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University of Exeter Medical School

Dr Fiona Warren

Dr Fiona Warren

Senior Lecturer in Medical Statistics

 f.c.warren@exeter.ac.uk

 2749

 +44 (0) 1392 722749

 Smeall building 

 

Smeall Building, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK


Overview

 I am based in the Primary Care Department in the Smeall Building at St Luke's Campus. My main areas of interest include clinical trials and meta-analysis/evidence synthesis, in particular the use of individual participant data within meta-analysis. Completed clinical trials include the ESTEEM trial, based in primary care, evaluating the effects on patient experience, and primary care workload, of two telephone triage interventions for patients requesting a same-day GP consultation, one led by GPs, the other by nurses.  Other completed trials include the REACH-HF trial, which evaluated the effects of an intervention for patients with heart failure, and potentially their caregivers as well, aimed at improving quality of life, and the CADENCE trial, which is based around the provision of psychological care for patients receiving cardiac rehabilitation. Current trials include the ERICA trial, which aims to improve diagnosis of cancer in primary care by making an electronic diagnostic tool (known as an eRAT) available to GPs, and the EcoWeb trial, part of an international collaboration that aims to promote mental health in young adults. 

A recent project has involved an international collaboration of psychologists with an interest in mindfulness based cognitive therapy (MBCT); this collaboration pooled individual participant data from several trials conducted in Europe and North America, with the aim of comparing the effects of MBCT with other forms of treatment for patients currently in remission of depression. Two other projects involving individual participant data are ongoing, one involving the investigation of inter-arm difference in blood pressure as a potential prognostic marker for cardiovascular disease (InterPress), and the other examining the effects of exercise rehabilitation for patients with heart failure (ExTraMATCH II).

I have also been involved in large scale surveys within primary care, including an analysis of patients' experience of out-of-hours primary care services, reported within the General Practice Patient Survey (GPPS).

Career

Following a first degree in Medicine, I acquired experience in clinical practice and research (formerly working for the MRC Institute for Environment and Health). I then completed a Master's degree in Medical Statistics at the University of Leicester, which was followed by a PhD in evidence synthesis and meta-analysis methods, specifically focusing on the application of appropriate methods for meta-analysis of adverse events data. In October 2010, I moved to Exeter to take on a role primarily focusing on clinical trials, whilst maintaining my interests in evidence synthesis and meta-analysis.

