University of Exeter Medical School

Professor Chris Fox

Professor Chris Fox

Professor of Clinical Psychiatry

 Christopher.Fox@exeter.ac.uk

 07411 746549

 College House 

 

College House, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK

Overview

Chris Fox is an expert in mental health and dementia research.  He spent 6 years training in psychiatry and researching trauma/personality assessments and treatment and psychometric assessment development with the Ministry of Defence. Then he went into the NHS and trained in Oxford undertaking an MD on anger characterisation in elderly mentally ill patients at UCL. He then worked in Kent running a memory service, holding a position at KIMHS University of Kent and was the first clinical director at Kent and Medway NIHR Comprehensive Research Network. In 2010 he was appointed as the first Clinical Academic Psychiatrist at Norwich Medical School and Eastern region dementia DeNDRoN lead and he ended up head of department of clinical academic medicine until 2021.  
Chris has undertaken 4 highly cited Cochrane reviews in dementia, set up and developed clinical trials in dementia as a chief investigator and regional lead.

Chris has a long term UK/US collaboration with Indiana Medical School. He jointly co-developed work on the harms of screening, medication trials in dementia, collaborative care in dementia and the most highly cited anticholinergic burden scale. He  worked as an NHS consultant for 9 years and developed an applied research strategy.

Chris has led national programmes in hospital care research in dementia (PERFECTED/ASCRIBED) and has been a co-investigator on several large scale programmes of research in dementia over the last decade on technology (ATILLA), medication (MADE/SADD/Symbadd) and psychological interventions (PATHFINDER).

Chris currently leads 5 national NIHR programmes in sleep, dementia and multi-morbidity (TIMES), carers (CARECOACH), recovery colleges (DISCOVERY), social prescribing (SPLENDID) and AI diet risk modelling to prevent multimorbidity  (INFLAIM).

His key research themes are:

  • Data and multi-morbidity including applied artificial intelligence
  • Technology and healthcare
  • Novel medication CTIMPS relevant to dementia
  • Brain health - multi-morbidity

Chris is currently leading with 4 health care technology companies on multi-million pound research programmes in software/AI/ technical devices to improve delivery and assessment of health care.

Chris is co-medical director of NIHR Health Technology research centre south west and national industry engagement lead for the NIHR Health technology coordinating centre

Qualifications

  • MB BS
  • Bsc
  • Mmedsci
  • MD
  • MRCPsych
  • Cert AV Med

Career

Medical training 1985-1991

General medical 1991-1992

General practice Berlin Germany 1992-1993

Higher specialist training 1993-2001

Consultant psychiatrist/ Senior lecturer University of Kent/ Kent and medway NHS and social care partnership trust 2001-2010

Senior Lecturer->Professor of clinical psychiatry University of East Anglia 2010-2021

Honorary consultant psychiatrist Norfolk and suffolk nhs foundation trust 2010-

Professor of clinical psychiatry university of exeter 2021-

Links

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Research

Research interests

Professor Chris Fox has an interest in developing and evaluating interventions at scale in multi-morbidity and dementia using technology and novel data to support discovery and innovation.

Key flagship projects in intervention developments and data:

NIHR TIMES

MRC GEMINI (Led by Professor Frayling)

NIHR CARECOACH

NIHR SPLENDID

NIHR INFLAIM https://www.inflaim.com/the-team/

Biomedical research:

He has a track record in inflammation and its application in dementia. He leads the Alzheimers research UK ASCRIBED programme https://discovery.ucl.ac.uk/id/eprint/10082652/7/Zetterberg_Study%20protocol.%20ASCRIBED_VoR.pdf

ACB - pocast on Spotify

 https://open.spotify.com/episode/5RK4x5SoEfO2dRUzQOeqp9

Research projects

  • NIHR INFLAIM 2024-2032
  • NIHR SPLENDID 2023-2028 www.carecoachtimes.org/splendid
  • NIHR CARECOACH 2021-2026
  • NIHR DISCOVERY 2021-2024
  • NIHR TIMES 2022-2027
  • NIHR DISCOVERY 2022-2025
  • E-WHELD-2020-2022
  • PATHFINDER-2018-2023
  • MRC GEMINI 2021-2025
  • NIHR AIM INFLAIM 2020-2022
  • ARUK ASCRIBED 2017-2024

DiSCOVERY

Recovery in dementia: New study which will look at how NHS mental health Recovery Colleges may help to support people with dementia | Norfolk and Suffolk NHS (nsft.nhs.uk)

Rehabilitation in dementia video: https://youtu.be/gAM41EnEz0Q

Gemini MRC project: https://sites.exeter.ac.uk/gemini/

Research networks

NIHR ARC East of England

INTERDEM

DEMON

NIHR DEMENTIA PORTFOLIO RESEARCH GROUP

Member of national NIHR HRC managment group

Research grants

  • 2021 NIHR Health Services and Delivery Research
    Discovery - recovery colleges in dementia

