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Professor William Henley

Professor William Henley

Professor of Medical Statistics

6088

William Henley is Professor of Medical Statistics at the University of Exeter Medical School. He leads medical statistics across the Medical School, and is Head of the Health Statistics Group.

Qualifications

  • BA (Hons) Mathematics (University of Oxford)
  • MSc Statistics with Applications in Medicine (University of Southampton)
  • PhD Applied Statistics (The Open University)

Career

William has worked as an applied statistician for over 20 years and has broad experience of statistical consultancy in academia and industry. He received his undergraduate training in Mathematics at the University of Oxford, before studying for a PhD at the Open University on statistical methods for credit scoring, under the supervision of Professor David Hand. William has held postdoctoral positions in statistical epidemiology at the University of Oxford and the Animal Health Trust. Prior to joining the University of Exeter, he was Associate Professor (Reader) in Statistics in the Centre for Health and Environmental Statistics at Plymouth University. In 2010, he was seconded to the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care for the South West Peninsula (PenCLAHRC). He was appointed to a Chair in Medical Statistics at UEMS in May 2012.

Research

Research interests

  • Analysis of longitudinal, multilevel and survival data
  • Quasi-experimental analytic methods for strengthening causal inference from observational studies
  • Design and analysis of cohort and other epidemiological studies
  • Epidemiology of ageing, disability and chronic disease
  • Statistical methods in bioinformatics

A current focus of his research is on the development and application of methodology for evaluating medical treatments using observational patient data. His collaborations include providing statistical leadership for the Exeter component of the Healthy Ageing theme of the NIHR National School for Public Health. Another growing area of research interest is the development of a statistical framework for treatment stratification for chronic diseases such as type 2 diabetes.

Prof Henley gives an overview of his research into ways of using data to measure the effectiveness and safety of medical treatments, in the video below. 

Key publications | Publications by category | Publications by year

Key publications


Henley WE, Anderson LJ, Wyatt KM, Nikolaou V, Anderson R, Logan S (2014). The NCS-LSD cohort study: a description of the methods and analyses used to assess the long-term effectiveness of enzyme replacement therapy and substrate reduction therapy in patients with lysosomal storage disorders. J Inherit Metab Dis, 37(6), 939-944. Abstract.  Author URL.
Lin NX, Logan GS, Henley WE (2013). Bias and sensitivity analysis when estimating treatment effects from the Cox Model with omitted covariates. Biometrics Full text.
Hoyle MW, Henley W (2011). Improved curve fits to summary survival data: application to economic evaluation of health technologies. BMC Med Res Methodol, 11 Abstract.  Author URL.  Full text.
Lang IA, Galloway TS, Scarlett A, Henley WE, Depledge M, Wallace RB, Melzer D (2008). Association of urinary bisphenol a concentration with medical disorders and laboratory abnormalities in adults. JAMA, 300(11), 1303-1310. Abstract.  Author URL.

