COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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Professor Louise Allan

Professor Louise Allan

Professor of Geriatric Medicine

 01392 72 6025

 South Cloisters 1.39

 

South Cloisters, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK

Overview

Professor Louise Allan moved to the University of Exeter as Professor of Geriatric Medicine in June 2018. She has a specialist interest in the Neurology and Psychiatry of Old Age and is a member of the Centre for Research in Ageing and Cognitive Health (REACH), which is a joint venture between the School of Psychology, the University of Exeter Medical School and PenCLAHRC.

Current research themes focus on falls and physical health care in dementia, the effects of delirium upon cognitive decline, and non-Alzheimer’s dementias including post-stroke dementia and Lewy body disease.

Louise completed undergraduate studies at Oxford University and then did house jobs in Oxford and Whitehaven, after which she moved to Newcastle to complete higher medical training as a Geriatrician. She had an Alzheimer’s Society Fellowship for the completion of her doctoral studies on autonomic dysfunction in dementia and then she became a lecturer at Newcastle University (2007-2008) and subsequently a senior lecturer (2008-2018). Clinically, Louise will be working as a Geriatrician in the memory clinic at the Royal Devon and Exeter Hospital.

Qualifications

  • BA(Oxon)
  • MA (Oxon)
  • BMBCh
  • PhD (Newcastle)
  • MRCP (UK)

Research

Research interests

Louise’s research focusses on three themes: Physical health in dementia and Delirium, Vascular Cognitive Impairment and Lewy Body disease.

1.         Physical health in dementia

She has previously published work on the risk factors for falls in people with dementia, and is currently leading an NIHR funded Health Technology Assessment Programme to investigate whether it is possible to design a complex intervention to improve the outcome of fall related injuries in dementia (https://research.ncl.ac.uk/difrid/ ).

During her research into dementia delirium has emerged as a significant theme which needs further investigation. The DECIDE study is examining the role of delirium as a potential cause of and exacerbating factor for dementia in a  prospective study which we are now undertaking with the CFAS II cohort.

2.         Vascular Cognitive Impairment

This work includes the long term follow up of the MRC funded COGFAST cohort, one of the world’s largest and longest running clinicopathological cohort studies of people with cerebrovascular disease. We have reported on the long term incidence and neuropathological features of dementia and depression after stroke, and in particular identified that delayed dementia after stroke is primarily associated with predominantly vascular rather than mixed pathology.

We have also established a Nigerian cohort (COGFAST-Nigeria), which will enable comparisons of Vascular Cognitive Impairment between developed and developing countries, the latter being an increasingly important setting for dementia research due to the expanding and ageing demographics in the developing world.

3.         Lewy Body disease

The investigation of Lewy Body disorders is an important focus of research for the DEMANDS group and we host an NIHR Biomedical Research Unit in Lewy Body disease. She is a co-investigator in the DIAMOND-Lewy study, an NIHR funded programme grant which aims to improve the diagnosis and management of Lewy body disorders including Dementia with Lewy bodies and Parkinson’s disease dementia (https://research.ncl.ac.uk/diamondlewy/).

She has an interest in autonomic dysfunction in dementia, and previous work in the MRC funded Lewy Body Disease cohort study has shown that autonomic dysfunction is a particularly common feature of the Lewy body dementias and an important risk factor for falls.

Research projects

Grants/Funding:

  • Lawson R et al: Defining dELIRIUm and its iMpact in Parkinson’s Disease (DELIRIUM-PD) Supervisor, Parkinson’s UK Research Fellowship, £240,589 (2018-2021)
  • AL Robinson et al: Primary and community care based post diagnostic Dementia care (PriDem) Co-investigator Alzheimer’s Society Programme Grant £457,331.29 (2018-2019).
  • LM Allan et al: Identifying delirium in people with Parkinson’s disease (DETERMINE-PD) Principal Investigator Parkinson’s UK Project £29,926.88 (2017-1018).
  • Michael Sykes et al: NIHR Doctoral Fellowship –Supervisor: Enhancing audit and feedback in acute Trust dementia care. £341,011.78 (2017-2020).
  • LM Allan et al: Is it possible to develop a complex intervention to improve the outcome of fall-related injuries in people with dementia? Principal Investigator NIHR HTA Project 13/78/02 £513,008, (2015-2017).
  • S Richardson, LM Allan, S Parker: DECIDE: Delirium and Cognitive Impact in Dementia, Principal Supervisor, Alzheimer’s Society Research Fellowship, £217,232, (2015-2018).
  • A Thomas et al: 123I-MIBG Scintigraphy Utility as a biomarker for Prodromal DEmentia with Lewy Bodies (SUPErB) Co-investigator Alzheimer’s Research UK, £492,273, awarded 2015.
  • John O'Brien et al: Improving the Diagnosis and Management of Dementias of Lewy Body Type in the NHS (DIAMOND-Lewy) Co-investigator NIHR Programme grant, £1,195,337, (2013-2018).

