COLLEGE OF MEDICINE AND HEALTH
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Neil Chanchlani

 01392 406813

 RILD Building IBD Pharmacogenetics,3rd floor

 

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Overview

Neil is a clinical research fellow working with Prof. Tariq Ahmad and Prof. Mike Weedon in the Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group. His PhD focuses on mechanisms of anti-TNF treatment failure in adults and children with inflammatory bowel disease. He is also a paediatric doctor in training with an interest in gastroenterology, hepatology, and nutrition, and Associate Editor, CMAJ.

Qualifications

2009 - BA (Hons) Biomedical and Healthcare Ethics, University of Leeds
2013 - MBChB Medicine, University of Birmingham
2017 - MRCPCH, Royal College of Paediatrics and Child Health
2020 - MSc Epidemiology, London School of Hygiene and Tropical Medicine

Links

Research

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Chanchlani N, Rack D, Hossain U, Leigh A (2021). 14-month old boy with abrupt-onset petechiae and bruising. Arch Dis Child Educ Pract Ed, 106(1), 35-37. Author URL.
Kennedy NA, Goodhand JR, Bewshea C, Nice R, Chee D, Lin S, Chanchlani N, Butterworth J, Cooney R, Croft NM, et al (2021). Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab. Gut, 70(5), 865-875. Abstract.
Kennedy NA, Lin S, Goodhand JR, Chanchlani N, Hamilton B, Bewshea C, Nice R, Chee D, Cummings JF, Fraser A, et al (2021). Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD. Gut, 70(10), 1884-1893. Abstract.  Author URL.
Chanchlani N, Parke SC, Hart JW (2021). Langerhans cell histiocytosis in a 5-month-old baby. CMAJ, 193(1). Author URL.
Nice R, Chanchlani N, Green H, Bewshea C, Ahmad T, Goodhand JR, McDonald TJ, Perry MH, Kennedy NA (2021). Validating the positivity thresholds of drug-tolerant anti-infliximab and anti-adalimumab antibody assays. Aliment Pharmacol Ther, 53(1), 128-137. Abstract.  Author URL.
Chanchlani N, Buchanan F, Gill PJ (2020). Addressing the indirect effects of COVID-19 on the health of children and young people. CMAJ, 192(32), E921-E927. Author URL.
Chanchlani N, Jarvis P, Hart JW, McMillan CH, Moudiotis CR (2020). Adolescent with abdominal pain poorly responsive to analgesia. Archives of disease in childhood - Education & practice edition Abstract.
Lin S, Green HD, Hendy P, Heerasing NM, Chanchlani N, Hamilton B, Walker GJ, Heap GA, Hobart J, Martin RJ, et al (2020). Clinical features and genetic risk of demyelination following anti-TNF treatment. J Crohns Colitis Abstract.  Author URL.  Full text.
Levine A, Chanchlani N, Hussey S, Ziv-Baran T, Escher JC, Amil Dias J, Veres G, Koletzko S, Turner D, Kolho K-L, et al (2020). Complicated Disease and Response to Initial Therapy Predicts Early Surgery in Paediatric Crohn's Disease: Results from the Porto Group GROWTH Study. J Crohns Colitis, 14(1), 71-78. Abstract.  Author URL.
Chanchlani N, Hodes D (2020). Fifteen-minute consultation: Vulval soreness in the prepubertal girl. Arch Dis Child Educ Pract Ed Author URL.
Sazonovs A, Kennedy NA, Moutsianas L, Heap GA, Rice DL, Reppell M, Bewshea CM, Chanchlani N, Walker GJ, Perry MH, et al (2020). HLA-DQA1*05 Carriage Associated with Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients with Crohn's Disease. Gastroenterology, 158(1), 189-199. Abstract.  Author URL.
Hamilton B, Green H, Heerasing N, Hendy P, Moore L, Chanchlani N, Walker G, Bewshea C, Kennedy NA, Ahmad T, et al (2020). Incidence and prevalence of inflammatory bowel disease in Devon, UK. Frontline Gastroenterology Abstract.
Chanchlani N, Walters TD, Russell RK (2020). Managing nonspecific abdominal pain in children and young people. Canadian Medical Association Journal, 192(48), E1639-E1640.