Publications by category


Journal articles

Streeter AJ, Lin NX, Crathorne L, Haasova M, Hyde C, Melzer D, Henley W (In Press). Adjusting for unmeasured confounding in non-randomised longitudinal studies: a methodological review. Journal of Clinical Epidemiology Full text.
Rodgers LR, weedon MN, Henley WE, Hattersley AT, Shields BM (In Press). Cohort profile for the MASTERMIND study: Using the Clinical Practice Research Datalink (CPRD) to investigate stratification of response to treatment in patients with Type 2 diabetes. BMJ Open Full text.
Zirk-Sadowski J, Masoli J, Strain WD, Delgado J, Henley W, Hamilton W, Melzer D, Ble A (In Press). Proton-Pump Inhibitors and Fragility Fractures in Vulnerable Older Patients. The American Journal of Gastroenterology (Elsevier) Full text.
Ford TJ, Parker C, Salim J, Goodman R, Logan S, Henley W (In Press). The Relationship between Exclusion from School and Mental Health: a Secondary Analysis of the British Child and Adolescent Mental Health Surveys 2004 and 2007. Psychological Medicine Full text.
Ford TJ, Paget A, Parker C, Heron J, Logan S, Henley W, EMOMND A (In Press). Which children and young people are excluded from school? Findings from a large British birth cohort study, the Avon Longitudinal Study of Parents and Children (ALSPAC). Child: Care, Health and Development Full text.
Allard J, Shankar R, Henley W, Brown A, McLean B, Jadav M, Parrett M, Laugharne R, Noble AJ, Ridsdale L, et al (2017). Frequency and factors associated with emergency department attendance for people with epilepsy in a rural UK population. Epilepsy and Behavior, 68, 192-195. Abstract.
Burt J, Campbell J, Abel G, Aboulghate A, Ahmed F, Asprey A, Barry H, Beckwith J, Benson J, Boiko O, et al (2017). Improving patient experience in primary care: a multimethod programme of research on the measurement and improvement of patient experience. Programme Grants for Applied Research, 5(9), 1-452. Full text.
Alsubaie M, Abbbott R, Dunn BD, Dickens C, Keil T, Henley W, Kuyken W (2017). Mechanisms of action in mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) in people with physical and/or psychological conditions: a systematic review. Clinical Psychology Review Full text.
Bowman K, Delgado J, Henley WE, Masoli JA, Kos K, Brayne C, Thokala P, Lafortune L, Kuchel GA, Ble A, et al (2017). Obesity in Older People with and Without Conditions Associated with Weight Loss: Follow-up of 955,000 Primary Care Patients. J Gerontol a Biol Sci Med Sci, 72(2), 203-209. Abstract.  Author URL.  Full text.
Shankar R, Henley W, Wehner T, Wiggans C, McLean B, Pace A, Mohan M, Sadler M, Doran Z, Hudson S, et al (2017). Perampanel in the general population and in people with intellectual disability: Differing responses. Seizure, 49, 30-35. Abstract.  Author URL.  Full text.
Ble A, Hughes PM, Delgado J, Masoli JA, Bowman K, Zirk-Sadowski J, Mujica Mota RE, Henley WE, Melzer D (2017). Safety and Effectiveness of Statins for Prevention of Recurrent Myocardial Infarction in 12 156 Typical Older Patients: a Quasi-Experimental Study. J Gerontol a Biol Sci Med Sci, 72(2), 243-250. Abstract.  Author URL.  Full text.
Pettit S, Qureshi A, Lee W, Stirzaker A, Gibson A, Henley W, Byng R (2017). Variation in referral and access to new psychological therapy services by age: an empirical quantitative study. Br J Gen Pract, 67(660), e453-e459. Abstract.  Author URL.
Pereira Gray D, Henley W, Chenore T, Sidaway-Lee K, Evans P (2017). What is the relationship between age and deprivation in influencing emergency hospital admissions? a model using data from a defined, comprehensive, all-age cohort in East Devon, UK. BMJ Open, 7(2). Abstract.  Author URL.  Full text.
Norman SM, Ford T, Henley W, Goodman R (2016). A comparison of parent reported outcome with experience of services. Journal of Children's Services, 11(2), 157-169. Abstract.  Full text.
Hunter JG, Madden RG, Stone AM, Osborne N, Wheeler B, Vine L, Dickson A, Barlow M, Lewis J, Bendall RP, et al (2016). Coastal clustering of HEV; Cornwall, UK. Eur J Gastroenterol Hepatol, 28(3), 323-327. Abstract.  Author URL.  Full text.
Mounce LTA, Barry HE, Calitri R, Henley WE, Campbell J, Roland M, Richards S (2016). Establishing the validity of English GP Patient Survey items evaluating out-of-hours care. BMJ Qual Saf, 25(11), 842-850. Abstract.  Author URL.  Full text.
Ruth KS, Perry JRB, Henley WE, Melzer D, Weedon MN, Murray A (2016). Events in Early Life are Associated with Female Reproductive Ageing: a UK Biobank Study. Sci Rep, 6 Abstract.  Author URL.  Full text.
Pilling LC, Joehanes R, Kacprowski T, Peters M, Jansen R, Karasik D, Kiel DP, Harries LW, Teumer A, Powell J, et al (2016). Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. Physiol Genomics, 48(1), 1-11. Abstract.  Author URL.  Full text.
Lin NX, Henley WE (2016). Prior event rate ratio adjustment for hidden confounding in observational studies of treatment effectiveness: a pairwise Cox likelihood approach. Statistics in Medicine, 35(28), 5149-5169. Abstract.  Full text.
Eyre V, Lang CC, Smith K, Jolly K, Davis R, Hayward C, Wingham J, Abraham C, Green C, Warren FC, et al (2016). Rehabilitation Enablement in Chronic Heart Failure-a facilitated self-care rehabilitation intervention in patients with heart failure with preserved ejection fraction (REACH-HFpEF) and their caregivers: rationale and protocol for a single-centre pilot randomised controlled trial. BMJ Open, 6(10). Abstract.  Author URL.  Full text.
Jones AG, Lonergan M, Henley WE, Pearson ER, Hattersley AT, Shields BM (2016). Should Studies of Diabetes Treatment Stratification Correct for Baseline HbA1c?. PLoS One, 11(4). Abstract.  Author URL.  Full text.
Abel A, Hayes AM, Henley W, Kuyken W (2016). Sudden gains in cognitive-behavior therapy for treatment-resistant depression: Processes of change. J Consult Clin Psychol, 84(8), 726-737. Abstract.  Author URL.
Parker C, Marlow R, Kastner M, May F, Mitrofan O, Henley W, Ford T (2016). The "supporting kids, avoiding problems" (SKIP) study: Relationships between school exclusion, psychopathology, development and attainment - Case control study. Journal of Children's Services, 11(2), 91-110. Abstract.  Full text.
Kuźma E, Soni M, Littlejohns TJ, Ranson JM, van Schoor NM, Deeg DJH, Comijs H, Chaves PHM, Kestenbaum BR, Kuller LH, et al (2016). Vitamin D and Memory Decline: Two Population-Based Prospective Studies. J Alzheimers Dis, 50(4), 1099-1108. Abstract.  Author URL.  Full text.
Littlejohns TJ, Kos K, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Kestenbaum BR, Kuller LH, Langa KM, et al (2016). Vitamin D and Risk of Neuroimaging Abnormalities. PLoS One, 11(5). Abstract.  Author URL.  Full text.
Ble A, Masoli JAH, Barry HE, Winder RE, Tavakoly B, Henley WE, Kuchel GA, Valderas JM, Melzer D, Richards SH, et al (2015). Any versus long-term prescribing of high risk medications in older people using 2012 Beers Criteria: results from three cross-sectional samples of primary care records for 2003/4, 2007/8 and 2011/12. BMC Geriatr, 15 Abstract.  Author URL.  Full text.
Steel N, Hardcastle AC, Bachmann MO, Richards SH, Mounce LTA, Clark A, Lang I, Melzer D, Campbell JL (2015). Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study. BMJ Open, 4(10). Abstract.  Full text.
Metcalf BS, Hosking J, Henley WE, Jeffery AN, Mostazir M, Voss LD, Wilkin TJ (2015). Erratum to: Physical activity attenuates the mid-adolescent peak in insulin resistance but by late adolescence the effect is lost: a longitudinal study with annual measures from 9-16 years (EarlyBird 66). Diabetologia, 58(12). Author URL.
Metcalf BS, Hosking J, Jeffery AN, Henley WE, Wilkin TJ (2015). Exploring the Adolescent Fall in Physical Activity: a 10-yr Cohort Study (EarlyBird 41). Med Sci Sports Exerc, 47(10), 2084-2092. Abstract.  Author URL.  Full text.
Williams AJ, Wyatt KM, Williams CA, Logan S, Henley WE (2015). Exploring the Potential of a School Impact on Pupil Weight Status: Exploratory Factor Analysis and Repeat Cross-Sectional Study of the National Child Measurement Programme. PLoS One, 10(12). Abstract.  Author URL.  Full text.
Pilling LC, Joehanes R, Melzer D, Harries LW, Henley W, Dupuis J, Lin H, Mitchell M, Hernandez D, Ying S-X, et al (2015). Gene expression markers of age-related inflammation in two human cohorts. Exp Gerontol, 70, 37-45. Abstract.  Author URL.
Melzer D, Tavakoly B, Winder RE, Masoli JAH, Henley WE, Ble A, Richards SH (2015). Much more medicine for the oldest old: trends in UK electronic clinical records. Age Ageing, 44(1), 46-53. Abstract.  Author URL.  Full text.
Mounce LTA, Steel N, Hardcastle AC, Henley WE, Bachmann MO, Campbell JL, Melzer D, Richards SH (2015). Patient characteristics predicting failure to receive indicated care for type 2 diabetes. Diabetes Research and Clinical Practice, 107(2), 247-258. Abstract.  Full text.
Metcalf BS, Hosking J, Henley WE, Jeffery AN, Mostazir M, Voss LD, Wilkin TJ (2015). Physical activity attenuates the mid-adolescent peak in insulin resistance but by late adolescence the effect is lost: a longitudinal study with annual measures from 9-16 years (EarlyBird 66). Diabetologia, 58(12), 2699-2708. Abstract.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Cherubini A, Ferrucci L, Lang IA, Langa KM, Melzer D, Llewellyn DJ (2015). Serum leptin and risk of cognitive decline in elderly italians. J Alzheimers Dis, 44(4), 1231-1239. Abstract.  Author URL.  Full text.
Hardcastle AC, Mounce LTA, Richards SH, Bachmann MO, Clark A, Henley WE, Campbell JL, Melzer D, Steel N (2015). The dynamics of quality: a national panel study of evidence-based standards. Health Services and Delivery Research, 3(11), 1-128. Full text.
Ble A, Delgado J, Bowman K, Masoli JA, Streeter A, Henley W, Melzer D (2015). USING ELECTRONIC MEDICAL RECORDS TO ESTIMATE THE EFFECTIVENESS OF STATINS IN PREVENTING CARDIOVASCULAR DISEASE AND ALL-CAUSE MORTALITY IN PEOPLE 75 AND OLDER. GERONTOLOGIST, 55, 26-26. Author URL.
Delgado J, Ble A, Bowman K, Masoli JA, Streeter A, Henley W, Melzer D (2015). USING ELECTRONIC MEDICAL RECORDS TO ESTIMATE THE EFFECTIVENESS OF STATINS IN PREVENTING THE INCIDENCE\ ONSET OF DEMENTIA IN PEOPLE 75 AND OLDER. GERONTOLOGIST, 55, 26-26. Author URL.
Paget A, Parker C, Henley W, Heron J, Ford T, Emond A (2015). Which children and young people are excluded from school? Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC). Lancet, 385 Suppl 1 Abstract.  Author URL.  Full text.
Williams AJ, Wyatt KM, Williams CA, Logan S, Henley WE (2014). A repeated cross-sectional study examining the school impact on child weight status. Prev Med, 64, 103-107. Abstract.  Author URL.  Full text.
Dutta A, Henley W, Robine JM, Llewellyn D, Langa KM, Wallace RB, Melzer D (2014). Aging children of long-lived parents experience slower cognitive decline. Alzheimer's and Dementia, 10(5), S315-S322. Abstract.
Anderson LJ, Henley W, Wyatt KM, Nikolaou V, Waldek S, Hughes DA, Lachmann RH, Logan S (2014). Effectiveness of enzyme replacement therapy in adults with late-onset Pompe disease: results from the NCS-LSD cohort study. J Inherit Metab Dis, 37(6), 945-952. Abstract.  Author URL.
Jones AG, Shields BM, Hyde CJ, Henley WE, Hattersley AT (2014). Identifying good responders to glucose lowering therapy in type 2 diabetes: implications for stratified medicine. PLoS One, 9(10). Abstract.  Author URL.  Full text.
Last A, Henley W, Norman S, Goodman R, Ford T (2014). Innovations in Practice: Feasibility of the development and well-being assessment as an adjunct to clinical assessment in child and adolescent mental health services. Child and Adolescent Mental Health, 19(2), 142-146. Abstract.
Anderson LJ, Wyatt KM, Henley W, Nikolaou V, Waldek S, Hughes DA, Pastores GM, Logan S (2014). Long-term effectiveness of enzyme replacement therapy in Fabry disease: results from the NCS-LSD cohort study. J Inherit Metab Dis, 37(6), 969-978. Abstract.  Author URL.
Anderson LJ, Henley W, Wyatt KM, Nikolaou V, Hughes DA, Waldek S, Logan S (2014). Long-term effectiveness of enzyme replacement therapy in adults with Gaucher disease: results from the NCS-LSD cohort study. J Inherit Metab Dis, 37(6), 953-960. Abstract.  Author URL.
Anderson LJ, Henley W, Wyatt KM, Nikolaou V, Waldek S, Hughes DA, Pastores GM, Logan S (2014). Long-term effectiveness of enzyme replacement therapy in children with Gaucher disease: results from the NCS-LSD cohort study. J Inherit Metab Dis, 37(6), 961-968. Abstract.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Cherubini A, Ferrucci L, Lang IA, Langa KM, Melzer D, Llewellyn DJ (2014). SERUM LEPTIN AND RISK OF COGNITIVE DECLINE IN ELDERLY ITALIANS: a PROSPECTIVE COHORT STUDY. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 68, A4-A4. Author URL.
Steel N, Hardcastle AC, Clark A, Mounce LTA, Bachmann MO, Richards SH, Henley WE, Campbell JL, Melzer D (2014). Self-reported quality of care for older adults from 2004 to 2011: a cohort study. Age Ageing, 43(5), 716-720. Abstract.  Author URL.  Full text.
Henley WE, Anderson LJ, Wyatt KM, Nikolaou V, Anderson R, Logan S (2014). The NCS-LSD cohort study: a description of the methods and analyses used to assess the long-term effectiveness of enzyme replacement therapy and substrate reduction therapy in patients with lysosomal storage disorders. J Inherit Metab Dis, 37(6), 939-944. Abstract.  Author URL.
Zahra D, Qureshi A, Henley W, Taylor R, Quinn C, Pooler J, Hardy G, Newbold A, Byng R (2014). The work and social adjustment scale: reliability, sensitivity and value. Int J Psychiatry Clin Pract, 18(2), 131-138. Abstract.  Author URL.
Littlejohns TJ, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Fried L, Kestenbaum BR, Kuller LH, Langa KM, et al (2014). Vitamin D and the risk of dementia and Alzheimer disease. Neurology, 83(10), 920-928. Abstract.  Author URL.  Full text.
Tyrrell J, Melzer D, Henley W, Galloway TS, Osborne NJ (2013). Associations between socioeconomic status and environmental toxicant concentrations in adults in the USA: NHANES 2001-2010. Environ Int, 59, 328-335. Abstract.  Author URL.
Lin NX, Logan GS, Henley WE (2013). Bias and sensitivity analysis when estimating treatment effects from the Cox Model with omitted covariates. Biometrics Full text.
Lin NX, Logan S, Henley WE (2013). Bias and sensitivity analysis when estimating treatment effects from the cox model with omitted covariates. Biometrics, 69(4), 850-860. Abstract.
Ford T, Last A, Henley W, Norman S, Guglani S, Kelesidi K, Martin AM, Moran P, Latham-Cork H, Goodman R, et al (2013). Can standardized diagnostic assessment be a useful adjunct to clinical assessment in child mental health services? a randomized controlled trial of disclosure of the Development and Well-Being Assessment to practitioners. Social Psychiatry and Psychiatric Epidemiology, 48(4), 583-593. Abstract.
Harrison A, Scobie L, Crossan C, Parry R, Johnston P, Stratton J, Dickinson S, Ellis V, Hunter JG, Prescott OR, et al (2013). Hepatitis E seroprevalence in recipients of renal transplants or haemodialysis in southwest England: a case-control study. Journal of Medical Virology, 85(2), 266-271. Abstract.
Dutta A, Henley W, Robine J-M, Langa KM, Wallace RB, Melzer D (2013). Longer lived parents: protective associations with cancer incidence and overall mortality. J Gerontol a Biol Sci Med Sci, 68(11), 1409-1418. Abstract.  Author URL.
