Journal articles
Ellingford RA, Tojo M, Basson MA, Andreae LC (2024). Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex.
ACS CHEMICAL NEUROSCIENCE,
15(8), 1635-1642.
Author URL.
Basson MA (2024). Neurodevelopmental functions of CHD8: new insights and questions.
BIOCHEMICAL SOCIETY TRANSACTIONS,
52(1), 15-27.
Author URL.
Pérez-Sisqués L, Bhatt SU, Matuleviciute R, Gileadi TE, Kramar E, Graham A, Garcia FG, Keiser A, Matheos DP, Cain JA, et al (2024). The Intellectual Disability Risk Gene<i>Kdm5b</i>Regulates Long-Term Memory Consolidation in the Hippocampus.
The Journal of Neuroscience,
44(19), e1544232024-e1544232024.
Abstract.
Hu X, Xiao W, Lei Y, Green A, Lee X, Maradana MR, Gao Y, Xie X, Wang R, Chennell G, et al (2023). Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier.
Nature Communications,
14(1).
Abstract.
Donovan APA, Rosko L, Ellegood J, Redhead Y, Green JBA, Lerch JP, Huang JKK, Basson MA (2023). Pervasive cortical and white matter anomalies in a mouse model for CHARGE syndrome.
JOURNAL OF ANATOMY,
243(1), 51-65.
Author URL.
Kerschbamer E, Arnoldi M, Tripathi T, Pellegrini M, Maturi S, Erdin S, Salviato E, Di Leva F, Sebestyen E, Dassi E, et al (2022). CHD8 suppression impacts on histone H3 lysine 36 trimethylation and alters RNA alternative splicing.
NUCLEIC ACIDS RESEARCH,
50(22), 12809-12828.
Author URL.
Oates S, Absoud M, Goyal S, Bayley S, Baulcomb J, Sims A, Riddett A, Allis K, Brasch-Andersen C, Balasubramanian M, et al (2021). <i>ZMYND11</i> variants are a novel cause of centrotemporal and generalised epilepsies with neurodevelopmental disorder.
CLINICAL GENETICS,
100(4), 412-429.
Author URL.
Whittaker DE, Oleari R, Gregory LC, Le Quesne-Stabej P, Williams HJ, Torpiano JG, Formosa N, Cachia MJ, Field D, Lettieri A, et al (2021). A recessive <i>PRDM13</i> mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia.
JOURNAL OF CLINICAL INVESTIGATION,
131(24).
Author URL.
Zerbi V, Pagani M, Markicevic M, Matteoli M, Pozzi D, Fagiolini M, Bozzi Y, Galbusera A, Scattoni M, Provenzano G, et al (2021). Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes.
MOLECULAR PSYCHIATRY,
26(12), 7610-7620.
Author URL.
Ellingford RA, Panasiuk MJ, de Meritens ER, Shaunak R, Naybour L, Browne L, Basson MA, Andreae LC (2021). Cell-type-specific synaptic imbalance and disrupted homeostatic plasticity in cortical circuits of ASD-associated <i>Chd8</i> haploinsufficient mice.
MOLECULAR PSYCHIATRY,
26(7), 3614-3624.
Author URL.
Hurley S, Mohan C, Suetterlin P, Ellingford R, Riegman KLH, Ellegood J, Caruso A, Michetti C, Brock O, Evans R, et al (2021). Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development.
MOLECULAR AUTISM,
12(1).
Author URL.
Gileadi TE, Swamy AK, Hore Z, Horswell S, Ellegood J, Mohan C, Mizuno K, Lundebye A-K, Giese KP, Stockinger B, et al (2021). Effects of Low-Dose Gestational TCDD Exposure on Behavior and on Hippocampal Neuron Morphology and Gene Expression in Mice.
ENVIRONMENTAL HEALTH PERSPECTIVES,
129(5).
Author URL.
Badodi S, Pomella N, Zhang X, Rosser G, Whittingham J, Niklison-Chirou MV, Lim YM, Brandner S, Morrison G, Pollard SM, et al (2021). Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation.
NATURE COMMUNICATIONS,
12(1).
Author URL.
Ahmed M, Moon R, Prajapati RS, James E, Basson MA, Streit A (2021). The chromatin remodelling factor Chd7 protects auditory neurons and sensory hair cells from stress-induced degeneration.
COMMUNICATIONS BIOLOGY,
4(1).
Author URL.
Kelly E, Meng F, Fujita H, Morgado F, Kazemi Y, Rice LC, Ren C, Escamilla CO, Gibson JM, Sajadi S, et al (2020). Regulation of autism-relevant behaviors by cerebellar-prefrontal cortical circuits.
