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 Rob Andrews

Rob Andrews

Associate Professor of Diabetes/Honorary Consultant in Diabetes

 01392 40 8327

 RILD Building 3.04, Medical Research

 

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Rob  is an associate Professor of Diabetes at the University of Exeter and an Honorary Consultant Physician at Musgrove Park Hospital Taunton. 

At Musgrove park hospital Rob is the Clinical lead for obesity. In this role he has overseen the development of one of the largest multidisciplinary obesity services in the country. This is a holistic service offering specialised dietary and exercise programs, drug therapy and bariatric surgery as well as running clinics for people with eating disorders and complications post surgery. In recognition of this service Taunton has been designated an International Centre of Excellence for Bariatric Surgery, one of only 2 European centres to achieve this status. Rob also runs specialist adult, adolescent and paediatric sports clinics to give advice to sports men, women and children who have Type 1 diabetes.

At the University Rob concentrates on conducting clinical studies to determine the best ways to prevent and manage Type 1 and Type 2 diabetes. He has over 25 years experience of running clinical trials. These trials range from first in man studies to very large RCTs.  Past clinical trials that he has conducted include: the Early ACTID study the world largest diet and exercise study in patients with Newly diagnosed Type 2 diabetes: the STAMP 2 study which examined the role that sedentary time had in the metabolic characteristics of patients with Type 2 diabetes; and the EXTOD study, the first study to examine whether regular exercise can protect beta cell function in patients with newly diagnosed Type 1 diabetes.  He has also been involved in a number of investigator lead CTIMP studies in this area these include the first in man study to look at the effect of blocking 11B-HSD on insulin resistance in patients with Type 2 diabetes and a study to examine the safety and immune effects of immunotherapy with proinsulin peptide in new-onset type 1 diabetes.

Qualifications

  • 1991 MB ChB, University of Birmingham
  • 1995 MRCP UK
  • 2002 CCST Diabetes, Endocrinology and General Internal Medicine
  • 2004 PhD, Unversity of Edinburgh
  • 2014 FRCP UK

Research

Research interests

Currently rob’s research is concentrated in three main areas

  1. Understanding how better to support patients with Type 1 diabetes to exercise – this includes conducting studies to determine the best advice to give as well as development of education material to upskill patients and health care workers.
  2. Trying to develop and validate a brief dietary intervention that can be used in primary care.
  3. Determining the best surgical option for obese patients with different morbidities. 

Research projects

  • EXTOD Education – funded by the NIHR this study aims to develop and pilot an education programme for people with Type 1 diabetes (with accompanying training for health care professionals to deliver this programme) to guide insulin and carbohydrate adjustment for safe exercise.
  • EXTOD follow up  – this study aims to determine the longterm effects of regular exercise on beta cells function in Newly diagnosed patients with Type 1 diabetes.
  • EXTOD 101 – this study aims to determine the effect of regular training on glucose variability and hypoglycaemic rates in patients with Type 1 diabetes.
  • ByBandSleeve – Funded by the HTA this study aims to determine the best surgical treatment for obesity.
  • Does the UKDDQ measure dietary change? – funded by the NIHR this study aims to determine whether a brief dietary tool, that we have developed, can measure change in dietary intake.
  • Type 1 HIT – Funded by DRWF this study aims to determine whether High intensity interval training is an efficient and effective form of exercise for people with Type 1 diabetes.

Research grants

  • 2018 Supporting adult patients with Type 1 Diabetes (T1DM) to undertake exercise; Developing and piloting an education programme on exercise and Type 1 diabetes; EXTOD education (Chief investigator).
    Supporting adult patients with Type 1 Diabetes (T1DM) to undertake exercise; Developing and piloting an education programme on exercise and Type 1 diabetes; EXTOD education (Chief investigator).
  • 2018 BY-BAND: Gastric BYpass or adjustable gastric BANDing surgery to treat morbid obesity: a multi-centre randomized controlled trial.
    BY-BAND: Gastric BYpass or adjustable gastric BANDing surgery to treat morbid obesity: a multi-centre randomized controlled trial.
  • 2015 Diabetes Research and Wellness Foundation
    Is high intensity interval training (HIT) an efficient and effective form of exercise for people with Type 1 Diabetes?
  • 2015 ACTID Follow up: A 3 year follow up of patients who took part in the Early ACTID study.
    ACTID Follow up: A 3 year follow up of patients who took part in the Early ACTID study.
  • 2015 NIHR
    Development of a brief evidence-based tool to assess dietary intake and promote healthy dietary change for people with Type 2 diabetes
  • 2014 World Cancer Research Fund
    Personal and Environmental Determinants of Children's Health (PEACH3).
  • 2014 Increasing physical exercise to preserve beta cell function in adult patients with type 1 diabetes mellitus (T1DM): a pilot study (ExTOD) (Joint Chief investigator).
    Increasing physical exercise to preserve beta cell function in adult patients with type 1 diabetes mellitus (T1DM): a pilot study (ExTOD) (Joint Chief investigator).
  • 2011 Above and Beyond Grant UBHT special Trustees
    Baseline micronutrient status of people newly diagnosed with Type 2 diabetes enrolling in a diet and exercise trial (the Early ACTID Study).
  • 2011 Diabetes Research and Wellness Foundation
    Does the GLP-1 and GIP response predict who responds to bariatric surgery?
  • 2010 Primary care grant
    Pilot follow up of “Early ACTID” patients* (Chief Investigator).
  • 2009 Diabetes UK
    Continuation of “A randomised controlled trial of the benefits of exercise early in the management of Type 2 diabetes – “Early ACTID”” (Chief Investigator).
  • 2009 British Heart Foundation
    Inflammation in Cardiovascular Disease: Does physical activity improve pro- and anti-atherogenic inflammation in newly diagnosed Type 2 Diabetes?
  • 2007 Diabetes UK
    A randomised controlled trial of the benefits of exercise early in the management of Type 2 diabetes – “Early ACTID” (Chief Investigator).
  • 2005 Diabetes Research and Wellness Foundation
    Developing a technique to study the insulin signalling pathway ex-vivo in man (Chief Investigator).

