Journal articles
Locke JM, da Silva Xavier G, Rutter, GA, Harries LW (In Press). An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes.
Diabetologia Abstract.
Bramwell LR, Frankum R, Harries LW (2024). Repurposing Drugs for Senotherapeutic Effect: Potential Senomorphic Effects of Female Synthetic Hormones. Cells, 13(6).
Manni E, Jeffery N, Chambers D, Slade L, Etheridge T, Harries LW (2023). An evaluation of the role of miR-361-5p in senescence and systemic ageing. Experimental Gerontology, 174, 112127-112127.
Mou Z, Spencer J, McGrath JS, Harries LW (2023). Comprehensive analysis of alternative splicing across multiple transcriptomic cohorts reveals prognostic signatures in prostate cancer.
Human Genomics,
17(1).
Abstract.
Harries LW (2023). Dysregulated RNA processing and metabolism: a new hallmark of ageing and provocation for cellular senescence.
FEBS J,
290(5), 1221-1234.
Abstract.
Author URL.
Turner J, Pound P, Owen C, Hutchinson I, Hop M, Chau DYS, Barrios Silva LV, Coleman M, Dubourg A, Harries LW, et al (2023). Incorporating new approach methodologies into regulatory nonclinical pharmaceutical safety assessment.
ALTEX,
40(3), 519-533.
Abstract.
Author URL.
Scott E, Archer Goode E, Garnham R, Hodgson K, Orozco-Moreno M, Turner H, Livermore K, Putri Nangkana K, Frame FM, Bermudez A, et al (2023). ST6GAL1-mediated aberrant sialylation promotes prostate cancer progression.
J Pathol,
261(1), 71-84.
Abstract.
Author URL.
Bramwell LR, Harries LW (2023). Senescence, regulators of alternative splicing and effects of trametinib treatment in progeroid syndromes.
GeroScience,
46(2), 1861-1879.
Abstract.
Scott E, Hodgson K, Calle B, Turner H, Cheung K, Bermudez A, Marques FJG, Pye H, Yo EC, Islam K, et al (2023). Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth.
Oncogene,
42(12), 926-937.
Abstract.
Author URL.
Kennedy NA, Janjua M, Chanchlani N, Lin S, Bewshea C, Nice R, McDonald TJ, Auckland C, Harries LW, Davies M, et al (2023). Vaccine escape, increased breakthrough and reinfection in infliximab-treated patients with IBD during the Omicron wave of the SARS-CoV-2 pandemic.
Gut,
72(2), 295-305.
Abstract.
Author URL.
Frankum R, Jameson TSO, Knight BA, Stephens FB, Wall BT, Donlon TA, Torigoe T, Willcox BJ, Willcox DC, Allsopp RC, et al (2022). Correction to: Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels.
Geroscience,
44(2), 1169-1170.
Author URL.
Mou Z, Spencer J, Knight B, John J, McCullagh P, McGrath JS, Harries LW (2022). Gene expression analysis reveals a 5-gene signature for progression-free survival in prostate cancer.
Frontiers in Oncology,
12 Abstract.
Davies M, Bramwell LR, Jeffery N, Bunce B, Lee BP, Knight B, Auckland C, Masoli JA, Harries LW (2022). Persistence of clinically relevant levels of SARS-CoV2 envelope gene subgenomic RNAs in non-immunocompromised individuals.
Int J Infect Dis,
116, 418-425.
Abstract.
Author URL.
Ammous Z, Rawlins LE, Jones H, Leslie JS, Wenger O, Scott E, Deline J, Herr T, Evans R, Scheid A, et al (2021). A biallelic SNIP1 Amish founder variant causes a recognizable neurodevelopmental disorder.
PLOS Genetics,
17(9), e1009803-e1009803.
Abstract.
Jeffery N, Chambers D, Invergo BM, Ames RM, Harries LW (2021). Changes to the identity of EndoC-βH1 beta cells may be mediated by stress-induced depletion of HNRNPD.
Cell & Bioscience,
11(1).
Abstract.
Frankum R, Jameson TSO, Knight BA, Stephens FB, Wall BT, Donlon TA, Torigoe T, Willcox BJ, Willcox DC, Allsopp RC, et al (2021). Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels.
GeroScience,
44(2), 1129-1140.
Abstract.
Lee BP, Harries LW (2021). Senotherapeutic Drugs: a New Avenue for Skincare?.
PLASTIC AND RECONSTRUCTIVE SURGERY,
148(6S), 21S-26S.
Author URL.
Bramwell LR, Harries LW (2021). Targeting Alternative Splicing for Reversal of Cellular Senescence in the Context of Aesthetic Aging.
Plast Reconstr Surg,
147(1S-2), 25S-32S.
Abstract.
Author URL.
Deane CS, Willis CRG, Phillips BE, Atherton PJ, Harries LW, Ames RM, Szewczyk NJ, Etheridge T (2021). Transcriptomic meta-analysis of disuse muscle atrophy vs. resistance exercise-induced hypertrophy in young and older humans.
J Cachexia Sarcopenia Muscle,
12(3), 629-645.
Abstract.
Author URL.
Kuo CL, Joaquim M, Kuchel GA, Ferrucci L, Harries LW, Pilling LC, Melzer D (2020). Erratum: the longevity-associated SH2B3 (LNK) genetic variant: selected aging phenotypes in 379,758 subjects (Journals of Gerontology - Series a Biological Sciences and Medical Sciences DOI: 10.1093/gerona/glz191).
Journals of Gerontology - Series a Biological Sciences and Medical Sciences,
75(9).
Abstract.
Haque S, Ames RM, Moore K, Lee BP, Jeffery N, Harries LW (2020). Islet-expressed circular RNAs are associated with type 2 diabetes status in human primary islets and in peripheral blood.
BMC Med Genomics,
13(1).
Abstract.
Author URL.
