Journal articles
Atkins J (In Press). Hereditary hemochromatosis variant associations with incident non-liver malignancies: 11-year follow-up in UK Biobank. Cancer Epidemiology, Biomarkers and Prevention
Atkins J, Masoli J, Correa-Delgado J, Pilling L, Kuo C-L, Melzer D, Kuchel G (In Press). PREEXISTING COMORBIDITIES PREDICTING COVID-19 AND MORTALITY IN THE UK BIOBANK COMMUNITY COHORT. Journal of Gerontology Series A: Biological Sciences and Medical Sciences
Lucas MR, Atkins JL, Pilling LC, Shearman JD, Melzer D (2024). <i>HFE</i>genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank.
BMJ Open,
14(3), e081926-e081926.
Abstract.
Casanova F, Tian Q, Atkins JL, Wood AR, Williamson D, Qian Y, Zweibaum D, Ding J, Melzer D, Ferrucci L, et al (2024). Iron and risk of dementia: Mendelian randomisation analysis in UK Biobank.
Journal of Medical Genetics Abstract.
Tian Q, Zweibaum DA, Pilling LC, Casanova F, Qian Y, Atkins JL, Melzer D, Ding J, Ferrucci L (2024). Is Mitochondrial DNA Copy Number from Human Blood Associated with Iron Deposits in the Brain?.
Antioxid Redox Signal Abstract.
Author URL.
Banfield LR, Knapp KM, Pilling LC, Melzer D, Atkins JL (2023). Hemochromatosis Genetic Variants and Musculoskeletal Outcomes: 11.5‐Year Follow‐Up in the <scp>UK</scp> Biobank Cohort Study.
JBMR Plus,
7(10).
Abstract.
Atkins JL, Lucas MR, Pilling LC, Melzer D (2023). Letter to the editor regarding: “A haemochromatosis-causing HFE mutation is associated with SARS-CoV-2 susceptibility in the Czech population” clinica chimica acta 538 (2023) 211–215. Clinica Chimica Acta, 542, 117271-117271.
Tian Q, Zweibaum D, Qian Y, Pilling L, Casanova F, Atkins JL, Melzer D, Ding J, Ferrucci L (2023). Mitochondrial DNA copy number predicts dementia risk with early mobility impairment. Alzheimer's & Dementia, 19(S12).
Wannamethee SG, Atkins JL (2023). Sarcopenic Obesity and Cardiometabolic Health and Mortality in Older Adults: a Growing Health Concern in an Ageing Population.
Curr Diab Rep,
23(11), 307-314.
Abstract.
Author URL.
Kuo C-L, Pilling LC, Atkins JL, Fortinsky RH, Kuchel GA, Melzer D (2022). APOE e4 Genotypes Increase Risk of Delirium During COVID-19-Related Hospitalizations: Evidence from a Large UK Cohort.
J Gerontol a Biol Sci Med Sci,
77(4), 879-880.
Author URL.
Pilling LC, Atkins JL, Melzer D (2022). Genetic modifiers of penetrance to liver endpoints in HFE hemochromatosis: Associations in a large community cohort.
Hepatology,
76(6), 1735-1745.
Abstract.
Author URL.
Atkins JL, Jylhävä J, Pedersen NL, Magnusson PK, Lu Y, Wang Y, Hägg S, Melzer D, Williams DM, Pilling LC, et al (2021). A genome-wide association study of the frailty index highlights brain pathways in ageing.
Aging Cell,
20(9).
Abstract.
Author URL.
Pilling LC, Turkmen D, Fullalove H, Atkins JL, Delgado J, Kuo C-L, Kuchel GA, Ferrucci L, Bowden J, Masoli JAH, et al (2021). Analysis of <i>CYP2C19</i> genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study.
BMJ OPEN,
11(12).
Author URL.
Kuo C-L, Pilling LC, Atkins JL, Masoli JAH, Delgado J, Tignanelli C, Kuchel GA, Melzer D, Beckman KB, Levine ME, et al (2021). Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants.
