University of Exeter Medical School

Dr João Pedro Correa Delgado

Dr João Pedro Correa Delgado

Lecturer

 J.Correa-Delgado@exeter.ac.uk

 01392 406761

 College House 

 

College House, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK

Overview

Dr. João Delgado has a background in biological science and epidemiology and a curiosity for knowledge has led me to pursue research. Joao joined the Epidemiology and Public Health group in Exeter in October 2014, where he focuses on producing research that is easily transferable to clinical practice.

Currently, João is studying the management of conditions affecting cognitive function in old age, including dementia and delirium. João is leading the delivery of an NIHR grant on producing risk stratification tools for identifying individuals at risk of delirium living in the community. João is also currently supported by the Alzheimer’s Society, through a Junior Fellowship, to investigate prescribing quality in people living with dementia and how modes of care delivery can improve this. João brings advanced research experience, a wealth of epidemiological knowledge, a highly developed capacity for critical thinking and experience in liaising with government and public stakeholders at national and local levels.

João works collaboratively with colleagues in Exeter and abroad, including charities such as the Alzheimer’s Society and AGE UK and the University of Connecticut.

Qualifications

  • PhD, Epidemiology and Risk Analysis - Cranfield University, United Kingdom
  • Degree in Veterinary medicine – Faculdade de Medicina Veterinária (FMV) de Lisboa

Career

Awards

  • Best submission in the Epidemiology Category – The American Geriatrics Society 2016 Annual Meeting

  • British Geriatrics Society Cardiovascular Section Meeting 2017, 1st Prize poster

Research group links

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Research

Research interests

João’s research interests lie on the management of conditions affecting cognitive function in old age, including dementia and delirium. With specific focus on producing research that leads to improvements quality of life and better health services for older individuals.

João has significant experience using traditional and modern epidemiology and statistical tools to analyse  large datasets of electronical health records (CPRD primary care and linked hospital records). João is curently exploring the use of artificial intelligence and machine learning methods to help improve health care service delievry for older individuals, based on the analysis of electronic health records.

Research projects

  • Alzheimer’s Society - Junior Fellowship Application: Improving treatment of people with dementia and additional health conditions
  • National Institute for Health Research – Research for Patient Benefit: Developing tools for preventing delirium in primary care 
  • NIDUS Junior Investigator Pilot Award - Genetic variation and predisposition to delirium