 

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Robalino S, Nyakang'o SB, Beyer FR, Fox C, Allan LM (In Press). Effectiveness of interventions aimed at improving physical and psychological outcomes of fall-related injuries in people with dementia: a narrative systematic review. Syst Rev, 7(1). Abstract.  Author URL.
Kane JPM, Surendranathan A, Bentley A, Barker SAH, Taylor J-P, Thomas AJ, Allan LM, McNally RJ, James PW, McKeith IG, et al (2018). Clinical prevalence of Lewy body dementia. ALZHEIMERS RESEARCH & THERAPY, 10 Author URL.
Bamford C, Wheatley A, Shaw C, Allan LM (2018). Equipping staff with the skills to maximise recovery of people with dementia after an injurious fall. Aging Ment Health, 1-9. Abstract.  Author URL.
Allan LM, Wheatley A, Flynn E, Smith A, Fox C, Howel D, Barber R, Homer TM, Robinson L, Parry SW, et al (2018). Is it feasible to deliver a complex intervention to improve the outcome of falls in people with dementia? a protocol for the DIFRID feasibility study. Pilot Feasibility Stud, 4 Abstract.  Author URL.
Goodwin V, Allan L (2018). Mrs Smith has no rehab potential”: Does rehabilitation have a role in the management of people with dementia. Age and Ageing Full text.
Connors MH, Quinto L, McKeith I, Brodaty H, Allan L, Bamford C, Thomas A, Taylor J-P, O'Brien JT (2018). Non-pharmacological interventions for Lewy body dementia: a systematic review. Psychol Med, 48(11), 1749-1758. Abstract.  Author URL.
Skrobot OA, Black SE, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, O'Brien J, Pantoni L, Pasquier F, et al (2018). Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study. ALZHEIMERS & DEMENTIA, 14(3), 280-292. Author URL.
Thomas AJ, Taylor JP, McKeith I, Bamford C, Burn D, Allan L, O'Brien J (2018). Revision of assessment toolkits for improving the diagnosis of Lewy body dementia: the DIAMOND Lewy study. Int J Geriatr Psychiatry, 33(10), 1293-1304. Author URL.
Barnfield S, Pitts AC, Kalaria R, Allan L, Tullo E (2017). "Is all the stuff about neurons necessary?" the development of lay summaries to disseminate findings from the Newcastle Cognitive Function after Stroke (COGFAST) study. Res Involv Engagem, 3 Abstract.  Author URL.
Thomas AJ, Taylor JP, McKeith I, Bamford C, Burn D, Allan L, O'Brien J (2017). Development of assessment toolkits for improving the diagnosis of the Lewy body dementias: feasibility study within the DIAMOND Lewy study. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 32(12), 1280-1304. Author URL.
Akinyemi RO, Allan LM, Oakley A, Kalaria RN (2017). Hippocampal Neurodegenerative Pathology in Post-stroke Dementia Compared to Other Dementias and Aging Controls. FRONTIERS IN NEUROSCIENCE, 11 Author URL.
Richardson SJ, Davis DHJ, Stephan B, Robinson L, Brayne C, Barnes L, Parker S, Allan LM (2017). Protocol for the Delirium and Cognitive Impact in Dementia (DECIDE) study: a nested prospective longitudinal cohort study. BMC GERIATRICS, 17 Author URL.
Sachdev PS, Lo JW, Crawford JD, Mellon L, Hickey A, Williams D, Bordet R, Mendyk A-M, Gelé P, Deplanque D, et al (2017). STROKOG (stroke and cognition consortium): an international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease. Alzheimers Dement (Amst), 7, 11-23. Abstract.  Author URL.
Skrobot OA, O'Brien J, Black S, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, Pantoni L, Pasquier F, et al (2017). The Vascular Impairment of Cognition Classification Consensus Study. ALZHEIMERS & DEMENTIA, 13(6), 624-633. Author URL.
Harrison SL, Tang EYH, Keage HAD, Taylor J-P, Allan L, Robinson L, Jagger C, Rockwood K, Stephan BCM (2016). A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 42(1-2), 69-79. Author URL.
