Publications by year
In Press
Brand S, Owens C (In Press). Engaging people with common mental health problems who are experiencing the criminal justice system: What are the key elements of good practice and how do they ‘work’?. Health and Justice Journal
Benson O, Gibson S, Brand SL (In Press). The impact of participating in online qualitative suicide research. Journal of Suicide and Life Threatening Behaviours
Brand SL, Gibson S, Burt S, Boden Z, Benson O (In Press). Understanding treatment non-adherence in schizophrenia and bipolar disorder: a survey of what service users do and why. BMC Psychiatry, 13
2019
Brand SL, Quinn C, Pearson M, Lennox C, Owens C, Kirkpatrick T, Callaghan L, Stirzaker A, Michie S, Maguire M, et al (2019). Building programme theory to develop more adaptable and scalable complex interventions: Realist formative process evaluation prior to full trial.
Evaluation,
25(2), 149-170.
Abstract:
Building programme theory to develop more adaptable and scalable complex interventions: Realist formative process evaluation prior to full trial
Medical Research Council guidelines recognise the need to optimise complex interventions prior to full trial through greater understanding of underlying theory and formative process evaluation, yet there are few examples. A realist approach to formative process evaluation makes a unique contribution through a focus on theory formalisation and abstraction. The success of an intervention is dependent on the extent to which it gels or jars with existing provision and can be successfully transferred to new contexts. Interventions with underlying programme theory about how they work, for whom, and under which circumstances will be better able to adapt to work with (rather than against) different services, individuals, and settings. In this methodological article, we describe and illustrate how a realist approach to formative process evaluation develops contextualised intervention theory that can underpin more adaptable and scalable interventions. We discuss challenges and benefits of this approach.
Abstract.
Brand SL, Morgan F, Stabler L, Weightman AL, Willis S, Searchfield L, Nurmatov U, Kemp AM, Turley R, Scourfield J, et al (2019). Mapping the evidence about what works to safely reduce the entry of children and young people into statutory care: a systematic scoping review protocol.
BMJ Open,
9(8), e026967-e026967.
Abstract:
Mapping the evidence about what works to safely reduce the entry of children and young people into statutory care: a systematic scoping review protocol
IntroductionThe increasing number of children and young people entering statutory care in the UK is a significant social, health and educational priority. Development of effective approaches to safely reduce this number remains a complex but critical issue. Despite a proliferation in interventions, evidence summaries are limited. The present protocol outlines a scoping review of research evidence to identify what works in safely reducing the number of children and young people (aged ≤18 years) entering statutory social care. The mapping of evidence gaps, clusters and uncertainties will inform the research programme of the newly funded Department for Education’s What Works Centre for Children’s Social Care.Methods and analysisThe review uses Arksey and O’Malley’s scoping review methodology. Electronic database and website searches will identify studies targeting reduction of care entry, reduction of care re-entry and increase in post-care reunification. Supplementary searching techniques will include international expert consultation. Abstracts and full-text studies will be independently screened by two reviewers. Ten per cent of data abstraction will be independently conducted by two reviewers, with the remainder being extracted and then verified by a second reviewer. Descriptive numerical summaries and a thematic qualitative synthesis will be generated. Evidence will be synthesised according to primary outcome, intervention point (mapped across socioecological domains) and the realist EMMIE categorisation of evidence type (Effectiveness; Mechanisms of change; Moderators; Implementation; Economic evaluation).Ethics and disseminationOutputs will be a conceptual evidence map, a descriptive table quantitatively summarising evidence and a qualitative narrative summary. Results will be disseminated through a peer-reviewed publication, conference presentations, the What Works Centre website, and knowledge translation events with policy-makers and practitioners. Findings will inform the primary research programme of the What Works Centre for Children’s Social Care and the subsequent suite of systematic reviews to be conducted by the Centre in this substantive area.
