Neuroscience and CNS Disease

Our research focuses on understanding basic functions of the central nervous system and the mechanisms driving neurodevelopment and neurodegeneration.

We research mental health conditions and dementia, and we’re pioneering studies into the neuroendocrine system's role in regulating behaviour and physiology. We employ cutting-edge methods in genomics and electrophysiology, exploring the epigenome and transcript diversity in preclinical disease models and human tissue from patients.

Our state-of-the-art neuroimaging centre supports clinical trials for novel treatments of neurodegenerative diseases, while at a population level, our genetics research uses whole genome sequencing to identify the causes of rare neurodevelopmental disorders, and also investigates links between metabolic phenotypes and mental health conditions. By taking an interdisciplinary approach, we aim to identify the underlying mechanisms of brain diseases to improve patient treatment.