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Philip Mitchelmore

Philip Mitchelmore

Honorary Senior Clinical Lecturer

 Medical School Building 

 

Medical School Building, St Luke's Campus, Magdalen Road, Exeter, EX1 2LU, UK

Overview

Phil qualified in medicine from the Royal Free and University College London medical school before commencing his training as a physician. After achieving his Membership of the Royal College of Physicians, he worked in Intensive Care Medicine in New Zealand before returning to the UK to commence his specialist training in Respiratory Medicine. Having taken a break from training to undertake a PhD, Phil completed his specialist training in Respiratory and General Medicine. He now works as a Consultant at the Royal Devon & Exeter hospital and is an Honorary Senior Clinical Lecturer in the University of Exeter Medical School. His main areas of interest focus on chronic lung infections, particularly within the setting of bronchiectasis and cystic fibrosis.

Qualifications

  • MRCP (Resp Med) (Joint Royal Colleges of Physicians Training Board, 2020)
  • PhD (University of Exeter, 2018)
  • SCE, Respiratory Medicine (Royal College of Physicians, 2014)
  • MRCP (Royal College of Physicians, 2009)
  • MBBS (University College London, 2005)
  • BSc (University College London, 2002)

Research group links

Research

Research interests

After commencing specialty training in Respiratory Medicine, Phil developed a clinical interest in Cystic Fibrosis and Bronchiectasis. This expanded to a research interest as he undertook a PhD using molecular microbiological techniques to investigate bacteria in the lungs of these patients. This included investigating for cross-infection by a notorious bacteria via sequencing techniques and assessing microbial communities in the context of clinical disease. Phil continues to research these conditions with a focus on infection and an increased focus on antimicrobial resistance. He has a grant to investigate the resistome in respiratory patients and has been part of the GW4 Crucible Cohort (Interdisciplinary Approaches to Tackling AMR).  Via the GW4 Crucible programme he has a further seed corn grant to look in to a novel antimicrobial approach in cystic fibrosis in collaboration with other early career researchers in Bath, Bristol and Cardiff.

Phil was a Co-investigator on a COVID-19 vaccine trial (Novavax) and is currently the local PI for NIHR BioResource – Rare Diseases Study (CF) and ASPEN study. He has contributed to the British Thoracic Society's advice on managing patients with bronchiectasis in the endemic phase of the COVID-19 pandemic and COVID vaccination guidance for healthcare professionals.

Research projects

- Precision Maggot Therapy Against Key Cystic Fibrosis Pathogens

- Impact of long-term azithromycin therapy on the resistome of patients and their partners

- Rapid profiling of the bacterial community in the bronchiectatic lung

- Haemophilus influenzae cross-infection in non-cystic fibrosis bronchiectasis

- Bronchiectasis Exacerbation Assessment of Treatment (BEAT)

- Citizen Phage Library

Research networks

College of Medicine and Health, Univeristy of Exeter

- Dr Chris Scotton

Biosciences, University of Exeter:

- Dr Alan Brown, Prof Ben Temperton, Dr Steve Michell and Dr Julie Fletcher

Royal Devon & Exeter Hospital:

- Dr Nick Withers, Dr Chris Sheldon, Dr Tom Burden and Prof Michael Gibbons

Torbay Hospital:

- Dr Louise Anning

MRC CCM, University of Exeter: 

- Prof Adilia Warris, Dr Peter Cook and Elliott Mahoney

Cardiff University

- Dr Rebecca Weiser

University of Bath:

- Dr Neil Brown and Dr Maisem Laabei

University of Bristol:

- Dr Jon Tyrell 

PRISM SW (Pulmonary Research Inter-Site Matrix South West)

Research grants

  • 2021 Torbay Medical Research Fund
    Bronchiectasis Exacerbation Assessment of Treatment (BEAT)
  • 2021 Exeter Research Capacity Fund
    Mechanistic evaluation of the impacts of hypertonic saline in COPD in the MucAct Randomised Controlled Trial
  • 2020 Northcott Devon Medical Foundation
    Analysis of the resistomes of long-term azithromycin users with chronic respiratory disease and their partners
  • 2020 GW4
    Precision Maggot Therapy Against Key Cystic Fibrosis Pathogens
  • 2014 Exeter Trustees/RD
    Genetic typing of Pseudomonas strains in non-CF Bronchiectasis

