COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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Dr Byron Creese

Dr Byron Creese

Senior Lecturer in Neuroscience

 RILD Building Level 4

 

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Overview

My work focuses on understanding the biology, clinical consequences and treatment of neuropsychiatric symptoms (e.g. hallucinations, suspicious thoughts, depression) occurring in later life and dementia.  I have led some of the UK's first work into Mild Behavioural Impairment, a novel framework which describes a spectrum of neuropscyhiatric symptoms which may, for some, be the very first noticable sign of neurodegenerative disease.  I am also involved in major projects aiming to understand the biology of psychotic symptoms in Alzheimer's disease and other dementias.

Research group links

Research

Research interests

  • Psychosis and other neuropsychiatric symptoms in dementia, including biological mechanisms and treatments.
  • Neuropsychiatric symptoms as early indicators of neurodgenerative disease (known as Mild Behavioural Impairment)

Research projects

PROTECT study (https://www.protectstudy.org.uk/) in UK and Canada (online studies into cognitive ageing).

A multi-omic approach to elucidating disease mechanisms of psychosis in Alzheimer’s disease. 

Elucidating the role of DNA methylation in the pathophysiology of lewy body diseases.

Research grants

  • 2019 National Institutes of Health
    A multi-omic approach to elucidating disease mechanisms of psychosis in Alzheimer’s disease
  • 2019 ARUK South West Network
    An examination of the neuropsychological mechanisms underpinning delusional thoughts in older adults at risk of dementia
  • 2019 ISSF Wellcome Trust Seed Corn Fund
    A preclinical drug screening protocol for the detection of off-target activity of psychotropic drugs for the treatment of neuropsychiatric symptoms in Alzheimer’s disease
  • 2019 MRC
    Elucidating the role of DNA methylation in the pathophysiology of lewy body diseases
  • 2018 MRC Proximity to Discovery
    Identifying genetic and clinical markers of cognitive decline in healthy adults
  • 2018 MRC Proximity to Discovery
    Mechanisms of therapeutic benefit and harm underpinning compounds used for treatment of neuropsychiatric symptoms in Alzheimer’s disease
  • 2018 ARUK South West Network
    Feasibility study of a proxy phenotype of psychotic symptoms in Alzheimer’s disease

Publications

Key publications | Publications by category | Publications by year

Key publications


Creese B, Arathimos R, Brooker H, Aarsland D, Corbett A, Lewis C, Ballard C, Ismail Z (In Press). Genetic risk for Alzheimer’s disease, cognition and Mild Behavioral Impairment in healthy older adults. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring Full text.
Creese B, Khan Z, Henley W, O'Dwyer S, Corbett A, Vasconcelos Da Silva M, Mills K, Wright N, Testad I, Aarsland D, et al (In Press). Loneliness, physical activity and mental health during Covid-19: a longitudinal analysis of depression and anxiety in adults over 50 between 2015 and 2020. International Psychogeriatrics Full text.
Creese BA, Brooker H, Ismail Z, Wesnes K, Adam H, Khan Z, Maria M, Corbett A, Aarsland D, Ballard C, et al (In Press). Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults. American Journal of Geriatric Psychiatry Full text.
Pishva SE, Creese B, Smith A, Ballard C, Mill J, Lunnon K (In Press). Psychosis-associated DNA methylomic variation in Alzheimer’s disease cortex. Neurobiology of Aging Full text.
Creese B, Ballard C (In Press). Revisiting criteria for psychosis in Alzheimer’s disease and related dementias- towards better phenotypic classification and biomarker research. Journal of Alzheimer's Disease Full text.
Malekizadeh Y, Williams G, Kelson M, Whitfield D, Mill J, Collier D, Ballard C, Jeffries A, Creese B (In Press). Whole transcriptome in-silico screening implicates cardiovascular and infectious disease in the mechanism of action underlying atypical antipsychotic side-effects. Alzheimer's and Dementia: Translational Research and Clinical Interventions Full text.