Nat Neurosci,
23(9), 1102-1110.
Abstract.
Author URL.
Saric N, Selby M, Ramaswamy V, Kool M, Stockinger B, Hogstrand C, Williamson D, Marino S, Taylor MD, Clifford SC, et al (2020). The AHR pathway represses TGFβ-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma.
SCIENTIFIC REPORTS,
10(1).
Author URL.
Gutierrez-Barragan D, Basson MA, Panzeri S, Gozzi A (2019). Infraslow State Fluctuations Govern Spontaneous fMRI Network Dynamics.
CURRENT BIOLOGY,
29(14), 2295-+.
Author URL.
Vaquero M, Cuesta S, Anerillas C, Altes G, Ribera J, Basson MA, Licht JD, Egea J, Encinas M (2019). Sprouty1 Controls Genitourinary Development via its N-Terminal Tyrosine.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY,
30(8), 1398-1411.
Author URL.
Suetterlin P, Hurley S, Mohan C, Riegman KLH, Pagani M, Caruso A, Ellegood J, Galbusera A, Crespo-Enriquez I, Michetti C, et al (2018). Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in <i>Chd8</i> Haploinsufficient Mice.
CEREBRAL CORTEX,
28(6), 2192-2206.
Author URL.
Kasah S, Oddy C, Basson MA (2018). Autism-linked CHD gene expression patterns during development predict multi-organ disease phenotypes.
JOURNAL OF ANATOMY,
233(6), 755-769.
Author URL.
Janecka M, Mill J, Basson MA, Goriely A, Spiers H, Reichenberg A, Schalkwyk L, Fernandes C (2017). Advanced paternal age effects in neurodevelopmental disorders-review of potential underlying mechanisms.
Transl Psychiatry,
7(1).
Abstract.
Author URL.
Donovan APA, Yu T, Ellegood J, Riegman KLH, de Geus C, van Ravenswaaij-Arts C, Fernandes C, Lerch JP, Basson MA (2017). Cerebellar Vermis and Midbrain Hypoplasia Upon Conditional Deletion of <i>Chd7</i> from the Embryonic Mid-Hindbrain Region.
FRONTIERS IN NEUROANATOMY,
11 Author URL.
Badodi S, Dubuc A, Zhang X, Rosser G, Jaeger MDC, Kameda-Smith MM, Morrissy AS, Guilhamon P, Suetterlin P, Li X-N, et al (2017). Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma.
CELL REPORTS,
21(10), 2772-2784.
Author URL.
Whittaker DE, Kasah S, Donovan APA, Ellegood J, Riegman KLH, Volk HA, McGonnell I, Lerch JP, Basson MA (2017). Distinct cerebellar foliation anomalies in a <i>CHD7</i> haploinsufficient mouse model of CHARGE syndrome.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS,
175(4), 465-477.
Author URL.
Ahmed MU, Maurya AK, Cheng L, Jorge EC, Schubert FR, Maire P, Basson MA, Ingham PW, Dietrich S (2017). Engrailed controls epaxial-hypaxial muscle innervation and the establishment of vertebrate three-dimensional mobility.
Developmental Biology,
430(1), 90-104.
Abstract.
Whittaker DE, Riegman KLH, Kasah S, Mohan C, Yu T, Sala BP, Hebaishi H, Caruso A, Marques AC, Michetti C, et al (2017). The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression.
JOURNAL OF CLINICAL INVESTIGATION,
127(3), 874-887.
Author URL.
Donovan APA, Basson MA (2017). The neuroanatomy of autism - a developmental perspective.
JOURNAL OF ANATOMY,
230(1), 4-15.
Author URL.
Balasooriya GI, Johnson J-A, Basson MA, Rawlins EL (2016). An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium.
DEVELOPMENTAL CELL,
37(1), 85-97.
Author URL.
Jones KM, Saric N, Russell JP, Andoniadou CL, Scambler PJ, Basson MA (2015). CHD7 Maintains Neural Stem Cell Quiescence and Prevents Premature Stem Cell Depletion in the Adult Hippocampus.
STEM CELLS,
33(1), 196-210.
Author URL.
Basson MA, van Ravenswaaij-Arts C (2015). Functional Insights into Chromatin Remodelling from Studies on CHARGE Syndrome.
TRENDS IN GENETICS,
31(10), 600-611.
Author URL.
Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T (2014). <i>Gli3</i> Controls Corpus Callosum Formation by Positioning Midline Guideposts During Telencephalic Patterning.
CEREBRAL CORTEX,
24(1), 186-198.
Author URL.