Walker GJ, Chanchlani N, Thomas A, Lin S, Moore L, Heerasing NM, Hendy P, Abdelrahim M, Mole S, Perry MH, et al (2020). Primary care faecal calprotectin testing in children with suspected inflammatory bowel disease: a diagnostic accuracy study. Arch Dis Child, 105(10), 957-963. Abstract.  Author URL.
Walker GJ, Lin S, Chanchlani N, Thomas A, Hendy P, Heerasing N, Moore L, Green HD, Chee D, Bewshea C, et al (2020). Quality improvement project identifies factors associated with delay in IBD diagnosis. Alimentary Pharmacology & Therapeutics, 52(3), 471-480.
Honap S, Chee D, Chapman TP, Patel M, Kent AJ, Ray S, Sharma E, Kennedy J, Cripps S, Walsh A, et al (2020). Real-world Effectiveness of Tofacitinib for Moderate to Severe Ulcerative Colitis: a Multicentre UK Experience. J Crohns Colitis, 14(10), 1385-1393. Abstract.  Author URL.
Gordon C, Chee D, Hamilton B, Chanchlani N, Heerasing NM, Hendy P, Lin S, Wesley E, Daniels I, Goodhand JR, et al (2020). Root cause analysis to identify missed opportunities for the diagnosis of colorectal cancer in inflammatory bowel disease. JOURNAL OF CROHNS & COLITIS, 14, S273-S275. Author URL.
Chanchlani N, Reading NG (2019). A middle aged man with back pain and heavy legs. BMJ, 366 Author URL.
Christie D, Chanchlani N, Salehian S (2019). Fever and tachypnoea in a child. BMJ (Online), 365
Chanchlani N, Russell RK (2019). Inflammatory bowel disease in children and adolescents. CMAJ, 191(6). Author URL.
Bewshea CM, Ahmad T, Kennedy N, Goodhand J, McDonald T, Green H (2019). Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study. Lancet Gastroenterology and Hepatology Full text.
Kapeller K, Chanchlani N (2019). Tips for the childhood immunisation OSCE. BMJ, 364 Author URL.
Chanchlani N, Mortier K, Williams LJ, Muhammed R, Auth MKH, Cosgrove M, Fagbemi A, Fell J, Chong S, Zamvar V, et al (2018). Use of Infliximab Biosimilar Versus Originator in a Pediatric United Kingdom Inflammatory Bowel Disease Induction Cohort. J Pediatr Gastroenterol Nutr, 67(4), 513-519. Abstract.  Author URL.
Dhanjal S, Green M, Pearce J, Chanchlani N (2017). Better information sharing and reinforcement of facts needed during transition of young people with epilepsy. Epilepsy Behav, 73, 283-284. Author URL.
Chanchlani N, Reading NG, Goodhand JR (2017). Haemosuccus pancreaticus. BMJ (Online), 356
Chanchlani N, Davis F, Devarajan K (2017). Ongoing vomiting in an infant. BMJ, 357 Author URL.
Wong ML, Chanchlani N, Croft G (2017). Out of place: recognising, understanding and responding to the health needs of looked after refugee and trafficked children and young people – conference report. Adoption and Fostering, 41(1), 91-95.
Wolfe I, Sigfrid L, Chanchlani N, Lenton S (2016). Child Health Systems in the United Kingdom (England). J Pediatr, 177S, S217-S242. Abstract.  Author URL.
Chanchlani N, Harewood C, Hossain U, Leigh A (2015). Better Transition Readiness for Adolescents Begins with Effective Communication. J Pediatr Hematol Oncol, 37(7), 574-575. Author URL.
Chanchlani N, McGee M, McDonagh JE (2015). Informational continuity is integral for successful transition of adolescents to adult care. J Rheumatol, 42(5), 901-902. Author URL.
Sandoo A, Chanchlani N, Hodson J, Smith JP, Douglas KM, Kitas GD (2014). The relationship between cardiovascular disease risk prediction scores and vascular function and morphology in rheumatoid arthritis. Clin Exp Rheumatol, 32(6), 914-921. Abstract.  Author URL.
Sandoo A, Chanchlani N, Hodson J, Smith JP, Douglas KM, Kitas GD (2013). Classical cardiovascular disease risk factors associate with vascular function and morphology in rheumatoid arthritis: a six-year prospective study. Arthritis Res Ther, 15(6). Abstract.  Author URL.
Chanchlani N, Neale E, Rylance PB (2012). A South African man with renal failure and pulmonary shadowing. BMJ, 344 Author URL.
Chanchlani N, Godlee F (2012). Educating tomorrow's doctors. BMJ, 344 Author URL.

