Publications by category
Journal articles
Jones ML, Barnish MS, Hughes RR, Murray AK, Mansour O, Loni T, Vickery HM, Evans ML, Green L, Verdezoto N, et al (2023). Exploring the potential of using simulation games for engaging with sheep farmers about lameness recognition.
Front Vet Sci,
10Abstract:
Exploring the potential of using simulation games for engaging with sheep farmers about lameness recognition.
INTRODUCTION: Computer simulation games are increasingly being used in agriculture as a promising tool to study, support and influence real-life farming practices. We explored the potential of using simulation games to engage with sheep farmers on the ongoing challenge of reducing lameness. Working with UK stakeholders, we developed a game in which players are challenged with identifying all the lame sheep in a simulated flock. Here, we evaluate the game's potential to act as a tool to help assess, train and understand farmers' ability to recognize the early signs of lameness. METHODS: Participants in the UK were invited to play the game in an online study, sharing with us their in-game scores alongside information relating to their real-life farming experience, how they played the game, and feedback on the game. Mixed methods were used to analyze this information in order to evaluate the game. Quantitative analyses consisted of linear modeling to test for statistical relationships between participants' in-game recall (% of the total number of lame sheep that were marked as lame), and the additional information they provided. Qualitative analyses of participants' feedback on the game consisted of thematic analysis and a Likert Scale questionnaire to contextualize the quantitative results and identify additional insights from the study. RESULTS: Quantitative analyses identified no relationships between participants' (n = 63) recall scores and their real life farming experience, or the lameness signs they looked for when playing the game. The only relationship identified was a relationship between participants' recall score and time spent playing the game. Qualitative analyses identified that participants did not find the game sufficiently realistic or engaging, though several enjoyed playing it and saw potential for future development. Qualitative analyses also identified several interesting and less-expected insights about real-life lameness recognition practices that participants shared after playing the game. DISCUSSION: Simulation games have potential as a tool in livestock husbandry education and research, but achieving the desired levels of realism and/or engagingness may be an obstacle to realizing this. Future research should explore this potential further, aided by larger budgets and closer collaboration with farmers, stockpeople, and veterinarians.
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Barnish MS, Nelson-Horne RV (2023). Group-based active artistic interventions for adults with primary anxiety and depression: a systematic review.
BMJ Open,
13(6), e069310-e069310.
Abstract:
Group-based active artistic interventions for adults with primary anxiety and depression: a systematic review
ObjectivesThis systematic review examined the potential benefit of all group-based performing arts interventions for primary anxiety and/or depression.SettingScholarly literature from any country or countries globally.Data sourcesThree key bibliographic databases, Google Scholar and relevant citation chasing.Primary and secondary outcome measuresDepression and/or anxiety symptom severity, well-being, quality of life, functional communication or social participation.ResultsDatabase searches returned a total of 63 678 records, of which 56 059 remained following dededuplication. From these database searches, a total of 153 records proceeded to full-text screening. These were supplemented by 18 additional unique full-text screening records from Google Scholar searches and citation chasing (12% of total). From a total of 171 records at the full-text screening stage, 12 publications (7%) were eligible for inclusion in this systematic review, each reporting on a separate study. Published from 2004 to 2021, these studies involved a total of 669 participants with anxiety and/or depression from nine countries and covered five broad artistic modalities: dance, music therapy, art therapy, martial arts and theatre. Dance was the most studied artistic modality (five studies), while there were three studies on art therapy, two on music therapy and one each on martial arts and theatre. The evidence was clearest for a benefit of arts therapies on depression and/or anxiety symptoms.ConclusionsThis systematic review addresses all group-based active arts interventions in a focused population of primary anxiety and/or depression. The evidence suggests that the arts may be a useful therapeutic medium in this population. However, a substantial limitation of the evidence base is the lack of studies directly comparing different artistic modalities. Moreover, not all artistic modalities were assessed for all outcome domains. Therefore, it is not currently possible to determine which artistic modalities are most beneficial for which specific outcomes.
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Barnish MS, Tan SY, Taeihagh A, Tørnes M, Nelson-Horne RVH, Melendez-Torres GJ (2021). Linking political exposures to child and maternal health outcomes: a realist review.
BMC Public Health,
21(1).
Abstract:
Linking political exposures to child and maternal health outcomes: a realist review
Background: Conceptual and theoretical links between politics and public health are longstanding. Internationally comparative systematic review evidence has shown links between four key political exposures – the welfare state, political tradition, democracy and globalisation – on population health outcomes. However, the pathways through which these influences may operate have not been systematically appraised. Therefore, focusing on child and maternal health outcomes, we present a realist re-analysis of the dataset from a recent systematic review. Methods: the database from a recent systematic review on the political determinants of health was used as the data source for this realist review. Included studies from the systematic review were re-evaluated and those relating to child and/or maternal health outcomes were included in the realist synthesis. Initial programme theories were generated through realist engagement with the prior systematic review. These programme theories were adjudicated and refined through detailed engagement with the evidence base using a realist re-synthesis involving two independent reviewers. The revised theories that best corresponded to the evidence base formed the final programme theories. Results: Out of the 176 included studies from the systematic review, a total of 67 included child and/or maternal health outcomes and were included in the realist re-analysis. Sixty-three of these studies were ecological and data were collected between 1950 and 2014. Six initial programme theories were generated. Following theory adjudication, three theories in revised form were supported and formed the final programme theories. These related to a more generous welfare state leading to better child and maternal health especially in developed countries through progressive social welfare policies, left-of-centre political tradition leading to lower child mortality and low birth weight especially in developed countries through greater focus on welfare measures, and increased globalisation leading to greater child and infant mortality and youth smoking rates in LMECs through greater influence of multinational corporations and neoliberal trade organisations. Conclusion: We present a realist re-analysis of a large systematically identified body of evidence on how four key political exposures – the welfare state, democracy, political tradition and globalisation – relate to child and maternal health outcomes. Three final programme theories were supported.
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Barnish MS, Barran SM (2020). A systematic review of active group-based dance, singing, music therapy and theatrical interventions for quality of life, functional communication, speech, motor function and cognitive status in people with Parkinson’s disease.
BMC Neurology,
20(1).
Abstract:
A systematic review of active group-based dance, singing, music therapy and theatrical interventions for quality of life, functional communication, speech, motor function and cognitive status in people with Parkinson’s disease
Abstract
. Background
. Parkinson’s disease (PD) is a common neurodegenerative condition associated with a wide range of motor and non-motor symptoms. There has been increasing interest in the potential benefit of performing arts as a therapeutic medium in PD. While there have been previous reviews, none have considered all performing arts modalities and most have focused on dance. This systematic review examined the potential benefit of all active group-based performing arts interventions for quality of life, functional communication, speech, motor function and cognitive status.
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. Methods
. Searches were conducted in February 2020 on five scholarly databases. Supplementary searches were conducted. Included studies were quantitative in design, and assessed the potential benefit of any active group-based performing arts intervention for quality of life, functional communication, speech, motor function or cognitive status in people with PD. Full text papers were eligible for inclusion, as were conference abstracts since January 2018. Screening, data extraction, narrative synthesis and quality assessment were conducted independently by two reviewers. Quality assessment used the SURE checklists.
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. Results
. Fifty-six studies were eligible for inclusion in this systematic review, reported in 67 publications. Published from 1989 to 2020, these studies included a total of 1531 people with PD from 12 countries, and covered four broad performing arts modalities: dance, singing, music therapy and theatre. Dance remains the most commonly studied performing arts modality for PD (38 studies), while there were 12 studies on singing interventions, four on music therapy, and only two on theatrical interventions. There was evidence for a beneficial effect of all four performing arts modalities on at least some outcome domains.
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. Conclusions
. This is the first systematic review to assess the potential benefit of all active group-based performing arts interventions in PD. The evidence suggests that performing arts may be a useful therapeutic medium in PD. However, a substantial limitation of the evidence base is that no studies compared interventions from different performing arts modalities. Moreover, not all performing arts modalities were assessed for all outcome domains. Therefore it is not currently possible to determine which performing arts modalities are most beneficial for which specific outcomes.
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Barnish M, Daley DJ, Deane KHO, Clark AB, Gray RJ, Horton SMC, Butterfint ZR, Myint PK (2019). Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease. Medical Journal of the Islamic Republic of Iran, 33
Barnish M, Daley DJ, Deane KHO, Clark AB, Gray RJ, Horton SMC, Butterfint ZR, Myint PK (2019). Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease.
Medical Journal of the Islamic Republic of Iran,
33(1), 1-5.
