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University of Exeter Medical School

Dr Francesco Casanova

Dr Francesco Casanova

Research Fellow

 f.casanova@exeter.ac.uk

 College House 1.09

 

College House, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK


Overview

Francesco Casanova obtained his PhD in Exercise Physiology from Bangor University and in 2010 joined the University of Exeter working in the Diabetes & Vascular Medicine Research Centre led by Professor Angela Shore. Francesco worked on the SUMMIT project (http://www.imi-summit.eu/), an IMI funded project with 29 partners.

Francesco joined the Complex Traits Genomics team in 2019 after collaborating with the team for a few years. Francesco worked with Dr Jess Tyrrell to explore causal relationships between metabolic traits, such as obesity and type 2 diabetes, and mental health traits.

In March 2022 Francesco joined the Epidemiology and Public Health group to investigate the role of plasma and brain iron in cognitive decline and dementia using Mendelian randomization. This project is a collaboration between Exeter and the National Institute of Aging (NIA) in Baltimore (USA).

Qualifications

PhD

BSc

AFHEA

Research group links

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Research

Research interests

Francesco's research is focusing on the association between metabolic traits (for example obesity and type 2 diabetes) and mental health and cognitive phenotypes using Mendelian Randomization and Gene by Environment interaction techniques, amongst others. Francesco is also interested in exploring the causal role of iron in dementia.

He is interested in exploring how the association between metabolic and mental health/cognition differs depending on ethnicity and psycosocial factors, currently focusing on European and Chinese populations using the UK Biobank and the China Kadoorie Biobank. Francesco's research is also investigating the positive role of physical activity on mental health outcomes.

Research projects

Research networks

Exeter Brain Network

Deep Dementia Phenotyping Network (DEMON)