Lee BP, Smith M, Buffenstein R, Harries LW (2020). Negligible senescence in naked mole rats may be a consequence of well-maintained splicing regulation.
Geroscience,
42(2), 633-651.
Abstract.
Author URL.
Kuo C-L, Joaquim M, Kuchel GA, Ferrucci L, Harries LW, Pilling LC, Melzer D (2020). The Longevity-Associated SH2B3 (LNK) Genetic Variant: Selected Aging Phenotypes in 379,758 Subjects.
J Gerontol a Biol Sci Med Sci,
75(9), 1656-1662.
Abstract.
Author URL.
Calimport SRG, Bentley BL, Stewart CE, Pawelec G, Scuteri A, Vinciguerra M, Slack C, Chen D, Harries LW, Marchant G, et al (2020). The inherent challenges of classifying senescence−−Response. Science, 368(6491), 595-596.
Haque S, Ames RM, Moore K, Pilling LC, Peters LL, Bandinelli S, Ferrucci L, Harries LW (2020). circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan.
Geroscience,
42(1), 183-199.
Abstract.
Author URL.
Galvis D, Walsh D, Harries LW, Latorre E, Rankin J (2019). A dynamical systems model for the measurement of cellular senescence.
Journal of the Royal Society Interface,
16(159).
Abstract.
Latorre E, Mesonero JE, Harries LW (2019). Alternative splicing in serotonergic system: Implications in neuropsychiatric disorders.
J Psychopharmacol,
33(11), 1352-1363.
Abstract.
Author URL.
Munkley J, Li L, Krishnan SRG, Hysenaj G, Scott E, Dalgliesh C, Oo HZ, Maia TM, Cheung K, Ehrmann I, et al (2019). Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer.
Elife,
8 Abstract.
Author URL.
Lye JJ, Latorre E, Lee BP, Bandinelli S, Holley JE, Gutowski NJ, Ferrucci L, Harries LW (2019). Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14ARF, and TAU3 transcript expression and contribute to cognitive decline.
Geroscience,
41(5), 561-573.
Abstract.
Author URL.
Jeffery N, Richardson S, Chambers D, Morgan NG, Harries LW (2019). Cellular stressors may alter islet hormone cell proportions by moderation of alternative splicing patterns.
Hum Mol Genet,
28(16), 2763-2774.
Abstract.
Author URL.
Jeffery N, Harries LW (2019). Corrigendum to "miRNAs responsive to the diabetic microenvironment in the human beta cell line EndoC βH1 may target genes in the FOXO, HIPPO and Lysine degradation pathways" [Exp. Cell Res. 29 (2019) 111559].
Exp Cell Res,
385(1).
Author URL.
Lee BP, Mulvey L, Barr G, Garratt J, Goodman E, Selman C, Harries LW (2019). Dietary restriction in ILSXISS mice is associated with widespread changes in splicing regulatory factor expression levels.
Exp Gerontol,
128 Abstract.
Author URL.
Latorre E, Ostler EL, Faragher RGA, Harries LW (2019). FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence.
FASEB J,
33(1), 1086-1097.
Abstract.
Author URL.
Harries L (2019). It's time for scientists to shout about RNA therapies.
Nature,
574(7778).
Author URL.
Meerson A, Eliraz Y, Yehuda H, Knight B, Crundwell M, Ferguson D, Lee BP, Harries LW (2019). Obesity impacts the regulation of miR-10b and its targets in primary breast tumors.
BMC Cancer,
19(1).
Abstract.
Harries LW (2019). RNA Biology Provides New Therapeutic Targets for Human Disease.
FRONTIERS IN GENETICS,
10 Author URL.
Lee BP, Pilling LC, Bandinelli S, Ferrucci L, Melzer D, Harries LW (2019). The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
Biogerontology,
20(5), 649-663.
Abstract.
Author URL.
Calimport SRG, Bentley BL, Stewart CE, Pawelec G, Scuteri A, Vinciguerra M, Slack C, Chen D, Harries LW, Marchant G, et al (2019). To help aging populations, classify organismal senescence. Science, 366(6465), 576-578.
Jeffery N, Harries LW (2019). miRNAs responsive to the diabetic microenvironment in the human beta cell line EndoC-βH1 may target genes in the FOXO, HIPPO and Lysine degradation pathways.
Exp Cell Res,
384(1).
Abstract.
Author URL.
Ferguson DCJ, Smerdon GR, Harries LW, Dodd NJF, Murphy MP, Curnow A, Winyard PG (2018). Altered cellular redox homeostasis and redox responses under standard oxygen cell culture conditions versus physioxia.
Free Radic Biol Med,
126, 322-333.
Abstract.
Author URL.
Galloway T, Baglin N, Harries LW, Lee BP, Kocur AL, Shepherd M, Steele A, BPA Schools Study Consortium (2018). An engaged research study to assess the effect of a ‘real-world’ dietary intervention on urinary bisphenol a (BPA) levels in teenagers. BMJ Open, 8, e018742-e018742.
Clissold RL, Harries LW, Ellard S, Bingham C, Hattersley AT (2018). Comment on Dubois-Laforgue et al. Diabetes, Associated Clinical Spectrum, Long-term Prognosis, and Genotype/Phenotype Correlations in 201 Adult Patients with Hepatocyte Nuclear Factor 1B (HNF1B) Molecular Defects. Diabetes Care 2017;40:1436-1443.
Diabetes Care,
41(1).
Author URL.
Latorre E, Torregrossa R, Wood ME, Whiteman M, Harries LW (2018). Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2.
Aging (Albany NY),
10(7), 1666-1681.
Abstract.
Author URL.
Locke JM, Saint-Martin C, Laver TW, Patel KA, Wood AR, Sharp SA, Ellard S, Bellanné-Chantelot C, Hattersley AT, Harries LW, et al (2018). The Common HNF1A Variant I27L is a Modifier of Age at Diabetes Diagnosis in Individuals with HNF1A-MODY.
