University of Exeter Medical School

Professor Louise Allan

Professor Louise Allan

Professor of Geriatric Medicine

 L.Allan@exeter.ac.uk

 01392 72 6025

 South Cloisters 1.39

 

South Cloisters, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK

Overview

Professor Louise Allan moved to the University of Exeter as Professor of Geriatric Medicine in June 2018. She has a specialist interest in the Neurology and Psychiatry of Old Age and is a member of the Centre for Research in Ageing and Cognitive Health (REACH), which is a joint venture between the School of Psychology, the University of Exeter Medical School and PenCLAHRC.

Current research themes focus on falls and physical health care in dementia, the effects of delirium upon cognitive decline, and non-Alzheimer’s dementias including post-stroke dementia and Lewy body disease.

Louise completed undergraduate studies at Oxford University and then did house jobs in Oxford and Whitehaven, after which she moved to Newcastle to complete higher medical training as a Geriatrician. She had an Alzheimer’s Society Fellowship for the completion of her doctoral studies on autonomic dysfunction in dementia and then she became a lecturer at Newcastle University (2007-2008) and subsequently a senior lecturer (2008-2018). Clinically, Louise will be working as a Geriatrician in the memory clinic at the Royal Devon and Exeter Hospital.

Qualifications

  • BA(Oxon)
  • MA (Oxon)
  • BMBCh
  • PhD (Newcastle)
  • MRCP (UK)

Back to top

Research

Research interests

Louise’s research focusses on three themes: Physical health in dementia and Delirium, Vascular Cognitive Impairment and Lewy Body disease.

1.         Physical health in dementia

She has previously published work on the risk factors for falls in people with dementia, and is currently leading an NIHR funded Health Technology Assessment Programme to investigate whether it is possible to design a complex intervention to improve the outcome of fall related injuries in dementia (https://research.ncl.ac.uk/difrid/ ).

During her research into dementia delirium has emerged as a significant theme which needs further investigation. The DECIDE study is examining the role of delirium as a potential cause of and exacerbating factor for dementia in a  prospective study which we are now undertaking with the CFAS II cohort.

2.         Vascular Cognitive Impairment

This work includes the long term follow up of the MRC funded COGFAST cohort, one of the world’s largest and longest running clinicopathological cohort studies of people with cerebrovascular disease. We have reported on the long term incidence and neuropathological features of dementia and depression after stroke, and in particular identified that delayed dementia after stroke is primarily associated with predominantly vascular rather than mixed pathology.

We have also established a Nigerian cohort (COGFAST-Nigeria), which will enable comparisons of Vascular Cognitive Impairment between developed and developing countries, the latter being an increasingly important setting for dementia research due to the expanding and ageing demographics in the developing world.

3.         Lewy Body disease

The investigation of Lewy Body disorders is an important focus of research for the DEMANDS group and we host an NIHR Biomedical Research Unit in Lewy Body disease. She is a co-investigator in the DIAMOND-Lewy study, an NIHR funded programme grant which aims to improve the diagnosis and management of Lewy body disorders including Dementia with Lewy bodies and Parkinson’s disease dementia (https://research.ncl.ac.uk/diamondlewy/).

She has an interest in autonomic dysfunction in dementia, and previous work in the MRC funded Lewy Body Disease cohort study has shown that autonomic dysfunction is a particularly common feature of the Lewy body dementias and an important risk factor for falls.

Research projects

Grants/Funding:

  • Lawson R et al: Defining dELIRIUm and its iMpact in Parkinson’s Disease (DELIRIUM-PD) Supervisor, Parkinson’s UK Research Fellowship, £240,589 (2018-2021)
  • AL Robinson et al: Primary and community care based post diagnostic Dementia care (PriDem) Co-investigator Alzheimer’s Society Programme Grant £457,331.29 (2018-2019).
  • LM Allan et al: Identifying delirium in people with Parkinson’s disease (DETERMINE-PD) Principal Investigator Parkinson’s UK Project £29,926.88 (2017-1018).
  • Michael Sykes et al: NIHR Doctoral Fellowship –Supervisor: Enhancing audit and feedback in acute Trust dementia care. £341,011.78 (2017-2020).
  • LM Allan et al: Is it possible to develop a complex intervention to improve the outcome of fall-related injuries in people with dementia? Principal Investigator NIHR HTA Project 13/78/02 £513,008, (2015-2017).
  • S Richardson, LM Allan, S Parker: DECIDE: Delirium and Cognitive Impact in Dementia, Principal Supervisor, Alzheimer’s Society Research Fellowship, £217,232, (2015-2018).
  • A Thomas et al: 123I-MIBG Scintigraphy Utility as a biomarker for Prodromal DEmentia with Lewy Bodies (SUPErB) Co-investigator Alzheimer’s Research UK, £492,273, awarded 2015.
  • John O'Brien et al: Improving the Diagnosis and Management of Dementias of Lewy Body Type in the NHS (DIAMOND-Lewy) Co-investigator NIHR Programme grant, £1,195,337, (2013-2018).