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2018
Kirkpatrick T, Lennox C, Taylor R, Anderson R, Maguire M, Haddad M, Michie S, Owens C, Durcan G, Stirzaker A, et al (2018). Evaluation of a complex intervention (Engager) for prisoners with common mental health problems, near to and after release: study protocol for a randomised controlled trial.
BMJ Open,
8(2).
Abstract:
Evaluation of a complex intervention (Engager) for prisoners with common mental health problems, near to and after release: study protocol for a randomised controlled trial.
INTRODUCTION: the 'Engager' programme is a 'through-the-gate' intervention designed to support prisoners with common mental health problems as they transition from prison back into the community. The trial will evaluate the clinical and cost-effectiveness of the Engager intervention. METHODS AND ANALYSIS: the study is a parallel two-group randomised controlled trial with 1:1 individual allocation to either: (a) the Engager intervention plus standard care (intervention group) or (b) standard care alone (control group) across two investigation centres (South West and North West of England). Two hundred and eighty prisoners meeting eligibility criteria will take part. Engager is a person-centred complex intervention delivered by practitioners and aimed at addressing offenders' mental health and social care needs. It comprises one-to-one support for participants prior to release from prison and for up to 20 weeks postrelease. The primary outcome is change in psychological distress measured by the Clinical Outcomes in Routine Evaluation-Outcome Measure at 6 months postrelease. Secondary outcomes include: assessment of subjective met/unmet need, drug and alcohol use, health-related quality of life and well-being-related quality of life measured at 3, 6 and 12 months postrelease; change in objective social domains, drug and alcohol dependence, service utilisation and perceived helpfulness of services and change in psychological constructs related to desistence at 6 and 12 months postrelease; and recidivism at 12 months postrelease. A process evaluation will assess fidelity of intervention delivery, test hypothesised mechanisms of action and look for unintended consequences. An economic evaluation will estimate the cost-effectiveness. ETHICS AND DISSEMINATION: This study has been approved by the Wales Research Ethics Committee 3 (ref: 15/WA/0314) and the National Offender Management Service (ref: 2015-283). Findings will be disseminated to commissioners, clinicians and service users via papers and presentations. TRIAL REGISTRATION NUMBER: ISRCTN11707331; Pre-results.
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Sheaff R, Brand SL, Lloyd H, Wanner A, Fornasiero M, Briscoe S, Valderas JM, Byng R, Pearson M (2018). From programme theory to logic models for multispecialty community providers: a realist evidence synthesis.
Health Services and Delivery Research,
6(24), 1-210.
Abstract:
From programme theory to logic models for multispecialty community providers: a realist evidence synthesis
. Background
. The NHS policy of constructing multispecialty community providers (MCPs) rests on a complex set of assumptions about how health systems can replace hospital use with enhanced primary care for people with complex, chronic or multiple health problems, while contributing savings to health-care budgets.
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. Objectives
. To use policy-makers’ assumptions to elicit an initial programme theory (IPT) of how MCPs can achieve their outcomes and to compare this with published secondary evidence and revise the programme theory accordingly.
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. Design
. Realist synthesis with a three-stage method: (1) for policy documents, elicit the IPT underlying the MCP policy, (2) review and synthesise secondary evidence relevant to those assumptions and (3) compare the programme theory with the secondary evidence and, when necessary, reformulate the programme theory in a more evidence-based way.
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. Data sources
. Systematic searches and data extraction using (1) the Health Management Information Consortium (HMIC) database for policy statements and (2) topically appropriate databases, including MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, PsycINFO, the Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Applied Social Sciences Index and Abstracts (ASSIA). A total of 1319 titles and abstracts were reviewed in two rounds and 116 were selected for full-text data extraction. We extracted data using a formal data extraction tool and synthesised them using a framework reflecting the main policy assumptions.