https://demondementia.com/

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Publications

Journal articles

Tyrrell J, O'Loughlin J, Casanova F, Bowden J, Freathy R, Watkins E (In Press). BMI and Well-being in people of East Asian and European Ancestry: a Mendelian Randomisation Study. Translational Psychiatry Abstract.
Casanova F, Gooding K, Shore A, Adingupu D, Mawson D, Ball C, Anning C, Aizawa K, Gates P, Strain W, et al (In Press). Weight change and sulphonylurea therapy are related to three-year change in microvascular function in people with type 2 diabetes. Diabetologia
Casanova F, Tian Q, Atkins JL, Wood AR, Williamson D, Qian Y, Zweibaum D, Ding J, Melzer D, Ferrucci L, et al (2024). Iron and risk of dementia: Mendelian randomisation analysis in UK Biobank. Journal of Medical Genetics Abstract.
Tian Q, Zweibaum DA, Pilling LC, Casanova F, Qian Y, Atkins JL, Melzer D, Ding J, Ferrucci L (2024). Is Mitochondrial DNA Copy Number from Human Blood Associated with Iron Deposits in the Brain?. Antioxid Redox Signal Abstract.  Author URL.
Aizawa K, Gates PE, Mawson DM, Casanova F, Gooding KM, Hope SV, Goncalves I, Nilsson J, Khan F, Colhoun HM, et al (2024). Type 2 diabetes exacerbates changes in blood pressure-independent arterial stiffness: cross-sectional and longitudinal evidence from the SUMMIT study. J Appl Physiol (1985), 136(1), 13-22. Abstract.  Author URL.
Karageorgiou V, Casanova F, O'Loughlin J, Green H, McKinley TJ, Bowden J, Tyrrell J (2023). Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study. BMC Med, 21(1). Abstract.  Author URL.
Casanova F, O'Loughlin J, Karageorgiou V, Beaumont RN, Bowden J, Wood AR, Tyrrell J (2023). Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study. BMC Med, 21(1). Abstract.  Author URL.
O'Loughlin J, Casanova F, Fairhurst-Hunter Z, Hughes A, Bowden J, Watkins ER, Freathy RM, Millwood IY, Lin K, Chen Z, et al (2023). Mendelian randomisation study of body composition and depression in people of East Asian ancestry highlights potential setting-specific causality. BMC Med, 21(1). Abstract.  Author URL.
Tian Q, Zweibaum D, Qian Y, Pilling L, Casanova F, Atkins JL, Melzer D, Ding J, Ferrucci L (2023). Mitochondrial DNA copy number predicts dementia risk with early mobility impairment. Alzheimer's & Dementia, 19(S12).
Smith MC, O’Loughlin J, Karageorgiou V, Casanova F, Williams GKR, Hilton M, Tyrrell J (2023). The genetics of falling susceptibility and identification of causal risk factors. Scientific Reports, 13(1). Abstract.
Casanova F, Tyrrell J, Beaumont RN, Ji Y, Jones SE, Hattersley AT, Weedon MN, Murray A, Shore AC, Frayling TM, et al (2022). Corrigendum to: a genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio. Human Molecular Genetics, 31(9).
Khan F, Gonçalves I, Shore AC, Natali A, Palombo C, Colhoun HM, Östling G, Casanova F, Kennbäck C, Aizawa K, et al (2022). Plaque characteristics and biomarkers predicting regression and progression of carotid atherosclerosis. Cell Rep Med, 3(7). Abstract.  Author URL.
Gilchrist M, Casanova F, Tyrrell JS, Cannon S, Wood AR, Fife N, Young K, Oram RA, Weedon MN (2022). Prevalence of Fabry disease-causing variants in the UK Biobank. Journal of Medical Genetics, 60(4), 391-396. Abstract.
Aizawa K, Hughes AD, Casanova F, Gates PE, Mawson DM, Gooding KM, Gilchrist M, Goncalves I, Nilsson J, Khan F, et al (2022). Reservoir Pressure Integral is Independently Associated with the Reduction in Renal Function in Older Adults. Hypertension, 79(10), 2364-2372. Abstract.  Author URL.
Casanova F, O’Loughlin J, Lewis C, Frayling TM, Wood AR, Tyrrell J (2022). Simulated distributions from negative experiments highlight the importance of the body mass index distribution in explaining depression–body mass index genetic risk score interactions. International Journal of Epidemiology, 51(5), 1581-1592. Abstract.
Cresswell M, Casanova F, Beaumont RN, Wood AR, Ronan N, Hilton MP, Tyrrell J (2022). Understanding Factors That Cause Tinnitus: a Mendelian Randomization Study in the UK Biobank. Ear Hear, 43(1), 70-80. Abstract.  Author URL.
Aizawa K, Gates PE, Mawson DM, Elyas S, Casanova F, Gooding KM, Adingupu DD, Strain WD, Shore AC (2021). Carotid–femoral pulse wave velocity acquisition methods and their associations with cardiovascular risk factors and subclinical biomarkers of vascular health. Journal of Hypertension, 40(4), 658-665. Abstract.
Elyas S, Adingupu D, Aizawa K, Casanova F, Gooding K, Fulford J, Mawson D, Gates PE, Shore AC, Strain D, et al (2021). Cerebral small vessel disease, systemic vascular characteristics and potential therapeutic targets. Aging, 13(18), 22030-22039.