Abstract:
Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease
Background: the Montreal Cognitive Assessment (MoCA) has been recommended as a cognitive screening tool for clinical practice and research in Parkinson's disease (PD), yet no normative data have been published for MoCA in PD without dementia. Methods: We undertook a pooled secondary analysis of data from two studies (one cross-sectional design and one clinical trial) conducted in the East of England region. All participants were aged 18 years or over, met UK Brain Bank criteria for PD and did not have clinical dementia. Cognitive status was assessed using MoCA at baseline in both studies. The influences of age, gender, disease duration, medication load (LEDD) and mood (HADS) on cognition were examined using regression analysis. Results: Data from 101 people with PD without dementia were available (mean age 71 years, 66% men). Median (IQR) MoCA was 25(22, 27). Age was found as the only predictor of MoCA in this sample. People aged over 71 had poorer MoCA (Beta=0.6 (95%CI 0.44, 0.82)) and an increased odds of MoCA < 26 (Beta=0.29 (95%CI 0.12, 0.70)) as well as poorer scores on several MoCA sub-domains. Conclusion: We present the normative data for MoCA in people with PD without clinical dementia. Age appeared to be the only associated factor for lower level of cognition, suggestive of Mild cognitive impairment in PD (PD-MCI) in PD without clinical diagnosis of dementia.
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Barnish M, Daley DJ, Deane KH, Clark AB, Gray RJ, Horton SM, Butterfint ZR, Myint PK (2019). Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease.
Med J Islam Repub Iran,
33Abstract:
Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease.
Background: the Montreal Cognitive Assessment (MoCA) has been recommended as a cognitive screening tool for clinical practice and research in Parkinson's disease (PD), yet no normative data have been published for MoCA in PD without dementia. Methods: We undertook a pooled secondary analysis of data from two studies (one cross-sectional design and one clinical trial) conducted in the East of England region. All participants were aged 18 years or over, met UK Brain Bank criteria for PD and did not have clinical dementia. Cognitive status was assessed using MoCA at baseline in both studies. The influences of age, gender, disease duration, medication load (LEDD) and mood (HADS) on cognition were examined using regression analysis. Results: Data from 101 people with PD without dementia were available (mean age 71 years, 66% men). Median (IQR) MoCA was 25(22, 27). Age was found as the only predictor of MoCA in this sample. People aged over 71 had poorer MoCA (Beta=0.6 (95%CI 0.44, 0.82)) and an increased odds of MoCA
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Whibley D, AlKandari N, Kristensen K, Barnish M, Rzewuska M, Druce KL, Tang NKY (2019). Sleep and Pain: a Systematic Review of Studies of Mediation.
Clin J Pain,
35(6), 544-558.
Abstract:
Sleep and Pain: a Systematic Review of Studies of Mediation.
OBJECTIVES: a relationship between sleep and pain is well established. A better understanding of the mechanisms that link sleep and pain intensity is urgently needed to optimize pain management interventions. The objective of this systematic review was to identify, synthesize, and critically appraise studies that have investigated putative mediators on the path between sleep and pain intensity. METHODS: a systematic search of 5 electronic bibliographic databases (EMBASE, MEDLINE, CINAHL, PsycINFO, and the Cochrane Central Register of Controlled Trials) was conducted. Eligible studies had to apply a formal test of mediation to variables on the path between a sleep variable and pain intensity or vice versa. All searches, data extraction and quality assessment were conducted by at least 2 independent reviewers. RESULTS: the search yielded 2839 unique articles, 9 of which were eligible. of 13 mediation analyses, 11 investigated pathways from a sleep variable to pain intensity. Putative mediators included affect/mood, depression and/or anxiety, attention to pain, pain helplessness, stress, fatigue, and physical activity. Two analyses investigated pathways from pain intensity to a sleep variable, examining the potentially mediating role of depressive symptoms and mood. Although evidence supported a mediating role for psychological and physiological aspects of emotional experiences and attentional processes, methodological limitations were common, including use of cross-sectional data and minimal adjustment for potential confounders. DISCUSSION: a growing body of research is applying mediation analysis to elucidate mechanistic pathways between sleep and pain intensity. Currently sparse evidence would be illuminated by more intensively collected longitudinal data and improvements in analysis.
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Varley-Campbell J, Mujica Mota R, Coelho H, Ocean N, Barnish M, Packman D, Dodman S, Cooper C, Snowsill TM, Kay T, et al (2019). Three biomarker tests to help diagnose preterm labour: a systematic review and economic evaluation. Health Technology Assessment, 23(13).
Barnish M, Tørnes M, Nelson-Horne B (2018). How much evidence is there that political factors are related to population health outcomes? an internationally comparative systematic review. BMJ Open, 8, e020886-e020886.
Varley-Campbell J, Cooper C, Coelho H, Dodman S, Barnish M, Mujica-Mota R, Hyde C, Hoyle M (2018). OP136 Full Texts Versus Conference Abstract Data: How Does the Message Change?. International Journal of Technology Assessment in Health Care, 34(S1), 50-51.
Barnish M (2018). The inclusion of retracted studies in systematic reviews: a response to Gray et al. (2018). International Journal of Nursing Studies, 80, 90-91.
Barnish MS, Tagiyeva N, Devereux G, Aucott L, Turner S (2017). Changes in the relationship between asthma and associated risk factors over fifty years.
Pediatric Allergy and Immunology,
28(2), 162-169.
Abstract:
Changes in the relationship between asthma and associated risk factors over fifty years
Background: Childhood asthma is a common condition whose prevalence is changing. We hypothesized that the relationship between asthma and associated risk factors has changed over a 50-year period. Methods: an ecological study design was used. Children aged 8–13 attending schools in Aberdeen city were surveyed on seven occasions between 1964 and 2014. The following were determined: history of asthma, history of eczema, parental smoking, parental asthma, sex and socio-economic status. Analysis was by a structural change model with two knots. The outcome reported was the change in odds ratio between asthma and a given risk factor during a given period. Results: There were 23,241 questionnaires distributed and 17,439 returned (75%). The odds ratio (OR) for a child with asthma to have eczema increased between 1989 and 1999 by 1.031 [95% CI 1.028, 1.035] and by 1.042 between 2004 and 2014 [1.038, 1.047]. The OR for a child with asthma to have a parent who smoked rose by 1.032 [1.028, 1.036] between 1989 and 1999 and by 1.043 [1.038, 1.047] between 2004 and 2014), and to have a parent with asthma (1.027 [1.022, 1.031] for 1994–99 and 1.042 [1.037, 1.048] for 2004–2014). The OR for a child with asthma being male, but not and being from the most deprived communities, rose between 1989–1999 and 2004–2014. Conclusions: the relationship between asthma prevalence and particular risk factors changed over the 50-year period of study, and this might reflect changes in children's environment and/or susceptibility.
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Macfarlane GJ, Barnish MS, Pathan E, Martin KR, Haywood KL, Siebert S, Packham J, Atzeni F, Jones GT (2017). Co‐Occurrence and Characteristics of Patients with Axial Spondyloarthritis Who Meet Criteria for Fibromyalgia.
Arthritis & Rheumatology,
69(11), 2144-2150.
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Co‐Occurrence and Characteristics of Patients with Axial Spondyloarthritis Who Meet Criteria for Fibromyalgia
ObjectiveTo estimate the proportion of patients with axial spondyloarthritis (SpA) in a UK national biologics registry who met criteria for fibromyalgia (FM), and to delineate the characteristics of these patients.MethodsTwo cohorts of patients are prospectively recruited from across 83 centers in the UK for the British Society for Rheumatology Biologics Register in Ankylosing Spondylitis (BSRBR‐AS). All patients are required to meet Assessment of SpondyloArthritis international Society (ASAS) criteria for axial SpA. Patients are either newly starting biologic therapy (biologics cohort) or are naive to treatment with biologic agents (non‐biologics cohort) at the time of recruitment, and all patients are followed up prospectively. At recruitment and follow‐up, clinical information and measurements are recorded while patients complete the 2011 research criteria for FM and assessments of the level of disease activity and work impact.ResultsOf the patients registered in the BSRBR‐AS, 1,504 (68% male) were eligible for the current analysis, of whom 311 (20.7%) met the 2011 research criteria for FM. Prevalence of FM was similar between patients who fulfilled the modified New York criteria for AS (19.7%) and those who fulfilled ASAS imaging criteria but not the modified New York criteria (25.2%); however, among those who fulfilled only the ASAS clinical criteria, the prevalence of FM was lower (9.5%). Patients who met FM criteria reported significantly worse disease activity, function, global severity scores, and quality of life, and were more likely to have moderate or severe levels of mood disorder and clinically important fatigue. Patients who met FM criteria reported experiencing work impairment around half their working time. Meeting FM criteria was not related to elevated C‐reactive protein levels or most extraspinal manifestations, but was associated with a higher likelihood of having received biologic therapy.ConclusionDeveloping management approaches that would address the significant unmet clinical needs of the 1 in 5 patients with axial SpA who meet criteria for FM should be a research priority.
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Macfarlane GJ, Barnish MS, Jones GT (2017). Persons with chronic widespread pain experience excess mortality: longitudinal results from UK Biobank and meta-analysis.
Ann Rheum Dis,
76(11), 1815-1822.
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Persons with chronic widespread pain experience excess mortality: longitudinal results from UK Biobank and meta-analysis.