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Publications

Journal articles

Atkins J, Masoli J, Correa-Delgado J, Pilling L, Kuo C-L, Melzer D, Kuchel G (In Press). PREEXISTING COMORBIDITIES PREDICTING COVID-19 AND MORTALITY IN THE UK BIOBANK COMMUNITY COHORT. Journal of Gerontology Series A: Biological Sciences and Medical Sciences
Zirk-Sadowski J, Masoli J, Strain WD, Delgado J, Henley W, Hamilton W, Melzer D, Ble A (In Press). Proton-Pump Inhibitors and Fragility Fractures in Vulnerable Older Patients. The American Journal of Gastroenterology (Elsevier)
Delgado J, Evans PH, Gray DP, Sidaway-Lee K, Allan L, Clare L, Ballard C, Masoli J, Valderas JM, Melzer D, et al (2022). Continuity of GP care for patients with dementia: impact on prescribing and the health of patients. Br J Gen Pract, 72(715), e91-e98. Abstract.  Author URL.
Delgado J, Masoli J, Hase Y, Akinyemi R, Ballard C, Kalaria RN, Allan LM (2022). Trajectories of cognitive change following stroke: stepwise decline towards dementia in the elderly. Brain Commun, 4(3). Abstract.  Author URL.
Pilling LC, Turkmen D, Fullalove H, Atkins JL, Delgado J, Kuo C-L, Kuchel GA, Ferrucci L, Bowden J, Masoli JAH, et al (2021). Analysis of <i>CYP2C19</i> genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study. BMJ OPEN, 11(12).  Author URL.
Varma VR, Wang Y, an Y, Varma S, Bilgel M, Doshi J, Legido-Quigley C, Delgado JC, Oommen AM, Roberts JA, et al (2021). Bile acid synthesis, modulation, and dementia: a metabolomic, transcriptomic, and pharmacoepidemiologic study. PLoS Med, 18(5). Abstract.  Author URL.
Kuo C-L, Pilling LC, Atkins JL, Masoli JAH, Delgado J, Tignanelli C, Kuchel GA, Melzer D, Beckman KB, Levine ME, et al (2021). Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants. The Journals of Gerontology: Series A, 76(8), e133-e141. Abstract.
Masoli JAH, Delgado J (2021). Blood pressure, frailty and dementia. Experimental Gerontology, 155 Abstract.
Delgado J, Jones L, Bradley MC, Allan LM, Ballard C, Clare L, Fortinsky RH, Hughes CM, Melzer D (2021). Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes. Age Ageing, 50(2), 457-464. Abstract.  Author URL.
Kuo C-L, Pilling LC, Atkins JL, Masoli JAH, Delgado J, Kuchel GA, Melzer D (2020). <i>ApoE</i> e4e4 genotype and mortality with COVID-19 in UK Biobank. Abstract.
Kuo C-L, Pilling LC, Atkins JL, Masoli JAH, Delgado J, Kuchel GA, Melzer D (2020). APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort. J Gerontol a Biol Sci Med Sci, 75(11), 2231-2232.  Author URL.
Kuo C-L, Pilling LC, Atkins JL, Masoli JAH, Delgado J, Kuchel GA, Melzer D (2020). ApoE e4e4 Genotype and Mortality with COVID-19 in UK Biobank. The Journals of Gerontology: Series A, 75(9), 1801-1803.
Masoli JAH, Delgado J, Pilling L, Strain D, Melzer D (2020). Blood pressure in frail older adults: associations with cardiovascular outcomes and all-cause mortality. Age Ageing, 49(5), 807-813. Abstract.  Author URL.
Kuo C-L, Pilling LC, Atkins JL, Masoli JAH, Delgado J, Tignanelli C, Kuchel GA, Melzer D, Beckman KB, Levine ME, et al (2020). COVID-19 severity is predicted by earlier evidence of accelerated aging. Abstract.
Pilling LC, Jones LC, Masoli JAH, Delgado J, Atkins JL, Bowden J, Fortinsky RH, Kuchel GA, Melzer D (2020). Low Vitamin D Levels and Risk of Incident Delirium in 351,000 Older <scp>UK</scp> Biobank Participants. Journal of the American Geriatrics Society, 69(2), 365-372. Abstract.
Delgado J, Bowman K, Clare L (2020). Potentially inappropriate prescribing in dementia: a state-of-the-art review since 2007. BMJ Open, 10(1). Abstract.  Author URL.
Bowman K, Jones L, Masoli J, Mujica-Mota R, Strain D, Butchart J, Valderas JM, Fortinsky RH, Melzer D, Delgado J, et al (2020). Predicting incident delirium diagnoses using data from primary-care electronic health records. Age Ageing, 49(3), 374-381. Abstract.  Author URL.
Atkins JL, Masoli JAH, Delgado J, Pilling LC, Kuo C-L, Kuchel GA, Melzer D (2020). Preexisting Comorbidities Predicting Severe Covid-19 in Older Adults in the UK Biobank Community Cohort. Abstract.
Masoli J, Correa Delgado J, Bowman K, Strain W, Henley W, Melzer D (2019). Association of blood pressure with clinical outcomes in older adults with chronic kidney disease. Age and Ageing
Atkins JL, Delgado J, Melzer D (2019). Life’s Simple 7 likely to be associated with dementia risk reduction in both midlife and older age groups. BMJ, l5491-l5491.
Komajda M, Schöpe J, Wagenpfeil S, Tavazzi L, Böhm M, Ponikowski P, Anker SD, Filippatos GS, Cowie MR, Aleksanyan A, et al (2019). Physicians' guideline adherence is associated with long-term heart failure mortality in outpatients with heart failure with reduced ejection fraction: the QUALIFY international registry. European Journal of Heart Failure, 21(7), 921-929. Abstract.
Bowman K, Jones L, Pilling LC, Delgado J, Kuchel GA, Ferrucci L, Fortinsky RH, Melzer D (2019). Vitamin D levels and risk of delirium: a mendelian randomization study in the UK Biobank. Neurology
Delgado J, Bowman K, Ble A, Masoli J, Han Y, Henley W, Welsh S, Kuchel GA, Ferrucci L, Melzer D, et al (2018). Blood Pressure Trajectories in the 20 Years Before Death. JAMA Intern Med, 178(1), 93-99. Abstract.  Author URL.
Atkins JL, Delgado J, Pilling L, Bowman K, Masoli J, Kuchel G, Ferrucci L, Melzer D (2018). Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence from 421,000 Participants in Two Cohorts. Journals of Gerontology: Medical Sciences
Zirk-Sadowski J, Masoli JA, Delgado J, Hamilton W, Strain WD, Henley W, Melzer D, Ble A (2018). Proton-Pump Inhibitors and Long-Term Risk of Community-Acquired Pneumonia in Older Adults. J Am Geriatr Soc, 66(7), 1332-1338. Abstract.  Author URL.
Bowman K, Atkins JL, Delgado J, Kos K, Kuchel GA, Ble A, Ferrucci L, Melzer D (2017). Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants. Am J Clin Nutr, 106(1), 130-135. Abstract.  Author URL.
Ble A, Hughes PM, Delgado J, Masoli JA, Bowman K, Zirk-Sadowski J, Mujica Mota RE, Henley WE, Melzer D (2017). Safety and Effectiveness of Statins for Prevention of Recurrent Myocardial Infarction in 12 156 Typical Older Patients: a Quasi-Experimental Study. J Gerontol a Biol Sci Med Sci, 72(2), 243-250. Abstract.  Author URL.
Delgado J, Pollard S, Pearn K, Snary EL, Black E, Prpich G, Longhurst P (2017). UK Foot and Mouth Disease: a Systemic Risk Assessment of Existing Controls. RISK ANALYSIS, 37(9), 1768-1782.  Author URL.
masoli, correa delgado, Bowman K, strain, Kuchel G, Walters K, Lafortune L, Brayne C, Melzer D, ble, et al (2016). OUTCOMES OF TREATED HYPERTENSION AT AGES 80 YEARS AND OLDER: COHORT ANALYSIS OF 79,376 PATIENTS. Journal of the American Geriatrics Society, 65, 995-1003.
Bowman K, Correa Delgado J, Henley W, Masoli J, Kos K, Brayne C, Thokala P, Lafortune L, Kuchel G, Ble A, et al (2016). Obesity in Older People with and Without Conditions Associated with Weight Loss: Follow-up of 955,000 Primary Care Patients. J Gerontol a Biol Sci Med Sci
Henriques C, Garnett K, Weatherhead EK, Lickorish FA, Forrow D, Delgado J (2015). The future water environment - Using scenarios to explore the significant water management challenges in England and Wales to 2050. Science of the Total Environment, 512-513, 381-396. Abstract.
Delgado J, Pollard S, Snary E, Black E, Prpich G, Longhurst P (2013). A Systems Approach to the Policy-Level Risk Assessment of Exotic Animal Diseases: Network Model and Application to Classical Swine Fever. RISK ANALYSIS, 33(8), 1454-1472.  Author URL.
Delgado J, Longhurst P, Hickman GAW, Gauntlett DM, Howson SF, Irving P, Hart A, Pollard SJT (2010). Intervention strategies for carcass disposal: Pareto analysis of exposures for exotic disease outbreaks. Environmental Science and Technology, 44(12), 4416-4425. Abstract.
Molander L, Gustafson Y, Lövheim H (2010). Longitudinal associations between blood pressure and dementia in the very old. Dement Geriatr Cogn Disord, 30(3), 269-276. Abstract.  Author URL.