Diabetes,
67(9), 1903-1907.
Abstract.
Author URL.
Latorre E, Pilling LC, Lee BP, Bandinelli S, Melzer D, Ferrucci L, Harries LW (2018). The VEGFA156b isoform is dysregulated in senescent endothelial cells and may be associated with prevalent and incident coronary heart disease.
Clin Sci (Lond),
132(3), 313-325.
Abstract.
Author URL.
Harries L, Goljanek-Whysall K (2018). The biology of ageing and the omics revolution. Biogerontology, 19(6), 435-436.
Flanagan SE, Dũng VC, Houghton JAL, De Franco E, Ngoc CTB, Damhuis A, Ashcroft FM, Harries LW, Ellard S (2017). An ABCC8 Nonsense Mutation Causing Neonatal Diabetes Through Altered Transcript Expression.
J Clin Res Pediatr Endocrinol,
9(3), 260-264.
Abstract.
Author URL.
Haque S, Harries LW (2017). Circular RNAs (circRNAs) in Health and Disease.
Genes (Basel),
8(12).
Abstract.
Author URL.
Pilling LC, Kuo C-L, Sicinski K, Tamosauskaite J, Kuchel GA, Harries LW, Herd P, Wallace R, Ferrucci L, Melzer D, et al (2017). Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.
Aging (Albany NY),
9(12), 2504-2520.
Abstract.
Author URL.
Lee BP, Burić I, George-Pandeth A, Flurkey K, Harrison DE, Yuan R, Peters LL, Kuchel GA, Melzer D, Harries LW, et al (2017). MicroRNAs miR-203-3p, miR-664-3p and miR-708-5p are associated with median strain lifespan in mice.
Sci Rep,
7 Abstract.
Author URL.
Jeynes JCG, Geraki K, Jeynes C, Zhaohong M, Bettiol AA, Latorre E, Harries LW, Soeller C (2017). Nanoscale Properties of Human Telomeres Measured with a Dual Purpose X-ray Fluorescence and Super Resolution Microscopy Gold Nanoparticle Probe.
ACS Nano,
11(12), 12632-12640.
Abstract.
Author URL.
Pilling LC, Atkins JL, Duff MO, Beaumont RN, Jones SE, Tyrrell J, Kuo C-L, Ruth KS, Tuke MA, Yaghootkar H, et al (2017). Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
PLoS One,
12(9).
Abstract.
Author URL.
Latorre E, Birar VC, Sheerin AN, Jeynes JCC, Hooper A, Dawe HR, Melzer D, Cox LS, Faragher RGA, Ostler EL, et al (2017). Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence.
BMC Cell Biol,
18(1).
Abstract.
Author URL.
Latorre E, Harries LW (2017). Splicing regulatory factors, ageing and age-related disease.
Ageing Res Rev,
36, 165-170.
Abstract.
Author URL.
Munkley J, McClurg UL, Livermore KE, Ehrmann I, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, et al (2017). The cancer-associated cell migration protein TSPAN1 is under control of androgens and its upregulation increases prostate cancer cell migration.
Sci Rep,
7(1).
Abstract.
Author URL.
Jeffery N, Richardson S, Beall C, Harries LW (2017). The species origin of the cellular microenvironment influences markers of beta cell fate and function in EndoC-βH1 cells. Experimental Cell Research, 361(2), 284-291.
Lee BP, Pilling LC, Emond F, Flurkey K, Harrison DE, Yuan R, Peters LL, Kuchel GA, Ferrucci L, Melzer D, et al (2016). Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans.
Aging Cell,
15(5), 903-913.
Abstract.
Author URL.
Lee BP, Lloyd-Laney HO, Locke JM, McCulloch LJ, Knight B, Yaghootkar H, Cory G, Kos K, Frayling TM, Harries LW, et al (2016). Functional characterisation of ADIPOQ variants using individuals recruited by genotype.
Mol Cell Endocrinol,
428, 49-57.
Abstract.
Author URL.
Pilling LC, Joehanes R, Kacprowski T, Peters M, Jansen R, Karasik D, Kiel DP, Harries LW, Teumer A, Powell J, et al (2016). Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons.
Physiol Genomics,
48(1), 1-11.
Abstract.
Author URL.
Munkley J, Vodak D, Livermore KE, James K, Wilson BT, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, et al (2016). Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability.
EBioMedicine,
8, 103-116.
Abstract.
Pilling LC, Atkins JL, Bowman K, Jones SE, Tyrrell J, Beaumont RN, Ruth KS, Tuke MA, Yaghootkar H, Wood AR, et al (2016). Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.
Aging (Albany NY),
8(3), 547-560.
Abstract.
Author URL.
Atkins JL, Pilling LC, Ble A, Dutta A, Harries LW, Murray A, Brayne C, Robine J-M, Kuchel GA, Ferrucci L, et al (2016). Longer-Lived Parents and Cardiovascular Outcomes: 8-Year Follow-Up in 186,000 U.K. Biobank Participants.
J Am Coll Cardiol,
68(8), 874-875.
Author URL.
Chen BH, Hivert M-F, Peters MJ, Pilling LC, Hogan JD, Pham LM, Harries LW, Fox CS, Bandinelli S, Dehghan A, et al (2016). Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations.
Diabetes,
65(12), 3794-3804.
Abstract.
Author URL.
Tugay K, Guay C, Marques AC, Allagnat F, Locke JM, Harries LW, Rutter GA, Regazzi R (2016). Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets.
Diabetologia,
59(1), 161-169.
Abstract.
Tugay K, Guay C, Marques AC, Allagnat F, Locke JM, Harries LW, Rutter GA, Regazzi R (2016). Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets.
Diabetologia,
59(1), 161-169.
Abstract.
Author URL.