Kane JPM, Richardson S, Allan L, Thomas A (2016). Diagnosing dementia. BRITISH JOURNAL OF HOSPITAL MEDICINE, 77(2), C22-C25. Author URL.
Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung'u MN, Foster V, Craggs LJL, Washida K, Okamoto Y, Thomas AJ, et al (2016). Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia. BRAIN, 139, 242-258. Author URL.
Dichgans M, Wardlaw J, Smith E, Zietemann V, Seshadri S, Sachdev P, Biessels GJ, Fazekas F, Benavente O, Pantoni L, et al (2016). METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: an initiative of the Joint Programme for Neurodegenerative Disease Research. ALZHEIMERS & DEMENTIA, 12(12), 1235-1249. Author URL.
Chen A, Oakley AE, Monteiro M, Tuomela K, Allan LM, Mukaetova-Ladinska EB, O'Brien JT, Kalaria RN (2016). Multiplex analyte assays to characterize different dementias: brain inflammatory cytokines in poststroke and other dementias. NEUROBIOLOGY OF AGING, 38, 56-67. Author URL.
Akinyemi RO, Firbank M, Ogbole GI, Allan LM, Owolabi MO, Akinyemi JO, Yusuf BP, Ogunseyinde O, Ogunniyi A, Kalaria RN, et al (2015). Medial temporal lobe atrophy, white matter hyperintensities and cognitive impairment among Nigerian African stroke survivors. BMC Res Notes, 8 Abstract.  Author URL.
Tullo ES, Lee RP, Robinson L, Allan L (2015). Why is dementia different? Medical students' views about deceiving people with dementia. AGING & MENTAL HEALTH, 19(8), 731-738. Author URL.
Mayne DJF, Allan L, Reynish E, MacLullich AMJ, Vardy ERLC (2014). Experience and opinions on post-graduate dementia training in the UK: a survey of selected consultant geriatricians. AGE AND AGEING, 43(2), 263-266. Author URL.
Gemmell E, Tam E, Allan L, Hall R, Khundakar A, Oakley AE, Thomas A, Deramecourt V, Kalaria RN (2014). Neuron Volumes in Hippocampal Subfields in Delayed Poststroke and Aging-Related Dementias. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 73(4), 305-311. Author URL.
Akinyemi RO, Allan L, Owolabi MO, Akinyemi JO, Ogbole G, Ajani A, Firbank M, Ogunniyi A, Kalaria RN (2014). Profile and determinants of vascular cognitive impairment in African stroke survivors: the CogFAST Nigeria Study. JOURNAL OF THE NEUROLOGICAL SCIENCES, 346(1-2), 241-249. Author URL.
Foster V, Oakley AE, Slade JY, Hall R, Polvikoski TM, Burke M, Thomas AJ, Khundakar A, Allan LM, Kalaria RN, et al (2014). Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias. BRAIN, 137, 2509-2521. Author URL.
Kuhn E, Du X, McGrath K, Coveney S, O'Regan N, Richardson S, Teodorczuk A, Allan L, Wilson D, Inouye SK, et al (2014). Validation of a Consensus Method for Identifying Delirium from Hospital Records. PLOS ONE, 9(11). Author URL.
Allan LM, Rowan EN, Thomas AJ, Polvikoski TM, O'Brien JT, Kalaria RN (2013). Long-term incidence of depression and predictors of depressive symptoms in older stroke survivors. BRITISH JOURNAL OF PSYCHIATRY, 203(6), 453-460. Author URL.
Gemmell E, Bosomworth H, Allan L, Hall R, Khundakar A, Oakley AE, Deramecourt V, Polvikoski TM, O'Brien JT, Kalaria RN, et al (2012). Hippocampal Neuronal Atrophy and Cognitive Function in Delayed Poststroke and Aging-Related Dementias. STROKE, 43(3), 808-+. Author URL.
Firbank MJ, Allan LM, Burton EJ, Barber R, O'Brien JT, Kalaria RN (2012). Neuroimaging predictors of death and dementia in a cohort of older stroke survivors. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 83(3), 263-267. Author URL.
Allan LM, Rowan EN, Firbank MJ, Thomas AJ, Parry SW, Polvikoski TM, O'Brien JT, Kalaria RN (2011). Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors. BRAIN, 134, 3713-3724. Author URL.
Morris CM, Ballard CG, Allan L, Rowan E, Stephens S, Firbank M, Ford GA, Kenny RA, O'Brien JT, Kalaria RN, et al (2011). NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors. Neurobiology of Aging, 32(3). Abstract.
