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University of Exeter Medical School

Dr Elizabeth Goodwin

Dr Elizabeth Goodwin

Research Fellow

 E.Goodwin@exeter.ac.uk

 6073

 01392 726073

 South Cloisters 1.06

 

South Cloisters, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK


Overview

Prior to her academic career, Liz held a series of roles in Plymouth City Council’s housing and social care departments, encompassing homelessness and housing advice, development of carers support services, IT project implementation and performance management. She made the switch to Health Economics in 2008 by taking on a trainee position as a Health Economist with NHS Plymouth, during which she completed an MSc in Health Economics and Health Policy at the University of Birmingham.

Liz joined the Health Economics Group in 2011 to study full-time for a PhD and has remained within the Group, having been employed as a Research Fellow in Health Economics since April 2014.

Broad research specialisms

Liz’s research, which is funded by the MS Society, aims to extend and improve the data available to inform the assessment of treatments and services for multiple sclerosis (MS).  This includes developing a health outcome measure for MS that is suitable for use in economic evaluations, quantifying the impact of fatigue on the quality of life of people with MS, and exploring the impacts of MS on people's broader wellbeing and employment choices.

Having worked as a commissioner for the NHS, Liz retains an interest in the ways that decisions are made regarding the allocation of healthcare resources at a local level, and has published an account of her own experience of implementing and evaluating a systematic resource allocation method (programme budgeting and marginal analysis) within NHS Plymouth.

Twitter account: @madjka

Qualifications

  • 1992 BSc (Hons) Economics and Politics (University of Bath)
  • 1993 MSc Information Technology for Manufacture (University of Warwick)
  • 2006 MSc Social Research (University of Plymouth)
  • 2011 MSc Health Economics and Health Policy (University of Birmingham)
  • 2014: PhD Medical Studies, specialising in Health Economics (University of Exeter Medical School)

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Research

Research interests

Liz’s main research interests are methodological, with a particular focus on how the effects of healthcare interventions on patients’ health-related quality of life and broader wellbeing can be measured in a way that is suitable for economic evaluations. Specialising in multiple sclerosis (MS), her recent work has centred on the development of an MS-specific preference-based measure, the MSIS-8D, which can be used to generate the weights required to calculate QALYs (quality-adjusted life-years), the primary metric used by healthcare decision-makers in the UK to capture health outcomes for cost-effectiveness analysis. She has also used the MSIS-8D to explore how and why the preferences of people with MS for MSIS-8D health states differ from the preferences of the general population. In other research, Liz has used existing data to map Fatigue Severity Scale scores to two commonly used generic QALY measures (EQ-5D and SF-6D), enabling the impact of fatigue to be included in cost-effectiveness assessments of treatments for MS, and investigated the factors that influence the decisions that people with MS make regarding their employment.

Liz is currently working with colleagues to investigate the relevance and responsiveness of wellbeing measures in the context of MS, and undertaking further work to explore the impact on cost-effectiveness results of using the MSIS-8D, compared to generic preference-based measures such as the EQ-5D and SF-6D. She also provides health economics support to colleagues undertaking clinical trials.

Research projects

Putting the "Q" into QALYs for multiple sclerosis: Estimating quality-adjusted life-years (QALYs) for use in multiple sclerosis research and health policy settings (PhD studentship, funded by the Multiple Sclerosis Society of Great Britain and Northern Ireland, 2011-2014)

Extending the evidence on quality adjusted life years (QALYs) in MS-related research/ policy, and on the framework for cost-effectiveness analyses in the context of MS (Junior Fellowship, funded by the MS Society, 2015-2018)

Ensuring effective treatments are available to people with Multiple Sclerosis: addressing the value for money issue (Project Grant, funded by the MS Society, 2018-2021)

The health-related quality of life, fatigue severity, and walking limitations of people with Multiple Sclerosis by key socio-demographic and clinical characteristics: A cross-sectional and longitudinal analysis, incorporating a cost-effectiveness perspective (Project Grant, funded by the MS Society, 2018)