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Publications

Journal articles

Lang C, Smith K, Wingham J, Eyre V, Greaves CJ, Warren FC, Green C, Jolly K, Davis RC, Doherty P, et al (In Press). A Randomised Controlled Trial of a Facilitated Home-Based Rehabilitation Intervention in Patients with Heart Failure with Preserved Ejection Fraction and their Caregivers: REACH-HFpEF Pilot Study. BMJ Open
Breedvelt JJF, Karyotaki E, Warren FC, Brouwer ME, Jermann F, Hollandare F, Klein N, de Jonge M, Klein DN, Farb N, et al (In Press). An Individual Participant Data meta-analysis of psychological interventions for preventing depressive relapse. nature mental health
Wingham J, Frost J, Britten N, Greaves C, Abraham C, Warren F, Jolly K, Miles J, Paul K, Doherty P, et al (In Press). Caregiver outcomes of the REACH-HF multicentre randomized controlled trial of home-based rehabilitation for heart failure with reduced ejection fraction. European Journal of Cardiovascular Nursing
Richards DA, Bollen J, Jones B, Melendez-Torres GJ, Hulme C, Cockcroft E, Cook H, Cooper J, Creanor S, Cruickshank S, et al (In Press). Evaluation of a COVID-19 Fundamental Nursing Care Guideline (COVID-NURSE) Versus Usual Care: a Cluster Randomised Controlled Trial.
Byng R, Kirkpatrick T, Lennox C, Warren FC, Anderson R, Brand SL, Callaghan L, Carroll L, Durcan G, Gill L, et al (In Press). Evaluation of a complex intervention for prisoners with common mental health problems, near to and after release: the Engager randomised controlled trial. British Journal of Psychiatry Abstract.
Bottcher L, Breedvelt J, Warren F, Segal Z, Kuyken W, Bockting C (In Press). Identifying Relapse Predictors in Individual Participant Data with Decision Trees. BMC Psychiatry
Thompson TP, Warren FC, Greaves CJ, Aveyard P, Ayres R, Byng R, Taylor RS, Campbell JL, Ussher M, Michie S, et al (In Press). Lessons learned from recruiting socioeconomically disadvantaged smokers into a pilot randomized controlled trial to explore the role of Exercise Assisted Reduction then Stop (EARS) smoking.
O'Mahen HA, Richards DR, Woodford J, Wilkinson E, McGinley J, Taylor R, Warren F (In Press). Netmums: a Phase II Randomized Controlled Trial of a Guided Internet Behavioral Activation Treatment for Postpartum Depression. Psychological Medicine, in press Abstract.
Eyre V, Lang C, Smith S, Jolly C, Wingham J, Abraham C, Green C, Warren F, Britten N, Greaves C, et al (In Press). Rehabilitation Enablement in Chronic Heart Failure-a facilitated self-care rehabilitation intervention in patients with heart failure with preserved ejection fraction (REACH-HFpEF) and their caregivers: Rationale and protocol for a single centre pilot randomised controlled trial (Protocol). BMJ Open
Tarrant M, Carter M, Dean S, Taylor R, Warren F, Spencer A, Adamson J, Landa P, Code C, Calitri RA, et al (In Press). Singing for People with Aphasia (SPA): a Protocol for a Pilot Randomised Controlled Trial of a Group Singing Intervention to Improve Wellbeing. BMJ Open
Haasova M, Warren F, Thompson T, Ussher M, Taylor A (In Press). The association between habitual physical activity and cigarette cravings, and influence of smokers’ characteristics in disadvantaged smokers not ready to quit. Psychopharmacology
Dalal HM, Taylor RS, Jolly K, Davis RC, Doherty P, Miles J, Van Lingen R, Warren F, Green C, Wingham J, et al (In Press). The effects and costs of home-based rehabilitation for heart failure with reduced ejection fraction: the REACH-HF multicentre randomized controlled trial. European Journal of Preventive Cardiology
Barnhofer T, Dunn BD, Strauss C, Ruths F, Barrett B, Ryan M, Ladwa A, Stafford F, Fichera R, Baber H, et al (2023). A randomised controlled trial to investigate the clinical effectiveness and cost effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) for depressed non-responders to Increasing Access to Psychological Therapies (IAPT) high-intensity therapies: study protocol. Trials, 24(1). Abstract.  Author URL.
Richards DA, Bollen J, Jones B, Melendez-Torres GJ, Hulme C, Cockcroft E, Cook H, Cooper J, Creanor S, Cruickshank S, et al (2023). Evaluation of a COVID-19 fundamental nursing care guideline versus usual care: the COVID-NURSE cluster randomized controlled trial. J Adv Nurs Abstract.  Author URL.
Kansal A, Duarte R, Copley S, Warren FC, Taylor RS, Eldabe S (2023). Systematic Review to Identify Predictors of Treatment Response to Neuromodulation in Patients with Neuropathic Pain-Protocol. Neuromodulation, 26(8), 1493-1498. Abstract.  Author URL.
McDonagh S, Sheppard J, Warren F, Boddy K, Farmer L, Shore H, Williams P, Lewis P, Fordham AJ, Martin U, et al (2022). ARM BASED ON LEG BLOOD PRESSURES (ABLE-BP): CAN SYSTOLIC LEG BLOOD PRESSURE MEASUREMENTS PREDICT BRACHIAL BLOOD PRESSURE? AN INDIVIDUAL PARTICIPANT DATA META-ANALYSIS. Journal of Hypertension, 40(Suppl 1), e8-e9.
Grabski M, McAndrew A, Lawn W, Marsh B, Raymen L, Stevens T, Hardy L, Warren F, Bloomfield M, Borissova A, et al (2022). Adjunctive Ketamine with Relapse Prevention-Based Psychological Therapy in the Treatment of Alcohol Use Disorder. Am J Psychiatry, 179(2), 152-162. Abstract.  Author URL.
Byng R, Lennox C, Kirkpatrick T, Quinn C, Anderson R, Brand SL, Callaghan L, Carroll L, Durcan G, Gill L, et al (2022). Development and evaluation of a collaborative care intervention for male prison leavers with mental health problems: the Engager research programme. Programme Grants for Applied Research, 10(8), 1-46. Abstract.
