COLLEGE OF MEDICINE AND HEALTH
Medicine, Nursing and Allied Health Professions

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Dr Dario Pacitti

Dr Dario Pacitti

Postdoctoral Research Fellow

 01392 72 6024

 Medical School Building F.08C

 

Medical School Building, St Luke's Campus, Magdalen Road, Exeter, EX1 2LU, UK

Overview

Dr Pacitti graduated with a BSc in Pharmacology before obtaining his PhD in Cell biology and Genetics from St George’s, University of London. After his PhD, he continued his work as postdoctoral research assistant at St George’s University of London, where he investigated the role of thymidine phosphorylase in CNS maintenance and collaborated on progressing a European clinical trial for a novel enzyme replacement therapy for Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE). His research background is therefore in rare mitochondrial and neurological disorders. He is deeply interested in inflammation in the context of lung and CNS diseases, with a particular interest in disease modelling using complex in vitro systems such as 3-D cultures and organoids.

He has now joined Professor Matt Whiteman as a Postdoctoral Research Fellow in Inflammatory Pharmacology, working on mitochondria-targeted H2S donors against inflammation.

Links

Qualifications

  • BSc (Hons)
  • PhD

Research group links

Research

Research interests

Mitochondrial biology, inflammation, iPSCs, disease modelling, gene editing, transcriptomics, organoids, respiratory diseases.

Research projects

Current Projects:

  • Currently investigating the efficacy of mitochondria-targeted H2S donors in lung disease.

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Levene M, Bain MD, Moran NF, Nirmalananthan N, Poulton J, Scarpelli M, Filosto M, Mandel H, MacKinnon AD, Fairbanks L, et al (2019). Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy. J Clin Med, 8(4). Abstract.  Author URL.

Publications by year


2019

Levene M, Bain MD, Moran NF, Nirmalananthan N, Poulton J, Scarpelli M, Filosto M, Mandel H, MacKinnon AD, Fairbanks L, et al (2019). Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy. J Clin Med, 8(4). Abstract.  Author URL.

Dario_Pacitti Details from cache as at 2019-05-26 02:17:48

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Teaching

Supervision / Group

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