University of Exeter Medical School

Bogdan Grigore

Bogdan Grigore

Postdoctoral Research Fellow

 B.Grigore@exeter.ac.uk

 6032

 +44 (0) 1392 726032

 South Cloisters 

 

South Cloisters, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK

Overview

My background is a mix of medicine, psychology, sociology and health policy. I joined ESMI as a PenCLAHRC-funded PhD student exploring expert elicitation in health technology assessment. In 2015 I became part of the Test Group.

Qualifications

  • PhD (2015, Peninsula College of Medicine and Dentistry) in ‘An evaluation of methods for eliciting expert opinion in health technology assessment’
  • BSc (2006, "Spiru Haret" University, Bucharest, Romania ) in Psychology-Sociology
  • MSc (2005) in Cognitive-behavioural Psychotherapies
  • BM (2000, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania)

Career

After graduating from the medical school, I remained at the university as a demonstrator in health psychology, while also conducting a number of qualitative studies on health topics involving both clinicians and patients. For the next eight years, I worked as an EU advisor on pharmaceutical policy for the Romanian Ministry of Health. This included everything from pharmaceutical regulations to pricing and reimbursement policies, and the development and validation of model-based cost-effectiveness analyses of medicines and medical devices. I have now returned to the academia, with an interest on methodological exploration of health technology assessment. My particular interests are the evaluation of diagnostic tests and the use of expert opinion in model-based economic evaluations.

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Research

Research interests

I am interested in the methodological challenges of health technology assessment, in particular, the use of expert elicitation, surrogate endpoints and evaluation of tests.

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Publications

Journal articles

Duer E, Yang H, Robinson S, Grigore B, Sandercock J, Snowsill T, Griffin E, Peters J, Hyde C (2023). Do we know enough about the effect of low-dose computed tomography screening for lung cancer on mortality to act? an updated systematic review, meta-analysis and network meta-analysis of randomised controlled trials 2017 to 2021. Diagn Progn Res, 7(1). Abstract.  Author URL.
Ciani O, Grigore B, Taylor RS (2022). Development of a framework and decision tool for the evaluation of health technologies based on surrogate endpoint evidence. Health Economics Abstract.
Federici C, Reckers-Droog V, Ciani O, Dams F, Grigore B, Kaló Z, Kovács S, Shatrov K, Brouwer W, Drummond M, et al (2021). Coverage with evidence development schemes for medical devices in Europe: characteristics and challenges. European Journal of Health Economics, 22(8), 1253-1273. Abstract.
Ciani O, Grigore B, Blommestein H, de Groot S, Möllenkamp M, Rabbe S, Daubner-Bendes R, Taylor RS (2021). Validity of Surrogate Endpoints and Their Impact on Coverage Recommendations: a Retrospective Analysis across International Health Technology Assessment Agencies. Medical Decision Making, 41(4), 439-452. Abstract.
Medina-Lara A, Grigore B, Lewis R, Peters J, Price S, Landa P, Robinson S, Neal R, Hamilton W, Spencer AE, et al (2020). Cancer diagnostic tools to aid decision-making in primary care: mixed-methods systematic reviews and cost-effectiveness analysis. Health Technology Assessment, 24(66), 1-332. Abstract.
Grigore B, Lewis R, Peters J, Robinson S, Hyde CJ (2020). Development, validation and effectiveness of diagnostic prediction tools for colorectal cancer in primary care: a systematic review. BMC Cancer, 20(1). Abstract.
Grigore B, Ciani O, Dams F, Federici C, de Groot S, Möllenkamp M, Rabbe S, Shatrov K, Zemplenyi A, Taylor RS, et al (2020). Surrogate Endpoints in Health Technology Assessment: an International Review of Methodological Guidelines. PharmacoEconomics, 38(10), 1055-1070.
Grigore B, Peters J, Hyde C, Stein K (2017). EXPLICIT: a feasibility study of remote expert elicitation in health technology assessment. BMC Med Inform Decis Mak, 17(1). Abstract.  Author URL.
Gopalakrishna G, Langendam M, Scholten R, Bossuyt P, Leeflang M, Noel-Storr A, Thomas J, Marshall I, Wallace B, Whiting P, et al (2017). Erratum to: Methods for evaluating medical tests and biomarkers. Diagn Progn Res, 1 Abstract.  Author URL.
Bojke L, Grigore B, Jankovic D, Peters J, Soares M, Stein K (2017). Informing Reimbursement Decisions Using Cost-Effectiveness Modelling: a Guide to the Process of Generating Elicited Priors to Capture Model Uncertainties. Pharmacoeconomics, 35(9), 867-877. Abstract.  Author URL.
Grigore B, Peters J, Hyde C, Stein K (2016). A comparison of two methods for expert elicitation in health technology assessments. BMC Med Res Methodol, 16 Abstract.  Author URL.
Zhelev Z, Hyde C, Fitzgerald JE, Ukoumunne O, Briscoe S, Chisnell J, Grigore B (2015). Tests for screening for hearing loss in children about to start school. Cochrane Database of Systematic Reviews, 2015(11). Abstract.
Grigore B, Peters J, Hyde C, Stein K (2013). Methods to elicit probability distributions from experts: a systematic review of reported practice in health technology assessment. Pharmacoeconomics, 31(11), 991-1003. Abstract.  Author URL.
Mosoiu D, Mungiu OC, Gigore B, Landon A (2007). Romania: changing the regulatory environment. J Pain Symptom Manage, 33(5), 610-614. Abstract.  Author URL.

Conferences

Ciani O, Grigore B, Taylor R (2019). WHAT METHODS ARE APPLIED IN ASSESSESSING THE CLINICAL AND COST EFFECTIVENESS OF HEALTH TECHNOLOGIES BASED ON THE USE OF SURROGATE OUTCOMES: a COMPARISON OF EVALUATION REPORTS ACROSS INTERNATIONAL HEALTH TECHNOLOGY ASSESSMENT AGENCIES.  Author URL.
Hunt HA, Hyde CJ (2017). An overview of systematic reviews summarising the accuracy of brief cognitive assessments for identifying dementia in primary care. Methods for Evaluating Medical Tests and Biomarkers. 19th - 20th Jul 2016. Abstract.
Grigore B, Peters J, Hyde C, Stein K (2013). REPRESENTING UNCERTAINTY OF EXPERT OPINION IN HEALTH TECHNOLOGY ASSESSMENT THROUGH THE USE OF SUBJECTIVE PROBABILITIES.  Author URL.

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