COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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Dr Sam Merriel

Dr Sam Merriel

Clinical Senior Research Fellow

 College House 1.18

 

College House, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK

Overview

Dr Sam Merriel is a GP and Clinical Senior Research Fellow funded by the CanTest Collaborative, Cancer Research UK's inaugural Catalyst Award programme. Led by Prof Willie Hamilton (Exeter) and Dr Fiona Walter (Cambridge), the CanTest Collaborative is a team of primary care cancer researchers who are investigating ways of developing and implementing new and improved cancer diagnostic tests into GP surgeries. Dr Merriel is working with the Diagnosis of Symptomatic Cancer Optimally (DISCO) team within the Medical School to study the potential impact of Multiparametric Magnetic Resonance Imaging (mpMRI) as a diagnostic test for prostate cancer within primary care.

Prior to joining the DISCO team, Dr Merriel completed an NIHR Academic Clinical Fellowship in General Practice in Bristol, working within the Centre for Academic Primary Care at the University of Bristol. Dr Merriel obtained Membership of the Royal College of General Practitioners (MRCGP) in August 2018. He has also completed a Masters of Science (Public Health) at the London School of Hygiene & Tropical Medicine.

 

Qualifications

MRCGP - Member of Royal College of General Practitioners, UK (August 2018)

MSc - Masters of Science (Public Health), London School of Hygiene and Tropical Medicine, UK (2012-2013)

MBBS (Hons) - Bachelor of Medicine, Bachelor of Surgery (with honours), Monash University, Australia (2004 - 2009)

BMedSc (Hons) - Bachelor of Medical Science (with honours), Monash University, Australia (2007)

Links

Research group links

Research

Research interests

Dr Merriel’s primary research interests focus around the prevention and early detection of cancer in primary care. He is currently studying the potential impact of Multiparametric Magnetic Resonance Imaging (mpMRI) as a diagnostic test for prostate cancer within primary care. He is exploring the accepatability, cost effectiveness, and patient centred outcomes associated with mpMRI.

He has been co-investigator in studies of Human Papillomavirus (HPV) vaccination in males and early detection of childhood obesity in primary care that were funded by Cancer Research UK/BUPA Foundation Innovation Awards. Dr Merriel also has experience working with routine primary care datasets, such as the Clinical Practice Research Datalink (CPRD). He has conducted studies of associations between hypoalbuminaemia and undiagnosed cancers, and identifying prognostic factors for prostate cancer from primary care electronic health records.

Research projects

Current Projects:

  • Multiparametric magnetic resonance imaging for prostate cancer diagnosis in primary care
  • Screening, Prevention and Early Diagnosis of cancer research: A systematic mapping review
  • Active surveillance in 2019: A modified Delphi study to develop a practical guide for physicians advising patients on active surveillance as a treatment option for prostate cancer
  • What have they learnt? Have knowledge, skills and/or attitudes changed as a result of an Out-Of-Program-Experience (OOPE) in global health during UK general practice training?

Research networks

CanTest Collaborative

Society for Academic Primary Care

Primary care Academic CollaboraTive (PACT)