OBJECTIVE: it is uncertain whether persons with chronic widespread pain (CWP) experience premature mortality. Using the largest study conducted, we determine whether such a relationship exists, estimate its magnitude and establish what factors mediate any relationship. METHODS: UK Biobank, a cohort study of 0.5 million people aged 40-69 years, recruited throughout Great Britain in 2006-2010. Participants reporting 'pain all over the body' for >3 months were compared with persons without chronic pain. Information on death (with cause) was available until mid-2015. We incorporated these results in a meta-analysis with other published reports to calculate a pooled estimate of excess risk. RESULTS: 7130 participants reported CWP and they experienced excess mortality (mortality risk ratio 2.43, 95%CI 2.17 to 2.72). Specific causes of death in excess were cancer (1.73adjusted age and sex, 95% CI 1.46 to 2.05), cardiovascular (3.24adjusted age and sex, 95% CI 2.55 to 4.11), respiratory (5.66adjusted age and sex, 95% CI 4.00 to 8.03) and other disease-related causes (4.04adjusted age and sex, 95% CI 3.05 to 5.34). Excess risk was substantially reduced after adjustment for low levels of physical activity, high body mass index, poor quality diet and smoking. In meta-analysis, all studies showed significant excess all-cause (combined estimate 1.59 (95% CI 1.05 to 2.42)), cardiovascular and cancer mortality. CONCLUSIONS: Evidence is now clear that persons with CWP experience excess mortality. UK Biobank results considerably reduce uncertainty around the magnitude of excess risk and are consistent with the excess being explained by adverse lifestyle factors, which could be targeted in the management of such patients.
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Barnish MS, Horton SMC, Butterfint ZR, Clark AB, Atkinson RA, Deane KHO (2017). Speech and communication in Parkinson’s disease: a cross-sectional exploratory study in the UK. BMJ Open, 7(5), e014642-e014642.
Barnish M, Morgan HM, Barnish J (2017). The 2016 HIGh Heels: Health effects and psychosexual BenefITS (HIGH HABITS) study: systematic review of reviews and additional primary studies. BMC Public Health, 18(1).
Reynolds SE, Richardson SV, Barnish M, Reid I, Ross R, Campbell R, Horne B (2017). The Politics of Women’s Fashion in the Cultural West: a Perspective. Art and Design Review, 5, 252-257.
Barnish MS, Turner S (2017). The value of pragmatic and observational studies in health care and public health.
Pragmat Obs Res,
8, 49-55.
Abstract:
The value of pragmatic and observational studies in health care and public health.
Evidence-based practice is an important component of health care service delivery. However, there is a tendency, embodied in tools such as Grades of Recommendation, Assessment, Development, and Evaluation, to focus principally on the classification of study design, at the expense of a detailed assessment of the strengths and limitations of the individual study. Randomized controlled trials (RCTs), and in particular the classical "explanatory" RCT, have a privileged place in the hierarchy of evidence. However, classical RCTs have substantial limitations, most notably a lack of generalizability, which limit their direct applicability to clinical practice implementation. Pragmatic and observational studies can provide an invaluable perspective into real-world applicability. This evidence could be used more widely to complement ideal-condition results from classical RCTs, following the principle of triangulation. In this review article, we discuss several types of pragmatic and observational studies that could be used in this capacity. We discuss their particular strengths and how their limitations may be overcome and provide real-life examples by means of illustration.
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Barnish MS, Barnish J (2016). High-heeled shoes and musculoskeletal injuries: a narrative systematic review.
BMJ Open,
6(1).
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High-heeled shoes and musculoskeletal injuries: a narrative systematic review.
OBJECTIVES: to conduct the first systematic review from an epidemiological perspective regarding the association between high-heeled shoe wear and hallux valgus, musculoskeletal pain, osteoarthritis (OA) and both first-party and second-party injury in human participants without prior musculoskeletal conditions. SETTING: a systematic review of international peer-reviewed scientific literature across seven major languages. DATA SOURCES: Searches were conducted on seven major bibliographic databases in July 2015 to initially identify all scholarly articles on high-heeled shoes. Supplementary manual searches were conducted. Titles, abstracts and full-text articles were sequentially screened to identify all articles assessing epidemiological evidence regarding the association between high-heeled shoe wear and hallux valgus, musculoskeletal pain, OA and both first-party and second-party injury in human participants without prior musculoskeletal conditions. Standardised data extraction and quality assessment (Threats to Validity tool) were conducted. PRIMARY AND SECONDARY OUTCOME MEASURES: Musculoskeletal pain or OA as assessed by clinical diagnosis or clinical assessment tool. First-party or second-party injury. RESULTS: 644 unique records were identified, 56 full-text articles were screened and 18 studies included in the review. Four studies assessed the relationship with hallux valgus and three found a significant association. Two studies assessed the association with OA and neither found a significant association. Five studies assessed the association with musculoskeletal pain and three found a significant association. Eight studies assessed first-party injury and seven found evidence of a significant injury toll associated with high-heeled shoes. One study provided data on second-party injury and the injury toll was low. CONCLUSIONS: High-heeled shoes were shown to be associated with hallux valgus, musculoskeletal pain and first-party injury. No conclusive evidence regarding OA and second-party injury was found. Societal and clinical relevance of these findings is discussed. Concern is expressed about the expectation to wear high-heeled shoes in some work and social situations and access by children.
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Barnish J, Atkinson RA, Barran SM, Barnish MS (2016). Potential Benefit of Singing for People with Parkinson's Disease: a Systematic Review.
JOURNAL OF PARKINSONS DISEASE,
6(3), 473-484.
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Barnish MS, Whibley D, Horton SMC, Butterfint ZR, Deane KHO (2016). Roles of Cognitive Status and Intelligibility in Everyday Communication in People with Parkinson's Disease: a Systematic Review.
JOURNAL OF PARKINSONS DISEASE,
6(3), 453-462.
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Barnish MS, Tagiyeva N, Devereux G, Aucott L, Turner S (2015). Diverging prevalences and different risk factors for childhood asthma and eczema: a cross-sectional study.
BMJ Open,
5(6).
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Diverging prevalences and different risk factors for childhood asthma and eczema: a cross-sectional study.
OBJECTIVE: to compare the prevalences of and risk factors for asthma, wheeze, hay fever and eczema in primary schoolchildren in Aberdeen in 2014. DESIGN: Cross-sectional survey. SETTING: Primary schools in Aberdeen, North-East Scotland. PARTICIPANTS: Children in Scottish school years primary 1-7 were handed a questionnaire by their class teacher to be completed by their parents and returned to the researchers by post or online. MAIN OUTCOME MEASURES: Lifetime history of asthma, eczema and hay fever, and recent history of wheeze. RESULTS: 41 schools agreed to participate (87%). 11,249 questionnaires were distributed and 3935 returned (35%). A parent-reported lifetime history of asthma, eczema and hay fever was present in 14%, 30% and 24% of children, respectively. The odds of lifetime asthma increased with age (OR 1.1 per year, 95% CI 1.1 to 1.2), male sex (OR 1.89, 95% CI 1.4 to 2.3), parental smoking (OR 1.7, 95% CI 1.2 to 2.3) and eczema (OR 6.6, 95% CI 5.2 to 8.4). Prevalence of recent wheeze was also reported to be 14% and was positively associated with male sex, parental smoking and eczema. In contrast, parental eczema was the only identified predictor of childhood eczema risk. CONCLUSIONS: the lifetime prevalence of asthma in primary schoolchildren was 14% in this survey, approximately half the prevalence of eczema. We report diverging prevalences in relation to previous studies in our locality, and different risk factors for asthma and eczema. These findings suggest that asthma and eczema are unlikely to have a common origin.
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Macfarlane GJ, Barnish MS, Jones EA, Kay L, Keat A, Meldrum KT, Pathan E, Sturrock RD, Zabke C, McNamee P, et al (2015). The British Society for Rheumatology Biologics Registers in Ankylosing Spondylitis (BSRBR-AS) study: Protocol for a prospective cohort study of the long-term safety and quality of life outcomes of biologic treatment.
BMC Musculoskelet Disord,
16Abstract:
The British Society for Rheumatology Biologics Registers in Ankylosing Spondylitis (BSRBR-AS) study: Protocol for a prospective cohort study of the long-term safety and quality of life outcomes of biologic treatment.
BACKGROUND: Axial spondyloarthropathy typically has its onset in early adulthood and can impact significantly on quality of life. In the UK, biologic anti-tumour necrosis factor therapy is recommended for patients who are unresponsive to non-steroidal anti-inflammatory drugs. There remain several unresolved issues about the long-term safety and quality of life outcomes of biologic treatment in axial spondyloarthropathy. Long-term "real-world" surveillance data are required to complement data from randomised controlled trials. METHODS/DESIGN: We are conducting a UK-wide prospective cohort study of patients with axial spondyloarthropathy who are naïve to biologic therapy at the time of recruitment. Those about to commence anti-tumour necrosis factor biologic therapy will enter a "biologic" sub-cohort with other patients assigned to a "non-biologic" sub-cohort. The primary objective is to determine whether the use of biologic therapy is associated with an increased risk of serious infection, while secondary objectives are to assess differences in malignancy, serious comorbidity, all-cause mortality but also assess impact on specific clinical domains (physical health, mental health and quality of life) including work outcomes between biologic and non-biologic patient cohorts. Patients will be followed-up for up to 5 years. Data are obtained at baseline and at standard clinical follow-up visits - at 3, 6 and 12 months and then annually for the biologic cohort and annually for the non-biologic cohort. This study will also collect biological samples for genetic analysis. DISCUSSION: Although biologic therapy is widely used for ankylosing spondylitis patients who are unresponsive to non-steroidal anti-inflammatory drugs, the majority of the available safety information comes from rheumatoid arthritis, where increased infection risk has consistently been shown. However, given the typical demographic differences between rheumatoid arthritis and axial spondyloarthropathy patients, it is important to develop an epidemiologically rigorous cohort of patients receiving biologic therapy to effectively evaluate outcomes with regard not only to safety but also to quantify benefits across clinical, psychosocial and work outcomes. CLINICAL TRIAL REGISTRATION: This is an observational cohort study and clinical trial registration was not required or obtained.
