COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

Loading content

Megan Stevens

Research Fellow

 01392 72 5928

 

Overview

I carried out my PhD at the university of Bristol with Prof Dave Bates (now working at Nottingham University), Prof Steve Harper (Bristol), and Dr Sebastian Oltean (now working at the University of Exeter), studying the alternative splicing of VEGF-A in chronic kidney disease. After finishing my PhD, I developed an interest in the manipulation of VEGF-A splicing in diabetic nephropathy and continued to do a Post-doc with Dr Sebastian Oltean in Bristol. Since July 2017, I have a Research Fellow position at the University of Exeter to continue working with Dr Sebatian Oltean loking at novel alternative splicing events in diabetic nephropathy.

I am working on funding obtained by Dr Sebastian Oltean from the Diabetes UK. 

Qualifications

  • PhD in Glomerular Physiology and Alternative Splicing (University of Bristol, 2011-2014).
  • BSc in Physiology (University of Bristol, 2008-2011).

Research

Research interests

I am interested in alternative splicing in kidney disease, specifically, diabetic nephropathy. Much of our research has been focused on VEGF-A alternative splicing; however, our goals are to determine other proteins that are alternatively spliced in diabetic nephropathy, and to find ways to regulate the way these proteins are spliced as a novel therapeutic avenue.

 

Research projects

I am currently working on 1 project with Dr Sebastian Oltean: Alternative splicing in diabetic nephropathy.

 

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Stevens M, Oltean S (2019). Modulation of Receptor Tyrosine Kinase Activity through Alternative Splicing of Ligands and Receptors in the VEGF-A/VEGFR Axis. Cells, 8(4). Abstract.  Author URL.  Full text.
Stevens M, Oltean S (2018). Assessment of Kidney Function in Mouse Models of Glomerular Disease. J Vis Exp(136). Abstract.  Author URL.  Full text.
Stevens M, Oltean S (2018). Modulation of VEGF-A Alternative Splicing as a Novel Treatment in Chronic Kidney Disease. Genes (Basel), 9(2). Abstract.  Author URL.  Full text.

Publications by year


2019

Stevens M, Oltean S (2019). Modulation of Receptor Tyrosine Kinase Activity through Alternative Splicing of Ligands and Receptors in the VEGF-A/VEGFR Axis. Cells, 8(4). Abstract.  Author URL.  Full text.

2018

Stevens M, Oltean S (2018). Assessment of Kidney Function in Mouse Models of Glomerular Disease. J Vis Exp(136). Abstract.  Author URL.  Full text.
Stevens M, Oltean S (2018). Modulation of VEGF-A Alternative Splicing as a Novel Treatment in Chronic Kidney Disease. Genes (Basel), 9(2). Abstract.  Author URL.  Full text.

Megan_Stevens Details from cache as at 2019-10-19 13:48:57

Refresh publications

External Engagement and Impact

Editorial responsibilities

  • I am on the editorial board for the International Journal of Renal Diseases and Therapy.

Invited lectures

  • The International Splicing Conference 2016, Lisbon.
  • The international Splicing Conference 2018, Lisbon (confirmed invited speaker).

Teaching

Supervision / Group

Postgraduate researchers

  • Monica Lamici Ayine PhD Student

Back | Edit Profile