Back to top

Publications

Journal articles

Wheatley A, Bamford C, Brunskill G, Harrison-Dening K, Allan L, Rait G, Robinson L (In Press). A task-shifted approach to post-diagnostic dementia support: a qualitative study exploring professional views and experiences. BMJ Open
Hamilton C, Frith J, Donaghy P, Barker S, Durcan R, Lawley S, Barnett N, Firbank M, Roberts G, Taylor JP, et al (In Press). Assessment of autonomic symptoms may assist with early identification of mild cognitive impairment with Lewy bodies. International Journal of Geriatric Psychiatry
Hamilton C, Frith J, Donaghy P, Barker S, Durcan R, Lawley S, Barnett N, Firbank M, Roberts G, Taylor J-P, et al (In Press). Blood pressure and heart rate responses to orthostatic challenge and Valsalva manoeuvre in mild cognitive impairment with Lewy bodies. International Journal of Geriatric Psychiatry
Richardson S, Murray J, Davis D, Stephan B, Robinson L, Brayne C, Barnes L, Parker S, Sayer A, Dodds R, et al (In Press). Delirium and delirium severity predict the trajectory of the Hierarchical Assessment of Balance and Mobility (HABAM) in hospitalised older people: findings from the DECIDE Study. Journal of Gerontology Series A: Biological Sciences and Medical Sciences
Allan LM (In Press). Developing an Intervention for Fall-Related Injuries in Dementia (DIFRID): an integrated, mixed-methods approach. BMC Geriatrics
Allan LM (In Press). Diagnosis and management of autonomic dysfunction in dementia syndromes. Current Treatment Options in Neurology
Firbank M, Durcan R, O'Brien J, Allan L, Barker S, Ciafone J, Donaghy P, Hamilton C, Lawley S, Roberts G, et al (In Press). Hippocampal and Insula volume in mild cognitive impairment with Lewy bodies. Parkinsonism and Related Disorders
Richardson S, Lawson R, Davis D, Stephan B, Robinson L, Matthews F, Brayne C, Barnes L, Taylor J-P, Parker S, et al (In Press). Hospitalisation without delirium is not associated with cognitive decline in a population-based sample of older people – results from a nested, longitudinal cohort study. Age and Ageing
Frost R, Walters K, Aw S, Brunskill G, Wilcock J, Robinson L, Knapp M, Harrison-Dening K, Allan L, Manthorpe J, et al (In Press). How effective are models of post-diagnostic dementia care delivered by primary care? a systematic review. British Journal of General Practice
Sykes M, Thomson R, Kolehmainen N, Allan L, Finch T (In Press). Impetus to change: a multi-site qualitative exploration of the national audit of dementia. Implementation Science
Frost R, Rait G, Aw S, Brunskill G, Wilcock J, Robinson L, Knapp M, Hogan N, Harrison Dening K, Allan L, et al (In Press). Implementing post diagnostic dementia care in primary care: a mixed-methods systematic review. Aging and Mental Health
O'Brien J, McKeith I, Thomas A, Bamford C, Vale L, Hill S, Allan L, Finch T, McNally R, Hayes L, et al (In Press). Introduction of a management toolkit for Lewy body dementia: a pilot cluster randomised trial. Movement Disorders
Allan LM (In Press). Is it possible to Develop a complex Intervention to improve the outcome of Fall-Related Injuries in people with Dementia? a mixed methods study to develop and assess the feasibility of the DIFRID intervention. Health Technology Assessment
Frost R, Walters K, Wilcock J, Robinson L, Harrison-Dening K, Knapp M, Allan L, Rait G (In Press). Mapping post-diagnostic dementia care in England: an e-survey. Journal of Integrated Care
Firbank M, O'Brien J, Durcan R, Allan L, Barker S, Ciafone J, Donaghy P, Hamilton C, Lawley S, Lloyd J, et al (In Press). Mild cognitive impairment with Lewy bodies: blood perfusion with arterial spin labelling. Journal of Neurology
Donaghy P, Ciafone J, Durcan R, Hamilton C, Barker S, Lloyd J, Firbank M, Allan L, O'Brien J, Taylor J-P, et al (In Press). Mild cognitive impairment with Lewy bodies: neuropsychiatric supportive symptoms and cognitive profile. Psychological Medicine
Pentecost C, Collins R, Dawson E, Stapley S, Quinn C, Charlwood C, Allan L, Victor C, Clare L (In Press). Navigating the coronavirus pandemic two years on: Experiences of carers of people with dementia from the British IDEAL cohort. International Journal of Care and Caring Abstract.
Ciafone J, Thomas A, Durcan R, Donaghy P, Hamilton C, Lawley S, Roberts G, Colloby S, Firbank M, Allan L, et al (In Press). Neuropsychological Impairments and their cognitive architecture in Mild Cognitive Impairment (MCI) with Lewy Bodies and MCI-Alzheimer’s Disease. Journal of the International Neuropsychological Society
Thomas A, Hamilton C, Barker S, Durcan R, Lawley S, Barnett N, Firbank M, Roberts G, Allan L, O'Brien J, et al (In Press). Olfactory Impairment in Mild Cognitive Impairment with Lewy Bodies and Alzheimer’s Disease. International Psychogeriatrics
Richardson S, Davis D, Stephan B, Barnes L, Robinson L, Brayne C, Taylor JP, Parker S, Allan L (In Press). Recurrent delirium over 12 months predicts dementia: results of the Delirium and Cognitive Impact in Dementia (DECIDE) study. Age and Ageing
Goodwin V, Allan L, Bethel A, Cowley A, Cross J, Day J, Drummond A, Howard M, Morley N, Thompson Coon J, et al (In Press). Rehabilitation to enable recovery from COVID-19: a rapid systematic review. Physiotherapy
Allan LM (In Press). Small Vessel Disease Pathological Changes in Neurodegenerative and Vascular Dementias concomitant with Autonomic Dysfunction. Brain Pathology
Allan L, Corbett A, Valderas Martinez J (In Press). Social prescribing programmes to prevent or delay frailty in community-dwelling older adults. Geriatrics