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Barnish M (2014). A quantitative content analysis of person-first language use in healthcare research, healthcare practice, and by support groups for people with disabilities. Open Journal of Modern Linguistics, 4, 505-511.
Conferences
Tikhonova I, Long L, Ocean N, Barnish M, Robinson S, Nikram E, Bello S, Dodman S, Hoyle M (2019). BENRALIZUMAB FOR TREATING SEVERE EOSINOPHILIC ASTHMA: NICE SINGLE TECHNOLOGY APPRAISAL.
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Barnish M, Tørnes M, Horne B (2018). Are political features associated with population health outcomes? a systematic review of internationally comparative studies. Society for Social Medicine & Population Health ASM 2018.
Varley-Campbell J, Dodman S, Coelho H, Cooper C, Barnish M, Mujica-Mota R, Hyde C, Hoyle M (2018). Full texts vs. conference abstract data, how does the message change?. HTAi 2018.
Barnish M, Tørnes M, Horne B (2018). P20 Are political features associated with population health outcomes? a systematic review of internationally comparative studies. Poster presentations.
Barnish MS, Tagiyeva N, Devereux G, Aucott L, Turner S (2017). CHANGES IN THE RELATIONSHIP BETWEEN ASTHMA AND ASSOCIATED RISK FACTORS IN CHILDREN AGED 8-13 OVER FIFTY YEARS: ECOLOGICAL STUDY FROM ABERDEEN, NORTH EAST SCOTLAND. Society for Social Medicine ASM 2017.
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Barnish MS, Atkinson RA, Barran SM, Barnish J (2017). POTENTIAL BENEFIT OF SINGING FOR PEOPLE WITH PARKINSON'S DISEASE: a SYSTEMATIC REVIEW UPDATED TO 2017. Society for Social Medicine ASM 2017.
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Zhao S, Jones GT, Barnish MS, Dean LE, Macfarlane GJ, Sengupta R, Goodson NJ (2017). SMOKING EXPOSURE IS ASSOCIATED WITH INCREASED DISEASE SEVERITY IN AXIAL SPONDYLOARTHRITIS: RESULTS FROM THE BRITISH SOCIETY FOR RHEUMATOLOGY BIOLOGICS REGISTER FOR ANKYLOSING SPONDYLITIS. Rheumatology 2017.
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Barnish MS, Morgan HM, Barnish J (2017). SYSTEMATIC REVIEW OF REVIEWS ON THE NEGATIVE HEALTH EFFECTS AND PSYCHOSEXUAL BENEFITS OF HIGH-HEELED SHOES. Society for Social Medicine ASM 2017.
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Macfarlane GJ, Barnish MS, Jones GT (2017). THE CO-OCCURRENCE OF AXIAL SPONDYLOARTHRITIS AND FIBROMYALGIA: RESULTS FROM a NATIONAL REGISTER. Rheumatology 2017.
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Barnish MS, Dean LE, Jones GT, Pathan E, Macfarlane GJ (2016). COMPARISON OF CLINICAL CHARACTERISTICS BETWEEN SMOKING AND NON-SMOKING PATIENTS WITH AXIAL SPONDYLOARTHROPATHY: a META-ANALYSIS. International Congress on Spondyloarthropathies.
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Zhao S, Jones GT, Barnish MS, Dean LE, Macfarlane GJ, Sengupta R, Goodson N (2016). INCREASED SMOKING EXPOSURE IS ASSOCIATED WITH INCREASED DISEASE SEVERITY IN AXIAL SPONDYLOARTHRITIS: RESULTS FROM THE BRITISH SOCIETY FOR RHEUMATOLOGY BIOLOGICS REGISTER FOR ANKYLOSING SPONDYLITIS (BSRBR-AS). International Congress on Spondyloarthropathies.
Author URL.
Macfarlane GJ, Barnish MS, Jones GT (2016). The Co-Occurrence of Axial Spondyloarthritis and Fibromyalgia: a National Register-Based Study. American College of Rheumatology 2016.
Author URL.
Jones GT, Barnish MS, Dean LE, Keat A, Pathan E, Macfarlane GJ (2016). WHO ARE WE TREATING WITH TNF INHIBITION? RESULTS FROM THE BRITISH SOCIETY FOR RHEUMATOLOGY BIOLOGICS REGISTER IN ANKYLOSING SPONDYLITIS (BSRBR-AS). Rheumatology 2016.
Author URL.
Turner S, Barnish MS, Tagiyeva N, Devereux G, Aucott L (2015). An ecological survey of time trends and associated risk factors for childhood asthma in Aberdeen 1964-2014.
Author URL.
Barnish M, Jones GT, Dean LE, Keat A, Pathan E, Macfarlane GJ (2015). WHO ARE WE TREATING WITH TNF INHIBITION? RESULTS FROM THE BRITISH SOCIETY FOR RHEUMATOLOGY BIOLOGICS REGISTER IN ANKYLOSING SPONDYLITIS (BSRBR-AS). Scottish Society for Rheumatology Winter Meeting.
Barnish MS, Horton SMC, Butterfint ZR, Deane KHO (2013). Relationships between cognitive status and speech, language and communication impairments in Parkinson's disease: a systematic review. International Congress of Parkinson's Disease and Movement Disorders.
Author URL.
Barnish MS, Horton SMC, Butterfint ZR, Deane KHO (2013). Relationships between cognitive status, speech characteristics and communicative participation in Parkinson's disease. International Congress of Parkinson's Disease and Movement Disorders.
Author URL.
Barnish M (2012). Acoustic speech characteristics of British people with Parkinson's disease: preliminary results. Parkinson's UK Research Conference 2012.
Barnish M, Horton S, Butterfint Z, Deane KHO (2012). Relationships between cognitive status and communicative participation in Parkinson's disease: preliminary results. Parkinson's UK Research Conference 2012.
Barnish M, Horton S, Butterfint Z, Deane KHO (2012). Relationships between cognitive status and impairments of spoken communication in Parkinson's disease: a systematic review. Parkinson's UK Research Conference 2012.
Barnish M, Horton S, Butterfint Z, Deane KHO (2012). Relationships between cognitive status and language impairments in Parkinson's disease: a systematic review. Parkinson's UK Research Conference 2012.
Barnish M, Butterfint Z, Horton S, Deane KHO (2012). Relationships between cognitive status and speech characteristics in Parkinson's disease: a systematic review. Parkinson's UK Research Conference 2012.
Reports
Tikhonova I, Long L, Ocean N, Barnish M, Robinson S, Nikram E, Bello S, Dodman S, Halpin D, Hoyle M, et al (2018). Benralizumab for treating severe asthma: a Single Technology Appraisal.
Barnish M, Varley-Campbell J, Coelho H, Dodman S, Snowsill T, Mujica-Mota R, Packman D, Ocean N, Kay T, Liversedge N, et al (2018). Biomarker tests to help diagnose preterm labour in symptomatic women with intact membranes: a systematic review.
Varley-Campbell J, Mujica-Mota R, Coelho H, Ocean N, Barnish M, Packman D, Dodman S, Cooper C, Snowsill T, Kay T, et al (2018). Biomarker tests to help diagnose preterm labour in women with intact membranes. NICE.
Griffin E, Barnish M, Packman D, Coelho H, Matthews J, Dodman S, Robinson S, Dangoor A, Dorey N, Hoyle M, et al (2018). Brigatinib for treating ALK-positive non-small-cell lung cancer after crizotinib: a Single Technology Appraisal. NICE.
Barnish M, Morgan HM (2017). Apakah hak tinggi buruk bagi kesehatan? Dua ahli menelaah buktinya. The Conversation Indonesia.
Barnish M, Morgan HM (2017). Are high heels bad for your health? Two experts review the evidence. The Conversation.
Morgan HM, Barnish M (2017). High heels at work: does the law need reformed?. University of Aberdeen School of Law.
Barnish M (2013). Relationships between cognitive status, speech impairment and communicative participation in Parkinson’s disease. University of East Anglia.
Barnish M (eds)(2013). Relationships between cognitive status, speech impairment and communicative participation in Parkinson’s disease.
Publications by year
2023
Jones ML, Barnish MS, Hughes RR, Murray AK, Mansour O, Loni T, Vickery HM, Evans ML, Green L, Verdezoto N, et al (2023). Exploring the potential of using simulation games for engaging with sheep farmers about lameness recognition.