Dyer C, Blanc E, Hanisch A, Roehl H, Otto GW, Yu T, Basson MA, Knight R (2014). A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain.
DEVELOPMENT,
141(1), 63-72.
Author URL.
Ching ST, Cunha GR, Baskin LS, Basson MA, Klein OD (2014). Coordinated activity of <i>Spry1</i> and <i>Spry2</i> is required for normal development of the external genitalia.
DEVELOPMENTAL BIOLOGY,
386(1), 1-11.
Author URL.
Jackson A, Kasah S, Mansour SL, Morrow B, Basson MA (2014). Endoderm-specific deletion of Tbx1 reveals an FGF-independent role for Tbx1 in pharyngeal apparatus morphogenesis.
Dev Dyn,
243(9), 1143-1151.
Abstract.
Author URL.
Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T (2014). Heparan Sulfotransferases Hs6st1 and Hs2st Keep Erk in Check for Mouse Corpus Callosum Development.
JOURNAL OF NEUROSCIENCE,
34(6), 2389-2401.
Author URL.
Basson MA, Wingate RJ (2013). Congenital hypoplasia of the cerebellum: developmental causes and behavioral consequences.
FRONTIERS IN NEUROANATOMY,
7 Author URL.
Yu T, Meiners LC, Danielsen K, Wong MTY, Bowler T, Reinberg D, Scambler PJ, van Ravenswaaij-Arts CMA, Basson MA (2013). Deregulated FGF and homeotic gene expression underlies cerebellar vermis hypoplasia in CHARGE syndrome.
ELIFE,
2 Author URL.
Pitera JE, Woolf AS, Basson MA, Scambler PJ (2012). <i>Sprouty1</i> Haploinsufficiency Prevents Renal Agenesis in a Model of Fraser Syndrome.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY,
23(11), 1790-1796.
Author URL.
Simrick S, Szumska D, Gardiner JR, Jones K, Sagar K, Morrow B, Bhattacharya S, Basson MA (2012). Biallelic expression of Tbx1 protects the embryo from developmental defects caused by increased receptor tyrosine kinase signaling.
DEVELOPMENTAL DYNAMICS,
241(8), 1310-1324.
Author URL.
Gardiner JR, Jackson AL, Gordon J, Lickert H, Manley NR, Basson MA (2012). Localised inhibition of FGF signalling in the third pharyngeal pouch is required for normal thymus and parathyroid organogenesis.
DEVELOPMENT,
139(18), 3456-3466.
Author URL.
Economou AD, Ohazama A, Porntaveetus T, Sharpe PT, Kondo S, Basson MA, Gritli-Linde A, Cobourne MT, Green JBA (2012). Periodic stripe formation by a Turing mechanism operating at growth zones in the mammalian palate.
NATURE GENETICS,
44(3), 348-U163.
Author URL.
Collins S, Waickman A, Basson A, Kupfer A, Licht JD, Horton MR, Powell JD (2012). Regulation of CD4⁺ and CD8⁺ effector responses by Sprouty-1.
PLoS One,
7(11).
Abstract.
Author URL.
Basson MA (2012). Signaling in Cell Differentiation and Morphogenesis.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY,
4(6).
Author URL.
Macia A, Gallel P, Vaquero M, Gou-Fabregas M, Santacana M, Maliszewska A, Robledo M, Gardiner JR, Basson MA, Matias-Guiu X, et al (2012). Sprouty1 is a candidate tumor-suppressor gene in medullary thyroid carcinoma.
ONCOGENE,
31(35), 3961-3972.
Author URL.
Chakkalakal JV, Jones KM, Basson MA, Brack AS (2012). The aged niche disrupts muscle stem cell quiescence.
NATURE,
490(7420), 355-+.
Author URL.
Mao Y, Mulvaney J, Zakaria S, Yu T, Morgan KM, Allen S, Basson MA, Francis-West P, Irvine KD (2011). Characterization of a <i>Dchs1</i> mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development.
DEVELOPMENT,
138(5), 947-957.
Author URL.
Porntaveetus T, Otsuka-Tanaka Y, Basson MA, Moon AM, Sharpe PT, Ohazama A (2011). Expression of fibroblast growth factors (Fgfs) in murine tooth development.
JOURNAL OF ANATOMY,
218(5), 534-543.
Author URL.
Simrick S, Lickert H, Basson MA (2011). Sprouty genes are essential for the normal development of epibranchial ganglia in the mouse embryo.
DEVELOPMENTAL BIOLOGY,
358(1), 147-155.
Author URL.
Yu T, Yaguchi Y, Echevarria D, Martinez S, Basson MA (2011). Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum.
DEVELOPMENT,
138(14), 2957-2968.