Hunter RM, Anderson R, Kirkpatrick T, Lennox C, Warren F, Taylor RS, Shaw J, Haddad M, Stirzaker A, Maguire M, et al (2022). Economic evaluation of a complex intervention (Engager) for prisoners with common mental health problems, near to and after release: a cost-utility and cost-consequences analysis. Eur J Health Econ, 23(2), 193-210. Abstract.  Author URL.
Clark CE, Warren FC, Boddy K, McDonagh STJ, Moore SF, Teresa Alzamora M, Ramos Blanes R, Chuang S-Y, Criqui MH, Dahl M, et al (2022). Higher Arm Versus Lower Arm Systolic Blood Pressure and Cardiovascular Outcomes: a Meta-Analysis of Individual Participant Data from the INTERPRESS-IPD Collaboration. Hypertension, 79(10), 2328-2335. Abstract.  Author URL.
Dunn B (2022). How well do Cognitive Behavioural Therapy and Behavioural Activation for depression repair anhedonia? a secondary analysis of the COBRA randomised controlled trial. Behaviour Research and Therapy Abstract.
Shields BM, Dennis JM, Angwin CD, Warren F, Henley WE, Farmer AJ, Sattar N, Holman RR, Jones AG, Pearson ER, et al (2022). Patient stratification for determining optimal second-line and third-line therapy for type 2 diabetes: the TriMaster study. Nature Medicine, 29(2), 376-383.
McDonagh STJ, Rhodes S, Warren FC, Keenan S, Pentecost C, Keeling P, James M, Taylor RS, Clark CE (2022). Performance of the imPulse device for the detection of atrial fibrillation in hospital settings. Cardiovascular Digital Health Journal, 3(4), 171-178.
Russell G, Stapley S, Newlove-Delgado T, Salmon A, White R, Warren F, Pearson A, Ford T (2022). Time trends in autism diagnosis over 20 years: a UK population-based cohort study. J Child Psychol Psychiatry, 63(6), 674-682. Abstract.  Author URL.
Dalal H, Taylor R, Wingham J, Greaves C, Jolly K, Lang C, Davis R, Smith KM, van Lingen R, Warren F, et al (2021). A facilitated home-based cardiac rehabilitation intervention for people with heart failure and their caregivers: a research programme including the REACH-HF RCT. Programme Grants for Applied Research, 9(1).
McDonagh STJ, Sheppard JP, Warren FC, Boddy K, Farmer L, Shore H, Williams P, Lewis PS, Baumber R, Fordham J, et al (2021). Arm Based on LEg blood pressures (ABLE-BP): can systolic leg blood pressure measurements predict systolic brachial blood pressure? Protocol for an individual participant data meta-analysis from the INTERPRESS-IPD Collaboration. BMJ Open, 11(3), e040481-e040481. Abstract.
Richards DA, Sugg HVR, Cockcroft E, Cooper J, Cruickshank S, Doris F, Hulme C, Logan P, Iles-Smith H, Melendez-Torres GJ, et al (2021). COVID-NURSE: evaluation of a fundamental nursing care protocol compared with care as usual on experience of care for noninvasively ventilated patients in hospital with the SARS-CoV-2 virus—protocol for a cluster randomised controlled trial. BMJ Open, 11(5), e046436-e046436. Abstract.
Breedvelt JJF, Warren FC, Segal Z, Kuyken W, Bockting CL (2021). Continuation of Antidepressants vs Sequential Psychological Interventions to Prevent Relapse in Depression an Individual Participant Data Meta-analysis. JAMA PSYCHIATRY, 78(8), 868-875.  Author URL.
Smith K, Lang C, Wingham J, Frost J, Greaves C, Abraham C, Warren FC, Coyle J, Jolly K, Miles J, et al (2021). Process evaluation of a randomised pilot trial of home-based rehabilitation compared to usual care in patients with heart failure with preserved ejection fraction and their caregiver’s. Pilot and Feasibility Studies, 7(1). Abstract.
Wright K, Dodd A, Warren F, Medina-Lara A, Dunn B, Harvey J, Javaid M, Jones S, Owens C, Taylor R, et al (2021). Psychological Therapy for Mood Instability within Bipolar Spectrum Disorder: a Randomised, Controlled Feasibility Trial of a Dialectical Behaviour Therapy-Informed Approach (the ThrIVe-B Programme). International Journal of Bipolar Disorders, 9
Tarrant M, Carter M, Dean S, Taylor R, Warren F, Spencer A, Landa P, Adamson J, Code C, Backhouse A, et al (2021). Singing for people with aphasia (SPA): Results of a pilot feasibility randomised controlled trial of a group singing intervention investigating acceptability and feasibility. BMJ Open Abstract.
Clark C, Warren F, Boddy K, McDonagh S, Moore S, Goddard J, Reed N, Turner M, Alzamora MT, Ramos Blanes R, et al (2020). Associations Between Systolic Interarm Differences in Blood Pressure and Cardiovascular Disease Outcomes and Mortality: Individual Participant Data Meta-Analysis, Development and Validation of a Prognostic Algorithm: the INTERPRESS-IPD Collaboration. Hypertension, n/a, 1-12.
Breedvelt JJF, Warren FC, Brouwer ME, Karyotaki E, Kuyken W, Cuijpers P, van Oppen P, Gilbody S, Bockting CLH (2020). Individual participant data (IPD) meta-analysis of psychological relapse prevention interventions versus control for patients in remission from depression: a protocol. BMJ Open, 10(2). Abstract.  Author URL.
Newbold A, Warren FC, Taylor RS, Hulme C, Burnett S, Aas B, Botella C, Burkhardt F, Ehring T, Fontaine JRJ, et al (2020). Promotion of mental health in young adults via mobile phone app: study protocol of the ECoWeB (emotional competence for well-being in Young adults) cohort multiple randomised trials. BMC Psychiatry, 20(1). Abstract.  Author URL.
Butterworth J, Richards S, Warren F, Pitchforth E, Campbell J (2020). Randomised feasibility trial and embedded qualitative process evaluation of a new intervention to facilitate the involvement of older patients with multimorbidity in decision-making about their healthcare during general practice consultations: the VOLITION study protocol. Pilot Feasibility Stud, 6 Abstract.  Author URL.
