Loading content
Dr Eva Latorre

Dr Eva Latorre

Associate Research Fellow

 6772

 RILD Building RNA - Mediated Mechanisms of D

 

University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK

Eva is currently working in the RNA - Mediated Mechanisms of Disease group with Dr. Lorna Harries. She interested in gene regulation and alternative messenger RNA processing in human ageing.

Broad Research Specialisms

  • Cell culture
  • Ageing
  • Cellular senescence
  • Oxidative Stress
  • Inflammation
  • Innate immune system

Qualifications

  • 2015 PhD. Biomedical and Biotechnological Sciences (University of Zaragoza)
  • 2010 MSc. Veterinary Sciences Research (University of Zaragoza)
  • 2009 BSc. Veterinary Medicine (University of Zaragoza)

Links

Research

Research interests

Eva works in understanding the global deterioration in cell function that occurs as we age. her current study focuses on the role of alternative messenger RNA processing and RNA regulation of genes involved in ageing.

Research projects

Role of age-associated inflammation in moderation of alternative splicing and its impact on age-related disease.

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Forcén R, Latorre E, Pardo J, Alcalde AI, Murillo MD, Grasa L (In Press). Toll-like receptors 2 and 4 exert opposite effects on the contractile response induced by serotonin in mouse colon: role of serotonin receptors. Exp Physiol, 101(8), 1064-1074. Abstract.  Author URL.
Layunta E, Latorre E, Forcén R, Grasa L, Plaza MA, Arias M, Alcalde AI, Mesonero JE (2018). NOD1 downregulates intestinal serotonin transporter and interacts with other pattern recognition receptors. J Cell Physiol, 233(5), 4183-4193. Abstract.  Author URL.
Latorre E, Pilling LC, Lee BP, Bandinelli S, Melzer D, Ferrucci L, Harries LW (2018). The VEGFA156b isoform is dysregulated in senescent endothelial cells and may be associated with prevalent and incident coronary heart disease. Clin Sci (Lond), 132(3), 313-325. Abstract.  Author URL.  Full text.
Jeynes JCG, Geraki K, Jeynes C, Zhaohong M, Bettiol AA, Latorre E, Harries LW, Soeller C (2017). Nanoscale Properties of Human Telomeres Measured with a Dual Purpose X-ray Fluorescence and Super Resolution Microscopy Gold Nanoparticle Probe. ACS Nano, 11(12), 12632-12640. Abstract.  Author URL.  Full text.
Peralta P, Gascón A, Latorre E (2017). Occupational Therapy Prevents Cognitive Impairment on Long-Term Care Residents. Physical & Occupational Therapy in Geriatrics, 35(3-4), 119-131.
Latorre E, Birar VC, Sheerin AN, Jeynes JCC, Hooper A, Dawe HR, Melzer D, Cox LS, Faragher RGA, Ostler EL, et al (2017). Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence. BMC Cell Biol, 18(1). Abstract.  Author URL.  Full text.
Latorre E, Harries LW (2017). Splicing regulatory factors, ageing and age-related disease. Ageing Res Rev, 36, 165-170. Abstract.  Author URL.  Full text.
Latorre E, Layunta E, Grasa L, Pardo J, García S, Alcalde AI, Mesonero JE (2017). Toll-like receptors 2 and 4 modulate intestinal IL-10 differently in ileum and colon. United European Gastroenterology Journal, 205064061772718-205064061772718.
Latorre E, Layunta E, Grasa L, Castro M, Pardo J, Gomoll n F, Alcalde AI, Mesonero JE (2016). Intestinal serotonin transporter inhibition by toll-like receptor 2 activation. A feedback modulation. PLoS ONE, 11(12). Abstract.  Full text.
Latorre Duque E (2016). Listeria monocytogenes Inhibits Serotonin Transporter in Human Intestinal Caco-2 Ce. Microbial Ecology: an international journal Full text.
Grasa L, Abecia L, Forcén R, Castro M, de Jalón JAG, Latorre E, Alcalde AI, Murillo MD (2015). Antibiotic-Induced Depletion of Murine Microbiota Induces Mild Inflammation and Changes in Toll-Like Receptor Patterns and Intestinal Motility. Microb Ecol, 70(3), 835-848. Abstract.  Author URL.
Forcén R, Latorre E, Pardo J, Alcalde AI, Murillo MD, Grasa L (2015). Toll-like receptors 2 and 4 modulate the contractile response induced by serotonin in mouse ileum: analysis of the serotonin receptors involved. Neurogastroenterol Motil, 27(9), 1258-1266. Abstract.  Author URL.
Latorre E, Matheus N, Layunta E, Alcalde AI, Mesonero JE (2014). IL-10 Counteracts Proinflammatory Mediator Evoked Oxidative Stress in Caco-2 Cells. Mediators of Inflammation, 2014, 1-6.
Latorre E, Mendoza C, Layunta E, Alcalde AI, Mesonero JE (2014). TLR2, TLR3, and TLR4 activation specifically alters the oxidative status of intestinal epithelial cells. Cell Stress and Chaperones, 19(2), 289-293. Abstract.
Latorre E, Mendoza C, Matheus N, Castro M, Grasa L, Mesonero JE, Alcalde AI (2013). IL-10 modulates serotonin transporter activity and molecular expression in intestinal epithelial cells. Cytokine, 61(3), 778-784. Abstract.
Mendoza C, Matheus N, Latorre E, Castro M, Mesonero JE, Alcalde AI (2012). Toll-like receptor 3 activation affects serotonin transporter activity and expression in human enterocyte-like caco-2 cells. Cellular Physiology and Biochemistry, 30(1), 187-198. Abstract.