The Journals of Gerontology: Series A,
76(8), e133-e141.
Abstract.
Kuo C-L, Pilling LC, Liu Z, Atkins JL, Levine ME (2021). Genetic associations for two biological age measures point to distinct aging phenotypes.
Aging Cell,
20(6).
Abstract.
Author URL.
Pilling LC, Türkmen D, Fullalove H, Atkins JL, Delgado J, Kuo C-L, Kuchel GA, Ferrucci L, Bowden J, Masoli JAH, et al (2021). Genetic variation in activating clopidogrel: longer-term outcomes in a large community cohort.
Abstract.
Jones G, Trajanoska K, Santanasto AJ, Stringa N, Kuo C-L, Atkins JL, Lewis JR, Duong T, Hong S, Biggs ML, et al (2021). Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
Nature Communications,
12(1).
Abstract.
Atkins JL, Pilling LC, Heales CJ, Savage S, Kuo C-L, Kuchel GA, Steffens DC, Melzer D (2021). Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort.
Journal of Alzheimer's Disease,
79(3), 1203-1211.
Abstract.
Lochlainn MN, Cox NJ, Wilson T, Hayhoe RPG, Ramsay SE, Granic A, Isanejad M, Roberts HC, Wilson D, Welch C, et al (2021). Nutrition and frailty: Opportunities for prevention and treatment.
Nutrients,
13(7).
Abstract.
Kuo C-L, Pilling LC, Atkins JL, Kuchel GA, Melzer D (2020). <i>ApoE</i> e2 and aging-related outcomes in 379,000 UK Biobank participants.
Abstract.
Kuo C-L, Pilling LC, Atkins JL, Masoli JAH, Delgado J, Kuchel GA, Melzer D (2020). APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort.
J Gerontol a Biol Sci Med Sci,
75(11), 2231-2232.
Author URL.
Kuo C-L, Pilling LC, Atkins JL, Masoli JAH, Delgado J, Kuchel GA, Melzer D (2020). ApoE e4e4 Genotype and Mortality with COVID-19 in UK Biobank. The Journals of Gerontology: Series A, 75(9), 1801-1803.
Atkins JL, Pilling LC, Masoli JAH, Kuo C-L, Shearman JD, Adams PC, Melzer D (2020). Association of Hemochromatosis <i>HFE</i> p.C282Y Homozygosity with Hepatic Malignancy. JAMA, 324(20), 2048-2048.
Pilling LC, Jones LC, Masoli JAH, Delgado J, Atkins JL, Bowden J, Fortinsky RH, Kuchel GA, Melzer D (2020). Low Vitamin D Levels and Risk of Incident Delirium in 351,000 Older <scp>UK</scp> Biobank Participants.
Journal of the American Geriatrics Society,
69(2), 365-372.
Abstract.
Atkins JL, Wannamathee SG (2020). Sarcopenic obesity in ageing: cardiovascular outcomes and mortality.
British Journal of Nutrition,
124(10), 1102-1113.
Abstract.
Tian Q, Pilling LC, Atkins JL, Melzer D, Ferrucci L (2020). The relationship of parental longevity with the aging brain—results from UK Biobank.
GeroScience,
42(5), 1377-1385.
Abstract.
Parsons TJ, Papachristou E, Atkins JL, Papacosta O, Ash S, Lennon LT, Whincup PH, Ramsay SE, Wannamethee SG (2019). Healthier diet quality and dietary patterns are associated with lower risk of mobility limitation in older men.
Eur J Nutr,
58(6), 2335-2343.
Abstract.
Author URL.
Tamosauskaite J, Atkins J, Pilling L, Kuo C-L, Kuchel G, Ferrucci L, Melzer D (2019). Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants. Journals of Gerontology - Series a Biological Sciences and Medical Sciences
Atkins JL, Delgado J, Melzer D (2019). Life’s Simple 7 likely to be associated with dementia risk reduction in both midlife and older age groups. BMJ, l5491-l5491.
