COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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Dr Kim Gooding

Dr Kim Gooding

Postdoctoral Research Fellow

 01392 403088

 Diabetes and Vascular Research Centre 

Overview

Dr Kim Gooding graduated with a degree in Biomedical Science and was awarded a PhD in Medical Sciences from the University of Exeter. Kim is a senior member of the Diabetes and Vascular Medicine Research team within the NIHR Exeter Clinical Research Facility. In addition to her research

Kim’s research is primarily focused on examining the relationship between microvascular endothelial function and the vascular complications associated with type 2 diabetes and prediabetes. She also works closely with the Patient Public Involvement groups within the NIHR Exeter Clinical Research Facility.

Qualifications

  • PhD in Medical Science
  • BSc (Hons) in Biomedical Science

Research

Research interests

Kim’s research interests are to develop, lead and collaborate on a programme of work to examine the relationship between microvascular function and the vascular complications associated with type 2 diabetes and prediabetes, with particular interests in (1) the underlying pathogenesis of diabetic retinopathy and nephropathy, and whether novel imaging biomarkers may help identify individuals at risk of these complications and (2) the vascular actions of incretin based therapies.

Recent research activities have included being the co-lead on the multi-centre Diabetic Retinopathy imaging study that forms part of the Innovative Medicines Initiative (IMI) funded SUMMIT consortium. She also actively contributes to the development and management of multi-centre study funded by IMI investigating prognostic imaging biomarkers for diabetic kidney disease.

Her programme of studies examining the microvascular actions of incretin based medications, including the DPP-IV inhibitors and  GLP-1 receptor agonists, has been funded by Diabetes UK and has utilised a multi-disciplinary approach using in vitro, ex vivo and clinical studies approaches.

Research projects

Current Projects:

  • The vascular actions of glucagon-like peptide-1 analogues and its mediators in people with type 2 diabetes and diabetic retinopathy (VIBE study).
  • Examining the relationship between blood vessel health and kidney function in people with and without diabetes (BEAT-DKD Exeter).
  • The role of SGLT-2 co-transporter inhibitors on metabolite utilisation in people with type 2 diabetes (DAMES study).
  • An investigation into the mechanisms of action of incretin based anti-diabetic therapies in the human vasculature.
  • Is the glycocalyx marker, hyaluronic acid, associated with early signs of diabetic retinopathy, macular thickening and albuminuria?
  • Examining whether subtle changes in the retina are associated with vascular complications in people with type 2 diabetes.

Grants/Funding:

  • Diabetes UK: The vascular actions of glucagon-like peptide-1 analogues and its mediators in people with type 2 diabetes and diabetic retinopathy (VIBE study).
  • Innovative Medicines Initiative (IMI): Examining the relationship between blood vessel health and kidney function in people with and without diabetes (BEAT-DKD Exeter).
  • Astra Zeneca: The role of SGLT-2 co-transporter inhibitors on metabolite utilisation in people with type 2 diabetes (DAMES study).
  • Diabetes UK: An investigation into the mechanisms of action of incretin based anti-diabetic therapies in the human vasculature.
  • Northcott Devon Medical Foundation: Is the glycocalyx marker, hyaluronic acid, associated with early signs of diabetic retinopathy, macular thickening and albuminuria?

Papers

Metformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes: A nested, case-control study. Natali A, Nesti L, Venturi E, Shore AC, Khan F, Gooding K, Gates PE, Looker HC, Dove F, Goncalves I, Persson M, Nilsson J; SUMMIT consortium. Diabetes Obes Metab. 2018 Sep 3. doi: 10.1111/dom.13519.

Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: The SUMMIT VIP Study. Shore AC, Colhoun HM, Natali A, Palombo C, Khan F, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, Gates PE, Looker H, Dove F, Belch J, Pinnola S, Venturi E, Kozakova M, Goncalves I, Kravic J, Björkbacka H, Nilsson J; SUMMIT Consortium. Diabetes Care. 2018;41(10):2212-2219.

The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control. Casanova F, Adingupu DD, Adams F, Gooding KM, Looker HC, Aizawa K, Dove F, Elyas S, Belch JJF, Gates PE, Littleford RC, Gilchrist M, Colhoun HM, Shore AC, Khan F, Strain WD. Cardiovasc Diabetol. 2017;16(1):114. doi: 10.1186/s12933-017-0594-7.

GLP-1 analogue-induced weight loss does not improve obesity-induced AT dysfunction. Pastel E, McCulloch LJ, Ward R, Joshi S, Gooding KM, Shore AC, Kos K. Clin Sci (Lond). 2017;131(5):343-353.

Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. Gonçalves I, Edsfeldt A, Colhoun HM, Shore AC, Palombo C, Natali A, Fredrikson GN, Björkbacka H, Wigren M, Bengtsson E, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Gates P, Khan F, Looker HC, Adams F, Belch J, Pinnola S, Venturi E, Kozakova M, Gan LM, Schnecke V, Nilsson J; SUMMIT consortium. BMC Cardiovasc Disord. 2016 ;16(1):171. doi: 10.1186/s12872-016-0346-8

Reactivity to low-flow as a potential determinant for brachial artery flow-mediated vasodilatation. Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Strain WD, Shore AC, Gates PE. Physiol Rep. 2016 Jun;4(12). pii: e12808. doi: 10.14814/phy2.12808.

Red Blood Cell Susceptibility to Pneumolysin: correlation with membrane biochemical and physical properties. Bokori-Brown M, Petrov PG, Khafaji MA, Mughal MK, Naylor CE, Shore AC, Gooding KM, Casanova F, Mitchell TJ, Titball RW, Winlove CP. J Biol Chem. 2016;291(19):10210-27.

Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Shore AC, Strain WD, Gates PE. Ultrasound Med Biol. 2016 ;42(5):1130-7.

Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes. Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Strain D, Khan F, Looker HC, Adams F, Belch J, Pinnoli S, Venturi E, Kozakova M, Gan LM, Schnecke V, Nilsson J; SUMMIT Consortium. Arterioscler Thromb Vasc Biol. 2015;35(7):1723-31.

Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, Gates PE, Khan F, Looker HC, Adams F, Belch J, Pinnoli S, Venturi E, Morizzo C, Goncalves I, Ladenvall C, Nilsson J; SUMMIT consortium. J Intern Med. 2015;278(3):291-302.

Blood Oxygen Saturation After Ischemia is Altered With Abnormal Microvascular Reperfusion. Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW. Microcirculation. 2015;22(4):294-305.

Ethnic differences in microvascular function in apparently healthy South African men and women. Pienaar PR, Micklesfield LK, Gill JM, Shore AC, Gooding KM, Levitt NS, Lambert EV. Exp Physiol. 2014;99(7):985-94.

Detection of hydrogen sulfide in plasma and knee-joint synovial fluid from rheumatoid arthritis patients: relation to clinical and laboratory measures of inflammation. Whiteman M, Haigh R, Tarr JM, Gooding KM, Shore AC, Winyard PG. Ann N Y Acad Sci. 2010;1203:146-50.

Capillary pressure may predict preclinical changes in the eye. Gooding KM, Tooke JE, von Lany H, Mitra M, Ling R, Ball CI, Mawson D, Skinner K, Shore AC. Diabetologia. 2010;53(9):2029-35.

Adiposity is a major determinant of plasma levels of the novel vasodilator hydrogen sulphide. Whiteman M, Gooding KM, Whatmore JL, Ball CI, Mawson D, Skinner K, Tooke JE, Shore AC.Diabetologia. 2010;53(8):1722-6.

Variability in sublingual microvessel density and flow measurements in healthy volunteers. Hubble SM, Kyte HL, Gooding K, Shore AC. Microcirculation. 2009;16(2):183-91.

The insulin sensitiser pioglitazone does not influence skin microcirculatory function in patients with type 2 diabetes treated with insulin. Tooke JE, Elston LM, Gooding KM, Ball CI, Mawson DM, Piper J, Sriraman R, Urquhart R, Shore AC. Diabetologia. 2006;49(5):1064-70.

Maximum skin hyperaemia induced by local heating: possible mechanisms. Gooding KM, Hannemann MM, Tooke JE, Clough GF, Shore AC. J Vasc Res. 2006;43(3):270-7.

Impact of hormone replacement therapy on microvascular function in healthy and Type 2 diabetic postmenopausal women. Gooding KM, MacLeod KM, Spyer G, Ewings P, Tooke JE, Shore AC. Diabet Med. 2005;22(5):536-42.

Serum amino acids in patients with mutations in the hepatocyte nuclear factor-1 alpha gene. Stride A, Pearson ER, Brown A, Gooding K, Castleden HA, Hattersley AT. Diabet Med. 2004;21(8):928-30.

Capillary pressure in subjects with type 2 diabetes and hypertension and the effect of antihypertensive therapy. Fegan PG, Tooke JE, Gooding KM, Tullett JM, MacLeod KM, Shore AC. Hypertension. 2003;41(5):1111-7.

