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University of Exeter Medical School

Dr Ilianna Lourida

Dr Ilianna Lourida

Research Fellow

 I.Lourida@exeter.ac.uk

 South Cloisters 

 

South Cloisters, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK


Overview

Ilianna is a NIHR Dementia Capacity Building Research Fellow. She is currently contributing to a number of projects: i) Drug repurposing for dementia risk reduction, ii) the iWHELD study including an online support programme created specifically to support care homes and their staff in Improving the Wellbeing and Health for People Living with Dementia, iii) Processes of care in dementia community care and tools to assess the perspectives of people living with dementia and their companions/carers, iv) the ENLIVEN project which aims to increase access to natural environments for older people experiencing cognitive impairment.

Her research interests include primary and secondary prevention of cognitive decline and dementia. Her main interest is understanding relationships between modifiable risk factors (genetics) and dementia using longitudinal data analysis and evidence synthesis methods. Ilianna is also interested in ways to assess and improve quality of dementia care across settings.

She has previously been a member of the Evidence Synthesis Team and led projects focusing on evidence-based practice to improve dementia care including the impact of interventions to improve experience of care for people with dementia in hospital, and implementation strategies to improve dementia care across settings.

Research Networks:

Ilianna is a member and ECR co-lead of the Deep Dementia Phenotyping (DEMON) Network, an international initiative promoting the application of data science and artificial intelligence to dementia research with over 1,500 innovators.

She co-leads a Special Interest Group in Brain Health and Dementia Prevention formed within the DEM-COMM programme which is funded by the NIHR and the Alzheimer's Society.

Qualifications

  • PhD in Medical Studies (University of Exeter, UK)
  • MSc Health Psychology (University of Surrey, UK)
  • Ptychion in Psychology (University of Crete, Greece)