Parsons TJ, Papachristou E, Atkins JL, Papacosta O, Ash S, Lennon LT, Whincup PH, Ramsay SE, Wannamethee SG (2019). Physical frailty in older men: prospective associations with diet quality and patterns.
Age Ageing,
48(3), 355-360.
Abstract.
Author URL.
Atkins JL, Delgado J, Pilling L, Bowman K, Masoli J, Kuchel G, Ferrucci L, Melzer D (2018). Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence from 421,000 Participants in Two Cohorts. Journals of Gerontology: Medical Sciences
Pilling LC, Atkins JL, Kuchel GA, Ferrucci L, Melzer D (2018). Red cell distribution width and common disease onsets in 240,477 healthy volunteers followed for up to 9 years.
PLoS ONE,
13(9).
Abstract.
Bowman K, Atkins JL, Delgado J, Kos K, Kuchel GA, Ble A, Ferrucci L, Melzer D (2017). Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants.
Am J Clin Nutr,
106(1), 130-135.
Abstract.
Author URL.
Hawkesworth S, Silverwood RJ, Armstrong B, Pliakas T, Nanchahal K, Sartini C, Amuzu A, Wannamethee G, Atkins J, Ramsay SE, et al (2017). Investigating the importance of the local food environment for fruit and vegetable intake in older men and women in 20 UK towns: a cross-sectional analysis of two national cohorts using novel methods.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY,
14 Author URL.
Pilling LC, Atkins JL, Duff MO, Beaumont RN, Jones SE, Tyrrell J, Kuo C-L, Ruth KS, Tuke MA, Yaghootkar H, et al (2017). Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
PLoS One,
12(9).
Abstract.
Author URL.
Atkins JL, Whincup PH, Morris RW, Lennon LT, Papacosta O, Wannamethee SG (2016). Dietary patterns and the risk of CVD and all-cause mortality in older British men.
Br J Nutr,
116(7), 1246-1255.
Abstract.
Author URL.
Atkins JL, Pilling LC, Ble A, Dutta A, Harries LW, Murray A, Brayne C, Robine JM, Kuchel GA, Ferrucci L, et al (2016). Longer-Lived Parents and Cardiovascular Outcomes: 8-Year Follow-Up in 186,000 U.K. Biobank Participants. Journal of the American College of Cardiology, 68(8), 874-875.
Atkins JL, Ramsay SE, Whincup PH, Morris RW, Lennon LT, Wannamethee SG (2015). Diet quality in older age: the influence of childhood and adult socio-economic circumstances.
British Journal of Nutrition,
113(9), 1441-1452.
Abstract.
Wannamethee SG, Atkins JL (2015). Muscle loss and obesity: the health implications of sarcopenia and sarcopenic obesity.
Proceedings of the Nutrition Society,
74(4), 405-412.
Abstract.
Atkins JL, Wannamethee SG (2015). The effect of sarcopenic obesity on cardiovascular disease and all-cause mortality in older people.
Reviews in Clinical Gerontology,
25(2), 86-97.
Abstract.
Atkins JL, Whincup PH, Morris RW, Lennon LT, Papacosta O, Wannamethee SG (2014). High Diet Quality is Associated with a Lower Risk of Cardiovascular Disease and All-Cause Mortality in Older Men. The Journal of Nutrition, 144(5), 673-680.
Atkins JL, Whincup PH, Morris RW, Wannamethee SG (2014). Low muscle mass in older men: the role of lifestyle, diet and cardiovascular risk factors. The Journal of nutrition, health and aging, 18(1), 26-33.
Atkins JL, Whincup PH, Morris RW, Wannamethee SG (2014). Response to Safer et al. Journal of the American Geriatrics Society, 62(6), 1208-1209.