Publications by category


Journal articles

Smith S, Griffiths AW, Creese B, Sass C, Surr C (In Press). A biopsychosocial interpretation of the Neuropsychiatric Inventory-Nursing Home (NH): reconceptualising psychiatric symptom attributions. BJPsych Open Full text.
Creese B, Vassos E, Bergh S, Athanasiu L, Johar I, Rongve A, Medbøen IT, Da Silva MV, Aakhus E, Andersen F, et al (In Press). Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer’s disease: meta-analysis of 11 cohort studies.  Abstract.
Creese B, Ballard C (In Press). Cost-effectiveness of Dementia Care Mapping in care home settings – Evaluation of a randomised controlled trial. Applied Health Economics and Health Policy Full text.
Surr C, Holloway I, Walwyn REA, Grifiths AW, Meads D, Martin A, Kelley R, Ballard C, Fossey J, Burnley N, et al (In Press). Effectiveness of Dementia Care Mapping™ to reduce agitation in care home residents with dementia: an open-cohort cluster randomised controlled trial. Aging and Mental Health Full text.
Ballard C, Brooker H, Corbett A, Ismail Z, Creese B, Wesnes K (In Press). FLAME: a computerized neuropsychological composite for trials in early dementia. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring Full text.
Creese B, Arathimos R, Brooker H, Aarsland D, Corbett A, Lewis C, Ballard C, Ismail Z (In Press). Genetic risk for Alzheimer’s disease, cognition and Mild Behavioral Impairment in healthy older adults. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring Full text.
DeMichele-Sweet MAA, Klei L, Creese B, Harwood JC, Weamer EA, McClain L, Sims R, Hernandez I, Moreno-Grau S, Tárraga L, et al (In Press). Genome-Wide Association Identifies the First Risk Loci for Psychosis in Alzheimer Disease.  Abstract.
Ballard C, Creese B, Gatt A, Doherty P, Francis PT, Whitfield D, Corbett A, Corcoran J, Hanger D, Thuret S, et al (In Press). Identifying Novel Candidates for Re-Purposing as Potential Therapeutic Agents for Alzheimer’s disease.  Abstract.
Creese B, Khan Z, Henley W, O'Dwyer S, Corbett A, Vasconcelos Da Silva M, Mills K, Wright N, Testad I, Aarsland D, et al (In Press). Loneliness, physical activity and mental health during Covid-19: a longitudinal analysis of depression and anxiety in adults over 50 between 2015 and 2020. International Psychogeriatrics Full text.
Creese BA, Brooker H, Ismail Z, Wesnes K, Adam H, Khan Z, Maria M, Corbett A, Aarsland D, Ballard C, et al (In Press). Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults. American Journal of Geriatric Psychiatry Full text.
Daunt P, Ballard C, Creese B, Davidson G, Hardy J, Oshota O, Pither RJ, Gibson AM (In Press). Polygenic Risk Scoring is an Effective Approach to Predict Those Individuals Most Likely to Decline Cognitively Due to Alzheimer’s Disease. The journal of prevention of Alzheimer's disease Full text.
Pishva SE, Creese B, Smith A, Ballard C, Mill J, Lunnon K (In Press). Psychosis-associated DNA methylomic variation in Alzheimer’s disease cortex. Neurobiology of Aging Full text.
Creese B, Ballard C (In Press). Revisiting criteria for psychosis in Alzheimer’s disease and related dementias- towards better phenotypic classification and biomarker research. Journal of Alzheimer's Disease Full text.