Surendranathan A, Kane J, Bentley A, Barker S, Taylor J-P, Thomas A, Allan L, McNally R, James P, McKeith I, et al (In Press). The Clinical Diagnosis of Lewy Body Dementia. BJPsych Open
Roberts G, Donaghy P, Lloyd J, Durcan R, Petrides G, Colloby S, Lawley S, Ciafone J, Hamilton C, Firbank M, et al (In Press). The accuracy of dopaminergic imaging as a biomarker for mild cognitive impairment with Lewy bodies. British Journal of Psychiatry
Anderson M, Menon R, Oak K, Allan L (In Press). The use of technology for social interaction by people with dementia: a scoping review. PLOS Digital Health
Hamilton C, Matthews F, Allan L, Barker S, Ciafone J, Donaghy P, Durcan R, FIrbank M, Lawley S, O'Brien J, et al (In Press). Utility of the pareidolia test in mild cognitive impairment with Lewy bodies and Alzheimer’s disease. International Journal of Geriatric Psychiatry
Frost R, Rait G, Wheatley A, Wilcock J, Robinson L, Harrison-Dening K, Allan L, Banerjee S, Manthorpe J, Walters K, et al (In Press). What works in managing complex conditions in older people in primary and community care? a state-of-the-art review. Health and Social Care in the Community
Lord JM, Veenith T, Sullivan J, Sharma-Oates A, Richter AG, Greening NJ, McAuley HJC, Evans RA, Moss P, Moore SC, et al (2024). Accelarated immune ageing is associated with COVID-19 disease severity. Immunity and Ageing, 21(1). Abstract.
Sabatini S, Martyr A, Hunt A, Gamble LD, Matthews FE, Thom JM, Jones RW, Allan L, Knapp M, Victor C, et al (2024). Comorbid health conditions and their impact on social isolation, loneliness, quality of life, and well-being in people with dementia: longitudinal findings from the IDEAL programme. BMC Geriatrics, 24(1). Abstract.
Sabatini S, Turner SG, Morris RG, Opdebeeck C, Thom JM, Hunt A, Allan L, Pentecost C, Clare L (2024). Correlates of felt age in caregivers of people with dementia: findings from the IDEAL study. Frontiers in Psychology, 14
Gerakios F, Yarnall AJ, Bate G, Wright L, Davis D, Stephan BCM, Robinson L, Brayne C, Stebbins G, Taylor J-P, et al (2024). Delirium is more common and associated with worse outcomes in Parkinson's disease compared to older adult controls: results of two prospective longitudinal cohort studies. Age and ageing, 53(3). Abstract.
Sabatini S, Martyr A, Hunt A, Gamble LD, Matthews FE, Thom JM, Jones RW, Allan L, Knapp M, Quinn C, et al (2024). Health conditions in spousal caregivers of people with dementia and their relationships with stress, caregiving experiences, and social networks: longitudinal findings from the IDEAL programme. BMC Geriatrics, 24(1). Abstract.
Fernando R, Thomas AJ, Hamilton CA, Durcan R, Barker S, Ciafone J, Barnett N, Olsen K, Firbank M, Roberts G, et al (2024). Identifying parkinsonism in mild cognitive impairment. J Neurol Sci, 458 Abstract.  Author URL.
Greene L, Barber R, Bingham A, Connors J, Conroy S, Elkhafer K, Fox C, Goodwin V, Gordon A, Hall AJ, et al (2024). Maintaining independence in individuals with dementia at home after a fall: a protocol for the UK pilot cluster randomised controlled trial MAINTAIN. BMJ Open, 14(2). Abstract.  Author URL.
Allan L, O'Connell A, Raghuraman S, Bingham A, Laverick A, Chandler K, Connors J, Jones B, Um J, Morgan-Trimmer S, et al (2023). A rehabilitation intervention to improve recovery after an episode of delirium in adults over 65 years (RecoverED): study protocol for a multi-centre, single-arm feasibility study. Pilot Feasibility Stud, 9(1). Abstract.  Author URL.
O'Leary L, Maine A, Ring N, Reid J, Speirs L, Allan L, Truesdale M, Taggart L (2023). A scoping review of the evidence for the use of screening tools in people with intellectual disabilities with dysphagia. Journal of Applied Research in Intellectual Disabilities, 36(3), 429-447. Abstract.
Donaghy PC, Hamilton C, Durcan R, Lawley S, Barker S, Ciafone J, Barnett N, Olsen K, Firbank M, Roberts G, et al (2023). Clinical symptoms in mild cognitive impairment with Lewy bodies: Frequency, time of onset, and discriminant ability. Eur J Neurol, 30(6), 1585-1593. Abstract.  Author URL.
Zheng B, Vivaldi G, Daines L, Leavy OC, Richardson M, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, et al (2023). Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls. The Lancet Regional Health - Europe, 29 Abstract.
Welch C, Wilson D, Sayer AA, Witham MD, Jackson TA, Rajkumar R, Dhesi J, Lochlainn MN, Aspray T, Dodds R, et al (2023). Development of a UK core dataset for geriatric medicine research: a position statement and results from a Delphi consensus process. BMC Geriatrics, 23(1). Abstract.
Cullinan RJ, Richardson SJ, Yarnall AJ, Burn DJ, Allan LM, Lawson RA (2023). Documentation and diagnosis of delirium in Parkinson's disease. Acta Psychiatr Scand, 147(5), 527-535. Abstract.  Author URL.
Rippon I, Victor CR, Martyr A, Matthews FE, Quinn C, Rusted JM, Jones RW, Collins R, van Horik J, Pentecost C, et al (2023). Dyadic perspectives on loneliness and social isolation among people with dementia and spousal carers: findings from the IDEAL programme. Aging Ment Health, 1-9. Abstract.  Author URL.
Schumacher J, Ray NJ, Hamilton CA, Bergamino M, Donaghy PC, Firbank M, Watson R, Roberts G, Allan L, Barnett N, et al (2023). Free water imaging of the cholinergic system in dementia with Lewy bodies and Alzheimer's disease. Alzheimers Dement, 19(10), 4549-4563. Abstract.  Author URL.
Bamford C, Wilcock J, Brunskill G, Wheatley A, Harrison Dening K, Manthorpe J, Allan L, Banerjee S, Booi L, Griffiths S, et al (2023). Improving primary care based post-diagnostic support for people living with dementia and carers: Developing a complex intervention using the Theory of Change. PLoS One, 18(5). Abstract.  Author URL.
