01392 72 5928
During my BSc degree in Physiology and the University of Bristol, I took a special interest in alternative splicing. From there I applied for a PhD position in Bristol with Prof Dave Bates (now working at Nottingham University), Prof Steve Harper (Bristol), and Dr Sebastian Oltean (now working at the University of Exeter), to study alternative splicing of VEGF-A in chronic kidney disease. After finishing my PhD, I had developed an interest in the manipulation of VEGF-A splicing in diabetic nephropathy and continued to do a Post-doc with Dr Sebastian Oltean in Bristol. Since July 2017, I have a Research Fellow position at the University of Exeter to continue working with Dr Sebatian Oltean.
I am working on grants/funding obtained by Dr Sebastian Oltean from the BHF, Richard Bright VEGF Research Trust, and Boehringer Ingelheim.
- PhD in Glomerular Physiology and Alternative Splicing (University of Bristol, 2011-2014).
- BSc in Physiology (University of Bristol, 2008-2011).
I am interested in alternative splicing in kidney disease, specifically, diabetic nephropathy. Much of our research has been focused on VEGF-A alternative splicing; however, our goals are to determine other proteins that are alternatively spliced in diabetic nephropathy, and to find ways to regulate the way these proteins are spliced as a novel therapeutic avenue.
I am currently working on 2 projects with Dr Sebastian Oltean:
1. Alternative splicing in diabetic nephropathy.
2. Detection of genomic mutations in blood and urine free circulating tumour DNA in inoperable and metastatic lung adenocarcinoma harboring an EGFR mutation on tissue.
Publications by category
Publications by year
Megan_Stevens Details from cache as at 2018-12-16 16:21:03
External Engagment and Impact
- I am on the editorial board for the International Journal of Renal Diseases and Therapy.
- The International Splicing Conference 2016, Lisbon.
- The international Splicing Conference 2018, Lisbon (confirmed invited speaker).