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. Results
. The IPT of MCPs contained 28 interconnected context–mechanism–outcome relationships. Few policy statements specified what contexts the policy mechanisms required. We found strong evidence supporting the IPT assumptions concerning organisational culture, interorganisational network management, multidisciplinary teams (MDTs), the uses and effects of health information technology (HIT) in MCP-like settings, planned referral networks, care planning for individual patients and the diversion of patients from inpatient to primary care. The evidence was weaker, or mixed (supporting some of the constituent assumptions but not others), concerning voluntary sector involvement, the effects of preventative care on hospital admissions and patient experience, planned referral networks and demand management systems. The evidence about the effects of referral reductions on costs was equivocal. We found no studies confirming that the development of preventative care would reduce demands on inpatient services. The IPT had overlooked certain mechanisms relevant to MCPs, mostly concerning MDTs and the uses of HITs.
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. Limitations
. The studies reviewed were limited to Organisation for Economic Co-operation and Development countries and, because of the large amount of published material, the period 2014–16, assuming that later studies, especially systematic reviews, already include important earlier findings. No empirical studies of MCPs yet existed.
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. Conclusions
. Multidisciplinary teams are a central mechanism by which MCPs (and equivalent networks and organisations) work, provided that the teams include the relevant professions (hence, organisations) and, for care planning, individual patients. Further primary research would be required to test elements of the revised logic model, in particular about (1) how MDTs and enhanced general practice compare and interact, or can be combined, in managing referral networks and (2) under what circumstances diverting patients from in-patient to primary care reduces NHS costs and improves the quality of patient experience.
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. Study registration
. This study is registered as PROSPERO CRD42016038900.
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. Funding
. The National Institute for Health Research (NIHR) Health Services and Delivery Research programme and supported by the NIHR Collaboration for Leadership in Applied Health Research and Care South West Peninsula.
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Lennox C, Kirkpatrick T, Taylor RS, Todd R, Greenwood C, Haddad M, Stevenson C, Stewart A, Shenton D, Carroll L, et al (2018). Pilot randomised controlled trial of the ENGAGER collaborative care intervention for prisoners with common mental health problems, near to and after release.
Pilot Feasibility Stud,
4Abstract:
Pilot randomised controlled trial of the ENGAGER collaborative care intervention for prisoners with common mental health problems, near to and after release.
BACKGROUND: Rates of common mental health problems are much higher in prison populations, but access to primary care mental health support falls short of community equivalence. Discontinuity of care on release is the norm and is further complicated by substance use and a range of social problems, e.g. homelessness. To address these problems, we worked with criminal justice, third sector social inclusion services, health services and people with lived experiences (peer researchers), to develop a complex collaborative care intervention aimed at supporting men with common mental health problems near to and following release from prison. This paper describes an external pilot trial to test the feasibility of a full randomised controlled trial. METHODS: Eligible individuals with 4 to 16 weeks left to serve were screened to assess for common mental health problems. Participants were then randomised at a ratio of 2:1 allocation to ENGAGER plus standard care (intervention) or standard care alone (treatment as usual). Participants were followed up at 1 and 3 months' post release. Success criteria for this pilot trial were to meet the recruitment target sample size of 60 participants, to follow up at least 50% of participants at 3 months' post release from prison, and to deliver the ENGAGER intervention. Estimates of recruitment and retention rates and 95% confidence intervals (CIs) are reported. Descriptive analyses included summaries (percentages or means) for participant demographics, and baseline characteristics are reported. RESULTS: Recruitment target was met with 60 participants randomised in 9 months. The average retention rates were 73% at 1 month [95% CI 61 to 83] and 47% at 3 months follow-up [95% CI 35 to 59]. Ninety percent of participants allocated to the intervention successfully engaged with a practitioner before release and 70% engaged following release. CONCLUSIONS: This pilot confirms the feasibility of conducting a randomised trial for prison leavers with common mental health problems. Based on this pilot study and some minor changes to the trial design and intervention, a full two-centre randomised trial assessing the clinical and cost-effectiveness of the ENGAGER intervention is currently underway.