Kamenska A, Simpson C, Vindry C, Broomhead H, Bénard M, Ernoult-Lange M, Lee BP, Harries LW, Weil D, Standart N, et al (2016). The DDX6-4E-T interaction mediates translational repression and P-body assembly.
Nucleic Acids Res,
44(13), 6318-6334.
Abstract.
Author URL.
Jeffery N, Harries LW (2016). β-cell differentiation status in type 2 diabetes.
Diabetes Obes Metab,
18(12), 1167-1175.
Abstract.
Author URL.
Locke JM, Wei FY, Tomizawa K, Weedon MN, Harries LW (2015). A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1.
Diabetologia,
58(4), 745-748.
Abstract.
Locke JM, Wei F-Y, Tomizawa K, Weedon MN, Harries LW (2015). A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1.
Diabetologia,
58(4), 745-748.
Abstract.
Author URL.
Blackwell J, Harries LW, Pilling LC, Ferrucci L, Jones A, Melzer D (2015). Changes in CEBPB expression in circulating leukocytes following eccentric elbow-flexion exercise.
J Physiol Sci,
65(1), 145-150.
Abstract.
Author URL.
Holly AC, Grellscheid S, van de Walle P, Dolan D, Pilling LC, Daniels DJ, von Zglinicki T, Ferrucci L, Melzer D, Harries LW, et al (2015). Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts.
Biogerontology,
16(4), 423-434.
Abstract.
Author URL.
Pilling LC, Joehanes R, Melzer D, Harries LW, Henley W, Dupuis J, Lin H, Mitchell M, Hernandez D, Ying S-X, et al (2015). Gene expression markers of age-related inflammation in two human cohorts.
Exp Gerontol,
70, 37-45.
Abstract.
Author URL.
Galloway TS, Fletcher T, Thomas OJ, Lee BP, Pilling LC, Harries LW (2015). PFOA and PFOS are associated with reduced expression of the parathyroid hormone 2 receptor (PTH2R) gene in women.
Chemosphere,
120, 555-562.
Abstract.
Author URL.
Locke JM, Hysenaj G, Wood AR, Weedon MN, Harries LW (2015). Targeted allelic expression profiling in human islets identifies cis-regulatory effects for multiple variants identified by type 2 diabetes genome-wide association studies.
Diabetes,
64(4), 1484-1491.
Abstract.
Author URL.
Munkley J, Livermore KE, McClurg UL, Kalna G, Knight B, McCullagh P, McGrath J, Crundwell M, Leung HY, Robson CN, et al (2015). The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells.
Oncoscience,
2(9), 755-764.
Abstract.
Author URL.
Munkley J, Oltean S, Vodák D, Wilson BT, Livermore KE, Zhou Y, Star E, Floros VI, Johannessen B, Knight B, et al (2015). The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer.
Oncotarget,
6(33), 34358-34374.
Abstract.
Author URL.
Locke JM, Lango Allen H, Harries LW (2014). A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells.
Acta Diabetologica,
51(2), 325-329.
Abstract.
Locke JM, Lango Allen H, Harries LW (2014). A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells.
Acta Diabetol,
51(2), 325-329.
Abstract.
Author URL.
Cipelli R, Harries L, Okuda K, Yoshihara S, Melzer D, Galloway T (2014). Bisphenol a modulates the metabolic regulator oestrogen-related receptor-α in T-cells.
Reproduction,
147(4), 419-426.
Abstract.
Author URL.
Hogg DR, Harries LW (2014). Human genetic variation and its effect on miRNA biogenesis, activity and function.
Biochem Soc Trans,
42(4), 1184-1189.
Abstract.
Author URL.
Locke JM, Da Silva Xavier G, Dawe HR, Rutter GA, Harries LW (2014). Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion.
Diabetologia,
57(1), 122-128.
Abstract.
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, et al (2014). Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
Nat Neurosci,
17(9), 1164-1170.
Abstract.
Author URL.
Harries LW (2014). MicroRNAs as Mediators of the Ageing Process.
Genes (Basel),
5(3), 656-670.
Abstract.
Author URL.
Holly AC, Pilling LC, Hernandez D, Lee BP, Singleton A, Ferrucci L, Melzer D, Harries LW (2014). Splicing factor 3B1 hypomethylation is associated with altered SF3B1 transcript expression in older humans.
Mech Ageing Dev,
135, 50-56.
Abstract.
Author URL.
Harries LW, McCulloch LJ, Holley JE, Rawling TJ, Welters HJ, Kos K (2013). A role for SPARC in the moderation of human insulin secretion.
PLoS One,
8(6).
Abstract.
Author URL.
Harries LW, Pilling LC, Lampron A, Rivest S, Melzer D (2013). Alzheimer’s pathology: should peripheral monocytes and CCR2 take center stage?. Neurodegenerative Disease Management, 3(1), 9-12.
Fletcher T, Galloway TS, Melzer D, Holcroft P, Cipelli R, Pilling LC, Mondal D, Luster M, Harries LW (2013). Associations between PFOA, PFOS and changes in the expression of genes involved in cholesterol metabolism in humans.
Environ Int,
57-58, 2-10.
Abstract.
Author URL.
Holly AC, Melzer D, Pilling LC, Fellows AC, Tanaka T, Ferrucci L, Harries LW (2013). Changes in splicing factor expression are associated with advancing age in man.
Mech Ageing Dev,
134(9), 356-366.
Abstract.
Author URL.
Kendall AC, Whatmore JL, Harries LW, Winyard PG, Eggleton P, Smerdon GR (2013). Different oxygen treatment pressures alter inflammatory gene expression in human endothelial cells.
Undersea and Hyperbaric Medicine,
40(2), 115-123.
Abstract.
aer M, Jonathan L, Anna M, Lorna WH (2013). Expression profiling of putative type 2 diabetes susceptibility genes in human islets and in rat beta cell lines. Journal of Diabetes Mellitus, 03(01), 27-32.
