COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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Dr Clare Thorn

Dr Clare Thorn

Senior Lecturer

 2346

 01392 722346

 South Cloisters 

 

South Cloisters, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK

Overview

Clare is a Research Fellow in NIHR Exeter Clinical Research Facility and a Lecturer at the University of Exeter Medical School, College of Medicine and Health. Clare graduated in Physics from University College London, gained a Masters in Radiation Physics as part of her professional training as a Medical Physicist and was awarded her PhD in the study of the microcirculation using non-invasive optical techniques. Following postdoctoral positions at University College London working on cerebral haemodynamics in neonates she worked as a hospital Medical Physicist and then in the Water Industry before she joined the Diabetes and Vascular Research Centre.

Clare develops novel non-invasive optical techniques to study the haemodynamics and oxygenation of the microcirculation in health and disease. Her research includes collaboration with industrial partners to develop and validate medical instrumentation.

Clare teaches and supports students on the BSc Medical Imaging programme. She is module lead for Medical Imaging – Digital Image Processing for Radiographers and is an academic and personal tutor.

Qualifications

  • PhD
  • PCAP
  • FHEA
  • MSc
  • BSc

Teaching:

Clare teaches and supports students on the BSc Medical Imaging programme. She is module lead for Medical Imaging – Digital Image Processing for Radiographers (PAM3012) and is an academic and personal tutor. She is a PhD/MPhil supervisor.

Research

Research projects

The regulation of the microvascular in health and disease. Using visible and near infrared spectroscopic techniques to assess the relationship between perfusion, tissue oxygenation and oxygen extraction. The research includes the role of vasomotion in these processes.

The effects of Intermittent Pneumatic Compression on the microcirculation. A study funded by industrial partners to investigate the mechanisms that prevent deep vein thrombosis and treat venous insufficiency and its complications.

Does improving venous return increase microvascular perfusion? A studentship funded by a philanthropic donation and in kind contributions from industry to explore the control of the venous circulation in vivo and in vitro.

Development and Validation of a Universal Spectroscopic Device Calibrator for the Assessment of Tissue Oxygenation. A study funded by an MRC Proximity to Discovery Award and in kind contributions from industry to develop an in-vitro bovine preparation to validate medical spectroscopic instrumentation.

Optimising dermatological photodynamic therapy effectiveness using a novel radiative transfer model. A studentship funded by the Wellcome Trust’s Institutional Strategic Support Fund in the Centre for Biomedical Modelling and Analysis.

Grants/Funding:

  • OPED  GmbH Effect of Intermittent Pneumatic Compression on the microcirculation
  • MRC Proximity to Discovery Award in collaboration with Moor Instruments Ltd.
  • Philanthropic Donor: The role of veins in the control of the microcirculation
  • Wellcome Trust Institutional Strategic Support Fund
  • Daphne Jackson Fellowship

 