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2017
Brand SL, Thompson Coon J, Fleming LE, Carroll L, Bethel A, Wyatt K (2017). Whole-system approaches to improving the health and wellbeing of healthcare workers: a systematic review.
PLoS One,
12(12).
Abstract:
Whole-system approaches to improving the health and wellbeing of healthcare workers: a systematic review.
BACKGROUND: Healthcare professionals throughout the developed world report higher levels of sickness absence, dissatisfaction, distress, and "burnout" at work than staff in other sectors. There is a growing call for the 'triple aim' of healthcare delivery (improving patient experience and outcomes and reducing costs; to include a fourth aim: improving healthcare staff experience of healthcare delivery. A systematic review commissioned by the United Kingdom's (UK) Department of Health reviewed a large number of international healthy workplace interventions and recommended five whole-system changes to improve healthcare staff health and wellbeing: identification and response to local need, engagement of staff at all levels, and the involvement, visible leadership from, and up-skilling of, management and board-level staff. OBJECTIVES: This systematic review aims to identify whole-system healthy workplace interventions in healthcare settings that incorporate (combinations of) these recommendations and determine whether they improve staff health and wellbeing. METHODS: a comprehensive and systematic search of medical, education, exercise science, and social science databases was undertaken. Studies were included if they reported the results of interventions that included all healthcare staff within a healthcare setting (e.g. whole hospital; whole unit, e.g. ward) in collective activities to improve physical or mental health or promote healthy behaviours. RESULTS: Eleven studies were identified which incorporated at least one of the whole-system recommendations. Interventions that incorporated recommendations to address local need and engage the whole workforce fell in to four broad types: 1) pre-determined (one-size-fits-all) and no choice of activities (two studies); or 2) pre-determined and some choice of activities (one study); 3) a wide choice of a range of activities and some adaptation to local needs (five studies); or, 3) a participatory approach to creating programmes responsive and adaptive to local staff needs that have extensive choice of activities to participate in (three studies). Only five of the interventions included substantial involvement and engagement of leadership and efforts aimed at up-skilling the leadership of staff to support staff health and wellbeing. Incorporation of more of the recommendations did not appear to be related to effectiveness. The heterogeneity of study designs, populations and outcomes excluded a meta-analysis. All studies were deemed by their authors to be at least partly effective. Two studies reported statistically significant improvement in objectively measured physical health (BMI) and eight in subjective mental health. Six studies reported statistically significant positive changes in subjectively assessed health behaviours. CONCLUSIONS: This systematic review identified 11 studies which incorporate at least one of the Boorman recommendations and provides evidence that whole-system healthy workplace interventions can improve health and wellbeing and promote healthier behaviours in healthcare staff.
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2015
brand S, Wyatt K, Fleming LE (2015). Tailoring Healthy Workplace Interventions to Local
Healthcare Settings: a Complexity Theory-Informed Workplace
of Well-Being Framework.
e Scientific World Journal(2015).
Abstract:
Tailoring Healthy Workplace Interventions to Local
Healthcare Settings: a Complexity Theory-Informed Workplace
of Well-Being Framework
Many healthy workplace interventions have been developed for healthcare settings to address the consistently low scores of
healthcare professionals on assessments of mental and physical well-being. Complex healthcare settings present challenges for the
scale-up and spread of successful interventions from one setting to another. Despite general agreement regarding the importance
of the local setting in affecting intervention success across different settings, there is no consensus on what it is about a local setting
that needs to be taken into account to design healthy workplace interventions appropriate for different local settings. Complexity
theory principles were used to understand a workplace as a complex adaptive system and to create a framework of eight domains
(system characteristics) that affect the emergence of system-level behaviour. This Workplace of Well-being (WoW) framework is
responsive and adaptive to local settings and allows a shared understanding of the enablers and barriers to behaviour change by
capturing local information for each of the eight domains. We use the results of applying the WoW framework to one workplace,
a UK National Health Service ward, to describe the utility of this approach in informing design of setting-appropriate healthy
workplace interventions that create workplaces conducive to healthy behaviour change.