Morrison F, Locke J, Arif M, Murray A, Brown JE, Harries LW (2013). Expression profiling of type 2 diabetes susceptibility genes in the pancreatic islets, adipose tissue and liver of obese mice.
Exp Clin Endocrinol Diabetes,
121(7), 413-419.
Abstract.
Author URL.
Melzer D, Pilling LC, Fellows AD, Holly AC, Harries LW, Ferrucci L (2013). Gene Expression Biomarkers and Longevity. Annual Review of Gerontology and Geriatrics, 33(1), 233-258.
Fellows AD, Holly AC, Pilling LC, Melzer D, Harries LW (2013). Microarray-based whole transcriptome expression profiling as a tool to understand human ageing.
, 209-220.
Abstract.
Morrison FS, Locke JM, Wood AR, Tuke M, Pasko D, Murray A, Frayling T, Harries LW (2013). The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts.
BMC Genomics,
14 Abstract.
Author URL.
Holly AC, Melzer D, Pilling LC, Henley W, Hernandez DG, Singleton AB, Bandinelli S, Guralnik JM, Ferrucci L, Harries LW, et al (2013). Towards a gene expression biomarker set for human biological age.
Aging Cell,
12(2), 324-326.
Abstract.
Harries LW, Fellows AD, Pilling LC, Hernandez D, Singleton A, Bandinelli S, Guralnik J, Powell J, Ferrucci L, Melzer D, et al (2012). Advancing age is associated with gene expression changes resembling mTOR inhibition: Evidence from two human populations.
Mechanisms of Ageing and Development,
133(8), 556-562.
Abstract.
Harries LW, Fellows AD, Pilling LC, Hernandez D, Singleton A, Bandinelli S, Guralnik J, Powell J, Ferrucci L, Melzer D, et al (2012). Advancing age is associated with gene expression changes resembling mTOR inhibition: evidence from two human populations.
Mech Ageing Dev,
133(8), 556-562.
Abstract.
Author URL.
Fellows AD, Holly AC, Pilling LC, Melzer D, Harries LW (2012). Age related changes in mTOR-related gene expression in two primary human cell lines. Healthy Aging Research
Harries LW, Pilling LC, Hernandez LDG, Bradley-Smith R, Henley W, Singleton AB, Guralnik JM, Bandinelli S, Ferrucci L, Melzer D, et al (2012). CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength.
Aging Cell,
11(2), 262-268.
Abstract.
Author URL.
Kendall AC, Whatmore JL, Harries LW, Winyard PG, Ferguson D, Eggleton P (2012). Different oxygen treatment pressures alter oxygen responses and redox signalling gene expression in human endothelial cells.
FREE RADICAL BIOLOGY AND MEDICINE,
53, S166-S166.
Author URL.
Melzer D, Harries L, Llewellyn DJ, Bandinelli S, Guralnik JM, Ferrucci L (2012). GENE EXPRESSION ASSOCIATIONS WITH MMSE SCORES: PHAGOCYTOSIS OF CNS BETA AMYLIOD?.
GERONTOLOGIST,
52, 453-453.
Author URL.
Pilling LC, Harries LW, Powell J, Llewellyn DJ, Ferrucci L, Melzer D (2012). Genomics and successful aging: grounds for renewed optimism?.
J Gerontol a Biol Sci Med Sci,
67(5), 511-519.
Abstract.
Author URL.
Harries LW, Bradley-Smith RM, Llewellyn DJ, Pilling LC, Fellows A, Henley W, Hernandez D, Guralnik JM, Bandinelli S, Singleton A, et al (2012). Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults.
Rejuvenation Res,
15(4), 395-404.
Abstract.
Author URL.
Harries LW (2012). Long non-coding RNAs and human disease.
Biochem Soc Trans,
40(4), 902-906.
Abstract.
Author URL.
Locke JM, Harries LW (2012). MicroRNA expression profiling of human islets from individuals with and without type 2 diabetes: promises and pitfalls.
Biochem Soc Trans,
40(4), 800-803.
Abstract.
Author URL.
Morrison F, Johnstone K, Murray A, Locke J, Harries LW (2012). Oxidative metabolism genes are not responsive to oxidative stress in rodent beta cell lines.
Experimental Diabetes Research,
2012 Abstract.
Garin I, de Nanclares GP, Gastaldo E, Harries LW, Rubio-Cabezas O, Castaño L (2012). Permanent neonatal diabetes caused by creation of an ectopic splice site within the INS gene.
PLoS ONE,
7(1).
Abstract.
Harries LW, Watura R (2012). Septic arthritis of unilateral lumbar facet joint with contiguous abscess, without prior intervention. Case Reports, 2012(apr02 1), bcr0920114849-bcr0920114849.
Wood AR, Hernandez DG, Nalls MA, Yaghootkar H, Gibbs JR, Harries LW, Chong S, Moore M, Weedon MN, Guralnik JM, et al (2011). Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association.
Hum Mol Genet,
20(20), 4082-4092.
Abstract.
Author URL.
Melzer D, Harries L, Cipelli R, Henley W, Money C, McCormack P, Young A, Guralnik J, Ferrucci L, Bandinelli S, et al (2011). Bisphenol a exposure is associated with in vivo estrogenic gene expression in adults.
Environ Health Perspect,
119(12), 1788-1793.
Abstract.
Author URL.
Harries LW, Melzer D, Cipelli R, Henley W, Money C, McCormack P, Young A, Guralnik J, Ferrucci L, Bandinelli S, et al (2011). Bisphenol a exposure is associated with in vivo estrogenic gene expression in adults.
Environ Health Perspect,
12(119), 1788-1793.
Abstract.