Creese B, Corbett A, Ballard C (In Press). The mental and physical health of older adults with a genetic predisposition for autism. Autism Research: official journal of the International Society for Autism Research Full text.
Griffiths A, Albertyn C, Burnley N, Creese BA, Walwyn R, Holloway I, Safarikova J, Surr C (In Press). Validation of the Cohen-Mansfield Agitation Inventory Observational (CMAI-O) Tool. International Psychogeriatrics Full text.
Malekizadeh Y, Williams G, Kelson M, Whitfield D, Mill J, Collier D, Ballard C, Jeffries A, Creese B (In Press). Whole transcriptome in-silico screening implicates cardiovascular and infectious disease in the mechanism of action underlying atypical antipsychotic side-effects. Alzheimer's and Dementia: Translational Research and Clinical Interventions Full text.
DeMichele-Sweet MAA, Klei L, Creese B, Harwood JC, Weamer EA, McClain L, Sims R, Hernandez I, Moreno-Grau S, Tárraga L, et al (2021). Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease. Molecular Psychiatry
Surr CA, Holloway I, Walwyn RE, Griffiths AW, Meads D, Kelley R, Martin A, McLellan V, Ballard C, Fossey J, et al (2020). Dementia Care Mapping™ to reduce agitation in care home residents with dementia: the EPIC cluster RCT. Health Technol Assess, 24(16), 1-172. Abstract.  Author URL.  Full text.
Creese B, Albertyn CP, Dworkin S, Thomas RS, Wan YM, Ballard C (2020). Executive function but not episodic memory decline associated with visual hallucinations in Parkinson's disease. J Neuropsychol, 14(1), 85-97. Abstract.  Author URL.  Full text.
Ballard C, Kales HC, Lyketsos C, Aarsland D, Creese B, Mills R, Williams H, Sweet RA (2020). Psychosis in Alzheimer's Disease. Curr Neurol Neurosci Rep, 20(12). Abstract.  Author URL.  Full text.
Stewart GR, Corbett A, Ballard C, Creese B, Aarsland D, Hampshire A, Charlton RA, Happé F (2020). Sleep problems and mental health difficulties in older adults who endorse high autistic traits. Research in Autism Spectrum Disorders, 77 Abstract.  Full text.
Stewart GR, Corbett A, Ballard C, Creese B, Aarsland D, Hampshire A, Charlton RA, Happé F (2020). The mental and physical health profiles of older adults who endorse elevated autistic traits. J Gerontol B Psychol Sci Soc Sci Abstract.  Author URL.  Full text.
Creese B, Ballard C, Vasconcelos Da Silva M (2019). Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer’s disease. Translational Psychiatry Full text.
Creese BA, Griffiths A, Brooker H, Corbett A, Aarsland D, Ballard C, Ismail Z (2019). Profile of Mild Behavioral Impairment and Factor Structure of the Mild Behavioral Impairment Checklist in Cognitively Normal Older Adults. International Psychogeriatrics Full text.
Griffiths AW, Surr CA, Creese B, Garrod L, Chenoweth L (2019). The development and use of the assessment of dementia awareness and person-centred care training tool in long-term care. Dementia (London), 18(7-8), 3059-3070. Author URL.  Full text.
Griffiths AW, Albertyn CP, Burnley NL, Creese B, Walwyn R, Holloway I, Safarikova J, Surr CA (2019). Validation of the Cohen-Mansfield Agitation Inventory Observational (CMAI-O) tool - ERRATUM. International Psychogeriatrics, 32(2), 287-287. Abstract.
Nunez KM, Khan Z, Testad I, Lawrence V, Creese B, Corbett A (2018). Current practice and challenges in night-time care for people with dementia living in care homes: a qualitative study. Int J Geriatr Psychiatry, 33(1), e140-e149. Abstract.  Author URL.