Frost J, Wingham J, Britten N, Warren F, Taylor R (2020). The value of Social Practice Theory for implementation science: Learning from a theory-based mixed methods process evaluation of a randomised controlled trial. BMC Medical Research Methodology, 20, 181-181.
Clark CE, Masoli J, Warren FC, Soothill J, Campbell JL (2020). Vitamin D and COVID-19 in older age: evidence versus expectations. British Journal of General Practice, 71(702), 10-11.
Abel GA, Gomez-Cano M, Mustafee N, Smart A, Fletcher E, Salisbury C, Chilvers R, Dean SG, Richards SH, Warren F, et al (2020). Workforce predictive risk modelling: development of a model to identify general practices at risk of a supply-demand imbalance. BMJ Open, 10(1). Abstract.  Author URL.
Limond J, Wade SL, Vickery PJ, Jeffery A, Warren FC, Hawton A, Smithson J, Ford T, Haworth S, Adlam A-LR, et al (2019). Clinical and cost-effectiveness of teen online problem-solving for adolescents who have survived an acquired brain injury in the UK: protocol for a randomised, controlled feasibility study (TOPS-UK). BMJ Open, 9(8). Abstract.  Author URL.
Taylor R, Walker S, Ciani O, Warren F, Smart N, Piepoli M, Davos C (2019). Exercise Training for Chronic Heart Failure (ExTraMATCH II): Individual participant data meta-analysis of randomised controlled trials. NIHR Journals Library, 23
Smart NA, Taylor R, Walker S, Warren F, Ciani O, Davos CH, Piepoli M (2019). Exercise training for chronic heart failure (ExTraMATCH II): Why all data are not equal. Eur J Prev Cardiol, 26(11), 1229-1231.  Author URL.
Frost J, Wingham J, Britten N, Abraham C, Greaves C, Warren F, Jolly K, Doherty P, Miles J, Taylor R, et al (2019). Home-based rehabilitation for heart failure with reduced ejection fraction: Mixed methods process evaluation of the REACH-HF multicentre randomised controlled trial. BMJ Open
Taylor R, Walker S, Smart N, Warren FC, Piepoli MF, Ciani O, Whellan D, O'Connor C, Keteyian SJ, Coats A, et al (2019). Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure: Individual Participant Meta-Analysis. Journal of the American College of Cardiology, 73, 1430-1443.
Richards DA, Bazeley P, Borglin G, Craig P, Emsley R, Frost J, Hill J, Horwood J, Hutchings HA, Jinks C, et al (2019). Integrating quantitative and qualitative data and findings when undertaking randomised controlled trials. BMJ Open, 9(11), e032081-e032081. Abstract.
Ciani O, Walker S, Warren F, Smart N, Piepoli M, Davos C, Eames T, Taylor R (2019). OP91 Individual Participant Data Meta-Analysis of Exercise Rehabilitation in Heart Failure. International Journal of Technology Assessment in Health Care, 34(S1), 33-34.
Tikhonova I, Jones-Hughes T, Dunham J, Warren F, Robinson S, Hoyle M (2019). PP147 Olaratumab with Doxorubicin for Advanced Soft Tissue Sarcoma. International Journal of Technology Assessment in Health Care, 34(S1), 123-124.
Campbell JL, Fletcher E, Abel G, Anderson R, Chilvers R, Dean SG, Richards SH, Sansom A, Terry R, Aylward A, et al (2019). Policies and strategies to retain and support the return of experienced GPs in direct patient care: the ReGROUP mixed-methods study. Health Services and Delivery Research, 7(14), 1-288. Abstract.
Taylor RS, Smart NA, Warren FC, Dalal HM (2019). Reply: Exercise Capacity Characterization and Physical Activity Intensification Should be Priorities in Heart Failure Patients. Journal of the American College of Cardiology, 74(4), 590-591.
Taylor R, Sadler S, Dalal H, Warren FC, Jolly K, Davis RC, Doherty P, Miles J, Greaves C, Wingham J, et al (2019). The cost effectiveness of REACH-HF and home-based cardiac rehabilitation compared with usual medical care for heart failure with reduced ejection fraction: a decision model-based analysis. European Journal of Preventive Cardiology
Dalal HM, Lang CC, Smith K, Wingham J, Eyre V, Greaves CJ, Warren FC, Green C, Jolly K, Davis RC, et al (2018). A randomised controlled trial of a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction and their caregivers: REACH-HFpEF pilot study. British Journal of General Practice, 68(suppl 1).
Richards SH, Dickens C, Anderson R, Richards DA, Taylor RS, Ukoumunne OC, Turner KM, Gandhi M, Kuyken W, Gibson A, et al (2018). Assessing the effectiveness of Enhanced Psychological Care for patients with depressive symptoms attending cardiac rehabilitation compared with treatment as usual (CADENCE): a pilot cluster randomised controlled trial. Trials, 19(1). Abstract.  Author URL.
Tikhonova IA, Jones-Hughes T, Dunham J, Warren FC, Robinson S, Stephens P, Hoyle M (2018). Correction to: Olaratumab in Combination with Doxorubicin for the Treatment of Advanced Soft Tissue Sarcoma: an Evidence Review Group Perspective of a National Institute for Health and Care Excellence Single Technology Appraisal (PharmacoEconomics, (2018), 36, 1, (39-49), 10.1007/s40273-017-0568-3). PharmacoEconomics, 36(4). Abstract.
Clark CE, Thomas D, Warren F, Llewellyn D, Ferrucci L, Campbell J (2018). Detecting Risks of Postural Hypotension (DROP): derivation and validation of a prediction score for primary care. BMJ Open
Richards SH, Campbell JL, Dickens C, Anderson R, Gandhi M, Gibson A, Kessler D, Knight L, Kuyken W, Richards DA, et al (2018). Enhanced psychological care in cardiac rehabilitation services for patients with new-onset depression: the CADENCE feasibility study and pilot RCT. Health Technol Assess, 22(30), 1-220. Abstract.  Author URL.