Atkins JL, Whincup PH, Morris RW, Lennon LT, Papacosta O, Wannamethee SG (2014). Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: a Population‐Based Cohort Study of Older Men.
Journal of the American Geriatrics Society,
62(2), 253-260.
Abstract.
Woodhall SC, Atkins JL, Soldan K, Hughes G, Bone A, Gill ON (2012). Repeat genital<i>Chlamydia trachomatis</i>testing rates in young adults in England, 2010. Sexually Transmitted Infections, 89(1), 51-56.
Nicolaou N, Shane S, Cherkas L, Hunkin J, Spector TD (2008). Is the Tendency to Engage in Entrepreneurship Genetic?.
Management Science,
54(1), 167-179.
Abstract.
Kimura M, Cherkas LF, Kato BS, Demissie S, Hjelmborg JB, Brimacombe M, Cupples A, Hunkin JL, Gardner JP, Lu X, et al (2008). Offspring's Leukocyte Telomere Length, Paternal Age, and Telomere Elongation in Sperm. PLoS Genetics, 4(2), e37-e37.
Cherkas LF (2008). The Association Between Physical Activity in Leisure Time and Leukocyte Telomere Length. Archives of Internal Medicine, 168(2), 154-154.
Stubbe JH, Boomsma DI, Vink JM, Cornes BK, Martin NG, Skytthe A, Kyvik KO, Rose RJ, Kujala UM, Kaprio J, et al (2006). Genetic Influences on Exercise Participation in 37.051 Twin Pairs from Seven Countries. PLoS ONE, 1(1), e22-e22.
Paul SN, Kato BS, Hunkin JL, Vivekanandan S, Spector TD, Fields KB (2006). The Big Finger: the second to fourth digit ratio is a predictor of sporting ability in women. Commentary. British Journal of Sports Medicine, 40(12), 981-983.
Cherkas LF, Aviv A, Valdes AM, Hunkin JL, Gardner JP, Surdulescu GL, Kimura M, Spector TD (2006). The effects of social status on biological aging as measured by white‐blood‐cell telomere length.
Aging Cell,
5(5), 361-365.
Abstract.
Conferences
Atkins JL, Pilling LC, Heales CJ, Savage S, Kuo C-L, Kuchel GA, Steffens DC, Melzer D (2022). Hereditary haemochromatosis mutations, brain iron imaging and dementia risk in the UK Biobank cohort.
Author URL.
Atkins JL, Pilling LC, Melzer D (2022). OP56 Hereditary haemochromatosis: genetic iron overload – a missed opportunity for diagnosis and treatment. SSM Annual Scientific Meeting.
Kuo C-L, Pilling L, Atkins J, Masoli J, Delgado J, Kuchel G, Melzer D, Levine M (2021). Antipsychotic Prescribing in VA-Contracted Community Nursing Homes and Incident Use Among Veterans.
Masoli J, Atkins J, Delgado J, Pilling L, Melzer D (2021). BEING NON-FRAIL AND FREE FROM CARDIOVASCULAR DISEASE REDUCES COVID-19 RISK IN 269,164 OLDER UK BIOBANK PARTICIPANTS.
Author URL.
Kuo C-L, Pilling L, Atkins J, Masoli J, Delgado J, Kuchel G, Melzer D, Levine M (2021). BIOLOGICAL AGING PREDICTS VULNERABILITY TO COVID-19 SEVERITY IN UK BIOBANK PARTICIPANTS.
Author URL.
Kuo C-L, Pilling L, Atkins J, Masoli J, Delgado J, Kuchel G, Melzer D, Levine M (2021). Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants.
Masoli J, Kuo CL, Atkins J, Pilling L, Delgado J, Kuchel G, Melzer D (2021). DEMENTIA, ApoE AND COVID-19 SEVERITY.
Author URL.
Atkins J, Masoli J, Delgado J, Pilling L, Kuo C-L, Kuchel G, Melzer D (2021). Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort.