Brightling CE, Evans RA, Singapuri A, Smith N, Wain LV, Evans RA, Chalmers JD, Harris VC, Ho LP, Horsley A, et al (2023). Long COVID research: an update from the PHOSP-COVID Scientific Summit. The Lancet Respiratory Medicine, 11(11), e93-e94.
McAuley HJC, Evans RA, Bolton CE, Brightling CE, Chalmers JD, Docherty AB, Elneima O, Greenhaff PL, Gupta A, Harris VC, et al (2023). Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study. eClinicalMedicine, 57 Abstract.
Griffiths S, Spencer E, Wilcock J, Bamford C, Wheatley A, Brunskill G, D'Andrea F, Walters KR, Lago N, O'Keeffe A, et al (2023). Protocol for the feasibility and implementation study of a model of best practice in primary care led postdiagnostic dementia care: PriDem. BMJ Open, 13(8). Abstract.  Author URL.
Durcan R, Roberts G, Hamilton CA, Donaghy PC, Howe K, Colloby SJ, Allan LM, Firbank M, Lawley S, Petrides GS, et al (2023). Serial Nigrostriatal Dopaminergic Imaging in Mild Cognitive Impairment with Lewy Bodies, Alzheimer Disease, and Age-Matched Controls. Neurology, 101(12), e1196-e1205. Abstract.  Author URL.
Aryankhesal A, Blake J, Wong G, Megson M, Briscoe S, Allan L, Broomfield NM, Eastwood Z, Greene L, Hilton A, et al (2023). Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice. British Journal of General Practice, 74(741).
Blake J, Aryankhesal A, Allan L, Ballard C, Briscoe S, Broomfield N, Green L, Hilton A, van Horik J, Khondoker M, et al (2023). Understanding primary care diagnosis and management of sleep disturbance for people with dementia or mild cognitive impairment: a realist review. The British journal of general practice : the journal of the Royal College of General Practitioners, 73 Abstract.
Gamble LD, Parker S, Quinn C, Bennett HQ, Martyr A, Sabatini S, Pentecost C, Collins R, Dawson E, Hunt A, et al (2022). A Comparison of Well-Being of Carers of People with Dementia and Their Ability to Manage Before and During the COVID-19 Pandemic: Findings from the IDEAL Study. Journal of Alzheimer's Disease, 88(2), 679-692.
Wheatley A, Poole M, Robinson L, PriDem study team (2022). Changes to postdiagnostic dementia support in England and Wales during the COVID-19 pandemic: a qualitative study. BMJ Open, 12(2). Abstract.  Author URL.
Schumacher J, Ray NJ, Hamilton CA, Donaghy PC, Firbank M, Roberts G, Allan L, Durcan R, Barnett N, O'Brien JT, et al (2022). Cholinergic white matter pathways in dementia with Lewy bodies and Alzheimer's disease. Brain, 145(5), 1773-1784. Abstract.  Author URL.
Evans RA, Leavy OC, Richardson M, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Saunders RM, Harris VC, et al (2022). Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study. The Lancet Respiratory Medicine, 10(8), 761-775. Abstract.
Delgado J, Evans PH, Gray DP, Sidaway-Lee K, Allan L, Clare L, Ballard C, Masoli J, Valderas JM, Melzer D, et al (2022). Continuity of GP care for patients with dementia: impact on prescribing and the health of patients. Br J Gen Pract, 72(715), e91-e98. Abstract.  Author URL.
Richardson S, Murray J, Davis D, Stephan BCM, Robinson L, Brayne C, Barnes L, Parker S, Sayer AA, Dodds RM, et al (2022). Delirium and Delirium Severity Predict the Trajectory of the Hierarchical Assessment of Balance and Mobility in Hospitalized Older People: Findings from the DECIDE Study. J Gerontol a Biol Sci Med Sci, 77(3), 531-535. Abstract.  Author URL.
Pentecost C, Collins R, Stapley S, Victor C, Quinn C, Hillman A, Litherland R, Allan L, Clare L (2022). Effects of social restrictions on people with dementia and carers during the pre-vaccine phase of the COVID-19 pandemic: Experiences of IDEAL cohort participants. Health Soc Care Community, 30(6), e4594-e4604. Abstract.  Author URL.
Sykes M, O'Halloran E, Mahon L, McSharry J, Allan L, Thomson R, Finch T, Kolehmainen N (2022). Enhancing national audit through addressing the quality improvement capabilities of feedback recipients: a multi-phase intervention development study. Pilot Feasibility Stud, 8(1). Abstract.  Author URL.
Lawson RA, Richardson SJ, Kershaw D, Davis D, Stephan BCM, Robinson L, Brayne C, Barnes L, Burn DJ, Yarnall AJ, et al (2022). Evaluation of Bedside Tests of Attention and Arousal Assessing Delirium in Parkinson's Disease, Dementia, and Older Adults. J Parkinsons Dis, 12(2), 655-665. Abstract.  Author URL.
Quinn C, Gamble LD, Parker S, Martyr A, Collins R, Victor C, Dawson E, Hunt A, Pentecost C, Allan L, et al (2022). Impact of COVID‐19 on carers of people with dementia in the community: Findings from the British IDEAL cohort. International Journal of Geriatric Psychiatry, 37(5). Abstract.
Sabatini S, Bennett HQ, Martyr A, Collins R, Gamble LD, Matthews FE, Pentecost C, Dawson E, Hunt A, Parker S, et al (2022). Minimal Impact of COVID-19 Pandemic on the Mental Health and Wellbeing of People Living with Dementia: Analysis of Matched Longitudinal Data from the IDEAL Study. Frontiers in Psychiatry, 13
Delgado J, Masoli J, Hase Y, Akinyemi R, Ballard C, Kalaria RN, Allan LM (2022). Trajectories of cognitive change following stroke: stepwise decline towards dementia in the elderly. Brain Commun, 4(3). Abstract.  Author URL.
Greene L, Aryankhesal A, Megson M, Blake J, Wong G, Briscoe S, Hilton A, Killett A, Reeve J, Allan L, et al (2022). Understanding primary care diagnosis and management of sleep disturbance for people with dementia or mild cognitive impairment: a realist review protocol. BMJ Open, 12(11). Abstract.  Author URL.