Publications

Key publications | Publications by category | Publications by year

Publications by category

Journal articles

Mitchelmore PJ, Withers NJ, Sheldon CD, Scotton CJ, Brown AR (2021). Culture-independent multilocus sequence typing of Pseudomonas aeruginosa for cross-infection screening. Diagnostic Microbiology and Infectious Disease, 100(1), 115315-115315.
Smith D, Du Rand I, Addy CL, Collyns T, Hart SP, Mitchelmore PJ, Rahman NM, Saggu R (2020). British Thoracic Society guideline for the use of long-term macrolides in adults with respiratory disease. Thorax, 75(5), 370-404. Author URL.
Smith D, Du Rand IA, Addy C, Collyns T, Hart S, Mitchelmore P, Rahman N, Saggu R (2020). British Thoracic Society guideline for the use of long-term macrolides in adults with respiratory disease. BMJ Open Respir Res, 7(1). Abstract.  Author URL.
Mitchelmore P, Wilson C, Hettle D (2018). Risk of Bacterial Transmission in Bronchiectasis Outpatient Clinics. Current Pulmonology Reports, 7(3), 72-78.
Mitchelmore PJ, Randall J, Bull MJ, Moore KA, O'Neill PA, Paszkiewicz K, Mahenthiralingam E, Scotton CJ, Sheldon CD, Withers NJ, et al (2017). Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. Thorax Abstract.  Author URL.
Hopkinson N, Wallis C, Higgins B, Gaduzo S, Sherrington R, Keilty S, Stern M, Britton J, Bush A, Moxham J, et al (2013). Children must be protected from the tobacco industry's marketing tactics. BMJ, 347 Author URL.

Chapters

Mitchelmore P, Shrimanker R (2012). Chapter 2- Respiratory. In  (Ed) Succeeding in your Medical School Finals Instant revision notes, BPP Learning Media. Abstract.

Conferences

Wilson C, Mitchelmore P, Brown A (In Press). Culture-independent Multilocus Sequence Typing (MLST) screening for Haemophilus influenzae cross-infection in non-cystic fibrosis bronchiectasis (NCFB).
Mitchelmore P, Polverino E, Rademacher J, Haworth C, De Soyza A, Shteinburg M, Shoemark A, Altenburg J, Chalmers JD, Dimakou K, et al (2020). Immunodeficiency associated bronchiectasis in the European Bronchiectasis Registry (EMBARC). ERS International Congress 2020 abstracts.
Masey C, Hansell K, Mitchelmore P (2019). Comparison of pulmonary rehabilitation outcomes for different conditions and disease severities. ERS International Congress 2019 abstracts.
Wilson C, Mitchelmore P, Dunning H, Burden T (2019). P206 Attitudes towards treating latent tuberculosis in healthcare workers. British Thoracic Society Winter Meeting 2019, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 4 to 6 December 2019, Programme and Abstracts.
Dipper A, Morrison H, Jones R, Mitchelmore P, Welch H, Miller R, Bhatnagar R, Corcoran J, Gibbons M, Fallon J, et al (2019). We are not an island - initiating a respiratory trainee research network. ERS International Congress 2019 abstracts.
Mitchelmore P, Prior K, Martin S, Hughes R, Dawson M, Jones S, Crossingham G, Racey D, Laing J, Graham E, et al (2018). OUTCOMES AND PATIENT SATISFACTION FROM AN ESTABLISHED VIRTUAL PULMONARY NODULE CLINIC.  Author URL.
Mitchelmore P, Brown A, Sheldon C, Scotton C, Bull M, Mahenthiralingam E, Withers N (2015). AN EPIDEMIOLOGICAL REVIEW OF STRAINS OF PSEUDOMONAS AERUGINOSA IN a NON-CYSTIC FIBROSIS BRONCHIECTASIS COHORT.  Author URL.
Mitchelmore P, Anning L, Carnell V, Jephcote S, Charters P, Crowe T, Ean CD, Lowdon A, Sheldon C, Withers N, et al (2015). Azithromycin therapy and pseudomonas aeruginosa isolation in a non-cystic fibrosis bronchiectasis cohort.  Author URL.
Hynes G, Bakere H, McAleer C, Mitchelmore P, Hilton M, Halpin D (2015). The Benefits of an Integrated Vocal Cord Dysfunction Service in Treating a Subgroup of Patients with Difficult to Control Asthma.  Author URL.
Mitchelmore P, Hynes G, Jagger O, Lawson C, Carmichael C, Jeffery Z, Anning L, Bostock F, Patel B (2014). The Impact of a Higher Threshold for Elevated D-Dimer in Identifying Pulmonary Embolism in Patients with Possible Pneumonia.  Author URL.
Anning L, Carmichael C, Mitchelmore P, Teo B, Withers N (2014). Vitamin D levels in patiens with non-CF bronchiectasis.  Author URL.
Mitchelmore P, Sharp C, Unsworth R, Anning L, Burden T, Withers N (2013). EPIDEMIOLOGY, CHARACTERISTICS AND MANAGEMENT OF NON TUBERCULOUS MYCOBACTERIA IN a DEVON POPULATION.  Author URL.
Mitchelmore P, Sheldon C, Withers N (2013). OUTPATIENT SURVEY OF PATIENT EXPERIENCE OF HYPERTONIC SALINE USE IN NON-CYSTIC FIBROSIS BRONCHIECTASIS.  Author URL.
Hameed M, Sharp C, Mitchelmore P (2013). Self-assessed experience, competence and knowledge of non-invasive ventilation amongst medical trainees.  Author URL.
Mitchelmore P, Shrimanker R, McClue G, Pepperell J (2012). Can controlled oxygen be safely given in the home environment?.

