University of Exeter Medical School

Dr. Barry Chioza

Dr. Barry Chioza

Postdoctoral Research Fellow

 B.A.Chioza@exeter.ac.uk

 01392 406754

 RILD Building L3/24 RILD South

 

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Overview

Barry Chioza is a Research Fellow working at the University of Exeter Medical School. Barry obtained an Honours degree in Biochemistry from Aberystwyth University before going to King’s College London to complete a M.Sc. in Neuroscience, followed by a Ph.D. in Molecular Genetics. His project aimed to identify variants in candidate genes for idiopathic generalised epilepsy (IGE) that have been previously identified to be involved in Mendelian idiopathic epilepsies in humans or mouse models using case-control and within-family association studies.

After completion of his Ph.D. Barry worked within leading research groups at the University College London, St George’s University of London and the University of Exeter.

Qualifications

  • PhD
  • MSc. Neuroscience
  • BSc.(Hons) Biochemistry

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Research

Research interests

Barry joined the Complex Disease Epigenetics Group in January 2018 to work on the MRC project investigating regulatory genomic variation associated with schizophrenia in human neuronal nuclei

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Publications

Journal articles

Hannon E, Mill J, Dempster E, Walker E, Franklin A, Chioza B, Commins G, Davies J, Burrage J (2024). Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles. BMC Biology
Mill J, Hannon E, Dempster E, Franklin A, Burrage J, Davies J, Chioza B, Commin G, Jeffries AR, Bamford RA, et al (2023). W76. CELL-SPECIFIC METHYLOMIC VARIATION IN NEURODEVELOPMENT AND SCHIZOPHRENIA. European Neuropsychopharmacology, 75, s144-s145.
Davies J, Franklin A, Walker E, Owens N, Bray N, Bamford RA, Commin G, Chioza B, Burrage J, Dempster E, et al (2022). 1. DEVELOPMENTAL TRAJECTORIES OF DNA METHYLATION IN NEURAL CELL POPULATIONS IN HUMAN CORTEX AND LINKS TO NEURODEVELOPMENTAL DISORDERS. European Neuropsychopharmacology, 63
Hannon E, Davies J, Chioza B, Policicchio S, Burrage J, Commin G, Jeffries AR, Schalkwyk L, Dempster E, Mill J, et al (2022). 89. IDENTIFYING CELL-TYPE-SPECIFIC EPIGENETIC VARIATION IN THE CORTEX ASSOCIATED WITH SCHIZOPHRENIA. European Neuropsychopharmacology, 63, e93-e94.
Shireby G, Dempster EL, Policicchio S, Smith RG, Pishva E, Chioza B, Davies JP, Burrage J, Lunnon K, Seiler Vellame D, et al (2022). DNA methylation signatures of Alzheimer’s disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types. Nature Communications, 13(1). Abstract.
Fasham J, Lin S, Ghosh P, Radio FC, Farrow EG, Thiffault I, Kussman J, Zhou D, Hemming R, Zahka K, et al (2022). Elucidating the clinical spectrum and molecular basis of HYAL2 deficiency. Genet Med, 24(3), 631-644. Abstract.  Author URL.
Bademci G, Lachgar-Ruiz M, Deokar M, Zafeer MF, Abad C, Yildirim Baylan M, Ingham NJ, Chen J, Sineni CJ, Vadgama N, et al (2022). Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice. Proc Natl Acad Sci U S A, 119(26). Abstract.  Author URL.
Ammous Z, Rawlins LE, Jones H, Leslie JS, Wenger O, Scott E, Deline J, Herr T, Evans R, Scheid A, et al (2021). A biallelic SNIP1 Amish founder variant causes a recognizable neurodevelopmental disorder. PLOS Genetics, 17(9), e1009803-e1009803. Abstract.