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Thorn CE (In Press). Microstructure and mechanics of human resistance arteries. American Journal of Physiology - Heart and Circulatory Physiology Full text.
Qiu X, Bailey H, Thorne C (2021). Barriers and Facilitators Associated with Vaccine Acceptance and Uptake Among Pregnant Women in High Income Countries: a Mini-Review. Front Immunol, 12 Abstract.  Author URL.
Thorn CE, Adio AO, Fox RH, Gardner AM, Winlove CP, Shore AC (2021). Intermittent compression induces transitory hypoxic stimuli, upstream vasodilation and enhanced perfusion of skin capillaries, independent of age and diabetes. J Appl Physiol (1985), 130(4), 1072-1084. Abstract.  Author URL.  Full text.
Asad H, Collins IJ, Goodall RL, Crichton S, Hill T, Doerholt K, Foster C, Lyall H, Post FA, Welch S, et al (2021). Mortality and AIDS-defining events among young people following transition from paediatric to adult HIV care in the UK. HIV Medicine Abstract.
Toledo G, Côté HCF, Adler C, Thorne C, Goetghebuer T (2021). Neurological development of children who are HIV-exposed and uninfected. Dev Med Child Neurol Abstract.  Author URL.
Patel K, Smith C, Collins IJ, Goodall R, Abrams EJ, Sohn AH, Mohamed TJ, Van Dyke RB, Rojo P, Wools-Kaloustian K, et al (2020). Outcomes of second-line antiretroviral therapy among children living with HIV: a global cohort analysis. Journal of the International AIDS Society, 23(4). Abstract.
Aizawa K, Ramalli A, Sbragi S, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2019). Arterial wall shear rate response to reactive hyperaemia is markedly different between young and older humans. J Physiol, 597(16), 4151-4163. Abstract.  Author URL.  Full text.
Rasi V, Cortina-Borja M, Peters H, Sconza R, Thorne C (2019). Brief Report: Surveillance of Congenital Anomalies after Exposure to Raltegravir or Elvitegravir during Pregnancy in the United Kingdom and Ireland, 2008-2018. Journal of Acquired Immune Deficiency Syndromes, 80(3), 264-268. Abstract.
Galli L, Crichton S, Buzzoni C, Goetghebuer T, Jourdain G, Judd A, Klein N, José Mellado M, José Mellado M, Noguera-Julian A, et al (2019). CD4 recovery following antiretroviral treatment interruptions in children and adolescents with HIV infection in Europe and Thailand. HIV Medicine, 20(7), 456-472. Abstract.
Collins IJ, Wools-Kaloustian K, Goodall R, Smith C, Abrams EJ, Ben-Farhat J, Balkan S, Davies MA, Edmonds A, Leroy V, et al (2019). Incidence of switching to second-line antiretroviral therapy and associated factors in children with HIV: an international cohort collaboration. The Lancet HIV, 6(2), e105-e115. Abstract.
Willemse S, Smit C, Sogni P, Sarcletti M, Uberti-Foppa C, Wittkop L, Raben D, D'Arminio Monforte A, Dabis F, Van Der Valk M, et al (2019). Low compliance with hepatocellular carcinoma screening guidelines in hepatitis B/C virus co-infected HIV patients with cirrhosis. Journal of Viral Hepatitis, 26(10), 1224-1228.
Vannappagari V, Thorne C (2019). Pregnancy and Neonatal Outcomes Following Prenatal Exposure to Dolutegravir. Journal of Acquired Immune Deficiency Syndromes, 81(4), 371-378. Abstract.
Chiappini E, Ene L, Galli L, Giaquinto C, Goetghebuer T, Judd A, Malyuta R, Noguera-Julian A, Ramos Amador JT, Rojo-Conejo P, et al (2019). Severe haematologic toxicity is rare in high risk HIV-exposed infants receiving combination neonatal prophylaxis. HIV Medicine, 20(5), 291-307. Abstract.
Chappell E, Lyall H, Riordan A, Thorne C, Foster C, Butler K, Prime K, Bamford A, Peters H, Judd A, et al (2019). The cascade of care for children and adolescents with HIV in the UK and Ireland, 2010 to 2016. Journal of the International AIDS Society, 22(9). Abstract.
Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2018). Brachial artery vasodilatory response and wall shear rate determined by multigate Doppler in a healthy young cohort. J Appl Physiol (1985), 124(1), 150-159. Abstract.  Author URL.  Full text.
Monge S, Mocroft A, Sabin A, Touloumi G, Sighem A, Abgrall S, Dray-Spira R, Spire B, Castagna A, Mussini C, et al (2018). Immunological and virological response to antiretroviral treatment in migrant and native men and women in Western Europe; is benefit equal for all?. HIV Medicine, 19(1), 42-48. Abstract.
Favarato G, Bailey H, Burns F, Prieto L, Soriano-Arandes A, Thorne C (2018). Migrant women living with HIV in Europe: Are they facing inequalities in the prevention of mother-to-child-transmission of HIV?. European Journal of Public Health, 28(1), 55-60. Abstract.
Peters H, Thorne C, Tookey PA, Byrne L (2018). National audit of perinatal HIV infections in the UK, 2006–2013: what lessons can be learnt?. HIV Medicine, 19(4), 280-289. Abstract.
Meertens RM, Casanova F, Knapp KM, Thorn C, Strain WD (2018). Use of Near-Infrared Systems for Investigations of Hemodynamics in Human in Vivo Bone Tissue: a Systematic Review. Journal of Orthopaedic Research Full text.
Thorn CE, Knight B, Pastel E, McCulloch LJ, Patel B, Shore AC, Kos K (2017). Adipose tissue is influenced by hypoxia of obstructive sleep apnea syndrome independent of obesity. Diabetes Metab, 43(3), 240-247. Abstract.  Author URL.
Chereau F, Madec Y, Sabin C, Obel N, Ruiz-Mateos E, Chrysos G, Fidler S, Lehmann C, Zangerle R, Wittkop L, et al (2017). Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers. PLoS ONE, 12(4). Abstract.
Vellinga NAR, Boerma EC, Koopmans M, Donati A, Dubin A, Shapiro NI, Pearse RM, van der Voort PHJ, Dondorp AM, Bafi T, et al (2017). Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis. Critical Care, 21(1). Abstract.
Byrne L, Sconza R, Foster C, Tookey PA, Cortina-Borja M, Thorne C (2017). Pregnancy incidence and outcomes in women with perinatal HIV infection. AIDS, 31(12), 1745-1753. Abstract.
Judd A, Collins IJ, Lodi S, Olson A, Pantazis N, Del Amo J, Duff C, Gennotte AF, Kristensen D, Ledergerber B, et al (2016). Children and young people with perinatal HIV in Europe: Epidemiological situation in 2014 and implications for the future. Eurosurveillance, 21(10). Abstract.
Desmonde S, Goetghebuer T, Thorne C, Leroy V (2016). Health and survival of HIV perinatally exposed but uninfected children born to HIV-infected mothers. Current Opinion in HIV and AIDS, 11(5), 465-476. Abstract.
Cortina-Borja M, Williams D, Peckham CS, Bailey H, Thorne C (2016). Hepatitis C virus seroprevalence in pregnant women delivering live-born infants in North Thames, England in 2012. Epidemiology and Infection, 144(3), 627-634. Abstract.
Pediatric AIDS-Defining Cancer Project Working Group for IeDEA Southern Africa, TApHOD, and COHERE in EuroCoord, Rohner E, Schmidlin K, Zwahlen M, Chakraborty R, Clifford G, Obel N, Grabar S, Verbon A, Noguera-Julian A, et al (2016). Kaposi Sarcoma Risk in HIV-Infected Children and Adolescents on Combination Antiretroviral Therapy from Sub-Saharan Africa, Europe, and Asia. Clin Infect Dis, 63(9), 1245-1253. Abstract.  Author URL.
Thorn CE, Shore AC (2016). The role of perfusion in the oxygen extraction capability of skin and skeletal muscle. Am J Physiol Heart Circ Physiol, 310(10), H1277-H1284. Abstract.  Author URL.
Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW, et al (2015). Blood Oxygen Saturation After Ischemia is Altered with Abnormal Microvascular Reperfusion. Microcirculation, 22(4), 294-305. Abstract.  Author URL.
Vellinga NAR, Boerma EC, Koopmans M, Donati A, Dubin A, Shapiro NI, Pearse RM, Machado FR, Fries M, Akarsu-Ayazoglu T, et al (2015). International study on microcirculatory shock occurrence in acutely Ill patients. Critical Care Medicine, 43(1), 48-56. Abstract.
Late presenters working group in COHERE in EuroCoord, Mocroft A, Lundgren J, Antinori A, Monforte AD, Brännström J, Bonnet F, Brockmeyer N, Casabona J, Castagna A, et al (2015). Late presentation for HIV care across Europe: update from the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study, 2010 to 2013. Euro Surveill, 20(47). Abstract.  Author URL.
Huntington S, Thorne C, Newell ML, Anderson J, Taylor GP, Pillay D, Hill T, Tookey PA, Sabin C, Ainsworth J, et al (2015). Pregnancy is associated with elevation of liver enzymes in HIV-positive women on antiretroviral therapy. AIDS, 29(7), 801-809. Abstract.
Bagkeris E, Malyuta R, Volokha A, Cortina-Borja M, Bailey H, Townsend CL, Thorne C (2015). Pregnancy outcomes in hiv-positive women in ukraine, 2000-12 (european collaborative study in eurocoord): an observational cohort study. The Lancet HIV, 2(9), e385-e392. Abstract.
Huntington S, Thorne C, Newell ML, Anderson J, Taylor GP, Pillay D, Hill T, Tookey PA, Sabin C, Ainsworth J, et al (2015). The risk of viral rebound in the year after delivery in women remaining on antiretroviral therapy. AIDS, 29(17), 2269-2278. Abstract.
Zangerle R, Touloumi G, Warszawski J, Meyer L, Dabis F, Krause MM, Ghosn J, Leport C, Reiss P, Wit F, et al (2014). Delayed HIV diagnosis and initiation of antiretroviral therapy: Inequalities by educational level, COHERE in EuroCoord. AIDS, 28(15), 2297-2306. Abstract.
Blake E, Allen J, Thorn C, Shore A, Curnow A (2013). Effect of an oxygen pressure injection (OPI) device on the oxygen saturation of patients during dermatological methyl aminolevulinate photodynamic therapy. Lasers in Medical Science, 28(3), 997-1005. Abstract.  Full text.
Blake E, Allen J, Thorn C, Shore A, Curnow A (2013). Effect of an oxygen pressure injection (OPI) device on the oxygen saturation of patients during dermatological methyl aminolevulinate photodynamic therapy. Lasers Med Sci, 28(3), 997-1005. Abstract.  Author URL.
French CE, Tookey PA, Cortina-Borja M, De Ruiter A, Townsend CL, Thorne C (2013). Inluence of short-course antenatal antiretroviral therapy on viral load and mother-to-child transmission in subsequent pregnancies among HIV-infected women. Antiviral Therapy, 18(2), 183-192. Abstract.
Adingupu DD, Thorn C, Casanova F, Elyas S, Gates PE, Strain WD, Shore AC (2013). Microvascular autoregulatory response to ischaemia in the skin and association with mean blood oxygen saturation. JOURNAL OF HUMAN HYPERTENSION, 27(10), 640-641. Author URL.
Ledergerber B, Costagliola D, Lodwick R, Torti C, van Sighem A, Podzamczer D, Mocroft A, Dorrucci M, Masquelier B, Gunthard HF, et al (2013). Predictors of CD4(+) T-Cell Counts of HIV Type 1-Infected Persons After Virologic Failure of all 3 Original Antiretroviral Drug Classes. JOURNAL OF INFECTIOUS DISEASES, 207(5), 759-767. Author URL.
Elyas S, Adingupu D, Thorn C, Gates PE, Shore AC, Strain WD (2013). Skin microvascular function is impaired in patients with small vessel disease stroke but not in patients with large vessel disease stroke when compared to healthy controls. CEREBROVASCULAR DISEASES, 35, 521-521. Author URL.
Adingupu DD, Elyas S, Thorn CE, Gates PE, Shore AC, Strain WD (2013). The prevalence of abnormal microvascular response (peaks) in stroke or transient ischaemic attack (TIA) patients compared with Controls and association with impaired sympathetic activity. CEREBROVASCULAR DISEASES, 35, 547-547. Author URL.