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Publications

Journal articles

Allan LM (In Press). Is it possible to Develop a complex Intervention to improve the outcome of Fall-Related Injuries in people with Dementia? a mixed methods study to develop and assess the feasibility of the DIFRID intervention. Health Technology Assessment
McDermid J, Henley W, Corbett A, Williams G, Fossey J, Clare L, Fox C, Aarsland D, Khan Z, Soto M, et al (2024). Impact of the iWHELD digital person-centered care program on quality of life, agitation and psychotropic medications in people with dementia living in nursing homes during the COVID-19 pandemic: a randomized controlled trial. Alzheimers Dement, 20(3), 1797-1806. Abstract.  Author URL.
Marshall J, Papavasiliou E, Fox C, Hawkes M, Irvine A, Moniz-Cook E, Pick A, Polley MJ, Reeve J, Robinson L, et al (2024). Social prescribing for people living with dementia (PLWD) and their carers: what works, for whom, under what circumstances and why - protocol for a complex intervention systematic review. BMJ Open, 14(4). Abstract.  Author URL.
Banerjee S, Farina N, Henderson C, High J, Stirling S, Shepstone L, Fountain J, Ballard C, Bentham P, Burns A, et al (2023). A pragmatic, multicentre, double-blind, placebo-controlled randomised trial to assess the safety, clinical and cost-effectiveness of mirtazapine and carbamazepine in people with Alzheimer's disease and agitated behaviours: the HTA-SYMBAD trial. Health technology assessment (Winchester, England), 27(23), 1-108. Abstract.
Fox C, Hammond SP, Backhouse T, Poland F, Waring J, Penhale B, Cross JL (2023). Implementing PERFECT-ER with Plan-Do-Study-Act on acute orthopaedic hospital wards: Building knowledge from an implementation study using Normalization Process Theory. PLoS One, 18(2). Abstract.  Author URL.
Birt L, West J, Poland F, Wong G, Handley M, Litherland R, Hackmann C, Moniz-Cook E, Wolverson E, Teague B, et al (2023). Protocol for a realist evaluation of Recovery College dementia courses: understanding coproduction through ethnography. BMJ Open, 13(12).
Aryankhesal A, Blake J, Wong G, Megson M, Briscoe S, Allan L, Broomfield NM, Eastwood Z, Greene L, Hilton A, et al (2023). Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice. British Journal of General Practice, 74(741).
Logan PA, Horne JC, Allen F, Armstrong SJ, Clark AB, Conroy S, Darby J, Fox C, Gladman JR, Godfrey M, et al (2022). A multidomain decision support tool to prevent falls in older people: the FinCH cluster RCT. Health Technol Assess, 26(9), 1-136. Abstract.  Author URL.
Secchi A, Mamayusupova H, Sami S, Maidment I, Coulton S, Myint PK, Fox C (2022). A novel Artificial Intelligence-based tool to assess anticholinergic burden: a survey. Age Ageing, 51(8). Abstract.  Author URL.
Henderson C, Knapp M, Stirling S, Shepstone L, High J, Ballard C, Bentham P, Burns A, Farina N, Fox C, et al (2022). Cost-effectiveness of mirtazapine for agitated behaviors in dementia: findings from a randomized controlled trial. International Psychogeriatrics, 34(10), 905-917. Abstract.
Pontifex MG, Martinsen A, Saleh RNM, Harden G, Fox C, Muller M, Vauzour D, Minihane A-M (2022). DHA-Enriched Fish Oil Ameliorates Deficits in Cognition Associated with Menopause and the APOE4 Genotype in Rodents. Nutrients, 14(9).
Sanghavi R, Pana TA, Mamayusupova H, Maidment I, Fox C, Boekholdt SM, Mamas MA, Wareham NJ, Khaw K-T, Myint PK, et al (2022). Higher anticholinergic burden from medications is associated with significant increase in markers of inflammation in the EPIC-Norfolk prospective population-based cohort study. Br J Clin Pharmacol, 88(7), 3297-3306. Abstract.  Author URL.
Banerjee S, Jones C, Wright J, Grosvenor W, Hebditch M, Hughes L, Feeney Y, Farina N, Mackrell S, Nilforooshan R, et al (2021). A comparative study of the effect of the Time for Dementia programme on medical students. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 36(7), 1011-1019.  Author URL.
Moriarty F, Savva GM, Grossi CM, Bennett K, Fox C, Maidment I, Loke YK, Steel N, Kenny RA, Richardson K, et al (2021). Cognitive decline associated with anticholinergics, benzodiazepines and Z-drugs: Findings from the Irish Longitudinal Study on Ageing (TILDA). BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(7), 2818-2829.  Author URL.