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Narendran P, Jackson N, Daley A, Thompson D, Stokes K, Greenfield S, Charlton M, Curran M, Solomon TPJ, Nouwen A, et al (In Press). Exercise to preserve β-cell function in recent-onset Type 1 diabetes mellitus (EXTOD) - a randomized controlled pilot trial. Diabet Med, 34(11), 1521-1531. Abstract.  Author URL.
Rogers CA, Reeves BC, Byrne J, Donovan JL, Mazza G, Paramasivan S, Andrews RC, Wordsworth S, Thompson J, Blazeby JM, et al (2017). Adaptation of the By-Band randomized clinical trial to By-Band-Sleeve to include a new intervention and maintain relevance of the study to practice. British Journal of Surgery, 104(9), 1207-1214.
England CY, Thompson JL, Jago R, Cooper AR, Andrews RC (2017). Development of a brief, reliable and valid diet assessment tool for impaired glucose tolerance and diabetes: the UK Diabetes and Diet Questionnaire. PUBLIC HEALTH NUTRITION, 20(2), 191-199. Author URL.
Paramasivan S, Rogers CA, Welbourn R, Byrne JP, Salter N, Mahon D, Noble H, Kelly J, Mazza G, Whybrow P, et al (2017). Enabling recruitment success in bariatric surgical trials: pilot phase of the By-Band-Sleeve study. International Journal of Obesity, 41(11), 1654-1661.
Ali MA, Liu Y-F, Arif S, Tatovic D, Shariff H, Gibson VB, Yusuf N, Baptista R, Eichmann M, Petrov N, et al (2017). Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes. SCIENCE TRANSLATIONAL MEDICINE, 9(402). Author URL.
Brocklebank LA, Andrews RC, Page A, Falconer CL, Leary S, Cooper A (2017). The Acute Effects of Breaking up Seated Office Work with Standing or Light-Intensity Walking on Interstitial Glucose Concentration: a Randomized Crossover Trial. Journal of Physical Activity and Health, 14(8), 617-625.
Doble B, Wordsworth S, Rogers CA, Welbourn R, Byrne J, Blazeby JM (2017). What Are the Real Procedural Costs of Bariatric Surgery? a Systematic Literature Review of Published Cost Analyses. Obesity Surgery, 27(8), 2179-2192.
Coulman KD, Hopkins J, Brookes ST, Chalmers K, Main B, Owen-Smith A, Andrews RC, Byrne J, Donovan JL, Mazza G, et al (2016). A Core Outcome Set for the Benefits and Adverse Events of Bariatric and Metabolic Surgery: the BARIACT Project. PLOS MEDICINE, 13(11). Author URL.
Tatovic D, Luzio S, Dunseath G, Liu Y, Alhadj Ali M, Peakman M, Dayan CM (2016). Stimulated urine C-peptide creatinine ratio vs serum C-peptide level for monitoring of β-cell function in the first year after diagnosis of Type 1 diabetes. Diabetic Medicine, 33(11), 1564-1568.
Arora T, Chen MZ, Cooper AR, Andrews RC, Taheri S (2016). The Impact of Sleep Debt on Excess Adiposity and Insulin Sensitivity in Patients with Early Type 2 Diabetes Mellitus. JOURNAL OF CLINICAL SLEEP MEDICINE, 12(5), 673-680. Author URL.
England CY, Thompson JL, Jago R, Andrews RC (2015). A new dietary questionnaire for clinical use with people with Type 2 diabetes is repeatable and comparable with food diaries: introducing the Bristol Diabetes and Diet Questionnaire. DIABETIC MEDICINE, 32, 141-141. Author URL.
England CY, Andrews RC, Jago R, Thompson JL (2015). A systematic review of brief dietary questionnaires suitable for clinical use in the prevention and management of obesity, cardiovascular disease and type 2 diabetes. European Journal of Clinical Nutrition, 69(9), 977-1003.
Arora T, Chen MZ, Omar OM, Cooper AR, Andrews RC, Taheri S (2015). An investigation of the associations among sleep duration and quality, body mass index and insulin resistance in newly diagnosed type 2 diabetes mellitus patients. Therapeutic Advances in Endocrinology and Metabolism, 7(1), 3-11.
Chen MZ, Hudson CA, Vincent EE, de Berker DAR, May MT, Hers I, Dayan CM, Andrews RC, Tavaré JM (2015). Bariatric surgery in morbidly obese insulin resistant humans normalises insulin signalling but not insulin-stimulated glucose disposal. PLoS One, 10(4). Abstract.  Author URL.
Leiter LA, Astrup A, Andrews RC, Cuevas A, Horn DB, Kunešová M, Wittert G, Finer N (2015). Identification of educational needs in the management of overweight and obesity: results of an international survey of attitudes and practice. Clinical Obesity, 5(5), 245-255.
FALCONER CL, PAGE AS, ANDREWS RC, COOPER AR (2015). The Potential Impact of Displacing Sedentary Time in Adults with Type 2 Diabetes. Medicine & Science in Sports & Exercise, 47(10), 2070-2075.
Emadian A, Andrews RC, England CY, Wallace V, Thompson JL (2015). The effect of macronutrients on glycaemic control: a systematic review of dietary randomised controlled trials in overweight and obese adults with type 2 diabetes in which there was no difference in weight loss between treatment groups. British Journal of Nutrition, 114(10), 1656-1666.
Hopkins J, Howes N, Chalmers K, Whale K, Savovic J, Coulman K, Nicholson A, Byrne J, Whistance R, Welbourn R, et al (2015). What are important outcomes of bariatric surgery? an in-depth analysis to inform the development of a core outcome set and a comparison between the views of surgeons and other health professionals (the BARIACT study). Lancet, 385 Suppl 1 Abstract.  Author URL.
Lascar N, Kennedy A, Hancock B, Jenkins D, Andrews RC, Greenfield S, Narendran P (2014). Attitudes and Barriers to Exercise in Adults with Type 1 Diabetes (T1DM) and How Best to Address Them: a Qualitative Study. PLoS ONE, 9(9), e108019-e108019.
England CY, Andrews R, Jago R, Thompson JL (2014). Changes in reported food intake in adults with type 2 diabetes in response to a nonprescriptive dietary intervention. J Hum Nutr Diet, 27(4), 311-321. Abstract.  Author URL.
England CY, Thompson JL, Jago R, Cooper AR, Andrews RC (2014). Dietary changes and associations with metabolic improvements in adults with type 2 diabetes during a patient-centred dietary intervention: an exploratory analysis. BMJ Open, 4(6). Abstract.  Author URL.
Thompson D, Walhin J-P, Batterham AM, Stokes KA, Cooper AR, Andrews RC (2014). Effect of Diet or Diet Plus Physical Activity Versus Usual Care on Inflammatory Markers in Patients with Newly Diagnosed Type 2 Diabetes: the Early ACTivity in Diabetes (ACTID) Randomized, Controlled Trial. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 3(3). Author URL.