Chiappini E, Galli L, Giaquinto C, Ene L, Goetghebuer T, Judd A, Lisi C, Malyuta R, Noguera-Julian A, Ramos JT, et al (2013). Use of combination neonatal prophylaxis for the prevention of mother-to-child transmission of HIV infection in European high-risk infants. AIDS, 27(6), 991-1000. Abstract.
Young J, Psichogiou M, Meyer L, Ayayi S, Grabar S, Raffi F, Reiss P, Gazzard B, Sharland M, Gutierrez F, et al (2012). CD4 Cell Count and the Risk of AIDS or Death in HIV-Infected Adults on Combination Antiretroviral Therapy with a Suppressed Viral Load: a Longitudinal Cohort Study from COHERE. PLOS MEDICINE, 9(3). Author URL.
Vink H, Hubble S, Wijnands KA, Thorn C, Mawson D, Roos S, Poeze M, Shore A (2012). CLINICAL ASSESSMENT OF THE ENDOTHELIAL GLYCOCALYX TO MONITOR VASCULAR DYSFUNCTION IN SEPTIC SHOCK PATIENTS. INTENSIVE CARE MEDICINE, 38, S227-S227. Author URL.
French CE, Cortina-Borja M, Thorne C, Tookey PA (2012). Incidence, patterns, and predictors of repeat pregnancies among HIV-Infected women in the United Kingdom and Ireland, 1990-2009. Journal of Acquired Immune Deficiency Syndromes, 59(3), 287-293. Abstract.
Thorn CE, Kyte H, Slaff DW, Shore AC (2011). An association between vasomotion and oxygen extraction. Am J Physiol Heart Circ Physiol, 301(2), H442-H449. Abstract.  Author URL.
Tyrrell J, Thorn C, Shore A, Campbell S, Curnow A (2011). Oxygen saturation and perfusion changes during dermatological methyl-aminolevulinate photodynamic therapy. British Journal of Dermatology Full text.
Judd A, Castro H, Gibb DM, Butler K, Lodwick RK, van Sighem A, Ramos JT, Warsawski J, Thorne C, Noguera-Julian A, et al (2011). Risk of triple-class virological failure in children with HIV: a retrospective cohort study. The Lancet, 377(9777), 1580-1587. Abstract.
England K, Thorne C, Harris H, Ramsay M, Newell ML (2011). The impact of mode of acquisition on biological markers of paediatric hepatitis C virus infection. Journal of Viral Hepatitis, 18(8), 533-541. Abstract.
Tariq S, Townsend CL, Cortina-Borja M, Duong T, Elford J, Thorne C, Tookey PA (2011). Use of zidovudine-sparing HAART in pregnant HIV-infected women in europe: 2000-2009. Journal of Acquired Immune Deficiency Syndromes, 57(4), 326-333. Abstract.
Lodwick R, Costagliola D, Reiss P, Torti C, Teira R, Dorrucci M, Ledergerber B, Mocroft A, Podzamczer D, Cozzi-Lepri A, et al (2010). Triple-class virologic failure in HIV-infected patients undergoing antiretroviral therapy for up to 10 years. Archives of Internal Medicine, 170(5), 410-419. Abstract.
Thorn CE, Matcher SJ, Meglinski IV, Shore AC (2009). Is mean blood saturation a useful marker of tissue oxygenation?. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 296(5), H1289-H1295. Author URL.
Bohlius J, Schmidlin K, Costagliola D, Fätkenheuer G, May M, Murillo AMC, Mocroft A, Bonnet F, Clifford G, Touloumi G, et al (2009). Prognosis of HIV-associated non-Hodgkin lymphoma in patients starting combination antiretroviral therapy. AIDS, 23(15), 2029-2037. Abstract.
Thorn CE, Shore AC, Matcher SJ (2007). Combined optical and near infrared reflectance measurements of vasomotion in both skin and underlying muscle. Proc SPIE, 6434
Malyuta R, Newell ML, Ostergren M, Thorne C, Zhilka N (2006). Prevention of mother-to-child transmission of HIV infection: Ukraine experience to date. European Journal of Public Health, 16(2), 123-127. Abstract.
Hankin C, Thorne C, Newell ML (2005). Does exposure to antiretroviral therapy affect growth in the first 18 months of life in uninfected children born to HIV-infected women?. Journal of Acquired Immune Deficiency Syndromes, 40(3), 364-370. Abstract.
Patel D, Thorne C, Fiore S, Newell ML (2005). Does highly active antiretroviral therapy increase the risk of congenital abnormalities in HIV-infected women? [5]. Journal of Acquired Immune Deficiency Syndromes, 40(1), 116-118.
Giaquinto C, Ruga E, De Rossi A, Grosch-Worner I, Mok J, de Jose I, Bates I, Hawkins F, de Guevara CL, Pena JM, et al (2005). Mother-to-child transmission of HIV infection in the era of highly active antiretroviral therapy. CLINICAL INFECTIOUS DISEASES, 40(3), 458-465. Author URL.
Thorne C (2004). Antiretroviral therapy, fat redistribution and hyperlipidaemia in HIV-infected children in Europe. AIDS, 18(10), 1443-1451. Abstract.
Thorne C, Newell ML (2003). Antenatal and neonatal antiretroviral therapy in HIV-infected women and their infants: a review of safety issues. Medycyna wieku rozwojowego, 7(4 Pt 1), 425-436. Abstract.
Thorne C, Fiore S, Rudin C, Tuomala RE, Shapiro DE, Mofenson LM (2003). Antiretroviral therapy during pregnancy and the risk of an adverse outcome [3] (multiple letters). New England Journal of Medicine, 348(5), 471-472.
Fiore S, Thorne C, Newell ML (2003). European participation in an international perinatal trial. Medycyna wieku rozwojowego, 7(4 Pt 1), 449-458. Abstract.
Thorne C, Fiore S, Pembrey L, Newell ML (2003). Pregnancy-related changes in the longer-term management of HIV-infected women in Europe. European Journal of Obstetrics and Gynecology and Reproductive Biology, 111(1), 3-8. Abstract.
Thorne C, Newell ML, Botet FA, Bohlin AB, Ferrazin A, Giaquinto C, De José Gomez I, Mok JYQ, Mur A, Peltier A, et al (2002). Older children and adolescents surviving with vertically acquired HIV infection. Journal of Acquired Immune Deficiency Syndromes, 29(4), 396-401. Abstract.
Thorne C, Newell ML, Peckham CS (2000). Disclosure of diagnosis and planning for the future in HIV-affected families in Europe. Child: Care, Health and Development, 26(1), 29-40. Abstract.
Thorne C, Newell ML (2000). Epidemiology of HIV infection in the newborn. Early Human Development, 58(1), 1-16. Abstract.
Bernardi S, Thorne C, Newell ML, Giaquinto C, Tovo PA, Rossi P (2000). Variable use of therapeutic interventions for children with human immunodeficiency virus type I infection in Europe. European Journal of Pediatrics, 159(3), 170-175. Abstract.
Newell ML, Thorne C, Pembrey L, Nicoll A, Goldberg D, Peckham C (1999). Antenatal screening for hepatitis B infection and syphilis in the UK. BJOG: an International Journal of Obstetrics and Gynaecology, 106(1), 66-71. Abstract.
Thorne C, Newell ML, Peckham CS (1999). Clinical and psychosocial service needs of children and families affected by human immunodeficiency virus in Europe. European Journal of Public Health, 9(1), 8-14. Abstract.
Thorne C, Newell ML, Bailey A, Peckham CS, Giaquinto C, Ruga E, De Rossi A, Truscia D, Grosch-Worner I, Schafer A, et al (1998). Therapeutic and other interventions to reduce the risk of mother-to-child transmission of HIV-1 in Europe. British Journal of Obstetrics and Gynaecology, 105(7), 704-709. Abstract.
Newell ML, Thorne C (1997). Human immunodeficiency virus infection in pregnancy. Fetal and Maternal Medicine Review, 9(4), 223-241.
Newell ML, Thorne C (1997). Pregnancy and HIV infection in Europe. Acta Paediatrica, International Journal of Paediatrics, Supplement, 86(421), 10-14. Abstract.
Thorne C, Newell ML, Dunn D, Peckham C (1996). Characteristics of pregnant HIV-1 infected women in Europe. AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, 8(1), 33-42. Abstract.
Newell ML, Thorne C (1996). Pregnancy in HIV-infected women. Bailliere's Clinical Infectious Diseases, 3(1), 33-48. Abstract.
Thorne C, Newell M, Dunn D (1995). The European Collaborative Study: clinical and immunological characteristics of HIV 1‐infected pregnant women. BJOG: an International Journal of Obstetrics & Gynaecology, 102(11), 869-875. Abstract.
Scaravelli G, Thorne C, Newell ML (1995). The management of pregnancy and delivery in HIV-infected women in Europe. European Journal of Obstetrics and Gynecology, 62(1), 7-13. Abstract.
Edwards AD, Richardson C, van der Zee P, Elwell C, Wyatt JS, Cope M, Delpy DT, Reynolds EO (1993). Measurement of hemoglobin flow and blood flow by near-infrared spectroscopy. J Appl Physiol (1985), 75(4), 1884-1889. Abstract.  Author URL.
Edwards AD, Wyatt JS, Richardson C, Potter A, Cope M, Delpy DT, Reynolds EO (1990). Effects of indomethacin on cerebral haemodynamics in very preterm infants. Lancet, 335(8704), 1491-1495. Abstract.  Author URL.
Wyatt JS, Cope M, Delpy DT, Richardson CE, Edwards AD, Wray S, Reynolds EO (1990). Quantitation of cerebral blood volume in human infants by near-infrared spectroscopy. J Appl Physiol (1985), 68(3), 1086-1091. Abstract.  Author URL.
Hutchison IL, Cope M, Delpy DT, Richardson CE, Harris M (1990). The investigation of osteoradionecrosis of the mandible by near infrared spectroscopy. Br J Oral Maxillofac Surg, 28(3), 150-154. Abstract.  Author URL.
WYATT JS, EDWARDS AD, AZZOPARDI D, RICHARDSON CE, COPE M, DELPY DT, CADY EB, REYNOLDS EOR (1989). CEREBRAL HEMODYNAMICS DURING FAILURE OF OXIDATIVE-PHOSPHORYLATION FOLLOWING BIRTH ASPHYXIA. PEDIATRIC RESEARCH, 26(5), 511-511. Author URL.
EDWARDS AD, RICHARDSON CE, WYATT JS, DELPY DT, COPE M, REYNOLDS EOR (1989). EFFECT OF INDOMETHACIN ON CEREBRAL OXYGENATION AND HEMODYNAMICS IN PRETERM INFANTS INVESTIGATED BY NEAR-INFRARED SPECTROSCOPY (NIRS). PEDIATRIC RESEARCH, 26(5), 522-522. Author URL.
EDWARDS AD, WYATT JS, RICHARDSON CE, DELPY DT, COPE M, REYNOLDS EOR (1989). PRECISION OF CEREBRAL BLOOD-FLOW (CBF) MEASUREMENT BY NEAR-INFRARED SPECTROSCOPY (NIRS). PEDIATRIC RESEARCH, 26(5), 520-520. Author URL.
Delpy DT, Arridge SR, Cope M, Edwards D, Reynolds EO, Richardson CE, Wray S, Wyatt J, van der Zee P (1989). Quantitation of pathlength in optical spectroscopy. Adv Exp Med Biol, 248, 41-46. Author URL.
Edwards AD, Wyatt JS, Richardson C, Delpy DT, Cope M, Reynolds EO (1988). Cotside measurement of cerebral blood flow in ill newborn infants by near infrared spectroscopy. Lancet, 2(8614), 770-771. Abstract.  Author URL.
Wright GM, Scott LC, Richardson CE, Rai GS, Exton-Smith AN (1988). Relationship between the P300 auditory event-related potential and automated psychometric tests. Gerontology, 34(3), 134-138. Abstract.  Author URL.
ALDRIDGE R, CADY EB, COPE M, DELPY DT, REYNOLDS EOR, RICHARDSON CE, WRAY S, WYATT JS (1988). SIMULTANEOUS MEASUREMENTS OF CEREBRAL OXYGENATION AND METABOLITES BY NEAR-INFRARED (NIR) AND P-31 NUCLEAR MAGNETIC-RESONANCE (NMR) SPECTROSCOPY DURING HYPOXIA IN RATS. JOURNAL OF PHYSIOLOGY-LONDON, 396, P96-P96. Author URL.
WYATT JS, COPE M, DELPY DT, RICHARDSON CE, EDWARDS AD, WRAY SC, REYNOLDS EOR (1988). THE RESPONSE OF CEREBRAL BLOOD-VOLUME TO CHANGES IN ARTERIAL CARBON-DIOXIDE TENSION MEASURED BY NEAR-INFRARED SPECTROSCOPY IN NEWBORN-INFANTS. EARLY HUMAN DEVELOPMENT, 17(2-3), 291-291. Author URL.
WYATT JS, COPE M, DELPY DT, WRAY S, RICHARDSON C, REYNOLDS EOR (1987). RESPONSES OF CEREBRAL VASCULATURE TO CHANGES IN ARTERIAL CARBON-DIOXIDE TENSION MEASURED BY NEAR-INFRARED SPECTROSCOPY IN NEWBORN-INFANTS. PEDIATRIC RESEARCH, 22(2), 230-230. Author URL.

