Loading content
Dr Clare Gallon BSc(Hons) PhD FHEA

Dr Clare Gallon BSc(Hons) PhD FHEA

Senior Lecturer in Biomedical Sciences (Education & Scholarship)

2957

01392722957

Medical School Building G04

Clare joined the Medical School in November 2011 and is involved in teaching on the Medicine and Medical Sciences programmes and is discipline co-lead for Biochemistry and Cell Biology.  She is the programme lead for Sport and Exercise Medical Sciences, module lead for the core 2nd year Medical Sciences module, Integrated Clinical Science 2, and is a Senior Personal Tutor. Clare is also the academic lead for Open and Offer Holder Days and the year 2 Lead Academic Tutor for the Medical Sciences Programme.

Qualifications

2001 BSc(Hons) Medical Biochemistry, University of Birmingham

2005 PhD Biochemistry, University of Birmingham

2013 PCAP - Postgraduate Certificate in Academic Practice, University of Exeter

2014 FHEA - Fellow of the Higher Education Academy

Career

Before joining the Medical School,  Clare was involved in cardiovascular science research, with a particular focus on the molecular mechanisms of cardiac muscle contractile regulation.  After undertaking her undergraduate dissertation project and PhD in this field she was a postdoctoral researcher in cardiovascular research laboratories in the College of Veterinary Medicine, Washington State University, Pullman, USA (2004-2006), the National Heart and Lung Insitute, Imperial College London (2006-2008), the Research Department of Metabolism and Experimental Therapeutics, University College London (2008-2009) and the MRC Clinical Sciences Centre, Imperial College London (2009-2011).

Research

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Bayliss CR, Jacques AM, Leung M-C, Ward DG, Redwood CS, Gallon CE, Copeland O, McKenna WJ, Dos Remedios C, Marston SB, et al (2013). Myofibrillar Ca(2+) sensitivity is uncoupled from troponin I phosphorylation in hypertrophic obstructive cardiomyopathy due to abnormal troponin T. Cardiovasc Res, 97(3), 500-508. Abstract.  Author URL.
Gollapudi SK, Gallon CE, Chandra M (2013). The tropomyosin binding region of cardiac troponin T modulates crossbridge recruitment dynamics in rat cardiac muscle fibers. Journal of Molecular Biology, 425(9), 1565-1581. Abstract.
Dyer EC, Jacques AM, Hoskins AC, Ward DG, Gallon CE, Messer AE, Kaski JP, Burch M, Kentish JC, Marston SB, et al (2009). Functional analysis of a unique troponin c mutation, GLY159ASP, that causes familial dilated cardiomyopathy, studied in explanted heart muscle. Circ Heart Fail, 2(5), 456-464. Abstract.  Author URL.
Messer AE, Gallon CE, McKenna WJ, Dos Remedios CG, Marston SB (2009). The use of phosphate-affinity SDS-PAGE to measure the cardiac troponin I phosphorylation site distribution in human heart muscle. Proteomics Clin Appl, 3(12), 1371-1382. Abstract.  Author URL.
Gallon CE (2008). Current techniques for the study of troponin I phosphorylation in human heart. J Muscle Res Cell Motil, 29(6-8), 169-172. Abstract.  Author URL.
Jacques AM, Copeland O, Messer AE, Gallon CE, King K, McKenna WJ, Tsang VT, Marston SB (2008). Myosin binding protein C phosphorylation in normal, hypertrophic and failing human heart muscle. J Mol Cell Cardiol, 45(2), 209-216. Abstract.  Author URL.
Jacques AM, Briceno N, Messer AE, Gallon CE, Jalilzadeh S, Garcia E, Kikonda-Kanda G, Goddard J, Harding SE, Watkins H, et al (2008). The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy. Cardiovasc Res, 79(3), 481-491. Abstract.  Author URL.
Gallon CE (2008). Troponin C. Alias: Contractile calcium switch. Calcium Binding Proteins, 3(1).
Gallon CE, Tschirgi ML, Chandra M (2006). Differences in myofilament calcium sensitivity in rat psoas fibers reconstituted with troponin T isoforms containing the alpha- and beta-exons. Arch Biochem Biophys, 456(2), 127-134. Abstract.  Author URL.
Patchell VB, Gallon CE, Evans JS, Gao Y, Perry SV, Levine BA (2005). The regulatory effects of tropomyosin and troponin-I on the interaction of myosin loop regions with F-actin. J Biol Chem, 280(15), 14469-14475. Abstract.  Author URL.
Ward DG, Brewer SM, Calvert MJ, Gallon CE, Gao Y, Trayer IP (2004). Characterization of the interaction between the N-terminal extension of human cardiac troponin I and troponin C. BIOCHEMISTRY, 43(13), 4020-4027. Author URL.
Ward DG, Brewer SM, Calvert MJ, Gallon CE, Gao Y, Trayer IP (2004). Characterization of the interaction between the N-terminal extension of human cardiac troponin I and troponin C. Biochemistry, 43(13), 4020-4027. Abstract.  Author URL.
Ward DG, Brewer SM, Gallon CE, Gao Y, Levine BA, Trayer IP (2004). NMR and mutagenesis studies on the phosphorylation region of human cardiac troponin I. Biochemistry, 43(19), 5772-5781. Abstract.  Author URL.
Patchell VB, Gallon CE, Hodgkin MA, Fattoum A, Perry SV, Levine BA (2002). The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin. Eur J Biochem, 269(20), 5088-5100. Abstract.  Author URL.