Hopkins JC, Howes N, Chalmers K, Savovic J, Whale K, Coulman KD, Welbourn R, Whistance RN, Andrews RC, Byrne JP, et al (2014). Outcome reporting in bariatric surgery: an in-depth analysis to inform the development of a core outcome set, the BARIACT Study. Obesity Reviews, 16(1), 88-106.
Falconer CL, Cooper AR, Walhin JP, Thompson D, Page AS, Peters TJ, Montgomery AA, Sharp DJ, Dayan CM, Andrews RC, et al (2014). Sedentary time and markers of inflammation in people with newly diagnosed type 2 diabetes. Nutr Metab Cardiovasc Dis, 24(9), 956-962. Abstract.  Author URL.
Rogers CA, Welbourn R, Byrne J, Donovan JL, Reeves BC, Wordsworth S, Andrews R, Thompson JL, Roderick P, Mahon D, et al (2014). The By-Band study: gastric bypass or adjustable gastric band surgery to treat morbid obesity: study protocol for a multi-centre randomised controlled trial with an internal pilot phase. Trials, 15 Abstract.  Author URL.
Narendran P, Solomon TP, Kennedy A, Chimen M, Andrews RC (2014). The time has come to test the beta cell preserving effects of exercise in patients with new onset type 1 diabetes. Diabetologia, 58(1), 10-18.
Andrews RC, Chen MZ, Logue J (2014). ‘Bariatric surgery for type 2 diabetes always produces a good outcome’. Practical Diabetes, 31(9), 376-380.
Kennedy A, Nirantharakumar K, Chimen M, Pang TT, Hemming K, Andrews RC, Narendran P (2013). Does Exercise Improve Glycaemic Control in Type 1 Diabetes? a Systematic Review and Meta-Analysis. PLoS ONE, 8(3), e58861-e58861.
Lascar N, Kennedy A, Jackson N, Daley A, Dowswell G, Thompson D, Stokes K, Greenfield S, Holder R, Andrews R, et al (2013). Exercise to preserve beta cell function in recent-onset type 1 diabetes mellitus (EXTOD) - a study protocol for a pilot randomized controlled trial. TRIALS, 14 Author URL.  Full text.
Coulman KD, Abdelrahman T, Owen-Smith A, Andrews RC, Welbourn R, Blazeby JM (2013). Patient-reported outcomes in bariatric surgery: a systematic review of standards of reporting. Obes Rev, 14(9), 707-720. Abstract.  Author URL.
Kennedy A, Dowswell G, Andrews R, Greenfield S, Narendran P (2013). What are the barriers to exercise in patients newly diagnosed with Type 1 diabetes?. DIABETIC MEDICINE, 30, 124-124. Author URL.
Stokes KA, Gilbert KL, Hall GM, Andrews RC, Thompson D (2012). Different responses of selected hormones to three types of exercise in young men. European Journal of Applied Physiology, 113(3), 775-783.
Cooper AR, Sebire S, Montgomery AA, Peters TJ, Sharp DJ, Jackson N, Fitzsimons K, Dayan CM, Andrews RC (2012). Sedentary time, breaks in sedentary time and metabolic variables in people with newly diagnosed type 2 diabetes. Diabetologia, 55(3), 589-599. Abstract.  Author URL.
Chimen M, Kennedy A, Nirantharakumar K, Pang TT, Andrews R, Narendran P (2012). What are the health benefits of physical activity in type 1 diabetes mellitus? a literature review. DIABETOLOGIA, 55(3), 542-551. Author URL.
Andrews RC, Cooper AR, Montgomery AA, Peters TJ, Sharp DJ, Dayan CM (2011). Diet or diet plus physical activity in patients with early type 2 diabetes Reply. LANCET, 378(9809), 2067-2068. Author URL.
Andrews RC, Cooper AR, Montgomery AA, Norcross AJ, Peters TJ, Sharp DJ, Jackson N, Fitzsimons K, Bright J, Coulman K, et al (2011). Diet or diet plus physical activity versus usual care in patients with newly diagnosed type 2 diabetes: the Early ACTID randomised controlled trial. Lancet, 378(9786), 129-139. Abstract.  Author URL.
Pournaras DJ, Aasheim ET, Søvik TT, Andrews R, Mahon D, Welbourn R, Olbers T, le Roux CW (2011). Effect of the definition of type II diabetes remission in the evaluation of bariatric surgery for metabolic disorders. British Journal of Surgery, 99(1), 100-103.
Idris I, Hall AP, O'Reilly J, Barnett A, Allen M, Andrews R, Grunstein P, Lewis K, Goenka N, Wilding JP, et al (2009). Obstructive sleep apnoea in patients with type 2 diabetes: aetiology and implications for clinical care. DIABETES OBESITY & METABOLISM, 11(8), 733-741. Author URL.
Malpass A, Andrews R, Turner KM (2009). Patients with Type 2 Diabetes experiences of making multiple lifestyle changes: a qualitative study. Patient Educ Couns, 74(2), 258-263. Abstract.  Author URL.
Pang TTL, Kiyani S, Boora U, Gough SCL, Andrews R, Narendran P (2008). Adipocytokines and their receptors are expressed by peripheral blood mononuclear cells (PBMCs), and this expression is modified by exercise-induced weight loss. IMMUNOLOGY, 125, 108-109. Author URL.
Sandeep TC, Andrew R, Homer NZM, Andrews RC, Smith K, Walker BR (2005). Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone. Diabetes, 54(3), 872-879. Abstract.  Author URL.
Andrews RC, Rooyackers O, Walker BR (2003). Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes. J Clin Endocrinol Metab, 88(1), 285-291. Abstract.  Author URL.
Andrews RC, Herlihy O, Livingstone DEW, Andrew R, Walker BR (2002). Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance. J Clin Endocrinol Metab, 87(12), 5587-5593. Abstract.  Author URL.
Holland JB, Furness JT, Griffiths SA, Mudge E, Parfitt VJ, Andrews RC (2001). 1 hour a week of exercise is enough: a study of a 3 and 6 month exercise program in patients with diabetes. DIABETOLOGIA, 44, A254-A254. Author URL.
McIntyre CA, Buckley CH, Jones GC, Sandeep TC, Andrews RC, Elliott AI, Gray GA, Williams BC, McKnight JA, Walker BR, et al (2001). Endothelium-derived hyperpolarizing factor and potassium use different mechanisms to induce relaxation of human subcutaneous resistance arteries. Br J Pharmacol, 133(6), 902-908. Abstract.  Author URL.
Andrews RC, Lightman SL (2000). A better use of corticosteroids. The Practitioner, 1613, 667-667.
Finken MJ, Andrews RC, Andrew R, Walker BR (1999). Cortisol metabolism in healthy young adults: sexual dimorphism in activities of A-ring reductases, but not 11beta-hydroxysteroid dehydrogenases. J Clin Endocrinol Metab, 84(9), 3316-3321. Abstract.  Author URL.
Andrews RC, Walker BR (1999). Glucocorticoids and insulin resistance: old hormones, new targets. Clin Sci (Lond), 96(5), 513-523. Abstract.  Author URL.