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Gonçalves I, Edsfeldt A, Colhoun HM, Shore AC, Palombo C, Natali A, Fredrikson GN, Björkbacka H, Wigren M, Bengtsson E, et al (In Press). Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. BMC Cardiovasc Disord, 16(1). Abstract.  Author URL.  Full text.
To C, Rees-Lee JE, Gush RJ, Gooding KM, Cawrse NH, Shore AC, Wilson ADH (In Press). Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: a Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction. Plast Reconstr Surg, 143(2), 287e-292e. Abstract.  Author URL.  Full text.
Natali A, Nesti L, Venturi E, Shore AC, Khan F, Gooding K, Gates PE, Looker HC, Dove F, Goncalves I, et al (In Press). Metformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes: a nested, case-control study. Diabetes Obes Metab, 21(2), 412-416. Abstract.  Author URL.  Full text.
Casanova F, Adingupu DD, Adams F, Gooding KM, Looker HC, Aizawa K, Dove F, Elyas S, Belch JJF, Gates PE, et al (In Press). The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control. Cardiovasc Diabetol, 16(1). Abstract.  Author URL.  Full text.
Shore AC, Colhoun HM, Natali A, Palombo C, Khan F, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, et al (In Press). Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: the SUMMIT VIP Study. Diabetes Care, 41(10), 2212-2219. Abstract.  Author URL.  Full text.
Aung MM, Slade K, Freeman LAR, Kos K, Whatmore JL, Shore AC, Gooding KM (2019). Locally delivered GLP-1 analogues liraglutide and exenatide enhance microvascular perfusion in individuals with and without type 2 diabetes. Diabetologia, 62(9), 1701-1711. Abstract.  Author URL.  Full text.
Chapman DP, Gooding KM, McDonald TJ, Shore AC (2019). Stability of urinary albumin and creatinine after 12 months storage at -20 °C and -80 °C. Pract Lab Med, 15 Abstract.  Author URL.
Pastel E, McCulloch LJ, Ward R, Joshi S, Gooding KM, Shore AC, Kos K (2017). GLP-1 analogue-induced weight loss does not improve obesity-induced AT dysfunction. Clin Sci (Lond), 131(5), 343-353. Abstract.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Shore AC, Strain WD, Gates PE (2016). Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. Ultrasound Med Biol, 42(5), 1130-1137. Abstract.  Author URL.  Full text.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Strain WD, Shore AC, Gates PE (2016). Reactivity to low-flow as a potential determinant for brachial artery flow-mediated vasodilatation. Physiol Rep, 4(12). Abstract.  Author URL.  Full text.
Bokori-Brown M, Petrov PG, Khafaji MA, Mughal MK, Naylor CE, Shore AC, Gooding KM, Casanova F, Mitchell TJ, Titball RW, et al (2016). Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES. J Biol Chem, 291(19), 10210-10227. Abstract.  Author URL.  Full text.
Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW, et al (2015). Blood Oxygen Saturation After Ischemia is Altered with Abnormal Microvascular Reperfusion. Microcirculation, 22(4), 294-305. Abstract.  Author URL.
Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, et al (2015). Elevated Plasma Levels of MMP-12 Are Associated with Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects with Type 2 Diabetes. Arterioscler Thromb Vasc Biol, 35(7), 1723-1731. Abstract.  Author URL.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. Journal of Internal Medicine, 278(3), 291-302. Abstract.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. J Intern Med, 278(3), 291-302. Abstract.  Author URL.
Pienaar PR, Micklesfield LK, Gill JMR, Shore AC, Gooding KM, Levitt NS, Lambert EV (2014). Ethnic differences in microvascular function in apparently healthy South African men and women. Experimental Physiology, 99(7), 985-994. Abstract.
Pienaar PR, Micklesfield LK, Gill JMR, Shore AC, Gooding KM, Levitt NS, Lambert EV (2014). Ethnic differences in microvascular function in apparently healthy South African men and women. Exp Physiol, 99(7), 985-994. Abstract.  Author URL.
Pienaar PR, Micklesfield LK, Levitt NS, Gooding K, Shore AC, Goedecke JH, Gill JMR, Lambert EV (2014). Insulin Resistance is Associated with Lower Acetylcholine-Induced Microvascular Reactivity in Nondiabetic Women. Metabolic Syndrome and Related Disorders, 12(3), 178-184. Abstract.
Gooding KM, Shore AC, von Lany H, Ling R, Mitra M, Ball CI, Mawson D, Tooke JE (2012). Are features of the metabolic syndrome associated with macular thickness in individuals without diabetes mellitus?. Clinical and Experimental Ophthalmology, 3, 7-7.
Whiteman M, Gooding KM, Whatmore JL, Ball CI, Mawson D, Skinner K, Tooke JE, Shore AC (2010). Adiposity is a major determinant of plasma levels of the novel vasodilator hydrogen sulphide. Diabetologia, 53(8), 1722-1726. Abstract.  Author URL.
Gooding KM, Tooke JE, von Lany H, Mitra M, Ling R, Ball CI, Mawson D, Skinner K, Shore AC (2010). Capillary pressure may predict preclinical changes in the eye. Diabetologia, 53(9), 2029-2035. Abstract.  Author URL.  Full text.
Whiteman M, Haigh R, Tarr JM, Gooding KM, Shore AC, Winyard PG (2010). Detection of hydrogen sulfide in plasma and knee-joint synovial fluid from rheumatoid arthritis patients: relation to clinical and laboratory measures of inflammation. Ann N Y Acad Sci, 1203, 146-150. Abstract.  Author URL.
Hubble SMA, Kyte HL, Gooding K, Shore AC (2009). Variability in sublingual microvessel density and flow measurements in healthy volunteers. Microcirculation, 16(2), 183-191. Abstract.  Author URL.
Gooding KM, Spyer G, Tooke JE, MacLeod KM (2007). Alteration of oestradiol, testosterone, gonadotrophins and SHBG by type 2 diabetes in postmenopausal women: Clinical implications for the incidence of breast cancer, and cardiovascular risk in diabetic women?. Practical Diabetes International, 24(9), 465-470. Abstract.
Gooding KM, Hannemann MM, Tooke JE, Clough GF, Shore AC (2006). Maximum skin hyperaemia induced by local heating: possible mechanisms. J Vasc Res, 43(3), 270-277. Abstract.  Author URL.
JTooke, Ball C, Elston L, Gooding K (2006). The insulin sensitiser pioglitazone does not influence skin microcirculatory function in patients with type 2 diabetes treated with insulin. Diabetologia, 49(5), 1064-1070.
Tooke JE, Elston LM, Gooding KM, Ball CI, Mawson DM, Piper J, Sriraman R, Urquhart R, Shore AC (2006). The insulin sensitiser pioglitazone does not influence skin microcirculatory function in patients with type 2 diabetes treated with insulin. Diabetologia, 49(5), 1064-1070. Abstract.  Author URL.
Gooding KM, MacLeod KM, Spyer G, Ewings P, Tooke JE, Shore AC (2005). Impact of hormone replacement therapy on microvascular function in healthy and Type 2 diabetic postmenopausal women. Diabet Med, 22(5), 536-542. Abstract.  Author URL.
Stride A, Pearson ER, Brown A, Gooding K, Castleden HAJ, Hattersley AT (2004). Serum amino acids in patients with mutations in the hepatocyte nuclear factor-1 alpha gene. Diabet Med, 21(8), 928-930. Abstract.  Author URL.
Fegan PG, Tooke JE, Gooding KM, Tullett JM, MacLeod KM, Shore AC (2003). Capillary pressure in subjects with type 2 diabetes and hypertension and the effect of antihypertensive therapy. Hypertension, 41(5), 1111-1117. Abstract.  Author URL.