Conferences

Marston SB, Messer AE, Gallon CE, Sancho-Sollis R, Walker JW (2010). DETERMINATION OF TROPONIN I PHOSPHORYLATION SITES IN HUMAN HEART MUSCLE.  Author URL.
Bayliss CR, Messer AE, Copeland O, Gallon CE, Marston SB (2010). THIN FILAMENTS RECONSTITUTED WITH TROPONIN EXTRACTED FROM PATIENTS WITH HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY ARE FUNCTIONALLY ABNORMAL.  Author URL.
Garcia EA, Kanda GK, Lyon A, Gallon CE, Messer AE, O'Gara P, Marston SB, Harding SE (2008). Tonic support of contraction involving the PI3 kinase pathway in ventricular myocytes from failing human heart.  Author URL.
Jacques AM, Messer AE, Gallon CE, Tsang V, McKenna WJ, Marston SB (2007). A comparison between TnT, TnI, MyBP-C and MLC-2 phosphorylation in tissue from septal myectomies of hypertrophic obstructive cardiomyopathy patients and donor hearts.  Author URL.

Publications by year


2013

Bayliss CR, Jacques AM, Leung M-C, Ward DG, Redwood CS, Gallon CE, Copeland O, McKenna WJ, Dos Remedios C, Marston SB, et al (2013). Myofibrillar Ca(2+) sensitivity is uncoupled from troponin I phosphorylation in hypertrophic obstructive cardiomyopathy due to abnormal troponin T. Cardiovasc Res, 97(3), 500-508. Abstract.  Author URL.
Gollapudi SK, Gallon CE, Chandra M (2013). The tropomyosin binding region of cardiac troponin T modulates crossbridge recruitment dynamics in rat cardiac muscle fibers. Journal of Molecular Biology, 425(9), 1565-1581. Abstract.

2010

Marston SB, Messer AE, Gallon CE, Sancho-Sollis R, Walker JW (2010). DETERMINATION OF TROPONIN I PHOSPHORYLATION SITES IN HUMAN HEART MUSCLE.  Author URL.
Bayliss CR, Messer AE, Copeland O, Gallon CE, Marston SB (2010). THIN FILAMENTS RECONSTITUTED WITH TROPONIN EXTRACTED FROM PATIENTS WITH HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY ARE FUNCTIONALLY ABNORMAL.  Author URL.

