Exeter IBD and Pharmacogenetics Research Group

The Exeter IBD and Pharmacogenetics Research group is headed up by Dr Tariq Ahmad, Consultant Gastroenterologist at the Royal Devon and Exeter Hospital. It was formed in March 2011 to initially investigate the genetics around side effects caused by taking drugs used in Inflammatory Bowel Disease (IBD). The aims of the group are to raise the profile of IBD, to increase research in this field and to help to improve the health outcomes and management of patients with Crohn’s disease and ulcerative colitis.

The group has built a large infrastructure across the UK and has many international collaborators in which it can conduct its research. The current projects included six studies, predicting serious drug side effects in gastroenterology (PRED4) which are retrospective studies to further investigate drug side effects and a prospective observation study, looking to personalised anti-TNF therapy in Crohn’s disease (PANTS).

The studies are supported by the National Institute for Health Research (NIHR) and the group receives funding and grant support from the international serious adverse event consortium (I SAE), IBD charities and pharmaceutical companies.

Research studies

CLARITY IBD - Impact of Biologic and Immunomodulatory Therapy on SARS-CoV-2 Infection and Immunity in Patients with Inflammatory Bowel Disease

PANTS - Personalised Anti-TNF Therapy in Crohn's disease

PRED4 - Predicting Serious Drug Side Effects in Gastroenterology

Meet the team

	Tariq Ahmed	Honorary Senior Clinical Lecturer, University of Exeter Medical School Consultant Gastroenterologist, Royal Devon University Healthcare NHS Foundation trust
	Nick Kennedy	Honorary Senior Clinical Lecturer, University of Exeter Medical School Consultant Gastroenterologist, Royal Devon University Healthcare NHS Foundation trust
	James Goodhand	Honorary Senior Clinical Lecturer, University of Exeter Medical School Consultant Gastroenterologist, Royal Devon University Healthcare NHS Foundation trust
	Claire Bewshea	Project Manager
	Neil Chanchlani	IBD Research Fellow Paediatric Specialist Registrar
	Simeng Lin	PhD student, IBD Research Fellow Gastroenterology Specialist Registrar
	Rachel Nice	PhD Student Senior Biomedical Scientist
	Rebecca Smith	IBD Research Fellow Gastroenterology Specialist Registrar
	Chris Roberts	Academic Clinical Fellow in Gastroenterology Internal Medicine Trainee
	Marian Parkinson	Project Co-ordinator
	Helen Gardener-Thorpe	Project Administrator
	Alumni	Benjamin Hamilton Malik Janjua Desmond Chee Claire Gordan Amanda Thomas Gareth Walker Neel Heerasing Peter Hendy Graham Heap Abhey Singh