Melzer D, Harries L, Pilling L, Bandinelli S, Guralnik JM, Singleton A, Hernandez D, Ferrucci L (2011). CONFIRMATION OF MOUSE MODEL OF SARCOPENIA BY GENOME WIDE EXPRESSION STUDY IN HUMANS.
GERONTOLOGIST,
51, 506-507.
Author URL.
Kendall AC, Whatmore JL, Harries LW, Winyard PG, Smerdon GR, Eggleton P (2011). Changes in inflammatory gene expression induced by hyperbaric oxygen treatment in human endothelial cells under chronic wound conditions.
Experimental Cell Research Abstract.
GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group, Wellcome Trust Case Control Consortium 2, Zhou K, Bellenguez C, Spencer CCA, Bennett AJ, Coleman RL, Tavendale R, Hawley SA, Donnelly LA, et al (2011). Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.
Nat Genet,
43(2), 117-120.
Abstract.
Author URL.
Johnstone KA, Diakogiannaki E, Dhayal S, Morgan NG, Harries LW (2011). Dysregulation of Hnf1b gene expression in cultured beta-cells in response to cytotoxic fatty acid.
JOP,
12(1), 6-10.
Abstract.
Author URL.
Locke JM, Da Silva Xavier G, Rutter GA, Harries LW (2011). Erratum to: an alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes. Diabetologia, 1-1.
Locke JM, Da Silva Xavier G, Rutter GA, Harries LW (2011). Erratum to: an alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes. Diabetologia, 54(12).
Locke JM, Da Silva Xavier G, Rutter GA, Harries LW (2011). Erratum: an alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes (Diabetologia DOI: 10.1007/s00125-011-2290-6). Diabetologia, 54(12).
Harries LW, Hernandez D, Henley W, Wood AR, Holly AC, Bradley-Smith RM, Yaghootkar H, Dutta A, Murray A, Frayling TM, et al (2011). Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing.
Aging Cell,
10(5), 868-878.
Abstract.
Author URL.
Yaghootkar H, Hernandez D, Nalls M, Wood A, Gibbs R, Harries L, Chong S, Moore M, Guralnik J, Bandinell S, et al (2011). Identifying likely causal connections between gene expression levels using a Mendelian randomization approach.
CLINICAL BIOCHEMISTRY,
44(13), S294-S294.
Author URL.
Harries LW (2011). Messenger RNA processing and its role in diabetes.
Diabet Med,
28(9), 1010-1017.
Abstract.
Author URL.
Assam EE, Rhodes A, Ladomery M, Harries L, Sohail M (2011). Novel Alternative Splice Variants of HER2 in Invasive Breast Cancer.
CANCER RESEARCH,
71 Author URL.
Morrison FS, Johnstone KA, Harries LW (2011). Physiological effects of type 2 diabetes on mRNA processing and gene expression.
Expert Review of Endocrinology and Metabolism,
6(2), 255-267.
Abstract.
Harries LW, Perry JRB, McCullagh P, Crundwell M (2010). Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer.
BMC Cancer,
10 Abstract.
Author URL.
Alexander HM, Young E, Harries LW, Joyner M, Newman P, Sarsfield P (2010). An unusual case of cyclin-D1-positive peripheral T cell lymphoma with a 11:14 translocation.
Journal of Hematopathology,
3(2), 77-81.
Abstract.
Eggleton P, Harries LW, Alberigo G, Wordsworth P, Viner N, Haigh R, Donnelly S, Jones HW, O Conner TWE, Thomson AER, et al (2010). Changes in apoptotic gene expression in lymphocytes from rheumatoid arthritis and systemic lupus erythematosus patients compared with healthy lymphocytes.
Journal of Clinical Immunology,
30(5), 649-658.
Abstract.
Tarr JM, Winyard PG, Haigh R, Viner N, Eggleton P (2010). Extracellular calreticulin accumulates in the joints of rheumatoid arthritis patients and inhibits FasL (CD95L) mediated apoptosis of T cells. Arthritis and Rheumatism, 62(10), 2919-2929.
Wirsing A, Johnstone KA, Harries LW, Ellard S, Ryffel GU, Stanik J, Gasperikova D, Klimes I, Murphy R (2010). Novel monogenic diabetes mutations in the P2 promoter of the HNF4A gene are associated with impaired function in vitro. Diabetic Medicine, 27(6), 631-635.
Garin I, Edghill EL, Akerman I, Rubio-Cabezas O, Rica I, Locke JM, Maestro MA, Alshaikh A, Bundak R, Del Castillo G, et al (2010). Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America,
107(7), 3105-3110.
Abstract.
Hanlon K, Harries LW, Ellard S, Rudin CE (2009). Evaluation of 13q14 status in multiple myeloma by digital single nucleotide polymorphism technology.
J Mol Diagn,
11(5), 450-457.
Abstract.
Author URL.
Hanlon K, Ellard S, Rudin CE, Thorne S, Davies T, Harries LW (2009). Evaluation of 13q14 status in patients with chronic lymphocytic leukemia using single nucleotide polymorphism-based techniques.
J Mol Diagn,
11(4), 298-305.
Abstract.
Author URL.
Adalat S, Woolf AS, Johnstone KA, Wirsing A, Harries LW, Long DA, Hennekam RC, Ledermann SE, Rees L, van't Hoff W, et al (2009). HNF1B mutations associate with hypomagnesemia and renal magnesium wasting.
J Am Soc Nephrol,
20(5), 1123-1131.
Abstract.
Author URL.
Bockenhauer D, Adalat S, Johnstone KA, Wirsing A, Harries LW, Long DA, Hennekam RC, Ledermann SE, Rees L, van't Hoff W, et al (2009). Hepatocyte Nuclear Factor 1B mutations are associated with hypomagnesemia and renal magnesium wasting.
PEDIATRIC NEPHROLOGY,
24(4), 885-885.
Author URL.
