Loading content
Dr Francesco Casanova

Dr Francesco Casanova

Associate Research Fellow

+44 (0) 1392 403081

Diabetes and Vascular Research Centre 

Francesco Casanova obtained his PhD in Exercise Physiology from Bangor University and in 2010 joined the Diabetes & Vascular Medicine Research Centre led by Professor Angela Shore. He has been working as an Associate Research Fellow on the SUMMIT project (http://www.imi-summit.eu/), an IMI funded project with 29 partners. Francesco's interest is in vascular physiology in clinical populations with an expertise in microvascular dysfunction.

Recently Dr Casanova has been working with Professor Timothy Frayling focusing on using genome wide approaches to identify genetic variation associated with common human disease affecting the microcirculation.
 

Qualifications

PhD

BSc

AFHEA

Research

Research projects

Surrogate markers for Micro- and Macro-vascular hard endpoints for Innovative diabetes Tools (SUMMIT-IMI). An IMI funded project with 29 partners. The vascular work package in collaboration with Lund, Pisa, Dundee and Florence explores novel techniques to assess plaque structure, microvascular function and assess the use of optical coherence tomography to detect early changes in retinal thickness in patients with diabetes with and without cardiovascular disease.
 

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2017). Brachial artery vasodilatory response and wall shear rate determined by multi-gate Doppler in a healthy young cohort. J Appl Physiol (1985) Abstract.  Author URL.
Casanova F, Adingupu DD, Adams F, Gooding KM, Looker HC, Aizawa K, Dove F, Elyas S, Belch JJF, Gates PE, et al (2017). The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control. Cardiovasc Diabetol, 16(1). Abstract.  Author URL.
Gonçalves I, Edsfeldt A, Colhoun HM, Shore AC, Palombo C, Natali A, Fredrikson GN, Björkbacka H, Wigren M, Bengtsson E, et al (2016). Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. BMC Cardiovasc Disord, 16(1). Abstract.  Author URL.  Full text.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Shore AC, Strain WD, Gates PE (2016). Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. Ultrasound Med Biol, 42(5), 1130-1137. Abstract.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Strain WD, Shore AC, Gates PE (2016). Reactivity to low-flow as a potential determinant for brachial artery flow-mediated vasodilatation. Physiol Rep, 4(12). Abstract.  Author URL.  Full text.
Bokori-Brown M, Petrov PG, Khafaji MA, Mughal MK, Naylor CE, Shore AC, Gooding KM, Casanova F, Mitchell TJ, Titball RW, et al (2016). Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES. J Biol Chem, 291(19), 10210-10227. Abstract.  Author URL.  Full text.
Meertens RM, Knapp KM, Strain WD, Casanova F (2016). The Effects of Lumbar Sympathectomy on Bone and Soft Tissue Haemodynamics of the Leg recorded using Near Infrared Spectroscopy: a Case Report. Journal of Biomedical Engineering and Informatics, 3, 28-32. Full text.
Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW, et al (2015). Blood Oxygen Saturation After Ischemia is Altered with Abnormal Microvascular Reperfusion. Microcirculation, 22(4), 294-305. Abstract.  Author URL.
Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, et al (2015). Elevated Plasma Levels of MMP-12 Are Associated with Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects with Type 2 Diabetes. Arterioscler Thromb Vasc Biol, 35(7), 1723-1731. Abstract.  Author URL.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. Journal of Internal Medicine, 278(3), 291-302. Abstract.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. J Intern Med, 278(3), 291-302. Abstract.  Author URL.
Clark C, Casanova F, Gooding K, Pamphilon N, Aizawa K, Mawson D, Adingupu D, Ball C, Worthington F, Elyas S, et al (2014). Inter-arm blood pressure difference and differences in arterial stiffness. JOURNAL OF HUMAN HYPERTENSION, 28(10), 626-627. Author URL.
Cooney JK, Moore JP, Ahmad YA, Jones JG, Lemmey AB, Casanova F, Maddison PJ, Thom JM (2013). A simple step test to estimate cardio-respiratory fitness levels of rheumatoid arthritis patients in a clinical setting. Int J Rheumatol, 2013 Abstract.  Author URL.
Adingupu DD, Elyas S, Casanova F, Gates PE, Shore AC, Strain WD (2013). Microvascular autoregulatory response to ischaemia and pulse pressure. JOURNAL OF HUMAN HYPERTENSION, 27(10), 652-653. Author URL.
Adingupu DD, Thorn C, Casanova F, Elyas S, Gates PE, Strain WD, Shore AC (2013). Microvascular autoregulatory response to ischaemia in the skin and association with mean blood oxygen saturation. JOURNAL OF HUMAN HYPERTENSION, 27(10), 640-641. Author URL.
Lemmey AB, Marcora SM, Chester K, Wilson S, Casanova F, Maddison PJ (2009). Effects of high-intensity resistance training in patients with rheumatoid arthritis: a randomized controlled trial. Arthritis Rheum, 61(12), 1726-1734. Abstract.  Author URL.
Marcora SM, Casanova F, Fortes MB, Maddison PJ (2007). Validity and reliability of the Siconolfi Step Test for assessment of physical fitness in patients with systemic lupus erythematosus. Arthritis Rheum, 57(6), 1007-1011. Abstract.  Author URL.
Marcora S, Casanova F, Williams E, Jones J, Elamanchi R, Lemmey A (2006). Preliminary evidence for cachexia in patients with well-established ankylosing spondylitis. Rheumatology (Oxford), 45(11), 1385-1388. Abstract.  Author URL.
La Torre A, Impellizzeri FM, Rampinini E, Casanova F, Alberti G, Marcora SM (2005). Cardiovascular responses to aerobic step dance sessions with and without appendicular overload. J Sports Med Phys Fitness, 45(3), 264-269. Abstract.  Author URL.