Chapters

Newell ML, Thorne C (2013). Ask the experts: HIV vertical transmission prevention. In  (Ed) Clinical Insights: HIV Prevention, 23-28.

Conferences

Meertens RM, Casanova F, Strain WD, Knapp K, Thorn C (2017). The use of near-infrared systems for investigations of microvascular haemodynamics in human in vivo bone tissue: a systematic review. International Society of Oxygen Transfer to Tissue Annual Meeting 2017. 19th - 23rd Aug 2017.
Thorn CE, Knight B, Laura MJ, Patel B, Shore A, Kos K (2015). OBSTRUCTIVE SLEEP APNOEA SYNDROME AFFECTS BLOOD FLOW AND OXYGENATION OF ADIPOSE TISSUE.  Author URL.
Thorn C, Kyte H, Gooding K, Shore A (2011). A reduced measure of oxygen extraction observed in the cutaneous microcirculation of obese subjects compared to normals.  Author URL.
Majekolagbe D, Strain WD, Gates PE, Elyas S, Thorn C, Shore A (2011). Post occlusive microvascular autoregulatory dysfunction is not associated with endothelium dependent or independent vasodilatation.  Author URL.
Thorn CE, Matcher SJ, Shore AC (2009). Evidence of a central respiratory oscillator observed in the cutaneous microcirculation. 14th Annual Meeting of the European Council for Cardiovascular Research.
Thorn CE, Matcher SJ, Shore AC (2009). Evidence of a central respiratory oscillator observed in the cutaneous microciruclation. British Microcirculation Society Meeting.
Thorn CE, Matcher SJ, Meglinski IV, Shore AC (2009). Is mean blood saturation a useful marker of tisue oxygenation?. 13th Annual Meeting of the European Council for Cardiovascular Research.
Hubble SMA, Thorne C, Appleboam R, Shore A (2009). THE EFFECTS OF PROTOCOLISED RESUSCITATION ON SUBLINGUAL "TRUE" CAPILLARY DENSITY AND FLOW OF CRITICALLY ILL PATIENTS WITH MACROCIRCULATORY SHOCK.  Author URL.
Hubble SMA, Thorne C, Appelboam R, Shore AC (2009). The effects of protocilised resuscitation on sublingual "true" capillary density and flow of critically ill patients with macrocirculation shock. 22nd ESICM Annual Congress.
Thorn CE, Bernjak A, Matcher SJ, Shore AC (2008). What is the clinical significance of Saturation (SmbO2) the mean oxygen content of blood?. 25th Conference of the European Society for Microcirculation.
Thom CE, Shore AC, Matcher SJ (2007). Combined optical and near infrared reflectance measurements of vasomotion in both skin and underlying muscle.  Author URL.
Gooding K, Thorn CE, Tooke JE, Shore AC (2007). Endothelial, sympathetic and myogenic activity during the skin hyperaemia response to local heating in healthy subjects. 8th World Congres for Microcirculation.
Thorn CE, Matcher SJ, Shore AC (2007). Rhythmic oscillations in blood volume observed simultaneously in skin and underlying muscle of the forearm. British Microcirculation Society Meeting.
Thorn CE, Matcher SJ, Shore AC (2006). Rhytmic oscillations in blood volume observed simultaneously in skin and underlying muscle of the forearm. 24th Conference of the European Society for Microcirculation.
Andiman W, Boucher M, Bulterys MB, Burns D, Bryson Y, de Martino M, Farley J, Fowler MG, Galli L, Hanson IC, et al (2001). Duration of ruptured membranes and vertical transmission of HIV-1: a meta-analysis from 15 prospective cohort studies.  Author URL.
Edwards AD, Richardson CE, van der Zeep P, Elwell CE, Wyatt JS, Cope M, Delpy DT, Reynolds EOR (1991). Measurement of blood flow by near infrared spectroscopy: a validation study.
Wyatt JS, Azzopardi D, Cope M, Cady EB, Richardson CE, Delpy DT, Edwards AD, Reynolds EOR (1989). Cerebral haemodynamics during the development of secondary energy failure following birth asphyxia.
Edwards AD, Wyatt JS, Richardson CE, Delpy DT, Cope M, Reynolds EOR (1989). Cotside measurement of cerebral blood flow in sick newborn infants by near infrared spectroscopy.
Edwards AD, Richardson CE, Wyatt JS, Delpy DT, Cope M, Reynolds EOR (1989). Indomethacin reduced cerebral blood flow in sick preterm infants.
Delpy DT, Arridge S, Cope M, Edwards AD, Reynolds EOR, Richardson CE, van der Zee P, Wray S, Wyatt JS (1989). Optical spectroscopy of the neonatal brain and the development of tissue-equivalent phantoms.
Edwards AD, Wyatt JS, Richardson CE, Cope M, Delpy DT, Reynolds EOR (1989). Slow infusion of Indomethacin reduces cerebral blood flow in sick preterm infants.
Wyatt JS, Azzopardi D, Cope M, Cady EB, Richardson CE, Delpy DT, Edwards D, Reynolds EOR (1988). Cerebral energy failure following birth asphyxia in newborn infants by. phosphorous MRS and near infrared spectroscopy.
Wray S, Wyatt JS, Aldridge RF, Cady EB, Cope M, Delpy DT, Reynolds EOR, Richardson CE (1988). In vivo measurement of cerebral oxygenation and phosphorous metabolites during hypoxia.