Conferences

England CY, Cooper AR, Andrews RC (2017). Dietary vitamin D intake and supplement use in people at high risk of, or newly diagnosed with, Type 2 diabetes in 2014-2015 in the South West of England.  Author URL.
Ali MA, Liu Y-F, Stenson R, Leech N, Andrews R, Peakman M, Dayan C (2016). Proinsulin peptide immunotherapy in new-onset type 1 diabetes is well-tolerated and associated with reduced daffy insulin usage.  Author URL.
Ali MA, Liu Y-F, Stenson R, Clifford G, Adams L, Powrie J, Kyne D, Leech N, Green K, Andrews R, et al (2015). Proinsulin peptide immunotherapy in type 1 diabetes: safety data of a first in new-onset type 1 diabetes phase 1b trial.  Author URL.
Chen MZ, Greenwood RJ, Le Roux C, Andrews RC (2015). Weight loss contributes more to the glycaemic improvement seen with bariatric surgery than GLP-1.  Author URL.
Chen MZ, Greenwood R, Andrews RC (2014). Slow but steady weight loss is better than rapid weight loss at normalising glycaemia after bariatric surgery: the tortoise beats the hare.  Author URL.
Coulman KD, Owen-Smith A, Andrews RC, Chalmers K, Ferguson Y, Norton S, Welbourn R, Whale K, Blazeby JM (2014). THE PATIENT PERSPECTIVE OF BARIATRIC SURGERY OUTCOMES: DEVELOPING a 'CORE' SET OF PATIENT-REPORTED OUTCOMES.  Author URL.
Abdelrahman T, Coulman K, Owen-Smith A, Andrews RC, Welbourn R, Blazeby JM (2013). Health related quality of life reporting in bariatric surgery: a systematic review of current practice.  Author URL.
Coulman K, Owen-Smith A, Andrews R, Norton S, Welbourn R, Blazeby J (2013). The patient perspective of outcomes of bariatric surgery: the need for a 'core' set of patient-reported outcomes.  Author URL.
Coulman K, Abdelrahman T, Owen-Smith A, Andrews R, Welbourn R, Blazeby J (2012). Measuring patient reported outcomes in bariatric surgery: standards of reporting and synthesis with clinical data.  Author URL.
Hopkins J, Andrews R, Byrne J, Donovan J, Reeves B, Roderick P, Rogers C, Thompson J, Welbourn R, Wordsworth S, et al (2012). Reporting clinical outcomes of bariatric surgery: the need for a core outcome set.  Author URL.
Bennett-Britton I, Kingsly A, White P, Jackson NA, Chen MZ, Andrews RC (2011). Effects of diet and diet plus physical activity on psychological outcomes in newly diagnosed type 2 diabetes mellitus: results of a randomised controlled trial.  Author URL.
Parker R, Guthrie N, Patel N, Woltersdorf W, Andrews R, Dayan CM, ACTID E (2011). PREVALENCE OF ABNORMAL LIVER FUNCTION AND RESPONSE TO LIFESTYLE INTERVENTIONS IN NEWLY DIAGNOSED TYPE 2 DIABETES: PRELIMINARY RESULTS OF a UK RANDOMISED CONTROLLED STUDY.  Author URL.
Parker R, Guthrie N, Patel N, Woltersdorf W, Andrews R, Dayan C, McCune CA, ACTID E (2011). PREVALENCE OF ABNORMAL LIVER FUNCTION AND RESPONSE TO LIFESTYLE INTERVENTIONS IN NEWLY DIAGNOSED TYPE 2 DIABETES: PRELIMINARY RESULTS OF a UK RANDOMISED CONTROLLED STUDY.  Author URL.
Pang TTL, Goble E, Weaver K, Chinem M, Eldershaw SA, Gough SC, Andrews R, Narendran P (2009). Adiponectin receptor expression on peripheral blood mononuclear cells is reduced in autoimmune diabetes and can be upregulated with lifestyle intervention.  Author URL.
Norcross AJ, Andrews RC, Actid E (2007). Misdiagnosis of Type 2 diabetes in the southwest of England.  Author URL.
Fitzsimons KJ, Cooper AR, Andrews R (2007). Physical activity in adults with newly diagnosed Type 2 diabetes: the early ACTID Study.  Author URL.
Chen MZ, Hudson CA, Vincent EE, Dayan CM, DeBerker D, Tavare JM, Andrews RC (2007). Weight loss resulting from bariatric surgery in morbidly obese insulin resistant individuals leads to improvements in insulin signaling.  Author URL.
Andrews RC, Chau WF, Allen SE, Douek IF (2005). Women after gestational diabetes - does the adrenal gland play a role in the future development of type 2 diabetes?.  Author URL.
McIntyre CA, Andrews RC, Elliot A, Gray GA, Williams BC, McKnight JA, Walker BR, Hadoke PWF (1998). Endothelium-derived hyperpolarizing factor mediates to a large extent acetylcholine-induced relaxation of human subcutaneous resistance arteries.  Author URL.