Hanlon K, Rudin CE, Harries LW (2009). Investigating the targets of MIR-15a and MIR-16-1 in patients with chronic lymphocytic leukemia (CLL).
PLoS One,
4(9).
Abstract.
Author URL.
Harries LW, Brown JE, Gloyn AL (2009). Species-specific differences in the expression of the HNF1A, HNF1B and HNF4A genes.
PLoS One,
4(11).
Abstract.
Author URL.
Flanagan SE, Clauin S, Bellanné-Chantelot C, de Lonlay P, Harries LW, Gloyn AL, Ellard S (2009). Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism.
Hum Mutat,
30(2), 170-180.
Abstract.
Author URL.
Locke JM, Ellard S, Norwood VF, Harries LW (2009). Variants in the isoform-specific coding regions of the <i>HNF1A, HNF4A</i> and <i>HNF1B</i> genes are not a common cause of familial, young-onset diabetes or renal cysts and diabetes (RCAD).
DIABETIC MEDICINE,
26(5), 570-570.
Author URL.
Harries LW, Sloman MJ, Sellers EA, Hattersley AT, Ellard S (2008). DIABETES SUSCEPTIBILITY IN THE CANADIAN OJI-CREE POPULATION IS MODERATED BY ABNORMAL mRNA PROCESSING OF HNF1A G319S TRANSCRIPTS.
Diabetes Abstract.
Harries LW, Sloman MJ, Sellers EAC, Hattersley AT, Ellard S (2008). Diabetes Susceptibility in the Canadian Oji-Cree Population is Moderated by Abnormal mRNA Processing of HNF1A G319S Transcripts. Diabetes, 57(7), 1978-1982.
Harries LW, Sloman MJ, Sellers EAC, Hattersley AT, Ellard S (2008). Diabetes susceptibility in the Canadian Oji-Cree population is moderated by abnormal mRNA processing of <i>HNF1A</i> G319S transcripts.
DIABETES,
57(7), 1978-1982.
Author URL.
Edghill EL, Oram RA, Owens M, Stals KL, Harries LW, Hattersley AT, Ellard S, Bingham C (2008). Hepatocyte nuclear factor-1beta gene deletions--a common cause of renal disease.
Nephrol Dial Transplant,
23(2), 627-635.
Abstract.
Author URL.
Shield JPH, Flanagan SE, Mackay DJ, Harries LW, Proks P, Girard C, Ashcroft FM, Temple IK, Ellard S (2008). Mosaic paternal uniparental isodisomy and an ABCC8 gene mutation in a patient with permanent neonatal diabetes and hemihypertrophy.
Diabetes,
57(1), 255-258.
Abstract.
Author URL.
Locke JM, Harries LW (2008). RNA processing and mRNA surveillance in monogenic diabetes.
Gene Regul Syst Bio,
2, 203-212.
Abstract.
Author URL.
Murphy R, Baptista J, Holly J, Umpleby AM, Ellard S, Harries LW, Crolla J, Cundy T, Hattersley AT (2008). Severe intrauterine growth retardation and atypical diabetes associated with a translocation breakpoint disrupting regulation of the insulin-like growth factor 2 gene.
J Clin Endocrinol Metab,
93(11), 4373-4380.
Abstract.
Author URL.
Harries LW, Locke JM, Shields B, Hanley NA, Hanley KP, Steele A, Njølstad PR, Ellard S, Hattersley AT (2008). The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of HNF4A isoforms from the P1 promoter during fetal development.
Diabetes,
57(6), 1745-1752.
Abstract.
Author URL.
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JRB, Elliott KS, Lango H, Rayner NW, et al (2007). A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.
Science,
316(5826), 889-894.
Abstract.
Author URL.
Melzer D, Frayling TM, Murray A, Hurst AJ, Harries LW, Song H, Khaw K, Luben R, Surtees PG, Bandinelli SS, et al (2007). A common variant of the p16(INK4a) genetic region is associated with physical function in older people.
Mech Ageing Dev,
128(5-6), 370-377.
Abstract.
Author URL.
Wolstencroft EC, Hanlon K, Harries LW, Standen GR, Sternberg A, Ellard S (2007). Development of a quantitative real-time polymerase chain reaction assay for the detection of the JAK2 V617F mutation.
J Mol Diagn,
9(1), 42-46.
Abstract.
Author URL.
Locke JM, Harries LW, Sloman MJ, Sellers EA, Hattersley AT, Ellard S (2007). Diabetes susceptibility in the Canadian Oji-Cree population may be moderated by abnormal mRNA processing of <i>HNFIA</i> G319S transcripts.
DIABETIC MEDICINE,
24, 36-36.
Author URL.
Singh R, Edghill E, Bingham C, Ellard S, Hattersley AT, Harries LW (2007). Low prevalence of mitochondrial DNA 3243A>G point mutation in Caucasians with unexplained renal disease.
Diabet Med,
24(7), 804-806.
Author URL.
Edghill EL, Gloyn AL, Goriely A, Harries LW, Flanagan SE, Rankin J, Hattersley AT, Ellard S (2007). Origin of de novo KCNJ11 mutations and risk of neonatal diabetes for subsequent siblings.
J Clin Endocrinol Metab,
92(5), 1773-1777.
Abstract.
Author URL.
Ellard S, Thomas K, Edghill EL, Owens M, Ambye L, Cropper J, Little J, Strachan M, Stride A, Ersoy B, et al (2007). Partial and whole gene deletion mutations of the GCK and HNF1A genes in maturity-onset diabetes of the young.
Diabetologia,
50(11), 2313-2317.
Abstract.
Author URL.
Ellard S, Flanagan SE, Girard CA, Patch A-M, Harries LW, Parrish A, Edghill EL, Mackay DJG, Proks P, Shimomura K, et al (2007). Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects.
Am J Hum Genet,
81(2), 375-382.
Abstract.
Author URL.
