms of action. Free Radic Biol Med, 176, 105-117. Abstract.  Author URL.
Ranson JM, Rittman T, Hayat S, Brayne C, Jessen F, Blennow K, van Duijn C, Barkhof F, Tang E, Mummery CJ, et al (2021). Modifiable risk factors for dementia and dementia risk profiling. A user manual for Brain Health Services-part 2 of 6. Alzheimers Res Ther, 13(1). Abstract.  Author URL.
Huang J, Liang Z-S, Pallotti S, Ranson JM, Llewellyn DJ, Zheng Z-J, King DA, Zhou Q, Zheng H, Napolioni V, et al (2021). PAGEANT: Personal Access to Genome and Analysis of Natural Traits.
James C, Ranson JM, Everson R, Llewellyn DJ (2021). Performance of Machine Learning Algorithms for Predicting Progression to Dementia in Memory Clinic Patients. JAMA Netw Open, 4(12). Abstract.  Author URL.

2020

Lourida I, Gwernan-Jones R, Abbott R, Rogers M, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore D, et al (2020). Activity interventions to improve the experience of care in hospital for people living with dementia: a systematic review. BMC Geriatr, 20(1). Abstract.  Author URL.
Ranson J (2020). Development and validation of clinical prediction models for dementia identification in non-specialist settings.  Abstract.
Ellingson JM, Border RC, Lessem JM, Llewellyn DJ, Kuzma E, Keller MC (2020). Do modifiable risk factors moderate the effect of APOE on cognitive decline?.  Author URL.
Ranson J, Lourida I, Hannon E, littlejohns T, Ballard C, langa K, hypponen E, Kuzma E, Llewellyn D (2020). Genetic risk, education and incidence of dementia. Alzheimer’s Association International Conference. 27th - 31st Jul 2020.
Ranson JM, Lourida I, Hannon E, Littlejohns TJ, Ballard C, Langa KM, Hyppönen E, Kuzma E, Llewellyn DJ (2020). Genetic risk, education and incidence of dementia.
Coon JT, Abbott R, Lourida I, Gwernan-Jones R, Rogers M, Cheeseman D, Moore D, Green C, Ball S, Clare L, et al (2020). IMPROVING THE EXPERIENCE OF CARE FOR PEOPLE WITH DEMENTIA IN HOSPITAL: DEVELOPING THE DEMENTIA CARE POINTERS FOR SERVICE CHANGE.  Author URL.
Alfredsson L, Armstrong BK, Allan Butterfield D, Chowdhury R, de Gruijl FR, Feelisch M, Garland CF, Hart PH, Hoel DG, Jacobsen R, et al (2020). Insufficient sun exposure has become a real public health problem. International Journal of Environmental Research and Public Health, 17(14), 1-15. Abstract.
Ranson J, Lourida ILIANNA, Hannon E, littlejohns T, Ballard C, langa K, hypponen E, Kuzma E, Llewellyn D (2020). Stroke, genetic risk and incidence of dementia. Alzheimer's Association International Conference. 27th - 31st Jul 2020.
Ranson JM, James C, Routledge C, Everson R, Bauermeister SD, Llewellyn DJ (2020). The DEMON Network: the first UK network for deep dementia phenotyping. Alzheimer's & Dementia, 16(S10).
Gwernan-Jones R, Abbott R, Lourida I, Rogers M, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore DA, et al (2020). The experiences of hospital staff who provide care for people living with dementia: a systematic review and synthesis of qualitative studies. INTERNATIONAL JOURNAL OF OLDER PEOPLE NURSING, 15(4). Author URL.
Gwernan-Jones R, Lourida I, Abbott RA, Rogers M, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore D, et al (2020). Understanding and improving experiences of care in hospital for people living with dementia, their carers and staff: three systematic reviews. Health Services and Delivery Research, 8(43), 1-248. Abstract.
Thompson‐Coon J, Abbott RA, Lourida I, Gwernan‐Jones R, Rogers M, Cheeseman D, Moore D, Green C, Ball S, Clare L, et al (2020). Understanding and improving the experience of care for people with dementia in hospital: Developing the dementia care pointers for service change. Alzheimer's & Dementia, 16(S7).
Chouët J, Sacco G, Karras SN, Llewellyn DJ, Sánchez-Rodríguez D, Annweiler C (2020). Vitamin D and Delirium in Older Adults: a Case-Control Study in Geriatric Acute Care Unit. Frontiers in Neurology, 11 Abstract.

