Dr Talitha Kerrigan
Senior Lecturer in Neuroscience
T.L.Kerrigan@exeter.ac.uk
01392 72 7080
College House G05
College House, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK
Overview
Qualifications
- 2004 BSc (Hons) Anatomical Science, University of Bristol
- 2008 PhD Neurophysiology, University of Leeds
- 2015 PCAP, University of Exeter
- 2016 Fellow of the Higher Education Academy
Research group links
Research
Research interests
Broad research specialisms
- Educational Neuroscience
- Models of Dementia
- Neuroinflammation and glial biology
- Induced pluripotent stem cells (iPSCs)
- In vitro electrophysiology
- Synaptic and intrinsic neuroplasticity
Professional Memberships
Physiological Society
British Neuroscience Association
British Society for Neuroendocrinology
Society for Neuroscience
Research projects
Current Projects:
- Neuron-Microglia Interactions During Neuronal Network Oscillations: Implications for Dementia. (GW4 BioMed MRC Doctoral Studentship with Dr Jon Brown, Exeter)
- Functional characterisation of iPSC- derived neural cells from individuals with high genetic loading for AD. (Alzheimer’s Society PhD studentship in collaboration with Prof. Katie Lunnon, Exeter).
- The dynamic role of astrocyte secreted APOE4 in Alzheimer’s disease; investigating using human induced pluripotent stem cells (Alzheimer’s Society Grant, in collaboration with Prof Andy Randall, Exeter and Prof Seth Love, Bristol)
Grants/Funding:
2019 Alzheimer’s Research UK Oxford Network Pilot Grant
Role: Co-Investigator (PI – Dr L.Thei University of Reading)
Title: TRPM8 Ion Channel Distribution in Aged J20 Microglia
2018 Alzheimer’s Research UK South West Network Centre Equipment Grant
Role: Co-Investigator (PI – Jennifer Imm, Exeter)
Title: Lonza Cytosmart 2
2017 Alzheimer’s Research UK Network Cooperation Grant
Role: PI (PI – Dr Mark Dallas, Reading)
Title: Microglial remodelling in dementia
2017 Alzheimer's Society Undergraduate Summer Studentship
Role: Co-Investigator (PI – Dr Craig Beall, Exeter)
Title: Measurement of cellular metabolism in IPSC-derived astrocytes with high genetic load for Alzheimer's disease - impact of glucose variation
2016 BRACE Pilot Grant
Role: PI
Title: Amyloid-beta clearance and neuronal function in a human model of Alzheimer’s disease.
2016 Alzheimer’s Research UK South West Network Centre Pilot Grant
Role: Co-Investigator (PI – Jennifer Imm)
Title: Characterisation of iPSC-derived microglial cells with high and low genetic loading for Alzheimer’s disease.
2016 Alzheimer’s Research UK Equipment Grant
Role: Co-Investigator (PI - Prof Andrew Randall)
Title: Contribution to the purchase of a Ti-Sapphire laser to enable establishment of multiphoton fluorescence imaging facility.
2015 Alzheimer’s Research UK Network Centre Pilot Grant
Role: PI
Title: Epigenetic regulation of amyloid beta clearance and neuronal function in a human model of Alzheimer’s disease.
Research networks
Research grants
- 2019 GW4 BioMed
Neuron-Microglia Interactions During Neuronal Network Oscillations: Implications for Dementia
Publications
Journal articles
Conferences
External Engagement and Impact
Awards
- 2019 – Above and Beyond Award for Impact
- 2019 – Above and Beyond Award for Impact
- 2018 – Above and Beyond Award for Collaboration
- 2016 – Aspire Fellow
Committee/panel activities
- British Neuroscience Association Local Group Representative
- Physiological Society Neuroscience Theme Lead
- Alzheimer’s Research UK Early-career representative
Editorial responsibilities
- Associate Editor - Journal of Embryology and Stem Cell Research
Invited lectures
June 2018: Alzheimer’s Research UK Southwest Network Open public day
Sept 2017: Exeter Dementia Day, Rougemont Hotel, Exeter
August 2017: 7th International Conference on Dementia, Toronto
July 2016: Alzheimer’s Research UK Southwest Network meeting
June 2016: BRACE and Exeter Dementia Action Alliance Workshop
May 2016: Pint of Science Festival Exeter
September 2015: GW4 Early career Neuroscience Day, Bristol
Teaching
BSc Neuroscience:- Introduction to Neuroscience (NEU1006)
- Advanced Methods in Neuroscience (NEU2001)
- Neuroanatomy (NEU2004)
- Neural Circuits (NEU2018)
- Neuropharmacology (NEU2019)
- Frontiers in Neuroscience (NEU3008)
- Neuroimmunology (NEU3030)
BMBS:
- SSU provider and facilitator
BSc Medical Imaging:
Anatomy and Physiology (PAM1011)
Modules
2024/25
- NEU3030 - Neuroimmunology
- NEUM001 - Molecular and Cellular Neuroscience
- NEUM006 - Neuroscience Research Dissertation
Supervision / Group
Postgraduate researchers
- Meg Elley GW4 BioMed MRC Doctoral Studentship
Alumni
- Jennifer Imm PhD student
- Laura Thei Postdoctoral Researcher ARUK funded
- Sam Washer Final year project student