COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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 Garan Jones

Garan Jones

PhD Student

 College House 1.07

 

College House, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK

Overview

Garan joined Public Health England (formerly the Health Protection Agency) in 2008 as a Bioinformatician working with the European Working Group on Legionella Infection (EWGLI), specialising in sequence based typing of Legionella. In late 2009, Garan moved groups to the Gastrointestinal, Enteric and Zoonotic Infections (GEZI) department as a Bioinformatician focused on the epidemiology of various pathogen outbreaks including Escherichia Coli, Campylobacter Jejuni and zoonotic pathogens. This was followed in 2012 with a relocation to the International Microinjection Tracking System (IMiTS) at the Wellcome Trust Sanger Institute in Cambridge as a Senior Developer, before moving to Exeter to complete an MRes in Bioinformatics. Following which Garan spent 4 year working in Clinical Bioinformatics with the NHS based at the Royal Devon & Exeter, mainly working on Targeted / Exome Next Generation Sequencing and rare disease analysis.

 

Qualifications

  • BSc(Hons) Molecular Cell Biology, University of Southampton
  • PgDip Medical Molecular Genetics, Aberdeen University
  • MSc Computer Science, University of Swansea
  • MRes Bioinformatics, University of Exeter

Research

Research interests

Currently working on UK Biobank analysis with Dr. Luke Pilling and Prof. David Melzer. Includes looking at the associations between genotypes and phenotypes related to aging, such as Sarcopenia and low lung function.

 

Inflammation and its impact on aging; Rare disease and sequencing; Bioinformatics; Research software development

Research networks

CHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology)

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Jones G, Pilling LC, Kuo C-L, Kuchel G, Ferrucci L, Melzer D (2020). Sarcopenia and Variation in the Human Leukocyte Antigen Complex. J Gerontol a Biol Sci Med Sci, 75(2), 301-308. Abstract.  Author URL.  Full text.
Pilling L, Tamosauskaite J, Jones G, Wood A, Jones L, Kuo C-L, Kuchel G, Ferrucci L, Melzer D (2019). Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank. BMJ Full text.
Stals KL, Wakeling M, Baptista J, Caswell R, Parrish A, Rankin J, Tysoe C, Jones G, Gunning AC, Lango Allen H, et al (2018). Diagnosis of lethal or prenatal-onset autosomal recessive disorders by parental exome sequencing. Prenat Diagn, 38(1), 33-43. Abstract.  Author URL.
Parrish A, Caswell R, Jones G, Watson CM, Crinnion LA, Ellard S (2017). An enhanced method for targeted next generation sequencing copy number variant detection using ExomeDepth. Wellcome Open Research, 2, 49-49. Abstract.
De Franco E, Flanagan SE, Yagi T, Abreu D, Mahadevan J, Johnson MB, Jones G, Acosta F, Mulaudzi M, Lek N, et al (2017). Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts. Diabetes, 66(7), 2044-2053. Abstract.  Author URL.  Full text.
Underwood AP, Jones G, Mentasti M, Fry NK, Harrison TG (2013). Comparison of the Legionella pneumophila population structure as determined by sequence-based typing and whole genome sequencing. BMC Microbiol, 13 Abstract.  Author URL.

Publications by year


2020

Jones G, Pilling LC, Kuo C-L, Kuchel G, Ferrucci L, Melzer D (2020). Sarcopenia and Variation in the Human Leukocyte Antigen Complex. J Gerontol a Biol Sci Med Sci, 75(2), 301-308. Abstract.  Author URL.  Full text.

2019

Pilling L, Tamosauskaite J, Jones G, Wood A, Jones L, Kuo C-L, Kuchel G, Ferrucci L, Melzer D (2019). Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank. BMJ Full text.

2018

Stals KL, Wakeling M, Baptista J, Caswell R, Parrish A, Rankin J, Tysoe C, Jones G, Gunning AC, Lango Allen H, et al (2018). Diagnosis of lethal or prenatal-onset autosomal recessive disorders by parental exome sequencing. Prenat Diagn, 38(1), 33-43. Abstract.  Author URL.

2017

Parrish A, Caswell R, Jones G, Watson CM, Crinnion LA, Ellard S (2017). An enhanced method for targeted next generation sequencing copy number variant detection using ExomeDepth. Wellcome Open Research, 2, 49-49. Abstract.
De Franco E, Flanagan SE, Yagi T, Abreu D, Mahadevan J, Johnson MB, Jones G, Acosta F, Mulaudzi M, Lek N, et al (2017). Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts. Diabetes, 66(7), 2044-2053. Abstract.  Author URL.  Full text.

2013

Underwood AP, Jones G, Mentasti M, Fry NK, Harrison TG (2013). Comparison of the Legionella pneumophila population structure as determined by sequence-based typing and whole genome sequencing. BMC Microbiol, 13 Abstract.  Author URL.

Garan_Jones Details from cache as at 2020-04-06 03:35:51

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External Engagement and Impact

External positions

Lead Editor - STP Clinical Bioinformatics 2019-2020 curriculum review

  • Review syllabus content for 3-year National Healthcare School training scheme

  • Production of update syllabus for 2020 onwards

  • Act as facilitator for stakeholder meetings


Other

Association of Clinical Genomics member / British Society for Genetic Medicine member

Bioinformatics representative for the ACGS Workforce development committee 2015-2017

Teaching

Supervision / Group

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