Conferences

Casanova F, Adingupu DD, Gooding KM, Aizawa K, Gates PE, Elyas S, Shore AC, Strain DW (2017). Association Between Renal Function and Matrix Metalloproteinases in Type 2 Diabetes.  Author URL.
Gooding K, Shore AC, Casanova F, Colhoun HM, Looker HC, Leese GP, Agardh E (2017). EXAMINING LONGITUDINAL CHANGES OF MACULAR THICKNESS IN THE EARLY STAGES OF DIABETIC RETINOPATHY.  Author URL.
Gooding K, Mayne T, Casanova F, Ball C, Cox D, Ling R, Shore A (2017). Exploring the Relationship Between Retinal Micro-aneurysms with Plasma Levels of Matrix Metal-loproteinases and Growth Factors in Type 2 Diabetes.  Author URL.
Meertens R, Knapp K, Strain D, Casanova F (2016). NEAR INFRARED SPECTROSCOPY: a POTENTIAL TOOL FOR ASSESSING HAEMODYNAMIC MARKERS OF THE MICROVASCULAR BLOOD SUPPLY WITHIN BONE TISSUE.  Author URL.  Full text.
Meertens RM, Knapp KM, Strain WD, Casanova F (2016). The use of near infrared spectroscopy (NIRS) as a diagnostic tool to measure microvascular haemodynamics in bone tissue. National Osteoporosis Society 2016. 7th - 9th Nov 2016. Full text.
Casanova F, Adingupu D, Gooding K, Strain D, Shore A (2015). DOES GLYCAEMIC CONTROL AFFECT MICROVASCULAR FUNCTION INDEPENDENT OF BLOOD PRESSURE IN TYPE 2 DIABETES?.  Author URL.
Gooding KM, Shore AC, Ling R, Casanova F, Looker HC, Agardh E (2015). Regional differences in macular thickness in the early stages of diabetic retinopathy in type 2 diabetes.  Author URL.
Chapman DP, Gooding KM, McDonald TJ, Anning CM, Pamphilon N, Ball C, Casanova F, Shore AC (2015). Using clinical characteristics to account for variation of urinary creatinine excretion improves the accuracy of the albumin to creatinine ratio (ACR) to identify individuals with microalbuminuria.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Mawson DM, Shore AC, Strain WD, Gates PE (2013). Carotid artery intima-media echogenicity and aortic stiffness in healthy middle-aged and older humans.  Author URL.