Publications by year


In Press

Forcén R, Latorre E, Pardo J, Alcalde AI, Murillo MD, Grasa L (In Press). Toll-like receptors 2 and 4 exert opposite effects on the contractile response induced by serotonin in mouse colon: role of serotonin receptors. Exp Physiol, 101(8), 1064-1074. Abstract.  Author URL.

2018

Layunta E, Latorre E, Forcén R, Grasa L, Plaza MA, Arias M, Alcalde AI, Mesonero JE (2018). NOD1 downregulates intestinal serotonin transporter and interacts with other pattern recognition receptors. J Cell Physiol, 233(5), 4183-4193. Abstract.  Author URL.
Latorre E, Pilling LC, Lee BP, Bandinelli S, Melzer D, Ferrucci L, Harries LW (2018). The VEGFA156b isoform is dysregulated in senescent endothelial cells and may be associated with prevalent and incident coronary heart disease. Clin Sci (Lond), 132(3), 313-325. Abstract.  Author URL.  Full text.

2017

Jeynes JCG, Geraki K, Jeynes C, Zhaohong M, Bettiol AA, Latorre E, Harries LW, Soeller C (2017). Nanoscale Properties of Human Telomeres Measured with a Dual Purpose X-ray Fluorescence and Super Resolution Microscopy Gold Nanoparticle Probe. ACS Nano, 11(12), 12632-12640. Abstract.  Author URL.  Full text.
Peralta P, Gascón A, Latorre E (2017). Occupational Therapy Prevents Cognitive Impairment on Long-Term Care Residents. Physical & Occupational Therapy in Geriatrics, 35(3-4), 119-131.
Latorre E, Birar VC, Sheerin AN, Jeynes JCC, Hooper A, Dawe HR, Melzer D, Cox LS, Faragher RGA, Ostler EL, et al (2017). Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence. BMC Cell Biol, 18(1). Abstract.  Author URL.  Full text.
Latorre E, Harries LW (2017). Splicing regulatory factors, ageing and age-related disease. Ageing Res Rev, 36, 165-170. Abstract.  Author URL.  Full text.
Latorre E, Layunta E, Grasa L, Pardo J, García S, Alcalde AI, Mesonero JE (2017). Toll-like receptors 2 and 4 modulate intestinal IL-10 differently in ileum and colon. United European Gastroenterology Journal, 205064061772718-205064061772718.

2016

Latorre E, Layunta E, Grasa L, Castro M, Pardo J, Gomoll n F, Alcalde AI, Mesonero JE (2016). Intestinal serotonin transporter inhibition by toll-like receptor 2 activation. A feedback modulation. PLoS ONE, 11(12). Abstract.  Full text.
Latorre Duque E (2016). Listeria monocytogenes Inhibits Serotonin Transporter in Human Intestinal Caco-2 Ce. Microbial Ecology: an international journal Full text.

2015

Grasa L, Abecia L, Forcén R, Castro M, de Jalón JAG, Latorre E, Alcalde AI, Murillo MD (2015). Antibiotic-Induced Depletion of Murine Microbiota Induces Mild Inflammation and Changes in Toll-Like Receptor Patterns and Intestinal Motility. Microb Ecol, 70(3), 835-848. Abstract.  Author URL.
Forcén R, Latorre E, Pardo J, Alcalde AI, Murillo MD, Grasa L (2015). Toll-like receptors 2 and 4 modulate the contractile response induced by serotonin in mouse ileum: analysis of the serotonin receptors involved. Neurogastroenterol Motil, 27(9), 1258-1266. Abstract.  Author URL.

2014

Latorre E, Matheus N, Layunta E, Alcalde AI, Mesonero JE (2014). IL-10 Counteracts Proinflammatory Mediator Evoked Oxidative Stress in Caco-2 Cells. Mediators of Inflammation, 2014, 1-6.
Latorre E, Mendoza C, Layunta E, Alcalde AI, Mesonero JE (2014). TLR2, TLR3, and TLR4 activation specifically alters the oxidative status of intestinal epithelial cells. Cell Stress and Chaperones, 19(2), 289-293. Abstract.

2013

Latorre E, Mendoza C, Matheus N, Castro M, Grasa L, Mesonero JE, Alcalde AI (2013). IL-10 modulates serotonin transporter activity and molecular expression in intestinal epithelial cells. Cytokine, 61(3), 778-784. Abstract.

2012

Mendoza C, Matheus N, Latorre E, Castro M, Mesonero JE, Alcalde AI (2012). Toll-like receptor 3 activation affects serotonin transporter activity and expression in human enterocyte-like caco-2 cells. Cellular Physiology and Biochemistry, 30(1), 187-198. Abstract.

Eva_Latorre Details from cache as at 2018-06-23 05:05:49

Refresh publications

Back | Edit Profile