Erica Burnell
Lecturer (E&S)
E.Burnell@exeter.ac.uk
Publications
Journal articles
France G, Volianskis R, Ingram R, Bannister N, Rothärmel R, Irvine MW, Fang G, Burnell ES, Sapkota K, Costa BM, et al (2022). Differential regulation of STP, LTP and LTD by structurally diverse NMDA receptor subunit-specific positive allosteric modulators. Neuropharmacology, 202 Abstract.
Sapkota K, Burnell ES, Irvine MW, Fang G, Gawande DY, Dravid SM, Jane DE, Monaghan DT (2021). Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792. Neuropharmacology, 201 Abstract.
Wang JX, Irvine MW, Burnell ES, Sapkota K, Thatcher RJ, Li M, Simorowski N, Volianskis A, Collingridge GL, Monaghan DT, et al (2020). Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nature Communications, 11(1). Abstract.
Irvine MW, Fang G, Sapkota K, Burnell ES, Volianskis A, Costa BM, Culley G, Collingridge GL, Monaghan DT, Jane DE, et al (2019). Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid. European Journal of Medicinal Chemistry, 164, 471-498. Abstract.
Burnell ES, Irvine M, Fang G, Sapkota K, Jane DE, Monaghan DT (2019). Positive and Negative Allosteric Modulators of N-Methyl- d -aspartate (NMDA) Receptors: Structure-Activity Relationships and Mechanisms of Action. Journal of Medicinal Chemistry, 62(1), 3-23. Abstract.
Sapkota K, Dore K, Tang K, Irvine M, Fang G, Burnell ES, Malinow R, Jane DE, Monaghan DT (2019). The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators. Biochemical Pharmacology, 159, 140-153. Abstract.
Burnell ES, Irshad AR, Lee ATL, Thomas EJ (2018). Synthetic approaches to phomactins: Late stage stereochemical and reactivity issues. Tetrahedron, 74(47), 6737-6748. Abstract.
Sapkota K, Irvine MW, Fang G, Burnell ES, Bannister N, Volianskis A, Culley GR, Dravid SM, Collingridge GL, Jane DE, et al (2017). Mechanism and properties of positive allosteric modulation of N-methyl-D-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives. Neuropharmacology, 125, 64-79. Abstract.
France G, Fernández-Fernández D, Burnell ES, Irvine MW, Monaghan DT, Jane DE, Bortolotto ZA, Collingridge GL, Volianskis A (2017). Multiple roles of GluN2B-containing NMDA receptors in synaptic plasticity in juvenile hippocampus. Neuropharmacology, 112, 76-83. Abstract.
Lyndon A, Audrey S, Wells C, Burnell ES, Ingle S, Hill R, Hickman M, Henderson G (2017). Risk to heroin users of polydrug use of pregabalin or gabapentin. Addiction, 112(9), 1580-1589. Abstract.
Atherton LA, Burnell ES, Mellor JR (2016). Assessment of methods for the intracellular blockade of GABA<inf>A</inf> receptors. PLoS ONE, 11(8). Abstract.
Broadley KJ, Buffat MGP, Burnell E, Davies RH, Moreau X, Snee S, Thomas EJ (2016). Stereoselective synthesis of oxazolidinonyl-fused piperidines of interest as selective muscarinic (M<inf>1</inf>) receptor agonists: a novel M<inf>1</inf> allosteric modulator. Organic and Biomolecular Chemistry, 14(6), 2057-2089. Abstract.
Broadley KJ, Burnell E, Davies RH, Lee ATL, Snee S, Thomas EJ (2016). The synthesis of a series of adenosine A<inf>3</inf> receptor agonists. Organic and Biomolecular Chemistry, 14(15), 3765-3781. Abstract.
Burnell ES, Irshad AR, Raftery J, Thomas EJ (2015). Approaches to phomactin A: Unexpected late-stage observations. Tetrahedron Letters, 56(23), 3255-3258. Abstract.
Irvine MW, Fang G, Eaves R, Mayo-Martin MB, Burnell ES, Costa BM, Culley GR, Volianskis A, Collingridge GL, Monaghan DT, et al (2015). Synthesis of a series of novel 3,9-disubstituted phenanthrenes as analogues of known N-methyl-D-aspartate receptor allosteric modulators. Synthesis (Germany), 47(11), 1593-1610. Abstract.
Chapters
Burnell ES (2020). Chapter 10 Drugs targeting mitochondrial functions. In (Ed) Antimalarial Agents, Elsevier, 375-402.
Burnell ES (2020). Drugs targeting mitochondrial functions. In (Ed) Antimalarial Agents: Design and Mechanism of Action, 375-402. Abstract.