2019

Brailean A, Steptoe A, Batty GD, Zaninotto P, Llewellyn DJ (2019). Are subjective memory complaints indicative of objective cognitive decline or depressive symptoms? Findings from the English Longitudinal Study of Ageing. J Psychiatr Res, 110, 143-151. Abstract.  Author URL.
Lourida I, Hannon E, Littlejohns TJ, Langa KM, Hyppönen E, Kuzma E, Llewellyn DJ (2019). Association of Lifestyle and Genetic Risk with Incidence of Dementia. JAMA, 322(5), 430-437. Abstract.  Author URL.
MaWhinney K, Tounkara MD, Evans K, Startup E, Ehlert A, Covey E, Westra J, Blades NJ, Dhamoon MS, Gonzalez HM, et al (2019). Cardiovascular Health and Cognitive Decline in Older Adults: the Cardiovascular Health Study.  Author URL.
Le Moigno JM, Annweiler G, Karras SN, Llewellyn DJ, Riou J, Annweiler C (2019). Clinical identification of older adults with hypovitaminosis D: Feasibility, acceptability and accuracy of the ‘Vitamin D Status Diagnosticator’ in primary care. Journal of Steroid Biochemistry and Molecular Biology, 197 Abstract.
Sanchez X, Torregrossa M, Woodman T, Jones G, Llewellyn DJ (2019). Identification of Parameters That Predict Sport Climbing Performance. FRONTIERS IN PSYCHOLOGY, 10 Author URL.
Hunt H (2019). Improving the accuracy of brief cognitive assessments when used as part of the process for identifying dementia in general practice.  Abstract.
Kuzma E, Lourida I, Hannon E, Littlejohns TJ, Langa KM, Hyppönen E, Llewellyn DJ (2019). O3‐05‐02: GENETIC RISK, LIFESTYLE AND DEMENTIA. Alzheimer's & Dementia, 15, p890-p890.
Ranson JM, Kuzma E, Hamilton W, Llewellyn DJ (2019). P2‐307: DECODE DEMENTIA: INITIAL DEVELOPMENT AND EXTERNAL VALIDATION OF CLINICAL PREDICTION MODELS FOR DEMENTIA IDENTIFICATION. Alzheimer's & Dementia, 15, p704-p705.
Kuzma E, Lourida I, Hannon E, Littlejohns TJ, Llewellyn DJ (2019). P2‐549: BODY MASS INDEX, GENETIC RISK AND ALL‐CAUSE DEMENTIA. Alzheimer's & Dementia, 15, p830-p831.
Lourida I, Gwernan-Jones R, Abbott RA, Rogers M, Green C, Ball S, Richards D, Hemsley A, Clare L, Llewellyn DJ, et al (2019). P3‐522: IMPROVING THE EXPERIENCE OF CARE FOR PEOPLE WITH DEMENTIA IN HOSPITAL: SYNTHESIS OF QUALITATIVE AND QUANTITATIVE EVIDENCE. Alzheimer's & Dementia, 15, p1170-p1170.
Folley S, Zhou A, Llewellyn DJ, Hyppönen E (2019). Physical Activity, APOE Genotype, and Cognitive Decline: Exploring Gene-Environment Interactions in the UK Biobank. J Alzheimers Dis, 71(3), 741-750. Abstract.  Author URL.
Ranson JM, Kuźma E, Hamilton W, Muniz-Terrera G, Langa KM, Llewellyn DJ (2019). Predictors of dementia misclassification when using brief cognitive assessments. Neurol Clin Pract, 9(2), 109-117. Abstract.  Author URL.
Tounkara MD, MaWhinney K, Evans K, Startup E, Ehlert A, Covey E, Westra J, Blades NJ, Dhamoon MS, Gonzalez HM, et al (2019). Seven-Year Changes in Cardiovascular Health in Older Adults: the Cardiovascular Health Study.  Author URL.
Evans I (2019). Social connections, cognitive reserve, and cognitive function in later life.  Abstract.
Evans IEM, Llewellyn DJ, Matthews FE, Woods RT, Brayne C, Clare L (2019). Social isolation, cognitive reserve, and cognition in older people with depression and anxiety. Aging and Mental Health, 23(12), 1691-1700. Abstract.

2018

Haljas K, Amare AT, Alizadeh BZ, Hsu Y-H, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, et al (2018). Bivariate Genome-Wide Association Study of Depressive Symptoms with Type 2 Diabetes and Quantitative Glycemic Traits. Psychosom Med, 80(3), 242-251. Abstract.  Author URL.
Ranson JM, Kuźma E, Hamilton W, Lang I, Llewellyn DJ (2018). Case-finding in clinical practice: an appropriate strategy for dementia identification?. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 4, 288-296. Abstract.
Clark CE, Thomas D, Warren F, Llewellyn D, Ferrucci L, Campbell J (2018). Detecting Risks of Postural Hypotension (DROP): derivation and validation of a prediction score for primary care. BMJ Open
Zhou A, Taylor AE, Karhunen V, Zhan Y, Rovio SP, Lahti J, Sjögren P, Byberg L, Lyall DM, Auvinen J, et al (2018). Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants. Sci Rep, 8(1). Abstract.  Author URL.
Moore SF, Hamilton W, Llewellyn DJ (2018). Harnessing the power of intelligent machines to enhance primary care. Br J Gen Pract, 68(666), 6-7. Author URL.
Cadar D, Lassale C, Davies H, Llewellyn DJ, Batty GD, Steptoe A (2018). Individual and Area-Based Socioeconomic Factors Associated with Dementia Incidence in England: Evidence from a 12-Year Follow-up in the English Longitudinal Study of Ageing. JAMA Psychiatry, 75(7), 723-732. Abstract.  Author URL.
Cadar D, Lassale C, Davies H, Llewellyn DJ, Batty GD, Steptoe A (2018). Individual and area-based socioeconomic factors associated with dementia incidence in England: evidence from a 12-year follow-up in the English Longitudinal Study of Ageing (vol 75, pg 723, 2018) - Clarifications in Abstract and Key Points. JAMA Psychiatry, 75(7), 759-759.
Evans IEM, Llewellyn DJ, Matthews FE, Woods RT, Brayne C, Clare L (2018). Living alone and cognitive function in later life. Archives of Gerontology and Geriatrics
Evans IEM, Llewellyn DJ, Matthews FE, Woods RT, Brayne C, Clare L, CFAS-Wales research team (2018). Social isolation, cognitive reserve, and cognition in healthy older people. PLoS One, 13(8). Abstract.  Author URL.
Kuzma E, Lourida I, Moore SF, Levine DA, Ukoumunne O, Llewellyn D (2018). Stroke and dementia risk: a systematic review and meta-analysis. Alzheimer's & Dementia: the Journal of the Alzheimer's Association, 1-11. Abstract.
Kuźma E, Hannon E, Zhou A, Lourida I, Bethel A, Levine DA, Lunnon K, Thompson-Coon J, Hyppönen E, Llewellyn DJ, et al (2018). Which Risk Factors Causally Influence Dementia? a Systematic Review of Mendelian Randomization Studies. J Alzheimers Dis, 64(1), 181-193. Abstract.  Author URL.
Woodford J, Farrand P, Watkins ER, Lewellyn DJ (2018). ”I Don’t Believe in Leading a Life of My Own, I Lead His Life”: a Qualitative Investigation of Difficulties Experienced by Informal Caregivers of Stroke Survivors Experiencing Depressive and Anxious Symptoms. Clinical Gerontologist, 41(4), 293-307. Abstract.