Metcalf B, Henley W, Wilkin T (2013). Republished research: effectiveness of intervention on physical activity of children: systematic review and meta-analysis of controlled trials with objectively measured outcomes (EarlyBird 54). Br J Sports Med, 47(4). Author URL.
Shields BM, Henley W, Besser REJ, Hattersley AT, Ludvigsson J (2013). Response to Comment on: Besser et al. Lessons from the Mixed-Meal Tolerance Test: Use of 90-Minute and Fasting C-Peptide in Pediatric Diabetes. Diabetes Care 2013;36:195-201. DIABETES CARE, 36(12), E222-E222. Author URL.
Williams AJ, Henley WE, Williams CA, Hurst AJ, Logan S, Wyatt KM (2013). Systematic review and meta-analysis of the association between childhood overweight and obesity and primary school diet and physical activity policies. International Journal of Behavioural Nutrition and Physical Activity, 10 Full text.
Mann J, Henley W, O'Mahen H, Ford T (2013). The reliability and validity of the Everyday Feelings Questionnaire in a clinical population. Journal of Affective Disorders, 148(2-3), 406-410. Abstract.
Holly AC, Melzer D, Pilling LC, Henley W, Hernandez DG, Singleton AB, Bandinelli S, Guralnik JM, Ferrucci L, Harries LW, et al (2013). Towards a gene expression biomarker set for human biological age. Aging Cell, 12(2), 324-326. Abstract.  Full text.
Dutta A, Henley W, Pilling LC, Wallace RB, Melzer D (2013). Uric acid measurement improves prediction of cardiovascular mortality in later life. J Am Geriatr Soc, 61(3), 319-326. Abstract.  Author URL.
Metcalf B, Henley W, Wilkin T (2012). Authors' reply to Symonds. BMJ, 345
Harries LW, Pilling LC, Hernandez LDG, Bradley-Smith R, Henley W, Singleton AB, Guralnik JM, Bandinelli S, Ferrucci L, Melzer D, et al (2012). CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength. Aging Cell, 11(2), 262-268. Abstract.  Author URL.  Full text.
Hartley C, Donaldson D, Smith KC, Henley W, Lewis TW, Blott S, Mellersh C, Barnett KC (2012). Congenital keratoconjunctivitis sicca and ichthyosiform dermatosis in 25 Cavalier King Charles spaniel dogs. Part I: clinical signs, histopathology, and inheritance. Vet Ophthalmol, 15(5), 315-326. Abstract.  Author URL.
Melzer D, Gates P, Osborn NJ, Henley WE, Cipelli R, Young A, Money C, McCormack P, Schofield P, Mosedale D, et al (2012). Correction: Urinary Bisphenol a Concentration and Angiography-Defined Coronary Artery Stenosis. PLoS One, 7(11). Abstract.  Author URL.
Metcalf B, Henley W, Wilkin T (2012). Effectiveness of intervention on physical activity of children: Systematic review and meta-analysis of controlled trials with objectively measured outcomes (EarlyBird 54). BMJ (Online), 345(7876). Abstract.  Full text.
Keane FE, Gompels M, Bendall RP, Drayton R, Jennings L, Black J, Baragwanath G, Lin NX, Henley WE, Ngui S-L, et al (2012). Hepatitis E virus coinfection in patients with HIV infection. HIV MEDICINE, 13(1), 83-88. Author URL.
Metcalf B, Henley W, Wilkin T (2012). Keeping the customer satisfied reply. BRITISH MEDICAL JOURNAL, 345 Author URL.
Harries LW, Bradley-Smith RM, Llewellyn DJ, Pilling LC, Fellows A, Henley W, Hernandez D, Guralnik JM, Bandinelli S, Singleton A, et al (2012). Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults. Rejuvenation Res, 15(4), 395-404. Abstract.  Author URL.  Full text.
Melzer D, Dutta A, Henley W, Langa K, Wallace RB, Robine J (2012). MIDDLE-AGED OFFSPRING OF LONG LIVED PARENTS IN HRS. GERONTOLOGIST, 52, 414-414. Author URL.
Wyatt K, Henley W, Anderson L, Anderson R, Nikolaou V, Stein K, Klinger L, Hughes D, Waldek S, Lachmann R, et al (2012). The effectiveness and cost-effectiveness of enzyme and substrate replacement therapies: a longitudinal cohort study of people with lysosomal storage disorders. HEALTH TECHNOLOGY ASSESSMENT, 16(39), V-+. Author URL.
Melzer D, Osborne NJ, Henley WE, Cipelli R, Young A, Money C, McCormack P, Luben R, Khaw K-T, Wareham NJ, et al (2012). Urinary bisphenol a concentration and risk of future coronary artery disease in apparently healthy men and women. Circulation, 125(12), 1482-1490. Abstract.  Author URL.  Full text.
Melzer D, Gates P, Osborne NJ, Henley WE, Cipelli R, Young A, Money C, McCormack P, Schofield P, Mosedale D, et al (2012). Urinary bisphenol a concentration and angiography-defined coronary artery stenosis. PLoS One, 7(8). Abstract.  Author URL.  Full text.
Goodwin VA, Richards SH, Henley W, Ewings P, Taylor AH, Campbell JL (2011). An exercise intervention to prevent falls in people with Parkinson's disease: a pragmatic randomised controlled trial. Journal of Neurology, Neurosurgery and Psychiatry, 82(11), 1232-1238. Abstract.  Full text.
Melzer D, Harries L, Cipelli R, Henley W, Money C, McCormack P, Young A, Guralnik J, Ferrucci L, Bandinelli S, et al (2011). Bisphenol a exposure is associated with in vivo estrogenic gene expression in adults. Environ Health Perspect, 119(12), 1788-1793. Abstract.  Author URL.  Full text.
Rice NE, Lang IA, Henley W, Melzer D (2011). Common health predictors of early retirement: findings from the English Longitudinal Study of Ageing. Age Ageing, 40(1), 54-61. Abstract.  Author URL.
Metcalf BS, Hosking J, Jeffery AN, Voss LD, Henley W, Wilkin TJ (2011). Fatness leads to inactivity, but inactivity does not lead to fatness: a longitudinal study in children (EarlyBird 45). Arch Dis Child, 96(10), 942-947. Abstract.  Author URL.
Dalton HR, Bendall RP, Rashid M, Ellis V, Ali R, Ramnarace R, Stableforth W, Headdon W, Abbott R, McLaughlin C, et al (2011). Host risk factors and autochthonous hepatitis E infection. Eur J Gastroenterol Hepatol, 23(12), 1200-1205. Abstract.  Author URL.
Harries LW, Hernandez D, Henley W, Wood AR, Holly AC, Bradley-Smith RM, Yaghootkar H, Dutta A, Murray A, Frayling TM, et al (2011). Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing. Aging Cell, 10(5), 868-878. Abstract.  Author URL.
Hoyle MW, Henley W (2011). Improved curve fits to summary survival data: application to economic evaluation of health technologies. BMC Med Res Methodol, 11 Abstract.  Author URL.  Full text.
Dutta A, Henley W, Lang I, Llewellyn D, Guralnik J, Wallace RB, Melzer D (2011). Predictors of extraordinary survival in the Iowa established populations for epidemiologic study of the elderly: cohort follow-up to "extinction". J Am Geriatr Soc, 59(6), 963-971. Abstract.  Author URL.
MacKichan F, Paterson C, Henley WE, Britten N (2011). Self-care in people with long term health problems: a community based survey. BMC Fam Pract, 12 Abstract.  Author URL.  Full text.
Dutta A, Henley W, Lang IA, Murray A, Guralnik J, Wallace RB, Melzer D (2011). The coronary artery disease-associated 9p21 variant and later life 20-year survival to cohort extinction. Circ Cardiovasc Genet, 4(5), 542-548. Abstract.  Author URL.
Melzer D, Rice N, Depledge MH, Henley WE, Galloway TS (2010). Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the U.S. National Health and Nutrition Examination Survey. Environ Health Perspect, 118(5), 686-692. Abstract.  Author URL.  Full text.
Melzer D, Rice NE, Lewis C, Henley WE, Galloway TS (2010). Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06. PLoS One, 5(1). Abstract.  Author URL.  Full text.
Rice NE, Lang IA, Henley W, Melzer D (2010). Baby boomers nearing retirement: the healthiest generation?. Rejuvenation Res, 13(1), 105-114. Abstract.  Author URL.
Hosking J, Henley W, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ (2010). Changes in resting energy expenditure and their relationship to insulin resistance and weight gain: a longitudinal study in pre-pubertal children (EarlyBird 17). Clin Nutr, 29(4), 448-452. Abstract.  Author URL.
Dalton HR, Bendall RP, Pritchard C, Henley W, Melzer D (2010). National mortality rates from chronic liver disease and consumption of alcohol and pig meat. Epidemiol Infect, 138(2), 174-182. Abstract.  Author URL.
Cluett C, Brayne C, Clarke R, Evans G, Matthews F, Rubinsztein DC, Huppert F, Llewellyn DJ, Rice N, Henley W, et al (2010). Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people. Neurobiol Aging, 31(9), 1563-1568. Abstract.  Author URL.
Murray RC, Deaton CM, Smith NC, Henley WE, Marlin DJ (2009). Neither age nor osteoarthritis is associated with synovial fluid antioxidant disturbance or depletion in the horse. Comparative Exercise Physiology, 6(3), 121-128. Abstract.
Parahyba MI, Stevens K, Henley W, Lang IA, Melzer D (2009). Reductions in disability prevalence among the highest income groups of older Brazilians. Am J Public Health, 99(1), 81-86. Abstract.  Author URL.
Cluett C, McDermott MM, Guralnik J, Ferrucci L, Bandinelli S, Miljkovic I, Zmuda JM, Li R, Tranah G, Harris T, et al (2009). The 9p21 myocardial infarction risk allele increases risk of peripheral artery disease in older people. Circ Cardiovasc Genet, 2(4), 347-353. Abstract.  Author URL.
Melzer D, Perry JRB, Hernandez D, Corsi A-M, Stevens K, Rafferty I, Lauretani F, Murray A, Gibbs JR, Paolisso G, et al (2008). A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet, 4(5). Abstract.  Author URL.  Full text.
Lang IA, Galloway TS, Scarlett A, Henley WE, Depledge M, Wallace RB, Melzer D (2008). Association of urinary bisphenol a concentration with medical disorders and laboratory abnormalities in adults. JAMA, 300(11), 1303-1310. Abstract.  Author URL.
Ellis J, Logan S, Pumphrey R, Tan HK, Henley W, Edwards V, Moy R, Gilbert R (2008). Inequalities in provision of the Disability Living Allowance for Down syndrome. Arch Dis Child, 93(1), 14-16. Abstract.  Author URL.
Edwards DS, Coyne K, Dawson S, Gaskell RM, Henley WE, Rogers K, Wood JLN (2008). Risk factors for time to diagnosis of feline upper respiratory tract disease in UK animal adoption shelters. Prev Vet Med, 87(3-4), 327-339. Abstract.  Author URL.
Ellis JM, Tan HK, Gilbert RE, Muller DPR, Henley W, Moy R, Pumphrey R, Ani C, Davies S, Edwards V, et al (2008). Supplementation with antioxidants and folinic acid for children with Down's syndrome: randomised controlled trial. BMJ, 336(7644), 594-597. Abstract.  Author URL.  Full text.
Blissitt KJ, Raisis AL, Adams VJ, Rogers KH, Henley WE, Young LE (2008). The effects of halothane and isoflurane on cardiovascular function in dorsally recumbent horses undergoing surgery. VETERINARY ANAESTHESIA AND ANALGESIA, 35(3), 208-219. Author URL.
Rafiq S, Frayling TM, Murray A, Hurst A, Stevens K, Weedon MN, Henley W, Ferrucci L, Bandinelli S, Corsi A-M, et al (2007). A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects. Genes Immun, 8(7), 552-559. Abstract.  Author URL.
Frayling TM, Rafiq S, Murray A, Hurst AJ, Weedon MN, Henley W, Bandinelli S, Corsi A-M, Ferrucci L, Guralnik JM, et al (2007). An interleukin-18 polymorphism is associated with reduced serum concentrations and better physical functioning in older people. J Gerontol a Biol Sci Med Sci, 62(1), 73-78. Abstract.  Author URL.
Rafiq S, Stevens K, Hurst AJ, Murray A, Henley W, Weedon MN, Bandinelli S, Corsi AM, Guralnik JM, Ferruci L, et al (2007). Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels. Genes Immun, 8(4), 344-351. Abstract.  Author URL.
Johnson MS, Martin MWS, Henley W (2007). Results of pacemaker implantation in 104 dogs. JOURNAL OF SMALL ANIMAL PRACTICE, 48(1), 4-11. Author URL.
Henley WE, Rogers K, Harkins L, Wood JLN (2006). A comparison of survival models for assessing risk of racehorse fatality. Prev Vet Med, 74(1), 3-20. Abstract.  Author URL.
Sparkes AH, Rogers K, Henley WE, Gunn-Moore DA, May JM, Gruffydd-Jones TJ, Bessant C (2006). A questionnaire-based study of gestation, parturition and neonatal mortality in pedigree breeding cats in the UK. J Feline Med Surg, 8(3), 145-157. Abstract.  Author URL.
Scase TJ, Edwards D, Miller J, Henley W, Smith K, Blunden A, Murphy S (2006). Canine mast cell tumors: correlation of apoptosis and proliferation markers with prognosis. J Vet Intern Med, 20(1), 151-158. Abstract.  Author URL.
Platt S, Freeman J, di Stefani A, Wieczorek L, Henley W (2006). Prevalence of unilateral and bilateral deafness in border collies and association with phenotype. J Vet Intern Med, 20(6), 1355-1362. Abstract.  Author URL.
Deaton CM, Brown-Feltner H, Henley WE, Roberts CA, Lekeux P, Schroter RC, Marlin DJ (2006). The effect of inspired gas density on pulmonary artery transmural pressure and exercise induced pulmonary haemorrhage. Equine veterinary journal. Supplement(36), 490-494. Abstract.
Raisis AL, Blissitt KJ, Henley W, Rogers K, Adams V, Young LE (2005). The effects of halothane and isoflurane on cardiovascular function in laterally recumbent horses. Br J Anaesth, 95(3), 317-325. Abstract.  Author URL.
Crouch CF, Daly J, Henley W, Hannant D, Wilkins J, Francis MJ (2005). The use of a systemic prime/mucosal boost strategy with an equine influenza ISCOM vaccine to induce protective immunity in horses. Veterinary Immunology and Immunopathology, 108(3-4), 345-355. Abstract.
Verheyen KLP, Henley WE, Price JS, Wood JLN (2005). Training-related factors associated with dorsometacarpal disease in young Thoroughbred racehorses in the UK. Equine Vet J, 37(5), 442-448. Abstract.  Author URL.
Wood JLN, Lakhani KH, Henley WE (2004). An epidemiological approach to prevention and control of three common heritable diseases in canine pedigree breeds in the United Kingdom. Vet J, 168(1), 14-27. Abstract.  Author URL.
Daly JM, Yates PJ, Newton JR, Park A, Henley W, Wood JLN, Davis-Poynter N, Mumford JA (2004). Evidence supporting the inclusion of strains from each of the two co-circulating lineages of H3N8 equine influenza virus in vaccines. Vaccine, 22(29-30), 4101-4109. Abstract.  Author URL.
Johnson MS, Martin M, Edwards D, French A, Henley W (2004). Pulmonic stenosis in dogs: Balloon dilation improves clinical outcome. Journal of Veterinary Internal Medicine, 18(5), 656-662. Abstract.
Park AW, Wood JLN, Daly JM, Newton JR, Glass K, Henley W, Mumford JA, Grenfell BT (2004). The effects of strain heterology on the epidemiology of equine influenza in a vaccinated population. Proc Biol Sci, 271(1548), 1547-1555. Abstract.  Author URL.
Edwards DS, Henley WE, Ely ER, Wood JLN (2004). Vaccination and ill-health in dogs: a lack of temporal association and evidence of equivalence. Vaccine, 22(25-26), 3270-3273. Abstract.  Author URL.
Edwards DS, Henley WE, Harding EF, Dobson JM, Wood JLN (2003). Breed incidence of lymphoma in a UK population of insured dogs. Vet Comp Oncol, 1(4), 200-206. Abstract.  Author URL.
Henley WE, Wood JLN (2003). One hundred and one Dalmatians - the importance of being 'Patch'?. Veterinary Journal, 166(2), 105-106.
Ghani AC, Henley WE, Donnelly CA, Mayer S, Anderson RM (2002). Response to comments on the comparison of the effectiveness of non-nucleoside reverse transcriptase inhibitor and protease inhibitor-containing regimens using observational databases [6]. AIDS, 16(2), 302-303.
Ghani AC, Henley WE, Donnelly CA, Mayer S, Anderson RM (2001). Comparison of the effectiveness of non-nucleoside reverse transcriptase inhibitor-containing and protease inhibitor-containing regimens using observational databases. AIDS, 15(9), 1133-1142. Abstract.
Hand DJ, Henley WE (1997). Statistical classification methods in consumer credit scoring: a review. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 160, 523-541. Author URL.
Henley WE, Hand DJ (1996). A k-nearest-neighbour classifier for assessing consumer credit risk. Journal of the Royal Statistical Society Series D: the Statistician, 45(1), 77-95. Abstract.
Hand DJ, Henley WE (1993). Can reject inference ever work?. IMA Journal of Management Mathematics, 5(1), 45-55. Abstract.