Publications by year


In Press

Narendran P, Jackson N, Daley A, Thompson D, Stokes K, Greenfield S, Charlton M, Curran M, Solomon TPJ, Nouwen A, et al (In Press). Exercise to preserve β-cell function in recent-onset Type 1 diabetes mellitus (EXTOD) - a randomized controlled pilot trial. Diabet Med, 34(11), 1521-1531. Abstract.  Author URL.

2017

Rogers CA, Reeves BC, Byrne J, Donovan JL, Mazza G, Paramasivan S, Andrews RC, Wordsworth S, Thompson J, Blazeby JM, et al (2017). Adaptation of the By-Band randomized clinical trial to By-Band-Sleeve to include a new intervention and maintain relevance of the study to practice. British Journal of Surgery, 104(9), 1207-1214.
England CY, Thompson JL, Jago R, Cooper AR, Andrews RC (2017). Development of a brief, reliable and valid diet assessment tool for impaired glucose tolerance and diabetes: the UK Diabetes and Diet Questionnaire. PUBLIC HEALTH NUTRITION, 20(2), 191-199. Author URL.
England CY, Cooper AR, Andrews RC (2017). Dietary vitamin D intake and supplement use in people at high risk of, or newly diagnosed with, Type 2 diabetes in 2014-2015 in the South West of England.  Author URL.
Paramasivan S, Rogers CA, Welbourn R, Byrne JP, Salter N, Mahon D, Noble H, Kelly J, Mazza G, Whybrow P, et al (2017). Enabling recruitment success in bariatric surgical trials: pilot phase of the By-Band-Sleeve study. International Journal of Obesity, 41(11), 1654-1661.
Ali MA, Liu Y-F, Arif S, Tatovic D, Shariff H, Gibson VB, Yusuf N, Baptista R, Eichmann M, Petrov N, et al (2017). Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes. SCIENCE TRANSLATIONAL MEDICINE, 9(402). Author URL.
Brocklebank LA, Andrews RC, Page A, Falconer CL, Leary S, Cooper A (2017). The Acute Effects of Breaking up Seated Office Work with Standing or Light-Intensity Walking on Interstitial Glucose Concentration: a Randomized Crossover Trial. Journal of Physical Activity and Health, 14(8), 617-625.
Doble B, Wordsworth S, Rogers CA, Welbourn R, Byrne J, Blazeby JM (2017). What Are the Real Procedural Costs of Bariatric Surgery? a Systematic Literature Review of Published Cost Analyses. Obesity Surgery, 27(8), 2179-2192.

2016

Coulman KD, Hopkins J, Brookes ST, Chalmers K, Main B, Owen-Smith A, Andrews RC, Byrne J, Donovan JL, Mazza G, et al (2016). A Core Outcome Set for the Benefits and Adverse Events of Bariatric and Metabolic Surgery: the BARIACT Project. PLOS MEDICINE, 13(11). Author URL.
Ali MA, Liu Y-F, Stenson R, Leech N, Andrews R, Peakman M, Dayan C (2016). Proinsulin peptide immunotherapy in new-onset type 1 diabetes is well-tolerated and associated with reduced daffy insulin usage.  Author URL.
Tatovic D, Luzio S, Dunseath G, Liu Y, Alhadj Ali M, Peakman M, Dayan CM (2016). Stimulated urine C-peptide creatinine ratio vs serum C-peptide level for monitoring of β-cell function in the first year after diagnosis of Type 1 diabetes. Diabetic Medicine, 33(11), 1564-1568.
Arora T, Chen MZ, Cooper AR, Andrews RC, Taheri S (2016). The Impact of Sleep Debt on Excess Adiposity and Insulin Sensitivity in Patients with Early Type 2 Diabetes Mellitus. JOURNAL OF CLINICAL SLEEP MEDICINE, 12(5), 673-680. Author URL.