Conferences

Masoli JAH, Correa Delgado J, Bowman K, Ble A, Han Y, Henley W, welsh S, kuchel G, ferrucci L, Melzer D, et al (In Press). Twenty Year Blood Pressure Trajectories in 46,634 Older Patients. International Congress of the European Union Geriatric Society. Abstract.
Turkmen D, Masoli JAH, Delgado J, Kuo C-L, Bowden J, Melzer D, Pilling LC (2022). Calcium Channel Blockers: Clinical Outcome Associations with Reported Pharmacogenetics Variants in 32,000 Patients.  Author URL.
Delgado J, Evans P, Gray DP, Sidaway-Lee K, Allan L, Clare L, Ballard C, Masoli J, Valderas J, Melzer D, et al (2022). OP45 Continuity of general practitioner care for patients with dementia: impact on prescribing and the health of patients. SSM Annual Scientific Meeting.
Kuo C-L, Pilling L, Atkins J, Masoli J, Delgado J, Kuchel G, Melzer D, Levine M (2021). Antipsychotic Prescribing in VA-Contracted Community Nursing Homes and Incident Use Among Veterans.
Masoli J, Atkins J, Delgado J, Pilling L, Melzer D (2021). BEING NON-FRAIL AND FREE FROM CARDIOVASCULAR DISEASE REDUCES COVID-19 RISK IN 269,164 OLDER UK BIOBANK PARTICIPANTS.  Author URL.
Kuo C-L, Pilling L, Atkins J, Masoli J, Delgado J, Kuchel G, Melzer D, Levine M (2021). Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants.
Masoli J, Kuo CL, Atkins J, Pilling L, Delgado J, Kuchel G, Melzer D (2021). DEMENTIA, ApoE AND COVID-19 SEVERITY.  Author URL.
Atkins J, Masoli J, Delgado J, Pilling L, Kuo C-L, Kuchel G, Melzer D (2021). Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort.
Atkins JL, Delgado J, Pilling LC, Bowman K, Masoli JAH, Kuchel GA, Ferrucci L, Melzer D (2018). #IDEAL CARDIOVASCULAR RISK PROFILES AND AGEING: EVIDENCE FROM 421,000 OLDER PERSONS IN TWO COHORTS.  Author URL.

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