Publications by year


2017

Casanova F, Adingupu DD, Gooding KM, Aizawa K, Gates PE, Elyas S, Shore AC, Strain DW (2017). Association Between Renal Function and Matrix Metalloproteinases in Type 2 Diabetes.  Author URL.
Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2017). Brachial artery vasodilatory response and wall shear rate determined by multi-gate Doppler in a healthy young cohort. J Appl Physiol (1985) Abstract.  Author URL.
Gooding K, Shore AC, Casanova F, Colhoun HM, Looker HC, Leese GP, Agardh E (2017). EXAMINING LONGITUDINAL CHANGES OF MACULAR THICKNESS IN THE EARLY STAGES OF DIABETIC RETINOPATHY.  Author URL.
Gooding K, Mayne T, Casanova F, Ball C, Cox D, Ling R, Shore A (2017). Exploring the Relationship Between Retinal Micro-aneurysms with Plasma Levels of Matrix Metal-loproteinases and Growth Factors in Type 2 Diabetes.  Author URL.
Casanova F, Adingupu DD, Adams F, Gooding KM, Looker HC, Aizawa K, Dove F, Elyas S, Belch JJF, Gates PE, et al (2017). The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control. Cardiovasc Diabetol, 16(1). Abstract.  Author URL.

2016

Gonçalves I, Edsfeldt A, Colhoun HM, Shore AC, Palombo C, Natali A, Fredrikson GN, Björkbacka H, Wigren M, Bengtsson E, et al (2016). Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. BMC Cardiovasc Disord, 16(1). Abstract.  Author URL.  Full text.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Shore AC, Strain WD, Gates PE (2016). Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. Ultrasound Med Biol, 42(5), 1130-1137. Abstract.  Author URL.
Meertens R, Knapp K, Strain D, Casanova F (2016). NEAR INFRARED SPECTROSCOPY: a POTENTIAL TOOL FOR ASSESSING HAEMODYNAMIC MARKERS OF THE MICROVASCULAR BLOOD SUPPLY WITHIN BONE TISSUE.  Author URL.  Full text.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Strain WD, Shore AC, Gates PE (2016). Reactivity to low-flow as a potential determinant for brachial artery flow-mediated vasodilatation. Physiol Rep, 4(12). Abstract.  Author URL.  Full text.
Bokori-Brown M, Petrov PG, Khafaji MA, Mughal MK, Naylor CE, Shore AC, Gooding KM, Casanova F, Mitchell TJ, Titball RW, et al (2016). Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES. J Biol Chem, 291(19), 10210-10227. Abstract.  Author URL.  Full text.
Meertens RM, Knapp KM, Strain WD, Casanova F (2016). The Effects of Lumbar Sympathectomy on Bone and Soft Tissue Haemodynamics of the Leg recorded using Near Infrared Spectroscopy: a Case Report. Journal of Biomedical Engineering and Informatics, 3, 28-32. Full text.
Meertens RM, Knapp KM, Strain WD, Casanova F (2016). The use of near infrared spectroscopy (NIRS) as a diagnostic tool to measure microvascular haemodynamics in bone tissue. National Osteoporosis Society 2016. 7th - 9th Nov 2016. Full text.