Front Vet Sci,
10Abstract:
Exploring the potential of using simulation games for engaging with sheep farmers about lameness recognition.
INTRODUCTION: Computer simulation games are increasingly being used in agriculture as a promising tool to study, support and influence real-life farming practices. We explored the potential of using simulation games to engage with sheep farmers on the ongoing challenge of reducing lameness. Working with UK stakeholders, we developed a game in which players are challenged with identifying all the lame sheep in a simulated flock. Here, we evaluate the game's potential to act as a tool to help assess, train and understand farmers' ability to recognize the early signs of lameness. METHODS: Participants in the UK were invited to play the game in an online study, sharing with us their in-game scores alongside information relating to their real-life farming experience, how they played the game, and feedback on the game. Mixed methods were used to analyze this information in order to evaluate the game. Quantitative analyses consisted of linear modeling to test for statistical relationships between participants' in-game recall (% of the total number of lame sheep that were marked as lame), and the additional information they provided. Qualitative analyses of participants' feedback on the game consisted of thematic analysis and a Likert Scale questionnaire to contextualize the quantitative results and identify additional insights from the study. RESULTS: Quantitative analyses identified no relationships between participants' (n = 63) recall scores and their real life farming experience, or the lameness signs they looked for when playing the game. The only relationship identified was a relationship between participants' recall score and time spent playing the game. Qualitative analyses identified that participants did not find the game sufficiently realistic or engaging, though several enjoyed playing it and saw potential for future development. Qualitative analyses also identified several interesting and less-expected insights about real-life lameness recognition practices that participants shared after playing the game. DISCUSSION: Simulation games have potential as a tool in livestock husbandry education and research, but achieving the desired levels of realism and/or engagingness may be an obstacle to realizing this. Future research should explore this potential further, aided by larger budgets and closer collaboration with farmers, stockpeople, and veterinarians.
Abstract.
Author URL.
Barnish MS, Nelson-Horne RV (2023). Group-based active artistic interventions for adults with primary anxiety and depression: a systematic review.
BMJ Open,
13(6), e069310-e069310.
Abstract:
Group-based active artistic interventions for adults with primary anxiety and depression: a systematic review
ObjectivesThis systematic review examined the potential benefit of all group-based performing arts interventions for primary anxiety and/or depression.SettingScholarly literature from any country or countries globally.Data sourcesThree key bibliographic databases, Google Scholar and relevant citation chasing.Primary and secondary outcome measuresDepression and/or anxiety symptom severity, well-being, quality of life, functional communication or social participation.ResultsDatabase searches returned a total of 63 678 records, of which 56 059 remained following dededuplication. From these database searches, a total of 153 records proceeded to full-text screening. These were supplemented by 18 additional unique full-text screening records from Google Scholar searches and citation chasing (12% of total). From a total of 171 records at the full-text screening stage, 12 publications (7%) were eligible for inclusion in this systematic review, each reporting on a separate study. Published from 2004 to 2021, these studies involved a total of 669 participants with anxiety and/or depression from nine countries and covered five broad artistic modalities: dance, music therapy, art therapy, martial arts and theatre. Dance was the most studied artistic modality (five studies), while there were three studies on art therapy, two on music therapy and one each on martial arts and theatre. The evidence was clearest for a benefit of arts therapies on depression and/or anxiety symptoms.ConclusionsThis systematic review addresses all group-based active arts interventions in a focused population of primary anxiety and/or depression. The evidence suggests that the arts may be a useful therapeutic medium in this population. However, a substantial limitation of the evidence base is the lack of studies directly comparing different artistic modalities. Moreover, not all artistic modalities were assessed for all outcome domains. Therefore, it is not currently possible to determine which artistic modalities are most beneficial for which specific outcomes.
Abstract.
2021
Barnish MS, Tan SY, Taeihagh A, Tørnes M, Nelson-Horne RVH, Melendez-Torres GJ (2021). Linking political exposures to child and maternal health outcomes: a realist review.
BMC Public Health,
21(1).
Abstract:
Linking political exposures to child and maternal health outcomes: a realist review
Background: Conceptual and theoretical links between politics and public health are longstanding. Internationally comparative systematic review evidence has shown links between four key political exposures – the welfare state, political tradition, democracy and globalisation – on population health outcomes. However, the pathways through which these influences may operate have not been systematically appraised. Therefore, focusing on child and maternal health outcomes, we present a realist re-analysis of the dataset from a recent systematic review. Methods: the database from a recent systematic review on the political determinants of health was used as the data source for this realist review. Included studies from the systematic review were re-evaluated and those relating to child and/or maternal health outcomes were included in the realist synthesis. Initial programme theories were generated through realist engagement with the prior systematic review. These programme theories were adjudicated and refined through detailed engagement with the evidence base using a realist re-synthesis involving two independent reviewers. The revised theories that best corresponded to the evidence base formed the final programme theories. Results: Out of the 176 included studies from the systematic review, a total of 67 included child and/or maternal health outcomes and were included in the realist re-analysis. Sixty-three of these studies were ecological and data were collected between 1950 and 2014. Six initial programme theories were generated. Following theory adjudication, three theories in revised form were supported and formed the final programme theories. These related to a more generous welfare state leading to better child and maternal health especially in developed countries through progressive social welfare policies, left-of-centre political tradition leading to lower child mortality and low birth weight especially in developed countries through greater focus on welfare measures, and increased globalisation leading to greater child and infant mortality and youth smoking rates in LMECs through greater influence of multinational corporations and neoliberal trade organisations. Conclusion: We present a realist re-analysis of a large systematically identified body of evidence on how four key political exposures – the welfare state, democracy, political tradition and globalisation – relate to child and maternal health outcomes. Three final programme theories were supported.
Abstract.
2020
Barnish MS, Barran SM (2020). A systematic review of active group-based dance, singing, music therapy and theatrical interventions for quality of life, functional communication, speech, motor function and cognitive status in people with Parkinson’s disease.
BMC Neurology,
20(1).
Abstract:
A systematic review of active group-based dance, singing, music therapy and theatrical interventions for quality of life, functional communication, speech, motor function and cognitive status in people with Parkinson’s disease
Abstract
. Background
. Parkinson’s disease (PD) is a common neurodegenerative condition associated with a wide range of motor and non-motor symptoms. There has been increasing interest in the potential benefit of performing arts as a therapeutic medium in PD. While there have been previous reviews, none have considered all performing arts modalities and most have focused on dance. This systematic review examined the potential benefit of all active group-based performing arts interventions for quality of life, functional communication, speech, motor function and cognitive status.
.
. Methods
. Searches were conducted in February 2020 on five scholarly databases. Supplementary searches were conducted. Included studies were quantitative in design, and assessed the potential benefit of any active group-based performing arts intervention for quality of life, functional communication, speech, motor function or cognitive status in people with PD. Full text papers were eligible for inclusion, as were conference abstracts since January 2018. Screening, data extraction, narrative synthesis and quality assessment were conducted independently by two reviewers. Quality assessment used the SURE checklists.
.
. Results
. Fifty-six studies were eligible for inclusion in this systematic review, reported in 67 publications. Published from 1989 to 2020, these studies included a total of 1531 people with PD from 12 countries, and covered four broad performing arts modalities: dance, singing, music therapy and theatre. Dance remains the most commonly studied performing arts modality for PD (38 studies), while there were 12 studies on singing interventions, four on music therapy, and only two on theatrical interventions. There was evidence for a beneficial effect of all four performing arts modalities on at least some outcome domains.
.
. Conclusions
. This is the first systematic review to assess the potential benefit of all active group-based performing arts interventions in PD. The evidence suggests that performing arts may be a useful therapeutic medium in PD. However, a substantial limitation of the evidence base is that no studies compared interventions from different performing arts modalities. Moreover, not all performing arts modalities were assessed for all outcome domains. Therefore it is not currently possible to determine which performing arts modalities are most beneficial for which specific outcomes.
.
Abstract.
2019
Tikhonova I, Long L, Ocean N, Barnish M, Robinson S, Nikram E, Bello S, Dodman S, Hoyle M (2019). BENRALIZUMAB FOR TREATING SEVERE EOSINOPHILIC ASTHMA: NICE SINGLE TECHNOLOGY APPRAISAL.
Author URL.
Barnish M, Daley DJ, Deane KHO, Clark AB, Gray RJ, Horton SMC, Butterfint ZR, Myint PK (2019). Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease. Medical Journal of the Islamic Republic of Iran, 33
Barnish M, Daley DJ, Deane KHO, Clark AB, Gray RJ, Horton SMC, Butterfint ZR, Myint PK (2019). Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease.
Medical Journal of the Islamic Republic of Iran,
33(1), 1-5.