Conferences

Dennis JM, Henley WE, Weedon MN, Lonergan M, Rodgers LR, Jones AG, Sattar NA, Holman RR, Pearson ER, Hattersley AT, et al (2017). A calculator to predict durability of HbA(1c) response with DPP4 inhibitors, sulfonylureas and thiazolidinediones: a MASTERMIND precision medicine study.  Author URL.
Dennis JM, Shields BM, Henley WE, Knight BA, McDonald TJ, Hill AV, Weedon MN, Rodgers LR, Hattersley AT, Jones AG, et al (2017). Clinical markers of insulin resistance predict reduced glycaemic response with DPP4-inhibitors: a MASTERMIND stratified medicine study.  Author URL.
Dennis JM, Henley WE, Weedon M, Lonergan M, Jones AG, Sattar N, Holman RR, Pearson ER, Hattersley AT, Shields BM, et al (2017). Development of an online risk calculator to predict durability of good glycaemic control with sulfonylurea and thiazolidinedione therapy: a MASTERMIND stratified medicine study.  Author URL.
Shields BM, Dennis J, Henley W, Weedon M, Lonergan M, Rodgers L, Jones A, Sattar N, Holman R, Pearson E, et al (2017). Predictors of response to SGLT2-inhibitors and DPP4-inhibitors.  Author URL.
Shields B, Dennis J, Henley W, Weedon M, Lonergan M, Jones A, Sattar N, Holman R, Pearson E, Hattersley A, et al (2017). Predictors of response to SGLT2-inhibitors and DPP4-inhibitors: a MASTERMIND stratified medicine study.  Author URL.
Shields BM, Dennis JM, Henley W, Weedon M, Lonergan M, Rodgers L, Jones AG, Holman RR, Pearson ER, Hattersley AT, et al (2016). Personalising therapy in type 2 diabetes: the effect of BMI and sex on glycaemic response and side effects to sulphonylureas and thiazolidinediones.  Author URL.
Dennis JM, Hattersley AT, Henley WE, Jones AG, Pearson ER, Shields BM (2016). Stratification using gender and body mass index (BMI) can predict side-effect risk in people with Type 2 diabetes initiating thiazolidinediones but not sulphonylureas: a MASTERMIND study.  Author URL.  Full text.
Shields B, Dennis J, Rodgers L, Jones A, Lonergan M, Henley W, Holman R, Pearson E, Hattersley A, Consortium MASTERMIND, et al (2016). Stratification using gender and body mass index (BMI) results in better glycaemic control for longer: a MASTERMIND study.  Author URL.
Dennis JM, Hattersley AT, Weedon M, Angwin C, Rodgers L, Pearson ER, Henley WE, Shields BM (2015). Development of oedema is associated with an improved glycaemic response in patients initiating thiazolidinediones: a MASTERMIND study.  Author URL.  Full text.
Shields BM, Lonergan M, Dennis J, Jones A, Rogers L, Weedon M, Donnelly L, Holman R, Henley W, Pearson E, et al (2015). Patient characteristics are associated with treatment response to second line glucose lowering therapy: a MASTERMIND study.  Author URL.
Dennis JM, Hattersley AT, Weedon M, Angwin CD, Rodgers L, Pearson ER, Henley WE, Shields BM (2015). Patients who develop oedema on initiating thiazolidinedione therapy have an improved glycaemic response: a MASTERMIND study.  Author URL.  Full text.
Jones AG, Lonergan M, Rodgers LR, Henley WE, Pearson EW, Hattersley AT, Shields BM, Consortium M (2015). Studies of diabetes treatment stratification should correct for baseline HbA1c: a MASTERMIND study.  Author URL.
Masoli J, Winder R, Tavakoly B, Henley W, Ble A, Richards S, Melzer D (2014). OVERDIAGNOSING AND MISSING THE POINT?.  Author URL.
Hunter J, Madden R, Stone A, Osborne N, Wheeler B, Barlow M, Bendall R, Lin N, Henley W, Gaze W, et al (2012). HEPATITIS E (HEV) IN SOUTH WEST ENGLAND. GEOGRAPHICAL, ENVIRONMENTAL AND SOCIAL FACTORS: a CASE CONTROL STUDY.  Author URL.
Madden RG, Harrison A, Scobie L, Crossan C, Hunter JG, Parry R, Johnston P, Stratton J, Dickinson S, Bendall R, et al (2012). HEV IN RENAL TRANSPLANT AND HAEMODIALYSIS PATIENTS.  Author URL.
Madden RG, Hunter JG, Stone AM, Thornton C, Barlow M, Lewis J, Bendall R, Lin N, Henley W, Dalton HR, et al (2012). LOCALLY ACQUIRED HEPATITIS E. GEOGRAPHICAL CLUSTERING AND ENVIRONMENTAL FACTORS: a NESTED CASE CONTROL STUDY.  Author URL.