Conferences

Gooding K, Chapman D, Casanova F, Ball C, Whatmore JL, Ling R, Shore AC (2019). A PRELIMINARY STUDY EXAMINING ALBUMINURIA, MACULAR THICKNESS AND GLYCOCALYX SHEDDING IN THE EARLY STAGES OF DIABETIC RETINOPATHY IN TYPE 2 DIABETES.  Author URL.
Gooding K, Casanova F, Cox D, Ball C, Aizawa K, Mawson D, Shore A (2019). Association Between Sural Nerve Conductance Amplitude and Skin Microvascular Responsiveness in Individuals with and without Type 2 Diabetes Across the Subclinical Neuropathy Range.  Author URL.
Meakin PJ, Tuharska Z, Gooding KM, Casanova F, Shore AC, Ashford MLJ, Khan F (2018). Association between beta-amyloid, diabetes and endothelial function in humans.  Author URL.
Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Ostling G, Nilsson J, Khan F, Colhoun HM, et al (2018). PARAMETERS DERIVED FROM RESERVOIR PRESSURE ANALYSIS INDEPENDENTLY PREDICT CARDIOVASCULAR EVENTS IN a MULTI-CENTRE STUDY OF INDIVIDUALS WITH TYPE 2 DIABETES.  Author URL.
Ball C, Casanova F, Shore AC, Anning CM, Cox D, Gooding KM (2018). Participant feedback on strategies implemented to maintain participant engagement in a longitudinal, observational clinical study.  Author URL.
Casanova F, Adingupu DD, Gooding KM, Aizawa K, Gates PE, Elyas S, Shore AC, Strain DW (2017). Association Between Renal Function and Matrix Metalloproteinases in Type 2 Diabetes.  Author URL.
Gooding K, Shore AC, Casanova F, Colhoun HM, Looker HC, Leese GP, Agardh E (2017). EXAMINING LONGITUDINAL CHANGES OF MACULAR THICKNESS IN THE EARLY STAGES OF DIABETIC RETINOPATHY.  Author URL.
Gooding K, Mayne T, Casanova F, Ball C, Cox D, Ling R, Shore A (2017). Exploring the Relationship Between Retinal Micro-aneurysms with Plasma Levels of Matrix Metal-loproteinases and Growth Factors in Type 2 Diabetes.  Author URL.
Aizawa K, Casanova F, Mawson DM, Gooding KM, Park CM, Elyas S, Adingupu DD, Strain WD, Parker KH, Gates PE, et al (2017). RESERVOIR-PRESSURE ANALYSIS PREDICTS CARDIOVASCULAR EVENTS IN INDIVIDUALS WITH TYPE 2 DIABETES: a SINGLE-CENTRE STUDY.  Author URL.
Gooding KM, Shore AC, Ling R, Looker HC, Colhoun HM, Agardh E (2016). Assessment of using a retinal OCT phantom in multi-centre trials assessing macular thickness.  Author URL.
Freeman LAR, Gooding KM, Whatmore JL (2016). Incretin-based antidiabetic therapy induces microvascular endothelial cell proliferation, via AKT and PRAS40 phosphorylation.  Author URL.
Aizawa K, Casanova F, Mawson D, Elyas S, Adingupu DD, Gooding KM, Strain WD, Park CM, Parker KH, Gates PE, et al (2016). RESERVOIR-PRESSURE ANALYSIS IN TYPE 2 DIABETES INDIVIDUALS WITH CARDIOVASCULAR DISEASE.  Author URL.
Kos K, McCulloch LJ, Ward R, Joshi S, Sjoholm K, Pitt A, Gooding KM, Shore AC, Carlsson LMS (2015). Adipose tissue response to GLP-1 analogue-induced weight loss.  Author URL.
Gooding KM, Shore AC, Ling R, Agardh E (2015). An evaluation of different methods of normalising fovea thickness measurements from optical coherence tomography instruments.  Author URL.
Casanova F, Adingupu D, Gooding K, Strain D, Shore A (2015). DOES GLYCAEMIC CONTROL AFFECT MICROVASCULAR FUNCTION INDEPENDENT OF BLOOD PRESSURE IN TYPE 2 DIABETES?.  Author URL.
Aung MM, Gooding KM, Kos K, Shore AC (2015). Human, in vivo, microvascular actions of glucagon-like peptide 1 (GLP-1) and its analogues in health, obesity and well controlled Type 2 diabetes.  Author URL.
Gooding K, Shore A (2015). LDF MEASUREMENT - FROM THE LAB TO THE BEDSIDE.  Author URL.
Gooding K, Aung MM, Kos K, Shore A (2015). MICROVASCULAR ACTIONS OF GLUCAGON-LIKE PEPTIDE-1 AND ITS ANALOGUES IN LEAN AND OBESE PARTICIPANTS AND PARTICIPANTS WITH TYPE 2 DIABETES.  Author URL.
Aizawa K, Elyas S, Adingupu D, Casanova F, Gooding K, Mawson D, Shore A, Strain W, Gates P (2015). PP.20.26.
Freeman LAR, Gooding KM, Whatmore JL (2015). Proliferation effects of liraglutide on human microvascular endothelial cells.  Author URL.
Gooding KM, Shore AC, Ling R, Casanova F, Looker HC, Agardh E (2015). Regional differences in macular thickness in the early stages of diabetic retinopathy in type 2 diabetes.  Author URL.
Chapman DP, Gooding KM, McDonald TJ, Anning CM, Pamphilon N, Ball C, Casanova F, Shore AC (2015). Using clinical characteristics to account for variation of urinary creatinine excretion improves the accuracy of the albumin to creatinine ratio (ACR) to identify individuals with microalbuminuria.  Author URL.
Gooding KM, Shore AC, Ling R, Agardh E (2014). An evaluation of different methods of normalising fovea thickness measurements from optical coherence tomography instruments.  Author URL.
Aung MM, Gooding KM, Haynes LJ, Kos K, Shore AC (2014). Do glucagon like peptide-1 analogues alter microvascular function in healthy lean individuals?.  Author URL.
Clark C, Casanova F, Gooding K, Pamphilon N, Aizawa K, Mawson D, Adingupu D, Ball C, Worthington F, Elyas S, et al (2014). Inter-arm blood pressure difference and differences in arterial stiffness.  Author URL.
Gooding KM, Shore AC, Mawson D, Ball CI, Pitt A, Aizawa K, Strain WD (2013). A pilot study investigating whether dipeptidyl peptidase-IV inhibition alters vascular function in obese men.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Mawson DM, Shore AC, Strain WD, Gates PE (2013). Carotid artery intima-media echogenicity and aortic stiffness in healthy middle-aged and older humans.  Author URL.
Ball CI, Pitt AJ, Shore AC, Kyte HL, Gooding KM (2013). Does the Finnish diabetes risk score simplify recruitment of research participants at a raised risk of diabetes?.  Author URL.
Strain WD, Elyas S, Gooding K, Eastwood H, Keenan S, Stewart J, James MA, Shore AC (2013). Microalbuminuria could improve risk prediction of stroke in patients with TIA and minor stroke: the Prognostic Markers of TIA Evolution (ProMOTE) pilot study.  Author URL.
Thorn C, Kyte H, Gooding K, Shore A (2011). A reduced measure of oxygen extraction observed in the cutaneous microcirculation of obese subjects compared to normals.  Author URL.
Gooding K, Shore A, von Lany H, Ling R, Mitra M, Ball C, Mawson D, Tooke J (2011). Are features of the metabolic syndrome associated with macular thickness in individuals without diabetes mellitus?.  Author URL.
Gooding K, Kyte H, Aung MM, Shore A (2011). Mechanisms underlying the microvascular actions of insulin in lean and obese individuals.  Author URL.
Whiteman M, Strain WD, Whatmore JL, Gooding K, Ball C, Mawson D, Tooke JE, Shore AC (2011). Sex differences in the association between plasma levels of the novel vasodilatory gas hydrogen sulfide, adiposity and micro- and macrovascular function in vivo.  Author URL.
Whiteman M, Gooding KM, Whatmore JL, Skinner K, Ball C, Tooke JE, Shore AC (2010). 026 Plasma levels of the novel vasodilatory gas hydrogen sulphide are associated with adiposity.
Whiteman M, Whatmore JL, Gooding KM, Ball CL, Mawson D, Skinner K, Tooke JE, Shore A (2009). PLASMA LEVELS OF THE NOVEL VASODILATORY GAS HYDROGEN SULFIDE (H2S) ARE ASSOCIATED WITH ADIPOSITY.  Author URL.
Whiteman M, Gooding K, Whatmore J, Ball CI, Mawson D, Skinner K, Shore AC (2009). Plasma Hydrogen Sulfide (H2S) and Correlations with Physical, Clinical and Vascular indices of Obesity, Metabolic Syndrome and type II Diabetes.  Author URL.
Whiteman M, Whatmore JL, Skinner K, Ball C, Gooding KM, Shore AC (2009). Plasma hydrogen sulphide: correlations with clinical indices of micro- and macrovascular function, obesity, metabolic syndrome and type II diabetes.  Author URL.
Gooding KM, Tooke JE, Ling R, von Lany H, Mitra M, Ball C, Mawson D, Shore AC (2008). Fovea thickness and capillary pressure in non-diabetic individuals.  Author URL.
Gorshunska MY, Gooding KM, Mawson DM, Ball CI, Piper J, Tooke JE, Shore AC (2006). Microvascular distensibility in Type 2 diabetic patients: Relationship to hypertension and insulin resistance.  Author URL.
Gooding KM, Whatmore JL, Tullett J, Middlebrooke AR, Demaine AG, Tooke JE, Shore AC (2006). Microvascular function is altered by polymorphisms in the promoter region of the aldose reductase gene in healthy subjects.  Author URL.
Gooding KM, Whatmore JL, Tullett J, Middlebrooke AR, Demaine AG, Jarvis D, Tooke JE, Shore AC (2006). The impact of polymorphisms in the promoter region of the aldose reductase gene on microvascular function in healthy subjects.  Author URL.
Urquhart R, Gooding KM, Elston LM, Sriraman R, Shore AC, Tooke JE (2005). Effect of pioglitazone on microcirculation parameters in patients with type 2 diabetes treated with insulin.  Author URL.
Urquhart R, Elston LM, Gooding KM, Sriraman R, Shore AC, Tooke JE (2005). The effect of pioglitazone on inflammatory markers in patients with type 2 diabetes treated with insulin.  Author URL.
AShore, Fegan P, Gooding K, Tooke J (2003). Capillary pressure in subjects with type 2 diabetes and hypertension and the effect of antihypertensive therapy.
Gooding KM, Spyer G, MacLeod KM, Shore AC (2003). The effect of hormone replacement therapy on microvascular function in type 2 diabetic and healthy postmenopausal women.  Author URL.
Gooding KM, Tooke JE, Shore AC (2002). Assessment of microvascular filtration coefficent during early and late phase of the menstrual cycle in females not taking the oral contraceptive pill.  Author URL.
Gooding KM, Shore AC (2000). The role of prostaglandins in the skin hyperaemic response during local heating.  Author URL.
Gooding KM, Tooke JE, Shore AC (1999). The time course of the skin hyperaemic response during local heating.  Author URL.