Publications by year


2021

Chanchlani N, Rack D, Hossain U, Leigh A (2021). 14-month old boy with abrupt-onset petechiae and bruising. Arch Dis Child Educ Pract Ed, 106(1), 35-37. Author URL.
Kennedy NA, Goodhand JR, Bewshea C, Nice R, Chee D, Lin S, Chanchlani N, Butterworth J, Cooney R, Croft NM, et al (2021). Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab. Gut, 70(5), 865-875. Abstract.
Kennedy NA, Lin S, Goodhand JR, Chanchlani N, Hamilton B, Bewshea C, Nice R, Chee D, Cummings JF, Fraser A, et al (2021). Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD. Gut, 70(10), 1884-1893. Abstract.  Author URL.
Chanchlani N, Parke SC, Hart JW (2021). Langerhans cell histiocytosis in a 5-month-old baby. CMAJ, 193(1). Author URL.
Nice R, Chanchlani N, Green H, Bewshea C, Ahmad T, Goodhand JR, McDonald TJ, Perry MH, Kennedy NA (2021). Validating the positivity thresholds of drug-tolerant anti-infliximab and anti-adalimumab antibody assays. Aliment Pharmacol Ther, 53(1), 128-137. Abstract.  Author URL.

2020

Chanchlani N, Buchanan F, Gill PJ (2020). Addressing the indirect effects of COVID-19 on the health of children and young people. CMAJ, 192(32), E921-E927. Author URL.
Chanchlani N, Jarvis P, Hart JW, McMillan CH, Moudiotis CR (2020). Adolescent with abdominal pain poorly responsive to analgesia. Archives of disease in childhood - Education & practice edition Abstract.
Lin S, Green HD, Hendy P, Heerasing NM, Chanchlani N, Hamilton B, Walker GJ, Heap GA, Hobart J, Martin RJ, et al (2020). Clinical features and genetic risk of demyelination following anti-TNF treatment. J Crohns Colitis Abstract.  Author URL.  Full text.
Levine A, Chanchlani N, Hussey S, Ziv-Baran T, Escher JC, Amil Dias J, Veres G, Koletzko S, Turner D, Kolho K-L, et al (2020). Complicated Disease and Response to Initial Therapy Predicts Early Surgery in Paediatric Crohn's Disease: Results from the Porto Group GROWTH Study. J Crohns Colitis, 14(1), 71-78. Abstract.  Author URL.
Chanchlani N, Hodes D (2020). Fifteen-minute consultation: Vulval soreness in the prepubertal girl. Arch Dis Child Educ Pract Ed Author URL.
Sazonovs A, Kennedy NA, Moutsianas L, Heap GA, Rice DL, Reppell M, Bewshea CM, Chanchlani N, Walker GJ, Perry MH, et al (2020). HLA-DQA1*05 Carriage Associated with Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients with Crohn's Disease. Gastroenterology, 158(1), 189-199. Abstract.  Author URL.
Hamilton B, Green H, Heerasing N, Hendy P, Moore L, Chanchlani N, Walker G, Bewshea C, Kennedy NA, Ahmad T, et al (2020). Incidence and prevalence of inflammatory bowel disease in Devon, UK. Frontline Gastroenterology Abstract.
Chanchlani N, Walters TD, Russell RK (2020). Managing nonspecific abdominal pain in children and young people. Canadian Medical Association Journal, 192(48), E1639-E1640.
Walker GJ, Chanchlani N, Thomas A, Lin S, Moore L, Heerasing NM, Hendy P, Abdelrahim M, Mole S, Perry MH, et al (2020). Primary care faecal calprotectin testing in children with suspected inflammatory bowel disease: a diagnostic accuracy study. Arch Dis Child, 105(10), 957-963. Abstract.  Author URL.
Walker GJ, Lin S, Chanchlani N, Thomas A, Hendy P, Heerasing N, Moore L, Green HD, Chee D, Bewshea C, et al (2020). Quality improvement project identifies factors associated with delay in IBD diagnosis. Alimentary Pharmacology & Therapeutics, 52(3), 471-480.
Honap S, Chee D, Chapman TP, Patel M, Kent AJ, Ray S, Sharma E, Kennedy J, Cripps S, Walsh A, et al (2020). Real-world Effectiveness of Tofacitinib for Moderate to Severe Ulcerative Colitis: a Multicentre UK Experience. J Crohns Colitis, 14(10), 1385-1393. Abstract.  Author URL.
Gordon C, Chee D, Hamilton B, Chanchlani N, Heerasing NM, Hendy P, Lin S, Wesley E, Daniels I, Goodhand JR, et al (2020). Root cause analysis to identify missed opportunities for the diagnosis of colorectal cancer in inflammatory bowel disease. JOURNAL OF CROHNS & COLITIS, 14, S273-S275. Author URL.