2015

England CY, Thompson JL, Jago R, Andrews RC (2015). A new dietary questionnaire for clinical use with people with Type 2 diabetes is repeatable and comparable with food diaries: introducing the Bristol Diabetes and Diet Questionnaire. DIABETIC MEDICINE, 32, 141-141. Author URL.
England CY, Andrews RC, Jago R, Thompson JL (2015). A systematic review of brief dietary questionnaires suitable for clinical use in the prevention and management of obesity, cardiovascular disease and type 2 diabetes. European Journal of Clinical Nutrition, 69(9), 977-1003.
Arora T, Chen MZ, Omar OM, Cooper AR, Andrews RC, Taheri S (2015). An investigation of the associations among sleep duration and quality, body mass index and insulin resistance in newly diagnosed type 2 diabetes mellitus patients. Therapeutic Advances in Endocrinology and Metabolism, 7(1), 3-11.
Chen MZ, Hudson CA, Vincent EE, de Berker DAR, May MT, Hers I, Dayan CM, Andrews RC, Tavaré JM (2015). Bariatric surgery in morbidly obese insulin resistant humans normalises insulin signalling but not insulin-stimulated glucose disposal. PLoS One, 10(4). Abstract.  Author URL.
Leiter LA, Astrup A, Andrews RC, Cuevas A, Horn DB, Kunešová M, Wittert G, Finer N (2015). Identification of educational needs in the management of overweight and obesity: results of an international survey of attitudes and practice. Clinical Obesity, 5(5), 245-255.
Ali MA, Liu Y-F, Stenson R, Clifford G, Adams L, Powrie J, Kyne D, Leech N, Green K, Andrews R, et al (2015). Proinsulin peptide immunotherapy in type 1 diabetes: safety data of a first in new-onset type 1 diabetes phase 1b trial.  Author URL.
FALCONER CL, PAGE AS, ANDREWS RC, COOPER AR (2015). The Potential Impact of Displacing Sedentary Time in Adults with Type 2 Diabetes. Medicine & Science in Sports & Exercise, 47(10), 2070-2075.
Emadian A, Andrews RC, England CY, Wallace V, Thompson JL (2015). The effect of macronutrients on glycaemic control: a systematic review of dietary randomised controlled trials in overweight and obese adults with type 2 diabetes in which there was no difference in weight loss between treatment groups. British Journal of Nutrition, 114(10), 1656-1666.
Chen MZ, Greenwood RJ, Le Roux C, Andrews RC (2015). Weight loss contributes more to the glycaemic improvement seen with bariatric surgery than GLP-1.  Author URL.
Hopkins J, Howes N, Chalmers K, Whale K, Savovic J, Coulman K, Nicholson A, Byrne J, Whistance R, Welbourn R, et al (2015). What are important outcomes of bariatric surgery? an in-depth analysis to inform the development of a core outcome set and a comparison between the views of surgeons and other health professionals (the BARIACT study). Lancet, 385 Suppl 1 Abstract.  Author URL.

2014

Lascar N, Kennedy A, Hancock B, Jenkins D, Andrews RC, Greenfield S, Narendran P (2014). Attitudes and Barriers to Exercise in Adults with Type 1 Diabetes (T1DM) and How Best to Address Them: a Qualitative Study. PLoS ONE, 9(9), e108019-e108019.
England CY, Andrews R, Jago R, Thompson JL (2014). Changes in reported food intake in adults with type 2 diabetes in response to a nonprescriptive dietary intervention. J Hum Nutr Diet, 27(4), 311-321. Abstract.  Author URL.
England CY, Thompson JL, Jago R, Cooper AR, Andrews RC (2014). Dietary changes and associations with metabolic improvements in adults with type 2 diabetes during a patient-centred dietary intervention: an exploratory analysis. BMJ Open, 4(6). Abstract.  Author URL.
Thompson D, Walhin J-P, Batterham AM, Stokes KA, Cooper AR, Andrews RC (2014). Effect of Diet or Diet Plus Physical Activity Versus Usual Care on Inflammatory Markers in Patients with Newly Diagnosed Type 2 Diabetes: the Early ACTivity in Diabetes (ACTID) Randomized, Controlled Trial. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 3(3). Author URL.
Hopkins JC, Howes N, Chalmers K, Savovic J, Whale K, Coulman KD, Welbourn R, Whistance RN, Andrews RC, Byrne JP, et al (2014). Outcome reporting in bariatric surgery: an in-depth analysis to inform the development of a core outcome set, the BARIACT Study. Obesity Reviews, 16(1), 88-106.
Falconer CL, Cooper AR, Walhin JP, Thompson D, Page AS, Peters TJ, Montgomery AA, Sharp DJ, Dayan CM, Andrews RC, et al (2014). Sedentary time and markers of inflammation in people with newly diagnosed type 2 diabetes. Nutr Metab Cardiovasc Dis, 24(9), 956-962. Abstract.  Author URL.
Chen MZ, Greenwood R, Andrews RC (2014). Slow but steady weight loss is better than rapid weight loss at normalising glycaemia after bariatric surgery: the tortoise beats the hare.  Author URL.
Coulman KD, Owen-Smith A, Andrews RC, Chalmers K, Ferguson Y, Norton S, Welbourn R, Whale K, Blazeby JM (2014). THE PATIENT PERSPECTIVE OF BARIATRIC SURGERY OUTCOMES: DEVELOPING a 'CORE' SET OF PATIENT-REPORTED OUTCOMES.  Author URL.
Rogers CA, Welbourn R, Byrne J, Donovan JL, Reeves BC, Wordsworth S, Andrews R, Thompson JL, Roderick P, Mahon D, et al (2014). The By-Band study: gastric bypass or adjustable gastric band surgery to treat morbid obesity: study protocol for a multi-centre randomised controlled trial with an internal pilot phase. Trials, 15 Abstract.  Author URL.
Narendran P, Solomon TP, Kennedy A, Chimen M, Andrews RC (2014). The time has come to test the beta cell preserving effects of exercise in patients with new onset type 1 diabetes. Diabetologia, 58(1), 10-18.
Andrews RC, Chen MZ, Logue J (2014). ‘Bariatric surgery for type 2 diabetes always produces a good outcome’. Practical Diabetes, 31(9), 376-380.