Khan K, Mehmood S, Liu C, Siddiqui M, Ahmad A, Faiz BY, Chioza BA, Baple EA, Ullah MI, Akram Z, et al (2021). A recurrent rare intronic variant in <scp><i>CAPN3</i></scp> alters <scp>mRNA</scp> splicing and causes autosomal recessive limb‐girdle muscular dystrophy‐1 in three Pakistani pedigrees. American Journal of Medical Genetics Part A, 188(2), 498-508. Abstract.
Salter CG, Cai Y, Lo B, Helman G, Taylor H, McCartney A, Leslie JS, Accogli A, Zara F, Traverso M, et al (2021). Biallelic PI4KA variants cause neurological, intestinal and immunological disease. Brain, 144(12), 3597-3610. Abstract.  Author URL.
Mehmood S, Harlalka GV, Dad R, Chioza BA, Ullah MI, Ahmad A, Crosby AH, Baple EL, Hassan MJ (2021). In Silico analysis of SIGMAR1 gene causing distal hereditary motor neuropathy in a Pakistani family (vol 16C, 100445, 2019). GENE REPORTS, 24  Author URL.
Leslie JS, Rawlins LE, Chioza BA, Olubodun OR, Salter CG, Fasham J, Jones HF, Cross HE, Lam S, Harlalka GV, et al (2020). MNS1 variant associated with situs inversus and male infertility. Eur J Hum Genet, 28(1), 50-55. Abstract.  Author URL.
Rawlins LE, Jones H, Wenger O, Aye M, Fasham J, Harlalka GV, Chioza BA, Miron A, Ellard S, Wakeling M, et al (2019). An Amish founder variant consolidates disruption of CEP55 as a cause of hydranencephaly and renal dysplasia. Eur J Hum Genet, 27(4), 657-662. Abstract.  Author URL.
Alakbarzade V, Iype T, Chioza BA, Singh R, Harlalka GV, Hardy H, Sreekantan-Nair A, Proukakis C, Peall K, Clark LN, et al (2019). Copy number variation of <i>LINGO1</i> in familial dystonic tremor. Neurology. Genetics, 5(1). Abstract.
Jeffries AR, Maroofian R, Salter CG, Chioza BA, Cross HE, Patton MA, Dempster E, Temple IK, Mackay DJG, Rezwan FI, et al (2019). Growth disrupting mutations in epigenetic regulatory molecules are associated with abnormalities of epigenetic aging. Genome research, 29(7), 1057-1066. Abstract.
Mehmood S, Harlalka GV, Dad R, Chioza BA, Ullah MI, Ahmad A, Crosby AH, Baple EL, Hassan MJ (2019). In Silico analysis of SIGMAR1 gene causing distal hereditary motor neuropathy in a Pakistani family. Gene Reports, 16 Abstract.
Ullah MI, Nasir A, Ahmad A, Harlalka GV, Ahmad W, Hassan MJ, Baple EL, Crosby AH, Chioza BA (2018). Identification of novel L2HGDH mutation in a large consanguineous Pakistani family- a case report. BMC Med Genet, 19(1). Abstract.  Author URL.
Li L, Jiao X, D'Atri I, Ono F, Nelson R, Chan C-C, Nakaya N, Ma Z, Ma Y, Cai X, et al (2018). Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa. PLoS Genet, 14(8). Abstract.  Author URL.
Arshad MW, Harlalka GV, Lin S, D'Atri I, Mehmood S, Shakil M, Hassan MJ, Chioza BA, Self JE, Ennis S, et al (2018). Mutations in TYR and OCA2 associated with oculocutaneous albinism in Pakistani families. Meta Gene, 17, 48-55. Abstract.
Salter CG, Beijer D, Hardy H, Barwick KES, Bower M, Mademan I, De Jonghe P, Deconinck T, Russell MA, McEntagart MM, et al (2018). Truncating SLC5A7 mutations underlie a spectrum of dominant hereditary motor neuropathies. Neurol Genet, 4(2). Abstract.  Author URL.
Ahmed MY, Al-Khayat A, Al-Murshedi F, Al-Futaisi A, Chioza BA, Pedro Fernandez-Murray J, Self JE, Salter CG, Harlalka GV, Rawlins LE, et al (2017). A mutation of EPT1 (SELENOI) underlies a new disorder of Kennedy pathway phospholipid biosynthesis. Brain, 140(3), 547-554. Abstract.  Author URL.