Tullo E, Allan L (2011). What should we be teaching medical students about dementia?. INTERNATIONAL PSYCHOGERIATRICS, 23(7), 1044-1050. Author URL.
Tullo ES, Spencer J, Allan L (2010). Systematic Review: Helping the Young to Understand the Old. Teaching Interventions in Geriatrics to Improve the Knowledge, Skills, and Attitudes of Undergraduate Medical Students. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 58(10), 1987-1993. Author URL.
Miller VM, Kenny RA, Oakley AE, Hall R, Kalaria RN, Allan LM (2009). Dorsal Motor Nucleus of Vagus protein aggregates in Lewy Body Disease with autonomic dysfunction. BRAIN RESEARCH, 1286, 165-173. Author URL.
Allan LM, Ballard CG, Rowan EN, Kenny RA (2009). Incidence and prediction of falls in dementia: a prospective study in older people. PLoS ONE, 4(5). Abstract.
Allan LM, Ballard CG, Allen J, Murray A, Davidson AW, McKeith IG, Kenny RA (2007). Autonomic dysfunction in dementia. J Neurol Neurosurg Psychiatry, 78(7), 671-677. Abstract.  Author URL.
McKeith IG, Rowan E, Askew K, Naidu A, Allan L, Barnett N, Lett D, Mosimann UP, Burn D, O'Brien JT, et al (2006). More severe functional impairment in dementia with Lewy bodies than Alzheimer disease is related to extrapyramidal motor dysfunction. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 14(7), 582-588. Author URL.
Burn DJ, Rowan EN, Allan LM, Molloy S, T O'Brien J, McKeith IG (2006). Motor subtype and cognitive decline in Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bodies. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 77(5), 585-589. Author URL.
Allan L, McKeith I, Ballard C, Kenny RA (2006). The prevalence of autonomic symptoms in dementia and their association with physical activity, activities of daily living and quality of life. Dementia and Geriatric Cognitive Disorders, 22(3), 230-237. Abstract.
Allan LM, Kerr SRJ, Ballard CG, Allen J, Murray A, McLaren AT, Kenny RA (2005). Autonomic function assessed by heart rate variability is normal in Alzheimer's disease and vascular dementia. Dement Geriatr Cogn Disord, 19(2-3), 140-144. Abstract.  Author URL.
McLaren A, Kerr S, Allan L, Steen IN, Ballard C, Allen J, Murray A, Kenny RA (2005). Autonomic function is impaired in elderly stroke survivors. Stroke, 36(5), 1026-1030. Abstract.  Author URL.
Allan LM, Ballard CG, Burn DJ, Kenny RA (2005). Prevalence and severity of gait disorders in Alzheimer's and non-Alzheimer's dementias. Journal of the American Geriatrics Society, 53(10), 1681-1687. Abstract.
Allan L, Johns E, Doshi M, Kenny RA, Newton JL (2004). Abnormalities of sympathetic and parasympathetic autonomic function in subjects with defaecation syncope. EUROPACE, 6(3), 192-198. Author URL.
Stephens S, Kenny RA, Rowan E, Allan L, Kalaria RN, Bradbury M, Ballard CG (2004). Neuropsychological characteristics of mild vascular cognitive impairment and dementia after stroke. International Journal of Geriatric Psychiatry, 19(11), 1053-1057. Abstract.
Newton JL, Allan L, Baptist M, Kenny R (2001). Defecation syncope associated with splanchnic sympathetic dysfunction and cured by permanent pacemaker insertion. AMERICAN JOURNAL OF GASTROENTEROLOGY, 96(7), 2276-2278. Author URL.
Williams JH, Wellman NA, Allan LM, Taylor E, Tonin J, Feldon J, Rawlins JNP (1996). Tobacco smoking correlates with schizotypal and borderline personality traits. PERSONALITY AND INDIVIDUAL DIFFERENCES, 20(2), 267-270. Author URL.
ALLAN LM, WILLIAMS JH, WELLMAN NA, TONIN J, TAYLOR E, FELDON J, RAWLINS JNP (1995). EFFECTS OF TOBACCO SMOKING, SCHIZOTYPY AND NUMBER OF PRE-EXPOSURES ON LATENT INHIBITION IN HEALTHY-SUBJECTS. PERSONALITY AND INDIVIDUAL DIFFERENCES, 19(6), 893-902. Author URL.