2009

Dyer EC, Jacques AM, Hoskins AC, Ward DG, Gallon CE, Messer AE, Kaski JP, Burch M, Kentish JC, Marston SB, et al (2009). Functional analysis of a unique troponin c mutation, GLY159ASP, that causes familial dilated cardiomyopathy, studied in explanted heart muscle. Circ Heart Fail, 2(5), 456-464. Abstract.  Author URL.
Messer AE, Gallon CE, McKenna WJ, Dos Remedios CG, Marston SB (2009). The use of phosphate-affinity SDS-PAGE to measure the cardiac troponin I phosphorylation site distribution in human heart muscle. Proteomics Clin Appl, 3(12), 1371-1382. Abstract.  Author URL.

2008

Gallon CE (2008). Current techniques for the study of troponin I phosphorylation in human heart. J Muscle Res Cell Motil, 29(6-8), 169-172. Abstract.  Author URL.
Jacques AM, Copeland O, Messer AE, Gallon CE, King K, McKenna WJ, Tsang VT, Marston SB (2008). Myosin binding protein C phosphorylation in normal, hypertrophic and failing human heart muscle. J Mol Cell Cardiol, 45(2), 209-216. Abstract.  Author URL.
Jacques AM, Briceno N, Messer AE, Gallon CE, Jalilzadeh S, Garcia E, Kikonda-Kanda G, Goddard J, Harding SE, Watkins H, et al (2008). The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy. Cardiovasc Res, 79(3), 481-491. Abstract.  Author URL.
Garcia EA, Kanda GK, Lyon A, Gallon CE, Messer AE, O'Gara P, Marston SB, Harding SE (2008). Tonic support of contraction involving the PI3 kinase pathway in ventricular myocytes from failing human heart.  Author URL.
Gallon CE (2008). Troponin C. Alias: Contractile calcium switch. Calcium Binding Proteins, 3(1).

2007

Jacques AM, Messer AE, Gallon CE, Tsang V, McKenna WJ, Marston SB (2007). A comparison between TnT, TnI, MyBP-C and MLC-2 phosphorylation in tissue from septal myectomies of hypertrophic obstructive cardiomyopathy patients and donor hearts.  Author URL.

2006

Gallon CE, Tschirgi ML, Chandra M (2006). Differences in myofilament calcium sensitivity in rat psoas fibers reconstituted with troponin T isoforms containing the alpha- and beta-exons. Arch Biochem Biophys, 456(2), 127-134. Abstract.  Author URL.

2005

Patchell VB, Gallon CE, Evans JS, Gao Y, Perry SV, Levine BA (2005). The regulatory effects of tropomyosin and troponin-I on the interaction of myosin loop regions with F-actin. J Biol Chem, 280(15), 14469-14475. Abstract.  Author URL.

2004

Ward DG, Brewer SM, Calvert MJ, Gallon CE, Gao Y, Trayer IP (2004). Characterization of the interaction between the N-terminal extension of human cardiac troponin I and troponin C. BIOCHEMISTRY, 43(13), 4020-4027. Author URL.
Ward DG, Brewer SM, Calvert MJ, Gallon CE, Gao Y, Trayer IP (2004). Characterization of the interaction between the N-terminal extension of human cardiac troponin I and troponin C. Biochemistry, 43(13), 4020-4027. Abstract.  Author URL.
Ward DG, Brewer SM, Gallon CE, Gao Y, Levine BA, Trayer IP (2004). NMR and mutagenesis studies on the phosphorylation region of human cardiac troponin I. Biochemistry, 43(19), 5772-5781. Abstract.  Author URL.

2002

Patchell VB, Gallon CE, Hodgkin MA, Fattoum A, Perry SV, Levine BA (2002). The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin. Eur J Biochem, 269(20), 5088-5100. Abstract.  Author URL.

 Cardiovascular science, small group problem based learning and academic tutoring in Medical Sciences.

Back | Edit Profile