Publications by year


In Press

Streeter AJ, Lin NX, Crathorne L, Haasova M, Hyde C, Melzer D, Henley W (In Press). Adjusting for unmeasured confounding in non-randomised longitudinal studies: a methodological review. Journal of Clinical Epidemiology Full text.
Rodgers LR, weedon MN, Henley WE, Hattersley AT, Shields BM (In Press). Cohort profile for the MASTERMIND study: Using the Clinical Practice Research Datalink (CPRD) to investigate stratification of response to treatment in patients with Type 2 diabetes. BMJ Open Full text.
Zirk-Sadowski J, Masoli J, Strain WD, Delgado J, Henley W, Hamilton W, Melzer D, Ble A (In Press). Proton-Pump Inhibitors and Fragility Fractures in Vulnerable Older Patients. The American Journal of Gastroenterology (Elsevier) Full text.
Ford TJ, Parker C, Salim J, Goodman R, Logan S, Henley W (In Press). The Relationship between Exclusion from School and Mental Health: a Secondary Analysis of the British Child and Adolescent Mental Health Surveys 2004 and 2007. Psychological Medicine Full text.
Ford TJ, Paget A, Parker C, Heron J, Logan S, Henley W, EMOMND A (In Press). Which children and young people are excluded from school? Findings from a large British birth cohort study, the Avon Longitudinal Study of Parents and Children (ALSPAC). Child: Care, Health and Development Full text.

2017

Dennis JM, Henley WE, Weedon MN, Lonergan M, Rodgers LR, Jones AG, Sattar NA, Holman RR, Pearson ER, Hattersley AT, et al (2017). A calculator to predict durability of HbA(1c) response with DPP4 inhibitors, sulfonylureas and thiazolidinediones: a MASTERMIND precision medicine study.  Author URL.
Dennis JM, Shields BM, Henley WE, Knight BA, McDonald TJ, Hill AV, Weedon MN, Rodgers LR, Hattersley AT, Jones AG, et al (2017). Clinical markers of insulin resistance predict reduced glycaemic response with DPP4-inhibitors: a MASTERMIND stratified medicine study.  Author URL.
Dennis JM, Henley WE, Weedon M, Lonergan M, Jones AG, Sattar N, Holman RR, Pearson ER, Hattersley AT, Shields BM, et al (2017). Development of an online risk calculator to predict durability of good glycaemic control with sulfonylurea and thiazolidinedione therapy: a MASTERMIND stratified medicine study.  Author URL.
Allard J, Shankar R, Henley W, Brown A, McLean B, Jadav M, Parrett M, Laugharne R, Noble AJ, Ridsdale L, et al (2017). Frequency and factors associated with emergency department attendance for people with epilepsy in a rural UK population. Epilepsy and Behavior, 68, 192-195. Abstract.
Burt J, Campbell J, Abel G, Aboulghate A, Ahmed F, Asprey A, Barry H, Beckwith J, Benson J, Boiko O, et al (2017). Improving patient experience in primary care: a multimethod programme of research on the measurement and improvement of patient experience. Programme Grants for Applied Research, 5(9), 1-452. Full text.
Alsubaie M, Abbbott R, Dunn BD, Dickens C, Keil T, Henley W, Kuyken W (2017). Mechanisms of action in mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) in people with physical and/or psychological conditions: a systematic review. Clinical Psychology Review Full text.
Bowman K, Delgado J, Henley WE, Masoli JA, Kos K, Brayne C, Thokala P, Lafortune L, Kuchel GA, Ble A, et al (2017). Obesity in Older People with and Without Conditions Associated with Weight Loss: Follow-up of 955,000 Primary Care Patients. J Gerontol a Biol Sci Med Sci, 72(2), 203-209. Abstract.  Author URL.  Full text.
Shankar R, Henley W, Wehner T, Wiggans C, McLean B, Pace A, Mohan M, Sadler M, Doran Z, Hudson S, et al (2017). Perampanel in the general population and in people with intellectual disability: Differing responses. Seizure, 49, 30-35. Abstract.  Author URL.  Full text.
Shields BM, Dennis J, Henley W, Weedon M, Lonergan M, Rodgers L, Jones A, Sattar N, Holman R, Pearson E, et al (2017). Predictors of response to SGLT2-inhibitors and DPP4-inhibitors.  Author URL.
Shields B, Dennis J, Henley W, Weedon M, Lonergan M, Jones A, Sattar N, Holman R, Pearson E, Hattersley A, et al (2017). Predictors of response to SGLT2-inhibitors and DPP4-inhibitors: a MASTERMIND stratified medicine study.  Author URL.
Ble A, Hughes PM, Delgado J, Masoli JA, Bowman K, Zirk-Sadowski J, Mujica Mota RE, Henley WE, Melzer D (2017). Safety and Effectiveness of Statins for Prevention of Recurrent Myocardial Infarction in 12 156 Typical Older Patients: a Quasi-Experimental Study. J Gerontol a Biol Sci Med Sci, 72(2), 243-250. Abstract.  Author URL.  Full text.
Pettit S, Qureshi A, Lee W, Stirzaker A, Gibson A, Henley W, Byng R (2017). Variation in referral and access to new psychological therapy services by age: an empirical quantitative study. Br J Gen Pract, 67(660), e453-e459. Abstract.  Author URL.
Pereira Gray D, Henley W, Chenore T, Sidaway-Lee K, Evans P (2017). What is the relationship between age and deprivation in influencing emergency hospital admissions? a model using data from a defined, comprehensive, all-age cohort in East Devon, UK. BMJ Open, 7(2). Abstract.  Author URL.  Full text.

2016

Norman SM, Ford T, Henley W, Goodman R (2016). A comparison of parent reported outcome with experience of services. Journal of Children's Services, 11(2), 157-169. Abstract.  Full text.
Hunter JG, Madden RG, Stone AM, Osborne N, Wheeler B, Vine L, Dickson A, Barlow M, Lewis J, Bendall RP, et al (2016). Coastal clustering of HEV; Cornwall, UK. Eur J Gastroenterol Hepatol, 28(3), 323-327. Abstract.  Author URL.  Full text.
Mounce LTA, Barry HE, Calitri R, Henley WE, Campbell J, Roland M, Richards S (2016). Establishing the validity of English GP Patient Survey items evaluating out-of-hours care. BMJ Qual Saf, 25(11), 842-850. Abstract.  Author URL.  Full text.
Ruth KS, Perry JRB, Henley WE, Melzer D, Weedon MN, Murray A (2016). Events in Early Life are Associated with Female Reproductive Ageing: a UK Biobank Study. Sci Rep, 6 Abstract.  Author URL.  Full text.
Pilling LC, Joehanes R, Kacprowski T, Peters M, Jansen R, Karasik D, Kiel DP, Harries LW, Teumer A, Powell J, et al (2016). Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. Physiol Genomics, 48(1), 1-11. Abstract.  Author URL.  Full text.
Shields BM, Dennis JM, Henley W, Weedon M, Lonergan M, Rodgers L, Jones AG, Holman RR, Pearson ER, Hattersley AT, et al (2016). Personalising therapy in type 2 diabetes: the effect of BMI and sex on glycaemic response and side effects to sulphonylureas and thiazolidinediones.  Author URL.
Lin NX, Henley WE (2016). Prior event rate ratio adjustment for hidden confounding in observational studies of treatment effectiveness: a pairwise Cox likelihood approach. Statistics in Medicine, 35(28), 5149-5169. Abstract.  Full text.
Eyre V, Lang CC, Smith K, Jolly K, Davis R, Hayward C, Wingham J, Abraham C, Green C, Warren FC, et al (2016). Rehabilitation Enablement in Chronic Heart Failure-a facilitated self-care rehabilitation intervention in patients with heart failure with preserved ejection fraction (REACH-HFpEF) and their caregivers: rationale and protocol for a single-centre pilot randomised controlled trial. BMJ Open, 6(10). Abstract.  Author URL.  Full text.
Jones AG, Lonergan M, Henley WE, Pearson ER, Hattersley AT, Shields BM (2016). Should Studies of Diabetes Treatment Stratification Correct for Baseline HbA1c?. PLoS One, 11(4). Abstract.  Author URL.  Full text.
Dennis JM, Hattersley AT, Henley WE, Jones AG, Pearson ER, Shields BM (2016). Stratification using gender and body mass index (BMI) can predict side-effect risk in people with Type 2 diabetes initiating thiazolidinediones but not sulphonylureas: a MASTERMIND study.  Author URL.  Full text.
Shields B, Dennis J, Rodgers L, Jones A, Lonergan M, Henley W, Holman R, Pearson E, Hattersley A, Consortium MASTERMIND, et al (2016). Stratification using gender and body mass index (BMI) results in better glycaemic control for longer: a MASTERMIND study.  Author URL.
Abel A, Hayes AM, Henley W, Kuyken W (2016). Sudden gains in cognitive-behavior therapy for treatment-resistant depression: Processes of change. J Consult Clin Psychol, 84(8), 726-737. Abstract.  Author URL.
Parker C, Marlow R, Kastner M, May F, Mitrofan O, Henley W, Ford T (2016). The "supporting kids, avoiding problems" (SKIP) study: Relationships between school exclusion, psychopathology, development and attainment - Case control study. Journal of Children's Services, 11(2), 91-110. Abstract.  Full text.
Kuźma E, Soni M, Littlejohns TJ, Ranson JM, van Schoor NM, Deeg DJH, Comijs H, Chaves PHM, Kestenbaum BR, Kuller LH, et al (2016). Vitamin D and Memory Decline: Two Population-Based Prospective Studies. J Alzheimers Dis, 50(4), 1099-1108. Abstract.  Author URL.  Full text.
Littlejohns TJ, Kos K, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Kestenbaum BR, Kuller LH, Langa KM, et al (2016). Vitamin D and Risk of Neuroimaging Abnormalities. PLoS One, 11(5). Abstract.  Author URL.  Full text.