Logan PA, Horne JC, Gladman JRF, Gordon AL, Sach T, Clark A, Robinson K, Armstrong S, Stirling S, Leighton P, et al (2021). Multifactorial falls prevention programme compared with usual care in UK care homes for older people: multicentre cluster randomised controlled trial with economic evaluation. BMJ, 375 Abstract.  Author URL.
Deane KHO, Jimoh OF, Biswas P, O'Brien A, Hanson S, Abdelhamid AS, Fox C, Hooper L (2021). Omega-3 and polyunsaturated fat for prevention of depression and anxiety symptoms: systematic review and meta-analysis of randomised trials. BRITISH JOURNAL OF PSYCHIATRY, 218(3), 135-142.  Author URL.
Lariviere M, Poland F, Woolham J, Newman S, Fox C (2021). Placing assistive technology and telecare in everyday practices of people with dementia and their caregivers: findings from an embedded ethnography of a national dementia trial. BMC GERIATRICS, 21(1).  Author URL.
Steyaert J, Deckers K, Smits C, Fox C, Thyrian R, Jeon Y-H, Vernooij-Dassen M, Kohler S (2021). Putting primary prevention of dementia on everybody's agenda. AGING & MENTAL HEALTH, 25(8), 1376-1380.  Author URL.
Howard R, Gathercole R, Bradley R, Harper E, Davis L, Pank L, Lam N, Talbot E, Hooper E, Winson R, et al (2021). The effectiveness and cost-effectiveness of assistive technology and telecare for independent living in dementia: a randomised controlled trial. Age Ageing, 50(3), 882-890. Abstract.  Author URL.
Pieper NT, Grossi CM, Chan W-Y, Loke YK, Savva GM, Haroulis C, Steel N, Fox C, Maidment ID, Arthur AJ, et al (2020). Anticholinergic drugs and incident dementia, mild cognitive impairment and cognitive decline: a meta-analysis. AGE AND AGEING, 49(6), 939-947.  Author URL.
Davison WJ, Myint PK, Loke YK, Ravenhill G, Turner D, Fox C, Shepstone L, Potter JF (2020). Can cardiovascular risk management be improved by shared care with general practice to prevent cognitive decline following stroke/TIA? a feasibility randomised controlled trial (SERVED memory). BMC GERIATRICS, 20(1).  Author URL.
Robinson K, Allen F, Darby J, Fox C, Gordon AL, Horne JC, Leighton P, Sims E, Logan PA (2020). Contamination in complex healthcare trials: the falls in care homes (FinCH) study experience. BMC Med Res Methodol, 20(1). Abstract.  Author URL.
Brayne CE, Barnes LE, Breteler MMB, Brooks RL, Dufouil C, Fox C, Fratiglioni L, Ikram MA, Kenny RA, Kivipelto M, et al (2020). Dementia Research Fit for the Planet: Reflections on Population Studies of Dementia for Researchers and Policy Makers Alike. NEUROEPIDEMIOLOGY, 54(2), 157-170.  Author URL.
Grossi CM, Richardson K, Savva GM, Fox C, Arthur A, Loke YK, Steel N, Brayne C, Matthews FE, Robinson L, et al (2020). Increasing prevalence of anticholinergic medication use in older people in England over 20 years: cognitive function and ageing study I and II. BMC GERIATRICS, 20(1).  Author URL.
Maidment ID, Barton G, Campbell N, Shaw R, Seare N, Fox C, Iliffe S, Randle E, Hilton A, Brown G, et al (2020). MEDREV (pharmacy-health psychology intervention in people living with dementia with behaviour that challenges): the feasibility of measuring clinical outcomes and costs of the intervention. BMC HEALTH SERVICES RESEARCH, 20(1).  Author URL.
Backhouse T, Hammond SP, Cross JL, Lambert N, Varley A, Penhale B, Fox C, Poland F (2020). Making body work sequences visible: an ethnographic study of acute orthopaedic hospital wards. SOCIOLOGY OF HEALTH & ILLNESS, 42(5), 1139-1154.  Author URL.
Howard R, Zubko O, Gray R, Bradley R, Harper E, Kelly L, Pank L, O’Brien J, Fox C, Tabet N, et al (2020). Minocycline 200 mg or 400 mg versus placebo for mild Alzheimer’s disease: the MADE Phase II, three-arm RCT. Abstract.
Richardson K, Wharton SB, Grossi CM, Matthews FE, Fox C, Maidment I, Loke YK, Steel N, Arthur A, Myint PK, et al (2020). Neuropathological Correlates of Cumulative Benzodiazepine and Anticholinergic Drug Use />. JOURNAL OF ALZHEIMERS DISEASE, 74(3), 999-1009.  Author URL.
Aldus CF, Arthur A, Dennington-Price A, Millac P, Richmond P, Dening T, Fox C, Matthews FE, Robinson L, Stephan BCM, et al (2020). Undiagnosed dementia in primary care: a record linkage study. Abstract.
Grossi CM, Richardson K, Fox C, Maidment I, Steel N, Loke YK, Arthur A, Myint PK, Campbell N, Boustani M, et al (2019). Anticholinergic and benzodiazepine medication use and risk of incident dementia: a UK cohort study. BMC GERIATRICS, 19(1).  Author URL.
Burn A-M, Bunn F, Fleming J, Turner D, Fox C, Malyon A, Brayne C (2019). Case finding for dementia during acute hospital admissions: a mixed-methods study exploring the impacts on patient care after discharge and costs for the English National Health Service. BMJ OPEN, 9(6).  Author URL.