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Merriel SWD (In Press). Active surveillance for prostate cancer: an update. Trends in Urology and Men’s Health
Merriel SWD (In Press). Comparison of multiparametric magnetic resonance imaging and targeted biopsy with systematic biopsy alone for the diagnosis of prostate cancer. JAMA Network Open
Merriel SWD, Gnanapragasam V (In Press). Prostate cancer treatment choices: the GP’s role in shared decision-making. British Journal of General Practice
Merriel SWD, Tsukagoshi S, Caesar S, Weaver R (In Press). Qualified GPs planning to work overseas: Go, enjoy yourself, and come back’. British Journal of General Practice
Merriel SWD, Hetherington L, Seggie A, Castle JT, Cross W, Roobol MJ, Gnanapragasam V, Moore CM, Prostate Cancer UK Expert Reference Group on Active Surveillance (2019). Best practice in active surveillance for men with prostate cancer: a Prostate Cancer UK consensus statement. BJU Int, 124(1), 47-54. Abstract.  Author URL.
Elwenspoek MMC, Sheppard AL, McInnes MDF, Merriel SWD, Rowe EWJ, Bryant RJ, Donovan JL, Whiting P (2019). Comparison of Multiparametric Magnetic Resonance Imaging and Targeted Biopsy with Systematic Biopsy Alone for the Diagnosis of Prostate Cancer: a Systematic Review and Meta-analysis. JAMA Netw Open, 2(8). Abstract.  Author URL.
Kesten JM, Flannagan C, Ruane-McAteer E, Merriel SWD, Nadarzynski T, Shapiro G, Rosberger Z, Prue G (2019). Mixed-methods study in England and Northern Ireland to understand young men who have sex with men's knowledge and attitudes towards human papillomavirus vaccination. BMJ Open, 9(5). Abstract.  Author URL.
Merriel SWD, Hardy V, Thompson M, Walter FM, Hamilton W (2019). Patient-Centered Outcomes from Multiparametric MRI and MRI-Guided Biopsy for Prostate Cancer: a Systematic Review. J Am Coll Radiol Abstract.  Author URL.
Merriel SW, Nadarzynski T, Kesten JM, Flannagan C, Prue G (2018). 'Jabs for the boys': time to deliver on HPV vaccination recommendations. Br J Gen Pract, 68(674), 406-407. Author URL.
Merriel SWD, Flannagan C, Kesten JM, Shapiro GK, Nadarzynski T, Prue G (2018). Knowledge and Attitudes of General Practitioners and Sexual Health Care Professionals Regarding Human Papillomavirus Vaccination for Young Men Who Have Sex with Men. Int J Environ Res Public Health, 15(1). Abstract.  Author URL.
Nicholson BD, Shinkins B, Price S, Verbakel JY, Merriel S (2018). National cancer control plans. The Lancet Oncology, 19(12).
Merriel SWD, May MT, Martin RM (2018). Predicting prostate cancer progression: protocol for a retrospective cohort study to identify prognostic factors for prostate cancer outcomes using routine primary care data. BMJ Open, 8(1). Abstract.  Author URL.
Merriel SWD, Funston G, Hamilton W (2018). Prostate Cancer in Primary Care. Adv Ther, 35(9), 1285-1294. Abstract.  Author URL.  Full text.
(2017). Abstracts of the 2017 World Congress of Psycho-Oncology, 14-18 August 2017, Berlin, Germany. Psychooncology, 26 Suppl 3, 3-167. Author URL.
Merriel SWD, Turner EL, Walsh E, Young GJ, Metcalfe C, Hounsome L, Tudge I, Donovan J, Hamdy F, Neal D, et al (2017). Cross-sectional study evaluating data quality of the National Cancer Registration and Analysis Service (NCRAS) prostate cancer registry data using the Cluster randomised trial of PSA testing for Prostate cancer (CAP). BMJ Open, 7(11). Abstract.  Author URL.
Lim RS, Evans L, George AP, de Alwis N, Stimpson P, Merriel S, Giddings CEB, Billah B, Smith JA, Safdar A, et al (2017). Do demographics and tumour-related factors affect nodal yield at neck dissection? a retrospective cohort study. J Laryngol Otol, 131(S1), S36-S40. Abstract.  Author URL.
Merriel A, Murove BT, Merriel SWD, Sibanda T, Moyo S, Crofts J (2017). Implementation of a modified obstetric early warning system to improve the quality of obstetric care in Zimbabwe. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 136(2), 175-179. Author URL.
Merriel SWD (2017). Management of angina in primary care. Nurse Prescribing, 15(10), 492-497.
Merriel SWD, Carroll R, Hamilton F, Hamilton W (2016). Association between unexplained hypoalbuminaemia and new cancer diagnoses in UK primary care patients. Fam Pract, 33(5), 449-452. Abstract.  Author URL.
Merriel A, van der Nelson H, Merriel S, Bennett J, Donald F, Draycott T, Siassakos D (2016). Identifying Deteriorating Patients Through Multidisciplinary Team Training. Am J Med Qual, 31(6), 589-595. Abstract.  Author URL.
Merriel S (2015). Critically appraising the evidence. InnovAiT: Education and inspiration for general practice, 8(9), 562-568.
Merriel SWD, Salisbury C, Metcalfe C, Ridd M (2015). Depth of the patient-doctor relationship and content of general practice consultations: cross-sectional study. BRITISH JOURNAL OF GENERAL PRACTICE, 65(637), E545-E551. Author URL.
Merriel SWD, Andrews V, Salisbury C (2014). Telehealth interventions for primary prevention of cardiovascular disease: a systematic review and meta-analysis. PREVENTIVE MEDICINE, 64, 88-95. Author URL.
Merriel SWD, Andrews V, Salisbury C (2014). Telehealth interventions for primary prevention of cardiovascular disease: a systematic review and meta-analysis (vol 64, pg 88, 2014). PREVENTIVE MEDICINE, 67, 343-343. Author URL.

