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Dr Katie Young

Dr Katie Young

Postdoctoral Research Associate

 

Overview

Katie is a Postdoctoral Research Associate in Health Data Science, working in Professor Andrew Hattersley’s diabetes research team.

Previously Katie worked as a Research Data Coordinator within the team, working with the data from UK Biobank (particularly primary care records) to identify prevalent and incident cases of diabetes.

In her current role she is working with Dr John Dennis on stratified medicine in Type 2 diabetes, using primary care data from the Clinical Practice Research Datalink (CPRD).

Qualifications

  • PhD in Biophysics (University of Oxford)
  • MBiochem Biochemistry (University of Oxford)

Research

Research interests

  • Primary care record usage in research
  • Type 2 diabetes
  • Stratified / personalised medicine

Publications

Key publications | Publications by category | Publications by year

Key publications


Dennis JM, Young KG, McGovern AP, Mateen BA, Vollmer SJ, Simpson MD, Henley WE, Holman RR, Sattar N, Pearson ER, et al (In Press). Derivation and validation of a type 2 diabetes treatment selection algorithm for SGLT2-inhibitor and DPP4-inhibitor therapies based on glucose-lowering efficacy: cohort study using trial and routine clinical data.  Abstract.
Young KG, McDonald TJ, Shields BM (In Press). Glycated haemoglobin measurements from UK Biobank are different to those in linked primary care records: implications for combining biochemistry data from research studies and routine clinical care.  Abstract.  Full text.
Hagenaars SP, Gillett AC, Casanova F, Young KG, Green H, Lewis CM, Tyrrell J (In Press). The impact of depression diagnosis on diabetes and lifetime hyperglycaemia.  Abstract.
Green HD, Young KG, Jones AG, Weedon MN, Dennis JM (In Press). Using joint models to adjust for informative drop-out when modelling a longitudinal biomarker: an application to type 2 diabetes disease progression.  Abstract.
Heald AH, Martin S, Fachim H, Green HD, Young KG, Malipatil N, Siddals K, Cortes G, Tyrrell J, Wood AR, et al (2021). Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile. Diabetic Medicine, 38(9). Full text.
Young KG, Dennis JM, Thomas NJ, Jones AG, McGovern A, Shields BM, Barroso I, Hattersley AT (2021). Participants with undiagnosed diabetes in UK Biobank wait on average two years to receive a diagnosis, and simple clinical features are associated with diagnosis delays.  Author URL.

Publications by category


Journal articles

Young KG, McDonald TJ, Shields BM (In Press). Glycated haemoglobin measurements from UK Biobank are different to those in linked primary care records: implications for combining biochemistry data from research studies and routine clinical care.  Abstract.  Full text.
(2022). Oral abstracts. Diabetic Medicine, 39(S1).
Heald AH, Martin S, Fachim H, Green HD, Young KG, Malipatil N, Siddals K, Cortes G, Tyrrell J, Wood AR, et al (2021). Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile. Diabetic Medicine, 38(9). Full text.
Young KG, Najafi B, Sant WM, Contera S, Louis AA, Doye JPK, Turberfield AJ, Bath J (2020). Reconfigurable T‐junction DNA Origami. Angewandte Chemie, 132(37), 16076-16080.

Conferences

Young KG, Hopkins R, Thomas NJ, Shields BM, Dennis JM, McGovern AP (2022). Current rates of sodium-glucose link transporter 2 inhibitors (SGLT2i) prescribing in type 2 diabetes show no evidence of prioritisation in those with cardiovascular disease and heart failure.  Author URL.
Hopkins R, Godwin J, Young KG, Mateen BA, Vollmer SJ, Thomas NJ, Shields BM, McGovern AP, Dennis JM (2022). In people with type 2 diabetes most risk factors for covid-19 mortality are shared with pneumonia, however ethnicity related risk is very different.  Author URL.
Gilchrist M, Casanova F, Tyrrell J, Fife N, Young K, Oram R, Weedon M (2021). MO042PREVALENCE OF FABRY DISEASE CAUSING VARIANTS IN THE UK BIOBANK.  Abstract.
Young KG, Dennis JM, Thomas NJ, Jones AG, McGovern A, Shields BM, Barroso I, Hattersley AT (2021). Participants with undiagnosed diabetes in UK Biobank wait on average two years to receive a diagnosis, and simple clinical features are associated with diagnosis delays.  Author URL.
Carr ALJ, Sharp SA, Young KG, Thomas NJ, Hattersley AT, Jones AG, Oram RA (2020). A type 1 diabetes genetic risk score is discriminative of adult-onset type 1 diabetes.  Author URL.
Young KG, Hill A, Tippett P, Knight BA, Hattersley AT, McDonald T, Shields BM, Thomas NJ, Jones AG, Grp SS, et al (2020). Adult-onset autoimmune diabetes has similar markers of severity and progression regardless of age of diagnosis, but is less likely to be managed intensively when diagnosed in older adults.  Author URL.
Young KG, Thomas NJ, Jones AG, McGovern A, Shields BM, Barroso I, Hattersley AT (2020). HbA(1c) screening in 195,460 'non-diabetic' individuals (40-69 years) identifies 1.1% with undiagnosed diabetes 2 years before clinical diagnosis.  Author URL.
Young K, Najafi B, Bath J, Turberfield A (2017). DNA T-junctions for studies of DNA origami assembly.