Shenkin SD, Fox C, Godfrey M, Siddiqi N, Goodacre S, Young J, Anand A, Gray A, Hanley J, MacRaild A, et al (2019). Delirium detection in older acute medical inpatients: a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method. BMC Med, 17(1). Abstract.  Author URL.
Richardson K, Mattishent K, Loke YK, Steel N, Fox C, Grossi CM, Bennett K, Maidment I, Boustani M, Matthews FE, et al (2019). History of Benzodiazepine Prescriptions and Risk of Dementia: Possible Bias Due to Prevalent Users and Covariate Measurement Timing in a Nested Case-Control Study. AMERICAN JOURNAL OF EPIDEMIOLOGY, 188(7), 1228-1236.  Author URL.
MacLullich AM, Shenkin SD, Goodacre S, Godfrey M, Hanley J, Stíobhairt A, Lavender E, Boyd J, Stephen J, Weir C, et al (2019). The 4 'A's test for detecting delirium in acute medical patients: a diagnostic accuracy study. Health Technol Assess, 23(40), 1-194. Abstract.  Author URL.
Mattishent K, Richardson K, Dhatariya K, Savva GM, Fox C, Loke YK (2019). The effects of hypoglycaemia and dementia on cardiovascular events, falls and fractures and all-cause mortality in older individuals: a retrospective cohort study. DIABETES OBESITY & METABOLISM, 21(9), 2076-2085.  Author URL.
Boyd PJ, Nevard M, Ford JA, Khondoker M, Cross JL, Fox C (2019). The electronic frailty index as an indicator of community healthcare service utilisation in the older population. AGE AND AGEING, 48(2), 273-277.  Author URL.
Howard R, Cort E, Bradley R, Harper E, Kelly L, Bentham P, Ritchie C, Reeves S, Fawzi W, Livingston G, et al (2018). Amisulpride for very late-onset schizophrenia-like psychosis: the ATLAS three-arm RCT. HEALTH TECHNOLOGY ASSESSMENT, 22(67), 1-+.  Author URL.
Richardson K, Fox C, Maidment I, Steel N, Loke YK, Arthur A, Myint PK, Grossi CM, Mattishent K, Bennett K, et al (2018). Anticholinergic drugs and risk of dementia: case-control study. BMJ-BRITISH MEDICAL JOURNAL, 361  Author URL.
Howard R, Cort E, Bradley R, Harper E, Kelly L, Bentham P, Ritchie C, Reeves S, Fawzi W, Livingston G, et al (2018). Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS): a randomised, controlled, double-blind trial. LANCET PSYCHIATRY, 5(7), 553-563.  Author URL.
Burn A-M, Fleming J, Brayne C, Fox C, Bunn F (2018). Dementia case-finding in hospitals: a qualitative study exploring the views of healthcare professionals in English primary care and secondary care. BMJ OPEN, 8(3).  Author URL.
Smith T, Clark A, Dodd E, Khoo M-E, Heneker S, Cross J, Cheston R, Gray R, Fox C, Nolan F, et al (2018). Feasibility study suggests no impact from protected engagement time on adverse events in mental health wards for older adults. INTERNATIONAL JOURNAL OF MENTAL HEALTH NURSING, 27(2), 756-764.  Author URL.
Maidment ID, Damery S, Campbell N, Seare N, Fox C, Iliffe S, Hilton A, Brown G, Barnes N, Wilcock J, et al (2018). Medication review plus person-centred care: a feasibility study of a pharmacy-health psychology dual intervention to improve care for people living with dementia. BMC PSYCHIATRY, 18  Author URL.
Dodd E, Cheston R, Procter C, Heneker S, Gray R, Fox C, Nolan F (2018). Protected engagement time on older adult mental health wards: a thematic analysis of the views of patients, carers, and staff. INTERNATIONAL JOURNAL OF MENTAL HEALTH NURSING, 27(2), 608-618.  Author URL.
Smith T, Cross J, Poland F, Clay F, Brookes A, Maidment I, Penhale B, Laidlaw K, Fox C (2018). Systematic Review Investigating Multi-disciplinary Team Approaches to Screening and Early Diagnosis of Dementia in Primary Care - What are the Positive and Negative Effects and Who Should Deliver it?. CURRENT ALZHEIMER RESEARCH, 15(1), 5-17.  Author URL.
Maidment ID, Aston L, Moutela T, Fox CG, Hilton A (2017). A qualitative study exploring medication management in people with dementia living in the community and the potential role of the community pharmacist. HEALTH EXPECTATIONS, 20(5), 929-942.  Author URL.
Savulich G, Piercy T, Fox C, Suckling J, Rowe JB, O'Brien JT, Sahakian BJ (2017). Cognitive Training Using a Novel Memory Game on an iPad in Patients with Amnestic Mild Cognitive Impairment (aMCI). INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 20(8), 624-633.  Author URL.