Creese B, Bell E, Johar I, Francis P, Ballard C, Aarsland D (2018). Glucocerebrosidase mutations and neuropsychiatric phenotypes in Parkinson's disease and Lewy body dementias: Review and meta-analyses. Am J Med Genet B Neuropsychiatr Genet, 177(2), 232-241. Abstract.  Author URL.  Full text.
Creese B, Da Silva MV, Johar I, Ballard C (2018). The modern role of antipsychotics for the treatment of agitation and psychosis in Alzheimer's disease. Expert Rev Neurother, 18(6), 461-467. Abstract.  Author URL.  Full text.
Aarsland D, Creese B, Chaudhuri KR (2017). A new tool to identify patients with Parkinson's disease at increased risk of dementia. Lancet Neurol, 16(8), 576-578. Author URL.
Aarsland D, Creese B, Politis M, Chaudhuri KR, Ffytche DH, Weintraub D, Ballard C (2017). Cognitive decline in Parkinson disease. Nat Rev Neurol, 13(4), 217-231. Abstract.  Author URL.  Full text.
Ffytche DH, Creese B, Politis M, Chaudhuri KR, Weintraub D, Ballard C, Aarsland D (2017). The psychosis spectrum in Parkinson disease. Nat Rev Neurol, 13(2), 81-95. Abstract.  Author URL.  Full text.
Surr CA, Walwyn REA, Lilley-Kelly A, Cicero R, Meads D, Ballard C, Burton K, Chenoweth L, Corbett A, Creese B, et al (2016). Evaluating the effectiveness and cost-effectiveness of Dementia Care Mapping™ to enable person-centred care for people with dementia and their carers (DCM-EPIC) in care homes: study protocol for a randomised controlled trial. Trials, 17(1). Abstract.  Author URL.  Full text.
Ballard C, Thomas A, Gerry S, Yu L-M, Aarsland D, Merritt C, Corbett A, Davison C, Sharma N, Khan Z, et al (2015). A Double-Blind Randomized Placebo-Controlled Withdrawal Trial Comparing Memantine and Antipsychotics for the Long-Term Treatment of Function and Neuropsychiatric Symptoms in People with Alzheimer's Disease (MAIN-AD). JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 16(4), 316-322. Author URL.
Creese B, Ballard C, Aarsland D, Londos E, Sharp S, Jones E (2014). Determining the Association of the 5HTTLPR Polymorphism with Delusions and Hallucinations in Lewy Body Dementias. The American Journal of Geriatric Psychiatry, 22(6), 580-586.
Creese B, Corbett A, Jones E, Fox C, Ballard C (2014). Role of the Extended MAPT Haplotype in the Worsening of Psychotic Symptoms and Treatment Response in Alzheimer Disease. Journal of the American Medical Directors Association, 15(12), 934-937.
Creese B, Ballard C, Jones E (2013). Cognitive Impairment in Studies of 5HTTLPR and Psychosis in Alzheimer’s Disease: a Systematic Review. Dementia and Geriatric Cognitive Disorders, 35(3-4), 155-164.
Creese B, Ballard C, Aarsland D, Londos E, Sharp S, Jones E (2012). No association of COMT val158met polymorphism and psychotic symptoms in Lewy body dementias. Neuroscience Letters, 531(1), 1-4.
Corbett A, Smith J, Creese B, Ballard C (2012). Treatment of Behavioral and Psychological Symptoms of Alzheimer’s Disease. Current Treatment Options in Neurology, 14(2), 113-125.
Creese B, Ballard C, Corbett A, Aarsland D (2011). Atypical antipsychotics for the treatment of behavioral and psychological symptoms in dementia, with a particular focus on longer term outcomes and mortality. Expert Opinion on Drug Safety, 10, 35-43.