Casanova F, O'Loughlin J, Martin S, Beaumont RN, Wood AR, Watkins ER, Freathy RM, Hagenaars SP, Frayling TM, Yaghootkar H, et al (2021). Higher adiposity and mental health: causal inference using Mendelian randomization. Hum Mol Genet, 30(24), 2371-2382. Abstract.  Author URL.
Meertens R, Knapp KM, Strain WD, Casanova F, Ball S, Fulford J, Thorn C (2021). In vivo Measurement of Intraosseous Vascular Haemodynamic Markers in Human Bone Tissue Utilising Near Infrared Spectroscopy. Frontiers in Physiology, 12 Abstract.
Aizawa K, Casanova F, Gates PE, Mawson DM, Gooding KM, Strain WD, Östling G, Nilsson J, Khan F, Colhoun HM, et al (2021). Reservoir-Excess Pressure Parameters Independently Predict Cardiovascular Events in Individuals with Type 2 Diabetes. Hypertension, 78(1), 40-50. Abstract.
O'Loughlin J, Casanova F, Jones SE, Hagenaars SP, Beaumont RN, Freathy RM, Watkins ER, Vetter C, Rutter MK, Cain SW, et al (2021). Using Mendelian Randomisation methods to understand whether diurnal preference is causally related to mental health. Mol Psychiatry, 26(11), 6305-6316. Abstract.  Author URL.
Casanova F, Wood AR, Yaghootkar H, Beaumont RN, Jones SE, Gooding KM, Aizawa K, Strain WD, Hattersley AT, Khan F, et al (2020). A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function. Diabetes, 69(5), 1072-1082. Abstract.  Author URL.
Aizawa K, Casanova F, Mawson D, Gooding K, Elyas S, Adingupu D, Strain D, Gates P, Shore A (2020). P17 Comparisons of Carotid-femoral Pulse Wave Velocity Obtained from the Surface-distance Measurement and from the Population-derived Distance Formula: Associations with Macro- and Microvascular Alterations in Older Adults. Artery Research, 25(Suppl 1), s60-s60.
Casanova F, Tyrrell J, Beaumont RN, Ji Y, Jones SE, Hattersley AT, Weedon MN, Murray A, Shore AC, Frayling TM, et al (2019). A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio. Hum Mol Genet, 28(24), 4197-4207. Abstract.  Author URL.
Aizawa K, Ramalli A, Sbragi S, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2019). Arterial wall shear rate response to reactive hyperaemia is markedly different between young and older humans. J Physiol, 597(16), 4151-4163. Abstract.  Author URL.
Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Östling G, Khan F, Colhoun HM, Palombo C, et al (2018). 3.2 Reservoir Pressure Integral is Independently Associated with the Reduction in Renal Function in an Older Population. Artery Research, 24(1), 72-73.
Frayling TM (2018). A Common Allele in FGF21 Associated with Sugar Intake is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure. Cell Reports, 23(2), 327-336.
van Zuydam NR, Ahlqvist E, Sandholm N, Deshmukh H, Rayner NW, Abdalla M, Ladenvall C, Ziemek D, Fauman E, Robertson NR, et al (2018). A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects with Type 2 Diabetes. Diabetes, 67(7), 1414-1427. Abstract.  Author URL.
Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2018). Brachial artery vasodilatory response and wall shear rate determined by multigate Doppler in a healthy young cohort. J Appl Physiol (1985), 124(1), 150-159. Abstract.  Author URL.
Meertens RM, Casanova F, Knapp KM, Thorn C, Strain WD (2018). Use of Near-Infrared Systems for Investigations of Hemodynamics in Human in Vivo Bone Tissue: a Systematic Review. Journal of Orthopaedic Research
Shore AC, Colhoun HM, Natali A, Palombo C, Khan F, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, et al (2018). Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: the SUMMIT VIP Study. Diabetes Care, 41(10), 2212-2219. Abstract.  Author URL.
Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn C, Shore A, Gates P, Palombo C, et al (2017). P19: Influence of Brachial Artery Stiffness on Flow-Mediated Dilatation in Healthy Young and Older Populations. Artery Research, 20(1), 98-98.
Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn C, Shore A, Gates P, Palombo C, et al (2017). P74: Wall Shear Rate and Brachial Artery Flow-Mediated Dilatory Response Between Healthy Young and Older Populations Using Multi-Gate Spectral Doppler Ultrasound. Artery Research, 20(1), 73-73.
Casanova F, Adingupu DD, Adams F, Gooding KM, Looker HC, Aizawa K, Dove F, Elyas S, Belch JJF, Gates PE, et al (2017). The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control. Cardiovasc Diabetol, 16(1). Abstract.  Author URL.
Gonçalves I, Edsfeldt A, Colhoun HM, Shore AC, Palombo C, Natali A, Fredrikson GN, Björkbacka H, Wigren M, Bengtsson E, et al (2016). Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. BMC Cardiovasc Disord, 16(1). Abstract.  Author URL.
Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn C, Shore A, Gates P, Palombo C, et al (2016). Brachial artery flow-mediated dilatation: different patterns of wall shear rate increase during reactive hyperaemia. Artery Research, 16(C), 67-68.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Shore AC, Strain WD, Gates PE (2016). Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. Ultrasound Med Biol, 42(5), 1130-1137. Abstract.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Strain WD, Shore AC, Gates PE (2016). Reactivity to low-flow as a potential determinant for brachial artery flow-mediated vasodilatation. Physiol Rep, 4(12). Abstract.  Author URL.
Bokori-Brown M, Petrov PG, Khafaji MA, Mughal MK, Naylor CE, Shore AC, Gooding KM, Casanova F, Mitchell TJ, Titball RW, et al (2016). Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES. J Biol Chem, 291(19), 10210-10227. Abstract.  Author URL.
Meertens RM, Knapp KM, Strain WD, Casanova F (2016). The Effects of Lumbar Sympathectomy on Bone and Soft Tissue Haemodynamics of the Leg recorded using Near Infrared Spectroscopy: a Case Report. Journal of Biomedical Engineering and Informatics, 3, 28-32.
Aizawa K, Casanova F, Mawson D, Elyas S, Adingupu DD, Gooding KM, Strain WD, Park CM, Parker KH, Gates PE, et al (2016). [PP.11.05] RESERVOIR-PRESSURE ANALYSIS IN TYPE 2 DIABETES INDIVIDUALS WITH CARDIOVASCULAR DISEASE. Journal of Hypertension, 34(Supplement 2), e178-e178.
Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW, et al (2015). Blood Oxygen Saturation After Ischemia is Altered with Abnormal Microvascular Reperfusion. Microcirculation, 22(4), 294-305. Abstract.  Author URL.
Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, et al (2015). Elevated Plasma Levels of MMP-12 Are Associated with Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects with Type 2 Diabetes. Arterioscler Thromb Vasc Biol, 35(7), 1723-1731. Abstract.  Author URL.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. Journal of Internal Medicine, 278(3), 291-302. Abstract.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. J Intern Med, 278(3), 291-302. Abstract.  Author URL.
Aizawa. K, Casanova F, Mawson D, Elyas S, Adingupu D, Gooding K, Strain D, Shore A, Gates P (2015). P3.5 TYPE 2 DIABETES EXACERBATES CAROTID ARTERY ECHOGENICITY AND CENTRAL ARTERY STIFFNESS IN MIDDLE-AGED AND OLDER INDIVIDUALS. Artery Research, 12(C), 11-11.
Cooney JK, Moore JP, Ahmad YA, Jones JG, Lemmey AB, Casanova F, Maddison PJ, Thom JM (2013). A simple step test to estimate cardio-respiratory fitness levels of rheumatoid arthritis patients in a clinical setting. Int J Rheumatol, 2013 Abstract.  Author URL.
Adingupu DD, Elyas S, Casanova F, Gates PE, Shore AC, Strain WD (2013). Microvascular autoregulatory response to ischaemia and pulse pressure. JOURNAL OF HUMAN HYPERTENSION, 27(10), 652-653.  Author URL.
Adingupu DD, Thorn C, Casanova F, Elyas S, Gates PE, Strain WD, Shore AC (2013). Microvascular autoregulatory response to ischaemia in the skin and association with mean blood oxygen saturation. JOURNAL OF HUMAN HYPERTENSION, 27(10), 640-641.  Author URL.
Lemmey AB, Marcora SM, Chester K, Wilson S, Casanova F, Maddison PJ (2009). Effects of high-intensity resistance training in patients with rheumatoid arthritis: a randomized controlled trial. Arthritis Rheum, 61(12), 1726-1734. Abstract.  Author URL.
Marcora SM, Casanova F, Fortes MB, Maddison PJ (2007). Validity and reliability of the Siconolfi Step Test for assessment of physical fitness in patients with systemic lupus erythematosus. Arthritis Rheum, 57(6), 1007-1011. Abstract.  Author URL.
Marcora S, Casanova F, Williams E, Jones J, Elamanchi R, Lemmey A (2006). Preliminary evidence for cachexia in patients with well-established ankylosing spondylitis. RHEUMATOLOGY, 45(11), 1385-1388.  Author URL.
Marcora S, Casanova F, Williams E, Jones J, Elamanchi R, Lemmey A (2006). Preliminary evidence for cachexia in patients with well-established ankylosing spondylitis. Rheumatology (Oxford), 45(11), 1385-1388. Abstract.  Author URL.
Fortes MB, Casanova F, Marcora S (2006). Reliability and Validity of the Siconolfi Step-Test in Patients with Systemic Lupus Erythematosus. Medicine & Science in Sports & Exercise, 38(Supplement).
La Torre A, Impellizzeri FM, Rampinini E, Casanova F, Alberti G, Marcora SM (2005). Cardiovascular responses to aerobic step dance sessions with and without appendicular overload. J Sports Med Phys Fitness, 45(3), 264-269. Abstract.  Author URL.