Smith TO, Cooper A, Peryer G, Griffiths R, Fox C, Cross J (2017). Factors predicting incidence of post-operative delirium in older people following hip fracture surgery: a systematic review and meta-analysis. Int J Geriatr Psychiatry, 32(4), 386-396. Abstract.  Author URL.
Savulich G, Piercy T, Brühl AB, Fox C, Suckling J, Rowe JB, O'Brien JT, Sahakian BJ (2017). Focusing the Neuroscience and Societal Implications of Cognitive Enhancers. Clin Pharmacol Ther, 101(2), 170-172. Abstract.  Author URL.
Hammond SP, Cross JL, Poland FM, Patel M, Penhale B, Smith TO, Fox C (2017). Freedom of Information Act: scalpel or just a sharp knife?. JOURNAL OF MEDICAL ETHICS, 43(1), 60-62.  Author URL.
Coxon A, Nielsen K, Cross J, Fox C (2017). Implementing enhanced recovery pathways: a literature review with realist synthesis. Hosp Pract (1995), 45(4), 165-174. Abstract.  Author URL.
Gill N, Hammond S, Cross J, Smith T, Lambert N, Fox C (2017). Optimising care for patients with cognitive impairment and dementia following hip fracture. ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE, 50, S39-S43.  Author URL.
Myint PK, Loke YK, Davison W, Mattishent K, Fox GC, Fleetcroft R, Turner D, Shepstone L, Potter JF (2017). Protocol for a feasibility randomised controlled trial of Screening and Enhanced Risk management for Vascular Event-related Decline in Memory (SERVED Memory). BMJ open, 7(11). Abstract.
Nolan FM, Fox C, Cheston R, Turner D, Clark A, Dodd E, Khoo M-E, Gray R (2016). A feasibility study comparing UK older adult mental health inpatient wards which use protected engagement time with other wards which do not: study protocol. Pilot Feasibility Stud, 2 Abstract.  Author URL.
Abdelhamid A, Bunn D, Copley M, Cowap V, Dickinson A, Gray L, Howe A, Killett A, Lee J, Li F, et al (2016). Effectiveness of interventions to directly support food and drink intake in people with dementia: systematic review and meta-analysis. BMC Geriatr, 16 Abstract.  Author URL.
Bunn DK, Abdelhamid A, Copley M, Cowap V, Dickinson A, Howe A, Killett A, Poland F, Potter JF, Richardson K, et al (2016). Effectiveness of interventions to indirectly support food and drink intake in people with dementia: Eating and Drinking Well IN dementiA (EDWINA) systematic review. BMC GERIATRICS, 16  Author URL.
Maidment ID, Shaw RL, Killick K, Damery S, Hilton A, Wilcock J, Barnes N, Brown G, Gillespie S, Fox C, et al (2016). Improving the management of behaviour that challenges associated with dementia in care homes: protocol for pharmacy-health psychology intervention feasibility study. BMJ OPEN, 6(3).  Author URL.
Woehrling EK, Parri HR, Tse EHY, Hill EJ, Maidment ID, Fox GC, Coleman MD (2015). A predictive in vitro model of the impact of drugs with anticholinergic properties on human neuronal and astrocytic systems. PloS one, 10(3). Abstract.
Martin S, Kelly S, Khan A, Cullum S, Dening T, Rait G, Fox C, Katona C, Cosco T, Brayne C, et al (2015). Attitudes and preferences towards screening for dementia: a systematic review of the literature. BMC GERIATRICS, 15  Author URL.
Sakel M, Boukouvalas A, Buono R, Moten M, Mirza F, Chan W-Y, Maidment I, Cross J, Smith TO, Myint PK, et al (2015). Does anticholinergics drug burden relate to global neuro-disability outcome measures and length of hospital stay?. Brain Inj, 29(12), 1426-1430. Abstract.  Author URL.
Smith TO, Hameed YA, Cross JL, Henderson C, Sahota O, Fox C (2015). Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery. COCHRANE DATABASE OF SYSTEMATIC REVIEWS(6).  Author URL.
Martin S, Fleming J, Cullum S, Dening T, Rait G, Fox C, Katona C, Brayne C, Lafortune L (2015). Exploring attitudes and preferences for dementia screening in Britain: contributions from carers and the general public. BMC GERIATRICS, 15  Author URL.
Teipel S, Drzezga A, Grothe MJ, Barthel H, Chetelat G, Schuff N, Skudlarski P, Cavedo E, Frisoni GB, Hoffmann W, et al (2015). Multimodal imaging in Alzheimer's disease: validity and usefulness for early detection. LANCET NEUROLOGY, 14(10), 1037-1053.  Author URL.
Myint PK, Fox C, Kwok CS, Luben RN, Wareham NJ, Khaw K-T (2015). Total anticholinergic burden and risk of mortality and cardiovascular disease over 10 years in 21,636 middle-aged and older men and women of EPIC-Norfolk prospective population study. AGE AND AGEING, 44(2), 219-225.  Author URL.
Richardson K, Bennett K, Maidment ID, Fox C, Smithard D, Kenny RA (2015). Use of Medications with Anticholinergic Activity and Self-Reported Injurious Falls in Older Community-Dwelling Adults. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 63(8), 1561-1569.  Author URL.