Chapters

Corbett A, Ballard C, Creese BA (2018). Evidence-based management of behavioural and psychological symptoms of dementia. In Michel J-P, Beattie BL, Martin FC, Walston JD (Eds.) Oxford Textbook of Geriatric Medicine, Oxford University Press, 1015-1020.  Abstract.

Publications by year


In Press

Smith S, Griffiths AW, Creese B, Sass C, Surr C (In Press). A biopsychosocial interpretation of the Neuropsychiatric Inventory-Nursing Home (NH): reconceptualising psychiatric symptom attributions. BJPsych Open Full text.
Creese B, Vassos E, Bergh S, Athanasiu L, Johar I, Rongve A, Medbøen IT, Da Silva MV, Aakhus E, Andersen F, et al (In Press). Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer’s disease: meta-analysis of 11 cohort studies.  Abstract.
Creese B, Ballard C (In Press). Cost-effectiveness of Dementia Care Mapping in care home settings – Evaluation of a randomised controlled trial. Applied Health Economics and Health Policy Full text.
Surr C, Holloway I, Walwyn REA, Grifiths AW, Meads D, Martin A, Kelley R, Ballard C, Fossey J, Burnley N, et al (In Press). Effectiveness of Dementia Care Mapping™ to reduce agitation in care home residents with dementia: an open-cohort cluster randomised controlled trial. Aging and Mental Health Full text.
Ballard C, Brooker H, Corbett A, Ismail Z, Creese B, Wesnes K (In Press). FLAME: a computerized neuropsychological composite for trials in early dementia. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring Full text.
Creese B, Arathimos R, Brooker H, Aarsland D, Corbett A, Lewis C, Ballard C, Ismail Z (In Press). Genetic risk for Alzheimer’s disease, cognition and Mild Behavioral Impairment in healthy older adults. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring Full text.
DeMichele-Sweet MAA, Klei L, Creese B, Harwood JC, Weamer EA, McClain L, Sims R, Hernandez I, Moreno-Grau S, Tárraga L, et al (In Press). Genome-Wide Association Identifies the First Risk Loci for Psychosis in Alzheimer Disease.  Abstract.
Ballard C, Creese B, Gatt A, Doherty P, Francis PT, Whitfield D, Corbett A, Corcoran J, Hanger D, Thuret S, et al (In Press). Identifying Novel Candidates for Re-Purposing as Potential Therapeutic Agents for Alzheimer’s disease.  Abstract.
Creese B, Khan Z, Henley W, O'Dwyer S, Corbett A, Vasconcelos Da Silva M, Mills K, Wright N, Testad I, Aarsland D, et al (In Press). Loneliness, physical activity and mental health during Covid-19: a longitudinal analysis of depression and anxiety in adults over 50 between 2015 and 2020. International Psychogeriatrics Full text.
Creese BA, Brooker H, Ismail Z, Wesnes K, Adam H, Khan Z, Maria M, Corbett A, Aarsland D, Ballard C, et al (In Press). Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults. American Journal of Geriatric Psychiatry Full text.
Daunt P, Ballard C, Creese B, Davidson G, Hardy J, Oshota O, Pither RJ, Gibson AM (In Press). Polygenic Risk Scoring is an Effective Approach to Predict Those Individuals Most Likely to Decline Cognitively Due to Alzheimer’s Disease. The journal of prevention of Alzheimer's disease Full text.
Pishva SE, Creese B, Smith A, Ballard C, Mill J, Lunnon K (In Press). Psychosis-associated DNA methylomic variation in Alzheimer’s disease cortex. Neurobiology of Aging Full text.
Creese B, Ballard C (In Press). Revisiting criteria for psychosis in Alzheimer’s disease and related dementias- towards better phenotypic classification and biomarker research. Journal of Alzheimer's Disease Full text.
Creese B, Corbett A, Ballard C (In Press). The mental and physical health of older adults with a genetic predisposition for autism. Autism Research: official journal of the International Society for Autism Research Full text.
Griffiths A, Albertyn C, Burnley N, Creese BA, Walwyn R, Holloway I, Safarikova J, Surr C (In Press). Validation of the Cohen-Mansfield Agitation Inventory Observational (CMAI-O) Tool. International Psychogeriatrics Full text.
Malekizadeh Y, Williams G, Kelson M, Whitfield D, Mill J, Collier D, Ballard C, Jeffries A, Creese B (In Press). Whole transcriptome in-silico screening implicates cardiovascular and infectious disease in the mechanism of action underlying atypical antipsychotic side-effects. Alzheimer's and Dementia: Translational Research and Clinical Interventions Full text.