2015

Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW, et al (2015). Blood Oxygen Saturation After Ischemia is Altered with Abnormal Microvascular Reperfusion. Microcirculation, 22(4), 294-305. Abstract.  Author URL.
Casanova F, Adingupu D, Gooding K, Strain D, Shore A (2015). DOES GLYCAEMIC CONTROL AFFECT MICROVASCULAR FUNCTION INDEPENDENT OF BLOOD PRESSURE IN TYPE 2 DIABETES?.  Author URL.
Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, et al (2015). Elevated Plasma Levels of MMP-12 Are Associated with Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects with Type 2 Diabetes. Arterioscler Thromb Vasc Biol, 35(7), 1723-1731. Abstract.  Author URL.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. Journal of Internal Medicine, 278(3), 291-302. Abstract.
Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. J Intern Med, 278(3), 291-302. Abstract.  Author URL.
Gooding KM, Shore AC, Ling R, Casanova F, Looker HC, Agardh E (2015). Regional differences in macular thickness in the early stages of diabetic retinopathy in type 2 diabetes.  Author URL.
Chapman DP, Gooding KM, McDonald TJ, Anning CM, Pamphilon N, Ball C, Casanova F, Shore AC (2015). Using clinical characteristics to account for variation of urinary creatinine excretion improves the accuracy of the albumin to creatinine ratio (ACR) to identify individuals with microalbuminuria.  Author URL.

2014

Clark C, Casanova F, Gooding K, Pamphilon N, Aizawa K, Mawson D, Adingupu D, Ball C, Worthington F, Elyas S, et al (2014). Inter-arm blood pressure difference and differences in arterial stiffness. JOURNAL OF HUMAN HYPERTENSION, 28(10), 626-627. Author URL.

2013

Cooney JK, Moore JP, Ahmad YA, Jones JG, Lemmey AB, Casanova F, Maddison PJ, Thom JM (2013). A simple step test to estimate cardio-respiratory fitness levels of rheumatoid arthritis patients in a clinical setting. Int J Rheumatol, 2013 Abstract.  Author URL.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Mawson DM, Shore AC, Strain WD, Gates PE (2013). Carotid artery intima-media echogenicity and aortic stiffness in healthy middle-aged and older humans.  Author URL.
Lemmey Andrew B. Elamanchi Srinivasa Rao , Marcora. Samuele M. Casanova Francesco and Maddison Peter J. (2013). Efficacy of Nandrolone Decanoate in Treating Rheumatoid Cachexia in Male Rheumatoid Arthritis Patients, Innovative Rheumatology.  Author URL.
Adingupu DD, Elyas S, Casanova F, Gates PE, Shore AC, Strain WD (2013). Microvascular autoregulatory response to ischaemia and pulse pressure. JOURNAL OF HUMAN HYPERTENSION, 27(10), 652-653. Author URL.
Adingupu DD, Thorn C, Casanova F, Elyas S, Gates PE, Strain WD, Shore AC (2013). Microvascular autoregulatory response to ischaemia in the skin and association with mean blood oxygen saturation. JOURNAL OF HUMAN HYPERTENSION, 27(10), 640-641. Author URL.

2009

Lemmey AB, Marcora SM, Chester K, Wilson S, Casanova F, Maddison PJ (2009). Effects of high-intensity resistance training in patients with rheumatoid arthritis: a randomized controlled trial. Arthritis Rheum, 61(12), 1726-1734. Abstract.  Author URL.

2007

Marcora SM, Casanova F, Fortes MB, Maddison PJ (2007). Validity and reliability of the Siconolfi Step Test for assessment of physical fitness in patients with systemic lupus erythematosus. Arthritis Rheum, 57(6), 1007-1011. Abstract.  Author URL.

2006

Marcora S, Casanova F, Williams E, Jones J, Elamanchi R, Lemmey A (2006). Preliminary evidence for cachexia in patients with well-established ankylosing spondylitis. Rheumatology (Oxford), 45(11), 1385-1388. Abstract.  Author URL.

2005

La Torre A, Impellizzeri FM, Rampinini E, Casanova F, Alberti G, Marcora SM (2005). Cardiovascular responses to aerobic step dance sessions with and without appendicular overload. J Sports Med Phys Fitness, 45(3), 264-269. Abstract.  Author URL.

Back | Edit Profile