Loading content
Dr Tristan Snowsill

Dr Tristan Snowsill

Research Fellow

6092

South Cloisters 3.09.2

I joined the health technology assessment group (PenTAG) within ESMI in August 2011, where my role is to develop models to explore the cost-effectiveness of health technologies, which include medicines, diagnostic tools and different strategies combining these technologies. This work usually involves reviewing the current health economic literature in a disease area, working with clinical experts to identify the key disease and service pathways and then producing a mathematical model which is parameterised from the most appropriate available data. In addition to developing new economic models, I also work on Single Technology Appraisals for NICE (National Institute for Health and Care Excellence), in which we critically appraise an evidence submission by a company (usually a pharmaceutical company).

I also perform a modest amount of peer review, usually reviewing 4-6 publications a year.

Before joining PenTAG I was a PhD student at the University of Bristol (2008-2011) where I developed text mining algorithms based on suffix trees (which often find use in computational genomics). In combination with my undergraduate Masters in Engineering Mathematics this gave me a solid background in mathematics, statistics and computer science.

Outside of work my hobbies include music, software development and cricket. I also regularly listen to podcasts, being a loyal listener to: More or Less [BBC], Westminster Hour [BBC], Weekly Political Review [BBC], Inside Health [BBC], Inside Science [BBC], Moral Maze [BBC], Analysis [BBC], File on Four [BBC], Friday Night Comedy [BBC], Comedy of the Week [BBC], Newsjack [BBC], Any Questions [BBC], The Infinite Monkey Cage [BBC], Politics Weekly [The Guardian], the New Statesman Podcast, Serial, Undisclosed, Freakonomics, the Laravel podcast, the ForceCast Network and the Titanium Physicists Podcast.

Qualifications

  • 2008 MEng (Bristol) - 1st class Hons
  • 2012 PhD (Bristol)

Research

Research interests

In addition to an interest in decision models for economic evaluation of health technologies, I also have interests in hierarchical statistical models, meta-analysis and statistical methods relating to genetics.

Research projects

  • Azacitidine for acute myeloid leukaemia with over 30% blasts: a single technology appraisal
  • Immunosuppressive agents for kidney transplantation (adults)
  • Immunosuppressive agents for kidney transplantation (children and adolescents)
  • Economic evaluation of strategies to identify and manage Lynch syndrome in early onset colorectal cancer patients
  • Erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer-treatment induced anaemia
  • Bosutinib for previously treated chronic myeloid leukaemia: a single technology appraisal
  • Economic evaluation of intraoperative tests (RD-100i OSNA and Metasin) for detecting sentinel Lymph node metastases in breast cancer
  • Prenatal screening for MODY (Maturity Onset Diabetes in the Young) genetic disorders using maternal blood

Key publications | Publications by category | Publications by year

Key publications


Snowsill TM (2017). Immunosuppressive therapy for kidney transplantation in adults: Economic model.  Abstract.  Full text.
Jones-Hughes T, Snowsill T, Haasova M, Coelho H, Crathorne L, Cooper C, Mujica-Mota R, Peters J, Varley-Campbell J, Huxley N, et al (2016). Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model. Health Technol Assess, 20(62), 1-594. Abstract.  Author URL.  Full text.
Haasova M, Snowsill T, Jones-Hughes T, Crathorne L, Cooper C, Varley-Campbell J, Mujica-Mota R, Coelho H, Huxley N, Lowe J, et al (2016). Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation. Health Technol Assess, 20(61), 1-324. Abstract.  Author URL.  Full text.
Snowsill T, Huxley N, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2015). A model-based assessment of the cost-utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients. BMC Cancer, 15 Abstract.  Author URL.  Full text.
Snowsill T, Huxley N, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2014). A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome. Health Technology Assessment, 18(58). Author URL.  Full text.