Publications by year


In Press

Gonçalves I, Edsfeldt A, Colhoun HM, Shore AC, Palombo C, Natali A, Fredrikson GN, Björkbacka H, Wigren M, Bengtsson E, et al (In Press). Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. BMC Cardiovasc Disord, 16(1). Abstract.  Author URL.  Full text.
To C, Rees-Lee JE, Gush RJ, Gooding KM, Cawrse NH, Shore AC, Wilson ADH (In Press). Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: a Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction. Plast Reconstr Surg, 143(2), 287e-292e. Abstract.  Author URL.  Full text.
Natali A, Nesti L, Venturi E, Shore AC, Khan F, Gooding K, Gates PE, Looker HC, Dove F, Goncalves I, et al (In Press). Metformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes: a nested, case-control study. Diabetes Obes Metab, 21(2), 412-416. Abstract.  Author URL.  Full text.
Casanova F, Adingupu DD, Adams F, Gooding KM, Looker HC, Aizawa K, Dove F, Elyas S, Belch JJF, Gates PE, et al (In Press). The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control. Cardiovasc Diabetol, 16(1). Abstract.  Author URL.  Full text.
Shore AC, Colhoun HM, Natali A, Palombo C, Khan F, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, et al (In Press). Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: the SUMMIT VIP Study. Diabetes Care, 41(10), 2212-2219. Abstract.  Author URL.  Full text.

2019

Gooding K, Chapman D, Casanova F, Ball C, Whatmore JL, Ling R, Shore AC (2019). A PRELIMINARY STUDY EXAMINING ALBUMINURIA, MACULAR THICKNESS AND GLYCOCALYX SHEDDING IN THE EARLY STAGES OF DIABETIC RETINOPATHY IN TYPE 2 DIABETES.  Author URL.
Gooding K, Casanova F, Cox D, Ball C, Aizawa K, Mawson D, Shore A (2019). Association Between Sural Nerve Conductance Amplitude and Skin Microvascular Responsiveness in Individuals with and without Type 2 Diabetes Across the Subclinical Neuropathy Range.  Author URL.
Aung MM, Slade K, Freeman LAR, Kos K, Whatmore JL, Shore AC, Gooding KM (2019). Locally delivered GLP-1 analogues liraglutide and exenatide enhance microvascular perfusion in individuals with and without type 2 diabetes. Diabetologia, 62(9), 1701-1711. Abstract.  Author URL.  Full text.
Chapman DP, Gooding KM, McDonald TJ, Shore AC (2019). Stability of urinary albumin and creatinine after 12 months storage at -20 °C and -80 °C. Pract Lab Med, 15 Abstract.  Author URL.