Publications by year

In Press

Wilson C, Mitchelmore P, Brown A (In Press). Culture-independent Multilocus Sequence Typing (MLST) screening for Haemophilus influenzae cross-infection in non-cystic fibrosis bronchiectasis (NCFB).

2021

Mitchelmore PJ, Withers NJ, Sheldon CD, Scotton CJ, Brown AR (2021). Culture-independent multilocus sequence typing of Pseudomonas aeruginosa for cross-infection screening. Diagnostic Microbiology and Infectious Disease, 100(1), 115315-115315.

2020

Smith D, Du Rand I, Addy CL, Collyns T, Hart SP, Mitchelmore PJ, Rahman NM, Saggu R (2020). British Thoracic Society guideline for the use of long-term macrolides in adults with respiratory disease. Thorax, 75(5), 370-404. Author URL.
Smith D, Du Rand IA, Addy C, Collyns T, Hart S, Mitchelmore P, Rahman N, Saggu R (2020). British Thoracic Society guideline for the use of long-term macrolides in adults with respiratory disease. BMJ Open Respir Res, 7(1). Abstract.  Author URL.
Mitchelmore P, Polverino E, Rademacher J, Haworth C, De Soyza A, Shteinburg M, Shoemark A, Altenburg J, Chalmers JD, Dimakou K, et al (2020). Immunodeficiency associated bronchiectasis in the European Bronchiectasis Registry (EMBARC). ERS International Congress 2020 abstracts.

2019

Masey C, Hansell K, Mitchelmore P (2019). Comparison of pulmonary rehabilitation outcomes for different conditions and disease severities. ERS International Congress 2019 abstracts.
Wilson C, Mitchelmore P, Dunning H, Burden T (2019). P206 Attitudes towards treating latent tuberculosis in healthcare workers. British Thoracic Society Winter Meeting 2019, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 4 to 6 December 2019, Programme and Abstracts.
Dipper A, Morrison H, Jones R, Mitchelmore P, Welch H, Miller R, Bhatnagar R, Corcoran J, Gibbons M, Fallon J, et al (2019). We are not an island - initiating a respiratory trainee research network. ERS International Congress 2019 abstracts.

2018

Mitchelmore P, Prior K, Martin S, Hughes R, Dawson M, Jones S, Crossingham G, Racey D, Laing J, Graham E, et al (2018). OUTCOMES AND PATIENT SATISFACTION FROM AN ESTABLISHED VIRTUAL PULMONARY NODULE CLINIC.  Author URL.
Mitchelmore P, Wilson C, Hettle D (2018). Risk of Bacterial Transmission in Bronchiectasis Outpatient Clinics. Current Pulmonology Reports, 7(3), 72-78.