Publications by category


Journal articles

Snowsill TM, Moore J, Mujica Mota R, Peters JL, Jones-Hughes T, Huxley NJ, Coelho H, Haasova M, Cooper C, Lowe JA, et al (In Press). Immunosuppressive agents in adult kidney transplantation in the NHS: a model-based economic evaluation. Nephrology Dialysis Transplantation Full text.
Crathorne L, Huxley N, Haasova M, Snowsill T, Jones-Hughes T, Hoyle M, Briscoe S, Coelho H, Long H, Medina-Lara A, et al (In Press). The effectiveness and cost-effectiveness of erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer-treatment induced anaemia (including review of TA142): a systematic review and economic model. Health Technology Assessment Abstract.  Full text.
Tikhonova IA, Hoyle MW, Snowsill TM, Cooper C, Varley-Campbell JL, Rudin CE, Mujica Mota RE (2017). Azacitidine for Treating Acute Myeloid Leukaemia with More Than 30 % Bone Marrow Blasts: an Evidence Review Group Perspective of a National Institute for Health and Care Excellence Single Technology Appraisal. Pharmacoeconomics, 35(3), 363-373. Abstract.  Author URL.
Jones-Hughes T, Snowsill T, Haasova M, Coelho H, Crathorne L, Cooper C, Mujica-Mota R, Peters J, Varley-Campbell J, Huxley N, et al (2016). Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model. Health Technol Assess, 20(62), 1-594. Abstract.  Author URL.  Full text.
Haasova M, Snowsill T, Jones-Hughes T, Crathorne L, Cooper C, Varley-Campbell J, Mujica-Mota R, Coelho H, Huxley N, Lowe J, et al (2016). Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation. Health Technol Assess, 20(61), 1-324. Abstract.  Author URL.  Full text.
Snowsill T, Huxley N, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2015). A model-based assessment of the cost-utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients. BMC Cancer, 15 Abstract.  Author URL.  Full text.
Huxley N, Jones-Hughes T, Coelho H, Snowsill T, Cooper C, Meng Y, Hyde C, Mújica-Mota R (2015). A systematic review and economic evaluation of intraoperative tests [RD-100i one-step nucleic acid amplification (OSNA) system and Metasin test] for detecting sentinel lymph node metastases in breast cancer. Health Technol Assess, 19(2), v-215. Abstract.  Author URL.  Full text.
Snowsill T, Huxley N, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2014). A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome. Health Technology Assessment, 18(58). Author URL.  Full text.
Crathorne L, Huxley N, Haasova M, Snowsill T, Jones-Hughes T, Hoyle M, Briscoe S, Coelho H, Long L, Medina-Lara A, et al (2014). The effectiveness and cost-effectiveness of erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer-treatment induced anaemia (including review of TA142): a systematic review and economic model.  Author URL.
Flaounas I, Ali O, Turchi M, Snowsill T, Nicart F, De Bie T, Cristianini N (2011). NOAM: News outlets analysis and monitoring system. Proceedings of the ACM SIGMOD International Conference on Management of Data, 1275-1277. Abstract.
Snowsill T, Fyson N, De Bie T, Cristianini N (2011). Refining causality: Who copied from whom?. Proceedings of the ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, 466-474. Abstract.
Snowsill T, Flaounas I, De Bie T, Cristianini N (2010). Detecting events in a million New York times articles. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 6323 LNAI(PART 3), 615-618. Abstract.
Snowsill T, Nicart F, Stefani M, De Bie T, Cristianini N (2010). Finding surprising patterns in textual data streams. 2010 2nd International Workshop on Cognitive Information Processing, CIP2010, 405-410. Abstract.
Turchi M, Flaounas I, Ali O, De Bie T, Snowsill T, Cristianini N (2009). Found in translation. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 5782 LNAI(PART 2), 746-749. Abstract.