2018

Meakin PJ, Tuharska Z, Gooding KM, Casanova F, Shore AC, Ashford MLJ, Khan F (2018). Association between beta-amyloid, diabetes and endothelial function in humans.  Author URL.
Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Ostling G, Nilsson J, Khan F, Colhoun HM, et al (2018). PARAMETERS DERIVED FROM RESERVOIR PRESSURE ANALYSIS INDEPENDENTLY PREDICT CARDIOVASCULAR EVENTS IN a MULTI-CENTRE STUDY OF INDIVIDUALS WITH TYPE 2 DIABETES.  Author URL.
Ball C, Casanova F, Shore AC, Anning CM, Cox D, Gooding KM (2018). Participant feedback on strategies implemented to maintain participant engagement in a longitudinal, observational clinical study.  Author URL.

2017

Casanova F, Adingupu DD, Gooding KM, Aizawa K, Gates PE, Elyas S, Shore AC, Strain DW (2017). Association Between Renal Function and Matrix Metalloproteinases in Type 2 Diabetes.  Author URL.
Gooding K, Shore AC, Casanova F, Colhoun HM, Looker HC, Leese GP, Agardh E (2017). EXAMINING LONGITUDINAL CHANGES OF MACULAR THICKNESS IN THE EARLY STAGES OF DIABETIC RETINOPATHY.  Author URL.
Gooding K, Mayne T, Casanova F, Ball C, Cox D, Ling R, Shore A (2017). Exploring the Relationship Between Retinal Micro-aneurysms with Plasma Levels of Matrix Metal-loproteinases and Growth Factors in Type 2 Diabetes.  Author URL.
Pastel E, McCulloch LJ, Ward R, Joshi S, Gooding KM, Shore AC, Kos K (2017). GLP-1 analogue-induced weight loss does not improve obesity-induced AT dysfunction. Clin Sci (Lond), 131(5), 343-353. Abstract.  Author URL.
Aizawa K, Casanova F, Mawson DM, Gooding KM, Park CM, Elyas S, Adingupu DD, Strain WD, Parker KH, Gates PE, et al (2017). RESERVOIR-PRESSURE ANALYSIS PREDICTS CARDIOVASCULAR EVENTS IN INDIVIDUALS WITH TYPE 2 DIABETES: a SINGLE-CENTRE STUDY.  Author URL.

2016

Gooding KM, Shore AC, Ling R, Looker HC, Colhoun HM, Agardh E (2016). Assessment of using a retinal OCT phantom in multi-centre trials assessing macular thickness.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Shore AC, Strain WD, Gates PE (2016). Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. Ultrasound Med Biol, 42(5), 1130-1137. Abstract.  Author URL.  Full text.
Freeman LAR, Gooding KM, Whatmore JL (2016). Incretin-based antidiabetic therapy induces microvascular endothelial cell proliferation, via AKT and PRAS40 phosphorylation.  Author URL.
Aizawa K, Casanova F, Mawson D, Elyas S, Adingupu DD, Gooding KM, Strain WD, Park CM, Parker KH, Gates PE, et al (2016). RESERVOIR-PRESSURE ANALYSIS IN TYPE 2 DIABETES INDIVIDUALS WITH CARDIOVASCULAR DISEASE.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Strain WD, Shore AC, Gates PE (2016). Reactivity to low-flow as a potential determinant for brachial artery flow-mediated vasodilatation. Physiol Rep, 4(12). Abstract.  Author URL.  Full text.
Bokori-Brown M, Petrov PG, Khafaji MA, Mughal MK, Naylor CE, Shore AC, Gooding KM, Casanova F, Mitchell TJ, Titball RW, et al (2016). Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES. J Biol Chem, 291(19), 10210-10227. Abstract.  Author URL.  Full text.

2015

Kos K, McCulloch LJ, Ward R, Joshi S, Sjoholm K, Pitt A, Gooding KM, Shore AC, Carlsson LMS (2015). Adipose tissue response to GLP-1 analogue-induced weight loss.  Author URL.
Gooding KM, Shore AC, Ling R, Agardh E (2015). An evaluation of different methods of normalising fovea thickness measurements from optical coherence tomography instruments.  Author URL.
Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW, et al (2015). Blood Oxygen Saturation After Ischemia is Altered with Abnormal Microvascular Reperfusion. Microcirculation, 22(4), 294-305. Abstract.  Author URL.
Casanova F, Adingupu D, Gooding K, Strain D, Shore A (2015). DOES GLYCAEMIC CONTROL AFFECT MICROVASCULAR FUNCTION INDEPENDENT OF BLOOD PRESSURE IN TYPE 2 DIABETES?.  Author URL.
Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, et al (2015). Elevated Plasma Levels of MMP-12 Are Associated with Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects with Type 2 Diabetes. Arterioscler Thromb Vasc Biol, 35(7), 1723-1731. Abstract.  Author URL.
Aung MM, Gooding KM, Kos K, Shore AC (2015). Human, in vivo, microvascular actions of glucagon-like peptide 1 (GLP-1) and its analogues in health, obesity and well controlled Type 2 diabetes.  Author URL.
Gooding K, Shore A (2015). LDF MEASUREMENT - FROM THE LAB TO THE BEDSIDE.  Author URL.
Gooding K, Aung MM, Kos K, Shore A (2015). MICROVASCULAR ACTIONS OF GLUCAGON-LIKE PEPTIDE-1 AND ITS ANALOGUES IN LEAN AND OBESE PARTICIPANTS AND PARTICIPANTS WITH TYPE 2 DIABETES.  Author URL.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. Journal of Internal Medicine, 278(3), 291-302. Abstract.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. J Intern Med, 278(3), 291-302. Abstract.  Author URL.
Aizawa K, Elyas S, Adingupu D, Casanova F, Gooding K, Mawson D, Shore A, Strain W, Gates P (2015). PP.20.26.
Freeman LAR, Gooding KM, Whatmore JL (2015). Proliferation effects of liraglutide on human microvascular endothelial cells.  Author URL.
Gooding KM, Shore AC, Ling R, Casanova F, Looker HC, Agardh E (2015). Regional differences in macular thickness in the early stages of diabetic retinopathy in type 2 diabetes.  Author URL.
Chapman DP, Gooding KM, McDonald TJ, Anning CM, Pamphilon N, Ball C, Casanova F, Shore AC (2015). Using clinical characteristics to account for variation of urinary creatinine excretion improves the accuracy of the albumin to creatinine ratio (ACR) to identify individuals with microalbuminuria.  Author URL.