2017

Mitchelmore PJ, Randall J, Bull MJ, Moore KA, O'Neill PA, Paszkiewicz K, Mahenthiralingam E, Scotton CJ, Sheldon CD, Withers NJ, et al (2017). Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. Thorax Abstract.  Author URL.

2015

Mitchelmore P, Brown A, Sheldon C, Scotton C, Bull M, Mahenthiralingam E, Withers N (2015). AN EPIDEMIOLOGICAL REVIEW OF STRAINS OF PSEUDOMONAS AERUGINOSA IN a NON-CYSTIC FIBROSIS BRONCHIECTASIS COHORT.  Author URL.
Mitchelmore P, Anning L, Carnell V, Jephcote S, Charters P, Crowe T, Ean CD, Lowdon A, Sheldon C, Withers N, et al (2015). Azithromycin therapy and pseudomonas aeruginosa isolation in a non-cystic fibrosis bronchiectasis cohort.  Author URL.
Hynes G, Bakere H, McAleer C, Mitchelmore P, Hilton M, Halpin D (2015). The Benefits of an Integrated Vocal Cord Dysfunction Service in Treating a Subgroup of Patients with Difficult to Control Asthma.  Author URL.

2014

Mitchelmore P, Hynes G, Jagger O, Lawson C, Carmichael C, Jeffery Z, Anning L, Bostock F, Patel B (2014). The Impact of a Higher Threshold for Elevated D-Dimer in Identifying Pulmonary Embolism in Patients with Possible Pneumonia.  Author URL.
Anning L, Carmichael C, Mitchelmore P, Teo B, Withers N (2014). Vitamin D levels in patiens with non-CF bronchiectasis.  Author URL.

2013

Hopkinson N, Wallis C, Higgins B, Gaduzo S, Sherrington R, Keilty S, Stern M, Britton J, Bush A, Moxham J, et al (2013). Children must be protected from the tobacco industry's marketing tactics. BMJ, 347 Author URL.
Mitchelmore P, Sharp C, Unsworth R, Anning L, Burden T, Withers N (2013). EPIDEMIOLOGY, CHARACTERISTICS AND MANAGEMENT OF NON TUBERCULOUS MYCOBACTERIA IN a DEVON POPULATION.  Author URL.
Mitchelmore P, Sheldon C, Withers N (2013). OUTPATIENT SURVEY OF PATIENT EXPERIENCE OF HYPERTONIC SALINE USE IN NON-CYSTIC FIBROSIS BRONCHIECTASIS.  Author URL.
Hameed M, Sharp C, Mitchelmore P (2013). Self-assessed experience, competence and knowledge of non-invasive ventilation amongst medical trainees.  Author URL.

2012

Mitchelmore P, Shrimanker R, McClue G, Pepperell J (2012). Can controlled oxygen be safely given in the home environment?.
Mitchelmore P, Shrimanker R (2012). Chapter 2- Respiratory. In  (Ed) Succeeding in your Medical School Finals Instant revision notes, BPP Learning Media. Abstract.

Philip_MItchelmore Details from cache as at 2022-10-07 12:56:00

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External Engagement and Impact

Committee/panel activities

Current

  • Inaugural Co-chair and current Consultant Lead for PRISM South West (Pulmonary Research Inter-Site Matrix)
  • Phage-UK Clinical Group

Past

  • Member of the Specialist Advisory Group for Pulmonary Infection (British Thoracic Society)
  • Member of the guideline group for long-term macrolide use (British Thoracic Society)
  • Working group for Hospital-acquired pneumonia (Public Health England)

Evidence of impact on policy and professional practice

British Thoracic Society Documents

- BTS Guidance: COVID-19 Vaccination – information for health care professionals

- British Thoracic Society Advice for Managing Patients with Bronchiectasis in the endemic phase of the COVID-19 pandemic

- British Thoracic Society guideline for the use of long-term macrolides in adults with respiratory disease


Invited lectures

  • “Characterisation and management of the lung microbiome in Bronchiectasis”- Exeter Expert Series- Respiratory (Practical Genomics with a Clinical Perspective)
  • Delivered Bronchiectasis Training days to South-West Trainees
  • "Setting up a respiratory trainee network in the South-West"- NIHR CRSL Annual Summit (Peninsula)

Teaching

Phil provides clinical teaching to undergraduate medical students within the Royal Devon & Exeter Hospital setting

Supervision / Group

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