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Publications

Journal articles

Hawton A, Goodwin E, Boddy K, Freeman J, Thomas S, Chataway J, Green C (In Press). Measuring the cost-effectiveness of treatments for people with Multiple Sclerosis: beyond quality-adjusted life-years. Multiple Sclerosis Journal
Goodwin EA, Hawton A, Green C (In Press). Using the Fatigue Severity Scale to inform healthcare decision-making in multiple sclerosis: mapping to three quality-adjusted life-year measures (EQ-5D-3L, SF-6D, MSIS-8D). Health and Quality of Life Outcomes, 17(136). Abstract.
Goodwin E, Davey A, Green C, Hawton A (In Press). What drives differences in preferences for health states between patients and the public? a qualitative investigation of respondents' thought processes. Social Science and Medicine
Dhanda A, Andrade J, Allende H, Allgar V, Bailey M, Callaghan L, Cocking L, Goodwin E, Hawton A, Hayward C, et al (2024). Mental Imagery to Reduce Alcohol-related harm in patients with alcohol use disorder and alcohol-related liver damaGE: the MIRAGE randomised pilot trial results. BMJ Open Gastroenterol, 11(1). Abstract.  Author URL.
Wainwright TW, Parkinson EP, Immins T, Docherty S, Goodwin E, Hawton A, Low M, Samways J, Rees T, Saunders G, et al (2023). CycLing and EducATion (CLEAT): protocol for a single centre randomised controlled trial of a cycling and education intervention versus standard physiotherapy care for the treatment of hip osteoarthritis. BMC Musculoskelet Disord, 24(1). Abstract.  Author URL.
Heather A, Goodwin E, Green C, Morrish N, Ukoumunne OC, Middleton RM, Hawton A (2023). Multiple sclerosis health-related quality of life utility values from the UK MS register. Multiple Sclerosis Journal - Experimental, Translational and Clinical, 9(2). Abstract.
Swancutt D, Tarrant M, Ingram W, Baldrey S, Burns L, Byng R, Calitri R, Creanor S, Dean S, Evans L, et al (2022). A group-based behavioural intervention for weight management (PROGROUP) versus usual care in adults with severe obesity: a feasibility randomised controlled trial protocol. Pilot and Feasibility Studies, 8(1). Abstract.
Dhanda AD, Allende H, Allgar V, Andrade J, Bailey MP, Callaghan L, Cocking L, Goodwin E, Hawton A, Hayward C, et al (2022). Mental Imagery to Reduce Alcohol-related harm in patients with alcohol dependence and alcohol-related liver damaGE: the MIRAGE pilot trial protocol. BMJ Open, 12(5). Abstract.  Author URL.
Goodwin E, Hawton A, Whitty JA, Green C (2021). Exploring the Factors that Influence Workforce Participation for People with Multiple Sclerosis: a Discrete Choice Experiment. Journal of Occupational Rehabilitation Abstract.
Hawton A, Boddy K, Kandiyali R, Tatnell L, Gibson A, Goodwin E (2021). Involving Patients in Health Economics Research: "The PACTS Principles". Patient, 14(4), 429-434. Abstract.  Author URL.
Marsden J, Pavlou M, Dennett R, Gibbon A, Knight-Lozano R, Jeu L, Flavell C, Freeman J, Bamiou DE, Harris C, et al (2020). Vestibular rehabilitation in multiple sclerosis: study protocol for a randomised controlled trial and cost-effectiveness analysis comparing customised with booklet based vestibular rehabilitation for vestibulopathy and a 12 month observational cohort study of the symptom reduction and recurrence rate following treatment for benign paroxysmal positional vertigo. BMC Neurology, 20(1). Abstract.
Hawton A, Green C, Goodwin E, Harrower T (2019). Health state utility values (QALY weights) for Huntington's disease: an analysis of data from the European Huntington's Disease Network (EHDN). Eur J Health Econ, 20(9), 1335-1347. Abstract.  Author URL.
Callaghan L, Thompson TP, Creanor SC, Quinn C, Senior J, Green C, Hawton AJ, Byng R, Wallace G, Sinclair J, et al (2019). Individual health trainers to support health and well-being for people under community supervision in the criminal justice system: the STRENGTHEN pilot RCT. Public Health Research, 7(20).
Goodwin E, Green C, Hawton A (2018). Health State Values Derived from People with Multiple Sclerosis for a Condition-Specific Preference-Based Measure: Multiple Sclerosis Impact Scale–Eight Dimensions–Patient Version (MSIS-8D-P). Value in Health, 21(11), 1338-1345. Abstract.
Green C, Goodwin E, Hawton A (2017). "Naming and Framing": the Impact of Labeling on Health State Values for Multiple Sclerosis. Med Decis Making, 37(6), 703-714. Abstract.  Author URL.
Hawton AJ, Goodwin E, Boddy K, Tatnell L (2017). Involving members of the public in health economics research: Insights from selecting health states for valuation to estimate quality-adjusted life-year (QALY) weights. Applied Health Economics and Health Policy
Goodwin E, Green C (2016). A Systematic Review of the Literature on the Development of Condition-Specific Preference-Based Measures of Health. Appl Health Econ Health Policy, 14(2), 161-183. Abstract.  Author URL.
Goodwin E, Green C (2015). A Quality-Adjusted Life-Year Measure for Multiple Sclerosis: Developing a Patient-Reported Health State Classification System for a Multiple Sclerosis-Specific Preference-Based Measure. Value Health, 18(8), 1016-1024. Abstract.  Author URL.
Goodwin E, Green C, Spencer A (2015). Estimating a Preference-Based Index for an Eight-Dimensional Health State Classification System for Multiple Sclerosis. Value Health, 18(8), 1025-1036. Abstract.  Author URL.
Hawton A, Shearer J, Goodwin E, Green C (2013). Squinting through layers of fog: assessing the cost effectiveness of treatments for multiple sclerosis. Appl Health Econ Health Policy, 11(4), 331-341. Abstract.  Author URL.
Goodwin EA, Frew EJ (2013). Using programme budgeting and marginal analysis (PBMA) to set priorities: Reflections from a qualitative assessment in an English Primary Care Trust. Social science & medicine, 98, 162-168. Abstract.