Conferences

Tikhonova IA, Hoyle M, Snowsill T, Cooper C, Varley-Campbell J, Rudin C, Mujica Mota R (2016). Azacitidine for Treating Acute Myeloid Leukaemia: a Nice Single Technology Appraisal. ISPOR.
Tikhonova IA, Hoyle M, Snowsill T, Crathorne L, Varley-Campbell J, Peters J, Briscoe S, Bond M, Huxley N (2016). Cost Effectiveness of Cetuximab and Panitumumab for First-Line RAS WT Metastatic Colorecal Cancer. ISPOR.
Haasova M, Jones-Hughes T, Peters J, Snowsill T, Coelho H, Crathorne L, Mujica Mota R, Varley-Campbell J, Huxley N, Moore J, et al (2016). Immunosuppressive therapy for renal transplantation in adults: a systematic review and network meta-analyses. Health Technology
Assessment international (HTAi). 10th - 14th May 2016. Abstract.
Huxley N, Snowsill T, Hoyle M, Crathorne L, Haasova M, Briscoe S, Coelho H, Medina-Lara A, Mujica-Mota R, Napier M, et al (2014). A COST-EFFECTIVENESS ANALYSIS OF ERYTHROPOIESIS-STIMULATING AGENTS FOR TREATING CANCER-TREATMENT INDUCED ANAEMIA.  Author URL.
Snowsill T, Huxley N, Hoyle M, Crathorne L, Haasova M, Briscoe S, Coelho H, Medina-Lara A, Mota MR, Napier M, et al (2014). MODEL-BASED COST-UTILITY ANALYSIS OF ERYTHROPOIESIS-STIMULATING AGENTS FOR THE TREATMENT OF CANCER-TREATMENT INDUCED ANAEMIA IN THE UK NHS.  Author URL.
Huxley N, Snowsill T, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2013). COST-EFFECTIVENESS OF SYSTEMATIC TESTING FOR LYNCH SYNDROME IN PATIENTS NEWLY DIAGNOSED WITH COLORECTAL CANCER IN THE UNITED KINGDOM.  Author URL.

Reports

Mujica-mota R, Varley-Campbell J, Tikhonova I, Cooper C, Hoyle MW, Rudin C, Rule S, Snowsill T (2016). Azacitidine for treating acute myeloid leukaemia with more than 30% bone marrow blasts: a Single Technology Appraisal. Author URL.  Full text.
Huxley N, Crathorne L, Varley-Campbell J, Tikhonova I, Snowsill T, Briscoe S, Peters J, Bond M, Napier M, Hoyle MW, et al (2015). Cetuximab (review of TA176) and panitumumab (partial review of TA240) for the first line treatment of metastatic colorectal cancer. MTA for NICE. Author URL.

Publications by year


In Press

Snowsill TM, Moore J, Mujica Mota R, Peters JL, Jones-Hughes T, Huxley NJ, Coelho H, Haasova M, Cooper C, Lowe JA, et al (In Press). Immunosuppressive agents in adult kidney transplantation in the NHS: a model-based economic evaluation. Nephrology Dialysis Transplantation Full text.
Crathorne L, Huxley N, Haasova M, Snowsill T, Jones-Hughes T, Hoyle M, Briscoe S, Coelho H, Long H, Medina-Lara A, et al (In Press). The effectiveness and cost-effectiveness of erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer-treatment induced anaemia (including review of TA142): a systematic review and economic model. Health Technology Assessment Abstract.  Full text.

2017

Tikhonova IA, Hoyle MW, Snowsill TM, Cooper C, Varley-Campbell JL, Rudin CE, Mujica Mota RE (2017). Azacitidine for Treating Acute Myeloid Leukaemia with More Than 30 % Bone Marrow Blasts: an Evidence Review Group Perspective of a National Institute for Health and Care Excellence Single Technology Appraisal. Pharmacoeconomics, 35(3), 363-373. Abstract.  Author URL.
Snowsill TM (2017). Immunosuppressive therapy for kidney transplantation in adults: Economic model.  Abstract.  Full text.

2016

Tikhonova IA, Hoyle M, Snowsill T, Cooper C, Varley-Campbell J, Rudin C, Mujica Mota R (2016). Azacitidine for Treating Acute Myeloid Leukaemia: a Nice Single Technology Appraisal. ISPOR.
Mujica-mota R, Varley-Campbell J, Tikhonova I, Cooper C, Hoyle MW, Rudin C, Rule S, Snowsill T (2016). Azacitidine for treating acute myeloid leukaemia with more than 30% bone marrow blasts: a Single Technology Appraisal. Author URL.  Full text.
Tikhonova IA, Hoyle M, Snowsill T, Crathorne L, Varley-Campbell J, Peters J, Briscoe S, Bond M, Huxley N (2016). Cost Effectiveness of Cetuximab and Panitumumab for First-Line RAS WT Metastatic Colorecal Cancer. ISPOR.
Jones-Hughes T, Snowsill T, Haasova M, Coelho H, Crathorne L, Cooper C, Mujica-Mota R, Peters J, Varley-Campbell J, Huxley N, et al (2016). Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model. Health Technol Assess, 20(62), 1-594. Abstract.  Author URL.  Full text.
Haasova M, Snowsill T, Jones-Hughes T, Crathorne L, Cooper C, Varley-Campbell J, Mujica-Mota R, Coelho H, Huxley N, Lowe J, et al (2016). Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation. Health Technol Assess, 20(61), 1-324. Abstract.  Author URL.  Full text.
Haasova M, Jones-Hughes T, Peters J, Snowsill T, Coelho H, Crathorne L, Mujica Mota R, Varley-Campbell J, Huxley N, Moore J, et al (2016). Immunosuppressive therapy for renal transplantation in adults: a systematic review and network meta-analyses. Health Technology
Assessment international (HTAi). 10th - 14th May 2016. Abstract.