2014

Gooding KM, Shore AC, Ling R, Agardh E (2014). An evaluation of different methods of normalising fovea thickness measurements from optical coherence tomography instruments.  Author URL.
Aung MM, Gooding KM, Haynes LJ, Kos K, Shore AC (2014). Do glucagon like peptide-1 analogues alter microvascular function in healthy lean individuals?.  Author URL.
Pienaar PR, Micklesfield LK, Gill JMR, Shore AC, Gooding KM, Levitt NS, Lambert EV (2014). Ethnic differences in microvascular function in apparently healthy South African men and women. Experimental Physiology, 99(7), 985-994. Abstract.
Pienaar PR, Micklesfield LK, Gill JMR, Shore AC, Gooding KM, Levitt NS, Lambert EV (2014). Ethnic differences in microvascular function in apparently healthy South African men and women. Exp Physiol, 99(7), 985-994. Abstract.  Author URL.
Pienaar PR, Micklesfield LK, Levitt NS, Gooding K, Shore AC, Goedecke JH, Gill JMR, Lambert EV (2014). Insulin Resistance is Associated with Lower Acetylcholine-Induced Microvascular Reactivity in Nondiabetic Women. Metabolic Syndrome and Related Disorders, 12(3), 178-184. Abstract.
Clark C, Casanova F, Gooding K, Pamphilon N, Aizawa K, Mawson D, Adingupu D, Ball C, Worthington F, Elyas S, et al (2014). Inter-arm blood pressure difference and differences in arterial stiffness.  Author URL.

2013

Gooding KM, Shore AC, Mawson D, Ball CI, Pitt A, Aizawa K, Strain WD (2013). A pilot study investigating whether dipeptidyl peptidase-IV inhibition alters vascular function in obese men.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Mawson DM, Shore AC, Strain WD, Gates PE (2013). Carotid artery intima-media echogenicity and aortic stiffness in healthy middle-aged and older humans.  Author URL.
Ball CI, Pitt AJ, Shore AC, Kyte HL, Gooding KM (2013). Does the Finnish diabetes risk score simplify recruitment of research participants at a raised risk of diabetes?.  Author URL.
Strain WD, Elyas S, Gooding K, Eastwood H, Keenan S, Stewart J, James MA, Shore AC (2013). Microalbuminuria could improve risk prediction of stroke in patients with TIA and minor stroke: the Prognostic Markers of TIA Evolution (ProMOTE) pilot study.  Author URL.

2012

Gooding KM, Shore AC, von Lany H, Ling R, Mitra M, Ball CI, Mawson D, Tooke JE (2012). Are features of the metabolic syndrome associated with macular thickness in individuals without diabetes mellitus?. Clinical and Experimental Ophthalmology, 3, 7-7.

2011

Thorn C, Kyte H, Gooding K, Shore A (2011). A reduced measure of oxygen extraction observed in the cutaneous microcirculation of obese subjects compared to normals.  Author URL.
Gooding K, Shore A, von Lany H, Ling R, Mitra M, Ball C, Mawson D, Tooke J (2011). Are features of the metabolic syndrome associated with macular thickness in individuals without diabetes mellitus?.  Author URL.
Gooding K, Kyte H, Aung MM, Shore A (2011). Mechanisms underlying the microvascular actions of insulin in lean and obese individuals.  Author URL.
Whiteman M, Strain WD, Whatmore JL, Gooding K, Ball C, Mawson D, Tooke JE, Shore AC (2011). Sex differences in the association between plasma levels of the novel vasodilatory gas hydrogen sulfide, adiposity and micro- and macrovascular function in vivo.  Author URL.

2010

Whiteman M, Gooding KM, Whatmore JL, Skinner K, Ball C, Tooke JE, Shore AC (2010). 026 Plasma levels of the novel vasodilatory gas hydrogen sulphide are associated with adiposity.
Whiteman M, Gooding KM, Whatmore JL, Ball CI, Mawson D, Skinner K, Tooke JE, Shore AC (2010). Adiposity is a major determinant of plasma levels of the novel vasodilator hydrogen sulphide. Diabetologia, 53(8), 1722-1726. Abstract.  Author URL.
Gooding KM, Tooke JE, von Lany H, Mitra M, Ling R, Ball CI, Mawson D, Skinner K, Shore AC (2010). Capillary pressure may predict preclinical changes in the eye. Diabetologia, 53(9), 2029-2035. Abstract.  Author URL.  Full text.
Whiteman M, Haigh R, Tarr JM, Gooding KM, Shore AC, Winyard PG (2010). Detection of hydrogen sulfide in plasma and knee-joint synovial fluid from rheumatoid arthritis patients: relation to clinical and laboratory measures of inflammation. Ann N Y Acad Sci, 1203, 146-150. Abstract.  Author URL.

2009

Whiteman M, Whatmore JL, Gooding KM, Ball CL, Mawson D, Skinner K, Tooke JE, Shore A (2009). PLASMA LEVELS OF THE NOVEL VASODILATORY GAS HYDROGEN SULFIDE (H2S) ARE ASSOCIATED WITH ADIPOSITY.  Author URL.
Whiteman M, Gooding K, Whatmore J, Ball CI, Mawson D, Skinner K, Shore AC (2009). Plasma Hydrogen Sulfide (H2S) and Correlations with Physical, Clinical and Vascular indices of Obesity, Metabolic Syndrome and type II Diabetes.  Author URL.
Whiteman M, Whatmore JL, Skinner K, Ball C, Gooding KM, Shore AC (2009). Plasma hydrogen sulphide: correlations with clinical indices of micro- and macrovascular function, obesity, metabolic syndrome and type II diabetes.  Author URL.
Hubble SMA, Kyte HL, Gooding K, Shore AC (2009). Variability in sublingual microvessel density and flow measurements in healthy volunteers. Microcirculation, 16(2), 183-191. Abstract.  Author URL.

