Josh Harvey | The Medical School | University of Exeter

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University of Exeter Medical School

Josh Harvey

Postdoctoral Research Associate

j.d.harvey@exeter.ac.uk

07854463002

RILD Building Level 4

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Overview

Josh is a postdoctoral research associate in the Dementia Genomics team in the Complex Disease Epigenetics group. His research focusses on investigating gene regulatory and epigenomic changes in neurodegenerative diseases, with particular interest in DNA methylation and spatial molecular profiling methods. Currently his primary project looks to explore gene expression and microRNA changes in the brains of patients with familial Alzheimer's disease.

In 2019 Josh joined the Epigenetics of Complex Diseases group at the RILD as a PhD Student under the supervision of Professor Katie Lunnon, Dr. Ehsan Pishva and Professor Jon Mill. His PhD project will focussed on profiling epigenomic changes in methylation state associated with Dementia with Lewy bodies and Parkinson’s Disease Dementia. Prior to this , Josh worked for Eli Lilly and Co. as a neuropathologist researching neurodegenerative conditions through histological analysis of mouse and human samples.

Qualifications

First Author Publications:
Elucidating distinct molecular signatures of Lewy body dementias. Harvey J, Pishva E, Chouliaras L, Lunnon K. Neurobiol Dis. 2023;188:106337. doi:10.1016/j.nbd.2023.106337
Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson's disease: A DNA co-methylation network analysis. Harvey J, Smith AR, Weymouth LS, et al. Epigenetic Preprint. bioRxiv, https://doi.org/10.1101/2023.07.20.549825
Machine learning-based prediction of cognitive outcomes in de novo Parkinson's disease. Harvey J, Reijnders RA, Cavill R, et al. NPJ Parkinsons Dis. 2022;8(1):150. 2022. doi:10.1038/s41531-022-00409-5
Grants/Funding:
Charles Wolfson Charitable Trust
MRC Research Grant (PI Lunnon)

Research

Research interests

Neurodegenerative disease, in particular alpha-synucleinopathies. Epigenetics, Neuropathology, Genomics, Neuroscience.

Research projects

Current Projects:

A role for epigenetic changes in Dementia with Lewy bodies

ResearchGate: https://www.researchgate.net/profile/Joshua_Harvey7

Publications