Conferences

Prue GE, Flannagan C, Ruane-McAteer E, Merriel SWD, Nadarzynski T, Shapiro GK, Rosberger Z, Kesten JM (2018). "The only way round it is if every male child is vaccinated"; exploring the views of young men-who-have-sex-with-men towards HPV vaccination: a qualitative study.  Author URL.
Fildes A, Aicken C, Merriel SWD, Llewellyn C (2017). Developing a communication toolbox for primary care practitioners to raise the issue of weight with parents of preschool children: a qualitative study.  Author URL.
Prue G, Flannagan C, Kesten J, Merriel S, Shapiro G, Rosberger Z (2017). Exploring views regarding targeted HPV vaccination in young men who have sex with men and their healthcare professionals.  Author URL.
Merriel SWD, Turner EL, Walsh E, Young G, Metcalfe C, Hounsome L, Tudge I, Donovan J, Hamdy F, Neal D, et al (2016). Validation of the National Cancer Registration and Analysis Service prostate cancer registry with data from the CAP study.  Author URL.

Publications by year


In Press

Merriel SWD (In Press). Active surveillance for prostate cancer: an update. Trends in Urology and Men’s Health
Merriel SWD (In Press). Comparison of multiparametric magnetic resonance imaging and targeted biopsy with systematic biopsy alone for the diagnosis of prostate cancer. JAMA Network Open
Merriel SWD, Gnanapragasam V (In Press). Prostate cancer treatment choices: the GP’s role in shared decision-making. British Journal of General Practice
Merriel SWD, Tsukagoshi S, Caesar S, Weaver R (In Press). Qualified GPs planning to work overseas: Go, enjoy yourself, and come back’. British Journal of General Practice

2019

Merriel SWD, Hetherington L, Seggie A, Castle JT, Cross W, Roobol MJ, Gnanapragasam V, Moore CM, Prostate Cancer UK Expert Reference Group on Active Surveillance (2019). Best practice in active surveillance for men with prostate cancer: a Prostate Cancer UK consensus statement. BJU Int, 124(1), 47-54. Abstract.  Author URL.
Elwenspoek MMC, Sheppard AL, McInnes MDF, Merriel SWD, Rowe EWJ, Bryant RJ, Donovan JL, Whiting P (2019). Comparison of Multiparametric Magnetic Resonance Imaging and Targeted Biopsy with Systematic Biopsy Alone for the Diagnosis of Prostate Cancer: a Systematic Review and Meta-analysis. JAMA Netw Open, 2(8). Abstract.  Author URL.
Kesten JM, Flannagan C, Ruane-McAteer E, Merriel SWD, Nadarzynski T, Shapiro G, Rosberger Z, Prue G (2019). Mixed-methods study in England and Northern Ireland to understand young men who have sex with men's knowledge and attitudes towards human papillomavirus vaccination. BMJ Open, 9(5). Abstract.  Author URL.
Merriel SWD, Hardy V, Thompson M, Walter FM, Hamilton W (2019). Patient-Centered Outcomes from Multiparametric MRI and MRI-Guided Biopsy for Prostate Cancer: a Systematic Review. J Am Coll Radiol Abstract.  Author URL.