Publications by year


In Press

Thorn CE (In Press). Microstructure and mechanics of human resistance arteries. American Journal of Physiology - Heart and Circulatory Physiology Full text.

2021

Qiu X, Bailey H, Thorne C (2021). Barriers and Facilitators Associated with Vaccine Acceptance and Uptake Among Pregnant Women in High Income Countries: a Mini-Review. Front Immunol, 12 Abstract.  Author URL.
Thorn CE, Adio AO, Fox RH, Gardner AM, Winlove CP, Shore AC (2021). Intermittent compression induces transitory hypoxic stimuli, upstream vasodilation and enhanced perfusion of skin capillaries, independent of age and diabetes. J Appl Physiol (1985), 130(4), 1072-1084. Abstract.  Author URL.  Full text.
Asad H, Collins IJ, Goodall RL, Crichton S, Hill T, Doerholt K, Foster C, Lyall H, Post FA, Welch S, et al (2021). Mortality and AIDS-defining events among young people following transition from paediatric to adult HIV care in the UK. HIV Medicine Abstract.
Toledo G, Côté HCF, Adler C, Thorne C, Goetghebuer T (2021). Neurological development of children who are HIV-exposed and uninfected. Dev Med Child Neurol Abstract.  Author URL.

2020

Patel K, Smith C, Collins IJ, Goodall R, Abrams EJ, Sohn AH, Mohamed TJ, Van Dyke RB, Rojo P, Wools-Kaloustian K, et al (2020). Outcomes of second-line antiretroviral therapy among children living with HIV: a global cohort analysis. Journal of the International AIDS Society, 23(4). Abstract.

2019

Aizawa K, Ramalli A, Sbragi S, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2019). Arterial wall shear rate response to reactive hyperaemia is markedly different between young and older humans. J Physiol, 597(16), 4151-4163. Abstract.  Author URL.  Full text.
Rasi V, Cortina-Borja M, Peters H, Sconza R, Thorne C (2019). Brief Report: Surveillance of Congenital Anomalies after Exposure to Raltegravir or Elvitegravir during Pregnancy in the United Kingdom and Ireland, 2008-2018. Journal of Acquired Immune Deficiency Syndromes, 80(3), 264-268. Abstract.
Galli L, Crichton S, Buzzoni C, Goetghebuer T, Jourdain G, Judd A, Klein N, José Mellado M, José Mellado M, Noguera-Julian A, et al (2019). CD4 recovery following antiretroviral treatment interruptions in children and adolescents with HIV infection in Europe and Thailand. HIV Medicine, 20(7), 456-472. Abstract.
Collins IJ, Wools-Kaloustian K, Goodall R, Smith C, Abrams EJ, Ben-Farhat J, Balkan S, Davies MA, Edmonds A, Leroy V, et al (2019). Incidence of switching to second-line antiretroviral therapy and associated factors in children with HIV: an international cohort collaboration. The Lancet HIV, 6(2), e105-e115. Abstract.
Willemse S, Smit C, Sogni P, Sarcletti M, Uberti-Foppa C, Wittkop L, Raben D, D'Arminio Monforte A, Dabis F, Van Der Valk M, et al (2019). Low compliance with hepatocellular carcinoma screening guidelines in hepatitis B/C virus co-infected HIV patients with cirrhosis. Journal of Viral Hepatitis, 26(10), 1224-1228.
Vannappagari V, Thorne C (2019). Pregnancy and Neonatal Outcomes Following Prenatal Exposure to Dolutegravir. Journal of Acquired Immune Deficiency Syndromes, 81(4), 371-378. Abstract.
Chiappini E, Ene L, Galli L, Giaquinto C, Goetghebuer T, Judd A, Malyuta R, Noguera-Julian A, Ramos Amador JT, Rojo-Conejo P, et al (2019). Severe haematologic toxicity is rare in high risk HIV-exposed infants receiving combination neonatal prophylaxis. HIV Medicine, 20(5), 291-307. Abstract.
Chappell E, Lyall H, Riordan A, Thorne C, Foster C, Butler K, Prime K, Bamford A, Peters H, Judd A, et al (2019). The cascade of care for children and adolescents with HIV in the UK and Ireland, 2010 to 2016. Journal of the International AIDS Society, 22(9). Abstract.

2018

Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2018). Brachial artery vasodilatory response and wall shear rate determined by multigate Doppler in a healthy young cohort. J Appl Physiol (1985), 124(1), 150-159. Abstract.  Author URL.  Full text.
Monge S, Mocroft A, Sabin A, Touloumi G, Sighem A, Abgrall S, Dray-Spira R, Spire B, Castagna A, Mussini C, et al (2018). Immunological and virological response to antiretroviral treatment in migrant and native men and women in Western Europe; is benefit equal for all?. HIV Medicine, 19(1), 42-48. Abstract.
Favarato G, Bailey H, Burns F, Prieto L, Soriano-Arandes A, Thorne C (2018). Migrant women living with HIV in Europe: Are they facing inequalities in the prevention of mother-to-child-transmission of HIV?. European Journal of Public Health, 28(1), 55-60. Abstract.
Peters H, Thorne C, Tookey PA, Byrne L (2018). National audit of perinatal HIV infections in the UK, 2006–2013: what lessons can be learnt?. HIV Medicine, 19(4), 280-289. Abstract.
Meertens RM, Casanova F, Knapp KM, Thorn C, Strain WD (2018). Use of Near-Infrared Systems for Investigations of Hemodynamics in Human in Vivo Bone Tissue: a Systematic Review. Journal of Orthopaedic Research Full text.

2017

Thorn CE, Knight B, Pastel E, McCulloch LJ, Patel B, Shore AC, Kos K (2017). Adipose tissue is influenced by hypoxia of obstructive sleep apnea syndrome independent of obesity. Diabetes Metab, 43(3), 240-247. Abstract.  Author URL.
Chereau F, Madec Y, Sabin C, Obel N, Ruiz-Mateos E, Chrysos G, Fidler S, Lehmann C, Zangerle R, Wittkop L, et al (2017). Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers. PLoS ONE, 12(4). Abstract.
Vellinga NAR, Boerma EC, Koopmans M, Donati A, Dubin A, Shapiro NI, Pearse RM, van der Voort PHJ, Dondorp AM, Bafi T, et al (2017). Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis. Critical Care, 21(1). Abstract.
Byrne L, Sconza R, Foster C, Tookey PA, Cortina-Borja M, Thorne C (2017). Pregnancy incidence and outcomes in women with perinatal HIV infection. AIDS, 31(12), 1745-1753. Abstract.
Meertens RM, Casanova F, Strain WD, Knapp K, Thorn C (2017). The use of near-infrared systems for investigations of microvascular haemodynamics in human in vivo bone tissue: a systematic review. International Society of Oxygen Transfer to Tissue Annual Meeting 2017. 19th - 23rd Aug 2017.