2021

DeMichele-Sweet MAA, Klei L, Creese B, Harwood JC, Weamer EA, McClain L, Sims R, Hernandez I, Moreno-Grau S, Tárraga L, et al (2021). Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease. Molecular Psychiatry

2020

Surr CA, Holloway I, Walwyn RE, Griffiths AW, Meads D, Kelley R, Martin A, McLellan V, Ballard C, Fossey J, et al (2020). Dementia Care Mapping™ to reduce agitation in care home residents with dementia: the EPIC cluster RCT. Health Technol Assess, 24(16), 1-172. Abstract.  Author URL.  Full text.
Creese B, Albertyn CP, Dworkin S, Thomas RS, Wan YM, Ballard C (2020). Executive function but not episodic memory decline associated with visual hallucinations in Parkinson's disease. J Neuropsychol, 14(1), 85-97. Abstract.  Author URL.  Full text.
Ballard C, Kales HC, Lyketsos C, Aarsland D, Creese B, Mills R, Williams H, Sweet RA (2020). Psychosis in Alzheimer's Disease. Curr Neurol Neurosci Rep, 20(12). Abstract.  Author URL.  Full text.
Stewart GR, Corbett A, Ballard C, Creese B, Aarsland D, Hampshire A, Charlton RA, Happé F (2020). Sleep problems and mental health difficulties in older adults who endorse high autistic traits. Research in Autism Spectrum Disorders, 77 Abstract.  Full text.
Stewart GR, Corbett A, Ballard C, Creese B, Aarsland D, Hampshire A, Charlton RA, Happé F (2020). The mental and physical health profiles of older adults who endorse elevated autistic traits. J Gerontol B Psychol Sci Soc Sci Abstract.  Author URL.  Full text.

2019

Creese B, Ballard C, Vasconcelos Da Silva M (2019). Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer’s disease. Translational Psychiatry Full text.
Creese BA, Griffiths A, Brooker H, Corbett A, Aarsland D, Ballard C, Ismail Z (2019). Profile of Mild Behavioral Impairment and Factor Structure of the Mild Behavioral Impairment Checklist in Cognitively Normal Older Adults. International Psychogeriatrics Full text.
Griffiths AW, Surr CA, Creese B, Garrod L, Chenoweth L (2019). The development and use of the assessment of dementia awareness and person-centred care training tool in long-term care. Dementia (London), 18(7-8), 3059-3070. Author URL.  Full text.
Griffiths AW, Albertyn CP, Burnley NL, Creese B, Walwyn R, Holloway I, Safarikova J, Surr CA (2019). Validation of the Cohen-Mansfield Agitation Inventory Observational (CMAI-O) tool - ERRATUM. International Psychogeriatrics, 32(2), 287-287. Abstract.

2018

Nunez KM, Khan Z, Testad I, Lawrence V, Creese B, Corbett A (2018). Current practice and challenges in night-time care for people with dementia living in care homes: a qualitative study. Int J Geriatr Psychiatry, 33(1), e140-e149. Abstract.  Author URL.
Corbett A, Ballard C, Creese BA (2018). Evidence-based management of behavioural and psychological symptoms of dementia. In Michel J-P, Beattie BL, Martin FC, Walston JD (Eds.) Oxford Textbook of Geriatric Medicine, Oxford University Press, 1015-1020.  Abstract.
Creese B, Bell E, Johar I, Francis P, Ballard C, Aarsland D (2018). Glucocerebrosidase mutations and neuropsychiatric phenotypes in Parkinson's disease and Lewy body dementias: Review and meta-analyses. Am J Med Genet B Neuropsychiatr Genet, 177(2), 232-241. Abstract.  Author URL.  Full text.
Creese B, Da Silva MV, Johar I, Ballard C (2018). The modern role of antipsychotics for the treatment of agitation and psychosis in Alzheimer's disease. Expert Rev Neurother, 18(6), 461-467. Abstract.  Author URL.  Full text.