2018

Prue GE, Flannagan C, Ruane-McAteer E, Merriel SWD, Nadarzynski T, Shapiro GK, Rosberger Z, Kesten JM (2018). "The only way round it is if every male child is vaccinated"; exploring the views of young men-who-have-sex-with-men towards HPV vaccination: a qualitative study.  Author URL.
Merriel SW, Nadarzynski T, Kesten JM, Flannagan C, Prue G (2018). 'Jabs for the boys': time to deliver on HPV vaccination recommendations. Br J Gen Pract, 68(674), 406-407. Author URL.
Merriel SWD, Flannagan C, Kesten JM, Shapiro GK, Nadarzynski T, Prue G (2018). Knowledge and Attitudes of General Practitioners and Sexual Health Care Professionals Regarding Human Papillomavirus Vaccination for Young Men Who Have Sex with Men. Int J Environ Res Public Health, 15(1). Abstract.  Author URL.
Nicholson BD, Shinkins B, Price S, Verbakel JY, Merriel S (2018). National cancer control plans. The Lancet Oncology, 19(12).
Merriel SWD, May MT, Martin RM (2018). Predicting prostate cancer progression: protocol for a retrospective cohort study to identify prognostic factors for prostate cancer outcomes using routine primary care data. BMJ Open, 8(1). Abstract.  Author URL.
Merriel SWD, Funston G, Hamilton W (2018). Prostate Cancer in Primary Care. Adv Ther, 35(9), 1285-1294. Abstract.  Author URL.  Full text.

2017

(2017). Abstracts of the 2017 World Congress of Psycho-Oncology, 14-18 August 2017, Berlin, Germany. Psychooncology, 26 Suppl 3, 3-167. Author URL.
Merriel SWD, Turner EL, Walsh E, Young GJ, Metcalfe C, Hounsome L, Tudge I, Donovan J, Hamdy F, Neal D, et al (2017). Cross-sectional study evaluating data quality of the National Cancer Registration and Analysis Service (NCRAS) prostate cancer registry data using the Cluster randomised trial of PSA testing for Prostate cancer (CAP). BMJ Open, 7(11). Abstract.  Author URL.
Fildes A, Aicken C, Merriel SWD, Llewellyn C (2017). Developing a communication toolbox for primary care practitioners to raise the issue of weight with parents of preschool children: a qualitative study.  Author URL.
Lim RS, Evans L, George AP, de Alwis N, Stimpson P, Merriel S, Giddings CEB, Billah B, Smith JA, Safdar A, et al (2017). Do demographics and tumour-related factors affect nodal yield at neck dissection? a retrospective cohort study. J Laryngol Otol, 131(S1), S36-S40. Abstract.  Author URL.
Prue G, Flannagan C, Kesten J, Merriel S, Shapiro G, Rosberger Z (2017). Exploring views regarding targeted HPV vaccination in young men who have sex with men and their healthcare professionals.  Author URL.
Merriel A, Murove BT, Merriel SWD, Sibanda T, Moyo S, Crofts J (2017). Implementation of a modified obstetric early warning system to improve the quality of obstetric care in Zimbabwe. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 136(2), 175-179. Author URL.
Merriel SWD (2017). Management of angina in primary care. Nurse Prescribing, 15(10), 492-497.

2016

Merriel SWD, Carroll R, Hamilton F, Hamilton W (2016). Association between unexplained hypoalbuminaemia and new cancer diagnoses in UK primary care patients. Fam Pract, 33(5), 449-452. Abstract.  Author URL.
Merriel A, van der Nelson H, Merriel S, Bennett J, Donald F, Draycott T, Siassakos D (2016). Identifying Deteriorating Patients Through Multidisciplinary Team Training. Am J Med Qual, 31(6), 589-595. Abstract.  Author URL.
Merriel SWD, Turner EL, Walsh E, Young G, Metcalfe C, Hounsome L, Tudge I, Donovan J, Hamdy F, Neal D, et al (2016). Validation of the National Cancer Registration and Analysis Service prostate cancer registry with data from the CAP study.  Author URL.

2015

Merriel S (2015). Critically appraising the evidence. InnovAiT: Education and inspiration for general practice, 8(9), 562-568.
Merriel SWD, Salisbury C, Metcalfe C, Ridd M (2015). Depth of the patient-doctor relationship and content of general practice consultations: cross-sectional study. BRITISH JOURNAL OF GENERAL PRACTICE, 65(637), E545-E551. Author URL.

2014

Merriel SWD, Andrews V, Salisbury C (2014). Telehealth interventions for primary prevention of cardiovascular disease: a systematic review and meta-analysis. PREVENTIVE MEDICINE, 64, 88-95. Author URL.
Merriel SWD, Andrews V, Salisbury C (2014). Telehealth interventions for primary prevention of cardiovascular disease: a systematic review and meta-analysis (vol 64, pg 88, 2014). PREVENTIVE MEDICINE, 67, 343-343. Author URL.

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