Chapters

Kenny RA, Allan LM (2005). Autonomic dysfunction in dementia with lewy bodies. In  (Ed) Dementia with Lewy Bodies: and Parkinson's Disease Dementia, 107-128.  Abstract.

Conferences

Robalino S, Nyakang'o SB, Beyer F, Fox C, Allan LM (2018). EFFECTIVENESS OF INTERVENTIONS AIMED AT IMPROVING PHYSICAL AND PSYCHOLOGICAL OUTCOMES OF FALL-RELATED INJURIES IN PEOPLE WITH DEMENTIA: a SYSTEMATIC REVIEW.  Author URL.
McCormack V, Allan L, Davis D, Richardson S, Steffan B (2017). WHAT IS THE EFFECT OF DELIRIUM UPON THE TRAJECTORY OF COGNITIVE DECLINE IN THE LEWY BODY DISORDERS? a RETROSPECTIVE EXAMINATION OF EPISODES OF DELIRIUM IN a LONGITUDINAL COHORT OF PEOPLE WITH PARKINSON'S DISEASE (PD), PARKINSON'S DISEASE DEMENTIA (PDD) AND DEMENTIA WITH LEWY BODIES (DLB).  Author URL.
Chen A, Akinyemi RO, Washida K, Foster V, Firbank MJ, Oakley AE, Okamoto Y, O'Brien JT, Allan LM, Ihara M, et al (2015). Frontal white matter clasmatodendrosis and cognitive dysfunction in the elderly.  Author URL.
Akinyemi RO, Allan L, Ogunniyi A, Kalaria RN (2014). Profile and determinants associated with vascular cognitive impairment in African stroke survivors: the CogFAST - Nigeria study.  Author URL.
Kuhn E, O'Regan N, McGrath K, Coveney S, Du XY, Teodorczuk A, Allan L, Wilson D, MacLullich A, Meagher D, et al (2013). Consensus Validation of a Method for Delirium Identification Using Hospital Records.  Author URL.
Allan LM, Ballard CG, Allen J, Murray A, Davidson A, Kenny R (2005). Autonomic dysfunction is present in dementia with Lewy bodies.  Author URL.
Allan LM, Ballard CG, Davidson A, Kenny R (2005). Prevalence of orthostatic hypotension in common dementia disorders.  Author URL.
Allan LM, Burn DJ, Ballard CG, Kenny R (2004). Early presentation of gait disorder is indicative of non-Alzheimer's dementia.  Author URL.
Mosimann UP, Felblinger J, Muri RM, Allan L, Pakrasi S, Bowman LC, O'Brien JT (2003). Saccadic eye movements in dementia with Lewy bodies.  Author URL.
Allan L, Johns CE, Doshi M, Newton JL (2002). Defecation syncope is associated with abnormalities of sympathetic and parasympathetic autonomic nervous function.  Author URL.

Publications by year


In Press

Robalino S, Nyakang'o SB, Beyer FR, Fox C, Allan LM (In Press). Effectiveness of interventions aimed at improving physical and psychological outcomes of fall-related injuries in people with dementia: a narrative systematic review. Syst Rev, 7(1). Abstract.  Author URL.

2018

Kane JPM, Surendranathan A, Bentley A, Barker SAH, Taylor J-P, Thomas AJ, Allan LM, McNally RJ, James PW, McKeith IG, et al (2018). Clinical prevalence of Lewy body dementia. ALZHEIMERS RESEARCH & THERAPY, 10 Author URL.
Robalino S, Nyakang'o SB, Beyer F, Fox C, Allan LM (2018). EFFECTIVENESS OF INTERVENTIONS AIMED AT IMPROVING PHYSICAL AND PSYCHOLOGICAL OUTCOMES OF FALL-RELATED INJURIES IN PEOPLE WITH DEMENTIA: a SYSTEMATIC REVIEW.  Author URL.
Bamford C, Wheatley A, Shaw C, Allan LM (2018). Equipping staff with the skills to maximise recovery of people with dementia after an injurious fall. Aging Ment Health, 1-9. Abstract.  Author URL.
Allan LM, Wheatley A, Flynn E, Smith A, Fox C, Howel D, Barber R, Homer TM, Robinson L, Parry SW, et al (2018). Is it feasible to deliver a complex intervention to improve the outcome of falls in people with dementia? a protocol for the DIFRID feasibility study. Pilot Feasibility Stud, 4 Abstract.  Author URL.
Goodwin V, Allan L (2018). Mrs Smith has no rehab potential”: Does rehabilitation have a role in the management of people with dementia. Age and Ageing Full text.
Connors MH, Quinto L, McKeith I, Brodaty H, Allan L, Bamford C, Thomas A, Taylor J-P, O'Brien JT (2018). Non-pharmacological interventions for Lewy body dementia: a systematic review. Psychol Med, 48(11), 1749-1758. Abstract.  Author URL.
Skrobot OA, Black SE, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, O'Brien J, Pantoni L, Pasquier F, et al (2018). Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study. ALZHEIMERS & DEMENTIA, 14(3), 280-292. Author URL.
Thomas AJ, Taylor JP, McKeith I, Bamford C, Burn D, Allan L, O'Brien J (2018). Revision of assessment toolkits for improving the diagnosis of Lewy body dementia: the DIAMOND Lewy study. Int J Geriatr Psychiatry, 33(10), 1293-1304. Author URL.

