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Dr Luke Mounce

Dr Luke Mounce

Research Fellow

2900

South Cloisters 1.10

Luke is a Research Fellow working in the Health Statistics Research Group and the Health Services and Policy Research Group.  He has a background in Psychology and Research Methods, and has been lead quantitative analyst on NIHR funded programmes investigating the dynamics of quality of care, and on improving patient experience of Primary Care.

His main research interests include the determinants and impact of multimorbidity (having two or more chronic health conditions), the quality and safety of care provided in Primary Care, and the use of quasi-experimental approaches for reducing bias in observational datasets.

Broad Research Specialisms

Luke is continuing to develop skills to facilitate research across a range of fields:

  • Management of large observational datasets (e.g. CPRD, the English Longitudinal Study of Aging, and the General Practice Patient Survey)
  • Quamtitative modelling
  • Questionnaire development (including use of Classical Test Theory and Item Response Theory)
  • Use of the Prior Event Rate Ration (PERR) for addressing unmeasured confounders in observational datasets

Qualifications

BSc (hons) in Psychology (Exeter, UK)

MSc in Psychological Research Methods (Exeter, UK)

PhD in Psychology (focus: clinical neuropsychology) (Exeter, UK)

Graduate Certificate in Statistics (Sheffield, UK)

Research

Research interests

Luke is a methodologist and aims to be able to provide analytic support to projects covering a wide range of topics.  His particular interests include:

  • Longitudinal modelling of health outcomes
  • Latent variable modelling
  • Psychometrics and Item Response Theory
  • Management of large datasets
  • Qusasi-experimental approaches for reducing bias in observational data

Research projects

Luke is involved in projects covering a number of work-streams:

Pharmacovigilance and Patient Safety

  • Exploring differences in risk of side-effects (odeama, heart failure, weight gain) in second line pharmacotherapies for type II diabetes.  This work is funded by Quintiles, and uses data from the Clinical Practice Research Datalink, applying the Prior Event Rate Ratio to address unmeasured confounding (e.g. confounding by indication).
  • Exploring the suitability of treatment stratification of second line pharmacotherapies for type II diabetes, as part of the MASTERMIND programme.  This work uses both observational datasets and trial data.
  • Developing short-form versions of the Patient Reported Experiences and Outcomes of Safety in Primary Care (PREOS-PC) questionnaire.  PREOS-PC is a recently developed patient reported outcome measure (PROM) of experiences safety in Primary Care, consisting of 54 items and 11 scales.  This project is developing a compact version of the instrument, retaining the scales, but using a reduced number of items, as well as a short 6 item screening tool.  This process is being informed by use of both Classical Test Theory and Item Response Theory, and uses data collected for the development of the original measure.
  • An investigation of the impact of multimorbidity on patient safety, using the PREOS-PC questionnaire.

Determinants and Impact of Multimorbidity

  • An investigation into the socio-demographic and lifestyle determinants of multimorbidity (having two or more chronic conditions) in older people, using the English Longitudinal Study of Aging (ELSA).  This is a prospective cohort study, following participants over ten years.
  • An exploration of common patterns of multimorbidity, using tetrachoric factor analysis to find the ways in which conditions tend to co-occur.
  • The determinants of clusters of multimorbidity.
  • The impact of multimorbidity on quality of care (individual level).  Using ELSA data and published quality indicators, we are exploring how the number of conditions, and the number of condition-clusters, affects subsequent quality of care for a number of common conditions in older people.
  • The impact of multimorbidity on quality of care (practice level). Using QOF/QMAS data from ~8000 General Practices in England, we are exploring the effect of additional conditions on the quality of care received for index condition (e.g. ischaemic heart disease, hypertension, mental health conditions).  In particular, we are testing the hypothesis that there will be little impact when additional conditions are 'concrodant', sharing a similar pathophysiologic risk profile (and therefore more likely to be part of the same management plan), relative to when additional conditions are 'discordant'.
  • The impact of multimorbidity on ease of cancer diagnosis.  Using CPRD, we are exploring how the presence of additional conditions affects the time taken to diagnose colorectal cancer after presentation of the first sign/symptom.