2008

Gooding KM, Tooke JE, Ling R, von Lany H, Mitra M, Ball C, Mawson D, Shore AC (2008). Fovea thickness and capillary pressure in non-diabetic individuals.  Author URL.

2007

Gooding KM, Spyer G, Tooke JE, MacLeod KM (2007). Alteration of oestradiol, testosterone, gonadotrophins and SHBG by type 2 diabetes in postmenopausal women: Clinical implications for the incidence of breast cancer, and cardiovascular risk in diabetic women?. Practical Diabetes International, 24(9), 465-470. Abstract.

2006

Gooding KM, Hannemann MM, Tooke JE, Clough GF, Shore AC (2006). Maximum skin hyperaemia induced by local heating: possible mechanisms. J Vasc Res, 43(3), 270-277. Abstract.  Author URL.
Gorshunska MY, Gooding KM, Mawson DM, Ball CI, Piper J, Tooke JE, Shore AC (2006). Microvascular distensibility in Type 2 diabetic patients: Relationship to hypertension and insulin resistance.  Author URL.
Gooding KM, Whatmore JL, Tullett J, Middlebrooke AR, Demaine AG, Tooke JE, Shore AC (2006). Microvascular function is altered by polymorphisms in the promoter region of the aldose reductase gene in healthy subjects.  Author URL.
Gooding KM, Whatmore JL, Tullett J, Middlebrooke AR, Demaine AG, Jarvis D, Tooke JE, Shore AC (2006). The impact of polymorphisms in the promoter region of the aldose reductase gene on microvascular function in healthy subjects.  Author URL.
JTooke, Ball C, Elston L, Gooding K (2006). The insulin sensitiser pioglitazone does not influence skin microcirculatory function in patients with type 2 diabetes treated with insulin. Diabetologia, 49(5), 1064-1070.
Tooke JE, Elston LM, Gooding KM, Ball CI, Mawson DM, Piper J, Sriraman R, Urquhart R, Shore AC (2006). The insulin sensitiser pioglitazone does not influence skin microcirculatory function in patients with type 2 diabetes treated with insulin. Diabetologia, 49(5), 1064-1070. Abstract.  Author URL.

2005

Urquhart R, Gooding KM, Elston LM, Sriraman R, Shore AC, Tooke JE (2005). Effect of pioglitazone on microcirculation parameters in patients with type 2 diabetes treated with insulin.  Author URL.
Gooding KM, MacLeod KM, Spyer G, Ewings P, Tooke JE, Shore AC (2005). Impact of hormone replacement therapy on microvascular function in healthy and Type 2 diabetic postmenopausal women. Diabet Med, 22(5), 536-542. Abstract.  Author URL.
Urquhart R, Elston LM, Gooding KM, Sriraman R, Shore AC, Tooke JE (2005). The effect of pioglitazone on inflammatory markers in patients with type 2 diabetes treated with insulin.  Author URL.

2004

Stride A, Pearson ER, Brown A, Gooding K, Castleden HAJ, Hattersley AT (2004). Serum amino acids in patients with mutations in the hepatocyte nuclear factor-1 alpha gene. Diabet Med, 21(8), 928-930. Abstract.  Author URL.

2003

AShore, Fegan P, Gooding K, Tooke J (2003). Capillary pressure in subjects with type 2 diabetes and hypertension and the effect of antihypertensive therapy.
Fegan PG, Tooke JE, Gooding KM, Tullett JM, MacLeod KM, Shore AC (2003). Capillary pressure in subjects with type 2 diabetes and hypertension and the effect of antihypertensive therapy. Hypertension, 41(5), 1111-1117. Abstract.  Author URL.
Gooding KM, Spyer G, MacLeod KM, Shore AC (2003). The effect of hormone replacement therapy on microvascular function in type 2 diabetic and healthy postmenopausal women.  Author URL.

2002

Gooding KM, Tooke JE, Shore AC (2002). Assessment of microvascular filtration coefficent during early and late phase of the menstrual cycle in females not taking the oral contraceptive pill.  Author URL.

2000

Gooding KM, Shore AC (2000). The role of prostaglandins in the skin hyperaemic response during local heating.  Author URL.

1999

Gooding KM, Tooke JE, Shore AC (1999). The time course of the skin hyperaemic response during local heating.  Author URL.

Kim_Gooding Details from cache as at 2019-08-17 11:30:59

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External Engagement and Impact

Awards

  • British Microcirculation Society Poster Award 2009

Committee/panel activities

Kim is an active member of national and European societies for the microcirculation. Her involvement in the British Microcirculation Society includes:

  • Membership Secretary for the British Microcirculation Society (2014-2018)
  • Organising committee for the annual Society meetings in 2010 and 2019.
  • Chairing sessions and acting as poster judge at the annual meetings.

Kim is also a member of the Diabetes UK and the European Association for the Study of Diabetes.

Teaching

Teaching responsibilities: (Undergraduate, Postgraduate)

Current postgraduate supervision

Andrew Forbes Brown (Thesis title: Cross-sectional analysis of microvascular health in type 2 diabetic patients at differing stages of kidney function).

Natalia Rolinska (Thesis title: Examining whether subtle changes in the retina are associated with vascular complications in people with type 2 diabetes).

Leighton Freeman (Thesis title: An investigation into the mechanisms of action of incretin based anti-diabetic therapies in the human vasculature).

Undergraduate teaching responsibilities

BSc Medical Sciences

Academic tutor

Final year project provider

Professional training year supervisor

BMBS Medicine

Research in action special study unit provider

 

Supervision / Group

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