2013

Kennedy A, Nirantharakumar K, Chimen M, Pang TT, Hemming K, Andrews RC, Narendran P (2013). Does Exercise Improve Glycaemic Control in Type 1 Diabetes? a Systematic Review and Meta-Analysis. PLoS ONE, 8(3), e58861-e58861.
Lascar N, Kennedy A, Jackson N, Daley A, Dowswell G, Thompson D, Stokes K, Greenfield S, Holder R, Andrews R, et al (2013). Exercise to preserve beta cell function in recent-onset type 1 diabetes mellitus (EXTOD) - a study protocol for a pilot randomized controlled trial. TRIALS, 14 Author URL.  Full text.
Abdelrahman T, Coulman K, Owen-Smith A, Andrews RC, Welbourn R, Blazeby JM (2013). Health related quality of life reporting in bariatric surgery: a systematic review of current practice.  Author URL.
Coulman KD, Abdelrahman T, Owen-Smith A, Andrews RC, Welbourn R, Blazeby JM (2013). Patient-reported outcomes in bariatric surgery: a systematic review of standards of reporting. Obes Rev, 14(9), 707-720. Abstract.  Author URL.
Coulman K, Owen-Smith A, Andrews R, Norton S, Welbourn R, Blazeby J (2013). The patient perspective of outcomes of bariatric surgery: the need for a 'core' set of patient-reported outcomes.  Author URL.
Kennedy A, Dowswell G, Andrews R, Greenfield S, Narendran P (2013). What are the barriers to exercise in patients newly diagnosed with Type 1 diabetes?. DIABETIC MEDICINE, 30, 124-124. Author URL.

2012

Stokes KA, Gilbert KL, Hall GM, Andrews RC, Thompson D (2012). Different responses of selected hormones to three types of exercise in young men. European Journal of Applied Physiology, 113(3), 775-783.
Coulman K, Abdelrahman T, Owen-Smith A, Andrews R, Welbourn R, Blazeby J (2012). Measuring patient reported outcomes in bariatric surgery: standards of reporting and synthesis with clinical data.  Author URL.
Hopkins J, Andrews R, Byrne J, Donovan J, Reeves B, Roderick P, Rogers C, Thompson J, Welbourn R, Wordsworth S, et al (2012). Reporting clinical outcomes of bariatric surgery: the need for a core outcome set.  Author URL.
Cooper AR, Sebire S, Montgomery AA, Peters TJ, Sharp DJ, Jackson N, Fitzsimons K, Dayan CM, Andrews RC (2012). Sedentary time, breaks in sedentary time and metabolic variables in people with newly diagnosed type 2 diabetes. Diabetologia, 55(3), 589-599. Abstract.  Author URL.
Chimen M, Kennedy A, Nirantharakumar K, Pang TT, Andrews R, Narendran P (2012). What are the health benefits of physical activity in type 1 diabetes mellitus? a literature review. DIABETOLOGIA, 55(3), 542-551. Author URL.

2011

Andrews RC, Cooper AR, Montgomery AA, Peters TJ, Sharp DJ, Dayan CM (2011). Diet or diet plus physical activity in patients with early type 2 diabetes Reply. LANCET, 378(9809), 2067-2068. Author URL.
Andrews RC, Cooper AR, Montgomery AA, Norcross AJ, Peters TJ, Sharp DJ, Jackson N, Fitzsimons K, Bright J, Coulman K, et al (2011). Diet or diet plus physical activity versus usual care in patients with newly diagnosed type 2 diabetes: the Early ACTID randomised controlled trial. Lancet, 378(9786), 129-139. Abstract.  Author URL.
Pournaras DJ, Aasheim ET, Søvik TT, Andrews R, Mahon D, Welbourn R, Olbers T, le Roux CW (2011). Effect of the definition of type II diabetes remission in the evaluation of bariatric surgery for metabolic disorders. British Journal of Surgery, 99(1), 100-103.
Bennett-Britton I, Kingsly A, White P, Jackson NA, Chen MZ, Andrews RC (2011). Effects of diet and diet plus physical activity on psychological outcomes in newly diagnosed type 2 diabetes mellitus: results of a randomised controlled trial.  Author URL.
Parker R, Guthrie N, Patel N, Woltersdorf W, Andrews R, Dayan CM, ACTID E (2011). PREVALENCE OF ABNORMAL LIVER FUNCTION AND RESPONSE TO LIFESTYLE INTERVENTIONS IN NEWLY DIAGNOSED TYPE 2 DIABETES: PRELIMINARY RESULTS OF a UK RANDOMISED CONTROLLED STUDY.  Author URL.
Parker R, Guthrie N, Patel N, Woltersdorf W, Andrews R, Dayan C, McCune CA, ACTID E (2011). PREVALENCE OF ABNORMAL LIVER FUNCTION AND RESPONSE TO LIFESTYLE INTERVENTIONS IN NEWLY DIAGNOSED TYPE 2 DIABETES: PRELIMINARY RESULTS OF a UK RANDOMISED CONTROLLED STUDY.  Author URL.

2009

Pang TTL, Goble E, Weaver K, Chinem M, Eldershaw SA, Gough SC, Andrews R, Narendran P (2009). Adiponectin receptor expression on peripheral blood mononuclear cells is reduced in autoimmune diabetes and can be upregulated with lifestyle intervention.  Author URL.
Idris I, Hall AP, O'Reilly J, Barnett A, Allen M, Andrews R, Grunstein P, Lewis K, Goenka N, Wilding JP, et al (2009). Obstructive sleep apnoea in patients with type 2 diabetes: aetiology and implications for clinical care. DIABETES OBESITY & METABOLISM, 11(8), 733-741. Author URL.
Malpass A, Andrews R, Turner KM (2009). Patients with Type 2 Diabetes experiences of making multiple lifestyle changes: a qualitative study. Patient Educ Couns, 74(2), 258-263. Abstract.  Author URL.

2008

Pang TTL, Kiyani S, Boora U, Gough SCL, Andrews R, Narendran P (2008). Adipocytokines and their receptors are expressed by peripheral blood mononuclear cells (PBMCs), and this expression is modified by exercise-induced weight loss. IMMUNOLOGY, 125, 108-109. Author URL.

2007

Norcross AJ, Andrews RC, Actid E (2007). Misdiagnosis of Type 2 diabetes in the southwest of England.  Author URL.
Fitzsimons KJ, Cooper AR, Andrews R (2007). Physical activity in adults with newly diagnosed Type 2 diabetes: the early ACTID Study.  Author URL.
Chen MZ, Hudson CA, Vincent EE, Dayan CM, DeBerker D, Tavare JM, Andrews RC (2007). Weight loss resulting from bariatric surgery in morbidly obese insulin resistant individuals leads to improvements in insulin signaling.  Author URL.