Research group links

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Publications

Journal articles

Ranson J, Llewellyn D, Lourida I (In Press). Harnessing the potential of machine learning and artificial intelligence for dementia research. Brain Informatics Abstract.
Hendriks S, Ranson JM, Peetoom K, Lourida I, Tai XY, de Vugt M, Llewellyn DJ, Köhler S (2024). Risk Factors for Young-Onset Dementia in the UK Biobank. JAMA Neurol, 81(2), 134-142. Abstract.  Author URL.
Winchester LM, Harshfield EL, Shi L, Badhwar A, Khleifat AA, Clarke N, Dehsarvi A, Lengyel I, Lourida I, Madan CR, et al (2023). Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia. Alzheimers Dement, 19(12), 5860-5871. Abstract.  Author URL.
Doherty T, Yao Z, Khleifat AAL, Tantiangco H, Tamburin S, Albertyn C, Thakur L, Llewellyn DJ, Oxtoby NP, Lourida I, et al (2023). Artificial intelligence for dementia drug discovery and trials optimization. Alzheimers Dement, 19(12), 5922-5933. Abstract.  Author URL.
Bettencourt C, Skene N, Bandres-Ciga S, Anderson E, Winchester LM, Foote IF, Schwartzentruber J, Botia JA, Nalls M, Singleton A, et al (2023). Artificial intelligence for dementia genetics and omics. Alzheimer's and Dementia, 19(12), 5905-5921. Abstract.
Newby D, Orgeta V, Marshall CR, Lourida I, Albertyn CP, Tamburin S, Raymont V, Veldsman M, Koychev I, Bauermeister S, et al (2023). Artificial intelligence for dementia prevention. Alzheimer's and Dementia, 19(12), 5952-5969. Abstract.
Bucholc M, James C, Khleifat AA, Badhwar A, Clarke N, Dehsarvi A, Madan CR, Marzi SJ, Shand C, Schilder BM, et al (2023). Artificial intelligence for dementia research methods optimization. Alzheimers Dement, 19(12), 5934-5951. Abstract.  Author URL.
Lyall DM, Kormilitzin A, Lancaster C, Sousa J, Petermann-Rocha F, Buckley C, Harshfield EL, Iveson MH, Madan CR, McArdle R, et al (2023). Artificial intelligence for dementia-Applied models and digital health. Alzheimers Dement, 19(12), 5872-5884. Abstract.  Author URL.
Borchert RJ, Azevedo T, Badhwar A, Bernal J, Betts M, Bruffaerts R, Burkhart MC, Dewachter I, Gellersen HM, Low A, et al (2023). Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: a systematic review. Alzheimers Dement, 19(12), 5885-5904. Abstract.  Author URL.
Marzi SJ, Schilder BM, Nott A, Frigerio CS, Willaime-Morawek S, Bucholc M, Hanger DP, James C, Lewis PA, Lourida I, et al (2023). Artificial intelligence for neurodegenerative experimental models. Alzheimers Dement, 19(12), 5970-5987. Abstract.  Author URL.
Costanzo E, Lengyel I, Parravano M, Biagini I, Veldsman M, Badhwar A, Betts M, Cherubini A, Llewellyn DJ, Lourida I, et al (2023). Ocular Biomarkers for Alzheimer Disease Dementia. JAMA Ophthalmology, 141(1), 84-84. Abstract.
Abbott R, Thompson Coon J, Bethel A, Rogers M, Whear R, Orr N, Garside R, Goodwin V, Mahmoud A, Lourida I, et al (2023). PROTOCOL: Health and social care interventions in the 80 years old and over population: an evidence and gap map. Campbell Systematic Reviews, 19(2). Abstract.
Bennett HQ, Kingston A, Lourida I, Robinson L, Corner L, Brayne C, Matthews FE, Jagger C (2022). A comparison over 2 decades of disability-free life expectancy at age 65 years for those with long-term conditions in England: Analysis of the 2 longitudinal Cognitive Function and Ageing Studies. PLOS Medicine, 19(3), e1003936-e1003936. Abstract.
Abbott RA, Rogers M, Lourida I, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore D, Hussey C, et al (2022). New horizons for caring for people with dementia in hospital: the DEMENTIA CARE pointers for service change. Age and Ageing, 51(9). Abstract.
Shepherd J, Lourida I, Meertens RM (2022). Radiographer-led discharge for emergency care patients, requiring projection radiography of minor musculoskeletal injuries: a scoping review. BMC Emerg Med, 22(1). Abstract.  Author URL.
Lourida I, Bennett HQ, Beyer F, Kingston A, Jagger C (2022). The impact of long-term conditions on disability-free life expectancy: a systematic review. PLOS Global Public Health, 2(8), e0000745-e0000745. Abstract.
Lourida I, Boer JMA, Teh R, Kerse N, Mendonça N, Rolleston A, Sette S, Tapanainen H, Turrini A, Virtanen SM, et al (2021). Association of Daily Physical Activity and Sedentary Behaviour with Protein Intake Patterns in Older Adults: a Multi-Study Analysis across Five Countries. Nutrients, 13(8). Abstract.  Author URL.
Bennett HQ, Kingston A, Lourida I, Robinson L, Corner L, Brayne CE, Matthews FE, Jagger C (2021). The contribution of multiple long-term conditions to widening inequalities in disability-free life expectancy over two decades: Longitudinal analysis of two cohorts using the Cognitive Function and Ageing Studies. EClinicalMedicine, 39 Abstract.  Author URL.
Lourida I, Gwernan-Jones R, Abbott R, Rogers M, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore D, et al (2020). Activity interventions to improve the experience of care in hospital for people living with dementia: a systematic review. BMC Geriatr, 20(1). Abstract.  Author URL.
Gwernan-Jones R, Abbott R, Lourida I, Rogers M, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore DA, et al (2020). The experiences of hospital staff who provide care for people living with dementia: a systematic review and synthesis of qualitative studies. INTERNATIONAL JOURNAL OF OLDER PEOPLE NURSING, 15(4). Author URL.
Gwernan-Jones R, Lourida I, Abbott RA, Rogers M, Green C, Ball S, Hemsley A, Cheeseman D, Clare L, Moore D, et al (2020). Understanding and improving experiences of care in hospital for people living with dementia, their carers and staff: three systematic reviews. Health Services and Delivery Research, 8(43), 1-248. Abstract.
Lourida I, Hannon E, Littlejohns TJ, Langa KM, Hyppönen E, Kuzma E, Llewellyn DJ (2019). Association of Lifestyle and Genetic Risk with Incidence of Dementia. JAMA - Journal of the American Medical Association Abstract.
Lourida I, Kuzma E, Llewelyn DJ (2019). Healthy Diet and Risk of Dementia in Older Adults-Reply. JAMA, 322(24). Author URL.
Kuzma E, Lourida I, Moore SF, Levine DA, Ukoumunne O, Llewellyn D (2018). Stroke and dementia risk: a systematic review and meta-analysis. Alzheimer's & Dementia: the Journal of the Alzheimer's Association, 1-11. Abstract.
Kuźma E, Hannon E, Zhou A, Lourida I, Bethel A, Levine DA, Lunnon K, Thompson-Coon J, Hyppönen E, Llewellyn DJ, et al (2018). Which Risk Factors Causally Influence Dementia? a Systematic Review of Mendelian Randomization Studies. J Alzheimers Dis, 64(1), 181-193. Abstract.  Author URL.
Kuźma E, Airdrie J, Littlejohns TJ, Lourida I, Thompson-Coon J, Lang IA, Scrobotovici M, Thacker EL, Fitzpatrick A, Kuller LH, et al (2017). Coronary Artery Bypass Graft Surgery and Dementia Risk in the Cardiovascular Health Study. Alzheimer Disease and Associated Disorders, 31(2), 120-127. Abstract.
Lourida I, Abbott RA, Rogers M, Lang IA, Stein K, Kent B, Thompson Coon J (2017). Dissemination and implementation research in dementia care: a systematic scoping review and evidence map. BMC Geriatrics, 17(1). Abstract.
Lourida I, Thompson-Coon J, Dickens CM, Soni M, Kuźma E, Kos K, Llewellyn DJ (2015). Parathyroid hormone, cognitive function and dementia: a systematic review. PLoS One, 10(5). Abstract.  Author URL.
Lourida I, Soni M, Thompson-Coon J, Purandare N, Lang IA, Ukoumunne OC, Llewellyn DJ (2013). Mediterranean diet, cognitive function, and dementia: a systematic review. Epidemiology, 24(4), 479-489. Abstract.  Author URL.