Everett KV, Ataliotis P, Chioza BA, Shaw-Smith C, Chung EMK (2017). A novel missense mutation in the transcription factor FOXF1 cosegregating with infantile hypertrophic pyloric stenosis in the extended pedigree linked to IHPS5 on chromosome 16q24. Pediatr Res, 81(4), 632-638. Abstract.  Author URL.
Wang H, Salter CG, Refai O, Hardy H, Barwick KES, Akpulat U, Kvarnung M, Chioza BA, Harlalka G, Taylan F, et al (2017). Choline transporter mutations in severe congenital myasthenic syndrome disrupt transporter localization. Brain, 140(11), 2838-2850. Abstract.  Author URL.
Muggenthaler MMA, Chowdhury B, Hasan SN, Cross HE, Mark B, Harlalka GV, Patton MA, Ishida M, Behr ER, Sharma S, et al (2017). Mutations in HYAL2, Encoding Hyaluronidase 2, Cause a Syndrome of Orofacial Clefting and Cor Triatriatum Sinister in Humans and Mice. PLoS Genet, 13(1). Abstract.  Author URL.
Zollo M, Ahmed M, Ferrucci V, Salpietro V, Asadzadeh F, Carotenuto M, Maroofian R, Al-Amri A, Singh R, Scognamiglio I, et al (2017). PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment. Brain, 140(4), 940-952. Abstract.  Author URL.
Dehghan Tezerjani M, Maroofian R, Vahidi Mehrjardi MY, Chioza BA, Zamaninejad S, Kalantar SM, Nori-Shadkam M, Ghadimi H, Baple EL, Crosby AH, et al (2016). A novel mutation in the OFD1 gene in a family with oral-facial-digital syndrome type 1: a case report. Iranian Journal of Public Health, 45(10), 1359-1366. Abstract.
Vona B, Hofrichter MAH, Chioza BA, Crosby AH, Nanda I, Haaf T (2016). Genetic elucidation of nonsyndromic hearing loss in the high-throughput sequencing era. Monographs in Human Genetics, 20, 56-72. Abstract.
Alves MM, Halim D, Maroofian R, de Graaf BM, Rooman R, van der Werf CS, Van de Vijver E, Mehrjardi MY, Aflatoonian M, Chioza BA, et al (2016). Genetic screening of Congenital Short Bowel Syndrome patients confirms CLMP as the major gene involved in the recessive form of this disorder. Eur J Hum Genet, 24(11), 1627-1629. Abstract.  Author URL.
Harlalka GV, McEntagart ME, Gupta N, Skrzypiec AE, Mucha MW, Chioza BA, Simpson MA, Sreekantan-Nair A, Pereira A, Günther S, et al (2016). Novel Genetic, Clinical, and Pathomechanistic Insights into TFG-Associated Hereditary Spastic Paraplegia. Hum Mutat, 37(11), 1157-1161. Abstract.  Author URL.
Aharoni S, Barwick KES, Harlalka GV, Straussberg R, Nevo Y, Chioza BA, McEntagart MM, Mimouni-Bloch A, Weedon M, Crosby AH, et al (2016). Novel homozygous missense mutation in GAN associated with Charcot-Marie-Toothdisease type 2 in a large consanguineousfamily from Israel. BMC Medical Genetics, 17, 18-18.
Iype T, Alakbarzade V, Iype M, Singh R, Sreekantan-Nair A, Chioza BA, Mohapatra TM, Baple EL, Patton MA, Warner TT, et al (2015). A large Indian family with rearrangement of chromosome 4p16 and 3p26.3 and divergent clinical presentations. BMC Med Genet, 16 Abstract.  Author URL.
Alakbarzade V, Hameed A, Quek DQY, Chioza BA, Baple EL, Cazenave-Gassiot A, Nguyen LN, Wenk MR, Ahmad AQ, Sreekantan-Nair A, et al (2015). A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome. Nature Genetics, 47(7), 814-817. Abstract.
Alakbarzade V, Hameed A, Quek DQY, Chioza BA, Baple EL, Cazenave-Gassiot A, Nguyen LN, Wenk MR, Ahmad AQ, Sreekantan-Nair A, et al (2015). A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome. Nat Genet, 47(7), 814-817. Abstract.  Author URL.
