Rebecca DewhurstTrigg | The Medical School

Rebecca Dewhurst-Trigg

Postdoctoral Research Associate

R.E.Dewhurst-Trigg@exeter.ac.uk

RILD Building

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Overview

Dr Rebecca Dewhurst-Trigg graduated with a BSc (Hons) in Exercise and Sports Science from the University of Exeter which included time spent studying at Massey University, New Zealand. She then completed her MSc by Research in Sport and Health Science, also at the University of Exeter, where her thesis focused on investigating the effect of dietary nitrate supplementation on team sport performance.

Rebecca then completed her PhD at Loughborough University which investigated the nutritional modulation of inflammation, immune function and metabolic health. Her thesis specifically focused on exploring the effect of short-term excessive dietary fat intake on subcutaneous white adipose tissue nuclear factor-kappaB inflammatory signalling.

Following her PhD, Rebecca joined the research groups of Dr Martin Eichmann and Dr Chloe Rackham (2021-2023) at the University of Exeter as a full-time postdoctoral research associate (PDRA) and worked part-time split between both groups. One project focused on investigating T cell immunology in Type 1 diabetes (T1D) and the other project focused on improving islet survival, function, inflammation and transplantation outcomes using mesenchymal stem/stromal cells (MSC), respectively.

Rebecca is currently (2023) working as a PDRA with Dr Chloe Rackham on a research project aimed at exploring the islet-protective role for native pancreatic MSCs in health and T1D.

ORCiD: http://orcid.org/0000-0001-8940-1094

Qualifications

2013-2016 BSc (Hons) Exercise and Sports Science, University of Exeter

2016-2017 MSc by Research Sport and Health Science, University of Exeter

Thesis title: The effect of dietary nitrate supplementation on agility, linear sprint and vertial jump performance

2017-2020 PhD, School of Sport, Exercise and Health Sciences, Loughborough University

Thesis title: The effect of short-term excessive dietary fat intake on subcutaneous white adipose tissue nuclear factor-kappaB inflammatory signalling

Research

Research interests

Rebecca’s broad research interests lie within improving public health by understanding the molecular events underpinning health and disease as well as the role of interventions such as therapeutics, nutrition, and/or exercise in disease risk and disease prevention.

Publications

Journal articles

Dewhurst-Trigg R, Wadley AJ, Woods RM, Sherar LB, Bishop NC, Hulston CJ, Markey O (2020). Short-term High-fat Overfeeding Does Not Induce NF-κB Inflammatory Signaling in Subcutaneous White Adipose Tissue. J Clin Endocrinol Metab, 105(7). Abstract. Author URL.

Dewhurst-Trigg R, Hulston CJ, Markey O (2020). The effect of quantity and quality of dietary fat intake on subcutaneous white adipose tissue inflammatory responses. Proc Nutr Soc, 1-15. Abstract. Author URL.

Dewhurst-Trigg R, Yeates T, Blackwell JR, Thompson C, Linoby A, Morgan PT, Clarke I, Connolly LJ, Wylie LJ, Winyard PG, et al (2018). Lowering of blood pressure after nitrate-rich vegetable consumption is abolished with the co-ingestion of thiocyanate-rich vegetables in healthy normotensive males. Nitric Oxide, 74, 39-46. Abstract. Author URL.

Hulston CJ, Woods RM, Dewhurst-Trigg R, Parry SA, Gagnon S, Baker L, James LJ, Markey O, Martin NRW, Ferguson RA, et al (2018). Resistance exercise stimulates mixed muscle protein synthesis in lean and obese young adults. Physiol Rep, 6(14). Abstract. Author URL.

Conferences

Rackham CL, Dewhurst-Trigg RE, Hopkinson JR, Morgan NG, Richardson SJ, Jones PM (2022). Mesenchymal stromal cells and their secretory factors reduce the inflammatory crosstalk between pancreatic islets and endothelial cells. Author URL.

Dewhurst-Trigg R, Woods RM, Hulston CJ, Markey O (2020). Impact of high-fat overfeeding on white adipose tissue and systemic metabolic and inflammatory responses. Author URL.

External Engagement and Impact

Awards

Nutrition Society UK Postgraduate Competition Winner 2019
Undergraduate Free Communication Presentation Award, BASES Student Conference 2016

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