2017

Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DHR, et al (2017). An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Biol Psychiatry, 82(5), 322-329. Abstract.  Author URL.
Cadar D, Hackett RA, Mischie M, Llewellyn DJ, Batty GD, Steptoe A (2017). Association of physical activity as a distinctive feature of clustering of lifestyle behaviours with dementia risk: evidence from the English Longitudinal Study of Ageing.  Author URL.
Kuźma E, Airdrie J, Littlejohns TJ, Lourida I, Thompson-Coon J, Lang IA, Scrobotovici M, Thacker EL, Fitzpatrick A, Kuller LH, et al (2017). Coronary Artery Bypass Graft Surgery and Dementia Risk in the Cardiovascular Health Study. Alzheimer Disease and Associated Disorders, 31(2), 120-127. Abstract.
Hunt HA, Van Kampen S, Takwoingi Y, Llewellyn DJ, Pearson M, Hyde CJ (2017). The comparative diagnostic accuracy of the Mini Mental State Examination (MMSE) and the General Practitioner assessment of Cognition (GPCOG) for identifying dementia in primary care: a systematic review protocol. Diagnostic and Prognostic Research, 1, 1-6.
Dickens CM, Bollen J, Trick L, Llewellyn D (2017). The effects of acute inflammation on cognitive functioning and emotional processing in humans: a systematic review of experimental studies. Journal of Psychosomatic Research
Maddock J, Zhou A, Cavadino A, Kuźma E, Bao Y, Smart MC, Saum K-U, Schöttker B, Engmann J, Kjærgaard M, et al (2017). Vitamin D and cognitive function: a Mendelian randomisation study. Sci Rep, 7(1). Abstract.  Author URL.
Farina N, Llewellyn DJ, Isaac MGEKN, Tabet N (2017). Vitamin E for Alzheimer’s dementia and mild cognitive impairment (Review). Cochrane Database of Systematic Reviews, 2017(4). Abstract.
Ranson JM, Kuzma E, Hamilton W, Llewellyn DJ (2017). [P1–498]: MISCLASSIFICATION OF DEMENTIA BY BRIEF COGNITIVE ASSESSMENTS IN THE AGING, DEMOGRAPHICS AND MEMORY STUDY. Alzheimer's & Dementia, 13(7S_Part_9), p481-p482.
Lourida I, Kuzma E, Ranson JM, Hunt H, Talens‐Bou J, Rogers M, Thompson‐Coon J, Llewellyn DJ (2017). [P2–094]: DEVELOPMENT OF a DEMENTIA META‐EVIDENCE DATABASE (EMANATE). Alzheimer's & Dementia, 13(7S_Part_13), p642-p643.
Kuzma E, Hannon E, Zhou A, Lourida I, Bethel A, Levine D, Lunnon K, Thompson‐Coon J, Hyppönen E, Llewellyn DJ, et al (2017). [P3–529]: a SYSTEMATIC REVIEW OF MENDELIAN RANDOMIZATION STUDIES INVESTIGATING CAUSAL ASSOCIATIONS BETWEEN RISK FACTORS AND DEMENTIA.

2016

Ukoumunne OC, 1. Farrand P, Woodford J, Llewellyn D, Anderson M, Venkatasubramanian S, Adlam A, Dickens C (2016). Behavioural activation written self-help to improve mood, wellbeing and quality of life in people with dementia supported by informal carers (PROMOTE): study protocol for a single-arm feasibility study. Pilot and Feasibility Studies
van Schoor NM, Comijs HC, Llewellyn DJ, Lips P (2016). Cross-sectional and longitudinal associations between serum 25-hydroxyvitamin D and cognitive functioning. Int Psychogeriatr, 28(5), 759-768. Abstract.  Author URL.
Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, et al (2016). GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Mol Psychiatry, 21(2), 189-197. Abstract.  Author URL.
Kuzma E, Airdrie J, Littlejohns TJ, Lourida I, Thompson-Coon J, Lang IA, Scrobotovici M, Thacker E, Fitzpatrick AL, Kuller LH, et al (2016). O2‐09‐05: Coronary Artery Bypass Graft Surgery and Dementia Risk in the Cardiovascular Health Study. Alzheimer's & Dementia, 12(7S_Part_5), p248-p249.
Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, Nalls MA, Tanaka T, Hek K, Fornage M, et al (2016). Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychol Med, 46(8), 1613-1623. Abstract.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Kuźma E, Llewellyn DJ (2016). Vitamin D and Dementia. J Prev Alzheimers Dis, 3(1), 43-52. Abstract.  Author URL.
Kuźma E, Soni M, Littlejohns TJ, Ranson JM, van Schoor NM, Deeg DJH, Comijs H, Chaves PHM, Kestenbaum BR, Kuller LH, et al (2016). Vitamin D and Memory Decline: Two Population-Based Prospective Studies. J Alzheimers Dis, 50(4), 1099-1108. Abstract.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Kestenbaum BR, Kuller LH, Langa KM, et al (2016). Vitamin D and Risk of Neuroimaging Abnormalities. PLoS One, 11(5). Abstract.  Author URL.