Roberts G, Durcan R, Donaghy PC, Lawley S, Ciafone J, Hamilton CA, Colloby SJ, Firbank MJ, Allan L, Barnett N, et al (2021). Accuracy of Cardiac Innervation Scintigraphy for Mild Cognitive Impairment with Lewy Bodies. Neurology, 96(23), e2801-e2811. Abstract.  Author URL.
Luscombe N, Morgan-Trimmer S, Savage S, Allan L (2021). Digital technologies to support people living with dementia in the care home setting to engage in meaningful occupations: protocol for a scoping review. Syst Rev, 10(1). Abstract.  Author URL.
Schumacher J, Taylor J-P, Hamilton CA, Firbank M, Donaghy PC, Roberts G, Allan L, Durcan R, Barnett N, O'Brien JT, et al (2021). Functional connectivity in mild cognitive impairment with Lewy bodies. J Neurol, 268(12), 4707-4720. Abstract.  Author URL.
Clare L, Martyr A, Gamble LD, Pentecost C, Collins R, Dawson E, Hunt A, Parker S, Allan L, Burns A, et al (2021). Impact of COVID-19 on ‘living well’ with mild-to-moderate dementia in the community: findings from the IDEAL cohort. Journal of Alzheimer’s Disease
O'Brien J, Taylor J-P, Thomas A, Bamford C, Vale L, Hill S, Allan L, Finch T, McNally R, Hayes L, et al (2021). Improving the diagnosis and management of Lewy body dementia: the DIAMOND-Lewy research programme including pilot cluster RCT. Programme Grants for Applied Research, 9(7). Abstract.
Schumacher J, Taylor JP, Hamilton CA, Firbank M, Cromarty RA, Donaghy PC, Roberts G, Allan L, Lloyd J, Durcan R, et al (2021). In vivo nucleus basalis of Meynert degeneration in mild cognitive impairment with Lewy bodies. NeuroImage: Clinical, 30 Abstract.
Bamford C, Wheatley A, Brunskill G, Booi L, Allan L, Banerjee S, Harrison Dening K, Manthorpe J, Robinson L, PriDem study team, et al (2021). Key components of post-diagnostic support for people with dementia and their carers: a qualitative study. PloS one, 16(12). Abstract.
Sykes M, Thomson R, Kolehmainen N, Allan L, Finch T (2021). Opportunities to enhance ward audit: a multi-site qualitative study. BMC Health Serv Res, 21(1). Abstract.  Author URL.
Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB, Lone NI, Leavy OC, et al (2021). Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study. Lancet Respir Med, 9(11), 1275-1287. Abstract.  Author URL.
Delgado J, Jones L, Bradley MC, Allan LM, Ballard C, Clare L, Fortinsky RH, Hughes CM, Melzer D (2021). Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes. Age Ageing, 50(2), 457-464. Abstract.  Author URL.
Hamilton C, Schumacher J, Matthews F, Taylor J-P, Allan L, Barnett N, Cromarty R, Donaghy P, Durcan R, Firbank M, et al (2021). Slowing on quantitative EEG is associated with transition to dementia in mild cognitive impairment. International Psychogeriatrics
Frost R, Walters K, Aw S, Brunskill G, Wilcock J, Robinson L, Knapp M, Dening KH, Allan L, Manthorpe J, et al (2020). Effectiveness of different post-diagnostic dementia care models delivered by primary care: a systematic review. Br J Gen Pract, 70(695), e434-e441. Abstract.  Author URL.
Lawson RA, Richardson SJ, Yarnall AJ, Burn DJ, Allan LM (2020). Identifying delirium in Parkinson disease: a pilot study. International Journal of Geriatric Psychiatry, 35(5), 547-552. Abstract.
O’Rourke G, Parker D, Anderson R, Morgan-Trimmer S, Allan L (2020). Interventions to support recovery following an episode of delirium: a realist synthesis. Aging & Mental Health, 25(10), 1769-1785.
Taylor J-P, McKeith IG, Burn DJ, Boeve BF, Weintraub D, Bamford C, Allan LM, Thomas AJ, O'Brien JT (2020). New evidence on the management of Lewy body dementia. Lancet Neurol, 19(2), 157-169. Abstract.  Author URL.
Bawab N, Moullin JC, Bugnon O, Perraudin C, Morrow A, Chan P, Hogden E, Taylor N, Pearson M, Carrieri D, et al (2020). Proceedings of the Virtual 3rd UK Implementation Science Research Conference. Implementation Science, 15(S4).
Schumacher J, Taylor J-P, Hamilton CA, Firbank M, Cromarty RA, Donaghy PC, Roberts G, Allan L, Lloyd J, Durcan R, et al (2020). Quantitative EEG as a biomarker in mild cognitive impairment with Lewy bodies. Abstract.
Schumacher J, Taylor JP, Hamilton CA, Firbank M, Cromarty RA, Donaghy PC, Roberts G, Allan L, Lloyd J, Durcan R, et al (2020). Quantitative EEG as a biomarker in mild cognitive impairment with Lewy bodies. Alzheimer's Research and Therapy, 12(1). Abstract.
Allan LM, Wheatley A, Smith A, Flynn E, Homer T, Robalino S, Beyer FR, Fox C, Howel D, Barber R, et al (2019). An intervention to improve outcomes of falls in dementia: the DIFRID mixed-methods feasibility study. Health Technol Assess, 23(59), 1-208. Abstract.  Author URL.
Hase Y, Polvikoski TM, Ihara M, Hase M, Zafar R, Stevenson W, Allan LM, Ennaceur A, Horsburgh K, Gallart-Palau X, et al (2019). Carotid artery disease in post-stroke survivors and effects of enriched environment on stroke pathology in a mouse model of carotid artery stenosis. Neuropathol Appl Neurobiol, 45(7), 681-697. Abstract.  Author URL.
Bamford C, Wheatley A, Shaw C, Allan LM (2019). Equipping staff with the skills to maximise recovery of people with dementia after an injurious fall. Aging Ment Health, 23(11), 1524-1532. Abstract.  Author URL.
Allan LM (2019). New evidence on the management of Lewy body dementia. Lancet Neurology
Parker SG, Corner L, Laing K, Nestor G, Craig D, Collerton J, Frith J, Roberts HC, Sayer AA, Allan LM, et al (2019). Priorities for research in multiple conditions in later life (multi-morbidity): findings from a James Lind Alliance Priority Setting Partnership. Age Ageing, 48(3), 401-406. Abstract.  Author URL.