Ahmed MY, Chioza BA, Rajab A, Schmitz-Abe K, Al-Khayat A, Al-Turki S, Baple EL, Patton MA, Al-Memar AY, Hurles ME, et al (2015). Loss of PCLO function underlies pontocerebellar hypoplasia type III. Neurology, 84(17), 1745-1750. Abstract.  Author URL.
Jinks RN, Puffenberger EG, Baple EL, Harding B, Fogo AB, Wenger O, Xin B, Koehler AE, McGlincy MH, Provencher MM, et al (2015). Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73. Brain Abstract.
Hanson HL, Wilson MJ, Short JP, Chioza BA, Crosby AH, Nash RM, Marks KJ, Mansour S (2014). Germline CBL mutation associated with a noonan-like syndrome with primary lymphedema and teratoma associated with acquired uniparental isodisomy of chromosome 11q23. American Journal of Medical Genetics, Part A, 164(4), 1003-1009. Abstract.
Hanson HL, Wilson MJ, Short JP, Chioza BA, Crosby AH, Nash RM, Marks KJ, Mansour S (2014). Germline CBL mutation associated with a noonan-like syndrome with primary lymphedema and teratoma associated with acquired uniparental isodisomy of chromosome 11q23. Am J Med Genet A, 164A(4), 1003-1009. Abstract.  Author URL.
Baple EL, Chambers H, Cross HE, Fawcett H, Nakazawa Y, Chioza BA, Harlalka GV, Mansour S, Sreekantan-Nair A, Patton MA, et al (2014). Hypomorphic PCNA mutation underlies a human DNA repair disorder. J Clin Invest, 124(7), 3137-3146. Abstract.  Author URL.
Baple EL, Maroofian R, Chioza BA, Izadi M, Cross HE, Al-Turki S, Barwick K, Skrzypiec A, Pawlak R, Wagner K, et al (2014). Mutations in KPTN cause macrocephaly, neurodevelopmental delay, and seizures. Am J Hum Genet, 94(1), 87-94. Abstract.  Author URL.
Faundes V, Castillo-Taucher S, Gonzalez-Hormazabal P, Chandler K, Crosby A, Chioza B (2014). Raine syndrome: an overview. European Journal of Medical Genetics, 57(9), 536-542. Abstract.
Faundes V, Castillo-Taucher S, Gonzalez-Hormazabal P, Chandler K, Crosby A, Chioza B (2014). Raine syndrome: an overview. Eur J Med Genet, 57(9), 536-542. Abstract.  Author URL.
Sharifi R, Morra R, Appel CD, Tallis M, Chioza B, Jankevicius G, Simpson MA, Matic I, Ozkan E, Golia B, et al (2013). Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease. EMBO J, 32(9), 1225-1237. Abstract.  Author URL.
Harlalka GV, Baple EL, Cross H, Kühnle S, Cubillos-Rojas M, Matentzoglu K, Patton MA, Wagner K, Coblentz R, Ford DL, et al (2013). Mutation of HERC2 causes developmental delay with Angelman-like features. J Med Genet, 50(2), 65-73. Abstract.  Author URL.
Harlalka GV, Lehman A, Chioza B, Baple EL, Maroofian R, Cross HE, Sreekantan-Nair A, Priestman C, Royle L, Kozak RP, et al (2013). Mutations in B4GALNT1 (GM2 Synthase) underlie a new disorder of ganglioside biosynthesis. Brain, 136(12), 3618-3624. Abstract.  Author URL.
Tekin M, Chioza BA, Matsumoto Y, Diaz-Horta O, Cross HE, Duman D, Kokotas H, Moore-Barton HL, Sakoori K, Ota M, et al (2013). SLITRK6 mutations cause myopia and deafness in humans and mice. Journal of Clinical Investigation, 123(5), 2094-2102.
Barwick KES, Wright J, Al-Turki S, McEntagart MM, Nair A, Chioza B, Al-Memar A, Modarres H, Reilly MM, Dick KJ, et al (2012). Defective presynaptic choline transport underlies hereditary motor neuropathy. Am J Hum Genet, 91(6), 1103-1107. Abstract.  Author URL.