Key publications | Publications by category | Publications by year

Key publications


Mounce LTA, Price S, Valderas JM, Hamilton W (2017). Comorbid conditions delay diagnosis of colorectal cancer: a cohort study using electronic primary care records. Br J Cancer, 116(12), 1536-1543. Abstract.  Author URL.  Full text.
Steel N, Hardcastle AC, Bachmann MO, Richards SH, Mounce LTA, Clark A, Lang I, Melzer D, Campbell JL (2015). Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study. BMJ Open, 4(10). Abstract.  Full text.
Steel N, Hardcastle AC, Clark A, Mounce LTA, Bachmann MO, Richards SH, Henley WE, Campbell JL, Melzer D (2014). Self-reported quality of care for older adults from 2004 to 2011: a cohort study. Age Ageing, 43(5), 716-720. Abstract.  Author URL.  Full text.
Mounce LTA, Williams WH, Jones JM, Harris A, Haslam SA, Jetten J (2013). Neurogenic and psychogenic acute postconcussion symptoms can be identified after mild traumatic brain injury. J Head Trauma Rehabil, 28(5), 397-405. Abstract.  Author URL.
Davies RC, Williams WH, Hinder D, Burgess CN, Mounce LT (2012). Self-reported traumatic brain injury and postconcussion symptoms in incarcerated youth. J Head Trauma Rehabil, 27(3), E21-E27. Abstract.  Author URL.
Tonks J, Williams WH, Mounce L, Harris D, Frampton I, Yates P, Slater A (2011). 'Trails B or not Trails B?' is attention-switching a useful outcome measure?. Brain Inj, 25(10), 958-964. Abstract.  Author URL.