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Wyatt KM, Brand S, Ashby-Pepper J, Abraham J, Fleming LE (2015). UNDERSTANDING HOW HEALTHY WORKPLACES ARE CREATED: IMPLICATIONS FOR DEVELOPING a NATIONAL HEALTH SERVICE HEALTHY WORKPLACE PROGRAM.
INTERNATIONAL JOURNAL OF HEALTH SERVICES,
45(1), 161-185.
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Pearson M, Brand SL, Quinn C, Shaw J, Maguire M, Michie S, Briscoe S, Lennox C, Stirzaker A, Kirkpatrick T, et al (2015). Using realist review to inform intervention development: Methodological illustration and conceptual platform for collaborative care in offender mental health.
Implementation Science,
10(1).
Abstract:
Using realist review to inform intervention development: Methodological illustration and conceptual platform for collaborative care in offender mental health
Background: This paper reports how we used a realist review, as part of a wider project to improve collaborative mental health care for prisoners with common mental health problems, to develop a conceptual platform. The importance of offenders gaining support for their mental health, and the need for practitioners across the health service, the criminal justice system, and the third sector to work together to achieve this is recognised internationally. However, the literature does not provide coherent analyses of how these ambitions can be achieved. This paper demonstrates how a realist review can be applied to inform complex intervention development that spans different locations, organisations, professions, and care sectors. Methods: We applied and developed a realist review for the purposes of intervention development, using a three-stage process. (1) an iterative database search strategy (extending beyond criminal justice and offender health) and groups of academics, practitioners, and people with lived experience were used to identify explanatory accounts (n = 347). (2) from these accounts, we developed consolidated explanatory accounts (n = 75). (3) the identified interactions between practitioners and offenders (within their organisational, social, and cultural contexts) were specified in a conceptual platform. We also specify, step by step, how these explanatory accounts were documented, consolidated, and built into a conceptual platform. This addresses an important methodological gap for social scientists and intervention developers about how to develop and articulate programme and implementation theory underpinning complex interventions. Results: an integrated person-centred system is proposed to improve collaborative mental health care for offenders with common mental health problems (near to and after release) by achieving consistency between the goals of different sectors and practitioners, enabling practitioners to apply scientific and experiential knowledge in working judiciously and reflectively, and building systems and aligning resources that are centred on offenders' health and social care needs. Conclusions: As part of a broader programme of work, a realist review can make an important contribution to the specification of theoretically informed interventions that have the potential to improve health outcomes. Our conceptual platform has potential application in related systems of health and social care where integrated, and person-centred care is a goal.
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Pearson M, Brand SL, Quinn C, Shaw J, Maguire M, Michie S, Briscoe S, Lennox C, Stirzaker A, Kirkpatrick T, et al (2015). Using realist review to inform intervention development: methodological illustration and conceptual platform for collaborative care in offender mental health.
IMPLEMENTATION SCIENCE,
10 Author URL.
2014
Gibson S, Boden ZVR, Benson O, Brand SL (2014). The Impact of Participating in Suicide Research Online.
SUICIDE AND LIFE-THREATENING BEHAVIOR,
44(4), 372-383.
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2013
Gibson S, Benson O, Brand SL (2013). Talking about suicide: Confidentiality and anonymity in qualitative research.
NURSING ETHICS,
20(1), 18-29.
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Benson O, Gibson S, Brand SL (2013). The Experience of Agency in the Feeling of Being Suicidal.
JOURNAL OF CONSCIOUSNESS STUDIES,
20(7-8), 56-79.
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Benson O, Gibson S, Brand SL (2013). The experience of agency in the feeling of being suicidal. Journal of Consciousness Studies: controversies in science and the humanities, 20(24), 56-79.