Conferences

MacDonald W, Casanova F, Gooding K, Aizawa K, Shore A, Khan F (2023). 9 Monocyte chemoattractant protein-1 as a biomarker of vascular dysfunction in patients with type 2 diabetes.  Author URL.
Jordan AN, Aizawa K, Gooding KM, Llewellyn D, Casanova F, Mawson DM, Gates PE, Adingupu DD, Elyas S, Hope S, et al (2022). Arterial haemodynamic parameters linked to arterial pulsatility, excess wave propagation and cognitive function. European Society of Hypertension. 17th - 20th Jun 2022. Abstract.
Tyrrell J, Gillett A, Casanova F, Young K, Green H, Lewis C, Hagenaars S (2022). The impact of depression. diagnosis on diabetes and lifetime hyperglycaemia. World Congress of Psychiatric Genetic (WCPG). 13th - 17th Sep 2022.
Hagenaars S, Casanova F, Gillett A, Green H, Lewis C, Tyrrell J (2021). ASSESSING THE IMPACT OF DEPRESSION DIAGNOSIS ON DIABETES AND LIFETIME HYPERGLYCAEMIA.  Author URL.
Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Ostling G, Khan F, Colhoun HM, Palombo C, et al (2021). ELEVATED EXCESS PRESSURE INTEGRAL IS ASSOCIATED WITH VASCULAR BIOMARKERS OF SUBCLINICAL ATHEROSCLEROSIS IN OLDER ADULTS.  Author URL.
O'Loughlin J, Casanova F, Hughes A, Bowden J, Watkins E, Freathy R, Walters R, Howe L, Kuchenbaecker K, Tyrrell J, et al (2021). HIGHER BMI CAUSES LOWER ODDS OF DEPRESSION IN INDIVIDUALS OF EAST ASIAN ANCESTRY.  Author URL.
Karageorgiou V, Casanova F, O'Loughlin J, Bowden J, Tyrrell J (2021). INFLAMMATION AND OVERWEIGHT AS PUTATIVE RISK FACTORS FOR DEPRESSION: a MULTIVARIABLE MENDELIAN RANDOMIZATION STUDY.  Author URL.
Gilchrist M, Casanova F, Tyrrell J, Fife N, Young K, Oram R, Weedon M (2021). MO042PREVALENCE OF FABRY DISEASE CAUSING VARIANTS IN THE UK BIOBANK. Abstract.
Casanova F, Jones S, O'Loughlin J, Beaumont R, Wood A, Bowden J, Tyrrell J (2021). PHYSICAL ACTIVITY AND MENTAL HEALTH: a MENDELIAN RANDOMIZATION STUDY.  Author URL.
Gilchrist M, Casanova F, Tyrrell J, Fife N, Young K, Oram R, Weedon M (2021). PREVALENCE OF FABRY DISEASE CAUSING VARIANTS IN THE UK BIOBANK.  Author URL.
Gooding K, Shore AC, Casanova F, Ball C, Wilkes L, Ling R, Agardh E (2020). Examining the Impact of Type 2 Diabetes on Longitudinal Changes in Fovea Thickness.  Author URL.
Meertens R, Knapp K, Casanova F, Ball S, Strain W (2020). Near infrared spectroscopy for the investigation of vascular haemodynamics in human bone in vivo. Bone Research Society Annual Meeting. 6th - 8th Jul 2020.
Meertens R, Knapp K, Casanova F, Ball S, Fulford J, Merson S, Strain W (2020). Sex-based differences in vascular haemodynamics at the proximal tibia. European Congress of Radiology. 15th - 19th Jul 2020.
Meertens R, Knapp K, Casanova F, Ball S, Fulford J, Merson S, Strain W (2020). Vascular measurements of the proximal tibia and their associations with bone mineral density. European Congress of Radiology. 15th - 19th Jul 2020.
Gooding K, Chapman D, Casanova F, Ball C, Whatmore JL, Ling R, Shore AC (2019). A PRELIMINARY STUDY EXAMINING ALBUMINURIA, MACULAR THICKNESS AND GLYCOCALYX SHEDDING IN THE EARLY STAGES OF DIABETIC RETINOPATHY IN TYPE 2 DIABETES.  Author URL.
Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Ostling G, Khan F, Colhoun HM, Palombo C, et al (2019). ALTERED CENTRAL HAEMODYNAMIC PARAMETERS DERIVED FROM RESERVOIR PRESSURE ANALYSIS: ASSOCIATION WITH BIOMARKERS OF TARGET ORGAN DAMAGE IN OLDER ADULTS.  Author URL.
Gooding K, Casanova F, Cox D, Ball C, Aizawa K, Mawson D, Shore A (2019). Association Between Sural Nerve Conductance Amplitude and Skin Microvascular Responsiveness in Individuals with and without Type 2 Diabetes Across the Subclinical Neuropathy Range.  Author URL.
Meertens RM, Knapp KM, Casanova F, Ball SE, Strain WD (2019). Exploring the potential relationships between microvascular haemodynamics and density in bone: a feasibility study utilising near infrared spectroscopy. UKIO 2019. 10th - 12th Jun 2019.