2015

Snowsill T, Huxley N, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2015). A model-based assessment of the cost-utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients. BMC Cancer, 15 Abstract.  Author URL.  Full text.
Huxley N, Jones-Hughes T, Coelho H, Snowsill T, Cooper C, Meng Y, Hyde C, Mújica-Mota R (2015). A systematic review and economic evaluation of intraoperative tests [RD-100i one-step nucleic acid amplification (OSNA) system and Metasin test] for detecting sentinel lymph node metastases in breast cancer. Health Technol Assess, 19(2), v-215. Abstract.  Author URL.  Full text.
Huxley N, Crathorne L, Varley-Campbell J, Tikhonova I, Snowsill T, Briscoe S, Peters J, Bond M, Napier M, Hoyle MW, et al (2015). Cetuximab (review of TA176) and panitumumab (partial review of TA240) for the first line treatment of metastatic colorectal cancer. MTA for NICE. Author URL.

2014

Huxley N, Snowsill T, Hoyle M, Crathorne L, Haasova M, Briscoe S, Coelho H, Medina-Lara A, Mujica-Mota R, Napier M, et al (2014). A COST-EFFECTIVENESS ANALYSIS OF ERYTHROPOIESIS-STIMULATING AGENTS FOR TREATING CANCER-TREATMENT INDUCED ANAEMIA.  Author URL.
Snowsill T, Huxley N, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2014). A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome. Health Technology Assessment, 18(58). Author URL.  Full text.
Snowsill T, Huxley N, Hoyle M, Crathorne L, Haasova M, Briscoe S, Coelho H, Medina-Lara A, Mota MR, Napier M, et al (2014). MODEL-BASED COST-UTILITY ANALYSIS OF ERYTHROPOIESIS-STIMULATING AGENTS FOR THE TREATMENT OF CANCER-TREATMENT INDUCED ANAEMIA IN THE UK NHS.  Author URL.
Crathorne L, Huxley N, Haasova M, Snowsill T, Jones-Hughes T, Hoyle M, Briscoe S, Coelho H, Long L, Medina-Lara A, et al (2014). The effectiveness and cost-effectiveness of erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer-treatment induced anaemia (including review of TA142): a systematic review and economic model.  Author URL.

2013

Huxley N, Snowsill T, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2013). COST-EFFECTIVENESS OF SYSTEMATIC TESTING FOR LYNCH SYNDROME IN PATIENTS NEWLY DIAGNOSED WITH COLORECTAL CANCER IN THE UNITED KINGDOM.  Author URL.

2011

Flaounas I, Ali O, Turchi M, Snowsill T, Nicart F, De Bie T, Cristianini N (2011). NOAM: News outlets analysis and monitoring system. Proceedings of the ACM SIGMOD International Conference on Management of Data, 1275-1277. Abstract.
Snowsill T, Fyson N, De Bie T, Cristianini N (2011). Refining causality: Who copied from whom?. Proceedings of the ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, 466-474. Abstract.

2010

Snowsill T, Flaounas I, De Bie T, Cristianini N (2010). Detecting events in a million New York times articles. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 6323 LNAI(PART 3), 615-618. Abstract.
Snowsill T, Nicart F, Stefani M, De Bie T, Cristianini N (2010). Finding surprising patterns in textual data streams. 2010 2nd International Workshop on Cognitive Information Processing, CIP2010, 405-410. Abstract.

2009

Turchi M, Flaounas I, Ali O, De Bie T, Snowsill T, Cristianini N (2009). Found in translation. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 5782 LNAI(PART 2), 746-749. Abstract.

Back | Edit Profile