COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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 Ling Li

Ling Li

Postdoctoral Research Associate

 01392 72 3898

 Medical School Building F.08C

 

Medical School Building, St Luke's Campus, Magdalen Road, Exeter, EX1 2LU, UK

Overview

During her MSc degree in Biochemistry in the University of Bristol, Ling took a special interest in alternative splicing. From there Ling applied for a PhD position in Bristol with Dr Sebastian Oltean (now working at University of Exeter) to study modulation of alternative splicing regulators during EMT in cancer progression. While finishing her PhD, Ling had developed an interest in detection of EGFR mutations in the plasma and urine of NSCLC patients and continued to do a Post-doc with Dr Sebastian Oltean in Exeter since August 2018. Ling have a postdoctoral research associate position at the University of Exeter to working with Dr Sebatian Oltean.

Ling is working on grants/funding obtained by Dr Sebastian Oltean from Boehringer Ingelheim.

 

Qualifications

  • PhD in Physiology, Pharmacology and Neuroscience (University of Bristol, 2014-now)
  • MSc in Biochemistry (University of Bristol, 2012-2013)
  • BSc in Bioscience (Southwest University, China, 2005-2009)

 

Research

Research interests

I am interested in alternative splicing in cancer, specifically, prostate cancer. Much of our research has been focused on alternative splicing regulators; however, our goals are to determine small molecules that are modulate splicing in prostate cancer, and to find out the mechanisms of these chemicals worked as a novel therapeutic way.

 

 

Research projects

Current projects:

  • Detection of genomic mutations in blood and urine free circulating tumour DNA in inoperable and metastatic lung adenocarcinoma harboring an EGFR mutation on tissue.
  •  Alternative splicing control in epithelial-mesenchymal transitions / ESRP splice factors in prostate cancer
  • Investigation of new treatments in mouse models of diabetes

Grants/Funding:

  • Boehringer Ingelheim

Teaching

Supervision / Group

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