2015

Ble A, Masoli JAH, Barry HE, Winder RE, Tavakoly B, Henley WE, Kuchel GA, Valderas JM, Melzer D, Richards SH, et al (2015). Any versus long-term prescribing of high risk medications in older people using 2012 Beers Criteria: results from three cross-sectional samples of primary care records for 2003/4, 2007/8 and 2011/12. BMC Geriatr, 15 Abstract.  Author URL.  Full text.
Dennis JM, Hattersley AT, Weedon M, Angwin C, Rodgers L, Pearson ER, Henley WE, Shields BM (2015). Development of oedema is associated with an improved glycaemic response in patients initiating thiazolidinediones: a MASTERMIND study.  Author URL.  Full text.
Steel N, Hardcastle AC, Bachmann MO, Richards SH, Mounce LTA, Clark A, Lang I, Melzer D, Campbell JL (2015). Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study. BMJ Open, 4(10). Abstract.  Full text.
Metcalf BS, Hosking J, Henley WE, Jeffery AN, Mostazir M, Voss LD, Wilkin TJ (2015). Erratum to: Physical activity attenuates the mid-adolescent peak in insulin resistance but by late adolescence the effect is lost: a longitudinal study with annual measures from 9-16 years (EarlyBird 66). Diabetologia, 58(12). Author URL.
Metcalf BS, Hosking J, Jeffery AN, Henley WE, Wilkin TJ (2015). Exploring the Adolescent Fall in Physical Activity: a 10-yr Cohort Study (EarlyBird 41). Med Sci Sports Exerc, 47(10), 2084-2092. Abstract.  Author URL.  Full text.
Williams AJ, Wyatt KM, Williams CA, Logan S, Henley WE (2015). Exploring the Potential of a School Impact on Pupil Weight Status: Exploratory Factor Analysis and Repeat Cross-Sectional Study of the National Child Measurement Programme. PLoS One, 10(12). Abstract.  Author URL.  Full text.
Pilling LC, Joehanes R, Melzer D, Harries LW, Henley W, Dupuis J, Lin H, Mitchell M, Hernandez D, Ying S-X, et al (2015). Gene expression markers of age-related inflammation in two human cohorts. Exp Gerontol, 70, 37-45. Abstract.  Author URL.
Melzer D, Tavakoly B, Winder RE, Masoli JAH, Henley WE, Ble A, Richards SH (2015). Much more medicine for the oldest old: trends in UK electronic clinical records. Age Ageing, 44(1), 46-53. Abstract.  Author URL.  Full text.
Shields BM, Lonergan M, Dennis J, Jones A, Rogers L, Weedon M, Donnelly L, Holman R, Henley W, Pearson E, et al (2015). Patient characteristics are associated with treatment response to second line glucose lowering therapy: a MASTERMIND study.  Author URL.
Mounce LTA, Steel N, Hardcastle AC, Henley WE, Bachmann MO, Campbell JL, Melzer D, Richards SH (2015). Patient characteristics predicting failure to receive indicated care for type 2 diabetes. Diabetes Research and Clinical Practice, 107(2), 247-258. Abstract.  Full text.
Dennis JM, Hattersley AT, Weedon M, Angwin CD, Rodgers L, Pearson ER, Henley WE, Shields BM (2015). Patients who develop oedema on initiating thiazolidinedione therapy have an improved glycaemic response: a MASTERMIND study.  Author URL.  Full text.
Metcalf BS, Hosking J, Henley WE, Jeffery AN, Mostazir M, Voss LD, Wilkin TJ (2015). Physical activity attenuates the mid-adolescent peak in insulin resistance but by late adolescence the effect is lost: a longitudinal study with annual measures from 9-16 years (EarlyBird 66). Diabetologia, 58(12), 2699-2708. Abstract.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Cherubini A, Ferrucci L, Lang IA, Langa KM, Melzer D, Llewellyn DJ (2015). Serum leptin and risk of cognitive decline in elderly italians. J Alzheimers Dis, 44(4), 1231-1239. Abstract.  Author URL.  Full text.
Jones AG, Lonergan M, Rodgers LR, Henley WE, Pearson EW, Hattersley AT, Shields BM, Consortium M (2015). Studies of diabetes treatment stratification should correct for baseline HbA1c: a MASTERMIND study.  Author URL.
Hardcastle AC, Mounce LTA, Richards SH, Bachmann MO, Clark A, Henley WE, Campbell JL, Melzer D, Steel N (2015). The dynamics of quality: a national panel study of evidence-based standards. Health Services and Delivery Research, 3(11), 1-128. Full text.
Ble A, Delgado J, Bowman K, Masoli JA, Streeter A, Henley W, Melzer D (2015). USING ELECTRONIC MEDICAL RECORDS TO ESTIMATE THE EFFECTIVENESS OF STATINS IN PREVENTING CARDIOVASCULAR DISEASE AND ALL-CAUSE MORTALITY IN PEOPLE 75 AND OLDER. GERONTOLOGIST, 55, 26-26. Author URL.
Delgado J, Ble A, Bowman K, Masoli JA, Streeter A, Henley W, Melzer D (2015). USING ELECTRONIC MEDICAL RECORDS TO ESTIMATE THE EFFECTIVENESS OF STATINS IN PREVENTING THE INCIDENCE\ ONSET OF DEMENTIA IN PEOPLE 75 AND OLDER. GERONTOLOGIST, 55, 26-26. Author URL.
Paget A, Parker C, Henley W, Heron J, Ford T, Emond A (2015). Which children and young people are excluded from school? Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC). Lancet, 385 Suppl 1 Abstract.  Author URL.  Full text.

2014

Williams AJ, Wyatt KM, Williams CA, Logan S, Henley WE (2014). A repeated cross-sectional study examining the school impact on child weight status. Prev Med, 64, 103-107. Abstract.  Author URL.  Full text.
Dutta A, Henley W, Robine JM, Llewellyn D, Langa KM, Wallace RB, Melzer D (2014). Aging children of long-lived parents experience slower cognitive decline. Alzheimer's and Dementia, 10(5), S315-S322. Abstract.
Williams AJ (2014). Determination of school-based contextual factors and their associations with the prevalence of overweight and obese children.  Abstract.
Anderson LJ, Henley W, Wyatt KM, Nikolaou V, Waldek S, Hughes DA, Lachmann RH, Logan S (2014). Effectiveness of enzyme replacement therapy in adults with late-onset Pompe disease: results from the NCS-LSD cohort study. J Inherit Metab Dis, 37(6), 945-952. Abstract.  Author URL.
Jones AG, Shields BM, Hyde CJ, Henley WE, Hattersley AT (2014). Identifying good responders to glucose lowering therapy in type 2 diabetes: implications for stratified medicine. PLoS One, 9(10). Abstract.  Author URL.  Full text.
Last A, Henley W, Norman S, Goodman R, Ford T (2014). Innovations in Practice: Feasibility of the development and well-being assessment as an adjunct to clinical assessment in child and adolescent mental health services. Child and Adolescent Mental Health, 19(2), 142-146. Abstract.
Anderson LJ, Wyatt KM, Henley W, Nikolaou V, Waldek S, Hughes DA, Pastores GM, Logan S (2014). Long-term effectiveness of enzyme replacement therapy in Fabry disease: results from the NCS-LSD cohort study. J Inherit Metab Dis, 37(6), 969-978. Abstract.  Author URL.
Anderson LJ, Henley W, Wyatt KM, Nikolaou V, Hughes DA, Waldek S, Logan S (2014). Long-term effectiveness of enzyme replacement therapy in adults with Gaucher disease: results from the NCS-LSD cohort study. J Inherit Metab Dis, 37(6), 953-960. Abstract.  Author URL.
Anderson LJ, Henley W, Wyatt KM, Nikolaou V, Waldek S, Hughes DA, Pastores GM, Logan S (2014). Long-term effectiveness of enzyme replacement therapy in children with Gaucher disease: results from the NCS-LSD cohort study. J Inherit Metab Dis, 37(6), 961-968. Abstract.  Author URL.
Masoli J, Winder R, Tavakoly B, Henley W, Ble A, Richards S, Melzer D (2014). OVERDIAGNOSING AND MISSING THE POINT?.  Author URL.
Littlejohns TJ, Kos K, Henley WE, Cherubini A, Ferrucci L, Lang IA, Langa KM, Melzer D, Llewellyn DJ (2014). SERUM LEPTIN AND RISK OF COGNITIVE DECLINE IN ELDERLY ITALIANS: a PROSPECTIVE COHORT STUDY. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 68, A4-A4. Author URL.
Steel N, Hardcastle AC, Clark A, Mounce LTA, Bachmann MO, Richards SH, Henley WE, Campbell JL, Melzer D (2014). Self-reported quality of care for older adults from 2004 to 2011: a cohort study. Age Ageing, 43(5), 716-720. Abstract.  Author URL.  Full text.
Henley WE, Anderson LJ, Wyatt KM, Nikolaou V, Anderson R, Logan S (2014). The NCS-LSD cohort study: a description of the methods and analyses used to assess the long-term effectiveness of enzyme replacement therapy and substrate reduction therapy in patients with lysosomal storage disorders. J Inherit Metab Dis, 37(6), 939-944. Abstract.  Author URL.
Zahra D, Qureshi A, Henley W, Taylor R, Quinn C, Pooler J, Hardy G, Newbold A, Byng R (2014). The work and social adjustment scale: reliability, sensitivity and value. Int J Psychiatry Clin Pract, 18(2), 131-138. Abstract.  Author URL.
Littlejohns TJ, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Fried L, Kestenbaum BR, Kuller LH, Langa KM, et al (2014). Vitamin D and the risk of dementia and Alzheimer disease. Neurology, 83(10), 920-928. Abstract.  Author URL.  Full text.

