Prof Anna Murray
Scientist with expertise in common disease genomics
Associate Professor in Human Genetics
Anna is an Associate Professor in Human Genetics in the College of Medicine and Health. She is part of the 'Genetics of Complex Traits' research group and Programme Director of the Masters in Genomic Medicine. Her main research expertise is in the field of reproductive genetics and she has published on single gene mutations which cause premature ovarian failure and also genome-wide studies to detect novel loci involved in reproductive ageing.
Anna is also discipline lead for genetics at UEMS. She was involved in the development and implementation of the Bachelor of Medical Sciences degree programme. Anna runs Research in Action Student Selected Components in her research field, is an academic and personal tutor, delivers lectures on genetics and facilitates problem based learning and LSRC sessions across the Medical School taught programmes.
Dr Jonathan Locke
Scientist with expertise in molecular biology
Lecturer in Postgraduate Education
Jon received a Masters of Biology in Molecular & Cellular Biology from the University of Bath in 2006. Following this, he obtained a PhD from the Peninsula Medical School (Universities of Exeter & Plymouth) under the supervision of Dr Lorna Harries. During his doctoral studies, he became interested in understanding how genetics can be used to further our understanding of disease biology and pathogenesis. Following completion of his PhD he has continued to work in the area of diabetes genetics.
Dr Locke also teaches on the MSc Genomic Medicine and BSc Medical Sciences programmes. He is, in particular, interested in developing student’s transferable skills, developing such material for Academic Tutor Groups and taught modules (e.g. Professional & Research Skills).
Prof Caroline Wright
Scientist with expertise in rare disease genomics
Professor in Genomic Medicine
Caroline trained in Natural Sciences at the University of Cambridge, where she obtained an MA, MSci and PhD specialising in biological chemistry. She joined the University of Exeter as a Senior Lecturer in 2017 and was promoted to a personal chair in genomic medicine in 2020. Her main research interests are in the use of genome-wide sequencing technologies for the diagnosis of rare diseases, particularly developmental disorders. She is interested in understanding the penetrance of rare disease-causing variants, improving variant filtering and interpretation, modelling the effect of missense variants using in silico protein structural analysis, and exploring the policy and ethical issues associated with implementation of genome-wide sequencing in healthcare.
Caroline leads the Enhanced Interpretation Genomics England Clinical Interpretation Partnership (GeCIP), and was previously seconded part-time to Genomics England as scientific lead for validation and feedback in the early stages of the UK 100,000 genomes project. She previously worked at the Wellcome Sanger Institute in Cambridge, where she remains a visiting scientist and part of the management committee for the UK Deciphering Developmental Disorders Study. Prior to that, she was Head of Science at the PHG Foundation in Cambridge.
Dr Emma Baple
Consultant clinical geneticist with expertise in community genetics
Clinical Senior Lecturer
Emma is a Clinical Senior Lecturer in Genomic Medicine. Emma leads the Rare Disease Research group at the University of Exeter College of Medicine and Health, alongside Professor Andrew Crosby with whom she works closely. Her principal area of interest is in the use of new genetic technologies to identify the cause of rare genetic disorders and the translation of that knowledge into improved clinical diagnostic testing and treatment strategies. Emma’s main area of research involves the investigation of the molecular causes of inherited disorders within a community setting, stemming from the identification of the causal disease gene through to more detailed studies of the biological pathway and disease mechanism responsible.
Emma is also the Clinical Lead for Rare Disease Validation and Feedback at Genomics England, as well as the Medical Lead for Rare Disease in the Southwest Genomic Laboratory Hub.
Dr Leigh Jackson
Scientist with expertise in genomic medicine
Lecturer in Genomic Medicine (University of Exeter Medical School)
Leigh Jackson graduated from the University of Nottingham with a degree in Genetics and a PhD in Stem Cell Genetics and their utility in the treatment if neurodevelopmental disorders. He went on to work in an endometrial cancer and fertility laboratory where he became interested in the ethical issues surrounding genetic testing. Leigh has conducted research around incidental findings and direct-to-consumer testing and the impacts these have on patients and the public.
After serving as the Education and Training lead for the South West Genomic Medicine Centre, Leigh moved to the University of Exeter to take up a position as Lecturer in Genomic Medicine. He has extensive teaching experience including the development of the Gen-Equip modules for primary care genetics, which was awarded a Gastein Forum, European health award, as well as teaching on the MSc in Genomic Medicine where he leads the ethical, social and legal issues module and co-leading an undergraduate module on Medical Genomics. Leigh is also Scientific lead for the COG-Train Programme providing training to lower and middle income countries to increase SARS-CoV-2 sequencing capacity. During the pandemic, Leigh was seconded to COG-UK to act as Scientific Project Manager, overseeing all National sequencing projects.