Abstract:
Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease
Background: the Montreal Cognitive Assessment (MoCA) has been recommended as a cognitive screening tool for clinical practice and research in Parkinson's disease (PD), yet no normative data have been published for MoCA in PD without dementia. Methods: We undertook a pooled secondary analysis of data from two studies (one cross-sectional design and one clinical trial) conducted in the East of England region. All participants were aged 18 years or over, met UK Brain Bank criteria for PD and did not have clinical dementia. Cognitive status was assessed using MoCA at baseline in both studies. The influences of age, gender, disease duration, medication load (LEDD) and mood (HADS) on cognition were examined using regression analysis. Results: Data from 101 people with PD without dementia were available (mean age 71 years, 66% men). Median (IQR) MoCA was 25(22, 27). Age was found as the only predictor of MoCA in this sample. People aged over 71 had poorer MoCA (Beta=0.6 (95%CI 0.44, 0.82)) and an increased odds of MoCA < 26 (Beta=0.29 (95%CI 0.12, 0.70)) as well as poorer scores on several MoCA sub-domains. Conclusion: We present the normative data for MoCA in people with PD without clinical dementia. Age appeared to be the only associated factor for lower level of cognition, suggestive of Mild cognitive impairment in PD (PD-MCI) in PD without clinical diagnosis of dementia.
Abstract.
Barnish M, Daley DJ, Deane KH, Clark AB, Gray RJ, Horton SM, Butterfint ZR, Myint PK (2019). Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease.
Med J Islam Repub Iran,
33Abstract:
Cognitive profile and determinants of poor cognition in people without dementia in Parkinson's disease.
Background: the Montreal Cognitive Assessment (MoCA) has been recommended as a cognitive screening tool for clinical practice and research in Parkinson's disease (PD), yet no normative data have been published for MoCA in PD without dementia. Methods: We undertook a pooled secondary analysis of data from two studies (one cross-sectional design and one clinical trial) conducted in the East of England region. All participants were aged 18 years or over, met UK Brain Bank criteria for PD and did not have clinical dementia. Cognitive status was assessed using MoCA at baseline in both studies. The influences of age, gender, disease duration, medication load (LEDD) and mood (HADS) on cognition were examined using regression analysis. Results: Data from 101 people with PD without dementia were available (mean age 71 years, 66% men). Median (IQR) MoCA was 25(22, 27). Age was found as the only predictor of MoCA in this sample. People aged over 71 had poorer MoCA (Beta=0.6 (95%CI 0.44, 0.82)) and an increased odds of MoCA
Abstract.
Author URL.
Whibley D, AlKandari N, Kristensen K, Barnish M, Rzewuska M, Druce KL, Tang NKY (2019). Sleep and Pain: a Systematic Review of Studies of Mediation.
Clin J Pain,
35(6), 544-558.
Abstract:
Sleep and Pain: a Systematic Review of Studies of Mediation.
OBJECTIVES: a relationship between sleep and pain is well established. A better understanding of the mechanisms that link sleep and pain intensity is urgently needed to optimize pain management interventions. The objective of this systematic review was to identify, synthesize, and critically appraise studies that have investigated putative mediators on the path between sleep and pain intensity. METHODS: a systematic search of 5 electronic bibliographic databases (EMBASE, MEDLINE, CINAHL, PsycINFO, and the Cochrane Central Register of Controlled Trials) was conducted. Eligible studies had to apply a formal test of mediation to variables on the path between a sleep variable and pain intensity or vice versa. All searches, data extraction and quality assessment were conducted by at least 2 independent reviewers. RESULTS: the search yielded 2839 unique articles, 9 of which were eligible. of 13 mediation analyses, 11 investigated pathways from a sleep variable to pain intensity. Putative mediators included affect/mood, depression and/or anxiety, attention to pain, pain helplessness, stress, fatigue, and physical activity. Two analyses investigated pathways from pain intensity to a sleep variable, examining the potentially mediating role of depressive symptoms and mood. Although evidence supported a mediating role for psychological and physiological aspects of emotional experiences and attentional processes, methodological limitations were common, including use of cross-sectional data and minimal adjustment for potential confounders. DISCUSSION: a growing body of research is applying mediation analysis to elucidate mechanistic pathways between sleep and pain intensity. Currently sparse evidence would be illuminated by more intensively collected longitudinal data and improvements in analysis.
Abstract.
Author URL.
Varley-Campbell J, Mujica Mota R, Coelho H, Ocean N, Barnish M, Packman D, Dodman S, Cooper C, Snowsill TM, Kay T, et al (2019). Three biomarker tests to help diagnose preterm labour: a systematic review and economic evaluation. Health Technology Assessment, 23(13).
2018
Barnish M, Tørnes M, Horne B (2018). Are political features associated with population health outcomes? a systematic review of internationally comparative studies. Society for Social Medicine & Population Health ASM 2018.
Tikhonova I, Long L, Ocean N, Barnish M, Robinson S, Nikram E, Bello S, Dodman S, Halpin D, Hoyle M, et al (2018). Benralizumab for treating severe asthma: a Single Technology Appraisal.
Barnish M, Varley-Campbell J, Coelho H, Dodman S, Snowsill T, Mujica-Mota R, Packman D, Ocean N, Kay T, Liversedge N, et al (2018). Biomarker tests to help diagnose preterm labour in symptomatic women with intact membranes: a systematic review.
Varley-Campbell J, Mujica-Mota R, Coelho H, Ocean N, Barnish M, Packman D, Dodman S, Cooper C, Snowsill T, Kay T, et al (2018). Biomarker tests to help diagnose preterm labour in women with intact membranes. NICE.
Griffin E, Barnish M, Packman D, Coelho H, Matthews J, Dodman S, Robinson S, Dangoor A, Dorey N, Hoyle M, et al (2018). Brigatinib for treating ALK-positive non-small-cell lung cancer after crizotinib: a Single Technology Appraisal. NICE.
Varley-Campbell J, Dodman S, Coelho H, Cooper C, Barnish M, Mujica-Mota R, Hyde C, Hoyle M (2018). Full texts vs. conference abstract data, how does the message change?. HTAi 2018.
Barnish M, Tørnes M, Nelson-Horne B (2018). How much evidence is there that political factors are related to population health outcomes? an internationally comparative systematic review. BMJ Open, 8, e020886-e020886.
Varley-Campbell J, Cooper C, Coelho H, Dodman S, Barnish M, Mujica-Mota R, Hyde C, Hoyle M (2018). OP136 Full Texts Versus Conference Abstract Data: How Does the Message Change?. International Journal of Technology Assessment in Health Care, 34(S1), 50-51.
Barnish M, Tørnes M, Horne B (2018). P20 Are political features associated with population health outcomes? a systematic review of internationally comparative studies. Poster presentations.
Barnish M (2018). The inclusion of retracted studies in systematic reviews: a response to Gray et al. (2018). International Journal of Nursing Studies, 80, 90-91.
2017
Barnish M, Morgan HM (2017). Apakah hak tinggi buruk bagi kesehatan? Dua ahli menelaah buktinya. The Conversation Indonesia.
Barnish M, Morgan HM (2017). Are high heels bad for your health? Two experts review the evidence. The Conversation.
Barnish MS, Tagiyeva N, Devereux G, Aucott L, Turner S (2017). CHANGES IN THE RELATIONSHIP BETWEEN ASTHMA AND ASSOCIATED RISK FACTORS IN CHILDREN AGED 8-13 OVER FIFTY YEARS: ECOLOGICAL STUDY FROM ABERDEEN, NORTH EAST SCOTLAND. Society for Social Medicine ASM 2017.
Author URL.
Barnish MS, Tagiyeva N, Devereux G, Aucott L, Turner S (2017). Changes in the relationship between asthma and associated risk factors over fifty years.
Pediatric Allergy and Immunology,
28(2), 162-169.
Abstract:
Changes in the relationship between asthma and associated risk factors over fifty years
Background: Childhood asthma is a common condition whose prevalence is changing. We hypothesized that the relationship between asthma and associated risk factors has changed over a 50-year period. Methods: an ecological study design was used. Children aged 8–13 attending schools in Aberdeen city were surveyed on seven occasions between 1964 and 2014. The following were determined: history of asthma, history of eczema, parental smoking, parental asthma, sex and socio-economic status. Analysis was by a structural change model with two knots. The outcome reported was the change in odds ratio between asthma and a given risk factor during a given period. Results: There were 23,241 questionnaires distributed and 17,439 returned (75%). The odds ratio (OR) for a child with asthma to have eczema increased between 1989 and 1999 by 1.031 [95% CI 1.028, 1.035] and by 1.042 between 2004 and 2014 [1.038, 1.047]. The OR for a child with asthma to have a parent who smoked rose by 1.032 [1.028, 1.036] between 1989 and 1999 and by 1.043 [1.038, 1.047] between 2004 and 2014), and to have a parent with asthma (1.027 [1.022, 1.031] for 1994–99 and 1.042 [1.037, 1.048] for 2004–2014). The OR for a child with asthma being male, but not and being from the most deprived communities, rose between 1989–1999 and 2004–2014. Conclusions: the relationship between asthma prevalence and particular risk factors changed over the 50-year period of study, and this might reflect changes in children's environment and/or susceptibility.
Abstract.
Macfarlane GJ, Barnish MS, Pathan E, Martin KR, Haywood KL, Siebert S, Packham J, Atzeni F, Jones GT (2017). Co‐Occurrence and Characteristics of Patients with Axial Spondyloarthritis Who Meet Criteria for Fibromyalgia.