2013

Tyrrell J, Melzer D, Henley W, Galloway TS, Osborne NJ (2013). Associations between socioeconomic status and environmental toxicant concentrations in adults in the USA: NHANES 2001-2010. Environ Int, 59, 328-335. Abstract.  Author URL.
Lin NX, Logan GS, Henley WE (2013). Bias and sensitivity analysis when estimating treatment effects from the Cox Model with omitted covariates. Biometrics Full text.
Lin NX, Logan S, Henley WE (2013). Bias and sensitivity analysis when estimating treatment effects from the cox model with omitted covariates. Biometrics, 69(4), 850-860. Abstract.
Ford T, Last A, Henley W, Norman S, Guglani S, Kelesidi K, Martin AM, Moran P, Latham-Cork H, Goodman R, et al (2013). Can standardized diagnostic assessment be a useful adjunct to clinical assessment in child mental health services? a randomized controlled trial of disclosure of the Development and Well-Being Assessment to practitioners. Social Psychiatry and Psychiatric Epidemiology, 48(4), 583-593. Abstract.
Harrison A, Scobie L, Crossan C, Parry R, Johnston P, Stratton J, Dickinson S, Ellis V, Hunter JG, Prescott OR, et al (2013). Hepatitis E seroprevalence in recipients of renal transplants or haemodialysis in southwest England: a case-control study. Journal of Medical Virology, 85(2), 266-271. Abstract.
Dutta A, Henley W, Robine J-M, Langa KM, Wallace RB, Melzer D (2013). Longer lived parents: protective associations with cancer incidence and overall mortality. J Gerontol a Biol Sci Med Sci, 68(11), 1409-1418. Abstract.  Author URL.
Metcalf B, Henley W, Wilkin T (2013). Republished research: effectiveness of intervention on physical activity of children: systematic review and meta-analysis of controlled trials with objectively measured outcomes (EarlyBird 54). Br J Sports Med, 47(4). Author URL.
Shields BM, Henley W, Besser REJ, Hattersley AT, Ludvigsson J (2013). Response to Comment on: Besser et al. Lessons from the Mixed-Meal Tolerance Test: Use of 90-Minute and Fasting C-Peptide in Pediatric Diabetes. Diabetes Care 2013;36:195-201. DIABETES CARE, 36(12), E222-E222. Author URL.
Williams AJ, Henley WE, Williams CA, Hurst AJ, Logan S, Wyatt KM (2013). Systematic review and meta-analysis of the association between childhood overweight and obesity and primary school diet and physical activity policies. International Journal of Behavioural Nutrition and Physical Activity, 10 Full text.
Mann J, Henley W, O'Mahen H, Ford T (2013). The reliability and validity of the Everyday Feelings Questionnaire in a clinical population. Journal of Affective Disorders, 148(2-3), 406-410. Abstract.
Holly AC, Melzer D, Pilling LC, Henley W, Hernandez DG, Singleton AB, Bandinelli S, Guralnik JM, Ferrucci L, Harries LW, et al (2013). Towards a gene expression biomarker set for human biological age. Aging Cell, 12(2), 324-326. Abstract.  Full text.
Dutta A, Henley W, Pilling LC, Wallace RB, Melzer D (2013). Uric acid measurement improves prediction of cardiovascular mortality in later life. J Am Geriatr Soc, 61(3), 319-326. Abstract.  Author URL.

2012

Metcalf B, Henley W, Wilkin T (2012). Authors' reply to Symonds. BMJ, 345
Harries LW, Pilling LC, Hernandez LDG, Bradley-Smith R, Henley W, Singleton AB, Guralnik JM, Bandinelli S, Ferrucci L, Melzer D, et al (2012). CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength. Aging Cell, 11(2), 262-268. Abstract.  Author URL.  Full text.
Hartley C, Donaldson D, Smith KC, Henley W, Lewis TW, Blott S, Mellersh C, Barnett KC (2012). Congenital keratoconjunctivitis sicca and ichthyosiform dermatosis in 25 Cavalier King Charles spaniel dogs. Part I: clinical signs, histopathology, and inheritance. Vet Ophthalmol, 15(5), 315-326. Abstract.  Author URL.
Melzer D, Gates P, Osborn NJ, Henley WE, Cipelli R, Young A, Money C, McCormack P, Schofield P, Mosedale D, et al (2012). Correction: Urinary Bisphenol a Concentration and Angiography-Defined Coronary Artery Stenosis. PLoS One, 7(11). Abstract.  Author URL.
Metcalf B, Henley W, Wilkin T (2012). Effectiveness of intervention on physical activity of children: Systematic review and meta-analysis of controlled trials with objectively measured outcomes (EarlyBird 54). BMJ (Online), 345(7876). Abstract.  Full text.
Norman SM (2012). Factors influencing the outcomes of children utilising CAMHS.  Full text.
Hunter J, Madden R, Stone A, Osborne N, Wheeler B, Barlow M, Bendall R, Lin N, Henley W, Gaze W, et al (2012). HEPATITIS E (HEV) IN SOUTH WEST ENGLAND. GEOGRAPHICAL, ENVIRONMENTAL AND SOCIAL FACTORS: a CASE CONTROL STUDY.  Author URL.
Madden RG, Harrison A, Scobie L, Crossan C, Hunter JG, Parry R, Johnston P, Stratton J, Dickinson S, Bendall R, et al (2012). HEV IN RENAL TRANSPLANT AND HAEMODIALYSIS PATIENTS.  Author URL.
Keane FE, Gompels M, Bendall RP, Drayton R, Jennings L, Black J, Baragwanath G, Lin NX, Henley WE, Ngui S-L, et al (2012). Hepatitis E virus coinfection in patients with HIV infection. HIV MEDICINE, 13(1), 83-88. Author URL.
Metcalf B, Henley W, Wilkin T (2012). Keeping the customer satisfied reply. BRITISH MEDICAL JOURNAL, 345 Author URL.
Madden RG, Hunter JG, Stone AM, Thornton C, Barlow M, Lewis J, Bendall R, Lin N, Henley W, Dalton HR, et al (2012). LOCALLY ACQUIRED HEPATITIS E. GEOGRAPHICAL CLUSTERING AND ENVIRONMENTAL FACTORS: a NESTED CASE CONTROL STUDY.  Author URL.
Harries LW, Bradley-Smith RM, Llewellyn DJ, Pilling LC, Fellows A, Henley W, Hernandez D, Guralnik JM, Bandinelli S, Singleton A, et al (2012). Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults. Rejuvenation Res, 15(4), 395-404. Abstract.  Author URL.  Full text.
Melzer D, Dutta A, Henley W, Langa K, Wallace RB, Robine J (2012). MIDDLE-AGED OFFSPRING OF LONG LIVED PARENTS IN HRS. GERONTOLOGIST, 52, 414-414. Author URL.
Wyatt K, Henley W, Anderson L, Anderson R, Nikolaou V, Stein K, Klinger L, Hughes D, Waldek S, Lachmann R, et al (2012). The effectiveness and cost-effectiveness of enzyme and substrate replacement therapies: a longitudinal cohort study of people with lysosomal storage disorders. HEALTH TECHNOLOGY ASSESSMENT, 16(39), V-+. Author URL.
Melzer D, Osborne NJ, Henley WE, Cipelli R, Young A, Money C, McCormack P, Luben R, Khaw K-T, Wareham NJ, et al (2012). Urinary bisphenol a concentration and risk of future coronary artery disease in apparently healthy men and women. Circulation, 125(12), 1482-1490. Abstract.  Author URL.  Full text.
Melzer D, Gates P, Osborne NJ, Henley WE, Cipelli R, Young A, Money C, McCormack P, Schofield P, Mosedale D, et al (2012). Urinary bisphenol a concentration and angiography-defined coronary artery stenosis. PLoS One, 7(8). Abstract.  Author URL.  Full text.

2011

Goodwin VA, Richards SH, Henley W, Ewings P, Taylor AH, Campbell JL (2011). An exercise intervention to prevent falls in people with Parkinson's disease: a pragmatic randomised controlled trial. Journal of Neurology, Neurosurgery and Psychiatry, 82(11), 1232-1238. Abstract.  Full text.
Melzer D, Harries L, Cipelli R, Henley W, Money C, McCormack P, Young A, Guralnik J, Ferrucci L, Bandinelli S, et al (2011). Bisphenol a exposure is associated with in vivo estrogenic gene expression in adults. Environ Health Perspect, 119(12), 1788-1793. Abstract.  Author URL.  Full text.
Rice NE, Lang IA, Henley W, Melzer D (2011). Common health predictors of early retirement: findings from the English Longitudinal Study of Ageing. Age Ageing, 40(1), 54-61. Abstract.  Author URL.
Metcalf BS, Hosking J, Jeffery AN, Voss LD, Henley W, Wilkin TJ (2011). Fatness leads to inactivity, but inactivity does not lead to fatness: a longitudinal study in children (EarlyBird 45). Arch Dis Child, 96(10), 942-947. Abstract.  Author URL.
Dalton HR, Bendall RP, Rashid M, Ellis V, Ali R, Ramnarace R, Stableforth W, Headdon W, Abbott R, McLaughlin C, et al (2011). Host risk factors and autochthonous hepatitis E infection. Eur J Gastroenterol Hepatol, 23(12), 1200-1205. Abstract.  Author URL.
Harries LW, Hernandez D, Henley W, Wood AR, Holly AC, Bradley-Smith RM, Yaghootkar H, Dutta A, Murray A, Frayling TM, et al (2011). Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing. Aging Cell, 10(5), 868-878. Abstract.  Author URL.
Hoyle MW, Henley W (2011). Improved curve fits to summary survival data: application to economic evaluation of health technologies. BMC Med Res Methodol, 11 Abstract.  Author URL.  Full text.
Dutta A, Henley W, Lang I, Llewellyn D, Guralnik J, Wallace RB, Melzer D (2011). Predictors of extraordinary survival in the Iowa established populations for epidemiologic study of the elderly: cohort follow-up to "extinction". J Am Geriatr Soc, 59(6), 963-971. Abstract.  Author URL.
MacKichan F, Paterson C, Henley WE, Britten N (2011). Self-care in people with long term health problems: a community based survey. BMC Fam Pract, 12 Abstract.  Author URL.  Full text.
Dutta A, Henley W, Lang IA, Murray A, Guralnik J, Wallace RB, Melzer D (2011). The coronary artery disease-associated 9p21 variant and later life 20-year survival to cohort extinction. Circ Cardiovasc Genet, 4(5), 542-548. Abstract.  Author URL.