Publications by category


Journal articles

Mounce LTA, Williams WH, Harris A, Yates PJ, Llewellyn D (In Press). Deprivation increases risk of head versus orthopaedic injury in children and young people.
Mounce LTA, Price S, Valderas JM, Hamilton W (2017). Comorbid conditions delay diagnosis of colorectal cancer: a cohort study using electronic primary care records. Br J Cancer, 116(12), 1536-1543. Abstract.  Author URL.  Full text.
Burt J, Campbell J, Abel G, Aboulghate A, Ahmed F, Asprey A, Barry H, Beckwith J, Benson J, Boiko O, et al (2017). Improving patient experience in primary care: a multimethod programme of research on the measurement and improvement of patient experience. Programme Grants for Applied Research, 5(9), 1-452. Full text.
Wright C, Davey A, Elmore N, Carter M, Mounce L, Wilson E, Burt J, Roland M, Campbell J (2017). Patients' use and views of real-time feedback technology in general practice. Health Expect, 20(3), 419-433. Abstract.  Author URL.  Full text.
Mounce LTA, Barry HE, Calitri R, Henley WE, Campbell J, Roland M, Richards S (2016). Establishing the validity of English GP Patient Survey items evaluating out-of-hours care. BMJ Qual Saf, 25(11), 842-850. Abstract.  Author URL.  Full text.
Davey AF, Roberts MJ, Mounce L, Maramba I, Campbell JL (2016). Test–retest stability of patient experience items derived from the national GP patient survey. SpringerPlus, 5(1). Abstract.  Full text.
Steel N, Hardcastle AC, Bachmann MO, Richards SH, Mounce LTA, Clark A, Lang I, Melzer D, Campbell JL (2015). Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study. BMJ Open, 4(10). Abstract.  Full text.
Ricci-Cabello I, Violán C, Foguet-Boreu Q, Mounce LTA, Valderas JM (2015). Impact of multi-morbidity on quality of healthcare and its implications for health policy, research and clinical practice. A scoping review. Eur J Gen Pract, 21(3), 192-202. Abstract.  Author URL.
Mounce LTA, Steel N, Hardcastle AC, Henley WE, Bachmann MO, Campbell JL, Melzer D, Richards SH (2015). Patient characteristics predicting failure to receive indicated care for type 2 diabetes. Diabetes Research and Clinical Practice, 107(2), 247-258. Abstract.  Full text.
Hardcastle AC, Mounce LTA, Richards SH, Bachmann MO, Clark A, Henley WE, Campbell JL, Melzer D, Steel N (2015). The dynamics of quality: a national panel study of evidence-based standards. Health Services and Delivery Research, 3(11), 1-128. Full text.
Hughes N, Williams WH, Chitsabesan P, Walesby RC, Mounce LTA, Clasby B (2015). The prevalence of traumatic brain injury among young offenders in custody: a systematic review. J Head Trauma Rehabil, 30(2), 94-105. Abstract.  Author URL.
Steel N, Hardcastle AC, Clark A, Mounce LTA, Bachmann MO, Richards SH, Henley WE, Campbell JL, Melzer D (2014). Self-reported quality of care for older adults from 2004 to 2011: a cohort study. Age Ageing, 43(5), 716-720. Abstract.  Author URL.  Full text.
Hardcastle A, Mounce LT, Steel N (2013). HAS THE QUALITY OF CARE WORSENED FOR GERIATRIC CONDITIONS?. GERONTOLOGIST, 53, 204-204. Author URL.
Mounce LTA, Williams WH, Jones JM, Harris A, Haslam SA, Jetten J (2013). Neurogenic and psychogenic acute postconcussion symptoms can be identified after mild traumatic brain injury. J Head Trauma Rehabil, 28(5), 397-405. Abstract.  Author URL.
Hardcastle A, Mounce LT, Steel N (2013). WHAT PREDICTS QUALITY OF CARE: RESULTS FROM THE ENGLISH LONGITUDINAL STUDY OF AGEING. GERONTOLOGIST, 53, 205-205. Author URL.
Mounce L, Williams H (2012). Outcome following Mild Traumatic Brain Injury: the interplay of concussion and post-traumatic stress. BRAIN INJURY, 26(4-5), 638-639. Author URL.
Davies RC, Williams WH, Hinder D, Burgess CN, Mounce LT (2012). Self-reported traumatic brain injury and postconcussion symptoms in incarcerated youth. J Head Trauma Rehabil, 27(3), E21-E27. Abstract.  Author URL.
Tonks J, Williams WH, Mounce L, Harris D, Frampton I, Yates P, Slater A (2011). 'Trails B or not Trails B?' is attention-switching a useful outcome measure?. Brain Inj, 25(10), 958-964. Abstract.  Author URL.

Conferences

Mounce LTA (2014). Do Patient’s Characteristics Predict Failure to Receive Care for Type 2 Diabetes?. Society for Academic Primary Care (regional). 6th - 7th Mar 2014.
Mounce LTA (2014). Do Patient’s Characteristics Predict Failure to Receive Care for Type 2 Diabetes?. Society for Academic Primary Care. 9th - 11th Jul 2014. Abstract.
Hardcastle AC, Mounce LTA, Steel N (2014). What predicts quality of care: results from the English Longitudinal Study of Ageing. Gerontological Society of America 66th annual scientific meeting. 14th - 18th Nov 2014.
Hardcastle AC, Mounce LTA, Steel N (2014). What predicts quality of care: results from the English Longitudinal Study of Ageing. Gerontological Society of America 66th annual scientific meeting. 14th - 18th Nov 2014.
Mounce LTA (2012). Outcome following mild traumatic brain injury: the interplay of concussion and post-traumatic stress. 9th World Congress on Brain Injury. 22nd - 25th Mar 2012.
Mounce LTA, Williams WH (2011). The Neurological and Psychological Roots of Post-Concussion Syndrome After MTBI: the Role of Traumatic Re-Experiencing. 4th Pacific Rim Meeting. 6th - 9th Jul 2011.
Mounce LTA, Williams WH (2010). Does acute stress predict mTBI symptoms?. Annual Meeting of Emergency Medicine. 22nd - 25th Mar 2010.
Mounce LTA (2007). Risk of psychiatric disorder in children with congenital versus acquired brain-dysfunction. 4th Satellite Symposium on Neuropsychological Rehabilitation. 9th - 11th Jul 2007.