Christos P, Patel H, Chioza BA, Dick K, Al-Memar A, Chrzanowksa-Lightowlers ZMA, Cross H, Patton MA, Lightowlers RN, Crosby AH, et al (2011). 07 Defective mitochondrial mRNA maturation is associated with spastic ataxia. Journal of Neurology, Neurosurgery & Psychiatry, 82(3), e1-e1.
Crosby AH, Patel H, Chioza BA, Proukakis C, Gurtz K, Patton MA, Sharifi R, Harlalka G, Simpson MA, Dick K, et al (2010). Defective mitochondrial mRNA maturation is associated with spastic ataxia. American Journal Human Genetics, 87(5), 655-660. Abstract.  Author URL.
Reish O, Slatkin M, Chapman-Shimshoni D, Elizur A, Chioza B, Castleman V, Mitchison HM (2010). Founder mutation(s) in the RSPH9 gene leading to primary ciliary dyskinesia in two inbred Bedouin families. Ann Hum Genet, 74(2), 117-125. Abstract.  Author URL.
Chioza BA, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dooley JM, Dulac O, Durner M, Eeg-Olofsson O, et al (2009). Genome wide high density SNP-based linkage analysis of childhood absence epilepsy identifies a susceptibility locus on chromosome 3p23-p14. Epilepsy Res, 87(2-3), 247-255. Abstract.  Author URL.
Everett KV, Chioza BA, Georgoula C, Reece A, Gardiner RM, Chung EMK (2009). Infantile hypertrophic pyloric stenosis: evaluation of three positional candidate genes, TRPC1, TRPC5 and TRPC6, by association analysis and re-sequencing. Hum Genet, 126(6), 819-831. Abstract.  Author URL.
Everett K, Chioza B, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dulac O, Eeg-Olofsson O, Feucht M, et al (2008). Erratum: Linkage and association analysis of CACNG3 in childhood absence epilepsy (European Journal of Human Genetics (2007) vol. 15 (463-472) 10.1039/sj.ejhg.5201783). European Journal of Human Genetics, 16(5), 659-660.
Everett KV, Chioza BA, Georgoula C, Reece A, Capon F, Parker KA, Cord-Udy C, McKeigue P, Mitton S, Pierro A, et al (2008). Genome-wide high-density SNP-based linkage analysis of infantile hypertrophic pyloric stenosis identifies loci on chromosomes 11q14-q22 and Xq23. Am J Hum Genet, 82(3), 756-762. Abstract.  Author URL.
Everett K, Chioza B, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dulac O, Eeg-Olofsson O, Feucht M, et al (2008). Linkage and association analysis of CACNG3 in childhood absence epilepsy (vol 15, pg 463, 2007). EUROPEAN JOURNAL OF HUMAN GENETICS, 16(5), 659-660.  Author URL.
Everett KV, Capon F, Georgoula C, Chioza BA, Reece A, Jaswon M, Pierro A, Puri P, Gardiner RM, Chung EM, et al (2008). Linkage of monogenic infantile hypertrophic pyloric stenosis to chromosome 16q24. Eur J Hum Genet, 16(9), 1151-1154. Abstract.  Author URL.
Everett KV, Chioza B, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dulac O, Eeg-Olofsson O, Feucht M, et al (2007). Linkage and association analysis of CACNG3 in childhood absence epilepsy. Eur J Hum Genet, 15(4), 463-472. Abstract.  Author URL.
Everett K, Chioza B, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dooley J, Dulac O, Durner M, et al (2007). Linkage and mutational analysis of CLCN2 in childhood absence epilepsy. Epilepsy Res, 75(2-3), 145-153. Abstract.  Author URL.
Chioza B, Everett K, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dulac O, Durner M, Eeg-Olofsson O, Feucht M, et al (2006). Evaluation of CACNA1H in European patients with childhood absence epilepsy. Epilepsy Res, 69(2), 177-181. Abstract.  Author URL.
