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University of Exeter Medical School

Dr Kaiyven Afi Leslie

Dr Kaiyven Afi Leslie

Postdoctoral Researcher

 RILD Building Level 4


University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK


Kaiyven was raised in Cameroon where he obtained his Bachelor’s degree in Medical laboratory sciences. He later on obtained funding from the Commonwealth Association to study a Masters in Immunology at the University of the West of England and a PhD at the University of Exeter. Kaiyven is interested in understanding the role of anti-inflammatory cytokines in the protection of beta cell inflammation in type 1 diabetes.


  • BSc Medical Laboratory Sciences(Hons)
  • MSc Biomedical Sciences (Immunology)
  • PhD Medical Studies

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Research interests

I am focused on studying the role of the transcription factor STAT6 in beta health. In particular we have shown that STAT6 activation protects beta cell from the detrimental actions of pro-inflammatory cytokines. We have shown that the activation of STAT6 by IL-4 and IL-13 increases the expression of a previously unregnised signal regulatory protein alpha which we are still uncovering its mechanism of protection.

Research projects

  • SIRPa in beta cell health


  • EFSD
  • DUK

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  • Biomedical Sciences



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