Kirkpatrick T, Lennox C, Taylor R, Anderson R, Maguire M, Haddad M, Michie S, Owens C, Durcan G, Stirzaker A, et al (2018). Evaluation of a complex intervention (Engager) for prisoners with common mental health problems, near to and after release: study protocol for a randomised controlled trial. BMJ Open, 8(2). Abstract.  Author URL.
Carter M, Fletcher E, Sansom A, Warren FC, Campbell JL (2018). Feasibility, acceptability and effectiveness of an online alternative to face-to-face consultation in general practice: a mixed-methods study of webGP in six Devon practices. BMJ Open, 8(2). Abstract.  Author URL.
Clark C, Boddy K, Warren F, McDonagh S, Taylor R, Aboyans V, Cloutier L, McManus R, Shore A, Campbell J, et al (2018). INTER-ARM DIFFERENCES IN BLOOD PRESSURE AND MORTALITY: INDIVIDUAL PATIENT DATA META-ANALYSIS AND DEVELOPMENT OF a PROGNOSTIC ALGORITHM (INTERPRESS-IPD COLLABORATION). Canadian Journal of Cardiology, 34(10).
Taylor RS, Walker S, Smart NA, Piepoli MF, Warren FC, Ciani O, O'Connor C, Whellan D, Keteyian SJ, Coats A, et al (2018). Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials. Eur J Heart Fail, 20(12), 1735-1743. Abstract.  Author URL.
Wright K, Dodd A, Warren FC, Medina-Lara A, Taylor R, Jones S, Owens C, Javaid M, Dunn B, Harvey JE, et al (2018). The clinical and cost effectiveness of adapted dialectical behaviour therapy (DBT) for bipolar mood instability in primary care (ThrIVe-B programme): a feasibility study. Trials, 19(1). Abstract.  Author URL.
Ciani O, Piepoli M, Smart N, Uddin J, Walker S, Warren FC, Zwisler AD, Davos CH, Taylor RS (2018). Validation of Exercise Capacity as a Surrogate Endpoint in Exercise-Based Rehabilitation for Heart Failure: a Meta-Analysis of Randomized Controlled Trials. JACC: Heart Failure, 6(7), 596-604. Abstract.
Clark CE, Boddy K, Warren FC, Taylor RS, Aboyans V, Cloutier L, McManus RJ, Shore AC, Campbell JL (2017). Associations between interarm differences in blood pressure and cardiovascular disease outcomes: protocol for an individual patient data meta-analysis and development of a prognostic algorithm. BMJ Open, 7(6). Abstract.  Author URL.
Richards DA, Rhodes S, Ekers D, McMillan D, Taylor RS, Byford S, Barrett B, Finning K, Ganguli P, Warren F, et al (2017). Cost and Outcome of BehaviouRal Activation (COBRA): a randomised controlled trial of behavioural activation versus cognitive-behavioural therapy for depression. Health Technol Assess, 21(46), 1-366. Abstract.  Author URL.
Burt J, Campbell J, Abel G, Aboulghate A, Ahmed F, Asprey A, Barry H, Beckwith J, Benson J, Boiko O, et al (2017). Improving patient experience in primary care: a multimethod programme of research on the measurement and improvement of patient experience. Programme Grants for Applied Research, 5(9), 1-452. Abstract.
Tikhonova I, Jones-Hughes T, Dunham J, Warren F, Robinson S, Stephens P, Hoyle M (2017). Olaratumab in Combination with Doxorubicin for the Treatment of Advanced Soft Tissue Sarcoma: an Evidence Review Group Perspective of a National Institute for Health and Care Excellence Single Technology Appraisal. Pharmacoeconomics
Fletcher E, Abel GA, Anderson R, Richards SH, Salisbury C, Dean SG, Sansom A, Warren FC, Campbell JL (2017). Quitting patient care and career break intentions among general practitioners in South West England: findings of a census survey of general practitioners. BMJ Open, 7(4). Abstract.  Author URL.
Thompson TP, Greaves CJ, Ayres R, Aveyard P, Warren FC, Byng R, Taylor RS, Campbell JL, Ussher M, Green C, et al (2016). An Exploratory Analysis of the Smoking and Physical Activity Outcomes from a Pilot Randomized Controlled Trial of an Exercise Assisted Reduction to Stop Smoking Intervention in Disadvantaged Groups. Nicotine Tob Res, 18(3), 289-297. Abstract.  Author URL.
Richards SH, Dickens C, Anderson R, Richards DA, Taylor RS, Ukoumunne OC, Kessler D, Turner K, Kuyken W, Gandhi M, et al (2016). Assessing the effectiveness of enhanced psychological care for patients with depressive symptoms attending cardiac rehabilitation compared with treatment as usual (CADENCE): study protocol for a pilot cluster randomised controlled trial. Trials, 17 Abstract.  Author URL.
Richards DA, Ekers D, McMillan D, Taylor RS, Byford S, Warren FC, Barrett B, Farrand PA, Gilbody S, Kuyken W, et al (2016). Cost and Outcome of Behavioural Activation versus Cognitive Behavioural Therapy for Depression (COBRA): a randomised, controlled, non-inferiority trial. Lancet
Warren FC, Kuyken W, Taylor RS, Whalley B, Crane C, Bondolfi G, Hayes R, Huijbers M, Ma H, Schwelzer S, et al (2016). Efficacy of mindfulness-based cognitive therapy in prevention of depressive relapse: an individual patient data meta-analysis from randomized trials. JAMA Psychiatry
Thompson TP, Greaves CJ, Ayres R, Aveyard P, Warren FC, Byng R, Taylor RS, Campbell JL, Ussher M, Michie S, et al (2016). Factors associated with study attrition in a pilot randomised controlled trial to explore the role of exercise-assisted reduction to stop (EARS) smoking in disadvantaged groups. Trials, 17(1). Abstract.  Author URL.
Holt T, Fletcher E, Warren F, Richards S, Calitri R, Green C (2016). Telephone triage systems in UK general practice: analysis of consultation duration during the index day in a pragmatic randomised controlled trial. Br J Gen Pract