Arthritis & Rheumatology,
69(11), 2144-2150.
Abstract:
Co‐Occurrence and Characteristics of Patients with Axial Spondyloarthritis Who Meet Criteria for Fibromyalgia
ObjectiveTo estimate the proportion of patients with axial spondyloarthritis (SpA) in a UK national biologics registry who met criteria for fibromyalgia (FM), and to delineate the characteristics of these patients.MethodsTwo cohorts of patients are prospectively recruited from across 83 centers in the UK for the British Society for Rheumatology Biologics Register in Ankylosing Spondylitis (BSRBR‐AS). All patients are required to meet Assessment of SpondyloArthritis international Society (ASAS) criteria for axial SpA. Patients are either newly starting biologic therapy (biologics cohort) or are naive to treatment with biologic agents (non‐biologics cohort) at the time of recruitment, and all patients are followed up prospectively. At recruitment and follow‐up, clinical information and measurements are recorded while patients complete the 2011 research criteria for FM and assessments of the level of disease activity and work impact.ResultsOf the patients registered in the BSRBR‐AS, 1,504 (68% male) were eligible for the current analysis, of whom 311 (20.7%) met the 2011 research criteria for FM. Prevalence of FM was similar between patients who fulfilled the modified New York criteria for AS (19.7%) and those who fulfilled ASAS imaging criteria but not the modified New York criteria (25.2%); however, among those who fulfilled only the ASAS clinical criteria, the prevalence of FM was lower (9.5%). Patients who met FM criteria reported significantly worse disease activity, function, global severity scores, and quality of life, and were more likely to have moderate or severe levels of mood disorder and clinically important fatigue. Patients who met FM criteria reported experiencing work impairment around half their working time. Meeting FM criteria was not related to elevated C‐reactive protein levels or most extraspinal manifestations, but was associated with a higher likelihood of having received biologic therapy.ConclusionDeveloping management approaches that would address the significant unmet clinical needs of the 1 in 5 patients with axial SpA who meet criteria for FM should be a research priority.
Abstract.
Morgan HM, Barnish M (2017). High heels at work: does the law need reformed?. University of Aberdeen School of Law.
Barnish MS, Atkinson RA, Barran SM, Barnish J (2017). POTENTIAL BENEFIT OF SINGING FOR PEOPLE WITH PARKINSON'S DISEASE: a SYSTEMATIC REVIEW UPDATED TO 2017. Society for Social Medicine ASM 2017.
Author URL.
Macfarlane GJ, Barnish MS, Jones GT (2017). Persons with chronic widespread pain experience excess mortality: longitudinal results from UK Biobank and meta-analysis.
Ann Rheum Dis,
76(11), 1815-1822.
Abstract:
Persons with chronic widespread pain experience excess mortality: longitudinal results from UK Biobank and meta-analysis.
OBJECTIVE: it is uncertain whether persons with chronic widespread pain (CWP) experience premature mortality. Using the largest study conducted, we determine whether such a relationship exists, estimate its magnitude and establish what factors mediate any relationship. METHODS: UK Biobank, a cohort study of 0.5 million people aged 40-69 years, recruited throughout Great Britain in 2006-2010. Participants reporting 'pain all over the body' for >3 months were compared with persons without chronic pain. Information on death (with cause) was available until mid-2015. We incorporated these results in a meta-analysis with other published reports to calculate a pooled estimate of excess risk. RESULTS: 7130 participants reported CWP and they experienced excess mortality (mortality risk ratio 2.43, 95%CI 2.17 to 2.72). Specific causes of death in excess were cancer (1.73adjusted age and sex, 95% CI 1.46 to 2.05), cardiovascular (3.24adjusted age and sex, 95% CI 2.55 to 4.11), respiratory (5.66adjusted age and sex, 95% CI 4.00 to 8.03) and other disease-related causes (4.04adjusted age and sex, 95% CI 3.05 to 5.34). Excess risk was substantially reduced after adjustment for low levels of physical activity, high body mass index, poor quality diet and smoking. In meta-analysis, all studies showed significant excess all-cause (combined estimate 1.59 (95% CI 1.05 to 2.42)), cardiovascular and cancer mortality. CONCLUSIONS: Evidence is now clear that persons with CWP experience excess mortality. UK Biobank results considerably reduce uncertainty around the magnitude of excess risk and are consistent with the excess being explained by adverse lifestyle factors, which could be targeted in the management of such patients.
Abstract.
Author URL.
Zhao S, Jones GT, Barnish MS, Dean LE, Macfarlane GJ, Sengupta R, Goodson NJ (2017). SMOKING EXPOSURE IS ASSOCIATED WITH INCREASED DISEASE SEVERITY IN AXIAL SPONDYLOARTHRITIS: RESULTS FROM THE BRITISH SOCIETY FOR RHEUMATOLOGY BIOLOGICS REGISTER FOR ANKYLOSING SPONDYLITIS. Rheumatology 2017.
Author URL.
Barnish MS, Morgan HM, Barnish J (2017). SYSTEMATIC REVIEW OF REVIEWS ON THE NEGATIVE HEALTH EFFECTS AND PSYCHOSEXUAL BENEFITS OF HIGH-HEELED SHOES. Society for Social Medicine ASM 2017.
Author URL.
Barnish MS, Horton SMC, Butterfint ZR, Clark AB, Atkinson RA, Deane KHO (2017). Speech and communication in Parkinson’s disease: a cross-sectional exploratory study in the UK. BMJ Open, 7(5), e014642-e014642.
Macfarlane GJ, Barnish MS, Jones GT (2017). THE CO-OCCURRENCE OF AXIAL SPONDYLOARTHRITIS AND FIBROMYALGIA: RESULTS FROM a NATIONAL REGISTER. Rheumatology 2017.
Author URL.
Barnish M, Morgan HM, Barnish J (2017). The 2016 HIGh Heels: Health effects and psychosexual BenefITS (HIGH HABITS) study: systematic review of reviews and additional primary studies. BMC Public Health, 18(1).
Reynolds SE, Richardson SV, Barnish M, Reid I, Ross R, Campbell R, Horne B (2017). The Politics of Women’s Fashion in the Cultural West: a Perspective. Art and Design Review, 5, 252-257.
Barnish MS, Turner S (2017). The value of pragmatic and observational studies in health care and public health.
Pragmat Obs Res,
8, 49-55.
Abstract:
The value of pragmatic and observational studies in health care and public health.
Evidence-based practice is an important component of health care service delivery. However, there is a tendency, embodied in tools such as Grades of Recommendation, Assessment, Development, and Evaluation, to focus principally on the classification of study design, at the expense of a detailed assessment of the strengths and limitations of the individual study. Randomized controlled trials (RCTs), and in particular the classical "explanatory" RCT, have a privileged place in the hierarchy of evidence. However, classical RCTs have substantial limitations, most notably a lack of generalizability, which limit their direct applicability to clinical practice implementation. Pragmatic and observational studies can provide an invaluable perspective into real-world applicability. This evidence could be used more widely to complement ideal-condition results from classical RCTs, following the principle of triangulation. In this review article, we discuss several types of pragmatic and observational studies that could be used in this capacity. We discuss their particular strengths and how their limitations may be overcome and provide real-life examples by means of illustration.
Abstract.
Author URL.
2016
Barnish MS, Dean LE, Jones GT, Pathan E, Macfarlane GJ (2016). COMPARISON OF CLINICAL CHARACTERISTICS BETWEEN SMOKING AND NON-SMOKING PATIENTS WITH AXIAL SPONDYLOARTHROPATHY: a META-ANALYSIS. International Congress on Spondyloarthropathies.
Author URL.
Barnish MS, Barnish J (2016). High-heeled shoes and musculoskeletal injuries: a narrative systematic review.
BMJ Open,
6(1).
Abstract:
High-heeled shoes and musculoskeletal injuries: a narrative systematic review.
OBJECTIVES: to conduct the first systematic review from an epidemiological perspective regarding the association between high-heeled shoe wear and hallux valgus, musculoskeletal pain, osteoarthritis (OA) and both first-party and second-party injury in human participants without prior musculoskeletal conditions. SETTING: a systematic review of international peer-reviewed scientific literature across seven major languages. DATA SOURCES: Searches were conducted on seven major bibliographic databases in July 2015 to initially identify all scholarly articles on high-heeled shoes. Supplementary manual searches were conducted. Titles, abstracts and full-text articles were sequentially screened to identify all articles assessing epidemiological evidence regarding the association between high-heeled shoe wear and hallux valgus, musculoskeletal pain, OA and both first-party and second-party injury in human participants without prior musculoskeletal conditions. Standardised data extraction and quality assessment (Threats to Validity tool) were conducted. PRIMARY AND SECONDARY OUTCOME MEASURES: Musculoskeletal pain or OA as assessed by clinical diagnosis or clinical assessment tool. First-party or second-party injury. RESULTS: 644 unique records were identified, 56 full-text articles were screened and 18 studies included in the review. Four studies assessed the relationship with hallux valgus and three found a significant association. Two studies assessed the association with OA and neither found a significant association. Five studies assessed the association with musculoskeletal pain and three found a significant association. Eight studies assessed first-party injury and seven found evidence of a significant injury toll associated with high-heeled shoes. One study provided data on second-party injury and the injury toll was low. CONCLUSIONS: High-heeled shoes were shown to be associated with hallux valgus, musculoskeletal pain and first-party injury. No conclusive evidence regarding OA and second-party injury was found. Societal and clinical relevance of these findings is discussed. Concern is expressed about the expectation to wear high-heeled shoes in some work and social situations and access by children.