2015

Annweiler C, Dursun E, Féron F, Gezen-Ak D, Kalueff AV, Littlejohns T, Llewellyn DJ, Millet P, Scott T, Tucker KL, et al (2015). 'Vitamin D and cognition in older adults': Updated international recommendations. Journal of Internal Medicine, 277(1), 45-57. Abstract.
Kuzma E, Littlejohns TJ, Soni M, Chaves PHM, Kestenbaum BR, Kuller LH, Lopez OL, Becker JT, Langa KM, Henley WE, et al (2015). O2‐03‐01: Vitamin D and decline in global cognition and memory in the cardiovascular health study.
Littlejohns TJ, Kos K, Henley WE, Annweiler C, Beauchet O, Chaves PHM, Lang IA, Kuller LH, Langa KM, Lopez OL, et al (2015). O2‐03‐02: Vitamin D and the risk of developing neuroimaging abnormalities.
Lourida I, Kuzma E, Henley WE, Thompson-Coon J, Dickens CM, Langa KM, Llewellyn DJ (2015). P1‐255: Lifestyle, treatment, and cognitive decline in elderly diabetics.
Ranson JM, Kuzma E, Langa KM, Llewellyn DJ (2015). P3‐192: Primary care‐relevant predictors of dementia status in the aging, demographics and memory study. Alzheimer's & Dementia, 11(7S_Part_15), p705-p706.
Lourida I, Thompson-Coon J, Dickens CM, Soni M, Kuźma E, Kos K, Llewellyn DJ (2015). Parathyroid hormone, cognitive function and dementia: a systematic review. PLoS One, 10(5). Abstract.  Author URL.
Jones G, Llewellyn D, Johnson MI (2015). Previous injury as a risk factor for reinjury in rock climbing: a secondary analysis of data from a retrospective cross-sectional cohort survey of active rock climbers. BMJ Open Sport Exerc Med, 1(1). Abstract.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Cherubini A, Ferrucci L, Lang IA, Langa KM, Melzer D, Llewellyn DJ (2015). Serum leptin and risk of cognitive decline in elderly italians. J Alzheimers Dis, 44(4), 1231-1239. Abstract.  Author URL.

2014

Dutta A, Henley W, Robine J-M, Llewellyn D, Langa KM, Wallace RB, Melzer D (2014). Aging children of long-lived parents experience slower cognitive decline. Alzheimers Dement, 10(5 Suppl), S315-S322. Abstract.  Author URL.
Ranson J (2014). Development and validation of a dementia screening tool for use in primary care.  Abstract.
Hubbard RE, Goodwin VA, Llewellyn DJ, Warmoth K, Lang IA (2014). Frailty, financial resources and subjective well-being in later life. Archives of Gerontology and Geriatrics, 58(3), 364-369. Abstract.
Kuźma E, Llewellyn DJ, Langa KM, Wallace RB, Lang IA (2014). History of alcohol use disorders and risk of severe cognitive impairment: a 19-year prospective cohort study. Am J Geriatr Psychiatry, 22(10), 1047-1054. Abstract.  Author URL.
Evans IEM, Kuzma E, Lang IA, Adlam AR, Llewellyn DJ (2014). P1‐345: WHICH BRIEF ASSESSMENT MEASURES FOR DEMENTIA ARE CURRENTLY RECOMMENDED FOR USE IN PRIMARY CARE? a SYSTEMATIC REVIEW. Alzheimer's & Dementia, 10(4S_Part_11).
Lourida I, Soni M, Kuzma E, Thompson‐Coon J, Dickens C, Kos K, Llewellyn DJ (2014). P2‐309: DO PARATHYROID HORMONE LEVELS PLAY a ROLE IN DEMENTIA? a SYSTEMATIC REVIEW. Alzheimer's & Dementia, 10(4S_Part_15), p591-p592.
Littlejohns TJ, Kos K, Henley WE, Cherubini A, Ferrucci L, Lang IA, Langa KM, Melzer D, Llewellyn DJ (2014). SERUM LEPTIN AND RISK OF COGNITIVE DECLINE IN ELDERLY ITALIANS: a PROSPECTIVE COHORT STUDY. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 68, A4-A4. Author URL.
Woodford J, Farrand P, Watkins ER, Richards DA, Llewellyn DJ (2014). Supported cognitive-behavioural self-help versus treatment-as-usual for depressed informal carers of stroke survivors (CEDArS): study protocol for a feasibility randomized controlled trial. Trials, 157 Abstract.  Author URL.
Littlejohns TJ, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Fried L, Kestenbaum BR, Kuller LH, Langa KM, et al (2014). Vitamin D and the risk of dementia and Alzheimer disease. Neurology, 83(10), 920-928. Abstract.  Author URL.