Nashef L, Blower J, Chioza BA, Goodwin HJ, McCormick D, Asherson P, Makoff AJ (2002). 4. Genetic association studies of idiopathic generalized epilepsy. Acta Neurologica Scandinavica, 102, 5-52.
Wilkie H, Osei-Lah A, Chioza B, Nashef L, McCormick D, Asherson P, Makoff AJ (2002). Association of mu-opioid receptor subunit gene and idiopathic generalized epilepsy. Neurology, 59(5), 724-728. Abstract.  Author URL.
Chioza B, Nashef L, Asherson P, Makoff A (2002). CACNA1A and P/Q-type calcium channels in epilepsy. Lancet, 359(9302).  Author URL.
Chioza B, Osei-Lah A, Nashef L, Suarez-Merino B, Wilkie H, Sham P, Knight J, Asherson P, Makoff AJ (2002). Haplotype and linkage disequilibrium analysis to characterise a region in the calcium channel gene CACNA1A associated with idiopathic generalised epilepsy. Eur J Hum Genet, 10(12), 857-864. Abstract.  Author URL.
Chioza B, Osei-Lah A, Wilkie H, Nashef L, McCormick D, Asherson P, Makoff AJ (2002). Suggestive evidence for association of two potassium channel genes with different idiopathic generalised epilepsy syndromes. Epilepsy Res, 52(2), 107-116. Abstract.  Author URL.
Chioza B, Wilkie H, Nashef L, Blower J, McCormick D, Sham P, Asherson P, Makoff AJ (2001). Association between the alpha(1a) calcium channel gene CACNA1A and idiopathic generalized epilepsy. Neurology, 56(9), 1245-1246.  Author URL.
Chioza BA, Ujfalusy A, Csiszar K, Leigh PN, Powell JF, Radunović A (2001). Mutations in the lysyl oxidase gene are not associated with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord, 2(2), 93-97. Abstract.  Author URL.
Chioza B, Goodwin H, Blower J, McCormick D, Nashef L, Asherson P, Makoff AJ (2000). Failure to replicate association between the gene for the neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) and IGE. Am J Med Genet, 96(6), 814-816. Abstract.  Author URL.
Goodwin H, Curran N, Chioza B, Blower J, Nashef L, Asherson P, Makoff AJ (2000). No association found between polymorphisms in genes encoding mGluR7 and mGluR8 and idiopathic generalised epilepsy in a case control study. Epilepsy Res, 39(1), 27-31. Abstract.  Author URL.
Al-Chalabi A, Andersen PM, Nilsson P, Chioza B, Andersson JL, Russ C, Shaw CE, Powell JF, Leigh PN (1999). Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis. Hum Mol Genet, 8(2), 157-164. Abstract.  Author URL.
Makoff A, Chioza B, Curran N, Asherson P, Nashef L (1998). Association study of idiopathic primary generalized epilepsy (IGE). Seizure, 7(5).
Shaw CE, Enayat ZE, Chioza BA, Al-Chalabi A, Radunovic A, Powell JF, Leigh PN (1998). Mutations in all five exons of SOD-1 may cause ALS. Ann Neurol, 43(3), 390-394. Abstract.  Author URL.
Al-Chalabi A, Andersen PM, Chioza B, Shaw C, Sham PC, Robberecht W, Matthijs G, Camu W, Marklund SL, Forsgren L, et al (1998). Recessive amyotrophic lateral sclerosis families with the D90A SOD1 mutation share a common founder: evidence for a linked protective factor. Hum Mol Genet, 7(13), 2045-2050. Abstract.  Author URL.
Shaikh S, Collier D, Chioza B, Li T, Lui X, Kerwin R (1997). A linkage disequilibrium study of chromosome 4p16 and schizophrenia. Schizophrenia Research, 24(1-2), 53-53.
Jackson M, Al-Chalabi A, Enayat ZE, Chioza B, Leigh PN, Morrison KE (1997). Copper/zinc superoxide dismutase 1 and sporadic amyotrophic lateral sclerosis: analysis of 155 cases and identification of a novel insertion mutation. Ann Neurol, 42(5), 803-807. Abstract.  Author URL.

