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Dr Paul Weightman Potter BSc, PhD

Postdoctoral Research Associate

 01392 408213

 RILD Building Level 4

 

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Overview

I am a postdoctoral research associate working at Dr Craig Beall's lab. My research interests include brain energy metabolism and the interplay between glia and neurons in physiological and pathological states, particularly in type 1 diabetes. My current projects investigates the role of altered astrocytic metabolism on glutamate handling in the context of recurrent hypoglycaemia. I previously completed my PhD under Dr Craig Beall's supervision in 2019, working on the impact of glucose variation on human astrocytes.

Previously, I completed my undergraduate degree in biology at the University of Bath where I also had a professional placement year at the Peninsula Colleges of Medicine and Dentistry. Here I worked under Dr. Oleg Anichtchik focussing on an in vitro model of alpha-synuclein’s interactions with tau protein to model aspects of neurodegeneration. I returned to the University of Bath and graduated in 2015 with a 1st class BSc (Hons).

Qualifications

  • 2019: PhD in Medical Studies - "The Impact of Glucose Variation on Human Astrocytes"
  • 2015: 1st class BSc (Hons) Biology with professional placement

Research

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Vlachaki Walker JM, Robb JL, Cruz AM, Malhi A, Weightman Potter PG, Ashford ML, McCrimmon RJ, Ellacott KL, Beall C (In Press). AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner. Diabetes, Obesity and Metabolism Full text.
Potter PGW, Washer S, Jeffries AR, Holley JE, Gutowski NJ, Dempster E, Beall C (In Press). Analysis of the transcriptome and DNA methylome in response to acute and recurrent low glucose in human primary astrocytes.  Abstract.
Weightman Potter P, Vlachaki Walker J, Robb J, Chilton J, Williamson R, Randall A, Ellacott K, Beall C (In Press). Basal fatty acid oxidation increases after recurrent low glucose in human primary astrocytes. Diabetologia Full text.
Cruz AM, Malekizadeh Y, Vlachaki Walker JM, Weightman Potter PG, Pye K, Shaw SJ, Ellacott KLJ, Beall C (In Press). Brain permeable AMPK activator R481 raises glycemia by autonomic nervous system activation and amplifies the counterregulatory response to hypoglycemia in rats.  Abstract.
Weightman Potter PG, Walker JMV, Robb JL, Chilton JK, Williamson R, Randall A, Ellacott KLJ, Beall C (In Press). Human primary astrocytes increase basal fatty acid oxidation following recurrent low glucose to maintain intracellular nucleotide levels.  Abstract.
Robb JL, Morrissey NA, Weightman Potter PG, Smithers HE, Beall C, Ellacott KLJ (2020). Immunometabolic Changes in Glia – a Potential Role in the Pathophysiology of Obesity and Diabetes. Neuroscience, 447, 167-181. Full text.
Robb JL, Hammad NA, Weightman Potter PG, Chilton JK, Beall C, Ellacott KLJ (2020). The metabolic response to inflammation in astrocytes is regulated by nuclear factor‐kappa B signaling. Glia, 68(11), 2246-2263. Full text.
(2017). Basic and clinical science posters: brain function. Diabetic Medicine, 34, 48-49.

Publications by year


In Press

Vlachaki Walker JM, Robb JL, Cruz AM, Malhi A, Weightman Potter PG, Ashford ML, McCrimmon RJ, Ellacott KL, Beall C (In Press). AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner. Diabetes, Obesity and Metabolism Full text.
Potter PGW, Washer S, Jeffries AR, Holley JE, Gutowski NJ, Dempster E, Beall C (In Press). Analysis of the transcriptome and DNA methylome in response to acute and recurrent low glucose in human primary astrocytes.  Abstract.
Weightman Potter P, Vlachaki Walker J, Robb J, Chilton J, Williamson R, Randall A, Ellacott K, Beall C (In Press). Basal fatty acid oxidation increases after recurrent low glucose in human primary astrocytes. Diabetologia Full text.
Cruz AM, Malekizadeh Y, Vlachaki Walker JM, Weightman Potter PG, Pye K, Shaw SJ, Ellacott KLJ, Beall C (In Press). Brain permeable AMPK activator R481 raises glycemia by autonomic nervous system activation and amplifies the counterregulatory response to hypoglycemia in rats.  Abstract.
Weightman Potter PG, Walker JMV, Robb JL, Chilton JK, Williamson R, Randall A, Ellacott KLJ, Beall C (In Press). Human primary astrocytes increase basal fatty acid oxidation following recurrent low glucose to maintain intracellular nucleotide levels.  Abstract.

2020

Robb JL, Morrissey NA, Weightman Potter PG, Smithers HE, Beall C, Ellacott KLJ (2020). Immunometabolic Changes in Glia – a Potential Role in the Pathophysiology of Obesity and Diabetes. Neuroscience, 447, 167-181. Full text.
Robb JL, Hammad NA, Weightman Potter PG, Chilton JK, Beall C, Ellacott KLJ (2020). The metabolic response to inflammation in astrocytes is regulated by nuclear factor‐kappa B signaling. Glia, 68(11), 2246-2263. Full text.

2019

Weightman Potter P (2019). The impact of glucose variation on human astrocytes.  Abstract.  Full text.

2017

(2017). Basic and clinical science posters: brain function. Diabetic Medicine, 34, 48-49.

Paul_Weightmanpotter Details from cache as at 2020-12-05 04:45:10

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