Reports

Melzer D, Tavakoly B, Winder R, Richards S, Mounce LTA, Gericke C, Lang I (2012). Health Care Quality for an Active Later Life: Improving quality of prevention and treatment through information - England 2005 to 2012. A report from the Peninsula College of Medicine and Dentistry Ageing Research Group for Age UK.

Publications by year


In Press

Mounce LTA, Williams WH, Harris A, Yates PJ, Llewellyn D (In Press). Deprivation increases risk of head versus orthopaedic injury in children and young people.

2017

Mounce LTA, Price S, Valderas JM, Hamilton W (2017). Comorbid conditions delay diagnosis of colorectal cancer: a cohort study using electronic primary care records. Br J Cancer, 116(12), 1536-1543. Abstract.  Author URL.  Full text.
Burt J, Campbell J, Abel G, Aboulghate A, Ahmed F, Asprey A, Barry H, Beckwith J, Benson J, Boiko O, et al (2017). Improving patient experience in primary care: a multimethod programme of research on the measurement and improvement of patient experience. Programme Grants for Applied Research, 5(9), 1-452. Full text.
Wright C, Davey A, Elmore N, Carter M, Mounce L, Wilson E, Burt J, Roland M, Campbell J (2017). Patients' use and views of real-time feedback technology in general practice. Health Expect, 20(3), 419-433. Abstract.  Author URL.  Full text.

2016

Mounce LTA, Barry HE, Calitri R, Henley WE, Campbell J, Roland M, Richards S (2016). Establishing the validity of English GP Patient Survey items evaluating out-of-hours care. BMJ Qual Saf, 25(11), 842-850. Abstract.  Author URL.  Full text.
Davey AF, Roberts MJ, Mounce L, Maramba I, Campbell JL (2016). Test–retest stability of patient experience items derived from the national GP patient survey. SpringerPlus, 5(1). Abstract.  Full text.

2015

Steel N, Hardcastle AC, Bachmann MO, Richards SH, Mounce LTA, Clark A, Lang I, Melzer D, Campbell JL (2015). Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study. BMJ Open, 4(10). Abstract.  Full text.
Ricci-Cabello I, Violán C, Foguet-Boreu Q, Mounce LTA, Valderas JM (2015). Impact of multi-morbidity on quality of healthcare and its implications for health policy, research and clinical practice. A scoping review. Eur J Gen Pract, 21(3), 192-202. Abstract.  Author URL.
Mounce LTA, Steel N, Hardcastle AC, Henley WE, Bachmann MO, Campbell JL, Melzer D, Richards SH (2015). Patient characteristics predicting failure to receive indicated care for type 2 diabetes. Diabetes Research and Clinical Practice, 107(2), 247-258. Abstract.  Full text.
Hardcastle AC, Mounce LTA, Richards SH, Bachmann MO, Clark A, Henley WE, Campbell JL, Melzer D, Steel N (2015). The dynamics of quality: a national panel study of evidence-based standards. Health Services and Delivery Research, 3(11), 1-128. Full text.
Hughes N, Williams WH, Chitsabesan P, Walesby RC, Mounce LTA, Clasby B (2015). The prevalence of traumatic brain injury among young offenders in custody: a systematic review. J Head Trauma Rehabil, 30(2), 94-105. Abstract.  Author URL.