2010

Melzer D, Rice N, Depledge MH, Henley WE, Galloway TS (2010). Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the U.S. National Health and Nutrition Examination Survey. Environ Health Perspect, 118(5), 686-692. Abstract.  Author URL.  Full text.
Melzer D, Rice NE, Lewis C, Henley WE, Galloway TS (2010). Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06. PLoS One, 5(1). Abstract.  Author URL.  Full text.
Rice NE, Lang IA, Henley W, Melzer D (2010). Baby boomers nearing retirement: the healthiest generation?. Rejuvenation Res, 13(1), 105-114. Abstract.  Author URL.
Hosking J, Henley W, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ (2010). Changes in resting energy expenditure and their relationship to insulin resistance and weight gain: a longitudinal study in pre-pubertal children (EarlyBird 17). Clin Nutr, 29(4), 448-452. Abstract.  Author URL.
Dalton HR, Bendall RP, Pritchard C, Henley W, Melzer D (2010). National mortality rates from chronic liver disease and consumption of alcohol and pig meat. Epidemiol Infect, 138(2), 174-182. Abstract.  Author URL.
Cluett C, Brayne C, Clarke R, Evans G, Matthews F, Rubinsztein DC, Huppert F, Llewellyn DJ, Rice N, Henley W, et al (2010). Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people. Neurobiol Aging, 31(9), 1563-1568. Abstract.  Author URL.

2009

Murray RC, Deaton CM, Smith NC, Henley WE, Marlin DJ (2009). Neither age nor osteoarthritis is associated with synovial fluid antioxidant disturbance or depletion in the horse. Comparative Exercise Physiology, 6(3), 121-128. Abstract.
Parahyba MI, Stevens K, Henley W, Lang IA, Melzer D (2009). Reductions in disability prevalence among the highest income groups of older Brazilians. Am J Public Health, 99(1), 81-86. Abstract.  Author URL.
Cluett C, McDermott MM, Guralnik J, Ferrucci L, Bandinelli S, Miljkovic I, Zmuda JM, Li R, Tranah G, Harris T, et al (2009). The 9p21 myocardial infarction risk allele increases risk of peripheral artery disease in older people. Circ Cardiovasc Genet, 2(4), 347-353. Abstract.  Author URL.

2008

Melzer D, Perry JRB, Hernandez D, Corsi A-M, Stevens K, Rafferty I, Lauretani F, Murray A, Gibbs JR, Paolisso G, et al (2008). A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet, 4(5). Abstract.  Author URL.  Full text.
Lang IA, Galloway TS, Scarlett A, Henley WE, Depledge M, Wallace RB, Melzer D (2008). Association of urinary bisphenol a concentration with medical disorders and laboratory abnormalities in adults. JAMA, 300(11), 1303-1310. Abstract.  Author URL.
Ellis J, Logan S, Pumphrey R, Tan HK, Henley W, Edwards V, Moy R, Gilbert R (2008). Inequalities in provision of the Disability Living Allowance for Down syndrome. Arch Dis Child, 93(1), 14-16. Abstract.  Author URL.
Edwards DS, Coyne K, Dawson S, Gaskell RM, Henley WE, Rogers K, Wood JLN (2008). Risk factors for time to diagnosis of feline upper respiratory tract disease in UK animal adoption shelters. Prev Vet Med, 87(3-4), 327-339. Abstract.  Author URL.
Ellis JM, Tan HK, Gilbert RE, Muller DPR, Henley W, Moy R, Pumphrey R, Ani C, Davies S, Edwards V, et al (2008). Supplementation with antioxidants and folinic acid for children with Down's syndrome: randomised controlled trial. BMJ, 336(7644), 594-597. Abstract.  Author URL.  Full text.
Blissitt KJ, Raisis AL, Adams VJ, Rogers KH, Henley WE, Young LE (2008). The effects of halothane and isoflurane on cardiovascular function in dorsally recumbent horses undergoing surgery. VETERINARY ANAESTHESIA AND ANALGESIA, 35(3), 208-219. Author URL.

2007

Rafiq S, Frayling TM, Murray A, Hurst A, Stevens K, Weedon MN, Henley W, Ferrucci L, Bandinelli S, Corsi A-M, et al (2007). A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects. Genes Immun, 8(7), 552-559. Abstract.  Author URL.
Frayling TM, Rafiq S, Murray A, Hurst AJ, Weedon MN, Henley W, Bandinelli S, Corsi A-M, Ferrucci L, Guralnik JM, et al (2007). An interleukin-18 polymorphism is associated with reduced serum concentrations and better physical functioning in older people. J Gerontol a Biol Sci Med Sci, 62(1), 73-78. Abstract.  Author URL.
Rafiq S, Stevens K, Hurst AJ, Murray A, Henley W, Weedon MN, Bandinelli S, Corsi AM, Guralnik JM, Ferruci L, et al (2007). Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels. Genes Immun, 8(4), 344-351. Abstract.  Author URL.
Johnson MS, Martin MWS, Henley W (2007). Results of pacemaker implantation in 104 dogs. JOURNAL OF SMALL ANIMAL PRACTICE, 48(1), 4-11. Author URL.

2006

Henley WE, Rogers K, Harkins L, Wood JLN (2006). A comparison of survival models for assessing risk of racehorse fatality. Prev Vet Med, 74(1), 3-20. Abstract.  Author URL.
Sparkes AH, Rogers K, Henley WE, Gunn-Moore DA, May JM, Gruffydd-Jones TJ, Bessant C (2006). A questionnaire-based study of gestation, parturition and neonatal mortality in pedigree breeding cats in the UK. J Feline Med Surg, 8(3), 145-157. Abstract.  Author URL.
Scase TJ, Edwards D, Miller J, Henley W, Smith K, Blunden A, Murphy S (2006). Canine mast cell tumors: correlation of apoptosis and proliferation markers with prognosis. J Vet Intern Med, 20(1), 151-158. Abstract.  Author URL.
Platt S, Freeman J, di Stefani A, Wieczorek L, Henley W (2006). Prevalence of unilateral and bilateral deafness in border collies and association with phenotype. J Vet Intern Med, 20(6), 1355-1362. Abstract.  Author URL.
Deaton CM, Brown-Feltner H, Henley WE, Roberts CA, Lekeux P, Schroter RC, Marlin DJ (2006). The effect of inspired gas density on pulmonary artery transmural pressure and exercise induced pulmonary haemorrhage. Equine veterinary journal. Supplement(36), 490-494. Abstract.

2005

Raisis AL, Blissitt KJ, Henley W, Rogers K, Adams V, Young LE (2005). The effects of halothane and isoflurane on cardiovascular function in laterally recumbent horses. Br J Anaesth, 95(3), 317-325. Abstract.  Author URL.
Crouch CF, Daly J, Henley W, Hannant D, Wilkins J, Francis MJ (2005). The use of a systemic prime/mucosal boost strategy with an equine influenza ISCOM vaccine to induce protective immunity in horses. Veterinary Immunology and Immunopathology, 108(3-4), 345-355. Abstract.
Verheyen KLP, Henley WE, Price JS, Wood JLN (2005). Training-related factors associated with dorsometacarpal disease in young Thoroughbred racehorses in the UK. Equine Vet J, 37(5), 442-448. Abstract.  Author URL.

2004

Wood JLN, Lakhani KH, Henley WE (2004). An epidemiological approach to prevention and control of three common heritable diseases in canine pedigree breeds in the United Kingdom. Vet J, 168(1), 14-27. Abstract.  Author URL.
Daly JM, Yates PJ, Newton JR, Park A, Henley W, Wood JLN, Davis-Poynter N, Mumford JA (2004). Evidence supporting the inclusion of strains from each of the two co-circulating lineages of H3N8 equine influenza virus in vaccines. Vaccine, 22(29-30), 4101-4109. Abstract.  Author URL.
Johnson MS, Martin M, Edwards D, French A, Henley W (2004). Pulmonic stenosis in dogs: Balloon dilation improves clinical outcome. Journal of Veterinary Internal Medicine, 18(5), 656-662. Abstract.
Park AW, Wood JLN, Daly JM, Newton JR, Glass K, Henley W, Mumford JA, Grenfell BT (2004). The effects of strain heterology on the epidemiology of equine influenza in a vaccinated population. Proc Biol Sci, 271(1548), 1547-1555. Abstract.  Author URL.
Edwards DS, Henley WE, Ely ER, Wood JLN (2004). Vaccination and ill-health in dogs: a lack of temporal association and evidence of equivalence. Vaccine, 22(25-26), 3270-3273. Abstract.  Author URL.

2003

Edwards DS, Henley WE, Harding EF, Dobson JM, Wood JLN (2003). Breed incidence of lymphoma in a UK population of insured dogs. Vet Comp Oncol, 1(4), 200-206. Abstract.  Author URL.
Henley WE, Wood JLN (2003). One hundred and one Dalmatians - the importance of being 'Patch'?. Veterinary Journal, 166(2), 105-106.

2002

Ghani AC, Henley WE, Donnelly CA, Mayer S, Anderson RM (2002). Response to comments on the comparison of the effectiveness of non-nucleoside reverse transcriptase inhibitor and protease inhibitor-containing regimens using observational databases [6]. AIDS, 16(2), 302-303.

2001

Ghani AC, Henley WE, Donnelly CA, Mayer S, Anderson RM (2001). Comparison of the effectiveness of non-nucleoside reverse transcriptase inhibitor-containing and protease inhibitor-containing regimens using observational databases. AIDS, 15(9), 1133-1142. Abstract.

1997

Hand DJ, Henley WE (1997). Statistical classification methods in consumer credit scoring: a review. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 160, 523-541. Author URL.

1996

Henley WE, Hand DJ (1996). A k-nearest-neighbour classifier for assessing consumer credit risk. Journal of the Royal Statistical Society Series D: the Statistician, 45(1), 77-95. Abstract.

1993

Hand DJ, Henley WE (1993). Can reject inference ever work?. IMA Journal of Management Mathematics, 5(1), 45-55. Abstract.

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