2016

Judd A, Collins IJ, Lodi S, Olson A, Pantazis N, Del Amo J, Duff C, Gennotte AF, Kristensen D, Ledergerber B, et al (2016). Children and young people with perinatal HIV in Europe: Epidemiological situation in 2014 and implications for the future. Eurosurveillance, 21(10). Abstract.
Desmonde S, Goetghebuer T, Thorne C, Leroy V (2016). Health and survival of HIV perinatally exposed but uninfected children born to HIV-infected mothers. Current Opinion in HIV and AIDS, 11(5), 465-476. Abstract.
Cortina-Borja M, Williams D, Peckham CS, Bailey H, Thorne C (2016). Hepatitis C virus seroprevalence in pregnant women delivering live-born infants in North Thames, England in 2012. Epidemiology and Infection, 144(3), 627-634. Abstract.
Pediatric AIDS-Defining Cancer Project Working Group for IeDEA Southern Africa, TApHOD, and COHERE in EuroCoord, Rohner E, Schmidlin K, Zwahlen M, Chakraborty R, Clifford G, Obel N, Grabar S, Verbon A, Noguera-Julian A, et al (2016). Kaposi Sarcoma Risk in HIV-Infected Children and Adolescents on Combination Antiretroviral Therapy from Sub-Saharan Africa, Europe, and Asia. Clin Infect Dis, 63(9), 1245-1253. Abstract.  Author URL.
Thorn CE, Shore AC (2016). The role of perfusion in the oxygen extraction capability of skin and skeletal muscle. Am J Physiol Heart Circ Physiol, 310(10), H1277-H1284. Abstract.  Author URL.

2015

Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW, et al (2015). Blood Oxygen Saturation After Ischemia is Altered with Abnormal Microvascular Reperfusion. Microcirculation, 22(4), 294-305. Abstract.  Author URL.
Vellinga NAR, Boerma EC, Koopmans M, Donati A, Dubin A, Shapiro NI, Pearse RM, Machado FR, Fries M, Akarsu-Ayazoglu T, et al (2015). International study on microcirculatory shock occurrence in acutely Ill patients. Critical Care Medicine, 43(1), 48-56. Abstract.
Late presenters working group in COHERE in EuroCoord, Mocroft A, Lundgren J, Antinori A, Monforte AD, Brännström J, Bonnet F, Brockmeyer N, Casabona J, Castagna A, et al (2015). Late presentation for HIV care across Europe: update from the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study, 2010 to 2013. Euro Surveill, 20(47). Abstract.  Author URL.
Thorn CE, Knight B, Laura MJ, Patel B, Shore A, Kos K (2015). OBSTRUCTIVE SLEEP APNOEA SYNDROME AFFECTS BLOOD FLOW AND OXYGENATION OF ADIPOSE TISSUE.  Author URL.
Huntington S, Thorne C, Newell ML, Anderson J, Taylor GP, Pillay D, Hill T, Tookey PA, Sabin C, Ainsworth J, et al (2015). Pregnancy is associated with elevation of liver enzymes in HIV-positive women on antiretroviral therapy. AIDS, 29(7), 801-809. Abstract.
Bagkeris E, Malyuta R, Volokha A, Cortina-Borja M, Bailey H, Townsend CL, Thorne C (2015). Pregnancy outcomes in hiv-positive women in ukraine, 2000-12 (european collaborative study in eurocoord): an observational cohort study. The Lancet HIV, 2(9), e385-e392. Abstract.
Huntington S, Thorne C, Newell ML, Anderson J, Taylor GP, Pillay D, Hill T, Tookey PA, Sabin C, Ainsworth J, et al (2015). The risk of viral rebound in the year after delivery in women remaining on antiretroviral therapy. AIDS, 29(17), 2269-2278. Abstract.

2014

Zangerle R, Touloumi G, Warszawski J, Meyer L, Dabis F, Krause MM, Ghosn J, Leport C, Reiss P, Wit F, et al (2014). Delayed HIV diagnosis and initiation of antiretroviral therapy: Inequalities by educational level, COHERE in EuroCoord. AIDS, 28(15), 2297-2306. Abstract.

2013

Newell ML, Thorne C (2013). Ask the experts: HIV vertical transmission prevention. In  (Ed) Clinical Insights: HIV Prevention, 23-28.
Blake E, Allen J, Thorn C, Shore A, Curnow A (2013). Effect of an oxygen pressure injection (OPI) device on the oxygen saturation of patients during dermatological methyl aminolevulinate photodynamic therapy. Lasers in Medical Science, 28(3), 997-1005. Abstract.  Full text.
Blake E, Allen J, Thorn C, Shore A, Curnow A (2013). Effect of an oxygen pressure injection (OPI) device on the oxygen saturation of patients during dermatological methyl aminolevulinate photodynamic therapy. Lasers Med Sci, 28(3), 997-1005. Abstract.  Author URL.
French CE, Tookey PA, Cortina-Borja M, De Ruiter A, Townsend CL, Thorne C (2013). Inluence of short-course antenatal antiretroviral therapy on viral load and mother-to-child transmission in subsequent pregnancies among HIV-infected women. Antiviral Therapy, 18(2), 183-192. Abstract.
Adingupu DD, Thorn C, Casanova F, Elyas S, Gates PE, Strain WD, Shore AC (2013). Microvascular autoregulatory response to ischaemia in the skin and association with mean blood oxygen saturation. JOURNAL OF HUMAN HYPERTENSION, 27(10), 640-641. Author URL.
Ledergerber B, Costagliola D, Lodwick R, Torti C, van Sighem A, Podzamczer D, Mocroft A, Dorrucci M, Masquelier B, Gunthard HF, et al (2013). Predictors of CD4(+) T-Cell Counts of HIV Type 1-Infected Persons After Virologic Failure of all 3 Original Antiretroviral Drug Classes. JOURNAL OF INFECTIOUS DISEASES, 207(5), 759-767. Author URL.
Elyas S, Adingupu D, Thorn C, Gates PE, Shore AC, Strain WD (2013). Skin microvascular function is impaired in patients with small vessel disease stroke but not in patients with large vessel disease stroke when compared to healthy controls. CEREBROVASCULAR DISEASES, 35, 521-521. Author URL.
Adingupu DD, Elyas S, Thorn CE, Gates PE, Shore AC, Strain WD (2013). The prevalence of abnormal microvascular response (peaks) in stroke or transient ischaemic attack (TIA) patients compared with Controls and association with impaired sympathetic activity. CEREBROVASCULAR DISEASES, 35, 547-547. Author URL.
Chiappini E, Galli L, Giaquinto C, Ene L, Goetghebuer T, Judd A, Lisi C, Malyuta R, Noguera-Julian A, Ramos JT, et al (2013). Use of combination neonatal prophylaxis for the prevention of mother-to-child transmission of HIV infection in European high-risk infants. AIDS, 27(6), 991-1000. Abstract.

2012

Young J, Psichogiou M, Meyer L, Ayayi S, Grabar S, Raffi F, Reiss P, Gazzard B, Sharland M, Gutierrez F, et al (2012). CD4 Cell Count and the Risk of AIDS or Death in HIV-Infected Adults on Combination Antiretroviral Therapy with a Suppressed Viral Load: a Longitudinal Cohort Study from COHERE. PLOS MEDICINE, 9(3). Author URL.
Vink H, Hubble S, Wijnands KA, Thorn C, Mawson D, Roos S, Poeze M, Shore A (2012). CLINICAL ASSESSMENT OF THE ENDOTHELIAL GLYCOCALYX TO MONITOR VASCULAR DYSFUNCTION IN SEPTIC SHOCK PATIENTS. INTENSIVE CARE MEDICINE, 38, S227-S227. Author URL.
French CE, Cortina-Borja M, Thorne C, Tookey PA (2012). Incidence, patterns, and predictors of repeat pregnancies among HIV-Infected women in the United Kingdom and Ireland, 1990-2009. Journal of Acquired Immune Deficiency Syndromes, 59(3), 287-293. Abstract.