2014

Mounce LTA (2014). Do Patient’s Characteristics Predict Failure to Receive Care for Type 2 Diabetes?. Society for Academic Primary Care (regional). 6th - 7th Mar 2014.
Mounce LTA (2014). Do Patient’s Characteristics Predict Failure to Receive Care for Type 2 Diabetes?. Society for Academic Primary Care. 9th - 11th Jul 2014. Abstract.
Steel N, Hardcastle AC, Clark A, Mounce LTA, Bachmann MO, Richards SH, Henley WE, Campbell JL, Melzer D (2014). Self-reported quality of care for older adults from 2004 to 2011: a cohort study. Age Ageing, 43(5), 716-720. Abstract.  Author URL.  Full text.
Hardcastle AC, Mounce LTA, Steel N (2014). What predicts quality of care: results from the English Longitudinal Study of Ageing. Gerontological Society of America 66th annual scientific meeting. 14th - 18th Nov 2014.
Hardcastle AC, Mounce LTA, Steel N (2014). What predicts quality of care: results from the English Longitudinal Study of Ageing. Gerontological Society of America 66th annual scientific meeting. 14th - 18th Nov 2014.

2013

Hardcastle A, Mounce LT, Steel N (2013). HAS THE QUALITY OF CARE WORSENED FOR GERIATRIC CONDITIONS?. GERONTOLOGIST, 53, 204-204. Author URL.
Mounce LTA, Williams WH, Jones JM, Harris A, Haslam SA, Jetten J (2013). Neurogenic and psychogenic acute postconcussion symptoms can be identified after mild traumatic brain injury. J Head Trauma Rehabil, 28(5), 397-405. Abstract.  Author URL.
Hardcastle A, Mounce LT, Steel N (2013). WHAT PREDICTS QUALITY OF CARE: RESULTS FROM THE ENGLISH LONGITUDINAL STUDY OF AGEING. GERONTOLOGIST, 53, 205-205. Author URL.

2012

Melzer D, Tavakoly B, Winder R, Richards S, Mounce LTA, Gericke C, Lang I (2012). Health Care Quality for an Active Later Life: Improving quality of prevention and treatment through information - England 2005 to 2012. A report from the Peninsula College of Medicine and Dentistry Ageing Research Group for Age UK.
Mounce L, Williams H (2012). Outcome following Mild Traumatic Brain Injury: the interplay of concussion and post-traumatic stress. BRAIN INJURY, 26(4-5), 638-639. Author URL.
Mounce LTA (2012). Outcome following mild traumatic brain injury: the interplay of concussion and post-traumatic stress. 9th World Congress on Brain Injury. 22nd - 25th Mar 2012.
Davies RC, Williams WH, Hinder D, Burgess CN, Mounce LT (2012). Self-reported traumatic brain injury and postconcussion symptoms in incarcerated youth. J Head Trauma Rehabil, 27(3), E21-E27. Abstract.  Author URL.

2011

Tonks J, Williams WH, Mounce L, Harris D, Frampton I, Yates P, Slater A (2011). 'Trails B or not Trails B?' is attention-switching a useful outcome measure?. Brain Inj, 25(10), 958-964. Abstract.  Author URL.
Mounce LTA, Williams WH (2011). The Neurological and Psychological Roots of Post-Concussion Syndrome After MTBI: the Role of Traumatic Re-Experiencing. 4th Pacific Rim Meeting. 6th - 9th Jul 2011.

2010

Mounce LTA, Williams WH (2010). Does acute stress predict mTBI symptoms?. Annual Meeting of Emergency Medicine. 22nd - 25th Mar 2010.

2007

Mounce LTA (2007). Risk of psychiatric disorder in children with congenital versus acquired brain-dysfunction. 4th Satellite Symposium on Neuropsychological Rehabilitation. 9th - 11th Jul 2007.

During his PhD in psychology, Dr. Mounce had a post as an associate teaching fellow and taught on a wide range of modules in psychology, particularly advanced statistics.

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