Singh R, Hattersley AT, Harries LW (2007). Reduced peripheral blood mitochondrial DNA content is not a risk factor for Type 2 diabetes.
Diabet Med,
24(7), 784-787.
Abstract.
Author URL.
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JRB, Rayner NW, Freathy RM, et al (2007). Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
Science,
316(5829), 1336-1341.
Abstract.
Author URL.
Harries LW (2006). Alternate mRNA processing of the hepatocyte nuclear factor genes and its role in monogenic diabetes.
Expert Rev Endocrinol Metab,
1(6), 715-726.
Abstract.
Author URL.
Welters HJ, Senkel S, Klein-Hitpass L, Erdmann S, Thomas H, Harries LW, Pearson ER, Bingham C, Hattersley AT, Ryffel GU, et al (2006). Conditional expression of hepatocyte nuclear factor-1beta, the maturity-onset diabetes of the young-5 gene product, influences the viability and functional competence of pancreatic beta-cells.
J Endocrinol,
190(1), 171-181.
Abstract.
Author URL.
Harries LW, Ellard S, Stride A, Morgan NG, Hattersley AT (2006). Isomers of the TCF1 gene encoding hepatocyte nuclear factor-1 alpha show differential expression in the pancreas and define the relationship between mutation position and clinical phenotype in monogenic diabetes.
Hum Mol Genet,
15(14), 2216-2224.
Abstract.
Author URL.
Wickham CL, Harries LW, Sarsfield P, Joyner MV, Ellard S (2006). Large variation in t(11;14)(q13;q32) and t(14;18)(q32;q21) translocation product size is confirmed by sequence analysis of PCR products.
Clin Lab Haematol,
28(4), 248-253.
Abstract.
Author URL.
Singh R, Ellard S, Hattersley A, Harries LW (2006). Rapid and sensitive real-time polymerase chain reaction method for detection and quantification of 3243A>G mitochondrial point mutation.
J Mol Diagn,
8(2), 225-230.
Abstract.
Author URL.
Harries LW, Wickham CL, Evans JC, Rule SA, Joyner MV, Ellard S (2005). Analysis of haematopoietic chimaerism by quantitative real-time polymerase chain reaction.
Bone Marrow Transplant,
35(3), 283-290.
Abstract.
Author URL.
Harries LW, Bingham C, Bellanne-Chantelot C, Hattersley AT, Ellard S (2005). The position of premature termination codons in the hepatocyte nuclear factor -1 beta gene determines susceptibility to nonsense-mediated decay.
Hum Genet,
118(2), 214-224.
Abstract.
Author URL.
Theron T, Fousteri MI, Volker M, Harries LW, Botta E, Stefanini M, Fujimoto M, Andressoo J-O, Mitchell J, Jaspers NGJ, et al (2005). Transcription-associated breaks in xeroderma pigmentosum group D cells from patients with combined features of xeroderma pigmentosum and Cockayne syndrome.
Mol Cell Biol,
25(18), 8368-8378.
Abstract.
Author URL.
Harries LW, Ellard S, Jones RWA, Hattersley AT, Bingham C (2004). Abnormal splicing of hepatocyte nuclear factor-1 beta in the renal cysts and diabetes syndrome.
Diabetologia,
47(5), 937-942.
Abstract.
Author URL.
Harries LW, Hattersley AT, Ellard S (2004). Messenger RNA transcripts of the hepatocyte nuclear factor-1alpha gene containing premature termination codons are subject to nonsense-mediated decay.
Diabetes,
53(2), 500-504.
Abstract.
Author URL.
Gloyn AL, Cummings EA, Edghill EL, Harries LW, Scott R, Costa T, Temple IK, Hattersley AT, Ellard S (2004). Permanent neonatal diabetes due to paternal germline mosaicism for an activating mutation of the KCNJ11 Gene encoding the Kir6.2 subunit of the beta-cell potassium adenosine triphosphate channel.
J Clin Endocrinol Metab,
89(8), 3932-3935.
Abstract.
Author URL.
Bulman MP, Harries LW, Hansen T, Shepherd M, Kelly WF, Hattersley AT, Ellard S (2002). Abnormal splicing of hepatocyte nuclear factor 1 alpha in maturity-onset diabetes of the young.
Diabetologia,
45(10), 1463-1467.
Abstract.
Author URL.
Smith G, Stubbins MJ, Harries LW, Wolf CR (1998). Molecular genetics of the human cytochrome P450 monooxygenase superfamily.
Xenobiotica,
28(12), 1129-1165.
Author URL.
Matthias C, Bockmühl U, Jahnke V, Harries LW, Wolf CR, Jones PW, Alldersea J, Worrall SF, Hand P, Fryer AA, et al (1998). The glutathione S-transferase GSTP1 polymorphism: effects on susceptibility to oral/pharyngeal and laryngeal carcinomas.
Pharmacogenetics,
8(1), 1-6.
Abstract.
Author URL.
Ryberg D, Skaug V, Hewer A, Phillips DH, Harries LW, Wolf CR, Ogreid D, Ulvik A, Vu P, Haugen A, et al (1997). Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk.
Carcinogenesis,
18(7), 1285-1289.
Abstract.
Author URL.
Harries LW, Stubbins MJ, Forman D, Howard GC, Wolf CR (1997). Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer.
Carcinogenesis,
18(4), 641-644.
Abstract.
Author URL.
Stubbins MJ, Harries LW, Smith G, Tarbit MH, Wolf CR (1996). Genetic analysis of the human cytochrome P450 CYP2C9 locus.
Pharmacogenetics,
6(5), 429-439.
Abstract.
Author URL.
Abbott C, Malas S, Pilz A, Pate L, Ali R, Peters J (1994). Linkage mapping around the ragged (Ra) and wasted (wst) loci on distal mouse chromosome 2.
Genomics,
20(1), 94-98.
Abstract.
Author URL.