2017

Barnfield S, Pitts AC, Kalaria R, Allan L, Tullo E (2017). "Is all the stuff about neurons necessary?" the development of lay summaries to disseminate findings from the Newcastle Cognitive Function after Stroke (COGFAST) study. Res Involv Engagem, 3 Abstract.  Author URL.
Thomas AJ, Taylor JP, McKeith I, Bamford C, Burn D, Allan L, O'Brien J (2017). Development of assessment toolkits for improving the diagnosis of the Lewy body dementias: feasibility study within the DIAMOND Lewy study. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 32(12), 1280-1304. Author URL.
Akinyemi RO, Allan LM, Oakley A, Kalaria RN (2017). Hippocampal Neurodegenerative Pathology in Post-stroke Dementia Compared to Other Dementias and Aging Controls. FRONTIERS IN NEUROSCIENCE, 11 Author URL.
Richardson SJ, Davis DHJ, Stephan B, Robinson L, Brayne C, Barnes L, Parker S, Allan LM (2017). Protocol for the Delirium and Cognitive Impact in Dementia (DECIDE) study: a nested prospective longitudinal cohort study. BMC GERIATRICS, 17 Author URL.
Sachdev PS, Lo JW, Crawford JD, Mellon L, Hickey A, Williams D, Bordet R, Mendyk A-M, Gelé P, Deplanque D, et al (2017). STROKOG (stroke and cognition consortium): an international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease. Alzheimers Dement (Amst), 7, 11-23. Abstract.  Author URL.
Skrobot OA, O'Brien J, Black S, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, Pantoni L, Pasquier F, et al (2017). The Vascular Impairment of Cognition Classification Consensus Study. ALZHEIMERS & DEMENTIA, 13(6), 624-633. Author URL.
McCormack V, Allan L, Davis D, Richardson S, Steffan B (2017). WHAT IS THE EFFECT OF DELIRIUM UPON THE TRAJECTORY OF COGNITIVE DECLINE IN THE LEWY BODY DISORDERS? a RETROSPECTIVE EXAMINATION OF EPISODES OF DELIRIUM IN a LONGITUDINAL COHORT OF PEOPLE WITH PARKINSON'S DISEASE (PD), PARKINSON'S DISEASE DEMENTIA (PDD) AND DEMENTIA WITH LEWY BODIES (DLB).  Author URL.

2016

Harrison SL, Tang EYH, Keage HAD, Taylor J-P, Allan L, Robinson L, Jagger C, Rockwood K, Stephan BCM (2016). A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 42(1-2), 69-79. Author URL.
Kane JPM, Richardson S, Allan L, Thomas A (2016). Diagnosing dementia. BRITISH JOURNAL OF HOSPITAL MEDICINE, 77(2), C22-C25. Author URL.
Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung'u MN, Foster V, Craggs LJL, Washida K, Okamoto Y, Thomas AJ, et al (2016). Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia. BRAIN, 139, 242-258. Author URL.
Dichgans M, Wardlaw J, Smith E, Zietemann V, Seshadri S, Sachdev P, Biessels GJ, Fazekas F, Benavente O, Pantoni L, et al (2016). METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: an initiative of the Joint Programme for Neurodegenerative Disease Research. ALZHEIMERS & DEMENTIA, 12(12), 1235-1249. Author URL.
Chen A, Oakley AE, Monteiro M, Tuomela K, Allan LM, Mukaetova-Ladinska EB, O'Brien JT, Kalaria RN (2016). Multiplex analyte assays to characterize different dementias: brain inflammatory cytokines in poststroke and other dementias. NEUROBIOLOGY OF AGING, 38, 56-67. Author URL.

2015

Chen A, Akinyemi RO, Washida K, Foster V, Firbank MJ, Oakley AE, Okamoto Y, O'Brien JT, Allan LM, Ihara M, et al (2015). Frontal white matter clasmatodendrosis and cognitive dysfunction in the elderly.  Author URL.
Akinyemi RO, Firbank M, Ogbole GI, Allan LM, Owolabi MO, Akinyemi JO, Yusuf BP, Ogunseyinde O, Ogunniyi A, Kalaria RN, et al (2015). Medial temporal lobe atrophy, white matter hyperintensities and cognitive impairment among Nigerian African stroke survivors. BMC Res Notes, 8 Abstract.  Author URL.
Tullo ES, Lee RP, Robinson L, Allan L (2015). Why is dementia different? Medical students' views about deceiving people with dementia. AGING & MENTAL HEALTH, 19(8), 731-738. Author URL.

