A pragmatic randomised controlled trial to evaluate physical activity as a treatment for depression (TREAD)

A pragmatic randomised controlled trial to evaluate physical activity as a treatment for depression (TREAD)

The TREAD Study is a pragmatic, multi-centre, two-arm randomised controlled trial which investigated whether facilitated physical activity could change outcomes for depressed patients consulting in the primary care setting. The Peninsula Medical School and the School of Sports and Health Sciences are working in collaboration with the University of Bristol (Principal Investigator - Professor Glyn Lewis) and the study is funded by the HTA. Between August 2007 and October 2009, a total of 361 patients with a recent diagnosis of depression were recruited through GP practices in the Bristol and Exeter areas and were randomly allocated to receive their usual GP care or the support and advice of a physical activity facilitator in addition to their usual GP care. All patients were followed up for a year after entering the trial.Data collection was completed in November 2010 and statistical analyses are now being undertaken.

It is hoped that TREAD will provide a better understanding of how facilitated physical activity could be used within the primary care setting and make a timely contribution to the evidence base on treating depression from which patients, clinicians and policy-makers can benefit.

A paper describing the protocol has been published at http://www.trialsjournal.com/content/11/1/105

Core Staff:

Professor John Campbell - Professor of General Practice & Primary Care
Ms Rachel Winder - Research Fellow

Additional Staff:

Professor Glyn Lewis - Principal Investigator (University of Bristol)
Ms Melanie Chalder - Trial Co-ordinator (University of Bristol)
Professor Adrian Taylor – Intervention Advisor
 

Location:

University of Exeter Medical School (Primary Care)
Smeall Building
St Luke’s Campus
Exeter
EX1 2LU
Tel: 01392 722741
Fax: 01392 432223