2011

Thorn C, Kyte H, Gooding K, Shore A (2011). A reduced measure of oxygen extraction observed in the cutaneous microcirculation of obese subjects compared to normals.  Author URL.
Thorn CE, Kyte H, Slaff DW, Shore AC (2011). An association between vasomotion and oxygen extraction. Am J Physiol Heart Circ Physiol, 301(2), H442-H449. Abstract.  Author URL.
Tyrrell J, Thorn C, Shore A, Campbell S, Curnow A (2011). Oxygen saturation and perfusion changes during dermatological methyl-aminolevulinate photodynamic therapy. British Journal of Dermatology Full text.
Majekolagbe D, Strain WD, Gates PE, Elyas S, Thorn C, Shore A (2011). Post occlusive microvascular autoregulatory dysfunction is not associated with endothelium dependent or independent vasodilatation.  Author URL.
Judd A, Castro H, Gibb DM, Butler K, Lodwick RK, van Sighem A, Ramos JT, Warsawski J, Thorne C, Noguera-Julian A, et al (2011). Risk of triple-class virological failure in children with HIV: a retrospective cohort study. The Lancet, 377(9777), 1580-1587. Abstract.
England K, Thorne C, Harris H, Ramsay M, Newell ML (2011). The impact of mode of acquisition on biological markers of paediatric hepatitis C virus infection. Journal of Viral Hepatitis, 18(8), 533-541. Abstract.
Tariq S, Townsend CL, Cortina-Borja M, Duong T, Elford J, Thorne C, Tookey PA (2011). Use of zidovudine-sparing HAART in pregnant HIV-infected women in europe: 2000-2009. Journal of Acquired Immune Deficiency Syndromes, 57(4), 326-333. Abstract.

2010

Lodwick R, Costagliola D, Reiss P, Torti C, Teira R, Dorrucci M, Ledergerber B, Mocroft A, Podzamczer D, Cozzi-Lepri A, et al (2010). Triple-class virologic failure in HIV-infected patients undergoing antiretroviral therapy for up to 10 years. Archives of Internal Medicine, 170(5), 410-419. Abstract.

2009

Thorn CE, Matcher SJ, Shore AC (2009). Evidence of a central respiratory oscillator observed in the cutaneous microcirculation. 14th Annual Meeting of the European Council for Cardiovascular Research.
Thorn CE, Matcher SJ, Shore AC (2009). Evidence of a central respiratory oscillator observed in the cutaneous microciruclation. British Microcirculation Society Meeting.
Thorn CE, Matcher SJ, Meglinski IV, Shore AC (2009). Is mean blood saturation a useful marker of tissue oxygenation?. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 296(5), H1289-H1295. Author URL.
Thorn CE, Matcher SJ, Meglinski IV, Shore AC (2009). Is mean blood saturation a useful marker of tisue oxygenation?. 13th Annual Meeting of the European Council for Cardiovascular Research.
Bohlius J, Schmidlin K, Costagliola D, Fätkenheuer G, May M, Murillo AMC, Mocroft A, Bonnet F, Clifford G, Touloumi G, et al (2009). Prognosis of HIV-associated non-Hodgkin lymphoma in patients starting combination antiretroviral therapy. AIDS, 23(15), 2029-2037. Abstract.
Hubble SMA, Thorne C, Appleboam R, Shore A (2009). THE EFFECTS OF PROTOCOLISED RESUSCITATION ON SUBLINGUAL "TRUE" CAPILLARY DENSITY AND FLOW OF CRITICALLY ILL PATIENTS WITH MACROCIRCULATORY SHOCK.  Author URL.
Hubble SMA, Thorne C, Appelboam R, Shore AC (2009). The effects of protocilised resuscitation on sublingual "true" capillary density and flow of critically ill patients with macrocirculation shock. 22nd ESICM Annual Congress.

2008

Thorn CE, Bernjak A, Matcher SJ, Shore AC (2008). What is the clinical significance of Saturation (SmbO2) the mean oxygen content of blood?. 25th Conference of the European Society for Microcirculation.

2007

Thorn CE, Shore AC, Matcher SJ (2007). Combined optical and near infrared reflectance measurements of vasomotion in both skin and underlying muscle. Proc SPIE, 6434
Thom CE, Shore AC, Matcher SJ (2007). Combined optical and near infrared reflectance measurements of vasomotion in both skin and underlying muscle.  Author URL.
Gooding K, Thorn CE, Tooke JE, Shore AC (2007). Endothelial, sympathetic and myogenic activity during the skin hyperaemia response to local heating in healthy subjects. 8th World Congres for Microcirculation.
Thorn CE, Matcher SJ, Shore AC (2007). Rhythmic oscillations in blood volume observed simultaneously in skin and underlying muscle of the forearm. British Microcirculation Society Meeting.

2006

Malyuta R, Newell ML, Ostergren M, Thorne C, Zhilka N (2006). Prevention of mother-to-child transmission of HIV infection: Ukraine experience to date. European Journal of Public Health, 16(2), 123-127. Abstract.
Thorn CE, Matcher SJ, Shore AC (2006). Rhytmic oscillations in blood volume observed simultaneously in skin and underlying muscle of the forearm. 24th Conference of the European Society for Microcirculation.

2005

Hankin C, Thorne C, Newell ML (2005). Does exposure to antiretroviral therapy affect growth in the first 18 months of life in uninfected children born to HIV-infected women?. Journal of Acquired Immune Deficiency Syndromes, 40(3), 364-370. Abstract.
Patel D, Thorne C, Fiore S, Newell ML (2005). Does highly active antiretroviral therapy increase the risk of congenital abnormalities in HIV-infected women? [5]. Journal of Acquired Immune Deficiency Syndromes, 40(1), 116-118.
Giaquinto C, Ruga E, De Rossi A, Grosch-Worner I, Mok J, de Jose I, Bates I, Hawkins F, de Guevara CL, Pena JM, et al (2005). Mother-to-child transmission of HIV infection in the era of highly active antiretroviral therapy. CLINICAL INFECTIOUS DISEASES, 40(3), 458-465. Author URL.

2004

Thorne C (2004). Antiretroviral therapy, fat redistribution and hyperlipidaemia in HIV-infected children in Europe. AIDS, 18(10), 1443-1451. Abstract.

2003

Thorne C, Newell ML (2003). Antenatal and neonatal antiretroviral therapy in HIV-infected women and their infants: a review of safety issues. Medycyna wieku rozwojowego, 7(4 Pt 1), 425-436. Abstract.
Thorne C, Fiore S, Rudin C, Tuomala RE, Shapiro DE, Mofenson LM (2003). Antiretroviral therapy during pregnancy and the risk of an adverse outcome [3] (multiple letters). New England Journal of Medicine, 348(5), 471-472.
Fiore S, Thorne C, Newell ML (2003). European participation in an international perinatal trial. Medycyna wieku rozwojowego, 7(4 Pt 1), 449-458. Abstract.
Thorne C, Fiore S, Pembrey L, Newell ML (2003). Pregnancy-related changes in the longer-term management of HIV-infected women in Europe. European Journal of Obstetrics and Gynecology and Reproductive Biology, 111(1), 3-8. Abstract.

2002

Thorne C, Newell ML, Botet FA, Bohlin AB, Ferrazin A, Giaquinto C, De José Gomez I, Mok JYQ, Mur A, Peltier A, et al (2002). Older children and adolescents surviving with vertically acquired HIV infection. Journal of Acquired Immune Deficiency Syndromes, 29(4), 396-401. Abstract.

2001

Andiman W, Boucher M, Bulterys MB, Burns D, Bryson Y, de Martino M, Farley J, Fowler MG, Galli L, Hanson IC, et al (2001). Duration of ruptured membranes and vertical transmission of HIV-1: a meta-analysis from 15 prospective cohort studies.  Author URL.

2000

Thorne C, Newell ML, Peckham CS (2000). Disclosure of diagnosis and planning for the future in HIV-affected families in Europe. Child: Care, Health and Development, 26(1), 29-40. Abstract.
Thorne C, Newell ML (2000). Epidemiology of HIV infection in the newborn. Early Human Development, 58(1), 1-16. Abstract.
Bernardi S, Thorne C, Newell ML, Giaquinto C, Tovo PA, Rossi P (2000). Variable use of therapeutic interventions for children with human immunodeficiency virus type I infection in Europe. European Journal of Pediatrics, 159(3), 170-175. Abstract.