2014

Mayne DJF, Allan L, Reynish E, MacLullich AMJ, Vardy ERLC (2014). Experience and opinions on post-graduate dementia training in the UK: a survey of selected consultant geriatricians. AGE AND AGEING, 43(2), 263-266. Author URL.
Gemmell E, Tam E, Allan L, Hall R, Khundakar A, Oakley AE, Thomas A, Deramecourt V, Kalaria RN (2014). Neuron Volumes in Hippocampal Subfields in Delayed Poststroke and Aging-Related Dementias. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 73(4), 305-311. Author URL.
Akinyemi RO, Allan L, Ogunniyi A, Kalaria RN (2014). Profile and determinants associated with vascular cognitive impairment in African stroke survivors: the CogFAST - Nigeria study.  Author URL.
Akinyemi RO, Allan L, Owolabi MO, Akinyemi JO, Ogbole G, Ajani A, Firbank M, Ogunniyi A, Kalaria RN (2014). Profile and determinants of vascular cognitive impairment in African stroke survivors: the CogFAST Nigeria Study. JOURNAL OF THE NEUROLOGICAL SCIENCES, 346(1-2), 241-249. Author URL.
Foster V, Oakley AE, Slade JY, Hall R, Polvikoski TM, Burke M, Thomas AJ, Khundakar A, Allan LM, Kalaria RN, et al (2014). Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias. BRAIN, 137, 2509-2521. Author URL.
Kuhn E, Du X, McGrath K, Coveney S, O'Regan N, Richardson S, Teodorczuk A, Allan L, Wilson D, Inouye SK, et al (2014). Validation of a Consensus Method for Identifying Delirium from Hospital Records. PLOS ONE, 9(11). Author URL.

2013

Kuhn E, O'Regan N, McGrath K, Coveney S, Du XY, Teodorczuk A, Allan L, Wilson D, MacLullich A, Meagher D, et al (2013). Consensus Validation of a Method for Delirium Identification Using Hospital Records.  Author URL.
Allan LM, Rowan EN, Thomas AJ, Polvikoski TM, O'Brien JT, Kalaria RN (2013). Long-term incidence of depression and predictors of depressive symptoms in older stroke survivors. BRITISH JOURNAL OF PSYCHIATRY, 203(6), 453-460. Author URL.

2012

Gemmell E, Bosomworth H, Allan L, Hall R, Khundakar A, Oakley AE, Deramecourt V, Polvikoski TM, O'Brien JT, Kalaria RN, et al (2012). Hippocampal Neuronal Atrophy and Cognitive Function in Delayed Poststroke and Aging-Related Dementias. STROKE, 43(3), 808-+. Author URL.
Firbank MJ, Allan LM, Burton EJ, Barber R, O'Brien JT, Kalaria RN (2012). Neuroimaging predictors of death and dementia in a cohort of older stroke survivors. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 83(3), 263-267. Author URL.

2011

Allan LM, Rowan EN, Firbank MJ, Thomas AJ, Parry SW, Polvikoski TM, O'Brien JT, Kalaria RN (2011). Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors. BRAIN, 134, 3713-3724. Author URL.
Morris CM, Ballard CG, Allan L, Rowan E, Stephens S, Firbank M, Ford GA, Kenny RA, O'Brien JT, Kalaria RN, et al (2011). NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors. Neurobiology of Aging, 32(3). Abstract.
Tullo E, Allan L (2011). What should we be teaching medical students about dementia?. INTERNATIONAL PSYCHOGERIATRICS, 23(7), 1044-1050. Author URL.

2010

Tullo ES, Spencer J, Allan L (2010). Systematic Review: Helping the Young to Understand the Old. Teaching Interventions in Geriatrics to Improve the Knowledge, Skills, and Attitudes of Undergraduate Medical Students. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 58(10), 1987-1993. Author URL.

2009

Miller VM, Kenny RA, Oakley AE, Hall R, Kalaria RN, Allan LM (2009). Dorsal Motor Nucleus of Vagus protein aggregates in Lewy Body Disease with autonomic dysfunction. BRAIN RESEARCH, 1286, 165-173. Author URL.
Allan LM, Ballard CG, Rowan EN, Kenny RA (2009). Incidence and prediction of falls in dementia: a prospective study in older people. PLoS ONE, 4(5). Abstract.

2007

Allan LM, Ballard CG, Allen J, Murray A, Davidson AW, McKeith IG, Kenny RA (2007). Autonomic dysfunction in dementia. J Neurol Neurosurg Psychiatry, 78(7), 671-677. Abstract.  Author URL.

2006

McKeith IG, Rowan E, Askew K, Naidu A, Allan L, Barnett N, Lett D, Mosimann UP, Burn D, O'Brien JT, et al (2006). More severe functional impairment in dementia with Lewy bodies than Alzheimer disease is related to extrapyramidal motor dysfunction. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 14(7), 582-588. Author URL.
Burn DJ, Rowan EN, Allan LM, Molloy S, T O'Brien J, McKeith IG (2006). Motor subtype and cognitive decline in Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bodies. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 77(5), 585-589. Author URL.
Allan L, McKeith I, Ballard C, Kenny RA (2006). The prevalence of autonomic symptoms in dementia and their association with physical activity, activities of daily living and quality of life. Dementia and Geriatric Cognitive Disorders, 22(3), 230-237. Abstract.