Conferences

Goodwin EA, Hawton A, Green C (2018). Mapping Fatigue Severity Scale scores to utility values from three preference-based measures (EQ-5D, SF-6D and MSIS-8D). European Health Economics Association (EuHEA) Conference. 12th - 14th Jul 2018.
Goodwin EA, Hawton A, Davey A, Green C (2018). What were they thinking? Investigating what influences respondents’ preferences when answering time trade-off questions. European Health Economics Association (EuHEA) Conference. 12th - 14th Jul 2018.
Goodwin EA, Green C, Hawton A (2017). Quality-adjusted life-years from the perspective of people with multiple sclerosis. MS Frontiers. 29th - 30th Jun 2017.
Goodwin EA, Green C, Hawton A (2017). What difference does it make? a comparison of preferences elicited from the general population and from people with multiple sclerosis. World Congress of the International Health Economics Association (IHEA). 5th - 8th Jul 2017.
Goodwin E, Green C (2014). Improving the measurement of QALYs in multiple sclerosis: Estimating a preference-based index for use in deriving quality-adjusted life-years (QALYs) for multiple sclerosis.  Author URL.
Hawton A, Goodwin E (2014). Patients and health economists: working together to build a better research base for making decisions about the funding of treatments for MS. International Society for Quality of Life Research (ISOQOL). 15th - 18th Oct 2014.
Goodwin E, Green C (2013). Improving the measurement of QALYs in multiple sclerosis: Developing a patient-reported health descriptive system for use in deriving quality-adjusted life-years (QALYs) for multiple sclerosis.  Author URL.
Green C, Goodwin E (2013). Improving the measurement of quality of life adjusted years (QALYs) in multiple sclerosis: developing a patient-reported health descriptive system for use in deriving values fo multiple sclerosis-specific QALYs.  Author URL.

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Teaching

Liz provides teaching on the Health Economics module, for BSc Medical Sciences students specialising in Health Research.

Liz has also been involved in developing and delivering the following workshops for health service researchers and health and social care professionals:
• Introduction to Economic Evaluation
• Economic evaluation: Introduction to the EQ-5D, SF-6D and SF-12
• Counting the costs. Economic analysis: Introduction to the collection and costing of health care resource use data

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