COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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Dr Harry Green

Independent Research Fellow

 07979 464009

 RILD Building 3.03

 

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Overview

Harry is an E3 funded Independent Research Fellow in statistical modeling of disease progression. His PhD was in biophysical modeling of cardiac electrophysiology under Professor John Terry.

Harry's current research aim is to use advanced statistical modeling and machine learning approaches to build predictive models of Type 2 Diabetes progression and glycaemic control and identify causal risk factors for rising HbA1C levels.

Prior to the E3 fellowship, Harry worked as a Biomedical Statistican for Exeter's IBD Pharmacogenetics team, where he developed predictive models for treatment failure in Anti-TNF therapy for luminal Crohn's disease, identified genetic variants associated with disease risk and adverse event risk, and used genetic epidemiology to identify causal risk factors for gastrointestinal conditions.

Qualifications

  • PhD Applied Mathematics – University of Exeter
  • MSc by Research Applied Mathematics – Oxford Brookes University
  • BSc Mathematics – University of Portsmouth

 

Research group links

Research

Research interests

My research interests are in the development and application of mathematical and statistical techniques with practical clinical use, particularly in predictive modeling in healthcare. While I currently work in disease progression in Type 2 Diabetes, my research experience spans cardiac biophysics, genetic epidemiology and modelling anti-TNF treatment failure.

Links


Publications

Key publications | Publications by category | Publications by year

Key publications


Bewshea CM, Ahmad T, Kennedy N, Goodhand J, McDonald T, Green H (2019). Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study. Lancet Gastroenterology and Hepatology Full text.

Publications by category


Journal articles

Lin S, Green HD, Hendy P, Heerasing NM, Chanchlani N, Hamilton B, Walker GJ, Heap GA, Hobart J, Martin RJ, et al (2020). Clinical features and genetic risk of demyelination following anti-TNF treatment. J Crohns Colitis Abstract.  Author URL.  Full text.
Green HD, Beaumont RN, Wood AR, Hamilton B, Jones SE, Goodhand JR, Kennedy NA, Ahmad T, Yaghootkar H, Weedon MN, et al (2020). Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian-randomization study. International Journal of Epidemiology Abstract.  Full text.
Hamilton B, Green H, Heerasing N, Hendy P, Moore L, Chanchlani N, Walker G, Bewshea C, Kennedy NA, Ahmad T, et al (2020). Incidence and prevalence of inflammatory bowel disease in Devon, UK. Frontline Gastroenterology Abstract.
Walker GJ, Lin S, Chanchlani N, Thomas A, Hendy P, Heerasing N, Moore L, Green HD, Chee D, Bewshea C, et al (2020). Quality improvement project identifies factors associated with delay in IBD diagnosis. Alimentary Pharmacology & Therapeutics, 52(3), 471-480.
Green HD, Beaumont RN, Thomas A, Hamilton B, Wood AR, Sharp S, Jones SE, Tyrrell J, Walker G, Goodhand J, et al (2019). Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis. J Crohns Colitis, 13(12), 1578-1582. Abstract.  Author URL.  Full text.
Bewshea CM, Ahmad T, Kennedy N, Goodhand J, McDonald T, Green H (2019). Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study. Lancet Gastroenterology and Hepatology Full text.
Green HD, Thomas G, Terry JR (2017). Signal reconstruction of pulmonary vein recordings using a phenomenological mathematical model: Application to pulmonary vein isolation therapy. Frontiers in Physiology, 8(JUL). Abstract.  Full text.

Publications by year


2020

Lin S, Green HD, Hendy P, Heerasing NM, Chanchlani N, Hamilton B, Walker GJ, Heap GA, Hobart J, Martin RJ, et al (2020). Clinical features and genetic risk of demyelination following anti-TNF treatment. J Crohns Colitis Abstract.  Author URL.  Full text.
Green HD, Beaumont RN, Wood AR, Hamilton B, Jones SE, Goodhand JR, Kennedy NA, Ahmad T, Yaghootkar H, Weedon MN, et al (2020). Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian-randomization study. International Journal of Epidemiology Abstract.  Full text.
Hamilton B, Green H, Heerasing N, Hendy P, Moore L, Chanchlani N, Walker G, Bewshea C, Kennedy NA, Ahmad T, et al (2020). Incidence and prevalence of inflammatory bowel disease in Devon, UK. Frontline Gastroenterology Abstract.
Walker GJ, Lin S, Chanchlani N, Thomas A, Hendy P, Heerasing N, Moore L, Green HD, Chee D, Bewshea C, et al (2020). Quality improvement project identifies factors associated with delay in IBD diagnosis. Alimentary Pharmacology & Therapeutics, 52(3), 471-480.

2019

Green HD, Beaumont RN, Thomas A, Hamilton B, Wood AR, Sharp S, Jones SE, Tyrrell J, Walker G, Goodhand J, et al (2019). Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis. J Crohns Colitis, 13(12), 1578-1582. Abstract.  Author URL.  Full text.
Bewshea CM, Ahmad T, Kennedy N, Goodhand J, McDonald T, Green H (2019). Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study. Lancet Gastroenterology and Hepatology Full text.

2017

Green HD, Thomas G, Terry JR (2017). Signal reconstruction of pulmonary vein recordings using a phenomenological mathematical model: Application to pulmonary vein isolation therapy. Frontiers in Physiology, 8(JUL). Abstract.  Full text.

Harry_Green Details from cache as at 2020-08-06 17:30:29

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External Engagement and Impact

Awards

  • Winner - Best Postgraduate Demonstrator, Department of Mathematics and Computer Science, 2013
  • Winner - Best Postgraduate Demonstrator, Department of Mathematics and Computer Science, 2015
  • Nominated - Best Postgraduate Demonstrator, University of Exeter, 2015
  • Winner - Best Postgraduate Demonstrator, Department of Mathematics and Computer Science, 2017
  • Runner up – Best Poster Presentation, BioDynamics 2016

Invited lectures & workshops

  • Mathematical Modelling of the Pulmonary Vein signals during Radiofrequency Ablation of Atrial Fibrillation - Institute of Mathematics and its Applications Early Career Mathematicians Conference – Keynote, 2015
  • Mathematical Modelling of Atrial Electrograms and Application to Radiofrequency Ablation Treatment – University Hospital Bordeaux – Invited International Speaker, 2015

Teaching

In my previous role as a teaching consultant in mathematics, I taught a range of courses in the first year, including dynamics, elementary calculus, advanced calculus, programming for mathematics, and mathematical investigations.

 

 

Supervision / Group

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