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Ms Joana Viana

Ms Joana Viana

Associate Research Fellow

01392 408162

RILD Building Level 4

Joana graduated in Cell and Molecular Biology at the Universidade Nova de Lisboa, Portugal, in 2011. She completed an MSc in Neuroscience at King’s College London in 2012. During this period, she developed a research project under the supervision of Dr Ruth Pidsley and Prof Jonathan Mill. The primary aim of her project was to access global methylation differences in post-mortem brain samples from schizophrenia patients and controls. From September of 2012 and January 2013 Joana worked as a research technician with the Psychiatric Epigenetics Group at King’s College London. She completed her PhD under the supervision of Prof Jonathan Mill and Dr Eduarda Santos in modelling epigenetic responses to schizophrenia-associated environmental risks and antipsychotic medication. She is currently a Postdoc working on the MATRICS project researching Disruptive Behaviour Disorder.

 

Qualifications

  • BSc in Cell and Molecular Biology
  • MSc in Neuroscience
  • PhD in Medical Studies

Research

Research interests

  • Epigenomics
  • Genomics
  • Transcriptomics
  • Psychiatry
  • Antipsychotic medication

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Viana J, Hannon E, Dempster E, Pidsley R, Macdonald R, Knox O, Spiers H, Troakes C, Al-Saraj S, Turecki G, et al (2017). Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions. Hum Mol Genet, 26(1), 210-225. Abstract.  Author URL.  Full text.
Hannon E, Dempster E, Viana J, Burrage J, Smith AR, Macdonald R, St Clair D, Mustard C, Breen G, Therman S, et al (2016). An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation. Genome Biol, 17(1). Abstract.  Author URL.  Full text.
Laing LV, Viana J, Dempster EL, Trznadel M, Trunkfield LA, Uren Webster TM, van Aerle R, Paull GC, Wilson RJ, Mill J, et al (2016). Bisphenol a causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio). Epigenetics, 11(7), 526-538. Abstract.  Author URL.  Full text.
Hannon E, Spiers H, Viana J, Pidsley R, Burrage J, Murphy TM, Troakes C, Turecki G, O'Donovan MC, Schalkwyk LC, et al (2016). Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci. Nat Neurosci, 19(1), 48-54. Abstract.  Author URL.  Full text.
Kumsta R, Marzi SJ, Viana J, Dempster EL, Crawford B, Rutter M, Mill J, Sonuga-Barke EJS (2016). Severe psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1. Transl Psychiatry, 6(6). Abstract.  Author URL.  Full text.
Fisher HL, Murphy TM, Arseneault L, Caspi A, Moffitt TE, Viana J, Hannon E, Pidsley R, Burrage J, Dempster EL, et al (2015). Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms. Epigenetics, 10(11), 1014-1023. Abstract.  Author URL.  Full text.
Viana J, Pidsley R, Troakes C, Spiers H, Wong CC, Al-Sarraj S, Craig I, Schalkwyk L, Mill J (2014). Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain. Epigenetics, 9(4), 587-599. Abstract.  Author URL.  Full text.
Pidsley R, Viana J, Hannon E, Spiers H, Troakes C, Al-Saraj S, Mechawar N, Turecki G, Schalkwyk LC, Bray NJ, et al (2014). Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia. GENOME BIOLOGY, 15(10). Author URL.  Full text.
Dempster E, Viana J, Pidsley R, Mill J (2013). Epigenetic studies of schizophrenia: progress, predicaments, and promises for the future. Schizophr Bull, 39(1), 11-16. Abstract.  Author URL.
Pidsley R, Fernandes C, Viana J, Paya-Cano JL, Liu L, Smith RG, Schalkwyk LC, Mill J (2012). DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice. Mol Brain, 5 Abstract.  Author URL.

Publications by year


2017

Viana J, Hannon E, Dempster E, Pidsley R, Macdonald R, Knox O, Spiers H, Troakes C, Al-Saraj S, Turecki G, et al (2017). Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions. Hum Mol Genet, 26(1), 210-225. Abstract.  Author URL.  Full text.

2016

Hannon E, Dempster E, Viana J, Burrage J, Smith AR, Macdonald R, St Clair D, Mustard C, Breen G, Therman S, et al (2016). An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation. Genome Biol, 17(1). Abstract.  Author URL.  Full text.
Laing LV, Viana J, Dempster EL, Trznadel M, Trunkfield LA, Uren Webster TM, van Aerle R, Paull GC, Wilson RJ, Mill J, et al (2016). Bisphenol a causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio). Epigenetics, 11(7), 526-538. Abstract.  Author URL.  Full text.
Hannon E, Spiers H, Viana J, Pidsley R, Burrage J, Murphy TM, Troakes C, Turecki G, O'Donovan MC, Schalkwyk LC, et al (2016). Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci. Nat Neurosci, 19(1), 48-54. Abstract.  Author URL.  Full text.
Kumsta R, Marzi SJ, Viana J, Dempster EL, Crawford B, Rutter M, Mill J, Sonuga-Barke EJS (2016). Severe psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1. Transl Psychiatry, 6(6). Abstract.  Author URL.  Full text.

2015

Fisher HL, Murphy TM, Arseneault L, Caspi A, Moffitt TE, Viana J, Hannon E, Pidsley R, Burrage J, Dempster EL, et al (2015). Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms. Epigenetics, 10(11), 1014-1023. Abstract.  Author URL.  Full text.

2014

Viana J, Pidsley R, Troakes C, Spiers H, Wong CC, Al-Sarraj S, Craig I, Schalkwyk L, Mill J (2014). Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain. Epigenetics, 9(4), 587-599. Abstract.  Author URL.  Full text.
Pidsley R, Viana J, Hannon E, Spiers H, Troakes C, Al-Saraj S, Mechawar N, Turecki G, Schalkwyk LC, Bray NJ, et al (2014). Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia. GENOME BIOLOGY, 15(10). Author URL.  Full text.

2013

Dempster E, Viana J, Pidsley R, Mill J (2013). Epigenetic studies of schizophrenia: progress, predicaments, and promises for the future. Schizophr Bull, 39(1), 11-16. Abstract.  Author URL.

2012

Pidsley R, Fernandes C, Viana J, Paya-Cano JL, Liu L, Smith RG, Schalkwyk LC, Mill J (2012). DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice. Mol Brain, 5 Abstract.  Author URL.

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