Dr Rosie Bamford

About me:

Rosie is a postdoctoral researcher in the Complex Disease Epigenomics group at the University of Exeter Medical School. Her research is focused on identifying transcriptional variation associated with neuropsychiatric and neurodegenerative disorders. She specialises in long read and single cell RNA sequencing technologies, which she currently applies to study neurodevelopment in human brain samples and organoids. She is implementing the use of sequencing technologies to investigate neurodevelopmental trajectories of gene regulation. 

Background:

Rosie graduated with an MPhys in Physics from the University of St Andrews. Subsequently, she joined the Physical Sciences of Imaging in the Biomedical Sciences (PSIBS) Doctoral Training Centre at the University of Birmingham, where she studied for an integrated MSc and PhD. Her PhD project focused on designing DNA probes for in vitro SNP sensing, under the supervision of Prof. Jim Tucker. Rosie initially worked in the School of Biosciences and Living Systems Institute at the University of Exeter. Working with Dr. Stefano Pagliara, she investigated gene expression in antibiotic tolerant bacteria, using a combination of microfluidics and microscopy. Her first role in the Complex Disease Epigenetics group was supporting the work of Dr. Asami Oguro-Ando. Rosie mainly focussed on genes associated with Autism Spectrum Disorder and Alzheimer’s disease, and their underlying molecular pathways, using a combination of molecular biology and gene-editing approaches. Rosie currently works for Professor Jon Mill developing long read sequencing technologies and single cell genomics. She is interested in novel sequencing applications and works closely with Dr. Aaron Jeffries and the Exeter Sequencing Service.

Interests:

Neurodevelopment and aging

Neuropsyciatric disease

Long read sequencing technologies

Targeted sequencing

Single cell and spatial sequencing

Long read sequencing bioinformatics

Qualifications:

PhD Physical Sciences of Imaging in the Biomedical Sciences (University of Birmingham)

MSc Physical Sciences of Imaging in the Biomedical Sciences (University of Birmingham)

MPhys Physics (University of St Andrews)