Conferences

Leslie J, Rawlins LE, Chioza BA, Olusanya OR, Salter CG, Fasham J, Cross HE, Lam S, Harlalka GV, Muggenthaler MMA, et al (2022). <i>MNS1</i> gene alterations are associated with situs inversus and male infertility.  Author URL.
Davies J, Franklin A, Commin G, Walker E, Policicchio S, Jeffries A, Burrage J, Chioza B, Liu J, Bray N, et al (2021). CELL-TYPE-SPECIFIC PATTERNS OF DNA METHYLATION IN THE DEVELOPING HUMAN BRAIN.  Author URL.
D'Atri I, Li L, Jiao X, Ono F, Nelson R, Chan C, Nakaya N, Ma Z, Ma Y, Cai X, et al (2019). Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa.  Author URL.
D'Atri I, Li L, Jiao X, Ono F, Nelson R, Chan C, Nakaya N, Ma Z, Ma Y, Cai X, et al (2019). Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa.  Author URL.
Muggenthaler M, Zahka K, Lever H, Desai M, Chioza BA, Cross H, Behr ER, Sharma S, Crosby AH (2015). Phenotypic variation of hypertrophic cardiomyopathy caused by the 3330+2T&gt;G mutation in myosin binding protein-C in 303 Amish individuals.  Author URL.
Baple E, Cross H, Chioza B, Simpson M, Trembath R, McEntagart M, Patton M, Crosby A (2011). A founder mutation in the SAMHD1 gene identified in the Amish is associated with laryngeal involvement.  Author URL.
Moore-Barton H, Chioza BA, Matsumoto Y, Cross HE, Sakoori K, Ota M, Gurtz K, Patton MA, Aruga J, Crosby AH, et al (2011). Molecular and pathological characterisation of an inherited condition amongst the Amish involving high myopia and sensorineural hearing loss.  Author URL.
Everett K, Chioza B, Sharp R, Mckeigue P, Robinson R, Taske N, Rees M, Gardiner RM (2006). Absence epilepsy:: linkage and association analysis of <i>CACNG3</i>.  Author URL.
Everett K, Chioza B, Robinson R, Rees M, Gardiner RM (2005). A missense single nucleotide polymorphism (RS2228292, E718D) in CLCN2 associated with absence epilepsy.  Author URL.
Chioza B, Everett K, Robinson R, Taske N, Rees M, Gardiner RM (2005). Absence epilepsy: Evaluation of linkage disequilibrium and allelic association in GABRB3, GABRA5, and GABRG3 on chromosome 15Q11-13.  Author URL.
Chioza BA, Everett KV, Sharp R, McKeigue P, Robinson R, Taske N, Rees M, Gardiner RM (2004). Childhood absence epilepsy: identification of sequence variants, linkage disequilibrium and allelic association in CACNG3.  Author URL.
Everett KV, Chioza BA, Robinson R, Taske N, Rees M, Gardiner RM (2004). Childhood absence epilepsy: two-locus linkage analysis of CACNG3 on chromosome 16p and the GABAA receptor gene cluster on chromosome 15q11-13.  Author URL.
Nashef L, Osei-Lah A, Chioza B, Wilkie H, Asherson P, Makoff A (2003). Genetic association study of idiopathic generalised epilepsy.  Author URL.
Makoff AJ, Asherson P, Chioza B, Wilkie H, Nashef L (2002). Identification of genes predisposing to idiopathic generalised epilepsy.  Author URL.
Chioza BA, Goodwin HJ, McCormick D, Blower J, Nashef L, Asherson P, Makoff AJ (2000). An association study of the calcium channel gene CACNA1A and idiopathic generalised epilepsy.  Author URL.
Goodwin HJ, Chioza BA, McCormick D, Nashef L, Asherson P, Makoff AJ (2000). Positive association found between the α7 nicotinic acetylcholine receptor subunit gene and idiopathic generalised epilepsy.  Author URL.
Goodwin HJ, Chioza BA, Riley B, McCormick D, Nashef L, Asherson P, Makoff AJ (1999). An association study of the a7 nicotinic acetylcholine receptor subunit and idiopathic generalised epilepsy.  Author URL.
Al-Chalabi A, Andersen P, Chioza B, Shaw C, Roberecht W, Camu W, Leigh PN, Powell J (1998). The D90A SOD1 mutation in amyotrophic lateral sclerosis in Scandinavia: Evidence for a founder effect.  Author URL.

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