Dodd E, Cheston R, Fear T, Brown E, Fox C, Morley C, Jefferies R, Gray R (2014). An evaluation of primary care led dementia diagnostic services in Bristol. BMC HEALTH SERVICES RESEARCH, 14  Author URL.
Underwood BR, Fox C (2014). Citalopram decreases agitation in the context of Alzheimer's disease, but at doses higher than those commonly prescribed and at the expense of side effects. Evid Based Med, 19(5).  Author URL.
Ebert TJ, Fox CA (2014). Competency-based Education in Anesthesiology <i>History and Challenges</i>. ANESTHESIOLOGY, 120(1), 24-31.  Author URL.
Fox C, Smith T, Maidment I, Chan W-Y, Bua N, Myint PK, Boustani M, Kwok CS, Glover M, Koopmans I, et al (2014). Effect of medications with anti-cholinergic properties on cognitive function, delirium, physical function and mortality: a systematic review. AGE AND AGEING, 43(5), 604-615.  Author URL.
Iliffe S, Robinson L, Bamford C, Waugh A, Fox C, Livingston G, Manthorpe J, Brown P, Stephens B, Brittain K, et al (2014). Introducing case management for people with dementia in primary care: a mixed-methods study. BRITISH JOURNAL OF GENERAL PRACTICE, 64(628), E735-E741.  Author URL.
Brownlie K, Schneider C, Culliford R, Fox C, Boukouvalas A, Willan C, Maidment ID (2014). Medication reconciliation by a pharmacy technician in a mental health assessment unit. INTERNATIONAL JOURNAL OF CLINICAL PHARMACY, 36(2), 303-309.  Author URL.
Poland F, Mapes S, Pinnock H, Katona C, Sorensen S, Fox C, Maidment ID (2014). Perspectives of carers on medication management in dementia: lessons from collaboratively developing a research proposal. BMC Res Notes, 7 Abstract.  Author URL.
Smith T, Maidment I, Hebding J, Madzima T, Cheater F, Cross J, Poland F, White J, Young J, Fox C, et al (2014). Systematic review investigating the reporting of comorbidities and medication in randomized controlled trials of people with dementia. AGE AND AGEING, 43(6), 868-872.  Author URL.
Iliffe S, Waugh A, Poole M, Bamford C, Brittain K, Chew-Graham C, Fox C, Katona C, Livingston G, Manthorpe J, et al (2014). The effectiveness of collaborative care for people with memory problems in primary care: results of the CAREDEM case management modelling and feasibility study. Health Technol Assess, 18(52), 1-148. Abstract.  Author URL.
Fox C, Smith T, Maidment I, Hebding J, Madzima T, Cheater F, Cross J, Poland F, White J, Young J, et al (2014). The importance of detecting and managing comorbidities in people with dementia?. AGE AND AGEING, 43(6), 741-743.  Author URL.
Fox C, Alessi C, Ahluwalia S, Hachinski V (2014). The use of wide-scale mental agility testing to identify people at risk of dementia: crucial or harmful?. J R Coll Physicians Edinb, 44(1), 30-35. Abstract.  Author URL.
Bamford C, Poole M, Brittain K, Chew-Graham C, Fox C, Iliffe S, Manthorpe J, Robinson L, CAREDEM team (2014). Understanding the challenges to implementing case management for people with dementia in primary care in England: a qualitative study using Normalization Process Theory. BMC Health Serv Res, 14 Abstract.  Author URL.
Smith T, Hameed Y, Cross J, Sahota O, Fox C (2013). Assessment of people with cognitive impairment and hip fracture: a systematic review and meta-analysis. ARCHIVES OF GERONTOLOGY AND GERIATRICS, 57(2), 117-126.  Author URL.
Fox C (2013). Beyond software: foundations for advanced labor management. Health Manag Technol, 34(10).  Author URL.
Fox C (2013). Consolidating healthcare. Health Manag Technol, 34(4), 14-15.  Author URL.
Waugh A, Austin A, Manthorpe J, Fox C, Stephens B, Robinson L, Iliffe S (2013). Designing a complex intervention for dementia case management in primary care. BMC FAMILY PRACTICE, 14  Author URL.
Kok D, Gill S, Bressel M, Byrne K, Kron T, Fox C, Duchesne G, Tai KH, Foroudi F (2013). Late toxicity and biochemical control in with and without dose escalated image 554 prostate cancer patients treated guided radiotherapy. RADIOTHERAPY AND ONCOLOGY, 107(2), 140-146.  Author URL.
Fox C, Maidment I, Moniz-Cook E, White J, Thyrian JR, Young J, Katona C, Chew-Graham CA (2013). Optimising primary care for people with dementia. Ment Health Fam Med, 10(3), 143-151. Abstract.  Author URL.
Tan J, Heriot AG, Mackay J, Van Dyk S, Bressel MAB, Fox CD, Hui AC, Lynch AC, Leong T, Ngan SY, et al (2013). Prospective single-arm study of intraoperative radiotherapy for locally advanced or recurrent rectal cancer. JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, 57(5), 617-625.  Author URL.