1999

Newell ML, Thorne C, Pembrey L, Nicoll A, Goldberg D, Peckham C (1999). Antenatal screening for hepatitis B infection and syphilis in the UK. BJOG: an International Journal of Obstetrics and Gynaecology, 106(1), 66-71. Abstract.
Thorne C, Newell ML, Peckham CS (1999). Clinical and psychosocial service needs of children and families affected by human immunodeficiency virus in Europe. European Journal of Public Health, 9(1), 8-14. Abstract.

1998

Thorne C, Newell ML, Bailey A, Peckham CS, Giaquinto C, Ruga E, De Rossi A, Truscia D, Grosch-Worner I, Schafer A, et al (1998). Therapeutic and other interventions to reduce the risk of mother-to-child transmission of HIV-1 in Europe. British Journal of Obstetrics and Gynaecology, 105(7), 704-709. Abstract.

1997

Newell ML, Thorne C (1997). Human immunodeficiency virus infection in pregnancy. Fetal and Maternal Medicine Review, 9(4), 223-241.
Newell ML, Thorne C (1997). Pregnancy and HIV infection in Europe. Acta Paediatrica, International Journal of Paediatrics, Supplement, 86(421), 10-14. Abstract.

1996

Thorne C, Newell ML, Dunn D, Peckham C (1996). Characteristics of pregnant HIV-1 infected women in Europe. AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, 8(1), 33-42. Abstract.
Newell ML, Thorne C (1996). Pregnancy in HIV-infected women. Bailliere's Clinical Infectious Diseases, 3(1), 33-48. Abstract.

1995

Thorne C, Newell M, Dunn D (1995). The European Collaborative Study: clinical and immunological characteristics of HIV 1‐infected pregnant women. BJOG: an International Journal of Obstetrics & Gynaecology, 102(11), 869-875. Abstract.
Scaravelli G, Thorne C, Newell ML (1995). The management of pregnancy and delivery in HIV-infected women in Europe. European Journal of Obstetrics and Gynecology, 62(1), 7-13. Abstract.

1993

Edwards AD, Richardson C, van der Zee P, Elwell C, Wyatt JS, Cope M, Delpy DT, Reynolds EO (1993). Measurement of hemoglobin flow and blood flow by near-infrared spectroscopy. J Appl Physiol (1985), 75(4), 1884-1889. Abstract.  Author URL.

1991

Edwards AD, Richardson CE, van der Zeep P, Elwell CE, Wyatt JS, Cope M, Delpy DT, Reynolds EOR (1991). Measurement of blood flow by near infrared spectroscopy: a validation study.

1990

Edwards AD, Wyatt JS, Richardson C, Potter A, Cope M, Delpy DT, Reynolds EO (1990). Effects of indomethacin on cerebral haemodynamics in very preterm infants. Lancet, 335(8704), 1491-1495. Abstract.  Author URL.
Wyatt JS, Cope M, Delpy DT, Richardson CE, Edwards AD, Wray S, Reynolds EO (1990). Quantitation of cerebral blood volume in human infants by near-infrared spectroscopy. J Appl Physiol (1985), 68(3), 1086-1091. Abstract.  Author URL.
Hutchison IL, Cope M, Delpy DT, Richardson CE, Harris M (1990). The investigation of osteoradionecrosis of the mandible by near infrared spectroscopy. Br J Oral Maxillofac Surg, 28(3), 150-154. Abstract.  Author URL.

1989

WYATT JS, EDWARDS AD, AZZOPARDI D, RICHARDSON CE, COPE M, DELPY DT, CADY EB, REYNOLDS EOR (1989). CEREBRAL HEMODYNAMICS DURING FAILURE OF OXIDATIVE-PHOSPHORYLATION FOLLOWING BIRTH ASPHYXIA. PEDIATRIC RESEARCH, 26(5), 511-511. Author URL.
Wyatt JS, Azzopardi D, Cope M, Cady EB, Richardson CE, Delpy DT, Edwards AD, Reynolds EOR (1989). Cerebral haemodynamics during the development of secondary energy failure following birth asphyxia.
Edwards AD, Wyatt JS, Richardson CE, Delpy DT, Cope M, Reynolds EOR (1989). Cotside measurement of cerebral blood flow in sick newborn infants by near infrared spectroscopy.
EDWARDS AD, RICHARDSON CE, WYATT JS, DELPY DT, COPE M, REYNOLDS EOR (1989). EFFECT OF INDOMETHACIN ON CEREBRAL OXYGENATION AND HEMODYNAMICS IN PRETERM INFANTS INVESTIGATED BY NEAR-INFRARED SPECTROSCOPY (NIRS). PEDIATRIC RESEARCH, 26(5), 522-522. Author URL.
Edwards AD, Richardson CE, Wyatt JS, Delpy DT, Cope M, Reynolds EOR (1989). Indomethacin reduced cerebral blood flow in sick preterm infants.
Delpy DT, Arridge S, Cope M, Edwards AD, Reynolds EOR, Richardson CE, van der Zee P, Wray S, Wyatt JS (1989). Optical spectroscopy of the neonatal brain and the development of tissue-equivalent phantoms.
EDWARDS AD, WYATT JS, RICHARDSON CE, DELPY DT, COPE M, REYNOLDS EOR (1989). PRECISION OF CEREBRAL BLOOD-FLOW (CBF) MEASUREMENT BY NEAR-INFRARED SPECTROSCOPY (NIRS). PEDIATRIC RESEARCH, 26(5), 520-520. Author URL.
Delpy DT, Arridge SR, Cope M, Edwards D, Reynolds EO, Richardson CE, Wray S, Wyatt J, van der Zee P (1989). Quantitation of pathlength in optical spectroscopy. Adv Exp Med Biol, 248, 41-46. Author URL.
Edwards AD, Wyatt JS, Richardson CE, Cope M, Delpy DT, Reynolds EOR (1989). Slow infusion of Indomethacin reduces cerebral blood flow in sick preterm infants.

1988

Wyatt JS, Azzopardi D, Cope M, Cady EB, Richardson CE, Delpy DT, Edwards D, Reynolds EOR (1988). Cerebral energy failure following birth asphyxia in newborn infants by. phosphorous MRS and near infrared spectroscopy.
Edwards AD, Wyatt JS, Richardson C, Delpy DT, Cope M, Reynolds EO (1988). Cotside measurement of cerebral blood flow in ill newborn infants by near infrared spectroscopy. Lancet, 2(8614), 770-771. Abstract.  Author URL.
Wray S, Wyatt JS, Aldridge RF, Cady EB, Cope M, Delpy DT, Reynolds EOR, Richardson CE (1988). In vivo measurement of cerebral oxygenation and phosphorous metabolites during hypoxia.
Wright GM, Scott LC, Richardson CE, Rai GS, Exton-Smith AN (1988). Relationship between the P300 auditory event-related potential and automated psychometric tests. Gerontology, 34(3), 134-138. Abstract.  Author URL.
ALDRIDGE R, CADY EB, COPE M, DELPY DT, REYNOLDS EOR, RICHARDSON CE, WRAY S, WYATT JS (1988). SIMULTANEOUS MEASUREMENTS OF CEREBRAL OXYGENATION AND METABOLITES BY NEAR-INFRARED (NIR) AND P-31 NUCLEAR MAGNETIC-RESONANCE (NMR) SPECTROSCOPY DURING HYPOXIA IN RATS. JOURNAL OF PHYSIOLOGY-LONDON, 396, P96-P96. Author URL.
WYATT JS, COPE M, DELPY DT, RICHARDSON CE, EDWARDS AD, WRAY SC, REYNOLDS EOR (1988). THE RESPONSE OF CEREBRAL BLOOD-VOLUME TO CHANGES IN ARTERIAL CARBON-DIOXIDE TENSION MEASURED BY NEAR-INFRARED SPECTROSCOPY IN NEWBORN-INFANTS. EARLY HUMAN DEVELOPMENT, 17(2-3), 291-291. Author URL.

1987

WYATT JS, COPE M, DELPY DT, WRAY S, RICHARDSON C, REYNOLDS EOR (1987). RESPONSES OF CEREBRAL VASCULATURE TO CHANGES IN ARTERIAL CARBON-DIOXIDE TENSION MEASURED BY NEAR-INFRARED SPECTROSCOPY IN NEWBORN-INFANTS. PEDIATRIC RESEARCH, 22(2), 230-230. Author URL.

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