Conferences

Ranson JM, Khleifat AA, Lyall DM, Newby D, Winchester LM, Proitsi P, Veldsman M, Rittman T, Marzi S, Yao Z, et al (2022). The Deep Dementia Phenotyping (DEMON) Network: a global platform for innovation using data science and artificial intelligence.  Abstract.  Author URL.
Ranson J, Lourida I, Hannon E, littlejohns T, Ballard C, langa K, hypponen E, Kuzma E, Llewellyn D (2020). Genetic risk, education and incidence of dementia. Alzheimer’s Association International Conference. 27th - 31st Jul 2020.
Ranson JM, Lourida I, Hannon E, Littlejohns TJ, Ballard C, Langa KM, Hyppönen E, Kuzma E, Llewellyn DJ (2020). Genetic risk, education and incidence of dementia.
Ranson J, Lourida ILIANNA, Hannon E, littlejohns T, Ballard C, langa K, hypponen E, Kuzma E, Llewellyn D (2020). Stroke, genetic risk and incidence of dementia. Alzheimer's Association International Conference. 27th - 31st Jul 2020.
Coon JT, Abbott R, Coxon G, Day J, Lang I, Lourida I, Pearson M, Reed N, Rogers M, Stein K, et al (2016). OP68 Implementing and disseminating best practice in the care home setting: a systematic scoping review.
Lourida I, Kuzma E, Henley WE, Thompson-Coon J, Dickens CM, Langa KM, Llewellyn DJ (2015). P1‐255: Lifestyle, treatment, and cognitive decline in elderly diabetics.

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External Engagement and Impact

Conferences and invited presentations

Lourida I. State of the science for the application of data science and AI in dementia. Presentation at the launch of the Alan Turing Interest Group in Precision Dementia Medicine, May 2022

Lourida I, Gwernan Jones R, Thompson-Coon J, Abbott R, Rogers M, Moore D, Green C, Lang I, Ball S, Richards D, Clare L, Llewellyn D, Owens C, Hemsley A, Cheeseman D. (2019). Caring about Care: Improving the experience of care for people with dementia in hospital. Synthesis of qualitative and quantitative evidence. Alzheimer’s Society Annual Conference, London, UK

Kuźma E, Lourida I, Moore S, Levine DA, Ukoumunne OC, Llewellyn DJ. (2018). Stroke and dementia risk: A systematic review and meta-analysis. Alzheimer’s Research UK Annual Conference, London, UK

Kuzma E, Hannon E, Zhou A, Lourida I, Bethel A, Levine DA, Lunnon K, Thompson-Coon J, Hyppönen E, Llewellyn DJ. (2017). Which factors causally influence dementia? A systematic review of Mendelian randomisation studies. Alzheimer's & Dementia, 13(7), P1180. Alzheimer’s Association International Conference, London, UK

Lourida I, Kuzma E, Rogers M, Talens-Bou J, Hunt H, Ranson J, Thompson-Coon J, Llewellyn DJ. (2017). Development of a dementia meta-evidence database (EMANATE). Alzheimer's & Dementia, 13(7), P642–P643. Alzheimer’s Association International Conference, London, UK

Lourida I, Abbott R, Orr N, Rogers M, Thompson-Coon J, Lang I. (2017). Strategies, facilitators and barriers to change: A systematic review of implementation research within dementia care. Alzheimer's & Dementia, 13(7), P502. Alzheimer’s Association International Conference, London, UK