Fox C, Lafortune L, Boustani M, Dening T, Rait G, Brayne C (2013). Screening for dementia--is it a no brainer?. Int J Clin Pract, 67(11), 1076-1080. Abstract.  Author URL.
Fox C, Lafortune L, Boustani M, Brayne C (2013). The pros and cons of early diagnosis in dementia. BRITISH JOURNAL OF GENERAL PRACTICE, 63(612), E510-E512.  Author URL.
Child A, Clarke A, Fox C, Maidment I (2012). A pharmacy led program to review anti-psychotic prescribing for people with dementia. BMC PSYCHIATRY, 12  Author URL.
Rolinski M, Fox C, Maidment I, McShane R (2012). Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease. COCHRANE DATABASE OF SYSTEMATIC REVIEWS(3).  Author URL.
Khan BA, Zawahiri M, Campbell NL, Fox GC, Weinstein EJ, Nazir A, Farber MO, Buckley JD, Maclullich A, Boustani MA, et al (2012). Delirium in hospitalized patients: implications of current evidence on clinical practice and future avenues for research--a systematic evidence review. Journal of hospital medicine, 7(7), 580-589. Abstract.
Maidment ID, Fox C, Boustani M, Katona C (2012). Medication managementuthe missing link in dementia interventions. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 27(5), 439-442.  Author URL.
Koch T, Iliffe S, Manthorpe J, Stephens B, Fox C, Robinson L, Livingston G, Coulton S, Knapp M, Chew-Graham C, et al (2012). The potential of case management for people with dementia: a commentary. Int J Geriatr Psychiatry, 27(12), 1305-1314. Abstract.  Author URL.
Gill S, Thomas J, Fox C, Kron T, Rolfo A, Leahy M, Chander S, Williams S, Tai KH, Duchesne GM, et al (2011). Acute toxicity in prostate cancer patients treated with and without image-guided radiotherapy. RADIATION ONCOLOGY, 6  Author URL.
Fox C, Richardson K, Maidment ID, Savva GM, Matthews FE, Smithard D, Coulton S, Katona C, Boustani MA, Brayne C, et al (2011). Anticholinergic Medication Use and Cognitive Impairment in the Older Population: the Medical Research Council Cognitive Function and Ageing Study. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 59(8), 1477-1483.  Author URL.
Fox C, Livingston G, Maidment ID, Coulton S, Smithard DG, Boustani M, Katona C (2011). The impact of anticholinergic burden in Alzheimer's Dementia-the Laser-AD study. AGE AND AGEING, 40(6), 730-735.  Author URL.
Treloar A, Crugel M, Prasanna A, Solomons L, Fox C, Paton C, Katona C (2010). Ethical dilemmas: should antipsychotics ever be prescribed for people with dementia?. BRITISH JOURNAL OF PSYCHIATRY, 197(2), 88-90.  Author URL.
Fox C (2010). Evidence summary: what do we know from qualitative research about people's care-seeking about oral health?. BRITISH DENTAL JOURNAL, 209(5), 225-231.  Author URL.
Kron T, Thomas J, Fox C, Thompson A, Owen R, Herschtal A, Haworth A, Tai K-H, Foroudi F (2010). Intra-fraction prostate displacement in radiotherapy estimated from pre- and post-treatment imaging of patients with implanted fiducial markers. RADIOTHERAPY AND ONCOLOGY, 95(2), 191-197.  Author URL.
Shotbolt P, Samuel M, Fox C, David AS (2009). A randomized controlled trial of quetiapine for psychosis in Parkinson's disease. NEUROPSYCHIATRIC DISEASE AND TREATMENT, 5, 327-332.  Author URL.
Justiss MD, Boustani M, Fox C, Katona C, Perkins AJ, Healey PJ, Sach G, Hui S, Callahan CM, Hendrie HC, et al (2009). Patients' attitudes of dementia screening across the Atlantic. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 24(6), 632-637.  Author URL.
Campbell N, Boustani MA, Ayub A, Fox GC, Munger SL, Ott C, Guzman O, Farber M, Ademuyiwa A, Singh R, et al (2009). Pharmacological management of delirium in hospitalized adults--a systematic evidence review. Journal of general internal medicine, 24(7), 848-853. Abstract.
Herschtal A, Kron T, Fox C (2009). Radiotherapy margin design with particular consideration of high curvature CTVs. MEDICAL PHYSICS, 36(3), 684-697.  Author URL.
Campbell N, Boustani M, Limbil T, Ott C, Fox C, Maidment I, Schubert CC, Munger S, Fick D, Miller D, et al (2009). The cognitive impact of anticholinergics: a clinical review. CLINICAL INTERVENTIONS IN AGING, 4, 225-233.  Author URL.
Campbell N, Ayub A, Boustani MA, Fox C, Farlow M, Maidment I, Howard R (2008). Impact of cholinesterase inhibitors on behavioral and psychological symptoms of Alzheimer's disease: a meta-analysis. CLINICAL INTERVENTIONS IN AGING, 3(4), 719-728.  Author URL.