2013

Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, et al (2013). A genome-wide association study of depressive symptoms. Biol Psychiatry, 73(7), 667-678. Abstract.  Author URL.
Annweiler C, Llewellyn DJ, Beauchet O (2013). Low serum vitamin D concentrations in Alzheimer's disease: a systematic review and meta-analysis. J Alzheimers Dis, 33(3), 659-674. Abstract.  Author URL.
Lourida I, Soni M, Thompson-Coon J, Purandare N, Lang IA, Ukoumunne OC, Llewellyn DJ (2013). Mediterranean diet, cognitive function, and dementia: a systematic review. Epidemiology, 24(4), 479-489. Abstract.
Annweiler C, Montero-Odasso M, Llewellyn DJ, Richard-Devantoy S, Duque G, Beauchet O (2013). Meta-analysis of memory and executive dysfunctions in relation to vitamin D. J Alzheimers Dis, 37(1), 147-171. Abstract.  Author URL.
Llewellyn D, Lang I, Langa K, Henley W (2013). O2–13–02: Assessing long‐term postoperative cognitive decline using conventional and quasi‐experimental approaches: a Monte Carlo simulation study.
Lourida I, Thompson‐Coon J, Dickens C, Soni M, Kos K, Llewellyn D (2013). P3–198: a systematic review of the relationship between parathyroid hormone levels and cognitive function and dementia. Alzheimer's & Dementia, 9(4S_Part_16), p627-p627.
Littlejohns T, Soni M, Annweiler C, Chaves P, Fried L, Kestenbaum B, Lang I, Langa K, Lopez O, Kos K, et al (2013). P4–394: Vitamin D and incident Alzheimer's disease in the Cardiovascular Health Cognition Study.
Antoniou EE, Dutta A, Langa KM, Melzer D, Llewellyn D (2013). Personality profile of the children of long-lived parents. J Gerontol B Psychol Sci Soc Sci, 68(5), 730-738. Abstract.  Author URL.
Woodford J, Farrand P, Richards D, Llewellyn DJ (2013). Psychological treatments for common mental health problems experienced by informal carers of adults with chronic physical health conditions (Protocol). Syst Rev, 2 Abstract.  Author URL.
Pludowski P, Holick MF, Pilz S, Wagner CL, Hollis BW, Grant WB, Shoenfeld Y, Lerchbaum E, Llewellyn DJ, Kienreich K, et al (2013). Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-A review of recent evidence. Autoimmunity Reviews, 12(10), 976-989. Abstract.
Brouwer-Brolsma EM, Bischoff-Ferrari HA, Bouillon R, Feskens EJM, Gallagher CJ, Hypponen E, Llewellyn DJ, Stoecklin E, Dierkes J, Kies AK, et al (2013). Vitamin D: Do we get enough?: a discussion between vitamin D experts in order to make a step towards the harmonisation of dietary reference intakes for vitamin D across Europe. Osteoporosis International, 24(5), 1567-1577. Abstract.
Brouwer-Brolsma EM, Bischoff-Ferrari HA, Bouillon R, Feskens EJM, Gallagher CJ, Hypponen E, Llewellyn DJ, Stoecklin E, Dierkes J, Kies AK, et al (2013). Vitamin D: do we get enough? a discussion between vitamin D experts in order to make a step towards the harmonisation of dietary reference intakes for vitamin D across Europe. Osteoporos Int, 24(5), 1567-1577. Abstract.  Author URL.

2012

Goodwin VA, Hubbard RE, Llewellyn D, Lang I (2012). CHANGES IN HEALTH STATUS AMONGST THE OLDEST-OLD: TRENDS OVER TWO DECADES IN THE ENGLISH POPULATION AGED 85+.  Author URL.
Hubbard RE, Lang IA, Goodwin V, Llewellyn DJ (2012). CHANGES IN MEDICATION PRESCRIBING FOR THE OLDEST OLD.  Author URL.
Woodford J, Farrand P, Richards DA, Llewellyn D (2012). Coping in informal carers of stroke survivors: a comparison of coping strategies used by depressed and non-depressed informal carers.  Author URL.
Hubbard RE, Lang IA, Goodwin V, Llewellyn DJ (2012). FRAILTY AND OBESITY IN LATER LIFE.  Author URL.
Melzer D, Harries L, Llewellyn DJ, Bandinelli S, Guralnik JM, Ferrucci L (2012). GENE EXPRESSION ASSOCIATIONS WITH MMSE SCORES: PHAGOCYTOSIS OF CNS BETA AMYLIOD?. GERONTOLOGIST, 52, 453-453. Author URL.
Pilling LC, Harries LW, Powell J, Llewellyn DJ, Ferrucci L, Melzer D (2012). Genomics and successful aging: grounds for renewed optimism?. J Gerontol a Biol Sci Med Sci, 67(5), 511-519. Abstract.  Author URL.
Goodwin VA, Hubbard RE, Llewellyn DJ, Lang IA (2012). HEALTH, WEALTH AND WELL-BEING IN OLDER PEOPLE.  Author URL.
Lang IA, Goodwin V, Hubbard R, Llewellyn DJ (2012). HEALTHY BEHAVIOURS IN MIDDLE AGE AND LONG-TERM CONSEQUENCES FOR MORTALITY, PHYSICAL AND COGNITIVE FUNCTION, AND MENTAL HEALTH.  Author URL.
Lang IA, Goodwin V, Hubbard RE, Llewellyn D (2012). HEALTHY BEHAVIOURS IN MIDDLE AGE: LONG-TERM CONSEQUENCES FOR FUNCTIONING AND MORTALITY.  Author URL.
Harries LW, Bradley-Smith RM, Llewellyn DJ, Pilling LC, Fellows A, Henley W, Hernandez D, Guralnik JM, Bandinelli S, Singleton A, et al (2012). Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults. Rejuvenation Res, 15(4), 395-404. Abstract.  Author URL.
Stephan BCM, Hunter S, Harris D, Llewellyn DJ, Siervo M, Matthews FE, Brayne C (2012). The neuropathological profile of mild cognitive impairment (MCI): a systematic review. Molecular Psychiatry, 17(11), 1056-1076. Abstract.
Soni M, Kos K, Lang IA, Jones K, Melzer D, Llewellyn DJ (2012). Vitamin D and cognitive function. Scand J Clin Lab Invest Suppl, 243, 79-82. Abstract.  Author URL.
Balion C, Griffith LE, Strifler L, Henderson M, Patterson C, Heckman G, Llewellyn DJ, Raina P (2012). Vitamin D, cognition, and dementia: a systematic review and meta-analysis. Neurology, 79(13), 1397-1405. Abstract.  Author URL.