2019

Chanchlani N, Reading NG (2019). A middle aged man with back pain and heavy legs. BMJ, 366 Author URL.
Christie D, Chanchlani N, Salehian S (2019). Fever and tachypnoea in a child. BMJ (Online), 365
Chanchlani N, Russell RK (2019). Inflammatory bowel disease in children and adolescents. CMAJ, 191(6). Author URL.
Bewshea CM, Ahmad T, Kennedy N, Goodhand J, McDonald T, Green H (2019). Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study. Lancet Gastroenterology and Hepatology Full text.
Kapeller K, Chanchlani N (2019). Tips for the childhood immunisation OSCE. BMJ, 364 Author URL.

2018

Chanchlani N, Mortier K, Williams LJ, Muhammed R, Auth MKH, Cosgrove M, Fagbemi A, Fell J, Chong S, Zamvar V, et al (2018). Use of Infliximab Biosimilar Versus Originator in a Pediatric United Kingdom Inflammatory Bowel Disease Induction Cohort. J Pediatr Gastroenterol Nutr, 67(4), 513-519. Abstract.  Author URL.

2017

Dhanjal S, Green M, Pearce J, Chanchlani N (2017). Better information sharing and reinforcement of facts needed during transition of young people with epilepsy. Epilepsy Behav, 73, 283-284. Author URL.
Chanchlani N, Reading NG, Goodhand JR (2017). Haemosuccus pancreaticus. BMJ (Online), 356
Chanchlani N, Davis F, Devarajan K (2017). Ongoing vomiting in an infant. BMJ, 357 Author URL.
Wong ML, Chanchlani N, Croft G (2017). Out of place: recognising, understanding and responding to the health needs of looked after refugee and trafficked children and young people – conference report. Adoption and Fostering, 41(1), 91-95.

2016

Wolfe I, Sigfrid L, Chanchlani N, Lenton S (2016). Child Health Systems in the United Kingdom (England). J Pediatr, 177S, S217-S242. Abstract.  Author URL.

2015

Chanchlani N, Harewood C, Hossain U, Leigh A (2015). Better Transition Readiness for Adolescents Begins with Effective Communication. J Pediatr Hematol Oncol, 37(7), 574-575. Author URL.
Chanchlani N, McGee M, McDonagh JE (2015). Informational continuity is integral for successful transition of adolescents to adult care. J Rheumatol, 42(5), 901-902. Author URL.

2014

Sandoo A, Chanchlani N, Hodson J, Smith JP, Douglas KM, Kitas GD (2014). The relationship between cardiovascular disease risk prediction scores and vascular function and morphology in rheumatoid arthritis. Clin Exp Rheumatol, 32(6), 914-921. Abstract.  Author URL.

2013

Sandoo A, Chanchlani N, Hodson J, Smith JP, Douglas KM, Kitas GD (2013). Classical cardiovascular disease risk factors associate with vascular function and morphology in rheumatoid arthritis: a six-year prospective study. Arthritis Res Ther, 15(6). Abstract.  Author URL.

2012

Chanchlani N, Neale E, Rylance PB (2012). A South African man with renal failure and pulmonary shadowing. BMJ, 344 Author URL.
Chanchlani N, Godlee F (2012). Educating tomorrow's doctors. BMJ, 344 Author URL.

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