COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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Mr Paul Weightman Potter BSc

PhD student

 01392 408269

 RILD Building Level 4

 

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Overview

I completed my undergraduate degree in biology at the University of Bath where I also had a professional placement year at the Peninsula Colleges of Medicine and Dentistry. Here I worked under Dr. Oleg Anichtchik focussing on an in vitro model of alpha-synuclein’s interactions with tau protein to model aspects of neurodegeneration. I returned to the University of Bath and graduated in 2015 with a 1st class BSc (Hons). Since then, I have been working under the supervision of Dr Craig Beall investigating how glucose variation seen in type 1 diabetes impacts neural cells, and how that might increase the risk of dementia. My research interests include brain energy metabolism and the interplay between glia and neurons in physiological and pathological states.

Qualifications

  • 2015: 1st class BSc (Hons) Biology with professional placement

Research

Research interests

Since September 2015 I have been a PhD student in Dr Craig Beall’s research group, co-supervised by Prof Andrew Randall. My PhD project focusses on the impact of glucose variability on neural signalling in human brain cells and how that relates to dementia risk. My particular research interests focus on brain energy metabolism and the interplay between glia and neurons in both physiological and pathological states.

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Vlachaki Walker JM, Robb JL, Cruz AM, Malhi A, Weightman Potter PG, Ashford ML, McCrimmon RJ, Ellacott KL, Beall C (In Press). AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner. Diabetes, Obesity and Metabolism Full text.
Weightman Potter P, Vlachaki Walker J, Robb J, Chilton J, Williamson R, Randall A, Ellacott K, Beall C (In Press). Basal fatty acid oxidation increases after recurrent low glucose in human primary astrocytes. Diabetologia Full text.
Cruz AM, Malekizadeh Y, Vlachaki Walker JM, Weightman Potter PG, Pye K, Shaw SJ, Ellacott KLJ, Beall C (In Press). Brain permeable AMPK activator R481 raises glycemia by autonomic nervous system activation and amplifies the counterregulatory response to hypoglycemia in rats.  Abstract.
Weightman Potter PG, Walker JMV, Robb JL, Chilton JK, Williamson R, Randall A, Ellacott KLJ, Beall C (In Press). Human primary astrocytes increase basal fatty acid oxidation following recurrent low glucose to maintain intracellular nucleotide levels.  Abstract.
Robb JL, Morrissey NA, Weightman Potter PG, Smithers HE, Beall C, Ellacott KLJ (2019). Immunometabolic Changes in Glia – a Potential Role in the Pathophysiology of Obesity and Diabetes. Neuroscience Full text.
(2017). Basic and clinical science posters: brain function. Diabetic Medicine, 34, 48-49.

Publications by year


In Press

Vlachaki Walker JM, Robb JL, Cruz AM, Malhi A, Weightman Potter PG, Ashford ML, McCrimmon RJ, Ellacott KL, Beall C (In Press). AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner. Diabetes, Obesity and Metabolism Full text.
Weightman Potter P, Vlachaki Walker J, Robb J, Chilton J, Williamson R, Randall A, Ellacott K, Beall C (In Press). Basal fatty acid oxidation increases after recurrent low glucose in human primary astrocytes. Diabetologia Full text.
Cruz AM, Malekizadeh Y, Vlachaki Walker JM, Weightman Potter PG, Pye K, Shaw SJ, Ellacott KLJ, Beall C (In Press). Brain permeable AMPK activator R481 raises glycemia by autonomic nervous system activation and amplifies the counterregulatory response to hypoglycemia in rats.  Abstract.
Weightman Potter PG, Walker JMV, Robb JL, Chilton JK, Williamson R, Randall A, Ellacott KLJ, Beall C (In Press). Human primary astrocytes increase basal fatty acid oxidation following recurrent low glucose to maintain intracellular nucleotide levels.  Abstract.

2019

Robb JL, Morrissey NA, Weightman Potter PG, Smithers HE, Beall C, Ellacott KLJ (2019). Immunometabolic Changes in Glia – a Potential Role in the Pathophysiology of Obesity and Diabetes. Neuroscience Full text.
Weightman Potter P (2019). The impact of glucose variation on human astrocytes.  Abstract.  Full text.

2017

(2017). Basic and clinical science posters: brain function. Diabetic Medicine, 34, 48-49.

Paul_Weightmanpotter Details from cache as at 2020-01-26 14:37:39

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