2011

Fisher GG, Franks MM, Plassman BL, Brown SL, Potter GG, Llewellyn D, Rogers MAM, Langa KM (2011). Caring for individuals with dementia and cognitive impairment, not dementia: Findings from the aging, demographics, and memory study. Journal of the American Geriatrics Society, 59(3), 488-494. Abstract.
Lang I, Hubbard R, Goodwin V, Llewellyn DJ (2011). DOES FRAILTY EXPLAIN "AGE-RELATED" DECLINES IN WELLBEING IN LATER LIFE?.  Author URL.
Lang IA, Llewellyn DJ, Hubbard RE, Langa KM, Melzer D (2011). Income and the midlife peak in common mental disorder prevalence. Psychol Med, 41(7), 1365-1372. Abstract.  Author URL.
Llewellyn DJ, Langa KM, Lang IA, Melzer D (2011). Investigating factors of decline in cognitive function or dementia: Reply. Archives of Internal Medicine, 171(3).
Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Potter GG, Langa KM (2011). Neuropsychiatric symptoms and the risk of institutionalization and death: the aging, demographics, and memory study. J Am Geriatr Soc, 59(3), 473-481. Abstract.  Author URL.
Dutta A, Henley W, Lang I, Llewellyn D, Guralnik J, Wallace RB, Melzer D (2011). Predictors of extraordinary survival in the Iowa established populations for epidemiologic study of the elderly: cohort follow-up to "extinction". J Am Geriatr Soc, 59(6), 963-971. Abstract.  Author URL.
Llewellyn DJ, Melzer D, Lang I, Langa KM, Kos K (2011). THE EMERGING ROLE OF ADIPOKINES IN COGNITIVE DECLINE AND DEMENTIA.  Author URL.
Balion CM, Griffith LE, Strifler L, Henderson M, Patterson C, Heckman G, Llewellyn DJ, Raina PS (2011). Vitamin D and cognition: a meta-analysis. CLINICAL BIOCHEMISTRY, 44(13), 1166-1166. Author URL.
Llewellyn DJ, Lang IA, Langa KM, Melzer D (2011). Vitamin D and cognitive impairment in the elderly U.S. population. Journals of Gerontology - Series a Biological Sciences and Medical Sciences, 66 A(1), 59-65. Abstract.
Llewellyn DJ, Lang IA, Langa KM, Melzer D (2011). Vitamin D and cognitive impairment in the elderly U.S. population. J Gerontol a Biol Sci Med Sci, 66(1), 59-65. Abstract.  Author URL.
Dickens AP, Lang IA, Langa KM, Kos K, Llewellyn DJ (2011). Vitamin D, cognitive dysfunction and dementia in older adults. CNS Drugs, 25(8), 629-639. Abstract.  Author URL.

2010

Zivin K, Llewellyn DJ, Lang IA, Vijan S, Kabeto MU, Miller EM, Langa KM (2010). Depression among older adults in the United States and England. Am J Geriatr Psychiatry, 18(11), 1036-1044. Abstract.  Author URL.
Hubbard RE, Lang IA, Llewellyn DJ, Rockwood K (2010). Frailty, body mass index, and abdominal obesity in older people. Journals of Gerontology - Series a Biological Sciences and Medical Sciences, 65 A(4), 377-381. Abstract.
Llewellyn DJ, Kos K, Langa KM, Ferrucci L, Henley WE, Lang IA, Clarke R, Chiu H, Li J, Cherubini A, et al (2010). P4‐056: Association of Serum Leptin Levels with Cognitive Decline is Dependent on Body Mass Index.
Cluett C, Brayne C, Clarke R, Evans G, Matthews F, Rubinsztein DC, Huppert F, Llewellyn DJ, Rice N, Henley W, et al (2010). Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people. Neurobiol Aging, 31(9), 1563-1568. Abstract.  Author URL.
Sanchez X, Boschker MSJ, Llewellyn DJ (2010). Pre-performance psychological states and performance in an elite climbing competition. Scand J Med Sci Sports, 20(2), 356-363. Abstract.  Author URL.
Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Potter GG, Langa KM (2010). Prevalence of neuropsychiatric symptoms and their association with functional limitations in older adults in the United States: the aging, demographics, and memory study. J Am Geriatr Soc, 58(2), 330-337. Abstract.  Author URL.
Llewellyn DJ, Langa KM, Friedland RP, Lang IA (2010). Serum Albumin Concentration and Cognitive Impairment. CURRENT ALZHEIMER RESEARCH, 7(1), 91-96. Author URL.
Llewellyn DJ, Langa KM, Friedland RP, Lang IA (2010). Serum albumin concentration and cognitive impairment. Curr Alzheimer Res, 7(1), 91-96. Abstract.  Author URL.
Llewellyn DJ, Lang IA, Matthews FE, Plassman BL, Rogers MA, Morgenstern LB, Fisher GG, Kabeto MU, Langa KM (2010). Vascular health, diabetes, APOE and dementia: the Aging, Demographics, and Memory Study. Alzheimers Res Ther, 2(3). Abstract.  Author URL.
Llewellyn DJ, Lang IA, Langa KM, Muniz-Terrera G, Phillips CL, Cherubini A, Ferrucci L, Melzer D (2010). Vitamin D and risk of cognitive decline in elderly persons. Arch Intern Med, 170(13), 1135-1141. Abstract.  Author URL.