Varley A, Warren FC, Richards SH, Calitri R, Chaplin K, Fletcher E, Holt TA, Lattimer V, Murdoch J, Richards DA, et al (2016). The effect of nurses’ preparedness and nurse practitioner status on triage call management in primary care: a secondary analysis of cross-sectional data from the ESTEEM trial. International Journal of Nursing Studies, 58, 12-20.
White A, Tough L, Eyre V, Vickery J, Asprey A, Quinn C, Warren F, Pritchard C, Foster NE, Taylor RS, et al (2016). Western medical acupuncture in a group setting for knee osteoarthritis: results of a pilot randomised controlled trial. Pilot Feasibility Stud, 2 Abstract.  Author URL.
Clark C, Thomas D, Warren F, Llewellyn D, Ferrucci L, Campbell J (2016). [OP.3C.04] PREDICTING POSTURAL HYPOTENSION, FALLS, AND COGNITIVE IMPAIRMENT: THE INCHIANTI STUDY. J Hypertens, 34 Suppl 2 Abstract.  Author URL.
Warren FC, Abel G, Lyratzopoulos G, Elliott MN, Richards S, Barry HE, Roland M, Campbell JL (2015). Characteristics of service users and provider organisations associated with experience of out of hours general practitioner care in England: population based cross sectional postal questionnaire survey. BMJ, 350 Abstract.  Author URL.
Taylor RS, Hayward C, Eyre V, Austin J, Davies R, Doherty P, Jolly K, Wingham J, Van Lingen R, Abraham C, et al (2015). Clinical effectiveness and cost-effectiveness of the Rehabilitation Enablement in Chronic Heart Failure (REACH-HF) facilitated self-care rehabilitation intervention in heart failure patients and caregivers: rationale and protocol for a multicentre randomised controlled trial. BMJ Open, 5(12). Abstract.  Author URL.
Pentecost C, Farrand P, Greaves CJ, Taylor RS, Warren FC, Hillsdon M, Green C, Welsman JR, Rayson K, Evans PH, et al (2015). Combining behavioural activation with physical activity promotion for adults with depression: findings of a parallel-group pilot randomised controlled trial (BAcPAc). Trials, 16(367), 1-15. Abstract.
Calitri RA, Warren FC, Wheeler B, Chaplin K, Fletcher E, Murdoch J, Richards SH, Taylor R, Varley A, Campbell JL, et al (2015). Distance from practice moderates the relationship between patient management involving nurse telephone triage consulting and patient satisfaction with care. Journal of Health & Place Abstract.
Zhou Y, Abel G, Warren F, Roland M, Campbell J, Lyratzopoulos G (2015). Do difficulties in accessing in-hours primary care predict higher use of out-of-hours GP services? Evidence from an English National Patient Survey. Emerg Med J, 32(5), 373-378. Abstract.  Author URL.
Taylor RS, Piepoli MF, Smart N, Coats AJS, Ellis S, Dalal H, O'Connor CM, Warren FC, Whellan D, Ciani O, et al (2015). Erratum: Corrigendum to exercise training for chronic heart failure (ExTraMATCH II): Protocol for an individual participant data meta-analysis (Int J Cardiol. (2014) 174:3 (683-687) DOI: http://dx.doi.org/10.1016/j.ijcard.2014.04.203). International Journal of Cardiology, 193
Warren FC, Calitri R, Fletcher E, Varley A, Holt TA, Lattimer V, Richards D, Richards S, Salisbury C, Taylor RS, et al (2015). Exploring demographic and lifestyle associations with patient experience following telephone triage by a primary care doctor or nurse: secondary analyses from a cluster randomised controlled trial. BMJ Qual Saf, 24(9), 572-582. Abstract.  Author URL.
Campbell JL, Fletcher E, Britten N, Green C, Holt T, Lattimer V, Richards DA, Richards SH, Salisbury C, Taylor RS, et al (2015). The clinical effectiveness and cost-effectiveness of telephone triage for managing same-day consultation requests in general practice: a cluster randomised controlled trial comparing general practitioner-led and nurse-led management systems with usual care (the ESTEEM trial). Health Technol Assess, 19(13), 1-viii. Abstract.  Author URL.
Taylor AH, Thompson TP, Greaves CJ, Taylor RS, Green C, Warren FC, Kandiyali R, Aveyard P, Ayres R, Byng R, et al (2014). A pilot randomised trial to assess the methods and procedures for evaluating the clinical effectiveness and cost-effectiveness of Exercise Assisted Reduction then Stop (EARS) among disadvantaged smokers. Health Technol Assess, 18(4), 1-324. Abstract.  Author URL.
Farrand P, Pentecost C, Greaves C, Taylor RS, Warren F, Green C, Hillsdon M, Evans P, Welsman J, Taylor AH, et al (2014). A written self-help intervention for depressed adults comparing behavioural activation combined with physical activity promotion with a self-help intervention based upon behavioural activation alone: study protocol for a parallel group pilot randomised controlled trial (BAcPAc). Trials, 15 Abstract.  Author URL.
Taylor RS, Piepoli MF, Smart N, Coats AJS, Ellis S, Dalal H, O'Connor CM, Warren FC, Whellan D, Ciani O, et al (2014). Corrigendum to exercise training for chronic heart failure (ExTraMATCH II): Protocol for an individual participant data meta-analysis Int J Cardiol. 2014 Jul 1;174(3):683-7. International Journal of Cardiology
Warren FC, Stych K, Thorogood M, Sharp DJ, Murphy M, Turner KM, Holt TA, Searle A, Bryant S, Huxley C, et al (2014). Evaluation of different recruitment and randomisation methods in a trial of general practitioner-led interventions to increase physical activity: a randomised controlled feasibility study with factorial design. Trials, 15(1). Abstract.
Taylor RS, Piepoli MF, Smart N, Coats AJS, Ellis S, Dalal H, O'Connor CM, Warren FC, Whellan D, Ciani O, et al (2014). Exercise training for chronic heart failure (ExTraMATCH II): protocol for an individual participant data meta-analysis. Int J Cardiol, 174(3), 683-687. Abstract.  Author URL.