Wheatley A, Bamford C, Shaw C, Boyles M, Fox C, Allan L (2019). Service organisation for people with dementia after an injurious fall: challenges and opportunities. Age Ageing, 48(3), 454-458. Abstract.  Author URL.
Kane JPM, Surendranathan A, Bentley A, Barker SAH, Taylor J-P, Thomas AJ, Allan LM, McNally RJ, James PW, McKeith IG, et al (2018). Clinical prevalence of Lewy body dementia. ALZHEIMERS RESEARCH & THERAPY, 10  Author URL.
Robalino S, Nyakang'o SB, Beyer FR, Fox C, Allan LM (2018). Effectiveness of interventions aimed at improving physical and psychological outcomes of fall-related injuries in people with dementia: a narrative systematic review. Syst Rev, 7(1). Abstract.  Author URL.
Allan LM, Wheatley A, Flynn E, Smith A, Fox C, Howel D, Barber R, Homer TM, Robinson L, Parry SW, et al (2018). Is it feasible to deliver a complex intervention to improve the outcome of falls in people with dementia? a protocol for the DIFRID feasibility study. Pilot Feasibility Stud, 4 Abstract.  Author URL.
Goodwin V, Allan L (2018). Mrs Smith has no rehab potential”: Does rehabilitation have a role in the management of people with dementia. Age and Ageing
Connors MH, Quinto L, McKeith I, Brodaty H, Allan L, Bamford C, Thomas A, Taylor J-P, O'Brien JT (2018). Non-pharmacological interventions for Lewy body dementia: a systematic review. Psychol Med, 48(11), 1749-1758. Abstract.  Author URL.
Skrobot OA, Black SE, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, O'Brien J, Pantoni L, Pasquier F, et al (2018). Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study. ALZHEIMERS & DEMENTIA, 14(3), 280-292.  Author URL.
Thomas AJ, Taylor JP, McKeith I, Bamford C, Burn D, Allan L, O'Brien J (2018). Revision of assessment toolkits for improving the diagnosis of Lewy body dementia: the DIAMOND Lewy study. Int J Geriatr Psychiatry, 33(10), 1293-1304.  Author URL.
Barnfield S, Pitts AC, Kalaria R, Allan L, Tullo E (2017). "Is all the stuff about neurons necessary?" the development of lay summaries to disseminate findings from the Newcastle Cognitive Function after Stroke (COGFAST) study. Res Involv Engagem, 3 Abstract.  Author URL.
Thomas AJ, Taylor JP, McKeith I, Bamford C, Burn D, Allan L, O'Brien J (2017). Development of assessment toolkits for improving the diagnosis of the Lewy body dementias: feasibility study within the DIAMOND Lewy study. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 32(12), 1280-1304.  Author URL.
Akinyemi RO, Allan LM, Oakley A, Kalaria RN (2017). Hippocampal Neurodegenerative Pathology in Post-stroke Dementia Compared to Other Dementias and Aging Controls. FRONTIERS IN NEUROSCIENCE, 11  Author URL.
Richardson SJ, Davis DHJ, Stephan B, Robinson L, Brayne C, Barnes L, Parker S, Allan LM (2017). Protocol for the Delirium and Cognitive Impact in Dementia (DECIDE) study: a nested prospective longitudinal cohort study. BMC GERIATRICS, 17  Author URL.
Sachdev PS, Lo JW, Crawford JD, Mellon L, Hickey A, Williams D, Bordet R, Mendyk A-M, Gelé P, Deplanque D, et al (2017). STROKOG (stroke and cognition consortium): an international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease. Alzheimers Dement (Amst), 7, 11-23. Abstract.  Author URL.
Skrobot OA, O'Brien J, Black S, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, Pantoni L, Pasquier F, et al (2017). The Vascular Impairment of Cognition Classification Consensus Study. ALZHEIMERS & DEMENTIA, 13(6), 624-633.  Author URL.
Harrison SL, Tang EYH, Keage HAD, Taylor J-P, Allan L, Robinson L, Jagger C, Rockwood K, Stephan BCM (2016). A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 42(1-2), 69-79.  Author URL.
Kane JPM, Richardson S, Allan L, Thomas A (2016). Diagnosing dementia. BRITISH JOURNAL OF HOSPITAL MEDICINE, 77(2), C22-C25.  Author URL.
Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung'u MN, Foster V, Craggs LJL, Washida K, Okamoto Y, Thomas AJ, et al (2016). Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia. BRAIN, 139, 242-258.  Author URL.
Dichgans M, Wardlaw J, Smith E, Zietemann V, Seshadri S, Sachdev P, Biessels GJ, Fazekas F, Benavente O, Pantoni L, et al (2016). METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: an initiative of the Joint Programme for Neurodegenerative Disease Research. ALZHEIMERS & DEMENTIA, 12(12), 1235-1249.  Author URL.
Chen A, Oakley AE, Monteiro M, Tuomela K, Allan LM, Mukaetova-Ladinska EB, O'Brien JT, Kalaria RN (2016). Multiplex analyte assays to characterize different dementias: brain inflammatory cytokines in poststroke and other dementias. NEUROBIOLOGY OF AGING, 38, 56-67.  Author URL.
Akinyemi RO, Firbank M, Ogbole GI, Allan LM, Owolabi MO, Akinyemi JO, Yusuf BP, Ogunseyinde O, Ogunniyi A, Kalaria RN, et al (2015). Medial temporal lobe atrophy, white matter hyperintensities and cognitive impairment among Nigerian African stroke survivors. BMC Res Notes, 8 Abstract.  Author URL.
Tullo ES, Lee RP, Robinson L, Allan L (2015). Why is dementia different? Medical students' views about deceiving people with dementia. AGING & MENTAL HEALTH, 19(8), 731-738.  Author URL.
Mayne DJF, Allan L, Reynish E, MacLullich AMJ, Vardy ERLC (2014). Experience and opinions on post-graduate dementia training in the UK: a survey of selected consultant geriatricians. AGE AND AGEING, 43(2), 263-266.  Author URL.
Gemmell E, Tam E, Allan L, Hall R, Khundakar A, Oakley AE, Thomas A, Deramecourt V, Kalaria RN (2014). Neuron Volumes in Hippocampal Subfields in Delayed Poststroke and Aging-Related Dementias. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 73(4), 305-311.  Author URL.