2009

Langa KM, Llewellyn DJ, Lang IA, Weir DR, Wallace RB, Kabeto MU, Huppert FA (2009). Cognitive health among older adults in the United States and in England. BMC Geriatr, 9 Abstract.  Author URL.
Potter GG, Plassman BL, Burke JR, Kabeto MU, Langa KM, Llewellyn DJ, Rogers MAM, Steffens DC (2009). Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites. Alzheimers Dement, 5(6), 445-453. Abstract.  Author URL.
Llewellyn DJ, Lang LA, Langa KM, Naughton F, Matthews FE (2009). Exposure to secondhand smoke and cognitive impairment in non-smokers: National cross sectional study with cotinine measurement. BMJ (Online), 338(7695). Abstract.
Llewellyn DJ, Matthews FE (2009). Increasing levels of semantic verbal fluency in elderly English adults. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn, 16(4), 433-445. Abstract.  Author URL.
Lang IA, Hubbard RE, Andrew MK, Llewellyn DJ, Melzer D, Rockwood K (2009). Neighborhood deprivation, individual socioeconomic status, and frailty in older adults. J Am Geriatr Soc, 57(10), 1776-1780. Abstract.  Author URL.
Rogers MAM, Plassman BL, Kabeto M, Fisher GG, McArdle JJ, Llewellyn DJ, Potter GG, Langa KM (2009). Parental education and late-life dementia in the United States. J Geriatr Psychiatry Neurol, 22(1), 71-80. Abstract.  Author URL.
Llewellyn DJ, Langa KM, Lang IA (2009). Serum 25-hydroxyvitamin D concentration and cognitive impairment. J Geriatr Psychiatry Neurol, 22(3), 188-195. Abstract.  Author URL.
Llewellyn DJ, Lang IA, Langa KM, Xie J, Huppert FA (2009). Stroke risk profile and reduced cognitive function: Findings from the English Longitudinal Study of Ageing.  Author URL.
Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Langa KM (2009). THE QUANTITY OF ACTIVE HELP AND SUPERVISION PROVIDED TO OLDER ADULTS WITH NEUROPSYCHIATRIC SYMPTOMS: THE AGING, DEMOGRAPHICS, AND MEMORY STUDY (ADAMS).  Author URL.
Llewellyn DJ, Langa KM, Lang I (2009). VITAMIN D DEFICIENCY AND COGNITIVE DYSFUNCTION IN OLDER ADULTS.  Author URL.

2008

Llewellyn DJ, Naughton F (2008). Antipsychotic-induced weight gain in patients with schizophrenia. JAMA, 299(16), 1898-1899. Author URL.
Llewellyn DJ, Lang IA, Langa KM, Huppert FA (2008). Cognitive function and psychological well-being: findings from a population-based cohort. Age Ageing, 37(6), 685-689. Abstract.  Author URL.
Llewellyn DJ, Lang IA, Xie J, Huppert FA, Melzer D, Langa KM (2008). Framingham Stroke Risk Profile and poor cognitive function: a population-based study. BMC Neurol, 8 Abstract.  Author URL.
Llewellyn DJ, Sanchez X (2008). Individual differences and risk taking in rock climbing.  Abstract.
Lang IA, Llewellyn DJ, Langa KM, Wallace RB, Huppert FA, Melzer D (2008). Neighborhood deprivation, individual socioeconomic status, and cognitive function in older people: analyses from the English Longitudinal Study of Ageing. J Am Geriatr Soc, 56(2), 191-198. Abstract.  Author URL.
Lang IA, Llewellyn DJ, Langa KM, Wallace RB, Melzer D (2008). Neighbourhood deprivation and incident mobility disability in older adults. Age Ageing, 37(4), 403-410. Abstract.  Author URL.
Lang IA, Llewellyn DJ, Alexander K, Melzer D (2008). Obesity, physical function, and mortality in older adults. J Am Geriatr Soc, 56(8), 1474-1478. Abstract.  Author URL.
Llewellyn DJ, Lang I, Lang K, Huppert F (2008). Psychological well-being is associated with higher levels of cognitive function.  Author URL.
Llewellyn DJ, Sanchez X, Asghar A, Jones G (2008). Self-efficacy, risk taking and performance in rock climbing. Personality and Individual Differences, 45(1), 75-81. Abstract.
Jones G, Asghar A, Llewellyn DJ (2008). The epidemiology of rock-climbing injuries. Br J Sports Med, 42(9), 773-778. Abstract.  Author URL.
Lang IA, Llewellyn DJ, Melzer D (2008). The importance of income to the "midlife crisis": Findings from a cross-section of 88,000 adults.  Author URL.
Llewellyn DJ (2008). The psychology of risk taking: toward the integration of psychometric and neuropsychological paradigms. Am J Psychol, 121(3), 363-376. Abstract.  Author URL.

David_Llewellyn Details from cache as at 2022-10-07 12:55:58

Refresh publications

External Engagement and Impact

Media Coverage

Selected: 

New York Times (2019) https://www.nytimes.com/2019/07/16/well/mind/healthy-lifestyle-may-reduce-dementia-risk.html

Time magazine (2019) https://time.com/5625778/alzheimers-genetic-risk-prevention/

BBC (2019) https://www.bbc.co.uk/news/health-48963215

New Scientist (2019) https://institutions.newscientist.com/article/2209798-healthy-living-lowers-chances-of-dementia-even-if-genetic-risk-is-high/

Guardian (2019) https://www.theguardian.com/society/2019/jul/14/healthy-lifestyle-may-cut-risk-of-dementia-regardless-of-genes

LA Times (2019) https://www.latimes.com/science/story/2019-07-15/healthy-living-alzheimer-risk

The Times (2019) https://www.thetimes.co.uk/article/healthy-living-can-beat-dementia-genes-0w9vv03t0

Telegraph (2019) https://www.telegraph.co.uk/science/2019/07/14/bad-dementia-genes-can-overcome-healthy-living-study-finds/

CNN (2019) https://edition.cnn.com/2019/07/14/health/dementia-risk-lifestyle-study/index.html

Times of India (2019) https://timesofindia.indiatimes.com/home/science/healthy-lifestyle-can-cut-dementia-risk-by-32/articleshow/70221514.cms

Houston Chronicle (2019) https://www.houstonchronicle.com/news/science/article/A-healthy-lifestyle-may-offset-genetic-risk-for-14094580.php