Boustani M, Perkins AJ, Monahan P, Fox C, Watson L, Hopkins J, Fultz B, Hui S, Unverzagt FW, Callahan CM, et al (2008). Measuring primary care patients' attitudes about dementia screening. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 23(8), 812-820.  Author URL.
Maidment ID, Haw C, Stubbs J, Fox C, Katona C, Franklin BD (2008). Medication errors in older people with mental health problems: a review. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 23(6), 564-573.  Author URL.
Joshi D, Vosough A, Raymond TM, Fox C, Dhiman A (2007). Bouveret's syndrome as an unusual cause of gastric outlet obstruction: a case report. J Med Case Rep, 1 Abstract.  Author URL.
Brayne C, Fox C, Boustani M (2007). Dementia screening in primary care - is it time?. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 298(20), 2409-2411.  Author URL.
Maidment I, Fox C, Boustani M (2006). Cholinesterase inhibitors for Parkinson's disease dementia. Cochrane Database Syst Rev(1). Abstract.  Author URL.
Schubert CC, Boustani M, Callahan CM, Perkins AJ, Carney CP, Fox C, Unverzagt F, Hui S, Hendrie HC (2006). Comorbidity profile of dementia patients in primary care: Are they sicker?. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 54(1), 104-109.  Author URL.
Maidment I, Fox C, Livingston G, Katona C (2006). Drug treatment for Alzheimer's disease: the way forward. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 21(1), 6-8.  Author URL.
Fox C, Maidment ID, Boustani M, Katona C (2006). Memantine combined with an acetyl cholinesterase inhibitor - hope for the future?. Neuropsychiatr Dis Treat, 2(2), 121-125. Abstract.  Author URL.
Boustani M, Perkins AJ, Fox C, Unverzagt F, Austrom MG, Fultz B, Hui S, Callahan CM, Hendrie HC (2006). Who refuses the diagnostic assessment for dementia in primary care?. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 21(6), 556-563.  Author URL.
Maidment ID, Fox C, Boustani M (2005). A review of studies describing the use of acetyl cholinesterase inhibitors in Parkinson's disease dementia. Acta Psychiatr Scand, 111(6), 403-409. Abstract.  Author URL.
Metcalfe P, Chapman A, Arnold A, Arnold B, Tangboonduangjit P, Capp A, Fox C (2004). Intensity-modulated radiation therapy: not a dry eye in the house. Australas Radiol, 48(1), 35-44. Abstract.  Author URL.
Edwards C, Fox C (2001). Quality of care for people with dementia. Dementia care mapping is inadequate tool for research. BMJ, 323(7326), 1427-1428.  Author URL.
Fox C, Edwards C, Rennick S (2000). Behavioural difficulties. Int J Geriatr Psychiatry, 15(5), 467-468.  Author URL.
Duffy P, Fox C, Reid G (1999). Post-traumatic stress disorder. J R Soc Med, 92(3).  Author URL.
Neal LA, Shapland W, Fox C (1997). An open trial of moclobemide in the treatment of post-traumatic stress disorder. Int Clin Psychopharmacol, 12(4), 231-237. Abstract.  Author URL.
Neal LA, Fox C, Carroll N, Holden M, Barnes P (1997). Development and validation of a computerized screening test for personality disorders in DSM-III-R. Acta Psychiatr Scand, 95(4), 351-356. Abstract.  Author URL.

Conferences

Maidment ID, Fox CG, Boustani M, Rodriguez J, Brown RC, Katona CL (2008). Efficacy of memantine on behavioral and psychological symptoms related to dementia: a systematic meta-analysis.  Author URL.

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External Engagement and Impact

Awards

  • Max Hamilton Prize for psychiatry research 1999 University of Leeds
  • Altman bursary 1999 for stats University of Oxford
  • Presidential Award for best clinical trial “MAGD trial” 2011 AGS USA

Committee/panel activities

  • Chair of NIHR Dementia national portfolio development group.
  • Editor Geriatrics
  • Board member Interdem dementia public health, prevention and technology
  • Board member NIHR ARC eastern data and multimorbidity themes
  • Clinical Advisor to Alzheimer’s Research UK policy group
  • Board member Costal Health NIHR ARC Network
  • Co-director NIHR HRC sustainable technology

Invited lectures

  • Interdem academy Nottingham October 2021
  • Dementia 2022 conference
  • MSNAP conference 2023 key note

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Teaching

Teaching responsibilities: (Undergraduate, Postgraduate)

Advisee tutor Norwich Medical School

Phd Supervisor

External Examiner:

Dementia MSC University of Brighton

Neurodegeneraton DPHil University of Cambridge

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