Akinyemi RO, Allan L, Owolabi MO, Akinyemi JO, Ogbole G, Ajani A, Firbank M, Ogunniyi A, Kalaria RN (2014). Profile and determinants of vascular cognitive impairment in African stroke survivors: the CogFAST Nigeria Study. JOURNAL OF THE NEUROLOGICAL SCIENCES, 346(1-2), 241-249.  Author URL.
Foster V, Oakley AE, Slade JY, Hall R, Polvikoski TM, Burke M, Thomas AJ, Khundakar A, Allan LM, Kalaria RN, et al (2014). Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias. BRAIN, 137, 2509-2521.  Author URL.
Kuhn E, Du X, McGrath K, Coveney S, O'Regan N, Richardson S, Teodorczuk A, Allan L, Wilson D, Inouye SK, et al (2014). Validation of a Consensus Method for Identifying Delirium from Hospital Records. PLOS ONE, 9(11).  Author URL.
Allan LM, Rowan EN, Thomas AJ, Polvikoski TM, O'Brien JT, Kalaria RN (2013). Long-term incidence of depression and predictors of depressive symptoms in older stroke survivors. BRITISH JOURNAL OF PSYCHIATRY, 203(6), 453-460.  Author URL.
Gemmell E, Bosomworth H, Allan L, Hall R, Khundakar A, Oakley AE, Deramecourt V, Polvikoski TM, O'Brien JT, Kalaria RN, et al (2012). Hippocampal Neuronal Atrophy and Cognitive Function in Delayed Poststroke and Aging-Related Dementias. STROKE, 43(3), 808-+.  Author URL.
Firbank MJ, Allan LM, Burton EJ, Barber R, O'Brien JT, Kalaria RN (2012). Neuroimaging predictors of death and dementia in a cohort of older stroke survivors. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 83(3), 263-267.  Author URL.
Allan LM, Rowan EN, Firbank MJ, Thomas AJ, Parry SW, Polvikoski TM, O'Brien JT, Kalaria RN (2011). Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors. BRAIN, 134, 3713-3724.  Author URL.
Morris CM, Ballard CG, Allan L, Rowan E, Stephens S, Firbank M, Ford GA, Kenny RA, O'Brien JT, Kalaria RN, et al (2011). NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors. Neurobiology of Aging, 32(3), 554.e1-554.e6. Abstract.
Tullo E, Allan L (2011). What should we be teaching medical students about dementia?. INTERNATIONAL PSYCHOGERIATRICS, 23(7), 1044-1050.  Author URL.
Tullo ES, Spencer J, Allan L (2010). Systematic Review: Helping the Young to Understand the Old. Teaching Interventions in Geriatrics to Improve the Knowledge, Skills, and Attitudes of Undergraduate Medical Students. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 58(10), 1987-1993.  Author URL.
Miller VM, Kenny RA, Oakley AE, Hall R, Kalaria RN, Allan LM (2009). Dorsal Motor Nucleus of Vagus protein aggregates in Lewy Body Disease with autonomic dysfunction. BRAIN RESEARCH, 1286, 165-173.  Author URL.
Allan LM, Ballard CG, Rowan EN, Kenny RA (2009). Incidence and prediction of falls in dementia: a prospective study in older people. PLoS ONE, 4(5). Abstract.
Allan LM, Ballard CG, Allen J, Murray A, Davidson AW, McKeith IG, Kenny RA (2007). Autonomic dysfunction in dementia. J Neurol Neurosurg Psychiatry, 78(7), 671-677. Abstract.  Author URL.
McKeith IG, Rowan E, Askew K, Naidu A, Allan L, Barnett N, Lett D, Mosimann UP, Burn D, O'Brien JT, et al (2006). More severe functional impairment in dementia with Lewy bodies than Alzheimer disease is related to extrapyramidal motor dysfunction. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 14(7), 582-588.  Author URL.
Burn DJ, Rowan EN, Allan LM, Molloy S, T O'Brien J, McKeith IG (2006). Motor subtype and cognitive decline in Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bodies. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 77(5), 585-589.  Author URL.
Allan L, McKeith I, Ballard C, Kenny RA (2006). The prevalence of autonomic symptoms in dementia and their association with physical activity, activities of daily living and quality of life. Dementia and Geriatric Cognitive Disorders, 22(3), 230-237. Abstract.
Allan LM, Kerr SRJ, Ballard CG, Allen J, Murray A, McLaren AT, Kenny RA (2005). Autonomic function assessed by heart rate variability is normal in Alzheimer's disease and vascular dementia. Dement Geriatr Cogn Disord, 19(2-3), 140-144. Abstract.  Author URL.
McLaren A, Kerr S, Allan L, Steen IN, Ballard C, Allen J, Murray A, Kenny RA (2005). Autonomic function is impaired in elderly stroke survivors. Stroke, 36(5), 1026-1030. Abstract.  Author URL.
Allan LM, Ballard CG, Burn DJ, Kenny RA (2005). Prevalence and severity of gait disorders in Alzheimer's and non-Alzheimer's dementias. Journal of the American Geriatrics Society, 53(10), 1681-1687. Abstract.
Allan L, Johns E, Doshi M, Kenny RA, Newton JL (2004). Abnormalities of sympathetic and parasympathetic autonomic function in subjects with defaecation syncope. EUROPACE, 6(3), 192-198.  Author URL.
Stephens S, Kenny RA, Rowan E, Allan L, Kalaria RN, Bradbury M, Ballard CG (2004). Neuropsychological characteristics of mild vascular cognitive impairment and dementia after stroke. International Journal of Geriatric Psychiatry, 19(11), 1053-1057. Abstract.
Newton JL, Allan L, Baptist M, Kenny R (2001). Defecation syncope associated with splanchnic sympathetic dysfunction and cured by permanent pacemaker insertion. AMERICAN JOURNAL OF GASTROENTEROLOGY, 96(7), 2276-2278.  Author URL.
Williams JH, Wellman NA, Allan LM, Taylor E, Tonin J, Feldon J, Rawlins JNP (1996). Tobacco smoking correlates with schizotypal and borderline personality traits. PERSONALITY AND INDIVIDUAL DIFFERENCES, 20(2), 267-270.  Author URL.
ALLAN LM, WILLIAMS JH, WELLMAN NA, TONIN J, TAYLOR E, FELDON J, RAWLINS JNP (1995). EFFECTS OF TOBACCO SMOKING, SCHIZOTYPY AND NUMBER OF PRE-EXPOSURES ON LATENT INHIBITION IN HEALTHY-SUBJECTS. PERSONALITY AND INDIVIDUAL DIFFERENCES, 19(6), 893-902.  Author URL.

