About us

Evidence Synthesis & Modelling for Health Improvement (ESMI) is a vibrant and multidisciplinary research group which specialises in the synthesis of research evidence for informing health policy and practice.  We have been conducting systematic reviews and model-based economic analyses of health technologies and complex health programmes since 2001 (up to 2014, as the Peninsula Technology Assessment Group, PenTAG).  Our work spans both ongoing contracts to support national policy-making agencies, NIHR-funded evidence syntheses, and internationally recognised methodological research relevant to evidence synthesis and improving the influence of research on policy-making.

We have a number of major work streams, which fund most of our 35+ research staff:

Our methodological research includes

  • Applying and evaluating new methods of evidence synthesis
  • Developing and evaluating methods for elicitation of expert opinion in HTA
  • Assessing the use and validation of surrogate outcomes in HTA
  • Advancing methods for cost-effectiveness analysis
  • Evaluating novel search strategies and alternative bibliographic resources

ESMI is one of a number of established research groups within the Institute of Health Research. ESMI researchers also lead initiatives to build capacity and collaboration amongst those in the University of Exeter Medical School, and the wider University, who either use or wish to learn about systematic review and evidence synthesis methods:

  • PenSR – Systematic Review Discussion Group
  • The Realist Hive – a reading group, blog and online resource for those interested in learning about realist approaches
  • Search and Review Clinics – providing project-specific advice to researchers and postgraduate students


Welcome, and enjoy meeting our team.

Staff spotlight

ESMI's paper pick

See which of our papers is currently in the spotlight