Atkins J, Pilling LC, Williams D, Jylhävä J, Melzer D (2019). CAUSES OF FRAILTY: GENETIC ANALYSIS IN 164,000 UK BIOBANK PARTICIPANTS.
Jylhava J, Pilling L, Williams D, Lu Y, Pedersen NL, Melzer D, Atkins J (2019). Genome-wide association study of a frailty Index in UK Biobank and TwinGene.
Author URL.
Atkins J, Pilling L, Melzer D (2019). OP37: HEREDITARY HAEMOCHROMATOSIS: ASSOCIATIONS
WITH MORBIDITY AND IRON SUPPLEMENT USE IN
451,243 UK BIOBANK PARTICIPANTS. Society for Social Medicine & Population Health and International Epidemiology Association European Congress Joint Annual Scientific Meeting. 4th - 6th Sep 2019.
Atkins JL, Delgado J, Pilling LC, Bowman K, Masoli JAH, Kuchel GA, Ferrucci L, Melzer D (2018). #IDEAL CARDIOVASCULAR RISK PROFILES AND AGEING: EVIDENCE FROM 421,000 OLDER PERSONS IN TWO COHORTS.
Author URL.
Melzer D, Pilling L, Atkins J, Tamosauskaite J (2018). IRON OVERLOAD AS a TREATABLE CAUSE OF FRAILTY: GENETIC EVIDENCE IN 200,000 SUBJECTS.
Atkins J, Pilling LC, Melzer D, Bowman K (2017). CAN GENETICS CLARIFY THE RISK PARADOXES OF LATER LIFE?.
Parsons TJ, Papachristou E, Ramsay SE, Atkins JL, Papacosta O, Lennon LT, Ash S, Whincup PH, Wannamethee SG (2017). DIET QUALITY, SARCOPENIA AND FRAILTY IN OLDER MEN: CROSS SECTIONAL ANALYSIS FROM THE BRITISH REGIONAL HEART STUDY.
Author URL.
Pilling LC, Atkins J, Melzer D (2017). GENETIC VARIANTS FOR AGING WELL SUGGEST POTENTIAL FOR INTERVENTION.
Atkins J, Pilling L, Ble A, Dutta A, Harries L, Murray A, Brayne C, Robine J, Kuchel G, Ferrucci L, et al (2016). OP82 Long-lived parents and cardiovascular outcomes: 8 year follow-up in 189,000 UK Biobank participants.
Atkins JL, Whincup PH, Morris RW, Lennon LT, Papacosta P, Wannamethee SG (2015). Abstract P049: Principal Component Analysis of Dietary Patterns and the Risk of Cardiovascular Disease and Mortality in Older British Men.
Atkins JL, Whincup PH, Morris RW, Lennon LT, Papacosta O, Wannamethee SG (2013). Dietary patterns and the risk of cardiovascular disease and mortality: a population-based cohort study of older British men.
Atkins JL, Whincup PH, Morris RW, Wannamethee SG (2013). Dietary patterns in older British men: the influence of early life social circumstances and area of residence.
Atkins JL, Whincup PH, Morris RW, Wannamethee SG (2013). OP86 Dietary Patterns in Older Men: Influence of Early Life Social Circumstances and Area of Residence.
Atkins JL, Whincup PH, Morris RW, Wannamethee SG (2013). T1: P.039 Sarcopenic obesity and the risk of cardiovascular disease and mortality: a population-based cohort study of older men.
Atkins JL, Whincup PH, Morris RW, Wannamethee SG (2013). T2: P.057 Dietary patterns in the elderly: Influence of early life social circumstances and area of residence.
Atkins JL, Whincup PH, Morris RW, Wannamethee SG (2012). PS38 Sarcopenic Obesity and Risk of All-Cause and Cardiovascular Mortality in Older Men.
Cherkas L, Harris J, Hunkin J, Kato B, Zhang G, Valdes A, Aviv A, Spector TD, Atkins JL (2007). Twins, telomeres and aging.