Chapters

Kenny RA, Allan LM (2005). Autonomic dysfunction in dementia with lewy bodies. In  (Ed) Dementia with Lewy Bodies: and Parkinson's Disease Dementia, 107-128. Abstract.

Conferences

Delgado J, Sidaway-Lee K, Evans P, Gray DP, Clare L, Allan L, Valderas JM, Masoli JA, Melzer D (2021). Continuity of care and prescribing safety in the treatment of dementia.  Author URL.
Sykes M, Thomson R, Kolehmainen N, Allan L, Finch T (2020). A co-designed intervention to enhance the national audit of dementia.  Author URL.
Cullinan R, Richardson S, Yarnall A, Burn D, Allan L, Lawson R (2020). Identification and Documentation of Delirium in Parkinson's Disease.  Author URL.
Hase Y, Polvikoski T, Hase M, Stevenson W, Ihara M, Allan L, Horsburgh K, Kalaria R (2019). Carotid artery disease, strokes and experimental effects of enriched environment on stroke injury.  Author URL.
Ballard C, Allan L, Corbett A, Creese B, Brooker H, Fox C, Sami S, Shepstone L, Khondoker M, Richardson K, et al (2019). Interaction of Biological and Psychosocial Factors in Dementia.  Author URL.
Robalino S, Nyakang'o SB, Beyer F, Fox C, Allan LM (2018). EFFECTIVENESS OF INTERVENTIONS AIMED AT IMPROVING PHYSICAL AND PSYCHOLOGICAL OUTCOMES OF FALL-RELATED INJURIES IN PEOPLE WITH DEMENTIA: a SYSTEMATIC REVIEW.  Author URL.
Richardson S, Davis D, Stephan B, Robinson L, Brayne C, Barnes L, Parker S, Allan L (2018). PERCEPTUAL DISTURBANCES IN a POPULATION OF OLDER PEOPLE IN HOSPITAL: INCIDENCE, CONTENT AND ASSOCIATION WITH DELIRIUM.  Author URL.
McCormack V, Allan L, Davis D, Richardson S, Steffan B (2017). WHAT IS THE EFFECT OF DELIRIUM UPON THE TRAJECTORY OF COGNITIVE DECLINE IN THE LEWY BODY DISORDERS? a RETROSPECTIVE EXAMINATION OF EPISODES OF DELIRIUM IN a LONGITUDINAL COHORT OF PEOPLE WITH PARKINSON'S DISEASE (PD), PARKINSON'S DISEASE DEMENTIA (PDD) AND DEMENTIA WITH LEWY BODIES (DLB).  Author URL.
Chen A, Akinyemi RO, Washida K, Foster V, Firbank MJ, Oakley AE, Okamoto Y, O'Brien JT, Allan LM, Ihara M, et al (2015). Frontal white matter clasmatodendrosis and cognitive dysfunction in the elderly.  Author URL.
Akinyemi RO, Allan L, Ogunniyi A, Kalaria RN (2014). Profile and determinants associated with vascular cognitive impairment in African stroke survivors: the CogFAST - Nigeria study.  Author URL.
Kuhn E, O'Regan N, McGrath K, Coveney S, Du XY, Teodorczuk A, Allan L, Wilson D, MacLullich A, Meagher D, et al (2013). Consensus Validation of a Method for Delirium Identification Using Hospital Records.  Author URL.
Allan LM, Ballard CG, Allen J, Murray A, Davidson A, Kenny R (2005). Autonomic dysfunction is present in dementia with Lewy bodies.  Author URL.
Allan LM, Ballard CG, Davidson A, Kenny R (2005). Prevalence of orthostatic hypotension in common dementia disorders.  Author URL.
Allan LM, Burn DJ, Ballard CG, Kenny R (2004). Early presentation of gait disorder is indicative of non-Alzheimer's dementia.  Author URL.
Mosimann UP, Felblinger J, Müri RM, Allan L, Pakrasi S, Bowman LC, O'Brien JT (2003). Saccadic eye movements in dementia with Lewy bodies.  Author URL.
Allan L, Johns CE, Doshi M, Newton JL (2002). Defecation syncope is associated with abnormalities of sympathetic and parasympathetic autonomic nervous function.  Author URL.

Back to top

External Engagement and Impact

Awards

  • 2008   Clinical Senior Lecturer Award (Hefce/UKCRN)
  • 2001   Clinical Research Fellowship, Alzheimer’s Society, UK
  • 1991   Martin Wronker prize for Medicine

(awarded for the highest 1st class honours degree in Physiological Sciences, Oxford University)


Committee/panel activities

  • 2009-present Dementia lead, Dementia and Related Disorders Section, British Geriatrics Society
  • 2015-present Right Care Task Force member, National Dementia Action Alliance (a taskforce of senior policymakers and clinicians coordinating the Dementia Friendly Hospitals campaign)
  • 2015-2018 Committee member, NICE Guideline Development Committee for Dementia

Invited lectures

  • Dementia: A tale of Anticholinergic burden. UK Continence Society Conference 2017

Back to top

Edit Profile