2005

Sandeep TC, Andrew R, Homer NZM, Andrews RC, Smith K, Walker BR (2005). Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone. Diabetes, 54(3), 872-879. Abstract.  Author URL.
Andrews RC, Chau WF, Allen SE, Douek IF (2005). Women after gestational diabetes - does the adrenal gland play a role in the future development of type 2 diabetes?.  Author URL.

2003

Andrews RC, Rooyackers O, Walker BR (2003). Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes. J Clin Endocrinol Metab, 88(1), 285-291. Abstract.  Author URL.

2002

Andrews RC, Herlihy O, Livingstone DEW, Andrew R, Walker BR (2002). Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance. J Clin Endocrinol Metab, 87(12), 5587-5593. Abstract.  Author URL.

2001

Holland JB, Furness JT, Griffiths SA, Mudge E, Parfitt VJ, Andrews RC (2001). 1 hour a week of exercise is enough: a study of a 3 and 6 month exercise program in patients with diabetes. DIABETOLOGIA, 44, A254-A254. Author URL.
McIntyre CA, Buckley CH, Jones GC, Sandeep TC, Andrews RC, Elliott AI, Gray GA, Williams BC, McKnight JA, Walker BR, et al (2001). Endothelium-derived hyperpolarizing factor and potassium use different mechanisms to induce relaxation of human subcutaneous resistance arteries. Br J Pharmacol, 133(6), 902-908. Abstract.  Author URL.

2000

Andrews RC, Lightman SL (2000). A better use of corticosteroids. The Practitioner, 1613, 667-667.

1999

Finken MJ, Andrews RC, Andrew R, Walker BR (1999). Cortisol metabolism in healthy young adults: sexual dimorphism in activities of A-ring reductases, but not 11beta-hydroxysteroid dehydrogenases. J Clin Endocrinol Metab, 84(9), 3316-3321. Abstract.  Author URL.
Andrews RC, Walker BR (1999). Glucocorticoids and insulin resistance: old hormones, new targets. Clin Sci (Lond), 96(5), 513-523. Abstract.  Author URL.

1998

McIntyre CA, Andrews RC, Elliot A, Gray GA, Williams BC, McKnight JA, Walker BR, Hadoke PWF (1998). Endothelium-derived hyperpolarizing factor mediates to a large extent acetylcholine-induced relaxation of human subcutaneous resistance arteries.  Author URL.

Rob_Andrews Details from cache as at 2018-08-21 02:27:02

Refresh publications

Awards

  • 1992 Bayer House Surgical Prize
  • 2011 Royal College of General Practitioners and Novartis Research Diabetes Paper of the Year Award
  • 2012 Rank Nutritoion Lecture Diabetes UK

Committee/panel activities

  • 2016 →

Chair of Diabetes Clinical Study Group 3: Prevention, targets & therapies for Type 2 diabetes

 

  • 2016 →

Member of Diabetes Research and Wellness Foundation research committee

 

  • 2015 →

Invited Panel member JDRF Peak (Type 1 Diabetes performance in Exercise and Knowledge).

 

  • 2012→

Invited member Royal College of Physicians Committee on Obesity.

 

  • 2011 to 2012

Lead Physician on NCEPOD investigation into Bariatric Surgery – Too Lean a Service?

 

  • 2011→2017

Member Diabetes UK research committee

 

  • 2011→

Member of International Association for the Study of Obesity, Education and Management Task Force

 


Editorial responsibilities

  • 2017 →

Member of Editorial Board of Clinical Endocrinology. 

 

 


Invited lectures

March 2017

RCP Annual conference 2017

March 2017

Diabetes UK Annual Conference 2017

February 2017

Irish Endocrine Society Annual conference

November 2016

British Dietitian Association Annual conference

November 2106

British Endocrine Society Annual conference

May 2016

Annual Sports and Exercise meeting

March 2016

Society for Endocrinology Clinical update course

March 2016

Diabetes UK Annual Conference 2016

January 2016

Clinical Conundrums for Consultant Diabetologists

November 2016

ALAMA Autumn Conference

October 2015

Scope Meeting Qatar

March 2015

Diabetes UK Annual Conference 2015

Jan 2015

Annual Bariatric Physician Meeting in London

Sept 2014

Endocrine for General Physician at Royal College of Physicians London

March 2014

Diabetes Ireland Annual Conference 2014

March 2014

Diabetes UK Annual Conference 2014

Dec 2013

IDF Melbourne, Australia

Nov 2013

Royal College of Physicians of Edinburgh

Sept 2013

National Dietitians Study Day

May 2013

Annual Primary Care Conference Birmingham

April 2013

Annual meeting YDF Irelend

Nov 2012

BESPOD national meeting

March 2012

Diabetes UK Annual Conference, Rank Nutrition Lecturer

March 2012

YDF meeting

Jan 2011

Association of Obesity Conference London

Oct 2011

Advanced Pump Course Cambridge

June 2011

American Diabetes Association Annual meeting

April  2011

British Endocrine Society Annual meeting

Sept 2010

British Endocrinology Society Obesity meeting Cambridge

March 2010

Diabetes UK annual Conference

Sept 2009

British Endocrinology Society Obesity meeting Cambridge

March 2009

British Endocrine Society

March 2008

Diabetes UK annual Conference

Sept 2004

“Obesity and the Lung” The Royal Society of Medicine, London

Jan 2004

Fifth National Pituitary Foundation Conference

Sept 2003

Advanced Diabetes Course

Nov 2002

The Irish Nutrition and Dietetic Institute

Sept 2002

Physical Activity and Medical Condition Conference, organised by Diabetes UK and British Heart Foundation.

March 2002

Diabetes UK annual Conference


Media Coverage


 

PhD supervisor

MRES supervisor

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