2005

Kenny RA, Allan LM (2005). Autonomic dysfunction in dementia with lewy bodies. In  (Ed) Dementia with Lewy Bodies: and Parkinson's Disease Dementia, 107-128.  Abstract.
Allan LM, Ballard CG, Allen J, Murray A, Davidson A, Kenny R (2005). Autonomic dysfunction is present in dementia with Lewy bodies.  Author URL.
Allan LM, Kerr SRJ, Ballard CG, Allen J, Murray A, McLaren AT, Kenny RA (2005). Autonomic function assessed by heart rate variability is normal in Alzheimer's disease and vascular dementia. Dement Geriatr Cogn Disord, 19(2-3), 140-144. Abstract.  Author URL.
McLaren A, Kerr S, Allan L, Steen IN, Ballard C, Allen J, Murray A, Kenny RA (2005). Autonomic function is impaired in elderly stroke survivors. Stroke, 36(5), 1026-1030. Abstract.  Author URL.
Allan LM, Ballard CG, Burn DJ, Kenny RA (2005). Prevalence and severity of gait disorders in Alzheimer's and non-Alzheimer's dementias. Journal of the American Geriatrics Society, 53(10), 1681-1687. Abstract.
Allan LM, Ballard CG, Davidson A, Kenny R (2005). Prevalence of orthostatic hypotension in common dementia disorders.  Author URL.

2004

Allan L, Johns E, Doshi M, Kenny RA, Newton JL (2004). Abnormalities of sympathetic and parasympathetic autonomic function in subjects with defaecation syncope. EUROPACE, 6(3), 192-198. Author URL.
Allan LM, Burn DJ, Ballard CG, Kenny R (2004). Early presentation of gait disorder is indicative of non-Alzheimer's dementia.  Author URL.
Stephens S, Kenny RA, Rowan E, Allan L, Kalaria RN, Bradbury M, Ballard CG (2004). Neuropsychological characteristics of mild vascular cognitive impairment and dementia after stroke. International Journal of Geriatric Psychiatry, 19(11), 1053-1057. Abstract.

2003

Mosimann UP, Felblinger J, Muri RM, Allan L, Pakrasi S, Bowman LC, O'Brien JT (2003). Saccadic eye movements in dementia with Lewy bodies.  Author URL.

2002

Allan L, Johns CE, Doshi M, Newton JL (2002). Defecation syncope is associated with abnormalities of sympathetic and parasympathetic autonomic nervous function.  Author URL.

2001

Newton JL, Allan L, Baptist M, Kenny R (2001). Defecation syncope associated with splanchnic sympathetic dysfunction and cured by permanent pacemaker insertion. AMERICAN JOURNAL OF GASTROENTEROLOGY, 96(7), 2276-2278. Author URL.

1996

Williams JH, Wellman NA, Allan LM, Taylor E, Tonin J, Feldon J, Rawlins JNP (1996). Tobacco smoking correlates with schizotypal and borderline personality traits. PERSONALITY AND INDIVIDUAL DIFFERENCES, 20(2), 267-270. Author URL.

1995

ALLAN LM, WILLIAMS JH, WELLMAN NA, TONIN J, TAYLOR E, FELDON J, RAWLINS JNP (1995). EFFECTS OF TOBACCO SMOKING, SCHIZOTYPY AND NUMBER OF PRE-EXPOSURES ON LATENT INHIBITION IN HEALTHY-SUBJECTS. PERSONALITY AND INDIVIDUAL DIFFERENCES, 19(6), 893-902. Author URL.

Louise_Allan Details from cache as at 2018-12-14 08:06:31

Refresh publications

External Engagment and Impact

Awards

  • 2008   Clinical Senior Lecturer Award (Hefce/UKCRN)
  • 2001   Clinical Research Fellowship, Alzheimer’s Society, UK
  • 1991   Martin Wronker prize for Medicine

(awarded for the highest 1st class honours degree in Physiological Sciences, Oxford University)


Committee/panel activities

 

  • 2009-present Dementia lead, Dementia and Related Disorders Section, British Geriatrics Society
  • 2015-present Right Care Task Force member, National Dementia Action Alliance (a taskforce of senior policymakers and clinicians coordinating the Dementia Friendly Hospitals campaign)
  • 2015-2018 Committee member, NICE Guideline Development Committee for Dementia

Invited lectures

  • Dementia: A tale of Anticholinergic burden. UK Continence Society Conference 2017

Teaching

Supervision / Group

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