Lourida I, Thompson-Coon J, Llewellyn DJ. (2017). Forecasting the future publication rate of dementia-related systematic reviews. Global Evidence Summit, Cape Town, South Africa

Lourida I, Abbott R, Lang I, Rogers M, Kent B, Thompson-Coon J. (2016). Dissemination and implementation in dementia care: A systematic scoping review. Alzheimer's & Dementia, 12(7). Alzheimer’s Association International Conference, Toronto, Canada

Thompson-Coon J, Abbott R, Coxon G, Day J, Lang I, Lourida I, Pearson M, Reed N, Rogers M, Stein K, Sugavanam T, Whear R. (2016). Implementing and disseminating knowledge in the care home setting: A systematic scoping review. J Epidemiol Community Health, 70 (Suppl 1) A39. Society for Social Medicine 60th Annual Scientific Meeting, York, UK

Thompson-Coon J, Abbott R, Rogers M, Lourida I, Whear R, Lang I, Pearson M, Day J, Stein K. (2016). Challenges in synthesising evidence from implementation and dissemination studies:  experience from two systematic scoping reviews. What Works Global Summit, London, UK

Kuzma E, Airdrie J, Littlejohns TJ, Lourida I, Thompson-Coon J, Lang IA, Scrobotovici M, Thacker E, Fitzpatrick A, Kuller LH, Lopez OL, Longstreth WT, Ukoumunne OC, Llewellyn DJ. (2016). Coronary artery bypass graft surgery and dementia risk in the Cardiovascular Health Study. Alzheimer's & Dementia, 12(7), P248-P249. Alzheimer’s Association International Conference, Toronto, Canada

Lourida I, Kuzma E, Henley W, Thompson-Coon J, Dickens C, Langa KM, Llewellyn DJ. (2015). Lifestyle, treatment and cognitive decline in elderly diabetics. Alzheimer's & Dementia, 11(7), P451. Alzheimer’s Association International Conference, Washington DC, USA

Lourida I, Soni M, Kuzma E, Thompson-Coon J, Dickens CM, Kos K, Llewellyn DJ. (2014). Do parathyroid hormone levels play a role in dementia? A systematic review. Alzheimer's & Dementia, 10(4), P591–P592. Alzheimer’s Association International Conference, Copenhagen, Denmark

Lourida I, Soni M, Thompson-Coon J, Purandare N, Lang I, Ukoumunne OC, Llewellyn DJ. (2012). Adherence to Mediterranean diet, cognitive function and dementia: A systematic review.  2nd International Congress on Neurology and Epidemiology, Nice, France


Media Coverage

Selected:

The Guardian (2023): https://www.theguardian.com/society/2023/dec/26/alcohol-loneliness-increase-risk-early-onset-dementia

BBC News (2023): https://www.bbc.co.uk/news/health-67824447

US News (2022): https://www.usnews.com/news/health-news/articles/2022-03-17/people-are-now-living-more-years-in-good-health-study

The Guardian (2019): https://www.theguardian.com/society/2019/jul/14/healthy-lifestyle-may-cut-risk-of-dementia-regardless-of-genes

New Scientist (2019): https://institutions.newscientist.com/article/2209798-healthy-living-lowers-chances-of-dementia-even-if-genetic-risk-is-high/

New York Times (2019): https://www.nytimes.com/2019/07/16/well/mind/healthy-lifestyle-may-reduce-dementia-risk.html

The Guardian (2018): https://www.theguardian.com/science/2018/aug/31/suffering-stroke-can-double-risk-of-dementia-study-finds

The Times (2018): https://www.thetimes.co.uk/article/strokes-may-double-risk-of-dementia-gc3jt095s

G8 Dementia Summit letter: http://www.foodforthebrain.org/media/440257/igedpreventionstatementg8_2014__2_.pdf

Huffington Post: http://www.huffingtonpost.com/2013/09/04/mediterranean-diet-brain-cognitive-functioning-alzheimers_n_3860798.html?utm_hp_ref=healthy-living

The Independent (2013): https://www.independent.co.uk/life-style/health-and-families/health-news/mediterranean-diet-may-reduce-dementia-risk-8796419.html


Other

Blogging:

The Conversation UK (2013): https://theconversation.com/proof-that-the-mediterranean-diet-is-good-for-your-brain-18530

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Teaching

2021/22

Key Approaches in Health Research (CSC2022): Contributing to teaching

2018/19

Measurement and Evaluation in Health Research (CSC2016): Module co-lead

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