Publications by year


In Press

Dennis JM, Young KG, McGovern AP, Mateen BA, Vollmer SJ, Simpson MD, Henley WE, Holman RR, Sattar N, Pearson ER, et al (In Press). Derivation and validation of a type 2 diabetes treatment selection algorithm for SGLT2-inhibitor and DPP4-inhibitor therapies based on glucose-lowering efficacy: cohort study using trial and routine clinical data.  Abstract.
Young KG, McDonald TJ, Shields BM (In Press). Glycated haemoglobin measurements from UK Biobank are different to those in linked primary care records: implications for combining biochemistry data from research studies and routine clinical care.  Abstract.  Full text.
Thomas NJ, McGovern A, Young KG, Sharp SA, Weedon MN, Hattersley AT, Dennis J, Jones AG (In Press). Identifying type 1 and 2 diabetes in population level data: assessing the accuracy of published approaches.  Abstract.
Hagenaars SP, Gillett AC, Casanova F, Young KG, Green H, Lewis CM, Tyrrell J (In Press). The impact of depression diagnosis on diabetes and lifetime hyperglycaemia.  Abstract.
Green HD, Young KG, Jones AG, Weedon MN, Dennis JM (In Press). Using joint models to adjust for informative drop-out when modelling a longitudinal biomarker: an application to type 2 diabetes disease progression.  Abstract.

2022

Young KG, Hopkins R, Thomas NJ, Shields BM, Dennis JM, McGovern AP (2022). Current rates of sodium-glucose link transporter 2 inhibitors (SGLT2i) prescribing in type 2 diabetes show no evidence of prioritisation in those with cardiovascular disease and heart failure.  Author URL.
Thomas NJ, McGovern A, Young K, Sharp SA, Weedon MN, Hattersley A, Dennis J, Jones AG (2022). Identifying Type 1 and 2 Diabetes in Population Level Data: Assessing the Accuracy of Published Approaches.
Hopkins R, Godwin J, Young KG, Mateen BA, Vollmer SJ, Thomas NJ, Shields BM, McGovern AP, Dennis JM (2022). In people with type 2 diabetes most risk factors for covid-19 mortality are shared with pneumonia, however ethnicity related risk is very different.  Author URL.
(2022). Oral abstracts. Diabetic Medicine, 39(S1).

2021

Heald AH, Martin S, Fachim H, Green HD, Young KG, Malipatil N, Siddals K, Cortes G, Tyrrell J, Wood AR, et al (2021). Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile. Diabetic Medicine, 38(9). Full text.
Gilchrist M, Casanova F, Tyrrell J, Fife N, Young K, Oram R, Weedon M (2021). MO042PREVALENCE OF FABRY DISEASE CAUSING VARIANTS IN THE UK BIOBANK.  Abstract.
Young KG, Dennis JM, Thomas NJ, Jones AG, McGovern A, Shields BM, Barroso I, Hattersley AT (2021). Participants with undiagnosed diabetes in UK Biobank wait on average two years to receive a diagnosis, and simple clinical features are associated with diagnosis delays.  Author URL.

2020

Carr ALJ, Sharp SA, Young KG, Thomas NJ, Hattersley AT, Jones AG, Oram RA (2020). A type 1 diabetes genetic risk score is discriminative of adult-onset type 1 diabetes.  Author URL.
Young KG, Hill A, Tippett P, Knight BA, Hattersley AT, McDonald T, Shields BM, Thomas NJ, Jones AG, Grp SS, et al (2020). Adult-onset autoimmune diabetes has similar markers of severity and progression regardless of age of diagnosis, but is less likely to be managed intensively when diagnosed in older adults.  Author URL.
Najafi B, Young KG, Bath J, Louis AA, Doye JPK, Turberfield AJ (2020). Characterising DNA T-motifs by Simulation and Experiment. Arxiv Abstract.
Young KG, Thomas NJ, Jones AG, McGovern A, Shields BM, Barroso I, Hattersley AT (2020). HbA(1c) screening in 195,460 'non-diabetic' individuals (40-69 years) identifies 1.1% with undiagnosed diabetes 2 years before clinical diagnosis.  Author URL.
Young KG, Najafi B, Sant WM, Contera S, Louis AA, Doye JPK, Turberfield AJ, Bath J (2020). Reconfigurable T‐junction DNA Origami. Angewandte Chemie, 132(37), 16076-16080.

2017

Young K, Najafi B, Bath J, Turberfield A (2017). DNA T-junctions for studies of DNA origami assembly.

Katie_Young Details from cache as at 2022-07-03 23:55:30

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