TRD Decision Algorithm

Exeter Consensus Statement for Treatment Resistant Depression

Treatment Resistant Depression

The Exeter Consensus Statement


'Patients with a diagnosis of major depressive disorder who remain clinically depressed after two or more different evidence-based treatments, which must include two different classes of antidepressants, where all treatments have been delivered at an adequate dose, adhered to by the patient for the recommended duration for that treatment, and where non response is unrelated to substance abuse.’


Professor David Richards presented The Exeter Consensus Statement at the University of Sheffield on 12th November 2013, hosted by CLAHRC South Yorkshire's Mental Health Theme: Improving Quality and Effectiveness of Services Therapies and Self-management in longer-term depression (iQuESTS).

The slides from the event are available to download here: Exeter Consensus Statement.