Warren FC, Abrams KR, Sutton AJ (2014). Hierarchical network meta-analysis models to address sparsity of events and differing treatment classifications with regard to adverse outcomes. Stat Med, 33(14), 2449-2466. Abstract.  Author URL.
O'Mahen HA, Richards DA, Woodford J, Wilkinson E, McGinley J, Taylor RS, Warren FC (2014). Netmums: a phase II randomized controlled trial of a guided Internet behavioural activation treatment for postpartum depression. Psychological Medicine, 44, 1675-1689. Abstract.
Nicholson KG, Abrams KR, Batham S, Medina MJ, Warren FC, Barer M, Bermingham A, Clark TW, Latimer N, Fraser M, et al (2014). Randomised controlled trial and health economic evaluation of the impact of diagnostic testing for influenza, respiratory syncytial virus and Streptococcus pneumoniae infection on the management of acute admissions in the elderly and high-risk 18- to 64-year-olds. Health Technol Assess, 18(36), 1-viii. Abstract.  Author URL.
Campbell JL, Fletcher E, Britten N, Green C, Holt TA, Lattimer V, Richards DA, Richards SH, Salisbury C, Calitri R, et al (2014). Telephone triage for management of same-day consultation requests in general practice (the ESTEEM trial): a cluster-randomised controlled trial and cost-consequence analysis. Lancet, 384(9957), 1859-1868.
Haasova M, Warren FC, Ussher M, Van Rensburg KJ, Faulkner G, Cropley M, Byron-Daniel J, Everson-Hock ES, Oh H, Taylor AH, et al (2014). The acute effects of physical activity on cigarette cravings: Exploration of potential moderators, mediators and physical activity attributes using individual participant data (IPD) meta-analyses. Psychopharmacology
O'Mahen H, Woodford J, McKinley J, Warren F, Richards D, Lynch T, Taylor R (2013). Internet-based Behavioral Activation Treatment for Postnatal Depression (Netmums): a Randomized Controlled Trial. Journal of Affective Disorders Abstract.
O'Mahen HA, Woodford J, McGinley J, Warren FC, Richards DA, Lynch TR, Taylor RS (2013). Internet-based behavioral activation-Treatment for postnatal depression (Netmums): a randomized controlled trial. Journal of Affective Disorders, 150(3), 814-822. Abstract.
Haasova M, Warren FC, Ussher M, Janse Van Rensburg K, Faulkner G, Cropley M, Byron-Daniel J, Everson-Hock ES, Oh H, Taylor AH, et al (2013). The acute effects of physical activity on cigarette cravings: Systematic review and meta-analysis with individual participant data. Addiction, 108(1), 26-37.
Haasova M, Warren FC, Ussher M, Janse Van Rensburg K, Faulkner G, Cropley M, Byron-Daniel J, Everson-Hock ES, Oh H, Taylor AH, et al (2013). The acute effects of physical activity on cigarette cravings: systematic review and meta-analysis with individual participant data. Addiction, 108(1), 26-37. Abstract.  Author URL.
Gray LJ, Cooper N, Dunkley A, Warren FC, Ara R, Abrams K, Davies MJ, Khunti K, Sutton A (2012). A systematic review and mixed treatment comparison of pharmacological interventions for the treatment of obesity. Obes Rev, 13(6), 483-498. Abstract.  Author URL.
Thompson TP, Aveyard P, Ayres R, Taylor R, Warren F, Campbell J, Byng R, Ussher M, Michie S, West R, et al (2012). Strategies to recruit hard-to-reach smokers into Exercise Assisted Reduction then Stop (EARS): a pragmatic pilot randomised trial. The Lancet, 380
Warren FC, Abrams KR, Golder S, Sutton AJ (2012). Systematic review of methods used in meta-analyses where a primary outcome is an adverse or unintended event. BMC Medical Research Methodology, 12(64).
Ara R, Blake L, Gray L, Hernández M, Crowther M, Dunkley A, Warren F, Jackson R, Rees A, Stevenson M, et al (2012). What is the clinical effectiveness and cost-effectiveness of using drugs in treating obese patients in primary care? a systematic review. Health Technology Assessment, 16(5). Abstract.
Nicholson KG, Abrams KR, Batham S, Clark TW, Hoschler K, Lim WS, Medina M-J, Nguyen-Van-Tam JS, Read RC, Warren FC, et al (2011). Immunogenicity and safety of a two-dose schedule of whole-virion and AS03A-adjuvanted 2009 influenza a (H1N1) vaccines: a randomised, multicentre, age-stratified, head-to-head trial. Lancet Infect Dis, 11(2), 91-101. Abstract.  Author URL.
Nicholson KG, Abrams KR, Batham S, Clark TW, Hoschler K, Lim WS, Medina M, Nguyen-Van-Tam JS, Read RC, Warren FC, et al (2010). A randomised, partially observer blind, multicentre, head-to-head comparison of a two-dose regimen of Baxter and GlaxoSmithKline H1N1 pandemic vaccines, administered 21 days apart. Health Technol Assess, 14(55), 193-334. Abstract.  Author URL.
Bongartz T, Warren FC, Mines D, Matteson EL, Abrams KR, Sutton AJ (2009). Etanercept therapy in rheumatoid arthritis and the risk of malignancies. A systematic review and individual patient data meta-analysis of Randomized Controlled Trials. Annals of the Rheumatic Diseases, 68, 1177-1183.
Jones DR, Sutton AJ, Fenty J, Warren F, Rushton L (2009). Systematic review and meta-analysis of mortality in crop protection product manufacturing workers. Occupational and Environmental Medicine, 66, 7-15.
Alder N, Fenty J, Warren F, Sutton AJ, Rushton L, Jones DR, Abrams KR (2006). Meta-analysis of mortality and cancer incidence among workers in the synthetic rubber-producing industry.[see comment]. American Journal of Epidemiology, 164, 405-420. Abstract.
Brown TP, Shuker LK, Rushton L, Warren F, Stevens J (2001). The possible effects on health, comfort and safety of aircraft cabin environments. Journal of the Royal Society of Health, 121, 177-184.