Abstract.
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Zhao S, Jones GT, Barnish MS, Dean LE, Macfarlane GJ, Sengupta R, Goodson N (2016). INCREASED SMOKING EXPOSURE IS ASSOCIATED WITH INCREASED DISEASE SEVERITY IN AXIAL SPONDYLOARTHRITIS: RESULTS FROM THE BRITISH SOCIETY FOR RHEUMATOLOGY BIOLOGICS REGISTER FOR ANKYLOSING SPONDYLITIS (BSRBR-AS). International Congress on Spondyloarthropathies.
Author URL.
Barnish J, Atkinson RA, Barran SM, Barnish MS (2016). Potential Benefit of Singing for People with Parkinson's Disease: a Systematic Review.
JOURNAL OF PARKINSONS DISEASE,
6(3), 473-484.
Author URL.
Barnish MS, Whibley D, Horton SMC, Butterfint ZR, Deane KHO (2016). Roles of Cognitive Status and Intelligibility in Everyday Communication in People with Parkinson's Disease: a Systematic Review.
JOURNAL OF PARKINSONS DISEASE,
6(3), 453-462.
Author URL.
Macfarlane GJ, Barnish MS, Jones GT (2016). The Co-Occurrence of Axial Spondyloarthritis and Fibromyalgia: a National Register-Based Study. American College of Rheumatology 2016.
Author URL.
Jones GT, Barnish MS, Dean LE, Keat A, Pathan E, Macfarlane GJ (2016). WHO ARE WE TREATING WITH TNF INHIBITION? RESULTS FROM THE BRITISH SOCIETY FOR RHEUMATOLOGY BIOLOGICS REGISTER IN ANKYLOSING SPONDYLITIS (BSRBR-AS). Rheumatology 2016.
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2015
Turner S, Barnish MS, Tagiyeva N, Devereux G, Aucott L (2015). An ecological survey of time trends and associated risk factors for childhood asthma in Aberdeen 1964-2014.
Author URL.
Barnish MS, Tagiyeva N, Devereux G, Aucott L, Turner S (2015). Diverging prevalences and different risk factors for childhood asthma and eczema: a cross-sectional study.
BMJ Open,
5(6).
Abstract:
Diverging prevalences and different risk factors for childhood asthma and eczema: a cross-sectional study.
OBJECTIVE: to compare the prevalences of and risk factors for asthma, wheeze, hay fever and eczema in primary schoolchildren in Aberdeen in 2014. DESIGN: Cross-sectional survey. SETTING: Primary schools in Aberdeen, North-East Scotland. PARTICIPANTS: Children in Scottish school years primary 1-7 were handed a questionnaire by their class teacher to be completed by their parents and returned to the researchers by post or online. MAIN OUTCOME MEASURES: Lifetime history of asthma, eczema and hay fever, and recent history of wheeze. RESULTS: 41 schools agreed to participate (87%). 11,249 questionnaires were distributed and 3935 returned (35%). A parent-reported lifetime history of asthma, eczema and hay fever was present in 14%, 30% and 24% of children, respectively. The odds of lifetime asthma increased with age (OR 1.1 per year, 95% CI 1.1 to 1.2), male sex (OR 1.89, 95% CI 1.4 to 2.3), parental smoking (OR 1.7, 95% CI 1.2 to 2.3) and eczema (OR 6.6, 95% CI 5.2 to 8.4). Prevalence of recent wheeze was also reported to be 14% and was positively associated with male sex, parental smoking and eczema. In contrast, parental eczema was the only identified predictor of childhood eczema risk. CONCLUSIONS: the lifetime prevalence of asthma in primary schoolchildren was 14% in this survey, approximately half the prevalence of eczema. We report diverging prevalences in relation to previous studies in our locality, and different risk factors for asthma and eczema. These findings suggest that asthma and eczema are unlikely to have a common origin.
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Macfarlane GJ, Barnish MS, Jones EA, Kay L, Keat A, Meldrum KT, Pathan E, Sturrock RD, Zabke C, McNamee P, et al (2015). The British Society for Rheumatology Biologics Registers in Ankylosing Spondylitis (BSRBR-AS) study: Protocol for a prospective cohort study of the long-term safety and quality of life outcomes of biologic treatment.
BMC Musculoskelet Disord,
16Abstract:
The British Society for Rheumatology Biologics Registers in Ankylosing Spondylitis (BSRBR-AS) study: Protocol for a prospective cohort study of the long-term safety and quality of life outcomes of biologic treatment.
BACKGROUND: Axial spondyloarthropathy typically has its onset in early adulthood and can impact significantly on quality of life. In the UK, biologic anti-tumour necrosis factor therapy is recommended for patients who are unresponsive to non-steroidal anti-inflammatory drugs. There remain several unresolved issues about the long-term safety and quality of life outcomes of biologic treatment in axial spondyloarthropathy. Long-term "real-world" surveillance data are required to complement data from randomised controlled trials. METHODS/DESIGN: We are conducting a UK-wide prospective cohort study of patients with axial spondyloarthropathy who are naïve to biologic therapy at the time of recruitment. Those about to commence anti-tumour necrosis factor biologic therapy will enter a "biologic" sub-cohort with other patients assigned to a "non-biologic" sub-cohort. The primary objective is to determine whether the use of biologic therapy is associated with an increased risk of serious infection, while secondary objectives are to assess differences in malignancy, serious comorbidity, all-cause mortality but also assess impact on specific clinical domains (physical health, mental health and quality of life) including work outcomes between biologic and non-biologic patient cohorts. Patients will be followed-up for up to 5 years. Data are obtained at baseline and at standard clinical follow-up visits - at 3, 6 and 12 months and then annually for the biologic cohort and annually for the non-biologic cohort. This study will also collect biological samples for genetic analysis. DISCUSSION: Although biologic therapy is widely used for ankylosing spondylitis patients who are unresponsive to non-steroidal anti-inflammatory drugs, the majority of the available safety information comes from rheumatoid arthritis, where increased infection risk has consistently been shown. However, given the typical demographic differences between rheumatoid arthritis and axial spondyloarthropathy patients, it is important to develop an epidemiologically rigorous cohort of patients receiving biologic therapy to effectively evaluate outcomes with regard not only to safety but also to quantify benefits across clinical, psychosocial and work outcomes. CLINICAL TRIAL REGISTRATION: This is an observational cohort study and clinical trial registration was not required or obtained.
Abstract.
Author URL.
Barnish M, Jones GT, Dean LE, Keat A, Pathan E, Macfarlane GJ (2015). WHO ARE WE TREATING WITH TNF INHIBITION? RESULTS FROM THE BRITISH SOCIETY FOR RHEUMATOLOGY BIOLOGICS REGISTER IN ANKYLOSING SPONDYLITIS (BSRBR-AS). Scottish Society for Rheumatology Winter Meeting.
2014
Barnish M (2014). A quantitative content analysis of person-first language use in healthcare research, healthcare practice, and by support groups for people with disabilities. Open Journal of Modern Linguistics, 4, 505-511.
2013
Barnish MS, Horton SMC, Butterfint ZR, Deane KHO (2013). Relationships between cognitive status and speech, language and communication impairments in Parkinson's disease: a systematic review. International Congress of Parkinson's Disease and Movement Disorders.
Author URL.
Barnish MS, Horton SMC, Butterfint ZR, Deane KHO (2013). Relationships between cognitive status, speech characteristics and communicative participation in Parkinson's disease. International Congress of Parkinson's Disease and Movement Disorders.
Author URL.
Barnish M (2013). Relationships between cognitive status, speech impairment and communicative participation in Parkinson’s disease. University of East Anglia.
Barnish M (eds)(2013). Relationships between cognitive status, speech impairment and communicative participation in Parkinson’s disease.
2012
Barnish M (2012). Acoustic speech characteristics of British people with Parkinson's disease: preliminary results. Parkinson's UK Research Conference 2012.
Barnish M, Horton S, Butterfint Z, Deane KHO (2012). Relationships between cognitive status and communicative participation in Parkinson's disease: preliminary results. Parkinson's UK Research Conference 2012.
Barnish M, Horton S, Butterfint Z, Deane KHO (2012). Relationships between cognitive status and impairments of spoken communication in Parkinson's disease: a systematic review. Parkinson's UK Research Conference 2012.
Barnish M, Horton S, Butterfint Z, Deane KHO (2012). Relationships between cognitive status and language impairments in Parkinson's disease: a systematic review. Parkinson's UK Research Conference 2012.
Barnish M, Butterfint Z, Horton S, Deane KHO (2012). Relationships between cognitive status and speech characteristics in Parkinson's disease: a systematic review. Parkinson's UK Research Conference 2012.