2017

Aarsland D, Creese B, Chaudhuri KR (2017). A new tool to identify patients with Parkinson's disease at increased risk of dementia. Lancet Neurol, 16(8), 576-578. Author URL.
Aarsland D, Creese B, Politis M, Chaudhuri KR, Ffytche DH, Weintraub D, Ballard C (2017). Cognitive decline in Parkinson disease. Nat Rev Neurol, 13(4), 217-231. Abstract.  Author URL.  Full text.
Ffytche DH, Creese B, Politis M, Chaudhuri KR, Weintraub D, Ballard C, Aarsland D (2017). The psychosis spectrum in Parkinson disease. Nat Rev Neurol, 13(2), 81-95. Abstract.  Author URL.  Full text.

2016

Surr CA, Walwyn REA, Lilley-Kelly A, Cicero R, Meads D, Ballard C, Burton K, Chenoweth L, Corbett A, Creese B, et al (2016). Evaluating the effectiveness and cost-effectiveness of Dementia Care Mapping™ to enable person-centred care for people with dementia and their carers (DCM-EPIC) in care homes: study protocol for a randomised controlled trial. Trials, 17(1). Abstract.  Author URL.  Full text.

2015

Ballard C, Thomas A, Gerry S, Yu L-M, Aarsland D, Merritt C, Corbett A, Davison C, Sharma N, Khan Z, et al (2015). A Double-Blind Randomized Placebo-Controlled Withdrawal Trial Comparing Memantine and Antipsychotics for the Long-Term Treatment of Function and Neuropsychiatric Symptoms in People with Alzheimer's Disease (MAIN-AD). JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 16(4), 316-322. Author URL.

2014

Creese B, Ballard C, Aarsland D, Londos E, Sharp S, Jones E (2014). Determining the Association of the 5HTTLPR Polymorphism with Delusions and Hallucinations in Lewy Body Dementias. The American Journal of Geriatric Psychiatry, 22(6), 580-586.
Creese B, Ballard C, Corbett A (2014). Influence of the Tau Haplotype on Progression and Treatment Response of Neuropsychiatric Symptoms in People with Alzheimer's Disease.  Abstract.
Creese B, Corbett A, Jones E, Fox C, Ballard C (2014). Role of the Extended MAPT Haplotype in the Worsening of Psychotic Symptoms and Treatment Response in Alzheimer Disease. Journal of the American Medical Directors Association, 15(12), 934-937.

2013

Creese B, Ballard C, Jones E (2013). Cognitive Impairment in Studies of 5HTTLPR and Psychosis in Alzheimer’s Disease: a Systematic Review. Dementia and Geriatric Cognitive Disorders, 35(3-4), 155-164.

2012

Creese B, Ballard C, Aarsland D, Londos E, Sharp S, Jones E (2012). No association of COMT val158met polymorphism and psychotic symptoms in Lewy body dementias. Neuroscience Letters, 531(1), 1-4.
Corbett A, Smith J, Creese B, Ballard C (2012). Treatment of Behavioral and Psychological Symptoms of Alzheimer’s Disease. Current Treatment Options in Neurology, 14(2), 113-125.

2011

Creese B, Ballard C, Corbett A, Aarsland D (2011). Atypical antipsychotics for the treatment of behavioral and psychological symptoms in dementia, with a particular focus on longer term outcomes and mortality. Expert Opinion on Drug Safety, 10, 35-43.

Refresh publications

External Engagement and Impact

Awards

2019: Alzheimer’s Association ISTAART Neuropsychiatric Syndromes New Investigator Award.


Committee/panel activities

Executive Committee Member: Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) Neuropsychiatric Syndrome Professional Interest Area


Other

Videos

 

Teaching

Cognitive neuroscience and neuropsychology with a particular focus on Alzheimer's disease and neuropsychiatric symptoms

Modules

2021/22


Supervision / Group

Postgraduate researchers

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