Author URL.
Akbulut S, Reddi AL, Aggarwal P, Ambardekar C, Canciani B, Kim MKH, Hix L, Vilimas T, Mason J, Basson MA, et al (2010). Sprouty Proteins Inhibit Receptor-mediated Activation of Phosphatidylinositol-specific Phospholipase C.
MOLECULAR BIOLOGY OF THE CELL,
21(19), 3487-3496.
Author URL.
Shea KL, Xiang W, LaPorta VS, Licht JD, Keller C, Basson MA, Brack AS (2010). Sprouty1 Regulates Reversible Quiescence of a Self-Renewing Adult Muscle Stem Cell Pool during Regeneration.
CELL STEM CELL,
6(2), 117-129.
Author URL.
Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA (2009). Fibroblast Growth Factor (FGF) Gene Expression in the Developing Cerebellum Suggests Multiple Roles for FGF Signaling During Cerebellar Morphogenesis and Development.
DEVELOPMENTAL DYNAMICS,
238(8), 2058-2072.
Author URL.
Randall V, McCue K, Roberts C, Kyriakopoulou V, Beddow S, Barrett AN, Vitelli F, Prescott K, Shaw-Smith C, Devriendt K, et al (2009). Great vessel development requires biallelic expression of <i>Chd7</i> and <i>Tbx1</i> in pharyngeal ectoderm in mice.
JOURNAL OF CLINICAL INVESTIGATION,
119(11), 3301-3310.
Author URL.
Rozen EJ, Schmidt H, Dolcet X, Basson MA, Jain S, Encinas M (2009). Loss of Sprouty1 Rescues Renal Agenesis Caused by Ret Mutation.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY,
20(2), 255-259.
Author URL.
Calmont A, Ivins S, Van Bueren KL, Papangeli I, Kyriakopoulou V, Andrews WD, Martin JF, Moon AM, Illingworth EA, Basson MA, et al (2009). Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating <i>Gbx2</i> expression in the pharyngeal ectoderm.
DEVELOPMENT,
136(18), 3173-3183.
Author URL.
Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR (2008). An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors.
DEVELOPMENT,
135(2), 377-385.
Author URL.
Parravicini V, Field A-C, Tomlinson PD, Basson MA, Zamoyska R (2008). Itch<SUP>-/-</SUP>αβ and γδ T cells independently contribute to autoimmunity in Itchy mice.
BLOOD,
111(8), 4273-4282.
Author URL.
Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, et al (2008). MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts.
NATURE,
456(7224), 980-U83.
Author URL.
Basson MA, Echevarria D, Ahn CP, Sudarov A, Joyner AL, Mason IJ, Martinez S, Martin GR (2008). Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development.
DEVELOPMENT,
135(5), 889-898.
Author URL.
Basson MA, Watson-Johnson J, Shakya R, Akbulut S, Hyink D, Costantini FD, Wilson PD, Mason IJ, Licht JD (2006). Branching morphogenesis of the ureteric epithelium during kidney development is coordinated by the opposing functions of GDNF and Sprouty1.
DEVELOPMENTAL BIOLOGY,
299(2), 466-477.
Author URL.
Mason JM, Morrison DJ, Basson MA, Licht JD (2006). Sprouty proteins: Multifaceted negative-feedback regulators of receptor tyrosine kinase signaling.
Trends in Cell Biology,
16(1), 45-54.
Abstract.
Basson MA, Akbulut S, Watson-Johnson J, Simon R, Carroll TJ, Shakya R, Gross I, Martin GR, Lufkin T, McMahon AP, et al (2005). Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction.
Developmental Cell,
8(2), 229-239.
Abstract.
Lin W, Jing N, Basson MA, Dierich A, Licht J, Ang SL (2005). Synergistic activity of Sef and Sprouty proteins in regulating the expression of Gbx2 in the mid-hindbrain region.
Genesis (United States),
41(3), 110-115.
Abstract.
Zamoyska R, Basson A, Filby A, Legname G, Lovatt M, Seddon B (2003). The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation.
Immunol Rev,
191, 107-118.
Abstract.
Author URL.
Basson MA, Zamoyska R (2001). Insights into T-cell development from studies using transgenic and knockout mice.
Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology,
18(1), 11-23.
Abstract.
Basson MA, Zamoyska R (2000). The CD4/CD8 lineage decision: Integration of signalling pathways.
Immunology Today,
21(10), 509-514.
Abstract.
Basson MA, Bommhardt U, Cole MS, Tso JY, Zamoyska R (1998). Cd3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity.
Journal of Experimental Medicine,
187(8), 1249-1260.
Abstract.