Chapters

Taylor RS, Ukoumunne OC, Warren FC (2015). How to use feasibility and pilot trials to test alternative methodologies and methodological procedures prior to full-scale trials. In  (Ed) Complex Interventions in Health: an Overview of Research Methods, 136-144.
Ukoumunne OC, Warren FC, Taylor RS, Ewings P (2015). How to use feasibility studies to derive parameter estimates in order to power a full trial. In  (Ed) Complex Interventions in Health: an Overview of Research Methods, 145-154.

Conferences

Stokes I, Warren F, Hay-Smith J, Elders A, Bugge C, Hagen S, Dean S (2022). Pelvic Floor Muscle Training Adherence: evaluating women’s adherence to home exercise prescription in a multicentre randomised controlled trial. 7th - 10th Sep 2022.
Major K, Warren F, Hay-Smith J, Bugge C, Hagen S, Elders A, Dean S (2022). Promoting adherence to pelvic floor muscle exercises: analysis of exercise prescription, prompts to exercise, and predictors of exercise diary return, during a randomised controlled trial.  Author URL.
Mcdonagh S, Sheppard J, Warren F, Boddy K, Fordham J, Farmer L, Lewis P, Baumber R, Martin U, Clark C, et al (2021). ARM BASED ON LEG BLOOD PRESSURES (ABLE-BP): CAN LEG BLOOD PRESSURE MEASUREMENTS PREDICT BRACHIAL BLOOD PRESSURE? INDIVIDUAL PARTICIPANT DATA META-ANALYSIS FROM THE INTERPRESS-IPD.  Author URL.
McDonagh S, Sheppard J, Warren F, Boddy K, Farmer L, Shore H, Williams P, Lewis P, Baumber R, Fordham AJ, et al (2021). Arm based on LEg blood pressures (ABLE-BP): can leg blood pressure measurements predict brachial blood pressure? an individual participant data meta-analysis from the INTERPRESS-IPD Collaboration.  Author URL.
Clark C, Boddy K, Warren F, Mcdonagh S, Moore S, Aboyans V, Cloutier L, McManus R, Shore A, Taylor R, et al (2021). SYSTOLIC INTER-ARM BLOOD PRESSURE DIFFERENCE AND COGNITIVE DECLINE: FINDINGS FROM THE INTERPRESS-IPD COLLABORATION.  Author URL.
Clark C, Warren F, Boddy K, McDonagh S, Moore S, Cloutier L, Taylor R, Shore A, McManus R, Aboyans V, et al (2021). Which arm to measure blood pressure: does the higher or lower reading arm best reflect systolic blood pressure? an individual participant data meta-analysis from the INTERPRESS-IPD Collaboration.  Author URL.
Clark C, Boddy K, Warren F, McDonagh S, Moore S, Aboyans V, Cloutier L, McManus R, Shore A, Taylor R, et al (2020). Systolic inter-arm blood pressure difference and cognitive decline: findings from the INTERPRESS-IPD Collaboration.  Author URL.
Clark C, Warren F, Boddy K, McDonagh S, Moore S, Cloutier L, Taylor R, Shore A, McManus R, Aboyans V, et al (2019). INTER-ARM BLOOD PRESSURE DIFFERENCE: INSIGHTS INTO AETIOLOGY FROM THE INTERPRESS-IPD COLLABORATION.  Author URL.
Clark C, Warren F, Boddy K, McDonagh S, Moore S, Cloutier L, Taylor R, Shore A, McManus R, Aboyans V, et al (2019). Inter-arm blood pressure difference: insights into aetiology from the INTERPRESS-IPD collaboration.  Author URL.
Calitri R, Mounce L, Abel G, Campbell J, Spencer A, Medina-Lara A, Pitt M, Shepard E, Warren F, Dean S, et al (2019). Protocol for a pragmatic cluster randomised controlled trial assessing the clinical effectiveness and cost effectiveness of electronic risk-assessment tools for cancer for patients in general practice (ERICA).  Author URL.
Ciani O, Walker S, Taylor RS (2018). IMPACT OF EXERCISE-BASED REHABILITATION IN PATIENTS WITH HEART FAILURE (EXTRAMATCH II) ON EXERCISE CAPACITY AND HEALTH-RELATED QUALITY OF LIFE: a META-ANALYSIS OF INDIVIDUAL PARTICIPANT DATA FROM RANDOMISED TRIALS.  Author URL.
Clark C, Boddy K, Warren F, Mcdonagh S, Taylor R, Aboyans V, Cloutier L, McManus R, Shore A, Campbell J, et al (2018). INTER-ARM DIFFERENCES IN BLOOD PRESSURE AND MORTALITY: INDIVIDUAL PATIENT DATA META-ANALYSIS AND DEVELOPMENT OF a PROGNOSTIC ALGORITHM (INTERPRESSIPD COLLABORATION).  Author URL.
Tikhonova I, Jones-Hughes T, Dunham J, Warren F, Robinson S, Hoyle M (2018). Olaratumab with doxorubicin for advanced soft tissue sarcoma. HTAi 2018. 1st - 5th Jun 2018.
Dalal H, Jolly K, Davis R, Doherty P, Austin J, van Lingen R, Warren F, Green C, Wingham J, Britten N, et al (2018). REHABILITATION ENABLEMENT IN CHRONIC HEART FAILURE (REACH-HF) a MULTICENTRE RANDOMISED CONTROLLED TRIAL OF FACILITATED SELF-CARE REHABILITATION INTERVENTION IN HEART FAILURE WITH REDUCED EJECTION FRACTION.  Author URL.
Tarrant M, Carter M, Adamson J, Warren F, Taylor R, Spencer A, Landa P, Code C, Dean S, Calitri R, et al (2018). Singing for People with Aphasia (SPA): results of a pilot randomised controlled trial of a group singing intervention to improve wellbeing.  Author URL.
Lang CC, Smith K, Wingham J, Eyre V, Greaves CJ, Warren F, Green C, Jolly K, Russell D, Abhraham C, et al (2017). A Facilitated Home Based Rehabilitation Intervention: Impact on Well-Being and Quality of Life in Patients with Heart Failure with Preserved Ejection Fraction.  Author URL.
Clark C, Warren F, Boddy K, Taylor R, Shore A, Aboyans V, Cloutier L, McManus R, Campbell J (2016). INTERPRESS-IPD: THE INTER-ARM BLOOD PRESSURE DIFFERENCE INDIVIDUAL PATIENT DATA COLLABORATION.  Author URL.
Bongartz T, Warren FC, Mines D, Matteson EL, Abrams KR, Sutton AJ (2008). Etanercept therapy in rheumatoid arthritis and the risk of malignancy: a systematic review and individual patient data-based meta-analysis of randomized controlled trials.  Author URL.
Rushton L, Fenty J, Jones DR, Sutton AJ, Warren FC, Abrams K, Levy LS (2005). Systematic review and meta-analysis of mortality among workers in the crop protection sector of the chemical industry: Methodological issues arising.  Author URL.
Levy LS, Aitken R, Holmes P, Hughes J, Hurley F, Rumsby PC, Searl A, Shuker LK, Spurgeon A, Warren FC, et al (2004). The derivation of a health-based occupational exposure limit for maganese using human neurobehaviour/neurotoxicity data.  Author URL.

Reports

Taylor R, Walker S, Ciani O, Warren FC, Smart NA, Piepoli M, Davos CH (2019). Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis.

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Teaching

I have an interest in teaching medical statistics to undergraduate medical students (developed while pursuing my PhD), and continue to support teaching on the BMBS programme as part of the Making Sense of Evidence module. I am also the module convenor for the Statistics as Applied to Health module, which is part of the MSc Health Research Methods.

Modules

2023/24


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Supervision / Group

Postgraduate researchers

  • Abdullah Al Haj Yonis

Alumni

  • Marcela Haasova Completed PhD thesis 2013

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