Meakin PJ, Tuharska Z, Gooding KM, Casanova F, Shore AC, Ashford MLJ, Khan F (2018). Association between β-amyloid, diabetes and endothelial function in humans.  Author URL.
Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Ostling G, Nilsson J, Khan F, Colhoun HM, et al (2018). PARAMETERS DERIVED FROM RESERVOIR PRESSURE ANALYSIS INDEPENDENTLY PREDICT CARDIOVASCULAR EVENTS IN a MULTI-CENTRE STUDY OF INDIVIDUALS WITH TYPE 2 DIABETES.  Author URL.
Ball C, Casanova F, Shore AC, Anning CM, Cox D, Gooding KM (2018). Participant feedback on strategies implemented to maintain participant engagement in a longitudinal, observational clinical study.  Author URL.
Casanova F, Adingupu DD, Gooding KM, Aizawa K, Gates PE, Elyas S, Shore AC, Strain DW (2017). Association Between Renal Function and Matrix Metalloproteinases in Type 2 Diabetes.  Author URL.
Gooding K, Shore AC, Casanova F, Colhoun HM, Looker HC, Leese GP, Agardh E (2017). EXAMINING LONGITUDINAL CHANGES OF MACULAR THICKNESS IN THE EARLY STAGES OF DIABETIC RETINOPATHY.  Author URL.
Gooding K, Mayne T, Casanova F, Ball C, Cox D, Ling R, Shore A (2017). Exploring the Relationship Between Retinal Micro-aneurysms with Plasma Levels of Matrix Metal-loproteinases and Growth Factors in Type 2 Diabetes.  Author URL.
Aizawa K, Casanova F, Mawson DM, Gooding KM, Park CM, Elyas S, Adingupu DD, Strain WD, Parker KH, Gates PE, et al (2017). RESERVOIR-PRESSURE ANALYSIS PREDICTS CARDIOVASCULAR EVENTS IN INDIVIDUALS WITH TYPE 2 DIABETES: a SINGLE-CENTRE STUDY.  Author URL.
Meertens RM, Casanova F, Strain WD, Knapp K, Thorn C (2017). The use of near-infrared systems for investigations of microvascular haemodynamics in human in vivo bone tissue: a systematic review. International Society of Oxygen Transfer to Tissue Annual Meeting 2017. 19th - 23rd Aug 2017.
Meertens R, Knapp K, Strain D, Casanova F (2016). NEAR INFRARED SPECTROSCOPY: a POTENTIAL TOOL FOR ASSESSING HAEMODYNAMIC MARKERS OF THE MICROVASCULAR BLOOD SUPPLY WITHIN BONE TISSUE.  Author URL.
Aizawa K, Casanova F, Mawson D, Elyas S, Adingupu DD, Gooding KM, Strain WD, Park CM, Parker KH, Gates PE, et al (2016). RESERVOIR-PRESSURE ANALYSIS IN TYPE 2 DIABETES INDIVIDUALS WITH CARDIOVASCULAR DISEASE.  Author URL.
Meertens RM, Knapp KM, Strain WD, Casanova F (2016). The use of near infrared spectroscopy (NIRS) as a diagnostic tool to measure microvascular haemodynamics in bone tissue. National Osteoporosis Society 2016. 7th - 9th Nov 2016.
Casanova F, Adingupu D, Gooding K, Strain D, Shore A (2015). DOES GLYCAEMIC CONTROL AFFECT MICROVASCULAR FUNCTION INDEPENDENT OF BLOOD PRESSURE IN TYPE 2 DIABETES?.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Mawson D, Shore AC, Strain WD, Gates PE (2015). PP.20.26.
Gooding KM, Shore AC, Ling R, Casanova F, Looker HC, Agardh E (2015). Regional differences in macular thickness in the early stages of diabetic retinopathy in type 2 diabetes.  Author URL.
Chapman DP, Gooding KM, McDonald TJ, Anning CM, Pamphilon N, Ball C, Casanova F, Shore AC (2015). Using clinical characteristics to account for variation of urinary creatinine excretion improves the accuracy of the albumin to creatinine ratio (ACR) to identify individuals with microalbuminuria.  Author URL.
Clark C, Casanova F, Gooding K, Pamphilon N, Aizawa K, Mawson D, Adingupu D, Ball C, Worthington F, Elyas S, et al (2014). Inter-arm blood pressure difference and differences in arterial stiffness.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Mawson DM, Shore AC, Strain WD, Gates PE (2013). Carotid artery intima-media echogenicity and aortic stiffness in healthy middle-aged and older humans.  Author URL.

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