NBC News (2019) https://www.nbcnews.com/health/aging/can-alzheimer-s-be-stopped-five-lifestyle-behaviors-are-key-n1029441

New York Post (2019) https://nypost.com/2019/07/15/how-to-reduce-your-odds-of-getting-alzheimers/

Scientific American (2019) https://www.scientificamerican.com/article/alzheimers-meeting-lifestyle-factors-are-the-best-and-only-bet-now-for-reducing-dementia-risk/

Guardian (2018) https://www.theguardian.com/science/2018/aug/31/suffering-stroke-can-double-risk-of-dementia-study-finds

The Times (2018) https://www.thetimes.co.uk/article/strokes-may-double-risk-of-dementia-gc3jt095s

Forbes (2017) https://www.forbes.com/sites/alicegwalton/2017/01/06/can-a-diet-really-protect-the-brain/#8c4a8dd6361c

Express (2017) https://www.express.co.uk/life-style/health/884885/dementia-symptoms-vitamin-d-supplements

Express (2016) https://www.express.co.uk/life-style/health/702922/Eat-way-smarter-brain  

Guardian (2015) https://www.theguardian.com/society/2015/jan/07/healthy-ageing-diet-myths-busted

Forbes (2015) https://www.forbes.com/sites/alicegwalton/2015/05/07/healthier-diet-healthier-aging-brain/?ref=altdnt#11b16c355a51

New York Times (2014) https://well.blogs.nytimes.com/2014/08/14/vitamin-d-tied-to-alzheimers-risk/

Time (2014) http://time.com/3089339/study-research-vitamin-d-deficiency-dementia-alzheimers/

New Scientist (2014) https://www.newscientist.com/article/dn26022-lack-of-vitamin-d-more-than-doubles-risk-of-dementia/

Independent (2014) http://www.independent.co.uk/life-style/health-and-families/health-news/low-levels-of-vitamin-d-can-double-dementia-risk-9652389.html

BBC (2014) http://www.bbc.co.uk/news/health-28674158

The Times (2014) https://www.thetimes.co.uk/article/lack-of-vitamin-d-could-double-risk-of-dementia-dhr9hsnkt7x

Fox News (2014) http://www.foxnews.com/health/2014/08/07/vitamin-d-deficiency-linked-to-increased-dementia-risk.html

Forbes (2014) https://www.forbes.com/sites/robertglatter/2014/08/07/dementia-risk-and-vitamin-d-levels-is-there-a-connection/#6302c77e1888

The Telegraph (2014) http://www.telegraph.co.uk/news/health/elder/11017445/Study-sunshine-could-help-to-stave-off-dementia.html

CBS News (2014) https://www.cbsnews.com/news/low-vitamin-d-level-could-double-alzheimers-risk-study-finds/

Mirror (2014) http://www.mirror.co.uk/news/uk-news/alzheimers-risk-doubles-lack-vitamin-4004664

Washington Post (2014) https://www.washingtonpost.com/national/health-science/researchers-say-vitamin-d-deficiency-raises-alzheimers-risk/2014/08/06/ed278fde-1da1-11e4-82f9-2cd6fa8da5c4_story.html?utm_term=.74fa1c427ad7

ITV News (2014) http://www.itv.com/news/westcountry/update/2014-08-06/lack-of-vitamin-d-could-increase-risk-of-dementia/

Voice of America (2014) https://www.voanews.com/a/vitimin-d-may-help-avert-alzheimers-disease-dementia/1973271.html

Guardian (2014) https://www.theguardian.com/science/neurophilosophy/2014/sep/22/the-neuroprotective-lifestyle

Fox News (2013) http://www.foxnews.com/health/2013/12/18/ways-to-improve-your-memory.html

New York Times (2009) http://www.nytimes.com/2009/02/24/health/research/24aging.html

NHS Choices (2009) https://www.nhs.uk/news/neurology/vitamin-d-keeps-you-sharp/

BBC (2009) http://news.bbc.co.uk/1/hi/health/7845703.stm

NHS Choices (2009) https://www.nhs.uk/news/neurology/passive-smoke-and-dementia/

The Telegraph (2009) http://www.telegraph.co.uk/news/health/news/4601880/Second-hand-smoke-can-increase-the-risk-of-dementia.html

BBC (2009) http://news.bbc.co.uk/1/hi/health/7968131.stm

The Telegraph (2009) http://www.telegraph.co.uk/news/health/elder/4319390/Supplements-of-vitamin-D-could-cut-Alzheimers-risk.html

Scientific American Mind (2009) https://www.scientificamerican.com/article/does-d-make-a-difference/

Time (2009) http://content.time.com/time/health/article/0,8599,1879386,00.html?iid=sr-link3

 

Supervision / Group

Postdoctoral researchers

  • Charlotte James Research Fellow
  • Ilianna Lourida
  • Janice Ranson Research Fellow

Postgraduate researchers

  • Fliss Guest PhD researcher

Research Technicians

  • Janice Alcott Administrator

Alumni

  • Jac Airdrie: Secured a PhD studentship at the University of Cardiff
  • Isobel Evans: Following her PhD Isobel became an Intervention Specialist at The Atkinson Secure Children's Home
  • Alice Holly: Following her PhD Alice was awarded a Killam Postdoctoral Fellowship at Dalhousie University
  • Harriet Hunt PhD researcher now Research Fellow at the University of Exeter
  • Thomas Littlejohns: Following his PhD he became a postdoctoral researcher at the University of Oxford
  • Ilianna Lourida: Following her PhD Ilianna became a postdoctoral researcher at the University of Exeter
  • Sharon Power: MSc Dissertation student
  • Janice Ranson: Following her PhD became a Postdoctoral Research Associate at the University of Exeter
  • Joanne Woodford: Following her PhD became a Research Fellow at the University of Exeter

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